Search Results
Results 401 - 450 of 2157
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Persson L M - - 2009
Post-thrombotic syndrome (PTS) is a well-recognized condition that develops after symptomatic deep venous thrombosis, but the clinical significance and late complications of asymptomatic deep venous thrombosis (ADVT) are unclear. OBJECTIVE: To determine whether ADVT following minor surgery affects venous function and contributes to the later development of PTS. PATIENTS/METHODS: The ...
Pastore Fabio - - 2009
We present a case of a mechanical mitral valve thrombosis in a 37-year-old woman occurred 2 days after a Caesarean delivery. The patient stopped warfarin and initiated low-molecular-weight heparin 1 week before the programmed delivery. Subsequently the diagnosis of thrombosis, heparin infusion was started however unsuccessfully and eventually patient was ...
Patanè Salvatore - - 2009
From time to time, it may be necessary to interrupt oral anticoagulant therapy in preparation for surgical procedures. In high-risk patients or for longer periods, unfractionated or low-molecular-weight heparin bridging treatment has been reported safe. This case focuses attention on treatment failure of low molecular weight heparin bridging therapy in ...
Turpie Alexander G G - - 2009
BACKGROUND: Prophylaxis for venous thromboembolism is recommended for at least 10 days after total knee arthroplasty; oral regimens could enable shorter hospital stays. We aimed to test the efficacy and safety of oral rivaroxaban for the prevention of venous thromboembolism after total knee arthroplasty. METHODS: In a randomised, double-blind, phase ...
Taneja Ravi - - 2009
PURPOSE: Exposure to cardiopulmonary bypass (CPB) is associated with postoperative coagulopathy and hemorrhage. Recent literature indicates that heparin rebound occurs almost universally following cardiac surgery. We conducted this pilot study to evaluate if the presence of residual circulating heparin following cardiac surgery can be diagnosed by elevation of activated partial ...
Eriksson B I - - 2009
A once-daily dose of rivaroxaban 10 mg, an oral, direct Factor Xa inhibitor, was compared with enoxaparin 40 mg subcutaneously once daily for prevention of venous thromboembolism in three studies of patients undergoing elective hip and knee replacement (RECORD programme). A pooled analysis of data from these studies (n = ...
Kadota Hideki - - 2009
BACKGROUND: Because of the low incidence of late thrombosis in free flaps used for head and neck reconstruction, the risk factors, prognosis, and the optimal method of treatment are unclear. METHODS: The timing of thrombosis, types of flaps, occluded vessels, causative factors, previous irradiation, and salvage rates were reviewed and ...
Puggioni Alessandra - - 2009
The safety of radiofrequency ablation (RFA) of the great saphenous vein (GSV) in patients with previous history of deep venous thrombosis (DVT) has not been determined. From April 2003 to June 2006, 274 patients (68% women; mean age, 60 years +/- 15 years) underwent 293 consecutive RFA procedures. In the ...
Chua Karen S G - - 2009
OBJECTIVES: To determine the prevalence and risk factors of asymptomatic lower-limb deep venous thrombosis (DVT) among Asians in inpatient rehabilitation after traumatic brain injury (TBI). DESIGN: a prospective observational study. PARTICIPANTS: Fifty-six (35 males and 21 females) Asian individuals with TBI with a median of 25 days to rehabilitation. The ...
Stashenko Gregg J - - 2009
BACKGROUND: Venous thromboembolism (VTE) is a life-threatening condition for which thrombolytic therapy may be beneficial. The appropriate setting for the use of thrombolytic therapy remains controversial. More than 10 years ago we described the case-based practice patterns for the use of thrombolytics in VTE, and now, in the context of ...
Hanke Christof Andreas - - 2009
Heparin-induced thrombocytopenia (HIT II) in childhood is rare. Suspected HIT II requires immediate diagnostic and therapeutic measures in order to avoid potentially life threatening complications. Heparin must be stopped immediately. We report on a 6-year old boy who required cardiac surgery due to tetralogy of Fallot. To our knowledge he ...
Enden T - - 2009
BACKGROUND: Approximately one in four patients with acute proximal deep vein thrombosis (DVT) given anticoagulation and compression therapy develop post-thrombotic syndrome (PTS). Accelerated removal of thrombus by thrombolytic agents may increase patency and prevent PTS. OBJECTIVES: To assess short-term efficacy of additional catheter-directed thrombolysis (CDT) compared with standard treatment alone. ...
