Search Results
Results 251 - 300 of 1892
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Wu Christopher L - - 2008
It is unclear whether perioperative epidural analgesia is associated with a decrease in mortality in patients who undergo orthopedic procedures. We examined 35,878 patients' data obtained from a random sample of Medicare beneficiaries who underwent elective total knee replacement. Division of patients into 2 groups was based on presence or ...
Hong Daewha - - 2008
BACKGROUND: Despite "clinical lore" among health care providers that treatment with hydromorphone results in improved pain control and fewer adverse side effects, morphine continues to be the first-line medication for postoperative patient-controlled analgesia (PCA). In this study, we compared the efficacy and side-effect profiles of morphine and hydromorphone at concentrations ...
Cata Juan P - - 2008
Spine surgery remains one of the most common procedures for patients with a wide variety of spine disorders. Postoperative pain after major spine surgery is moderate to severe. We retrospectively reviewed 245 medical records of adult patients undergoing major spine surgery who received either patient-controlled epidural analgesia based on local ...
Veering Bernadette T - - 2008
PURPOSE OF REVIEW: Patients undergoing major vascular surgery are at increased risk for postoperative complications due to the high incidence of comorbidities in this population.Epidural anaesthesia provides potential benefits but its effect on morbidity and mortality is unclear. RECENT FINDINGS: Existing studies fail to demonstrate improved clinical outcome and reduced ...
Ducharme James - - 2008
OBJECTIVES: The aim of the study was to examine the association between triage scoring systems and triage priority scores on time to initial emergency department (ED) analgesic administration. METHODS: An observational, multicenter, prospective, cohort study was conducted at 20 US and Canadian EDs. Centers from the United States used the ...
Heller Lior L Department of Plastic Surgery and Anesthesiology, Division of Quantitative Sciences, University of Texas MD Anderson Cancer Center, Houston, Texas 77030, - - 2008
: This study assessed the efficacy of a continuous infusion pump system for postoperative pain control at muscle-sparing transverse rectus abdominis musculocutaneous (TRAM) flap donor sites. : In this prospective, randomized, double-blind trial, a dual-catheter continuous infusion pump system was placed in the muscle-sparing TRAM flap donor-site area in all ...
Farouk S - - 2008
BACKGROUND: This prospective, randomized, double-blind study was designed to evaluate the preemptive and preventive analgesic efficacy of adding magnesium to a multimodal regimen of patient-controlled epidural analgesia (PCEA) in patients undergoing abdominal hysterectomy. METHODS: Ninety patients were randomly assigned to one of the three groups. Pre-magnesium patients received bolus of ...
Turunen Pertti - - 2009
BACKGROUND: The primary hypothesis for this study was that epidural analgesia reduces the use of opioids and thus advances bowel function and oral intake and shortens hospital stay after laparoscopic sigmoidectomy performed according to principles of enhanced recovery after surgery. METHODS: For this study, 60 patients with complicated diverticular disease ...
Baltali Sevim - - 2009
OBJECTIVE: To compare the effect of remifentanil and morphine after coronary artery surgery in a patient-controlled analgesia (PCA) protocol. DESIGN: A prospective, randomized, double-blind clinical study. SETTING: Single institution, university hospital. PARTICIPANT: Sixty cardiac surgical patients undergoing primary coronary artery bypass graft (CABG) surgery. INTERVENTIONS: After the operation, patients were ...
Tripi Paul A - - 2008
STUDY DESIGN: A retrospective study of postoperative pain management with intrathecal morphine. OBJECTIVE: Identify the dosing regimen of intrathecal morphine that safely and effectively provides postoperative analgesia with minimal complications in patients with idiopathic scoliosis undergoing posterior spinal fusion (PSF) and segmental spinal instrumentation (SSI). SUMMARY OF BACKGROUND DATA: Postoperative ...
Kuzma Jerzy - - 2008
BACKGROUND & AIMS: Fast track protocols have been successfully used in abdominal surgery but there are no randomized trials on fast track after appendectomy. The aim of this study was to evaluate the safety and feasibility of fast track perioperative care protocol including early feeding with opioid-sparing analgesia after open ...
Kraft Michael D - - 2008
Postoperative ileus (POI), a transient impairment of bowel function, is considered an inevitable response after open abdominal surgery. It leads to significant patient morbidity and increased hospital costs and length of stay. The pathophysiology is multifactorial, involving neurogenic, hormonal, inflammatory and pharmacologic mediators. Several treatments have been shown to reduce ...
