Search Results
Results 101 - 150 of 4761
1 2 3 4 5 6 7 8 9 10 >
Doycheva Deshka D Centre for Ophthalmology, University of Tuebingen, Tuebingen, - - 2014
To assess the long-term efficacy and tolerability of both derivatives of mycophenolic acid, mycophenolate mofetil (MMF) and mycophenolate sodium (MPS), in the therapy of patients with birdshot chorioretinopathy (BSCR). Retrospective analysis of 24 patients (48 eyes) with BSCR, treated with MMF or MPS with a follow-up of at least 1 year. ...
Sibbald Cathryn C Department of Dermatology, University of Toronto, Toronto, Ontario, - - 2014
Cyclosporine is a systemic therapy used for control of severe atopic dermatitis (AD) in children. Although traditionally recommended at a dose of 5 mg/kg/day for 6 months, a longer duration of treatment may be necessary to bring a child with active and severe disease into remission. There are few data on the ...
Mungo B B Division of Thoracic Surgery, Department of Surgery, Johns Hopkins University School of Medicine, Baltimore, Maryland, - - 2014
Neoadjuvant therapy has proven to be effective in the reduction of locoregional recurrence and mortality for esophageal cancer. However, induction treatment has been reported to be associated with increased risk of postoperative complications. We therefore compared outcomes after esophagectomy for esophageal cancer for patients who underwent neoadjuvant therapy and patients ...
Yoshikawa Norishige N Department of Pediatrics, Wakayama Medical University, Wakayama City, - - 2014
In this multicenter, open-label, randomized controlled trial, we determined whether 2-month prednisolone therapy for steroid-sensitive nephrotic syndrome was inferior or not to 6-month therapy despite significantly less steroid exposure. The primary end point was time from start of initial treatment to start of frequently relapsing nephrotic syndrome. The pre-specified non-inferiority ...
Dressler Dirk D Movement Disorders Section, Department of Neurology, Hannover Medical School, Hannover, Germany, - - 2014
We sought to explore the therapeutic effect of botulinum toxin (BT) therapy by analysing the time between the BT application and the onset of its decrease (treatment duration, TD), the inter-injection interval (II), and the excess time (ET, ET = II-TD). For this we studied 59 patients (37 females, 22 males, age ...
von Scheidt W W I.Medizinische Klinik, Herzzentrum Augsburg-Schwaben, Klinikum Augsburg, Stenglinstr. 2, 86156, Augsburg, Germany, - - 2014
Limited data exist regarding baseline characteristics and management of heart failure with reduced ejection fraction (EF) in tertiary care facilities. EVITA-HF comprises web-based case report data on demography, comorbidities, diagnostic and therapy measures, quality of life, adverse events and 1-year follow-up of patients hospitalized for chronic heart failure and an ...
Li L L Barrow Neurological Institute, St. Joseph's Hospital and Medical Center, Phoenix, USA - - - 2014
Dysphagia is not uncommon after stroke. Dysphagia may delay the functional recovery and substantially affects the quality of life after stroke, mainly if lest untreated. To detect and treat dysphagia as early as possible is critical for patients' recovery after stroke. Electrical stimulation has been reported as a treatment for ...
Samuelkamaleshkumar Selvaraj S Christian Medical College Vellore, Tamil Nadu, INDIA. Electronic address: - - 2014
To investigate the effectiveness of MT combined with bilateral arm training and graded activities to improve motor performance in the paretic upper limb following stroke. Randomized, controlled, assessor - blinded study. Inpatient stroke rehabilitation center of a tertiary care teaching hospital. Twenty patients with first time ischemic or hemorrhagic stroke, ...
Micek Scott T ST Division of Pharmacy Practice, St. Louis College of Pharmacy, St. Louis, - - 2014
Inappropriate initial therapy for Candida-related septic shock is common and associated with a high mortality rate. This before-after pilot study was conducted to determine the feasibility of using empiric therapy for reducing the time to appropriate antifungal therapy in patients with Candida-related septic shock. Patients aged 18-99years with septic shock ...
Oscroft Nicholas S NS Respiratory Support & Sleep Centre, Papworth Hospital NHS Foundation Trust, Papworth Everard, Cambridgeshire CB23 3RE, United Kingdom. Electronic address: - - 2014
The addition of domiciliary non-invasive ventilation (NIV) to standard therapy in chronic obstructive pulmonary disease (COPD) patients with compensated ventilatory failure (CVF) is reported to have beneficial effects. Compliance with NIV is an important factor. Volume assured NIV (va-NIV) may improve compliance and ventilation during sleep by automatically titrating ventilatory ...
