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Results 351 - 400 of 1800
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Le Loët Xavier - - 2011
Objectives. To test the performances of combining anti-CCP second generation (CCP2) with ACR 1987 classification criteria and to diagnose early RA in a community-based very early arthritis (VErA) patient cohort. Methods. The VErA cohort comprised 310 patients (median age 52 years; 68.1% women; median symptom duration 4.2 months; glucocorticoid- and ...
Kobayashi Tatsuya - - 2011
Thirty-eight patients diagnosed with osteoarthritis underwent 41 cruciate-retaining total knee arthroplasties. In varus and valgus tests at flexion, subjects were seated on a table at 80° of knee flexion; 50 N was applied perpendicular to the lower leg. The factors affecting the postoperative flexion angle were investigated in a multiregression ...
Radzimski Andy Oliver - - 2011
CONTEXT: Footwear modifications have been investigated as conservative interventions to decrease peak external knee adduction moment (EKAM) and pain associated with knee osteoarthritis (OA). OBJECTIVE: To evaluate the literature on the effect of different footwear and orthotics on the peak EKAM during walking and/or running. METHODS: A systematic search of ...
Waton A - - 2011
The purpose of this study was to investigate the effects of right leg restriction at the knee, ankle or both, on a driver's braking times. Previous studies have not investigated the effects of knee restriction on braking performance. A total of 23 healthy drivers performed a series of emergency braking ...
Zhao Ling - - 2011
Objective: To study the effects of three different laser treatments (650 nm alone, 10.6 μm alone and combined laser of 650 nm and 10.6 μm) on experimental osteoarthritis of the knees in C57 black mice. Methods: Sixty C57 black mice were divided randomly into 6 groups. Ten mice were assigned ...
Ouyang Ba-Si - - 2011
To observe the effect of electro-acupuncture (EA) on tumor necrosis factor-α (TNF-α) and vascular endothelial growth factor (VEGF) in peripheral blood and joint synovia in patients with rheumatoid arthritis (RA) to verify the clinical efficacy of EA. Adopting randomized controlled principle, the 63 RA patients enrolled were assigned to two ...
Ward T R - - 2011
Bicruciate-stabilised total knee replacement (TKR) aims to restore normal kinematics by replicating the function of both cruciate ligaments. We performed a prospective, randomised controlled trial in which bicruciate- and posterior-stabilised TKRs were implanted in 13 and 15 osteo-arthritic knees, respectively. The mean age of the bicruciate-stabilised group was 63.9 years ...
Vijayakumar Krishna Pillai - - 2011
The association of the present Chikungunya pandemic with a mutation in the Chik virus is already established in many parts of the world, including Kerala. Kerala was one of the worst-affected states of India in the Chikungunya epidemic of 2006-2007. It is important to discuss the clinical features of patients ...
Hsu Chi-Hsiang - - 2011
The purpose of this study was to evaluate the clinical outcome of total knee arthroplasty and analyze the prognostic factors in patients with stiff knees. Thirty-two patients (39 knees) with severe knee arthritis and an arc of motion of 50° or less were treated by total knee arthroplasty. The mean ...
Coenen Michaela - - 2011
PURPOSE: To compare two different approaches to performing focus groups and individual interviews, an open approach, and an approach based on the International Classification of Functioning, Disability and Health (ICF). METHODS: Patients with rheumatoid arthritis attended focus groups (n = 49) and individual interviews (n = 21). Time, number of concepts, ICF categories identified, ...
Koyama Yoshinobu - - 2011
Although etanercept (ETN) is effective when used in monotherapy for the treatment of rheumatoid arthritis (RA), ETN/methotrexate (MTX) combination therapy is more efficacious. However, some patients show MTX intolerance; these patients may develop adverse events (AEs) or have risk factors for AEs. There is limited published information regarding the efficacy ...
Silkman Carrie - - 2011
Strength deficits of the musculature surrounding the knee can be significant after anterior cruciate ligament reconstruction (ACLr). In patients who have undergone ACLr, regaining quadriceps function is a core focus of therapeutic rehabilitation. Knee stability, which is dependent on neuromuscular control, including quadriceps strength, is necessary for normal coordination of ...
Yusuf E - - 2011
OBJECTIVE: To investigate in which way body mass index (BMI) and alignment affect the risk for knee osteoarthritis (OA) progression. METHODS: Radiographs of 181 knees from 155 patients (85% female, mean age 60 years) with radiographic signs of OA were analyzed at baseline and after 6 years. Progression was defined ...
