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Sasaki Junko - - 2012
We prospectively examined the additional effects of highly purified eicosapentaenoic acid (EPA) particularly on the vascular function of diabetic patients with hypercholesterolemia receiving statin therapy. We enrolled 28 patients with type 2 diabetes complicated by dyslipidemia who had been treated with statins for at least one year. The patients were ...
Girerd Nicolas - - 2012
BACKGROUND: Postoperative atrial fibrillation (POAF) is a frequent complication of coronary artery bypass grafting (CABG) surgery. The objective of this study was to determine the impact of POAF on both short- and long-term mortality following isolated CABG. HYPOTHESIS: POAF is associated with a poorer short and long-term mortality following CABG. ...
Rocco Andrea - - 2012
It is unclear if a certain lipid profile and/or statin use contribute to symptomatic intracerebral haemorrhage (sICH), poor outcome or mortality after intravenous thrombolysis for ischaemic stroke. The aim of the current study was to assess the impact of statin use and lipid profile on sICH, outcome and mortality following ...
Savvidou Christiana - - 2012
The purpose of this study is to identify a possible correlation between statin administration and incidence of spontaneous distal biceps tendon ruptures. We retrospectively reviewed 104 patients with distal biceps tendon rupture that were treated surgically from 2004 to 2010, 102 males and two females with mean age 47 years ...
Zare Mohammad - - 2012
Through a clinical trial we evaluated statin therapy benefits over stroke outcome. All patients with moderate stroke in Middle Cerebral Artery (MCA) were registered during February 2006 to February 2008, in Al Zahra Hospital, Isfahan, Iran. Among 55 patients who were enrolled in the present study, 25 subjects received 20 ...
Taitel Michael - - 2012
To evaluate the impact of a community-based pharmacist-led face-to-face counseling program on medication adherence for patients who were new to therapy (NTT) for statin medications. This retrospective cohort study evaluated a program that was implemented in 76 national community pharmacies located in the midwest USA. It consisted of two face-to-face ...
Toth Peter P - - 2012
The purpose of this research was to compare the effects of niacin extended-release in combination with simvastatin (NER/S) versus atorvastatin monotherapy on high-density lipoprotein (HDL) particle number and size in patients with hyperlipidemia or dyslipidemia from the SUPREME study. This was a post hoc analysis of patients (n = 137) ...
Hinz Jose - - 2012
Peri-operative statin therapy in cardiac surgery cases is reported to reduce the rate of mortality, stroke, postoperative atrial fibrillation, and systemic inflammation. Systemic inflammation could affect the hemodynamic parameters and stability. We set out to study the effect of statin therapy on perioperative hemodynamic parameters and its clinical outcome. In ...
Tenenbaum Alexander - - 2012
The effect of combination of fibrate with statin on major adverse cardiovascular events (MACE) following acute coronary syndrome (ACS) hospitalization is unclear. The main aim of this study was to investigate the 30-day rate of MACE in patients who participated in the nationwide ACS Israeli Surveys (ACSIS) and were treated ...
Reynolds Steven J - - 2012
Viral load monitoring (VLM) to identify individuals failing antiretroviral therapy (ART) is not widely available in resource-limited settings. We compared the genotypic resistance patterns between clients with VLM versus immunological monitoring (IM). Between 2004-2008, 559 ART naïve clients were enrolled in a prospective cohort, initiated on ART, and monitored with ...
Tycinska Agnieszka M - - 2011
To investigate the hypothesis that atorvastatin decreases blood pressure (BP) values and improves endothelial function assessed by flow-mediated dilation (FMD) in normolipidaemic hypertensive patients. Fifty-six hypertensive patients were randomized in a 2 : 1 proportion to atorvastatin (80 mg/day/3 months; group A; n = 39) or previous standard anti-hypertensive therapy ...
Athyros Vasilios G - - 2011
The short-term effects of multifactorial intervention for cardiovascular disease (CVD) prevention on renal function and serum uric acid (SUA) levels in patients with stage 3 chronic kidney disease (CKD) and multiple CVD risk factors are unclear. The aim of the study was to prospectively assess these effects. This post hoc ...
Toth Peter P - - 2012
Recent trends suggest a decreased use of ezetimibe/simvastatin combination and coadministered ezetimibe plus statin therapies. This analysis evaluated changes in prescription patterns for ezetimibe/simvastatin, ezetimibe plus statins, and statin therapies and expected effects on low-density lipoprotein cholesterol (LDL-C) lowering during 2007 to 2008. Prescription pattern changes were assessed by the ...