Nussbaum Daniel P DP Duke University, Department of Surgery, USA. Electronic address: - - 2014
Neoadjuvant radiation therapy (RT) has several theoretical benefits in the treatment of retroperitoneal sarcoma (RPS), but concerns remain about treatment toxicity and perioperative morbidity. There are limited data regarding its effect on perioperative outcomes, most of which come from small, single-institution series. The purpose of this study was to evaluate ...
Yoshioka Daisuke D Department of Cardiovascular Surgery, Osaka University Graduate School of Medicine, 2-2 Yamadaoka, Suita, Japan, - - 2014
The aim of this study was to evaluate our clinical experience with the Jarvik 2000 axial flow pump (Jarvik Heart, Inc, New York, NY, USA), a miniature axial flow left ventricular assist device (LVAD). The clinical results of eight patients, who underwent LVAD implantation with the Jarvik 2000 (median age ...
Haegeli Laurent M LM Clinic for Cardiology, University Heart Center, University Hospital Zurich, Raemistrasse 100, CH-8091 Zurich, - - 2014
Catheter ablation of atrial fibrillation (AF) is now an important therapeutic modality for patients with AF. There is considerable evidence available from several prospective randomized trials demonstrating that catheter ablation of AF is superior to antiarrhythmic drug therapy in controlling AF and that AF ablation improves quality of life substantially. ...
Jódar-Sánchez Francisco F Technological Innovation Group, Virgen del Rocío University Hospital, Seville, Spain Andalusian Public Foundation for Health Research Management in Seville, Seville, - - 2014
We conducted a cost-utility analysis of a telehealth programme for patients with severe chronic obstructive pulmonary disease (COPD) compared with usual care. A randomized controlled trial was carried out over four months with 45 patients treated with long-term oxygen therapy, 24 in the telehealth group (TG) and 21 in the ...
Gomes Beatriz Fiuza BF Department of Ophthalmology, Federal University of Rio de Janeiro, Rio de Janeiro, - - 2014
To investigate the mean intraocular pressure (IOP) of patients with connective tissue disease (CTD) on low-dose chronic systemic corticosteroid therapy and compare with control subjects. Cross-sectional comparative study. A total of 86 patients with CTD were grouped according to corticosteroid therapy. Group 1 (n = 27) was composed of patients ...
Matin Marzieh - - 2014
Abstract Objectives: Usage of 308-nm excimer laser (EL) is an effective treatment in vitiligo. As genetic predispositions along with type of skin and sun exposure rate are known factor influencing the treatment outcomes we tried to evaluate treatment results of using 308nm-excimer laser alone in comparison with combined therapy of ...
Huang Congwu C Department of Gastroenterology, the Second Affiliated Hospital of Shantou University , Shantou , - - 2014
Abstract Context: Proton pump inhibitor (PPI) increases the risk of decrease in bone mineral density (BMD). However, whether calcitrol improves this situation is unknown. Objective: The current study investigates the effects of calcitriol on BMD in patients with esomeprazole therapy. Materials and methods: Three hundred and eighty-six participants with gastrointestinal ...
Zhou YuQian Y Department of Gastroenterology, The 2nd Affiliated Hospital of XiangYa Medical School, Central South University , Changsha, Hunan, China - - 2014
Abstract Introduction: This study aimed to assess the safety and effectiveness of covered self-expanding metal stents for the treatment of nonvariceal esophageal bleeding in patients for whom routine therapies have failed. Patients and Methods: A retrospective analysis was conducted on patients with esophageal bleeding in our hospital. Data on hemostatic ...
Erdei Annamaria A Division of Endocrinology, Insitute of Medicine, University of Debrecen , Debrecen , Hungary - - 2014
Abstract The aim of this investigations was to study the effectiveness of anti-CD20 antibody therapy in Graves' orbitopathy (GO) resistant to glucocorticoids. Five patients were entered in the study. The protocol required no improvement of orbital status after a recent course of glucocorticoids. Activity of GO was confirmed by three ...
Papadopoulos N N Division of Thoracic and Cardiovascular Surgery, University Frankfurt/Main, Germany - - 2014
Risk factors for adverse outcome after extracorporeal life support (ECLS) are yet to be defined. For this purpose, we reviewed our institutional data from more than a decade, focusing on patients with ECLS. Between December 2001 and June 2013, 360 consecutive cardiac surgical patients received ECLS for post-cardiotomy cardiogenic shock, ...
