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Kurre Wiebke W Klinik für Neuroradiologie, Neurozentrum, Klinikum Stuttgart, Kriegsbergstrasse 60, 70174, Stuttgart, Germany, - - 2014
The purpose of this study was to evaluate the safety and efficacy of the pREset stent retriever in a real-world clinical setting. Patients treated with pREset were selected from a prospectively maintained single-center database. A TICI score ≥2b after ≤3 passes was regarded as successful recanalization. All device-related complications and ...
Yan D D Department of Surgery, Jinling Hospital, Medical School of Nanjing University, Nanjing, - - 2014
Background/Objectives:Enterocutaneous fistula (ECF) is a serious complication of Crohn's disease (CD). Enteral nutrition (EN) is believed as one of therapeutic strategies of CD. This study is dedicated to identify predictors of response to EN in CD, which may lead to a better selection of fistula patients for this therapy.Subjects/Methods:Forty-eight CD ...
Zerwes Sebastian S Department of Vascular surgery, Klinikum Augsburg, - - 2014
ObjectiveFifty patients with complex aortic disease, who received hybrid treatment of the aortic arch with supra-aortic debranching and endovascular stent-graft repair, were evaluated in regard to events of primary (survival and technical success) and secondary (procedure-related complications) interest.MethodsThe single-center study was conducted over an eight-year period from December 2004 to ...
Wu Jeng-Yih JY Division of Gastroenterology, Department of Internal Medicine, Kaohsiung Medical University Hospital, Kaohsiung, Taiwan; Department of Medicine, Faculty of Medicine, College of Medicine, Kaohsiung Medical University, Kaohsiung, Taiwan; Division of Internal Medicine, Kaohsiung Municipal Ta-Tung Hospital, Kaohsiung, - - 2014
The need for new effective Helicobacter pylori eradication therapy has focused efforts on the development and optimization of regimens with excellent eradication rates such as 14-day hybrid therapy. This study evaluated whether the duration of hybrid therapy could be reduced while maintaining a high eradication rate and to examine the ...
Hamai Y Y Department of Surgical Oncology, Research Institute for Radiation Biology and Medicine, Hiroshima University, Hiroshima, - - 2014
We compared the surgical outcomes between 114 patients who did not receive neoadjuvant therapy (group 1) and 92 others who received neoadjuvant chemoradiotherapy (nCRT) (group 2), and assessed the preoperative and surgical factors that influence postoperative morbidity to determine the impact of nCRT on morbidity and mortality after esophagectomy via ...
Kuwayama Yasuaki Y Fukushima Eye Clinic, Fukushima-ku, Osaka, Japan, - - 2014
This study investigated the intraocular pressure (IOP)-lowering effects and safety of tafluprost ophthalmic solution 0.0015% in actual clinical practice. We started a mandatory prospective 2-year observational study, which collected IOP, conjunctival hyperemia score, corneal staining score, and adverse event data from glaucoma and ocular hypertension (OH) patients not previously treated ...
Ohba Seigo S Division of Dentistry and Oral Surgery, Department of Sensory and Locomotor Medicine, Faculty of Medical Sciences, University of Fukui, 23-3 Shimoaizuki, Matsuoka, Eiheiji-cho, Yoshida-gun, Fukui, 910-1193, Japan, - - 2014
It has been proposed that minor oral surgery can be performed safely in patients taking antithrombotic therapy without interrupting treatment; however, there is little evidence-based guidance about how to manage postoperative hemorrhage in patients taking antithrombotics, and few randomized trials that help to inform the risk-benefit ratio of continuing or ...
Kim Seung Young SY Division of Gastroenterology and Hepatology, Department of Internal Medicine, Korea University College of Medicine, Seoul, - - 2014
Recurrence of Helicobacter pylori (H. pylori) infection is the result of either recrudescence or reinfection. Annual recurrence rates per patient-year of follow-up have been reported to vary across countries. The aim of this study was to analyze recurrence rates of H. pylori after first-line and second-line eradication therapies in Korea. From 2007 ...
