Search Results
Results 451 - 500 of 4821
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Kahloon Arslan A Department of Internal Medicine, University of Tennessee College of Medicine, Chattanooga, 979 East Third Street, Suite C-825, Chattanooga, TN, 37403, USA, - - 2014
Gastric variceal bleeding is associated with significant morbidity and mortality and limited endoscopic therapeutic options. The aim of this study was to evaluate the short- and long-term efficacy and safety of endoscopic therapy with 2-octyl-cyanoacrylate in patients with gastric variceal bleeding. A single-center retrospective review of patients receiving endoscopic therapy ...
Baros Duka Ninković - - 2014
Psoriasis is a chronic, inflammatory, immune-mediated skin disease. In addition to standard therapeutic modalities (antibiotics, cytostatics, phototherapy, photochemotherapy and retinoids), nonstandard methods can be used in the treatment of psoriasis. This includes balneotherapy which is most commonly used in combination with therapeutic resources. The aim of this research was to ...
Nammas Wail W Heart Center, Turku University Hospital and University of Turku , Turku , - - 2014
Abstract Background. The FinPAC trial showed that the strategy of uninterrupted oral anticoagulation (OAC) was non-inferior to interrupted OAC for the primary outcome of bleeding and thromboembolic complications in patients undergoing cardiac rhythm management device (CRMD) implantation. Methods. We conducted a post hoc analysis of the FinPAC data to explore ...
Jones Douglas W DW Vascular and Endovascular Surgery, New York Presbyterian Hospital - Weill-Cornell Medical Center, New York, NY, - - 2014
After endovascular therapy, duplex ultrasound surveillance to detect restenosis guides clinical decisions and defines treatment failure. However, the correlation between duplex ultrasound and symptom recurrence remains unclear. We reviewed our institutional experience (2007-2010) to identify patients undergoing endovascular therapy for claudication. The association between post-intervention systolic velocity ratio and patient-reported ...
Kido Larissa Akemi LA Department of Structural and Functional Biology, Institute of Biology, State University of Campinas (UNICAMP), Campinas, São Paulo, - - 2014
The aim of this study was to evaluate the structural and molecular effects of antiangiogenic therapies and finasteride on the ventral prostate of senile mice. 90 male FVB mice were divided into: Young (18weeks old) and Senile (52weeks old) groups; Finasteride group: Finasteride (20mg/kg); SU5416 group: SU5416 (6mg/kg); TNP-470 group: ...
Cerezo-Manchado Juan Jose JJ Hospital Universitario Morales Meseguer & Centro Regional de Hemodonacion, University of Murcia, Ronda de Garay s/n, 30003, IMIB, Murcia, - - 2014
Aim: To analyze VKORC1, CYP2C9 and CYP4F2 polymorphisms in relation to the main outcomes in the first stages of acenocoumarol therapy. Patients & methods: Nine hundred and forty one patients who had started therapy and in whom time to stable dosage, time to over-anticoagulation and adverse events occurred during 3 ...
Gupta Prashant P Department of Oral Medicine and Radiology, Peoples University, Bhopal, Madhya Pradesh, - - 2014
The study was designed to evaluate the serum interleukin-8 (IL-8) levels in patients with recurrent aphthous ulcer (RAU) and monitor the immunomodulation and altered IL-8 levels by levamisole before therapy and after levamisole therapy. This study was carried as a randomized case-control study involving a study group of 30 patients ...
Min Yang Won YW Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, - - 2014
The occurrence of gastroesophageal reflux disease (GERD) is known to be associated with lower post-treatment lower esoph-ageal sphincter pressure in patients with achalasia. This study aimed to elucidate whether GERD after pneumatic balloon dilata-tion (PD) has a prognostic role and to investigate how the clinical course of GERD is. A ...