Turan Alparslan - - 2008
BACKGROUND: A single 3 mg intranasal dose of nicotine has been reported to have analgesic properties. We designed placebo-controlled study to test the hypothesis that transdermal nicotine (TDN) administered over a 3-day period would decrease postoperative pain and opioid analgesic usage and improve the recovery process after lower abdominal surgery. ...
Leykin Y - - 2008
BACKGROUND: The aim of this prospective, randomized, double-blind study was to compare the efficacy of parecoxibfor postoperative analgesia after endoscopic turbinate and sinus surgery, with the non-selective non-steroid anti-inflammatory drug (NSAID), ketorolac. METHODS: A total of 50 patients with an ASA physical status I-II, receiving functional endoscopic sinus surgery (FESS) ...
O'Donoghue Joseph M - - 2008
The use of intrapleural (IP) analgesia for controlling post-operative pain in breast reconstruction is not well documented. The objective of this study was to assess the value of IP bupivacaine in those patients undergoing latissimus dorsi breast reconstruction. Twenty-six patients received a single bupivacaine IP injection at induction of anesthesia. ...
Habib Ashraf S - - 2008
BACKGROUND: Previous animal and human studies suggested that nicotine might have an antinociceptive effect. We hypothesized that the preoperative application of a 7 mg nicotine patch would result in reduced postoperative analgesic requirements in patients undergoing radical retropubic prostatectomy (RRP) under general anesthesia. METHODS: Nonsmokers undergoing RRP under general anesthesia ...
Ebneshahidi Amin - - 2008
BACKGROUND: After cesarean section surgery, routine pharmacologic methods of analgesia--opioids and benzodiazepines--may impair the immediate close contact of mother and neonate for their sedative and emetic effects. OBJECTIVES: The aim of this study was to explore the effect of patient-selected music on postoperative pain, anxiety, opioid requirement, and hemodynamic profile. ...
Wang Shen-Chih - - 2008
We present a case of spontaneous intracranial hypotension (SIH) diagnosed from the clinical symptoms and magnetic resonance imaging brain scans. After failure of conservative treatment, and lack of identification of the cerebrospinal fluid leak site, the headache was managed successfully and simply with two applications of an epidural blood patch ...
Richardson Lydia - - 2009
A best evidence topic in cardiac surgery was written according to a structured protocol. The question addressed is whether intrathecal morphine is of benefit to patients undergoing cardiac surgery? Using the reported search 850 papers were identified. Ten papers represented the best evidence on the subject. The author, journal, date ...
Wijeysundera Duminda N - - 2008
BACKGROUND: Although epidural anaesthesia and analgesia have numerous benefits, their effects on postoperative survival are unclear. We therefore undertook a population-based cohort study to determine whether perioperative epidural anaesthesia or analgesia is associated with improved 30-day survival. METHODS: We used population-based linked administrative databases to do a retrospective cohort study ...
- - 2008
(1) A transdermal system for fentanyl, an opiate analgesic, will soon be marketed in France for patient-controlled relief of acute postoperative pain. Pushing a button delivers a dose of fentanyl (contained in a reservoir) into the general circulation by transdermal route, by means of iontophoresis, a needle-free technique; (2) The ...
Biki Barbara - - 2008
BACKGROUND: Regional anesthesia and analgesia attenuate or prevent perioperative factors that favor minimal residual disease after removal of the primary carcinoma. Therefore, the authors evaluated prostate cancer recurrence in patients who received either general anesthesia with epidural anesthesia/analgesia or general anesthesia with postoperative opioid analgesia. METHODS: In a retrospective review ...
Mercadante Sebastiano - - 2008
BACKGROUND: We sought to determine the effectiveness of continuous intrathecal thoracic analgesia (ITA) in comparison with continuous epidural thoracic analgesia (ETA) for the management of postoperative pain after abdominal cancer surgery in a randomised controlled study. MATERIALS AND METHODS: Catheters were inserted at T8-10 level for both techniques. Sixty patients ...
Beilin Benzion - - 2008
Pain may contribute to cognitive decline, which is a common complication in the early postoperative period. We compared the effects of two common pain management techniques, intravenous patient-controlled analgesia (PCA-IV) and patient-controlled epidural analgesia (PCEA), on cognitive functioning in the immediate postoperative period. Patients hospitalized for elective surgery were randomly ...