Xiao Shu-Ping SP Department of Gastroenterology, First Affiliated Hospital of Nanjing Medical University , Nanjing , - - 2014
Abstract Objectives. To evaluate the available data on the efficacy and safety of levofloxacin-based triple therapy compared with standard triple therapy in first-line treatment for Helicobacter pylori infection. Methods. By searching MEDLINE, The Cochrane Central Register of Controlled Trials, and Web of Knowledge, two independent reviewers systemically identified randomized controlled ...
Ueda Paulo Hitoshi - - 2014
Purpose: To evaluate the effect of different maintenance recall intervals in patients with chronic periodontitis treated by full-mouth ultrasonic debridement. Materials and Methods: Twenty-eight patients participated in the study and were divided into two groups: group 1 (n = 14) underwent full-mouth ultrasonic debridement followed by monthly supportive periodontal therapy; ...
Shimada Noritomo N Division of Gastroenterology and Hepatology, Shinmatsudo Central General Hospital, 1-380 Shinmatsudo, Matsudo, Chiba, 270-0034, - - 2014
The sustained virological response (SVR) rate of non-responders to peginterferon and ribavirin therapy (PR)is low for24-week telaprevir-based triple combination therapy (T12PR24), compared to that of treatment-naïve patients or previous-treatment relapsers.This study investigated which characteristics of non-responders were associated with a better SVR rate to 48-week therapy (T12PR48). A total of103 ...
Cho Ju-Yeon JY Division of Gastroenterology and Hepatology, Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, , Seoul, - - 2014
It is generally stated that oral antiviral therapy in patients with chronic hepatitis B (CHB) decreases the risk of developing hepatocellular carcinoma (HCC). Although oral nucleos(t)ide analogues (NUCs) may induce a state similar to inactive stage CHB, the long-term risk for HCC in patients treated with NUCs compared with inactive ...
Oh Koei K Division of Rheumatology, Niigata Rheumatic Center , Shibata, Niigata , - - 2014
Objectives. In order to verify combination therapy with drugs and surgery for rheumatoid arthritis (RA), we evaluated changes in clinical outcome affected by surgical intervention in the patient treated with biologics and investigated the effects of surgery on disease activity. Methods. Fifty-five lower limb joint surgeries were performed in 48 ...
van Nunen Michiel P M MP MOVE Research Institute Amsterdam, Faculty of Human Movement Science, VU University Amsterdam , Amsterdam , the Netherlands - - 2014
Abstract Purpose: This study investigates the effectiveness of Lokomat + conventional therapy in recovering walking ability in non-ambulatory subacute stroke subjects involved in inpatient rehabilitation. Method: Thirty first-ever stroke patients completed 8 weeks of intervention. One group (n = 16) received Lokomat therapy twice a week, combined with three times 30 min a ...
Kobayashi N N From the Department of Neurosurgery (N.K., Y.M., I.Y., T.I., M.E., H.A., K.I., H.T., I.K., K.N., K.K.) and Division of Molecular Epidemiology (M.U.), The Jikei University School of Medicine, Tokyo, - - 2014
The natural history and therapeutic management of dissecting vertebrobasilar aneurysms without ischemic or hemorrhagic stroke (nonstroke dissecting vertebrobasilar aneurysms) are not well-established. We conservatively followed patients with nonstroke dissecting vertebrobasilar aneurysms and evaluated the factors related to clinical and morphologic deterioration. One hundred thirteen patients were enrolled and divided by ...
Baguley Campbell C Dept of Otolaryngology, Wellington Hospital, Wellington, New Zealand; Applied Medical Research Centre, St. Vincent's Hospital, Sydney, - - 2014
Many chronic rhinosinusitis (CRS) treatment regimes revolve around "one-off" maximal medical therapy (MMT) protocols, and although many patients initially respond, long-term control is unpredictable. The value of imaging, endoscopy, and patient progress after MMT for CRS is assessed. Symptomatic CRS patients with computed tomography (CT)-confirmed disease were recruited at a ...
