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Foo Hong H Department of Microbiology and Infectious Diseases, Sydney South West Pathology Service, Liverpool, Sydney, NSW, - - 2014
Enterococci are an important cause of nosocomial and community-acquired infections, with bacteraemia being one of the most common presentations. Although inappropriate antimicrobial therapy has been associated with poorer outcomes in Enterococcus faecalis (EF) bacteraemia, the impact of antimicrobial choice, namely β-lactam versus glycopeptide therapy, has not been well described. We ...
Hirano Daisaku D Department of Urology, Higashi-matsuyama City Municipal Hospital , Higashi-matsuyama Saitama-ken , - - 2014
Abstract Objective. The aim of this study was to prospectively verify the relationship between the clinical efficacies of secondary hormone therapy for castration-resistant prostate cancer (CRPC) following first line hormone therapy and neuroendocrine differentiation (NED). Material and methods. Forty-six consecutive patients with CRPC following first line hormone therapy who were ...
Iba Toshiaki - - 2014
The severity of sepsis increases along with the degree of coagulation disorder, and a fulminant coagulation abnormality is recognized as disseminated intravascular coagulation (DIC). The mortality of sepsis-associated DIC remains as high as 40%, which is comparable to that of septic shock. Even though intensive research is ongoing, no established ...
Ticly Flavia G FG Department of Ophthalmology, University of Campinas (UNICAMP) , Campinas, São Paulo, Brazil - - 2014
Abstract Purpose: To determine the efficacy of topical ketorolac tromethamine in preventing cystoid macular edema (CME) after uncomplicated cataract surgery. Method: This single-center, prospective, double-masked, randomized clinical trial consisted of 81 patients who were scheduled for cataract surgery. Patients were randomized to receive hypromellose/dextran 70 as a placebo (n=44) or ...
Gonzalez-Serna Alejandro A BC Centre for Excellence on HIV/AIDS, Vancouver V6Z1Y6, BC, - - 2014
The aim of this study was to describe the rates and predictors of discontinuing first-line antiretroviral therapy in the different eras of treatment over a nearly 20 year period initiated in British Columbia between 1992 and 2010. All naive adults who started antiretroviral therapy (first-line antiretroviral therapy) at any hospital ...
Davidson Bruce L BL Division of Pulmonary and Critical Care Medicine,University of Washington School of Medicine, Seattle, - - 2014
IMPORTANCE Combined anticoagulant and aspirin therapy is associated with increased bleeding risk in patients with atrial fibrillation, but the bleeding risk of combined use of anticoagulant and nonsteroidal anti-inflammatory drugs (NSAIDs) is poorly documented. OBJECTIVE To estimate the bleeding risk of combined anticoagulant (rivaroxaban or enoxaparin-vitamin K antagonist [VKA]) and ...
Lee Minkyung M Gangnam Severance Hospital, Yosei University College of Medicine, Department of Nuclear Medicine, 211 Eonju-Ro, Gangnam-Gu, Seoul, Korea, Republic of, 135-720, +82-2-2019-3742 ; - - 2014
Abstract Background Most current guidelines suggest 1 or 2 weeks of low iodine diet (LID) before radioactive iodine ablation therapy (RAIT) to increase its efficacy in differentiated thyroid cancer (DTC) patients after total thyroidectomy. LID duration is particularly important for patients living in iodine excess areas. However, there is no ...