Cakan Turkay - - 2008
Paracetamol, a centrally acting inhibitor of cyclooxygenase, has less gastrointestinal and platelet-inhibiting side effects and is clinically better tolerated than nonsteroidal anti-inflammatory drugs. Therefore, it will be ideally suited for postoperative pain relief. In this prospective, double-blind, randomized, placebo-controlled study, we evaluated the analgesic efficacy, opioid-sparing effect and effects on ...
Wang F - - 2008
BACKGROUND: The perception of pain is germane to the environmental stimuli. Nurses on surgical wards are the main contributor in influencing patients' psychophysiological fettle. The aim of the study was to investigate the effect of different words, negative or positive, from nurses on postoperative pain therapy with patient-controlled analgesia (PCA). ...
Freedman Bruce M - - 2008
There has been a recent, growing concern regarding narcotic use in surgical patients. This issue, coupled with an ongoing desire to lessen postoperative discomfort, has prompted the search for alternative analgesic regimens. The purpose of this study was to determine whether the addition of pregabalin, an anticonvulsant indicated for the ...
Leykin Yigal - - 2008
PURPOSE: The aim of the study was to compare the efficacy of parecoxib for postoperative analgesia after endoscopic turbinate and sinus surgery with the prodrug of acetaminophen, proparacetamol. MATERIALS AND METHODS: Fifty American Society of Anesthesiology (ASA) physical status I-II patients, receiving functional endoscopic sinus surgery (FESS) and endoscopic turbinectomy, ...
Al-Metwalli R R - - 2008
BACKGROUND: Alpha-2-adrenergic agonists have peripheral analgesic effects. We have assessed the potential analgesic effect of dexmedetomidine after intra-articular administration in arthroscopic knee surgery. METHODS: Sixty patients undergoing arthroscopic knee surgery were randomly assigned into three groups in a double-blind placebo controlled study. The control group received i.v. and intra-articular saline, ...
Benito-de-la-Víbora Javier - - 2008
OBJECTIVE: The hypothesis was that Visual Analog Scale (VAS) scores would be lower, and mechanical wound thresholds (MWT) higher, in cats receiving tolfenamic acid compared to those receiving placebo in the postoperative period following elective ovariohysterectomy. ANIMALS: Sixty-nine client-owned cats. METHODS: A prospective, randomized, blinded and placebo-controlled study was performed ...
Nesher Nahum - - 2008
BACKGROUND: Thoracotomy is associated with severe pain. Large doses of morphine can depress respiratory drive and compromise hemodynamic stability. Ketamine reduces hyperalgesia, prevents opioid tolerance and resistance and lowers morphine consumption. At sub-anesthetic (< or = 500 microg/kg) doses, ketamine rarely produces undesirable hemodynamic alterations. We hypothesized that by combining ...
Mastronardi Luciano - - 2008
STUDY DESIGN: At the end of lumbar microdiscectomy, we administered an emulsion of low-dose epidural morphine and vaseline sterile-oil as carrier for morphine delivery. OBJECTIVE: To evaluate safety and analgesic efficacy of this compound and the impact on long-term epidural scar production. SUMMARY OF BACKGROUND DATA: Epidural analgesia has been ...
Kocabas S - - 2008
BACKGROUND AND OBJECTIVE: This study aimed to investigate the effect of 0.25% levobupivacaine infiltration of the sternotomy wound and the mediastinal tube sites on postoperative pain, morphine consumption and side-effects in patients undergoing cardiac surgery. METHODS: After obtaining Ethics Committee approval and informed consent,50 patients aged 18-65 yr, undergoing coronary ...
Evans George - - 2008
Introduction: This chart review was a quality improvement project to compare three epidural solutions that have been used at a tertiary care academic hospital. The three solutions compared were0.1% Bup./Dilaudid 20ug/cc,0.125% Bup./Dilaudid 20ug/cc and0.125% Bup./Fentanyl 2ug/cc. METHODS: Local REB approval was obtained for this study. Retrospective Chart Review of Patients ...
Di Renna Tania - - 2008
Introduction: A multimodal analgesia protocol (MMAP) for prostatectomy patients, involving pre operative oral NSAIDs, a spinal anesthetic with 4-6 mls of 0.5% bupivicaine with 200 - 400 ug intrathecal morphine combined with a general anesthetic, has been followed for several years at our institution. Post operatively patients receive NSAIDs for ...