Finnegan Sorcha S Centre for Infection and Immunity, Queen's University Belfast, Belfast, UK. - - 2011
Juvenile idiopathic arthritis (JIA) consists of a heterogeneous group of inflammatory disorders, within which there are a number of clinical subgroups. Diagnosis and assignment to a particular subgroup can be problematical and more concise methods of subgroup classification are required. This study of the synovial membrane characterises the immunohistochemical features ...
Becher Christoph - - 2011
INTRODUCTION: The purpose of this study was to evaluate the results of a contoured focal articular femoral condyle resurfacing prosthetic in the treatment of full-thickness cartilage and osteochondral defects at the medial femoral condyle of the knee beyond 5 years. METHODS: In a multicenter case series, preoperative and follow-up scores of ...
Curtiss Heather M - - 2011
To evaluate the accuracy of ultrasound (US)-guided and palpation-guided knee injections by an experienced and a less-experienced clinician with use of a superolateral approach. Single-blinded, prospective study. Academic institution procedural skills laboratory. Twenty cadaveric knee specimens without trauma, surgery, or major deformity. US-guided and palpation-guided knee injections of colored liquid ...
Xiong Min - - 2011
Abstract Conclusion. The average recovery of hearing and cessation of tinnitus was significantly better after treatment with Radix Astragali (RA) than after non-treatment with RA. RA can be valuable adjuvant therapy for patients with acute acoustic trauma (AAT). Objectives. AAT is one of the early indications for the use of ...
Kazam Jonathan K - - 2011
Objectives- The purpose of this study was to investigate whether routine clinical sonographic evaluation of femoral trochlear cartilage can identify abnormalities in patients with knee pain. Methods- Short-axis sonograms of the femoral trochlear cartilage were obtained from 20 symptomatic knees in 20 consecutive patients (16 women and 4 men; mean ...
Johnson Timothy S - - 2011
Our objective was to assess the accuracy rate of needle placement with the anterosuperior technique of glenohumeral joint injection that uses familiar palpable superficial landmarks as a guide instead of diagnostic imaging. Between April 2007 and October 2007 at our institution, 42 patients met the study inclusion criteria of being ...
Woo Young Kyun - - 2011
Total knee arthroplasty (TKA) using a cemented technique has been recommended in patients with rheumatoid arthritis owing to the initial stability of the fixation and long-term durability of the components; however, similar long-term follow-up results have been reported in patients who have undergone cementless TKA. The purpose of this study ...
Güler-Yüksel M - - 2011
OBJECTIVE: /st> To study the association between metacarpal bone mineral density (BMD) loss and progressive hand osteoarthritis (OA) over 2 years. METHODS: /st> Using the Kellgren-Lawrence (KL) grading scale and the Osteoarthritis Research Society International Atlas, standardised hand radiographs of 181 patients with primary OA at multiple sites (mean age ...
Takahashi Kenji - - 2011
BACKGROUND: The clinical evidence of the efficacy of hyperthermia on osteoarthritis (OA) has not yet been clearly established. In addition, the application of a modality that can control the temperature inside the joints has not been reported. The purpose of this study was to investigate the effect of percutaneous radiofrequency ...
Rojas-Serrano Jorge - - 2011
The purpose of this study is to determine factors associated with a non-ACR 50 response at 6 months of follow-up, in a cohort of patients with early rheumatoid arthritis (RA). Early RA patients (symptom duration <1 year), treated with the same combination treatment (methotrexate and sulfasalazine), were included. Demographic characteristics of the ...
Mouzopoulos George - - 2011
PURPOSE: The aim of this study was to perform a review of the management of patellar cartilage defects, identify prognostic factors for better clinical outcomes, and propose a treatment algorithm of this challenging entity. METHODS: We conducted a review of multiple databases, evaluating the clinical outcomes after patellar cartilage lesion ...
Oshima Yasushi - - 2011
OBJECTIVE: The objective of this study was to evaluate whether light-emitting diodes (LEDs) could be effective in a noninvasive, therapeutic device for the treatment of osteoarthritic (OA) knee joints. DESIGN: Five weeks following the anterior cruciate ligament transection (ACLT) of mature New Zealand White rabbits, the animal knees were exposed ...