Bucaneve Giampaolo G Giampaolo Bucaneve, Stelvio Ballanti, and Albano Del Favero, Ospedale S. Maria della Misericordia, Perugia, Italy; Alessandra Micozzi, Giuseppe Gentile, and Robin Foà, "Sapienza" Università di Roma, Roma; Marco Picardi, A. O. Universitaria "Federico II," Napoli; Nicola Cascavilla, Ospedale Casa Sollievo della Sofferenza, IRCCS, San Giovanni Rotondo; Prassede Salutari, Ospedale Civile "Spirito Santo," Pescara; Giorgina Specchia, Università di Bari, Bari; Rosa Fanci, A. O. Universitaria "Careggi," Firenze; Mario Luppi, A. O. Universitaria Policlinico, Modena; Laura Cudillo, Policlinico Tor Vergata, Roma; Renato Cantaffa, A. O. "Pugliese Ciaccio," Catanzaro; Giuseppe Milone, Policlinico "Vittorio Emanuele," Catania; Monica Bocchia, Policlinico "S. Maria alle Scotte," Siena; Giovanni Martinelli, Istituto Europeo Oncologico, Milano; Massimo Offidani, A. O. Universitaria-Ospedali Riuniti, Ancona; Anna Chierichini, Ospedale S. Giovanni Addolorata, Roma; Francesco Fabbiano, Ospedali Riuniti, Palermo; Giovanni Quarta, Ospedale "A. Perrino," Brindisi; Valeria Primon, Ospedale SS Antonio e Biagio, Alessandria; Bruno Martino, A. O. "Bianchi-Melacrino-Morelli," Reggio Calabria; Annunziata Manna, ASL5, La Spezia; Eliana Zuffa, Ospedale S. Maria delle Croci, Ravenna; and Antonella Ferrari, A. O. Sant'Andrea, - - 2014
Empiric antibiotic monotherapy is considered the standard of treatment for febrile neutropenic patients with cancer, but this approach may be inadequate because of the increasing prevalence of infections caused by multidrug resistant (MDR) bacteria. In this multicenter, open-label, randomized, superiority trial, adult, febrile, high-risk neutropenic patients (FhrNPs) with hematologic malignancies ...
Shim Jae-Jun JJ Department of Internal Medicine, Kyung Hee University School of Medicine, Seoul, - - 2014
Analysis of alpha-fetoprotein (AFP) levels affords limited diagnostic accuracy because of the high false-positive rates, especially in those with active chronic hepatitis B (CHB). We measured AFP levels before and after commencement of oral antiviral therapy and explored the utility of these data in terms of early detection of hepatocellular ...
van Dussen Laura - - 2014
To evaluate the cost-effectiveness of enzyme replacement therapy (ERT) compared to standard medical care without ERT in the Dutch cohort of patients with type 1 Gaucher disease (GD I). Cost-effectiveness analysis was performed using a life-time state-transition model of the disease's natural course. Transition probabilities, effectiveness data and costs were ...
Wang Jingfeng J Department of Cardiology, Shanghai Institute of Cardiovascular Diseases, Zhongshan Hospital, Fudan University, No. 180, Fenglin Road, Shanghai, 200032, - - 2014
Pulmonary artery hypertension is correlated with poor clinical prognosis in patients with chronic heart failure. However, there is a paucity of data concerning the impact of baseline pulmonary artery systolic pressure (PASP) on clinical outcome after cardiac resynchronization therapy (CRT). The aim of the study is to evaluate the association ...
Chen Xuhui X Department of Ear, Nose and Throat, Yueyang Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai, - - 2014
To perform a systematic literature review to evaluate the type and timing of therapy for vocal fold paresis/paralysis after thyroidectomy and develop a primary decision-making pathway. Meta-analysis. Four databases and one journal were searched using the key words of "thyroidectomy," "vocal cord paresis/paralysis," and "therapy." Study quality was evaluated using ...
Grindstaff Terry L TL School of Pharmacy & Health Professions, Physical Therapy Department, 2500 California Plaza, Creighton University, Omaha, NE 68178, USA. Electronic address: - - 2014
Manual therapies, directed to the knee and lumbopelvic region, have demonstrated the ability to improve neuromuscular quadriceps function in individuals with knee pathology. It remains unknown if manual therapies may alter impaired spinal reflex excitability, thus identifying a potential mechanism in which manual therapy may improve neuromuscular function following knee ...