Mohite Prashant N PN Department of Cardiothoracic Transplantation and Mechanical Support, Royal Brompton and Harefield NHS Foundation Trust, London, Middlesex, UB9 6JH, UK, - - 2014
Synergy(®) micropump was implanted as a bridge to heart transplantation in a middle-age lady with chronic advanced heart failure due to dilated cardiomyopathy. After a good initial recovery, patient was discharged to ward, where her stay was prolonged due to non-healing operative wound over the micropump and recurrent gastrointestinal bleeding. ...
Pehlivan Yavuz Y Department of Rheumatology, School of Medicine, Uludag University, Bursa, Turkey, - - 2014
Pulmonary arterial hypertension (PAH) is a progressive and fatal disorder that any valuable advance in the management of diseases has crucial importance. The present study aimed to compare the Endothelin1 (ET1) inhibitor bosentan which is regarded as standard therapy with different dose regimens of palosuran which is urotensin-II (UII) inhibitor ...
Kolho Kaija-Leena KL Children's Hospital, Helsinki University Central Hospital , Helsinki, FIN-00029 , - - 2014
Abstract Objective. Monitoring fecal calprotectin (FC) could assist in the assessment of the therapeutic response of inflammatory bowel disease (IBD). There are few studies on long-term prognosis related to the FC value response to infliximab induction therapy, thus providing the aim of this study on pediatric patients. Methods. FC levels ...
Gille Jochen J Department of Anesthesiology, Intensive Care Medicine and Pain Therapy, St. Georg Hospital GmbH Leipzig, Germany. Electronic address: - - 2014
For critically ill patients, the use of regional citrate anticoagulation as part of continuous renal replacement therapy (CRRT) has become increasingly common in recent years. However, there are scarce data on the use of this technique in patients with burns. The aim of this study was to examine the effectiveness, ...
Luo Yongqi Y Department of Dermatology, Hunan Children's Hospital, Changsha, - - 2014
Six hundred thirty-five patients underwent oral propranolol treatment for infantile hemangioma. The efficacy rate was 91.2% and 162 of the patients recovered completely. No significant adverse effects were observed and the overall incidence of adverse effects was 2.1%.
Sehgal Virendra N VN Dermato-Venereology (Skin/VD) Center, Sehgal Nursing Home, Delhi, - - 2014
The trophic or chronic plantar ulcer of leprosy is one of the principle causes of disability and deformity in the disease and has been given due importance in the evolution of its classification. In view of the diversity of its clinical implications, the World Health Organization was obliged to bring ...
Wine Todd M TM Department of Otolaryngology, University of Colorado School of Medicine, Aurora2Children's Hospital of Colorado, - - 2014
IMPORTANCE Congenital nasal pyriform aperture stenosis (CNPAS) may require sublabial drill-out of the pyriform aperture when symptoms are severe or refractory to medical therapy. Less invasive nasal dilation decreases potential morbidity to neonates with severe CNPAS. OBJECTIVE To determine the outcome of patients with CNPAS who underwent nasal dilation alone ...
Uihlein Lily C LC Dermatology Program, Boston Children's Hospital, Boston, - - 2014
Partially empty sella with growth hormone (GH) deficiency is rarely reported in association with PHACE (posterior fossa anomalies, cervicofacial infantile hemangiomas [IHs], arterial anomalies, cardiac defects, eye anomalies, and midline/ventral defects). Consequently, little is known about the effect of GH replacement on the proliferation and involution of IHs in children ...