Jamal Shahin - - 2011
OBJECTIVE: To determine the proportion of patients with rheumatoid arthritis (RA) seen by rheumatologists and treated with disease-modifying antirheumatic drugs (DMARD) within 3 months of symptom onset, to determine where treatment delays occur, and to identify contributing factors. METHODS: A retrospective cohort study in which adult patients with RA, diagnosed ...
Kameda Hideto - - 2011
OBJECTIVE: The aim of the Efficacy and Safety of Etanercept on Active Rheumatoid Arthritis Despite Methotrexate Therapy in Japan (JESMR) study is to compare the efficacy of continuation versus discontinuation of methotrexate (MTX) when starting etanercept (ETN) in patients with active rheumatoid arthritis (RA). METHODS: In total, 151 patients with ...
Markenson Joseph A - - 2011
To evaluate persistence with anti-tumor necrosis factor (TNF) therapy and predictors of discontinuation in patients with rheumatoid arthritis (RA). This retrospective analysis used data from RADIUS 1, a 5-year observational registry of patients with RA, to determine time to first- and second-course discontinuation of etanercept, infliximab, and adalimumab. First-course therapy ...
Li Xueping - - 2011
We evaluated the effect of low-intensity pulsed ultrasound (LIPUS) on MMP-13 and MAPKs expression in rabbit knee osteoarthritis (OA). For this purpose, 18 New Zealand white rabbits were randomly and equally divided into O + L, O - L, and SO groups. In O + L group, animals underwent right back leg ACLT operation and LIPUS ...
Verkleij S P J - - 2011
OBJECTIVE: To identify sources of heterogeneity (statistical, methodological, and clinical) in studies evaluating non-steroidal anti-inflammatory drugs (NSAIDs) vs acetaminophen in patients with knee and hip osteoarthritis (OA) to elucidate variations in outcomes. METHOD: A database search (1966 to January 2010) was made for (randomized) controlled trials ((R)CTs) comparing NSAIDs vs ...
Albert A - - 2011
Isolated subtalar arthrodesis is the treatment of choice for several conditions -mostly subtalar arthritis, tarsal coalition and posterior tibial tendon dysfunction- unresponsive to conservative treatment. Arthroscopic procedures are an interesting recent alternative, less invasive than conventional open techniques. Posterior arthroscopy, in prone position, could be more advantageous than the conventional lateral and/or ...
Lanni Stefano - - 2011
Objectives. To investigate the efficacy of IA CS (IAC) therapy in single and multiple joints in children with JIA and to seek for predictors of synovitis flare. Methods. The clinical charts of patients who received their first IAC injection between January 2002 and December 2008 were reviewed. The CS used ...
Huang I-Yueh - - 2011
The aims of this preliminary study were to present a modified mandibular splint together with a treatment regimen and to evaluate their effects on the treatment of reciprocal joint sounds of the temporomandibular joint (TMJ). The study participants were recruited from 312 consecutive patients in the temporomandibular disorder clinic of ...
Lamontagne Mario - - 2011
Understanding how the function of the lower extremity joints during everyday movements following surgery to treat cam femoro-acetabular impingement is essential to assess whether surgical intervention effectively restores the normal biomechanics of the hip. The purpose of this study was to compare preoperative and postoperative lower-extremity joint and pelvic angular ...
Mann Jeffrey A - - 2011
There has been a resurgence of interest in total ankle replacement (TAR) due to improved results with newer prostheses. However, long-term survivorship data has been limited. The STAR™ Ankle prosthesis is the first three-part prosthesis approved for use in the United States. Eighty-four total ankle replacements were performed in 80 ...
Ramisetty N - - 2011
We performed a retrospective radiological audit of the hip resurfacings carried out in our trust over a five-year period. Abnormal cup inclination angle (CIA) and stem shaft angle (SSA) are recognised risk factors for revision in hip resurfacing. Our aims were to identify the CIA and SSA for hip resurfacings ...
Kivlan Benjamin R BR John G. Rangos Sr. School of Health Sciences, Duquesne University, Pittsburgh, Pennsylvania 15282, USA. - - 2011
The purpose of this study was to compare the percent relief from injection among subjects with arthroscopic findings of femoroacetabular impingement (FAI) and labral and chondral pathologies while controlling for coexisting extra-articular pathology. We retrospectively reviewed 72 consecutive subjects (54 female and 18 male subjects), aged 29.9 ± 10.4 years ...