Rodríguez Elena Navarro EN Department of Surgery, University Hospital Reina Sofía, Córdoba, Spain. Electronic address: - - 2014
This study evaluated the use of TachoSil as an adjunctive therapy for reducing axillary lymphocele formation. Eighty-six patients diagnosed with breast cancer N+ and treated with axillary lymphadenectomy received a TachoSil patch in the axillary wound. Using a database of patients without placing a hemostatic patch, we applied a matched ...
Sorensen Per Soelberg PS Danish Multiple Sclerosis Center, Department of Neurology, Rigshospitalet and University of Copenhagen, Copenhagen, Denmark, - - 2014
A number of studies have reported flare-up of multiple sclerosis (MS) disease activity after cessation of natalizumab, increasing to a level beyond the pre-natalizumab treatment level. Our aim was to describe the development in clinical disease activity following cessation of natalizumab therapy in a large unselected cohort of highly active ...
Atsukawa Masanori M aDepartment of Internal Medicine, Division of Gastroenterology, Nippon Medical School Chiba Hokusoh Hospital, Inzai bInstitute of Clinical Medicine and Research (ICMR), Jikei University School of Medicine, Kashiwa cDivision of Gastroenterology and Hepatology, Shinmatsudo Central General Hospital, Matsudo, Chiba dDepartment of Internal Medicine, Division of Gastroenterology and Hepatology eDepartment of Internal Medicine, Division of Hematology, Nippon Medical School, Bunkyo-ku fDepartment of Internal Medicine, Division of Gastroenterology, Hakujikai Memorial Hospital, Adachi-ku, Tokyo, - - 2014
The addition of fluvastatin significantly improves sustained virological response (SVR) in pegylated interferon and ribavirin (peg-IFN/RBV) combination therapy for patients infected with the hepatitis C virus. However, the add-on effect on telaprevir-based triple combination therapy remains unknown. The aim of this study was to investigate the effect of fluvastatin on ...
Plog Benjamin A BA University of Rochester School of Medicine and Dentistry, Rochester, NY, USA; Department of Neurosurgery, Center for Translation Neuromedicine, University of Rochester Medical Center, Rochester, NY, USA; Department of Pathology, University of Rochester Medical Center, Rochester, NY, USA. Electronic address: - - 2014
Subarachnoid hemorrhage (SAH) is a neurologic catastrophe and poor outcome is typically attributed to vasospasm; however, there is also evidence that SAH causes a pro-inflammatory state and these two phenomena may be interrelated. SAH causes activation of microglia, but the time course and degree of microglial activation after SAH and ...
Mutoh Tatsushi T *Department of Surgical Neurology, Research Institute for Brain and Blood Vessels-AKITA, Akita ‡Department of Neurosurgery, Hokkaido University Graduate School of Medicine §Department of Neurosurgery, Teine Keijinkai Hospital, Sapporo †Department of Nuclear Medicine and Radiology, Institute of Development, Aging and Cancer, Tohoku University, Sendai, - - 2014
Recent clinical data suggest that postoperative hemodynamic profile and fluid management may differ in aneurysmal subarachnoid hemorrhage patients depending on the treatment option: surgical clipping or endovascular coiling. Our aim was to determine the differences in hemodynamic parameters between the 2 modalities using an advanced transpulmonary thermodilution technique. We studied ...
Peled Anne Warren AW * Division of Plastic & Reconstructive Surgery, Department of Surgery, University of California, San Francisco, San Francisco, CA † School of Medicine, Duke University; Durham, North Carolina # Division of Breast Surgery, Department of Surgery, University of California, San Francisco, San Francisco, CA ° Department of Radiation Oncology, University of California San Francisco; San Francisco, - - 2014
Postoperative complications after total skin-sparing mastectomy (TSSM) and expanderimplant reconstruction can negatively impact outcomes, particularly in the setting of postmastectomy radiation therapy (PMRT). The goal of this study is to determine if rates of ischemic complications after PMRT are impacted by TSSM incision. We queried a prospectively-collected database of patients ...