Gompelmann Daniela D Pneumology and Critical Care Medicine, Thoraxklinik, University of Heidelberg, and Translational Research Center Heidelberg, Member of the German Center for Lung Research, Heidelberg, - - 2014
Background: Patients who achieve significant target lobe volume reduction (TLVR) following endobronchial valve (EBV) treatment may experience substantial improvements in clinical outcome measures. However, in cases of rapid TLVR, the risk of pneumothorax increases due to parenchymal rupture of the adjacent untreated lobe. Target lobe collapse may be more likely ...
van Zeller Mafalda M Drs van Zeller and Almeida and Ms Eusébio are affiliated with the Department of Pulmonology, Centro Hospitalar de São João, Porto, - - 2014
Treatment adherence is widely recognized as a critical problem in long-term oxygen therapy, particularly in ambulatory liquid oxygen (LOX) systems. Adherence-monitoring strategies may be helpful in managing patients. We evaluated subjects' adherence to LOX using VisionOx and compared these results with the subjects' own adherence diaries and self-reported perceptions of ...
Zeisberg A A Department of Ophthalmology, Charité University Medicine Berlin, Campus Benjamin Franklin, 12200, Berlin, - - 2014
The aim of this retrospective study was to determine the efficacy of proton beam irradiation in choroidal hemangioma in a long-term follow-up. A total dose of 20 Cobalt Gray equivalent (CGE) was administered to 50 eyes of 50 patients from September 1998 to September 2010. All treated patients presented with ...
Yeon Gyu-Min GM 1 Department of Pediatrics, College of Medicine, Kosin University , Busan, - - 2014
Abstract Objective: Few studies have been conducted among pediatric patients to examine clinical outcomes associated with the combined use of Oriental medicine and other therapies to treat epilepsy. The purpose of this study was to examine the clinical and laboratory characteristics of children with epilepsy being treated with traditional Korean ...
Varkonyi Istvan I Kenezy Gyula Hospital and Outpatient Facility, Debrecen, - - 2014
We completed a prospective study of 164 patients involved in a Clostridium difficile surveillance program, evaluating a range of variables such as disease severity, treatment regimen, and known clinical risk factors, for their effect on case lethality. The aim of this study was to determine if there are any additional ...
Yang Na Rae NR Department of Neurosurgery, Ewha Womans University School of Medicine, Mokdong Hospital, 911-1 Mok-dong, Yangcheon-gu, Seoul, 158-710, - - 2014
Problems that the risk of using antiplatelet/anticoagulant may overwhelm its benefits have been raised. We analyzed patients with spontaneous intracerebral hemorrhage who had received antiplatelet/anticoagulant therapy. A consecutive series of patients with spontaneous intracerebral hemorrhage who underwent brain computed tomographic (CT) scans within 48 h from attack. We analyzed the clinical ...
Song Gi-Won GW 1 Division of Liver Transplantation and Hepatobiliary Surgery, Department of Surgery, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea. 2 Address correspondence to: Sung-Gyu Lee, M.D., F.A.C.S., 388-1 Pungnab2-dong, Songpa-gu, Seoul, - - 2014
The use of rituximab (Rit) to prevent antibody-mediated rejection (AMR) of ABO-incompatible (ABOi) adult living donor liver transplants (ALDLTs) has raised questions about the role of local graft infusion therapy (LGIT) and splenectomy (SPN); however, they are still regarded as essential components of the desensitization (DSZ) protocol. The DSZ protocol ...
Flury Baharak Babouee - - 2014
Vertebral osteomyelitis (VO) may lead to disabling neurologic complications. Little evidence exists on optimal antibiotic management. All patients with primary, non-implant VO, admitted from 2000-2010 were retrospectively analyzed. Patients with endocarditis, immunodeficiency, vertebral implants and surgical site infection following spine surgery were excluded. Persistence of clinical or laboratory signs of ...