Kuo Li-Lin - - 2011
Rationale, aims and objectives  To develop a short screening test for the detection of preclinical glaucoma. Method  This case-control study involved 690 participants aged 40 years or older: 338 patients with glaucoma or suspected glaucoma and 352 patients without glaucoma, who served as a control group. All participants were interviewed ...
Li Jian - - 2011
Our purpose was to assess the feasibility, safety, and effectiveness of a modified predilation for middle cerebral artery (MCA) stenosis. Wingspan stenting of MCA remains a technical challenge, and rates of residual stenosis and restenosis must be lowered. A series of 48 patients with symptomatic MCA stenosis greater than 50% ...
Nemec Scott A - - 2011
Primary midfoot arthritis is a disabling painful condition of the foot. The aim of the study was to assess the functional outcomes following midfoot arthrodesis for primary midfoot arthritis. Between 2000 and 2006, 95 patients (104 feet) underwent midfoot arthrodesis for primary midfoot arthritis. Midfoot collapse, if present, was corrected ...
Hassaballa Mo - - 2011
Accurate component alignment and joint line reproduction in total knee replacement (TKR) is crucial for successful clinical outcome. Advances in instrumentation and better understanding of the biomechanics can help to achieve better three dimensional alignments of TKR components and joint line restoration. We compared the accuracy of component alignment and ...
Bundhoo Shantu S - - 2011
Background: Limited data is available to guide operators as to the optimal revascularisation strategy in patients with previous CABG representing with angina. Method: Retrospective analysis of 161 patients with prior CABG undergoing PCI in two centres between September 2005 and April 2008. Results: 161 patients (132 male, 68 ± 8years) ...
Lindholt J S - - 2011
BACKGROUND: The aim of this study was to compare the mortality rate within 30 days of elective surgery for abdominal aortic aneurysm (AAA) in men randomized to an invitation for ultrasound screening with that of men in the control group, whose aneurysms were detected incidentally. METHODS: Relevant reports from randomized ...
Bertrand Olivier F - - 2011
Background: The use of routine aspiration thrombectomy in primary percutaneous coronary intervention (PCI) remains controversial. Methods: Patients in the EArly Discharge after Transradial Stenting of CoronarY Arteries in Acute Myocardial Infarction (n = 105) study were treated with aspirin, clopidogrel, and abciximab within 6 hr of symptoms onset. Operators were ...
Birkmeier K Anette - - 2011
Objectives and Background: First generation drug-eluting stents have shown differential efficacy in high-risk patient subsets at one year. It is unclear whether these differences endure over the medium- to long-term. We compared the five-year clinical efficacy and safety of sirolimus-eluting stents (SES) and paclitaxel-eluting stents (PES) in a population of ...
Yildiz Necmettin - - 2011
The aim of the study was to determine which vasoactive agent was more efficacious for erectile dysfunction (ED), intracavernosal papaverine or oral sildenafil, in paraplegic men within the first year after injury by using a penile color Doppler ultrasound as a quantitative imaging method and to determine the association between ...
Ajike S O - - 2011
Twenty-six patients (12 males and 14 females) between two days and 41 years old with temporomandibular joint ankylosis were retrospectively reviewed. Thirty-three joints were involved; 19 unilateral and six bilateral. The aetiologies were trauma, 69.2%; infection, 15.4%; unknown, 11.5% and congenital, 3.9. The majority, 31 were intracapsular while the remaining ...
Brown Christopher - - 2011
Postoperative or postinjury inflammation after knee surgery is a significant clinical challenge. Cytokines, particularly interleukin-1 (IL-1), released by inflammatory cells have been shown to have a role in cartilage homeostasis and tissue repair and fibrosis. Anakinra, an IL-1 receptor antagonist (IL-1ra), has shown promising results from its use in treating ...
Fjeldstad Cecilie - - 2011
To evaluate balance in women with multiple sclerosis (MS) who have low disability and minimal clinical impairments as measured by the Expanded Disability Status Scale (EDSS), and compare them with healthy age-matched controls. Patients were aged between 18 and 64 years; 67 individuals with MS (μ=44.0±1.2 years) and 45 healthy ...
von der Leyen Heiko E - - 2011
Abstract Neointimal hyperplasia causing recurrent stenosis is a limitation of the clinical utility of percutaneous transluminal coronary interventions (PCI). Nitric oxide (NO) inhibits smooth muscle cell proliferation, platelet activation, and inflammatory responses, all of which have been implicated in the pathogenesis of restenosis. In animals, neointimal proliferation after balloon injury ...
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