Lavery Lawrence A LA Department of Plastic Surgery, University of Texas Southwestern, Dallas, TX, - - 2014
In a randomised, controlled study, we compared the efficacy of Grafix(®) , a human viable wound matrix (hVWM) (N = 50), to standard wound care (n = 47) to heal diabetic foot ulcers (DFUs). The primary endpoint was the proportion of patients with complete wound closure by 12 weeks. Secondary endpoints included the time to ...
Pekyavaş Nihan Özünlü NO Baskent University, Faculty of Health Sciences, Department of Physiotherapy and Rehabilitation, Baglıca 06810, Ankara, Turkey. Electronic address: - - 2014
The purpose of our study was to investigate the effects of Kinesio Taping(®) Application with Complex Decongestive Therapy (CDT) in patients with lymphedema. 45 patients were randomly divided into 3 groups (CDT including Bandage, CDT including Bandage + Kinesio Tape(®), CDT including Kinesio Tape(®) without bandage). Assessments included the severity of the ...
Llaó Jordina J Hospital de la Santa Creu i Sant Pau (Barcelona), Universitat Autònoma de Barcelona, Catalonia, - - 2014
Oral corticosteroids remain the mainstay of treatment for moderately active ulcerative colitis (UC). In patients who fail to respond to oral corticosteroids, attempting the intravenous route before starting rescue therapies is an alternative, although no evidence supports this strategy. To evaluate clinical outcomes after a course of intravenous corticosteroids for ...
Suzuki Tomoyuki T Division of Cardiovascular Surgery, Tohoku University Graduate School of Medicine, 1-1 Seiryocho, Aoba-ku, Sendai, 980-8574, - - 2014
Once a replaced prosthetic graft is infected, it is usually necessary to re-replace the thoracic aorta to achieve complete resolution of the infection. It is, however, an exceedingly invasive approach to perform such a repeat surgery on patients in a poor condition. We have managed both re-replacement of an infected ...
Silva Geisa Badauy Lauria GB Hematopoietic Stem Cell Transplant Unit, Araújo Jorge Hospital, Associação de Combate ao Câncer de Goiás, Goiânia, Goiás, - - 2014
Patients undergoing hematopoietic stem cell transplantation (HSCT) are submitted to a conditioning regimen of high-dose chemotherapy, with or without radiation therapy, which usually results in oral ulcerations and mucosal barrier breakdown. Oral mucositis (OM) is a common and debilitating toxicity side effect of autologous and allogeneic HSCT. The aim of ...
Molander Pauliina P Maria Helsinki City Hospital and University of Helsinki, Helsinki, Finland. Electronic address: - - 2014
This prospective multicenter study examined whether elevated fecal calprotectin (FC) concentrations after stopping TNFα-blocking therapy can predict clinical or endoscopic relapse. In addition, we evaluated the impact of histological remission on the relapse risk. We enrolled inflammatory bowel disease (IBD) patients who were in clinical, endoscopic, and FC-based (<100μg/g) remission ...
Busetto Gian Maria - - 2014
Bacterial prostatitis (BP) is a common condition accounting responsible for about 5-10% of all prostatitis cases; chronic bacterial prostatitis (CBP) classified as type II, are less common but is a condition that significantly hampers the quality of life, (QoL) because not only is it a physical condition but also a ...
Samy Nevien A NA Dermatology Unit, Department of Medical Applications of Laser, National Institute of Laser Enhanced Sciences (NILES), Cairo University, Cairo, Egypt, - - 2014
Photodynamic therapy (PDT) is regarded as a treatment option for basal cell carcinoma (BCC). The aim of this study is to investigate the efficacy of methylene blue (MB)-based PDT in patients suffering from nodular or ulcerative BCCs. This study is a prospective clinical trial with a 6-months follow-up. The study ...
Saka Yosuke Y Department of Internal Medicine, Kasugai Municipal Hospital, 1-1-1 Takakicho, Kasugai, 486-8510, Aichi, Japan, - - 2014
Catheter malposition is one of the reasons for outflow failure in peritoneal dialysis (PD) patients. Fluoroscopic manipulation is a non-surgical treatment option for catheter malposition. We retrospectively analyzed the efficacy and safety of fluoroscopic manipulation using an alpha-replacer guidewire. The alpha-replacer (JMS Co. Ltd., Tokyo, Japan) is a guidewire for ...
Ragaie Al-Helow M M Department of Physical Medicine & Rehabilitation, Ain Shams University, Egypt - - - 2014
Modified constraint induced movement therapy (m--CIMT) discourages the use of the unaffected extremity and encourages the active use of the hemiplegic arm in order to restore the motor function. To assess the efficacy of modified constraint induced movement therapy (m--CIMT) on functional recovery of upper extremity (UE) in acute stroke ...