Germing Alfried - - 2010
In this prospective study, we aimed to document the rate and localization of deep venous thromboses in patients with spinal cord injuries. Patients with paraplegia or tetraplegia were screened by a serial color duplex sonography protocol for deep venous thrombosis within the first 36 hours after admission, at day 7, ...
Kerlin Bryce A - - 2009
To identify clinical variables predictive of the risk of thromboembolism (TE), and to confirm the incidence of TE in primary and secondary childhood nephrotic syndrome (NS). A comprehensive chart review identified 326 children with NS from any cause evaluated between 1999 and 2006. These patients had a total of 1472.8 ...
Mavrikakis Ioannis - - 2009
PURPOSE: To describe venous thrombosis as a mechanism of clinical change in venous and combined venous lymphatic malformations of the orbit and to attempt histopathologically to distinguish the various vascular components of these lesions using immunohistochemistry with CD31 and D2-40 antibodies. DESIGN: Retrospective, comparative, interventional case series. PARTICIPANTS: Twelve patients ...
Akram A R - - 2009
BACKGROUND: Relatively little is known about prognosis in patients for whom suspected pulmonary embolism (PE) is refuted by imaging. AIM: This prospective study of suspected PE therefore compared clinico-radiological features and outcome in patients with and without PE. DESIGN AND METHODS: Computed tomographic pulmonary angiography (CTPA) confirmed or refuted PE ...
Levy Mitchell - - 2009
PURPOSE: The safety of using heparin concomitantly with drotrecogin alfa (activated) {DrotAA} was explored in the XPRESS study. No heparin effect on mortality was observed. Safety results from that study are explored in more detail. METHODS: A randomized, double-blind trial of prophylactic heparin versus placebo in severe sepsis patients treated ...
Patel Apurva - - 2009
OBJECTIVE: The rate of venous thromboembolism in patients undergoing multimodality therapy for lung malignancy and the impact of preoperative venous thromboembolism on postoperative outcome have not been analyzed systematically. METHODS: We performed a retrospective review of all patients undergoing induction therapy before lung resection for non-small cell lung cancer and ...
Tardy-Poncet B - - 2009
PURPOSE: Danaparoid is a safe and effective drug for the treatment of heparin-induced thrombocytopenia (HIT). We describe an uncommon complication: danaparoid cross-reactivity with HIT antibodies. DESIGN AND SETTING: A retrospective observational multicenter study on HIT was conducted in France. In this study concerning HIT patients treated with lepirudin, 12 patients ...
Naeem M A - - 2009
Deep venous thrombosis (DVT) and pulmonary embolism (PE) are common complications in trauma patients. Fibrin-related markers (FRMs), such as fibrin and fibrinogen degradation products (FDPs), D-dimer, and soluble fibrin (SF), are considered to be useful for the diagnosis of thrombosis (DVT). We report on 3-month follow-up of fibrinolytic activity after ...
Nakase J - - 2009
PURPOSE: To compare the prevalence of deep vein thrombosis (DVT), pulmonary thromboembolism (PTE), and bleeding complications in patients receiving heparin or danaproid after hemiarthroplasty or osteosynthesis for hip fractures. METHODS: 37 men and 138 women aged 47 to 100 (mean, 80) years underwent either hemiarthroplasty or osteosynthesis for hip fractures; ...
Gupta Nilesh - - 2009
The studies on excision wound healing model reveals significant wound healing activity of the methanolic leaf extract (simple ointment 5%) of "Artocarpus heterophyllus" ham which is comparable with standard (Betadine). In the excision model, the period of epithelization, of the extract treated group was found to be higher than the ...
Chin P L - - 2009
PURPOSE: To compare the efficacy and safety of different modes of thromboembolic prophylaxis for elective total knee arthroplasty (TKA) in Asian patients. METHODS: 440 low-risk patients undergoing TKA were randomised into 4 equal groups: (1) no prophylaxis (control), (2) graduated compression stockings (GCS), (3) intermittent pneumatic compression (IPC), and (4) ...
Yakut Zeynep Ilerisoy - - 2009
OBJECTIVE: To evaluate the role of the venous system in cyclical mastalgia. MATERIALS AND METHODS: 25 healthy women and 39 women with cyclic mastalgia underwent venous Doppler examination in both pre- and postmenstrual period. Upper-outer quadrant veins of breast were evaluated. The impedance indices of both groups were compared in ...
Stender Mogens T - - 2009
PURPOSE: The study examined if preoperative plasma D-dimer level was associated with the postoperative cumulative incidence of deep venous thrombosis in patients with colorectal cancer admitted for intended curative surgery. METHODS: In 176 consecutive patients with newly-diagnosed colorectal cancer and absence of preoperative deep venous thrombosis, we measured the preoperative ...