Steinberg Daniel H DH Divisions of Cardiology and Cardiothoracic Surgery, Medical University of South Carolina, 25 Courtenay Drive, ART 7031 MSC 592, Charleston, SC, 29425, - - 2014
The surgical treatment for valvular heart disease is well established with excellent long-term outcomes in appropriately selected patients. For patients at elevated risk for surgical intervention, options have traditionally been limited to medical therapy with disappointing results. The advent of transcatheter techniques of valvular repair or replacement has revolutionized treatment ...
Mayer K K Katharina Mayer, MD, Deutsches Herzzentrum München, Lazarettstr. 36, 80636 Munich, Germany, Tel: +49 89 1218 0, Fax: +49 89 1218 4013, E-mail: - - 2014
In clopidogrel treated patients undergoing percutaneous coronary intervention (PCI), high platelet reactivity (HPR) is associated with a higher risk for thrombotic events including stent thrombosis (ST). A personalised therapy with selective intensification of treatment may improve HPR patients´ outcome in this setting although recent randomised trials are against this hypothesis. ...
Shum Hoi-Ping HP Department of Intensive Care, Pamela Youde Nethersole Eastern Hospital (shumhp@ha.org.hk), ORCID: 0000-0001-7002-3548 Department of Intensive Care, Pamela Youde Nethersole Eastern Hospital (kmc804@ha.org.hk), ORCID: 0000-0001-6032-518X Department of Intensive Care, Pamela Youde Nethersole Eastern Hospital (chankck@ha.org.hk), ORCID: 0000-0002-1786-541X Department of Intensive Care, Pamela Youde Nethersole Eastern Hospital (yanww@ha.org.hk), ORCID: - - 2014
Patients on extracorporeal membrane oxygenation (ECMO) frequently requires continuous renal replacement therapy (CRRT). Additional anticoagulation for the CRRT circuit is usually not employed, but this may increases the risk of clot embolisation, which shortens oxygenator lifespan and increases patient's risk. We report our experience on the use of regional citrate ...
Shiraki Tatsuya T Kansai Rosai Hospital Cardiovascular Center, Hyogo, Japan. Electronic address: - - 2014
The latest guideline points to life expectancy of <2 years as the main determinant in revascularization modality selection (bypass surgery [BSX] or endovascular therapy [EVT]) in patients with critical limb ischemia (CLI). This study examined predictors and a predictive scoring model of 2-year mortality after revascularization. We performed Cox proportional hazards regression ...
Meyer Guy G The authors' affiliations are listed in the - - 2014
The role of fibrinolytic therapy in patients with intermediate-risk pulmonary embolism is controversial. In a randomized, double-blind trial, we compared tenecteplase plus heparin with placebo plus heparin in normotensive patients with intermediate-risk pulmonary embolism. Eligible patients had right ventricular dysfunction on echocardiography or computed tomography, as well as myocardial injury ...
Miki Kojiro K Cardiovascular Division, Hyogo College of - - 2014
Background: Although previous intravascular ultrasound (IVUS) studies reported that the drug-eluting stent (DES) has successfully decreased in-stent restenosis (ISR) by inhibiting neointimal hyperplasia (NIH) in the coronary artery lesion, no IVUS data for vascular response after DES implantation in the superficial femoral artery (SFA) have been published. Methods and Results: We retrospectively ...
Tarzia Vincenzo V Department of Cardiac, Thoracic and Vascular Sciences, Cardiac Surgery Unit, University of Padova, Padova, - - 2014
Sternal wound dehiscence (SWD) after cardiac surgery is a rare but serious condition associated with considerable costs and morbidity. We sought to evaluate the results of the introduction of vacuum-assisted closure (VAC) therapy in the management of sternal wound dehiscence, compared with those of previous conventional treatments. We retrospectively collected ...