Euler Zelda - - 2012
We previously established that at 3 years postseroconversion, ~30% of HIV-infected individuals have cross-reactive neutralizing activity (CrNA) in their sera. Here we studied the kinetics with which CrNA develops and how these relate to the development of autologous neutralizing activity as well as viral escape and diversification. For this purpose, ...
Shekhar Pandey A - - 2011
When a standard dose of statins fails to achieve lipid control in patients at high risk for coronary artery disease (CAD), increasing the statin dosage or co-administration of additional agents is recommended. The aim of this study was to compare the safety and lipid-lowering efficacy of doubling the standard statin ...
Wang Mao Qiang - - 2011
Objective: To assess the feasibility and effectiveness of transjugular intrahepatic route aspiration thrombectomy and catheter-directed thrombolytic therapy in patients with acute superior mesenteric venous thrombosis. Materials and methods: During a period of 8 years, 12 patients with acute thrombosis of the superior mesenteric vein (SMV) were treated by transjugular intrahepatic approach. ...
Mohseni-Bod Hadi - - 2011
: To evaluate the accuracy of central venous oxygen saturation recordings from a new in-line pediatric oximetry catheter. : Prospective, observational study. : Eighteen pediatric patients who needed central venous access for monitoring and/or treatment between January 2006 and June 2006 in the pediatric intensive care unit of the Hospital ...
Tokgoz Bulent - - 2011
Aim. Peritonitis is currently one of the leading complications of continuous ambulatory peritoneal dialysis (CAPD) treatment. Aminoglycosides and vancomycin are used in the treatment of CAPD peritonitis despite their potential risk for ototoxicity. N-acetylcysteine (NAC) is a molecule used in the treatment and prophylaxis of many diseases related to oxidative ...
Ahn Joong Ho - - 2011
Abstract Conclusion: We suggest that cochlear implantation (CI) should be a good therapeutic modality for hearing restoration in patients with common cavity malformed ears. Objective: To analyze hearing improvement from CI performed in common cavity malformed cochleae. Methods: A total of 11 patients (5 male and 6 female, mean age ...
Skarzynski Henryk - - 2011
Abstract Conclusion: This study shows that by using the round window approach and deep insertion, it is possible to reduce electrode insertion trauma (EIT), as indicated by the results of the hearing preservation marker. Objectives: In this prospective study EIT was evaluated in 42 subjects with low frequency hearing before ...
Rutt Amy L - - 2011
Intratympanic (IT) steroids are often used to treat inner ear disorders such as sudden idiopathic sensorineural hearing loss, autoimmune inner ear disease, and Ménière disease. Administration of corticosteroids via IT injection, via application with a pledget to the round window, or via catheter has been used for this purpose. The ...
Liu S-C - - 2011
To investigate the necessity of routine application of hyperbaric oxygen therapy for sudden sensorineural hearing loss. DESIGN/SETTING AND PARTICIPANTS: A retrospective chart review looked at 465 patients, with 353 of them receiving pharmacologic treatments alone. Among these patients, 76 underwent systemic steroid treatment only (steroid group) and 277 received systemic ...
Park Sean S - - 2011
OBJECTIVE:: To prospectively assess the quality of life (QOL) and hearing acuity in vestibular schwannoma (VS) patients after gamma knife surgery (GKS). PATIENTS:: Fifty-nine VS patients. INTERVENTION:: GKS. MAIN OUTCOME MEASURES:: Prospective follow-up algorithm included 36-item Short Form Health Survey (SF-36), Hearing Handicap Inventory (HHI), Dizziness Handicap Inventory (DHI), Tinnitus ...
Alimoglu Yalcin - - 2011
Idiopathic sudden sensorineural hearing loss is a rare disorder of unknown pathogenesis in which hearing is lost partially or totally. About 60 treatment modalities have been described. We aimed to compare the efficacy of hyperbaric oxygen, oral steroid, intratympanic steroid therapy and their combinations in idiopathic sudden sensorineural hearing loss ...
Abdel-Karim Abdul-Rahman R - - 2011
To evaluate the intercatheter reproducibility of catheter-based intracoronary near-infrared spectroscopy (NIRS) for the detection of coronary lipid core plaques (LCPs). The intercatheter in vivo reproducibility of coronary NIRS findings has not been evaluated. NIRS assessment using an automated pullback catheter was performed in triplicates in 10 patients using two different ...