Gorman Peter H - - 2009
BACKGROUND: To determine whether the prophylactic placement of an inferior vena cava (IVC) filter after acute spinal cord injury (SCI) causes an increased incidence of deep venous thrombosis (DVT). METHODS: A retrospective chart review was conducted employing charts from patients admitted to the SCI service of one inpatient rehabilitation center ...
Viliani T - - 2009
AIM: Mechanical edema (MO) is frequently found in a lot of the lower extremities' orthopedic diseases. In absence of deep vein thrombosis, MO is caused by the change in the dynamics of calf muscle pump with venous hypertension and by the change in capillary permeability which offsets the extra-vascular fluid ...
Boeer Klas - - 2009
Deep venous thrombosis is a common disease that may lead to life-threatening embolism of the lung as a common complication. Therefore, early diagnosis followed by sufficient treatment is necessary to decrease mortality of this disease. D-dimer testing is established as a standard to rule out deep venous thrombosis in selected ...
Goel D P - - 2009
The incidence of deep-vein thrombosis and the need for thromboprophylaxis following isolated trauma below the knee is uncertain. We have investigated this with a prospective randomised double-blind controlled trial using low molecular weight heparin with saline injection as placebo in patients aged between 18 and 75 years who had sustained ...
Sen Serdar - - 2009
BACKGROUND: The protective effects of topical mitomycin-C (MMC) have been well documented for tracheal stenosis; however, to the best of our knowledge, the use of heparin as an anti-inflammatory agent to support wound healing in upper airway surgery was not studied before. The aim of this study was to investigate ...
Ashrani Aneel A - - 2009
Post-thrombotic syndrome (PTS) is a long-term complication of deep-vein thrombosis (DVT), manifesting as swelling, pain, edema, venous ectasia, and skin induration of the affected limb. PTS has been estimated to affect 23-60% of individuals with DVT, frequently occurring within 2 years of the DVT episode. Symptomatic DVT, post-operative asymptomatic DVT, ...
Prandoni Paolo - - 2009
Despite considerable progress in the diagnosis and treatment of deep-vein thrombosis (DVT) of the lower extremities, one of every 2-3 patients will develop within 2 years post-thrombotic sequelae, which are severe in approximately 10% of cases and produce considerable socio-economic consequences. Among factors potentially related to the development of the ...
Ghaye B - - 2009
The aim of our study is to investigate prospectively the quantitative relationship between deep venous thrombosis (DVT) and acute pulmonary embolism (PE). 110 patients clinically suspected of having venous thromboembolic disease underwent combined CT pulmonary angiography (CTPA) and venography of lower limb veins. 44 patients presented with clinical signs of ...
Kimura Kazumasa - - 2009
The authors evaluated the prophylactic protocols with unfractionated heparin (UFH) and warfarin in Japanese patients who underwent total knee arthroplasty (TKA) for osteoarthritis knee in regard to bleeding complications. Fifty-six patients who underwent TKA for osteoarthritis knee with the use of methylmethacrylate were included. Subcutaneous UFH and warfarin were administered ...
Zibaeenezhad Mohammad Javad - - 2009
OBJECTIVE: The aim of this randomized trial was to evaluate whether omission of heparin infusion after successful coronary interventions increased the incidence of ischaemic complications. Continuous heparin infusion after percutaneous coronary interventions could increase the occurrence of bleeding; however, the probable advantages of prolonged heparin infusion are unknown. METHODS AND ...
Roumen-Klappe E M - - 2009
BACKGROUND: The aim of this study was to investigate whether inflammatory markers (interleukin-6 [IL-6] and C-reactive protein [CRP]) in the acute phase of deep vein thrombosis (DVT) are associated with elevated venous outflow resistance (VOR), thrombosis score (TS), reflux and the development of clinical post-thrombotic syndrome (PTS). METHODS: In 110 ...
Zeymer Uwe - - 2009
AIMS: We sought to determine the efficacy of enoxaparin in unselected patients with STEMI treated with primary percutaneous coronary intervention in clinical practice. METHODS AND RESULTS: In a retrospective analysis of the prospective MITRA-plus registry we compared the outcomes of patients with primary PCI and either enoxaparin or unfractionated heparin. ...
Alsayegh Faisal - - 2009
The aim of this study is to assess the practice of heparin administration in real-life situations. This study was conducted at the coronary care unit (CCU) in one of the busiest hospitals in Kuwait; with special attention to the rate of heparin resistance, potential factor that may predict resistance or ...