Bech Anneke P AP Department of Nephrology, Radboud University Medical Centre, Nijmegen, The Netherlands; and - - 2014
The optimal timing and duration of immunosuppressive therapy for idiopathic membranous nephropathy (iMN) have been debated. This study aimed to evaluate whether measuring the antibody against the phospholipase A2 receptor (PLA2R-ab) at start and end of therapy predicts long-term outcome and therefore may inform this debate.DESIGN, SETTING, PARTICIPANTS, & MEASUREMENTS: ...
Nagappa M M Department of Neurology, National Institute of Mental Health and Neurosciences (NIMHANS), Hosur Road, Bangalore, Karnataka 560 029, - - 2014
Myasthenia gravis (MG) is a chronic autoimmune disorder with a fluctuating clinical course. The aim of immunotherapy is to bring about long-term remission. We evaluated the safety and efficacy of cyclophosphamide in generalized MG. We also highlight the limitations of cyclophosphamide therapy in inducing long-term remission. Data from 22 patients ...
Yaşar Zehra Aşuk ZA The Department of Sleep Disorders, Dr Suat Seren Chest Diseases and Surgery Training and Research Hospital, Yenisehir, 35110, Izmir, Turkey, - - 2014
Urinary albumin is a marker of cardiovascular morbidity and mortality, and also it has been viewed as a marker for vascular endothelial dysfunction in both the kidneys and systemic vasculature. Lowering urinary albumin is associated with fewer cardiovascular and renal diseases. We investigated the change in urinary albumin after 1 month ...
Moreira Amanda C AC Institute of Medicine and Dermatology (ISMD), São Paulo, SP, - - 2014
Facial aging is a natural biological process with symptoms such as sagging tissue, accentuated lines, furrows, wrinkles, dyschromias, and loss of facial volume. Rhytidectomy alone often fails to achieve a patient's expected goals, which is why there is a high demand for adjunct laser skin treatment. From January 2007 to ...
Sinha Aditi A Division of Nephrology, Department of Pediatrics, All India Institute of Medical Sciences, New Delhi, - - 2014
While studies show that prolonged initial prednisone therapy reduces the frequency of relapses in nephrotic syndrome, they lack power and have risk of bias. In order to examine the effect of prolonged therapy on frequency of relapses, we conducted a blinded, 1:1 randomized, placebo-controlled trial in 5 academic hospitals in ...
Higgins Peter Dr PD Division of Gastroenterology, Department of Medicine, University of Michigan, Ann Arbor, Michigan, United States. Electronic address: - - 2014
& Aims: We investigated whether treatment of active inflammatory bowel disease with biologic agents is associated with a reduced risk of venous thromboembolic events (VTEs), compared with corticosteroid therapy. We performed a retrospective analysis of 15,100 adults with inflammatory bowel disease, identified from the Truven Health MarketScan® databases. We analyzed ...
Takayama Hiroo H Department of Surgery, Columbia University Medical Center, New York, NY - - 2014
-Mortality for refractory cardiogenic shock (RCS) remains high. In this patient cohort there have been mixed results in mechanical circulatory support device use as a bridge-to-decision therapy. We evaluated a continuous-flow external ventricular assist device (VAD), CentriMag VAD (Thoratec Corp., Pleasanton, CA), in patients with various etiologies of RCS. -This ...
Okamura Kenichi K Department of Cardiovascular Surgery, Tsukuba Memorial Hospital. Electronic address: - - 2014
Spontaneous isolated dissection of the superior mesenteric artery (SIDSMA) is a rare and potentially fatal disease. Several therapeutic options are available, including conservative therapy, endovascular repair, and open surgery. Herein, we report our experiences in the treatment of SIDSMA. Between February 2009 and June 2013, 17 patients were diagnosed as ...
Kahrilas P J PJ Division of Gastroenterology and Hepatology, Feinberg School of Medicine, Northwestern University, Chicago, IL, - - 2014
Little is known regarding patient characteristics that influence the speed of reflux oesophagitis (RO) healing. To investigate patient characteristics that may influence RO healing rates. A post hoc analysis of clinical trial data for potent acid suppression treatment of RO (esomeprazole or AZD0865) was conducted. Group A underwent endoscopy at ...
Ji Sang Gu SG Department of Physical Therapy, Eulji University Hospital, Daejeon, Republic of - - 2014
To investigate the effect of mirror therapy on the gait of patients with subacute stroke. Randomized controlled experimental study. Outpatient rehabilitation hospital. Thirty-four patients with stroke were randomly assigned to two groups: a mirror therapy group (experimental) and a control group. The stroke patients in the experimental group underwent comprehensive ...