Mizobe Michio M Department of Cardiovascular Medicine, Graduate School of Medical Sciences, Kumamoto University, Kumamoto, - - 2014
The aim of this study was to examine the impact of CYP2C19 genotype on clinical outcome in coronary artery disease (CAD) patients with or without diabetes mellitus (DM). CYP2C19 polymorphism and DM are associated with increased risk of cardiovascular events during antiplatelet therapy following stent implantation. Platelet reactivity during clopidogrel ...
Kanji Hussein D HD Department of Critical Care Medicine, University of British Columbia; Faculty of Medicine, University of British Columbia, Vancouver, British Columbia, - - 2014
The purpose of the study was to compare the effect of limited echocardiography (LE)-guided therapy to standard management on 28-day mortality, intravenous fluid prescription, and inotropic dosing following early resuscitation for shock. Two hundred twenty critically ill patients with undifferentiated shock from a quaternary intensive care unit were included in ...
Morgan C Ll CL Global Epidemiology, Pharmatelligence, Cardiff, - - 2014
To compare the risk of major adverse cardiovascular events (MACE) and mortality for combination therapies with metformin and either sulfonylurea (SU) or DPP-4 inhibitor (DPP-4i). Data were from the UK Clinical Practice Research Datalink (CPRD). Patients with type 2 diabetes were selected if initiated with combination therapies comprising metformin plus ...
Cahn Pedro P Clinical Research Department, Fundación Huésped, Buenos Aires, Argentina. Electronic address: - - 2014
Daily oral triple therapy is effective at halting HIV disease progression, but can have toxic effects and is costly. We investigated whether dual therapy with lopinavir and ritonavir plus lamivudine is non-inferior to standard triple therapy. The GARDEL study (Global AntiRetroviral Design Encompassing Lopinavir/r and Lamivudine vs LPV/r based standard ...
Schroeder A S AS Department of Paediatric Neurology and Developmental Medicine, Hauner Children's Hospital, University of Munich, Germany; German Center for Vertigo and Balance Disorders, IFB(LMU), University of Munich, Germany. Electronic address: - - 2014
Robot-enhanced therapies are increasingly being used to improve gross motor performance in patients with cerebral palsy. To evaluate gross motor function, activity and participation in patients with bilateral spastic cerebral palsy (BS-CP) after Robot-enhanced repetitive treadmill therapy (ROBERT) in a prospective, controlled cohort study. Participants trained for 30-60 min in each of ...
Chon Min Ku MK Division of Cardiology, Department of Internal Medicine, Pusan National University Yangsan Hospital, Yangsan, - - 2014
Pulmonary thromboembolism (PTE) is a common clinical condition related to significant mortality. Furthermore, patients with PTE presenting with right heart thrombus show higher mortality due to rapid hemodynamic deterioration. But the optimal treatment of massive PTE is controversial although various methods have been developed and improved. Here, we presented a ...
Sulz Michael C MC Department of Gastroenterology and Hepatology, Kantonspital St. Gallen, - - 2014
Hemospray (Cook Medical, Winston-Salem, North Carolina, USA) is a hemostatic agent recently introduced for the management of upper gastrointestinal bleeding (GIB). To date, there is little experience with this fairly new hemostatic tool. The aim of this case series was to reflect the use and effectiveness of Hemospray as a ...
Aoki Jiro J Division of Cardiology, Mitsui Memorial Hospital, Tokyo, Japan. Electronic address: - - 2014
The endothelial progenitor cell (EPC) plays an important role in repairing vascular injury. Statins and angiotensin II receptor blockers increase the level of circulating EPCs. However, it is unknown whether the angiotensin II receptor blocker olmesartan synergistically acts with statins to increase the levels of circulating EPCs. Moreover, the association ...
Vinayagam S S Katharine Dormandy Haemophilia Centre & Thrombosis Unit, Royal Free London NHS Foundation Trust, London, United - - 2014
Haemostatic management of surgery in patients with von Willebrand disease (VWD) includes DDAVP(®) or von Willebrand factor (VWF)-containing concentrates. Although the recommendations are for monitoring by VWF activity assays, it is quite common for clinicians to use factor VIII due usually to longer turnaround times required for VWF ristocetin cofactor ...