Torigoshi Takafumi - - 2009
BACKGROUND: Antibodies to the heparin-platelet factor-4 (HPF-4) complex (HIT antibodies) have been observed in patients with heparin-induced thrombocytopenia (HIT). These antibodies are thought to be involved in thrombosis through activation of platelet/endothelial cells. This prospective study was conducted to determine the incidence of post-operative HIT antibodies to assess the associated ...
Arcelus Juan I - - 2009
Postoperative venous thromboembolism (VTE) represents a serious and potentially fatal complication that affects 40% to 60% of patients undergoing major orthopedic surgery and not receiving antithrombotic prophylaxis. Several prophylactic modalities, including pharmacological agents such as oral vitamin K antagonists (VKA) and low molecular weight heparins (LMWH), have been shown to ...
Datta Indraneel - - 2009
Non-operative management of blunt hepatic trauma is successful in the majority of hemodynamically stable patients. Due to the risk of recurrent hemorrhage, pharmacologic deep venous thrombosis (DVT) prophylaxis is often delayed. The optimal timing of prophylaxis is unclear. A multi-centre, retrospective review of patients with blunt hepatic injuries presenting between ...
Kiernan Thomas J - - 2009
Deep venous thrombosis (DVT) is a highly prevalent clinical problem associated with significant mortality and morbidity. In the United States alone, it is estimated that DVT affects approximately 50 per 100,000 people per year. This results in >600,000 inpatient and outpatient treatments per year and accounts for approximately 100,000 deaths ...
Ferro José M - - 2009
BACKGROUND: Around 15% of patients die or become dependent after cerebral vein and dural sinus thrombosis (CVT). METHOD: We used the International Study on Cerebral Vein and Dural Sinus Thrombosis (ISCVT) sample (624 patients, with a median follow-up time of 478 days) to develop a Cox proportional hazards regression model ...
Dobrev Dobromir - - 2009
Patients with atrial fibrillation taking vitamin-K antagonists and undergoing invasive interventions or large surgery procedures are at highest risk of bleeding complications. Therefore, the temporary interruption of vitamin-K antagonists and bridging with heparin is a frequent clinical need, particularly in patients with high risk for stroke. The management of such ...
Cindolo Luca - - 2009
OBJECTIVES: The risk of developing venous thromboembolism (VTE) in urologic patients undergoing major surgery without thromboprophylaxis is high (up to 40%). The aims were to study the acceptability rate of and overall patient satisfaction with an automatic sequential leg compression system and the short-term effectiveness of a combined VTE prevention ...
Sabry Alaa - - 2009
Low-molecular-weight heparins have been suggested as providing well tolerated, efficient, convenient and possibly more cost-effective anticoagulation for haemodialysis than unfractionated heparins (UFHs). A single-bolus dose at the start of haemodialysis effectively prevents clot formation in the dialyser and air trap with fewer side effects and possible benefits on uraemic dyslipidaemia. ...
Duggan Sean T - - 2009
Rivaroxaban (Xarelto), an oral oxazolidinone-based anticoagulant, is a potent, selective direct inhibitor of factor Xa that is used in the prevention of venous thromboembolism (VTE) in adult patients after total hip replacement (THR) or total knee replacement (TKR) surgery. In four large, clinical trials, oral rivaroxaban was more effective than ...
Oudemans-van Straaten Heleen M - - 2009
INTRODUCTION: Renal insufficiency increases the half-life of low molecular weight heparins (LMWHs). Whether continuous venovenous hemofiltration (CVVH) removes LMWHs is unsettled. We studied hemostasis during nadroparin anticoagulation for CVVH, and explored the implication of the endogenous thrombin potential (ETP). METHODS: This cross-over study, performed in a 20-bed teaching hospital ICU, ...
Haas Steven B - - 2009
A variety of pharmacologic and mechanical means can be used to prevent thromboembolic disease following total hip or knee arthroplasty. The existing pharmacologic options are parenteral heparin, fondaparinux, oral warfarin, and oral acetylsalicylic acid. An oral form of heparin as well as direct thrombin inhibitors of factors IIa, IXa, and ...
Snead Dale - - 2009
To advise athletic trainers on the potential for effort thrombosis to occur in nonthrowing athletes and to underscore the importance of early recognition and treatment. An 18-year-old offensive lineman presented with a 1-day history of diffuse shoulder pain with no specific history of injury; swelling and erythema involved the entire ...
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