Hoornweg Marije J MJ 4 Department of Plastic and Reconstructive Surgery, Netherlands Cancer Institute - Antoni van Leeuwenhoek Hospital, Amsterdam - The - - 2014
PurposeTo compare intralesional corticosteroid (IC) injections with oral propranolol in children with periorbital infantile hemangioma (IH).MethodsChildren were diagnosed with IH and treated with IC (n = 29) or propranolol (n = 14). In cases in which no further improvement was seen, treatment was stopped and the outcome measured. Type, duration, ...
Sun Zhiping - - 2014
Whether continuous venovenous hemofiltration (CVVHF) is superior to extended daily hemofiltration (EDHF) for the treatment of septic AKI is unknown. We compared the effect of CVVHF (greater than 72 hours) with EDHF (8 to 12 hours daily) on renal recovery and mortality in patients with severe sepsis or septic shock ...
Daniel William T WT Clinical Research Unit, Division of Cardiothoracic Surgery, Emory University School of Medicine, Atlanta, GA, - - 2014
The purpose of this study was to determine whether patients undergoing robotic-assisted coronary artery bypass graft surgery (CABG) on clopidogrel had an increased risk of bleeding complications compared with those not on clopidogrel. From 2008 to 2011, 322 patients underwent robotic-assisted CABG either as an isolated procedure or as part ...
Cayir A A Department of Pediatric Endocrinology, Regional Training and Research Hospital, Erzurum, - - 2014
The purpose of this study was to investigate the effect of supplementary vitamin D therapy in addition to amitriptyline on the frequency of migraine attacks in pediatric migraine patients. Fifty-three children 8-16 years of age and diagnosed with migraine following the International Headache Society 2005 definition, which includes childhood criteria, ...
Onyekwere Charles Asabamaka CA Charles Asabamaka Onyekwere, Joan Nwabuaku Odiagah, Rufina Igetei, Amancia Olufunmilayo Duro Emanuel, Francis Ekere, Gastroenterology unit, Department of Medicine, Lagos State University Teaching Hospital, Ikeja, Lagos 999062, - - 2014
To investigate the efficacy of a standard triple therapy (comprising rabeprazole, clarithromycin, and amoxicillin) for Helicobacter pylori (H. pylori) eradication, noting factors that influence the outcome and documenting any adverse events. Following institutional ethical approval, fifty consecutive and consenting symptomatic patients with evidence of H. pylori infection by either a ...
Man Shumei S Cerebrovascular Center, Neurological Institute, Cleveland Clinic, Cleveland, - - 2014
Intraarterial (IA) mechanical thrombectomy has an excellent recanalization rate but does not always correlate with good clinical outcomes. We aimed to investigate whether hyperdense middle cerebral artery sign (HMCAS) on preintervention nonenhanced CT (NECT) predicts IA therapy outcome for acute stroke. Data were abstracted from our Hyperacute Ischemic Stroke database. ...
Ko Young-Guk YG Severance Cardiovascular Hospital, Yonsei University Health - - 2014
Aim: The study aim is to investigate synergistic effects of cilostazol and probucol combination therapy on coronary plaque volume and composition. Methods: A total of 119 patients undergoing coronary stenting were treated with probucol and cilostazol combination therapy (group Ⅰ) or with cilostazol monotherapy (group Ⅱ) in a double-blind, randomized ...
Lee Dong-Yeop DY Department of Physical Therapy, SunMoon University, Asan, - - 2014
One of the major symptoms when women are wearing high heels for a long time is leg swelling. The purpose of this study was to compare the effect of manual lymph drainage with ultrasound therapy. The forty-five healthy women of twenties were participated in this study and divided randomly into ...