Ben-Yehuda Ori - - 2011
Coronary heart disease (CHD) risk increases with age; yet lipid-lowering therapies are significantly under-utilized in patients > 65 years. The objective was to evaluate the safety and efficacy of lipid-lowering therapies in older patients treated with atorvastatin 10 mg + ezetimibe 10 mg (EZ/Atorva) vs. increasing the atorvastatin dose to ...
Kim Dong Wook - - 2011
Abstract Conclusion: Mean incudostapedial joint (ISJ) angulation of atretic ears was statistically wider than ISJ angulation of non-atretic ears. Postoperative hearing results in the narrow tympanoplasty type II (T2) subgroup were better than those in the wide T2 subgroup. In cases of abnormally wide ISJ angulation, we recommend that partial ...
Arthurs Benjamin J - - 2011
Vestibular schwannomas are benign intracranial tumors arising from the vestibular nerve. Treatment options include observation, stereotactic radiosurgery, fractionated radiotherapy, and microsurgery. We review the evidence describing efficacy and side-effect profiles of each of these modalities. This was accomplished by outlining the results of published meta-analyses and performing a systematic search ...
Senn Pascal - - 2011
Clinical and radiologic outcome analysis after petrous bone cholesteatoma (PBC) removal with simultaneous functional reconstruction. Retrospective case review over an observation period of 16 years (1992-2007). Tertiary referral center. A total of 21 patients (17 adults and 4 children) with PBCs were included, accounting for 3.4% of all cholesteatoma cases ...
Mansour Salah - - 2011
OBJECTIVE:: To develop a radiologic classification of severity of round window involvement in otosclerosis and describe the impact of each class on hearing and outcome of stapes surgery. STUDY DESIGN:: Retrospective chart review with radiologic review of computed tomographic scans. SETTING:: Hospital and private otolaryngology clinics. PATIENTS:: We reviewed computed ...
Lee Jong Bin - - 2011
The effect of intratympanic steroid injection is controversial as salvage or initial treatment option for sudden sensorineural hearing loss (SSNHL) and almost unknown if it is consecutively to use after initial systemic steroids. This study aimed to analyze the efficiency of intratympanic dexamethasone injection (ITDI) as a sequential treatment in ...
Hsu Griffith S - - 2011
Objective. To determine the efficacy of using intraoperative auditory brainstem response (ABR) in improving immediate hearing results of patients undergoing primary laser stapedotomy. Study Design. Case series with chart review. Setting. Community hospital. Subjects and Methods. The study included 32 consecutive patients, with 34 ears undergoing primary stapedotomy by a ...
Messina Martina - - 2011
Purpose: This article describes the approach to atypical placement of central venous catheters (CVC) in dialysis patients with complete untreatable obstruction of central venous vessels. Methods: Five patients with complete obstruction of central venous vessels underwent CT venography and digital venous angiography. After ultrasound-guided and radioscopic-assisted cannulation of the internal ...
Nevoux Jérôme - - 2011
To assess the efficacy of partial ossicular chain reconstruction using autologous cartilage. Prospective study (April 1, 1997, through January 1, 2008). Tertiary academic children's hospital. Two hundred forty-eight children (268 ears) underwent partial ossicular chain reconstruction using a shaped block of tragal cartilage interposed between the head of the stapes ...
Fishbane Steven - - 2011
Hemodialysis (HD) catheters are prone to thrombotic occlusion. We evaluated tenecteplase, a thrombolytic, for the treatment of dysfunctional HD catheters. Patients with tunneled HD catheters and blood flow rate (BFR) <300 mL/min received open-label tenecteplase (2 mg/lumen) for a 1 h intracatheter dwell. Treatment success was defined as BFR ≥ ...
Lee Hans J - - 2011
Background and objective:  This study evaluates two different techniques for topically anaesthetizing the airway with lidocaine during curvilinear probe endobronchial ultrasound bronchoscopy (CP-EBUS): standard injection through the working channel and spray catheter application. Methods:  This was a randomized, non-blinded, single-centre pilot study. Patients with plans for CP-EBUS under moderate sedation ...
Sauter Daniel D Institute of Molecular Virology, Ulm University Medical Center, 89069, Ulm, - - 2011
A new subgroup of HIV-1, designated Group P, was recently detected in two unrelated patients of Cameroonian origin. HIV-1 Group P phylogenetically clusters with SIVgor suggesting that it is the result of a cross-species transmission from gorillas. Until today, HIV-1 Group P has only been detected in two patients, and ...