Schott T C TC Department of Orthodontics, Center of Dentistry, Oral Medicine, and Maxillofacial Surgery, Eberhard Karls University Tübingen, Osianderstr. 2-8, 72076, Tübingen, Germany, - - 2014
The goal of the present work was to determine the influence of screw activation rates and electronically tracked wear times on transverse maxillary expansion with removable orthodontic appliances. In all, 28 patients were included in an open prospective observational study covering approximately 6 months of maxillary transverse expansion. In each of these ...
Liu Chun-Fu CF 1 Department of Ophthalmology, Chang Gung Memorial Hospital , Keelung, Taiwan - - 2014
Abstract Purpose: This study evaluated the safety and efficacy of half-dose verteporfin combined with half-fluence photodynamic therapy (half-half photodynamic therapy (PDT) for chronic central serous chorioretinopathy (CSC). Methods: This was a retrospective case series. Fourteen eyes with chronic CSC receiving half-half PDT were included in group 1. Another 28 eyes ...
Harenberg Job J Department of Clinical Pharmacology, Medical Faculty Mannheim, Inorganic Chemistry Institute, Ruprecht-Karls-University Heidelberg, - - 2014
The oral direct factor Xa inhibitor apixaban is approved for prevention of ischemic stroke in patients with atrial fibrillation (1) and for prophylaxis of postoperative venous thromboembolism following elective knee or hip replacement surgery (2). Studies have shown efficacy and safety for patients with acute deep vein thrombosis compared to ...
Wilson Thomas J TJ Department of Neurosurgery, University of Michigan, 1500 E. Medical Center Drive, Room 3552 TC, Ann Arbor, MI, 48109-5338, USA, - - 2014
Thromboembolic events represent a clinically significant cause of neurological morbidity during the endovascular management of cerebral aneurysms. We have implemented an anti-thromboembolic regimen consisting of pre- and postoperative dual antiplatelet therapy, as well as postoperative anticoagulation using heparin and dextran. The aims of our study were to examine the effect ...
Kulisch A A St. Andrew Hospital for Rheumatic Diseases, Hévíz - - - 2014
Background: Osteoarthritis is the most frequent joint disease and is a leading cause of pain and locomotor disability in elderly people. The treatment of osteoarthritis includes nonpharmacological, pharmacological, and surgical therapies. Silver level evidence has been found concerning balneotherapy in osteoarthritis. Aim of the study: The aim of this study ...
McGuire Michael K MK Private Practice, Houston, - - 2014
Background: The standard of care for increasing keratinized tissue (KT) and vestibular area is an autogenous free gingival graft (FGG) and vestibuloplasty; however, there is morbidity associated with the harvest of autogenous tissue, and supply is limited. The purpose of this study was to determine if a xenogeneic collagen matrix ...
Lampe Christina C Department of Pediatric and Adolescent Medicine, Villa Metabolica, University Medical Center of Mainz, Mainz, Germany, - - 2014
No published clinical trial data are available to inform the use of enzyme replacement therapy (ERT) in patients with the severe (neuropathic) phenotype of mucopolysaccharidosis II (MPS II). Current guidelines recommend ERT administered intravenously be used on a trial basis in this population. A retrospective chart review was conducted at ...
Nishio Ryo R Kobe University Graduate School of Medicine, Division of Cardiovascular Medicine, Department of Internal Medicine, - - 2014
The addition of highly purified eicosapentaenoic acid (EPA) to statin therapy prevents cardiovascular events. However, the impact of this treatment on vulnerable plaques remains unclear. The aim of this study was to assess the impact of adding EPA to a standard statin therapy on vulnerable plaques by serial optical coherence ...
Irwin Adriane N AN Kaiser Permanente Colorado, Aurora, CO, United States. Electronic address: - - 2014
Although warfarin is often recommended for pulmonary arterial hypertension (PAH) management to mitigate thrombotic risk and improve survival, limited information exists to guide anticoagulation therapy. The purpose of this study was to compare and contrast warfarin therapy monitoring requirements and outcomes in patients with PAH and atrial fibrillation (AF) receiving ...