Diamant Michaela M Diabetes Centre, VU University Medical Centre, Amsterdam, Netherlands. Electronic address: - - 2014
When patients with type 2 diabetes start their first injectable therapy, clinicians can choose between glucagon-like peptide-1 (GLP-1) receptor agonists and basal insulins. In DURATION-3, exenatide once weekly was compared with insulin glargine (henceforth, glargine) as first injectable therapy. Here, we report the results of the final 3-year follow-up. DURATION-3 ...
van Loggerenberg Francois F CAPRISA, Nelson R Mandela School of Medicine, University of KwaZulu-Natal, Durban, South Africa, - - 2014
Concerns that standard didactic adherence counselling may be inadequate to maximise antiretroviral therapy (ART) adherence led us to evaluate more intensive individualised motivational adherence counselling. We randomised 297 HIV-positive ART-naïve patients in Durban, South Africa, to receive either didactic counselling, prior to ART initiation (n = 150), or an intensive motivational adherence ...
Yamada Naoki N Shimizu Hospital, 129, Miyagawa-Cho, Kurayoshi-City, Tottori, 682-0881, - - 2014
The purpose of this study was to assess the safety, feasibility and efficacy of continuous theta-burst stimulation (cTBS) combined with intensive occupational therapy (OT) for upper limb hemiparesis after stroke. Ten patients with history of stroke and upper limb hemiparesis (age 62.0 ± 11.1 years, time since stroke 95.7 ± 70.2 months, mean ± SD) were studied. Each ...
Rubin D T DT Inflammatory Bowel Disease Center, University of Chicago Medicine, Chicago, IL, - - 2014
Treatments for Crohn's disease (CD) and ulcerative colitis (UC) are not uniformly effective, thus necessitating dose changes, switching, and augmentation and carry adverse event risk, often requiring discontinuation, which reduces treatment benefits. To assess continuity of and changes to initial CD and UC treatments, as well as costs associated with ...
Shi Tian-Wei TW Department of Dermatology, the First Affiliated Hospital of Zhengzhou University, Zhengzhou, China; Department of Dermatology, People's Hospital of Zhengzhou, Zhengzhou, - - 2014
Hyperkeratotic-type tinea pedis is chronic and recalcitrant to topical antifungal agents. Some topical antifungal agents are effective; however, long duration of therapy is required, which often reduce the treatment compliance of patients. To seek for short period therapy of hyperkeratotic type tinea pedis, in this study, we observed the efficacy ...
Hahn Ezra E Department of Radiation Oncology, University of Toronto, Toronto, Ontario, - - 2014
Graves' ophthalmopathy (GO) is an autoimmune condition primarily managed with prolonged courses of glucocorticoids, which can be associated with significant side effects. Orbital radiation therapy (RT) is an alternative treatment that has shown variable efficacy in improving orbital and visual symptoms. In this study, the therapeutic benefit of RT was ...
Chun Byung-Joon BJ Department of Otolaryngology-Head and Neck Surgery, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea, 222 Banpo-daero, Seocho-gu, Seoul, 137-701, - - 2014
The objective of this study was to investigate the efficacy of early management of post-thyroidectomy unilateral vocal cord palsy (UVCP) and the clinical utility of the thyroidectomy-related voice questionnaire (TVQ) when planning UVCP treatment. The study group comprised 48 consecutive patients diagnosed with UVCP after thyroidectomy. Laryngoscopic examination and voice ...
Zou Yue Y Department of Articular Surgery, Affiliated Hospital of Qingdao University, Qingdao, Shandong Province, - - 2014
This study aimed to compare the efficacy and safety of aspirin, rivaroxaban and low-molecular-weight heparin (LMWH) for post total knee arthroplasty (TKA) deep vein thrombosis (DVT) prophylaxis. Between July 2011 and July 2013, a prospective randomized controlled trial was performed on 324 patients with osteoarthritis who underwent primary unilateral TKA. ...
Castilho F M FM Departamento de Clínica Médica, Faculdade de Medicina, e Serviço de Cardiologia e Cirurgia Cardiovascular, Hospital das Clínicas, Universidade Federal de Minas Gerais (UFMG), Belo Horizonte, - - 2014
Prosthetic heart valve thrombosis is a life-threatening condition for which treatment has not been evaluated by randomized trials. To compare surgery with thrombolytic therapy for the treatment of prosthetic valve thrombosis. A comprehensive systematic review was carried out by independent researchers in PubMed, Web of Knowledge, HINARI, LILACS and EMBASE; ...