Kurita Takashi T Division of Rheumatology, Endocrinology and Nephrology, Hokkaido University Graduate School of Medicine and Translational Research and Clinical Trial Center, Hokkaido University Hospital, Sapporo, - - 2014
Objective. Interstitial lung diseases (ILDs) complicated with PM or DM are frequently aggressive and refractory to treatment. Recently some reports have suggested the potential benefit of tacrolimus for severe ILD complicated with PM/DM. However, little evidence has yet shown the efficacy of tacrolimus in these settings. The aim of this ...
Stucky C-C H CC Department of General Surgery, Mayo Clinic Arizona, 5777 E. Mayo Boulevard, Phoenix, AZ, 85054, - - 2014
Previous reports document the safety of open inguinal herniorrhaphy in patients on chronic warfarin therapy; however, the practice remains controversial. This study is a 10-year update of our experience. A retrospective review of 1,839 consecutive patients undergoing open inguinal hernia repair was conducted from 2000 to 2010. All patients on ...
Hernández Domingo - - 2014
Left ventricular hypertrophy (LVH) is common in kidney transplant (KT) recipients. LVH is associated with a worse outcome, though m-TOR therapy may help to revert this complication. We therefore conducted a longitudinal study to assess morphological and functional echocardiographic changes after conversion from CNI to m-TOR inhibitor drugs in nondiabetic ...
Liang Zhihui Z Department of Radiology, Bethune International Peace Hospital, Zhongshan West Road 398, Shijiazhuang, 050082, Hebei, - - 2014
To evaluate the role of filter implantation in reducing the incidence of fatal pulmonary embolism during the endovascular treatment of thrombosis in the major tributary of the superior vena cava (SVC). From October 2004 to October 2008, we conducted a cohort study of 40 patients with thrombosis of the central ...
Stabile Eugenio E Department of Advanced Biomedical Sciences, University of Napoli "Federico II", Napoli, Italy. Electronic address: - - 2014
Common clinical practice recommends dual antiplatelet therapy (DAPT) for transcatheter aortic valve implantation (TAVI). The aim of the study was to evaluate, in a double blind randomized study, the safety of TAVI, with adjunctive pharmacotherapy consisting of single antiplatelet therapy. From April 2010 to April 2011, 120 consecutive patients, undergoing ...
Westendorp Willeke F - - 2014
Stroke is a leading cause of death worldwide. Infections after stroke occur in 30% of stroke patients and are strongly associated with unfavourable outcome. Preventive antibiotic therapy lowers infection rate in patients after stroke, however, the effect of preventive antibiotic treatment on functional outcome after stroke has not yet been ...
Steinberg Benjamin A BA Duke Center for Atrial Fibrillation, Durham, NC, - - 2014
Atrial fibrillation (AF) and coronary artery disease (CAD) are common in older patients. We aimed to describe the use of antiarrhythmic drug (AAD) therapy and clinical outcomes in these patients.METHODS AND RESULTS: We analysed AAD therapy and outcomes in 1738 older patients (age ≥65) with AF and CAD in the ...
Nishida Tsutomu T Tsutomu Nishida, Masahiko Tsujii, Hideki Iijima, Tetsuo Takehara, Department of Gastroenterology and Hepatology, Osaka University Graduate School of Medicine, Suita, Osaka 565-0871, - - 2014
To evaluate the efficacy and safety of esomeprazole-based triple therapy compared with lansoprazole therapy as first-line eradication therapy for patients with Helicobacter pylori (H. pylori) in usual post-marketing use in Japan, where the clarithromycin (CAM) resistance rate is 30%. For this multicenter, randomized, open-label, non-inferiority trial, we recruited patients (≥ ...