Abilleira Sònia S Hospital Arnau de - - 2014
We sought to assess outcomes after endovascular treatment/therapy of acute ischemic stroke, overall and by subgroups, and looked for predictors of outcome. We used data from a mandatory, population-based registry that includes external monitoring of completeness, which assesses reperfusion therapies for consecutive patients with acute ischemic stroke since 2011. We ...
Aoki Junya J Cerebrovascular Center, Neurological Institute, Cleveland Clinic, - - 2014
Diagnostic accuracies of standard NCCT, CTA, CTA-SI, FLAIR, and DWI to detect the diffusion-perfusion mismatch (DPM) were compared. Stroke patients considered for endovascular therapy within 8 hours of onset were enrolled. DPM was defined as at least 160% mismatch between DWI and PWI volume. DPM was seen in 35 (71%) ...
Brioli Annamaria A "Seràgnoli" Institute of Hematology, Bologna University School of Medicine, Bologna, - - 2014
The recent availability of novel agents has substantially improved the outcomes of patients with Multiple Myeloma (MM). Achieving the deepest level of complete response and maintaining a sustained remission are important steps towards MM cure. To achieve this goal, consolidation and maintenance therapies are currently incorporated into the modern therapeutic ...
Liew Wendy K M WK Department of Neurology, Boston Children's Hospital, Harvard Medical School, Boston, - - 2014
IMPORTANCE Juvenile myasthenia gravis (MG) is a relatively rare autoimmune disorder. The comparative efficacy of plasmapheresis (PLEX) vs immunoglobulin as maintenance therapy is unclear for this childhood disease. OBJECTIVE To determine whether PLEX or intravenous immunoglobulin (IVIG) therapy is more effective as maintenance therapy in this disease. DESIGN, SETTING, AND ...
Ebm Claudia C 1Department of Intensive Care Medicine, St. George's Healthcare Trust, London, United Kingdom. 2St. George's University of London, London, United - - 2014
Patients undergoing major surgery are at high risk of increased postoperative morbidity and mortality. Goal-directed therapy has been shown to improve outcomes when commenced in the early postoperative period, yet the economic impact remains unclear. The aim of our study was to assess the cost effectiveness of goal-directed therapy as ...
Kawamura Tetsuya T Division of Kidney and Hypertension, Department of Internal Medicine, Jikei University School of Medicine, Tokyo, - - 2014
The study aim was, for the first time, to conduct a multicenter randomized controlled trial to evaluate the effect of tonsillectomy in patients with IgA nephropathy (IgAN). Patients with biopsy-proven IgAN, proteinuria and low serum creatinine were randomly allocated to receive tonsillectomy combined with steroid pulses (Group A; n = ...
Hoshino Junichi J Nephrology Center, Toranomon Hospital, Tokyo, Japan. Electronic address: - - 2014
Hepatic transcatheter arterial embolization (TAE) has become an accepted treatment option for patients with symptomatic autosomal dominant polycystic kidney disease (ADPKD) who also have polycystic liver disease and who are not good candidates for surgery. However, indications for TAE and long-term outcome with it are still unclear. Retrospective cohort study. ...
Zhu Xin-Hua XH Department of Otorhinolaryngology Head and Neck Surgery, the Second Affiliated Hospital of Nanchang University, Nanchang 330006, - - 2014
To observe the clinical manifestations of allergic rhinitis mice and the expression changes of the eosinophils CCR3 and the granule protein mRNA in the bone marrow, peripheral blood and nasal lavage fluid. Twenty-four BALB/c mice were randomly divided into the control group, PBS therapy group, siRNA therapy group and the ...
Ferreira João Pedro JP Centro Hospitalar do Porto, Porto, - - 2014
Albuminuria is a robust, validated cardiovascular risk factor. It is a simple and widely available test that was shown to be a powerful and independent predictor of prognosis in chronic heart failure. Mineralocorticoid receptor antagonists may reduce the acute and chronic harmful effects of mineralocorticoid receptor activation on the kidney. ...