Meyer Jacob C JC The Retina Institute, 1600 S. Brentwood Blvd., Suite 800, St. Louis, MO, 63144, USA, - - 2014
The optimal management approach to retinal arterial macroaneurysms (RAM) is unknown. This paper compares long-term outcomes in RAM treated with laser therapy versus observation. This is an IRB-approved retrospective study of patients with symptomatic RAM. Charts of patients with a diagnosis of RAM causing symptomatic visual loss were reviewed. Patients ...
Ma Jinlan J Department of Heallth Care, Qilu Hospital of Shandong University, Jinan, - - 2014
To evaluate the effect of photodynamic therapy (PDT) on central serous chorioretinopathy (CSC) compared with laser therapy and intravitreal injection of anti-vascular endothelial growth factor (anti-VEGF) drugs, and to find the maximum treatment effect with minimal dose and fluence of PDT. A systematic electronic search was conducted in Feb 2013 ...
Park Hyoung-Chul HC Department of Surgery, Hallym University College of Medicine, 896 Pyeongchon-Dong, Dong An-Gu, Anyang 431-070, Republic of - - 2014
Although many patients receive antibiotic therapy for uncomplicated appendicitis, the relatively high treatment failure and recurrence rates are problematic. We assumed that patients with appendicitis and appendiceal diameters ≤10 mm, have better outcomes. The purpose of this prospective non-randomized study was to assess the outcomes of antibiotic therapy in patients with ...
Szulik Mariola M Department of Cardiology, Congenital Heart Diseases and Electrotherapy, Silesian Center for Heart Diseases, Silesian University of Medicine, Silesia, - - 2014
We investigated the relationship between sleep-disordered breathing (SDB), cardiac function, and cardiac resynchronization therapy (CRT). Fifty-five CRT patients with SDB diagnosed by Holter ECG (apnea/hypopnea index - AHI) were included in the study. We sought to determine right ventricle (RV) predictors of short-term SDB improvement and long-term outcome in patients ...
Fukuchi Takumi - - 2014
Early induction with biologics can reduce complications in patients with Crohn's disease (CD) and improve their quality of life. The safety of biologics, however, is uncertain. Granulocyte and monocyte adsorptive apheresis (GMAA) is a natural biologic therapy that selectively removes granulocytes and monocytes/macrophages and has few severe adverse effects. The ...
Rozera Gabriella G National Institute for Infectious Diseases L. Spallanzani, Rome, - - 2014
Tropism evolution of HIV-1 quasispecies was analysed by ultra-deep pyrosequencing (UDPS) in patients on first-line combination antiretroviral therapy (cART) always suppressed or experiencing virological failure episodes. Among ICONA patients, two groups of 20 patients on cART for ≥5 years, matched for baseline viraemia and therapy duration, were analysed [Group I, ...
Franke Melanie - - 2014
Purpose: To evaluate how periodontitis patients perceive the outcome after long-term supportive therapy. Materials and Methods: 281 patients (150 women/131 men) with a mean age of 55 years (range: 45-86 years) were randomly selected and consecutively interviewed using a questionnaire designed for laypersons. All patients had shown high compliance with ...
Hong Jeong-Ho JH Department of Neurology, Keimyung University Dongsan Medical Center, Daegu, - - 2014
We aimed to describe the current status and clinical outcomes of recanalization therapy for internal carotid artery occlusion (ICAO) presenting as acute ischemic stroke. Using a nationwide stroke registry database in Korea, we identified consecutive ischemic stroke patients with ICAO hospitalized within 12 hours of onset between March 2010 and November 2011. ...
Lettieri C C Neurology Unit, 'S. Maria della Misericordia' University Hospital, Udine, - - 2014
Bilateral globus pallidus deep brain stimulation (GPi-DBS) represents an effective and relatively safe therapy for different forms of refractory dystonia. The aim of this study was to assess, retrospectively, the effect of two different stimulation settings during GPi-DBS in 22 patients affected by primary generalized or multi-segmental dystonia. Thirteen patients ...
Zhu RuoFu - - 2014
Anterior cervical discectomy and fusion (ACDF) was one of the preferred treatments for degenerative cervical spondylosis. However, the motion of adjacent segment was significantly increased after operation. So cervical disc arthroplasty have been suggested to keep the motion of adjacent segment. A new implant named dynamic cervical implant (DCI) has ...
1 2 3 4 5 6 7 8 9 10 >