Liu Chen-Hua CH Department of Internal Medicine, National Taiwan University Hospital, , Taipei, - - 2014
Data comparing the efficacy and safety of combination therapy with peginterferon plus low-dose ribavirin and peginterferon monotherapy in treatment-naive haemodialysis patients with hepatitis C virus genotype 2 (HCV-2) infection are limited. In this randomised trial, 172 patients received 24 weeks of peginterferon alfa-2a 135 μg/week plus ribavirin 200 mg/day (n=86) ...
Shi Yongjun Y Department of Gastroenterology, Provincial Hospital Affiliated to Shandong University, 324 Jingwu Weiqi Road, Jinan, 250021, Shandong, People's Republic of China, - - 2014
Transjugular intrahepatic portosystemic shunt (TIPS) with adjunctive embolotherapy has recently been reported to be effective in the prevention of variceal hemorrhage of cirrhotic patients. However, further investigation of its long-term efficacy is still needed. To examine the rebleeding, survival, and hepatic encephalopathy (HE) after treatment with TIPS alone and TIPS ...
Yang Ten-Fang TF Institute of Bioinformatics and Systems Biology, National Chiao Tung University, Hsinchu, Taiwan; Graduate Institute of Biomedical Informatics, Taipei Medical University and Evidence Based Medicine Center, Taipei Medical University Hospital, Taipei, - - 2014
The aim of our study was to determine whether pre-emptive statin therapy was associated with improved outcome of infective endocarditis (IE). We conducted a nationwide, population-based, propensity score-matched cohort study with the Taiwan's National Health Insurance Research Database. All patients with IE between January 2000 and December 2010 were enrolled. ...
Haanschoten Marco C MC Department of Anesthesiology, Intensive Care Unit, Catharina Hospital, Eindhoven, The Netherlands; Intensive Care Unit, Catharina Hospital, Eindhoven, The - - 2014
In the present study, we investigated the survival of patients who received postoperative renal replacement therapy (RRT) after cardiac surgery. We specifically focused on factors predicting long-term outcome in elderly patients. Data of all patients that received unintentional renal replacement therapy following cardiac surgery between 2004 and 2010 were analyzed. ...
Sheu Jiunn-Jye - - 2014
We tested the hypothesis that clopidogrel and cilostazol combination therapy could effectively attenuate systemic inflammatory reaction, facilitate proliferation of circulating endothelial progenitor cell (EPC), and improve the clinical outcomes of critical limb ischemia (CLI) in patients unsuitable for surgical revascularization or percutaneous transluminal angioplasty (PTA). A total 55 patients (mean ...
Farkas Klaudia K First Department of Medicine, University of Szeged, 8-10 Koranyi fasor, Szeged, H6720, - - 2014
To date, corticosteroids have been the primary therapies for acute, severe ulcerative colitis (UC). Patients not responding to intravenous steroids assessed at 3-5 days of the treatment are candidates for second-line rescue therapy. Cyclosporine (CsA), tacrolimus and infliximab (IFX) are also effective therapeutic options in acute, severe UC. In this ...
Alpak Gokay G Department of Psychiatry, Gaziantep University, School of Medicine, Gaziantep, - - 2014
Objective: To investigate the effects of recurrent electroconvulsive therapy (ECT) on cardiac function as assessed by echocardiography. Subjects and Methods: Twenty-three patients (11 males and 12 females) with different psychiatric disorders who were apparently free of any cardiovascular disorders and underwent ECT were enrolled in the study. Echocardiographic findings including ...
Warshauer Jeremy J VA North Texas Healthcare System and University of Texas Southwestern Medical Center, Dallas, Texas, - - 2014
Background: Preoperative bridging with a glycoprotein IIb/IIIa inhibitor is often performed in patients with prior coronary stents undergoing surgery who require antiplatelet therapy discontinuation, but its safety and efficacy have received limited study. We performed a weighted meta-analysis of the outcomes in patients with coronary stents undergoing bridging with glycoprotein ...