Kondo Hiromu H Department of Gastroenterology and Metabolism, Nagoya City University Graduate School of Medical Sciences, Nagoya, - - 2014
Extracorporeal shock wave lithotripsy is the first-line therapy for large pancreatic duct stones; however, it requires a long duration of therapy. To clarify the effect of pancreatic stenting prior to extracorporeal shock wave lithotripsy on shortening the duration of therapy and reducing complications. We retrospectively compared 45 patients who underwent ...
Rizvi Asad A AA Hartford Cardiac Lab, Hartford Hospital/University of Connecticut School of Medicine, 80 Seymour Street, Hartford, CT, 06102-5037, - - 2014
Ever since the observation was made linking a higher prevalence of a patent foramen ovale (PFO) in younger individuals with cryptogenic stroke (CS), there has been a vigorous debate as to the role the PFO plays and a search for the optimal management strategy to prevent recurrent CS. Data from ...
Iino Yukiko Y Department of Otolaryngology, Jichi Medical University Saitama Medical Center , Saitama , - - 2014
Abstract Conclusions: Eosinophil cationic protein (ECP) concentrations in middle ear effusion (MEE) in patients with eosinophilic otitis media (EOM) were significantly decreased at 3 months after the administration of omalizumab from the baseline level (p < 0.05). This study provides new evidence that omalizumab reduces eosinophilic inflammation in the middle ...
Wang Sizhen S Medical School of Nanjing University, Research Institute of General Surgery, Jinling Hospital Nanjing 210002 - - 2014
ABSTRACT Background: Fluid therapy may be one of the most controversial topics in perioperative management. However, data concerning the influence of perioperative fluid administration on complications after pancreaticoduodenectomy are sparse. Methods: A group of 147 patients underwent pancreaticoduodenectomy for benign or malignant pathology of the pancreas or the periampullary region ...
Looi Khang-Li KL Papworth Hospital NHS Foundation Trust, , Cambridge, - - 2014
Studies have shown beneficial effects of cardiac resynchronisation therapy (CRT) on mortality among patients with heart failure. However the incremental benefits in survival from CRT with a defibrillator (CRT-D) are unclear. The choice of appropriate device remains unanswered. This is a single-centre observational study in a tertiary cardiac centre. Patients ...
Mutoh Tatsushi T From the Department of Surgical Neurology, Research Institute for Brain and Blood Vessels-AKITA, Akita, Japan (T.M., A.S., T.I.); Department of Neurosurgery, Teine Keijinkai Hospital, Sapporo, Japan (K.K.); Department of Nuclear Medicine and Radiology, Institute of Development, Aging and Cancer, Tohoku University, Sendai, Japan (T.M., Y.T.); and Department of Neurosurgery, Hokkaido University Graduate School of Medicine, Sapporo, Japan (K.K., - - 2014
The results of previous studies suggest that early goal-directed fluid therapy (EGDT) reduces delayed cerebral ischemia (DCI) after aneurysmal subarachnoid hemorrhage, but the effects of EGDT on clinical outcomes are still unclear. This study aimed to determine whether EGDT improves outcomes compared with standard less-invasive hemodynamic therapy. This study included ...
Levy Gerald D GD From the Southern California Permanente Medical Group, and Kaiser Permanente, Pharmacy Analytical Services, Downey, California, - - 2014
To evaluate the association between hyperuricemia and renal disease progression in a real-world, large observational database study. We conducted a population-based retrospective cohort study identifying 111,992 patients with hyperuricemia (> 7 mg/dl) from a large medical group. The final cohort were ≥ 18 years old, urate-lowering therapy (ULT)-naïve, and had ...
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