Hojo Masayuki M Division of Respiratory Medicine, National Center for Global Health and Medicine, Tokyo, Japan; Department of Respiratory Medicine, Juntendo University School of Medicine, Tokyo, - - 2014
Background: The clinical usefulness of fixed-dose maintenance therapy with salmeterol/fluticasone (SFC) and budesonide/formoterol combination inhaler (BUD/FM) has been established, though evidence of the long-term anti-inflammatory effects of these 2 inhalers are limited. Methods: Patients with moderate persistent adult asthma who had received SFC 50/250μg bid with well-control status were recruited. ...
Tuncel Umut U Department of Plastic Reconstructive and Aesthetic Surgery, Gaziosmanpasa University, Faculty of Medicine, Tokat, Turkey; email: - - 2014
Since the introduction of negative pressure wound therapy (NPWT), the physiological effects of various interface dressing materials have been studied. The purpose of this experimental study was to compare the use of loofah sponge to standard polyurethane foam or a cotton gauze sponge. Three wounds, each measuring 3 cm x ...
Pusch Tobias - - 2014
Tuberculosis is classified as either pulmonary or extra-pulmonary (EPTB). While much focus has been paid to pulmonary tuberculosis, EPTB has received scant attention. Moreover, EPTB is viewed as one wastebasket diagnosis, as "the other" which is not pulmonary. This is a retrospective cohort study of all patients treated for EPTB ...
Silveira V V Oral and maxillofacial Department Pontifícia Universidade do Rio Grande do Sul (PUCRS) Porto Alegre, RS, Brazil - - - 2014
Aim: The objective of this study was to compare integration of AlloDerm® acellular dermal grafts in animals subjected to non-ablative laser irradiation and animals not exposed to this therapy. Methods: Standardized AlloDerm® fragments measuring 5 mm² were grafted into the subcutaneous tissue overlying the calvaria in 32 Wistar rats. Laser ...
Springer Jason J From Department of Rheumatic and Immunologic Diseases (JS); Department of Quantitative Health Sciences (BN); and Center for Vasculitis Care and Research, Department of Rheumatic and Immunologic Diseases (CAL, GSH, AVF), Cleveland Clinic, Cleveland, Ohio. *Current affiliation: University of Kansas Medical Center, Kansas City, - - 2014
To determine outcomes in relation to duration of maintenance therapy in patients with granulomatosis with polyangiitis (Wegener's) (GPA), we conducted a retrospective chart review of patients with GPA seen at a single vasculitis center from 1992 to 2010. All patients achieved remission defined by a Birmingham Vasculitis Activity Score for ...
Kumar Santosh S Department of Urology, PGIMER (Postgraduate Institute of Medical Education and Research), Chandigarh, - - 2014
To compare the safety and efficacy of tamsulosin and tamsulosin with the phosphodiesterase-5 inhibitor tadalafil in combination with prednisolone as medical expulsive therapies for lower ureteric stones. Between July 2011 and December 2012, 62 adult patients presenting with distal ureteric stones sized 5 to 10 mm were randomized equally to ...
Olfat Mohammed M The Hospital for Sick Children, Toronto, - - 2014
Cytopenias including thrombocytopenia and autoimmune hemolytic anemia(AIHA) are common in childhood-onset SLE (cSLE) and may be refractory to conventional therapy with corticosteroids, IVIG and/or other immunosuppressives. Rituximab appears to be an effective therapy for cytopenias, although no long term studies have been completed, and few cSLE patients have been reported. ...
Fogel Itay I Schneider Children's Medical Center, Tel Aviv University, Petach Tikvah, - - 2014
In our previous prospective study we have demonstrated that the administration of Dexamethasone as an adjuvant therapy lead to a significant clinical and laboratory improvement in children with septic arthritis. This therapy has become accepted in some of the pediatric wards at Schneider's medical center. The aim of this study ...
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