Kim Na Young NY Department of Anesthesiology and Pain Medicine, Yonsei University College of - - 2014
Background: Preoperative fibrinogen concentration is associated with increased blood loss at the lower end, and with hypercoagulability-related ischemic event at the higher end in cardiac patients. We evaluated the influence of preoperative fibrinogen concentration on blood loss and outcome in patients who received clopidogrel in proximity to off-pump coronary artery bypass ...
Foo Hong H Department of Microbiology and Infectious Diseases, Sydney South West Pathology Service, Liverpool, Sydney, NSW, - - 2014
Enterococci are an important cause of nosocomial and community-acquired infections, with bacteraemia being one of the most common presentations. Although inappropriate antimicrobial therapy has been associated with poorer outcomes in Enterococcus faecalis (EF) bacteraemia, the impact of antimicrobial choice, namely β-lactam versus glycopeptide therapy, has not been well described. We ...
Hirano Daisaku D Department of Urology, Higashi-matsuyama City Municipal Hospital , Higashi-matsuyama Saitama-ken , - - 2014
Abstract Objective. The aim of this study was to prospectively verify the relationship between the clinical efficacies of secondary hormone therapy for castration-resistant prostate cancer (CRPC) following first line hormone therapy and neuroendocrine differentiation (NED). Material and methods. Forty-six consecutive patients with CRPC following first line hormone therapy who were ...
Iba Toshiaki - - 2014
The severity of sepsis increases along with the degree of coagulation disorder, and a fulminant coagulation abnormality is recognized as disseminated intravascular coagulation (DIC). The mortality of sepsis-associated DIC remains as high as 40%, which is comparable to that of septic shock. Even though intensive research is ongoing, no established ...
Gonzalez-Serna Alejandro A BC Centre for Excellence on HIV/AIDS, Vancouver V6Z1Y6, BC, - - 2014
The aim of this study was to describe the rates and predictors of discontinuing first-line antiretroviral therapy in the different eras of treatment over a nearly 20 year period initiated in British Columbia between 1992 and 2010. All naive adults who started antiretroviral therapy (first-line antiretroviral therapy) at any hospital ...
Ticly Flavia G FG Department of Ophthalmology, University of Campinas (UNICAMP) , Campinas, São Paulo, Brazil - - 2014
Abstract Purpose: To determine the efficacy of topical ketorolac tromethamine in preventing cystoid macular edema (CME) after uncomplicated cataract surgery. Method: This single-center, prospective, double-masked, randomized clinical trial consisted of 81 patients who were scheduled for cataract surgery. Patients were randomized to receive hypromellose/dextran 70 as a placebo (n=44) or ...
van Dussen Laura - - 2014
To evaluate the cost-effectiveness of enzyme replacement therapy (ERT) compared to standard medical care without ERT in the Dutch cohort of patients with type 1 Gaucher disease (GD I). Cost-effectiveness analysis was performed using a life-time state-transition model of the disease's natural course. Transition probabilities, effectiveness data and costs were ...
Lee Minkyung M Gangnam Severance Hospital, Yosei University College of Medicine, Department of Nuclear Medicine, 211 Eonju-Ro, Gangnam-Gu, Seoul, Korea, Republic of, 135-720, +82-2-2019-3742 ; - - 2014
Abstract Background Most current guidelines suggest 1 or 2 weeks of low iodine diet (LID) before radioactive iodine ablation therapy (RAIT) to increase its efficacy in differentiated thyroid cancer (DTC) patients after total thyroidectomy. LID duration is particularly important for patients living in iodine excess areas. However, there is no ...
Shim Jae-Jun JJ Department of Internal Medicine, Kyung Hee University School of Medicine, Seoul, - - 2014
Analysis of alpha-fetoprotein (AFP) levels affords limited diagnostic accuracy because of the high false-positive rates, especially in those with active chronic hepatitis B (CHB). We measured AFP levels before and after commencement of oral antiviral therapy and explored the utility of these data in terms of early detection of hepatocellular ...
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