Kim Jin Wook - - 2011
We prospectively investigated the efficacy of corticosteroid medication in salvaging acute hearing deterioration after radiosurgery for vestibular schwannoma (VS) and analyzed prognostic factors for hearing preservation. Forty-one patients with serviceable hearing treated with gamma knife radiosurgery between 2004 and 2006 were included. Nineteen patients who suffered acute hearing deterioration after ...
Tyagi Asha - - 2010
To determine if epidural volume extension and continued postoperative epidural injections prevent hearing loss associated with a 23-gauge (G) Quincke spinal needle. Prospective, double blinded trial. Operating rooms. 30 adult patients scheduled for lower abdominal or perineal surgery during spinal anesthesia. Patients were divided into two groups of 15 each. ...
Chen Yang - - 2010
to evaluate the effectiveness of transtympanic methylprednisolone injection in patients with refractory sudden sensorineural hearing loss via endoscopic diode laser myringotomy. thirty-six sudden sensorineural hearing loss patients who failed routine oral steroid therapy and two patients with a contraindication to systemic steroid received intratympanic methylprednisolone injections at the round window ...
Régis Jean - - 2010
The roles of the wait-and-see strategy and proactive Gamma Knife surgery (GKS) in the treatment paradigm for small intracanalicular vestibular schwannomas (VSs) is still a matter of debate, especially when patients present with functional hearing. The authors compare these 2 methods. Forty-seven patients (22 men and 25 women) harboring an ...
Gerosa Massimo - - 2010
During the past decades, in small-to-medium size vestibular schwannomas, Gamma Knife surgery (GKS) has become a reliable therapeutic option because of either excellent local tumor control or minimal morbidity, with cranial neuropathy becoming increasingly rare. Although still insufficiently analyzed in larger cohorts of patients with long-term follow-ups, adequate chances of ...
Tringali Stéphane - - 2010
To assess the contribution of preoperative radiologic appearance of vestibular schwannoma (VS) on the magnetic resonance imaging in constructive interference in steady-state sequences and demonstrate if the degree of the internal auditory canal (IAC) filling is correlated with hearing and facial preservation. A group of 278 patients who underwent VS ...
Ahn J H - - 2010
Clin. Otolaryngol. 2010, 35, 486-489 Objective:  To evaluate the therapeutic efficacy of coenzyme Q10 added to systemic steroid in patients with idiopathic sudden sensorineural hearing loss. Design:  A controlled prospective study. Setting:  Asan medical center, University of Ulsan College of Medicine. Participants:  Between August 2007 and October 2008, the first ...
Kim Min-Beom - - 2010
The aim of this study was to compare the hearing outcomes between canal wall up mastoidectmy (CWUM) and canal wall down mastoidectmy (CWDM). One hundred seventy one chronic suppurative otitis media (CSOM) patients were enrolled in this retrospective study. The patients who underwent the second staged ossiculoplasty at least 6 ...
Ligi Isabelle - - 2010
To assess the impact of continuous incident reporting and subsequent prevention strategies on the incidence of severe iatrogenic events and targeted priorities in admitted neonates. We performed preintervention (January 1 to September 1, 2005) and postintervention (January 1, 2008, to January 1, 2009) prospective investigations based on continuous incident reporting. ...
Pierce Dwayne A - - 2010
The use of tunneled hemodialysis catheters, or permcaths, either for temporary dialysis access before arteriovenous fistula or arteriovenous graft maturation or for long-term dialysis access, is associated with increased risk of catheter clotting and infection. Catheter locking solutions are routinely used to maintain patency in these catheters between dialysis sessions. ...
Parikh Neeti B - - 2010
To evaluate the retention rate of silicone punctal plugs placed in patients with dry eye in a general clinic setting by ophthalmology residents. A cohort study reviewing charts of 88 patients who underwent punctal plug placement in the resident clinic at The New York Eye and Ear Infirmary from January ...
Chen Chia-Hung - - 2012
The study aimed to assess the clinical efficacy of pigtail catheter drainage for patients with a first episode of secondary spontaneous pneumothorax (SSP) and different associated conditions. We retrospectively reviewed the records of patients with SSP who received pigtail catheter drainage as their initial management between July 2002 and October ...
Oto Jun - - 2011
Catheter hub contamination has been recognized as a source of catheter-related bloodstream infections. We have investigated the efficacy of a protection cap for a needleless injection device in preventing intraluminal catheter contamination, compared with a conventional 3-way stopcock. Adult patients requiring an intravascular catheter placement for at least 48 hours ...
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