Singh A - - 2008
OBJECTIVE: To clinically evaluate and compare the PlasmaKnife to bipolar electrocautery in paediatric tonsillectomy. DESIGN: Prospective comparative non-randomised study. SETTING: Central London teaching hospital with tertiary referrals. PARTICIPANTS: Forty-three patients aged 3-12 years with recurrent tonsillitis or obstructive adenotonsillar hypertrophy awaiting a tonsillectomy were recruited into the study. MAIN OUTCOME ...
Minville Vincent - - 2008
STUDY OBJECTIVE: To determine whether a new transdermal fentanyl patch (TFP) is a good choice for the postoperative pain management of patients undergoing primary total hip arthroplasty compared with patient-controlled analgesia (PCA). DESIGN: Randomized, prospective study. SETTING: University hospital. PATIENTS: 30 patients undergoing primary total hip arthroplasty. INTERVENTIONS: Patients received ...
Wijeysundera Duminda - - 2008
Introduction: Although epidural anesthesia or analgesia has numerous benefits, including improved postoperative analgesia and attenuation of the surgical stress response, its effects on postoperative survival remain controversial. Published randomized controlled trials are underpowered to detect plausible treatment effects.(1)(,)(2) In addition, they often have limited generalizability.(3) We therefore undertook a population-based ...
Tenenbein Paul K - - 2008
PURPOSE: Pulmonary dysfunction commonly occurs following coronary artery bypass graft (CABG) surgery, increasing morbidity and mortality. We hypothesized that thoracic epidural anesthesia (TEA) would improve pulmonary function and would decrease complications in patients undergoing CABG surgery. METHODS: This prospective, randomized, controlled trial was conducted with Ethics Board approval. Fifty patients, ...
Friedly Janna - - 2008
OBJECTIVES: To evaluate whether the use of epidural steroid injections (ESIs) is associated with decreased subsequent opioid use in patients in the Department of Veteran's Affairs (VA) and to determine whether treatment with multiple injections are associated with decreased opioid use and lumbar surgery after ESIs. DESIGN: VA patients undergoing ...
Chen Wan-Chin - - 2008
BACKGROUND AND PURPOSE: Despite advances in diagnosis and treatment, spinal epidural abscess due to Staphylococcus aureus remains a challenge to clinicians. In this study, we describe the clinical features and outcomes of patients with spinal epidural abscess due to S. aureus. METHODS: Thirty one cases of spinal epidural abscess due ...
Bayar Ulkü - - 2008
Preoperative and postoperative psychological factors, postoperative pain, analgesic consumption, treatment satisfaction were compared in patients treated with intravenous patient-controlled analgesia (IV-PCA) or intramuscular analgesics after laparoscopic ovarian cystectomy. Thirty-one women with laparoscopically operated benign ovarian cysts were recruited in Zonguldak Karaelmas University Faculty of Medicine, Department of Obstetrics and Gynecology. ...
Kasó Gábor - - 2008
OBJECTIVE: This study was intended to assess the results of post-operative CT scans in three groups of patients following percutaneous vertebroplasty (VP) using different navigation and injection methods, in an attempt to explain the radiological characteristics of extravertebral cement leakage with relation to needle placement and focused on the ventral ...
Kirou-Mauro Andrea M - - 2009
The primary objective of this study was to determine the prevalence of underdosage of analgesics for pain associated with bone metastases in outpatients referred to the Rapid Response Radiotherapy Program at the Odette Cancer Centre from 1999 to 2006. A prospective database containing data for all patients with bone metastases ...
Cassinelli Ezequiel H - - 2008
STUDY DESIGN: Prospective randomized double-blind placebo-controlled study. OBJECTIVE: The objective of this study was to assess the efficacy of Ketorolac in reducing postoperative pain and morphine requirements following primary multilevel lumbar decompression surgery. SUMMARY OF BACKGROUND DATA: The use of opioid medications following surgical interventions can be complicated by related ...
Ruan Xiulu - - 2008
BACKGROUND: Intraspinal drug delivery therapy has been increasingly used in patients with intractable, nonmalignant pain who fail to respond to conventional treatment or cannot tolerate systemic opioid therapy due to side effects. By infusing small amount of analgesics directly into the cerebrospinal fluid in close proximity to the receptor sites ...
Marandola M - - 2008
BACKGROUND: A high rate of mortality and morbidity has been associated with pancreaticoduodenectomy; the 5-year survival rate is 15% to 25% compared with 1% to 5% among those who did not have any cancer-directed treatment. Systemic rather than surgical complications cause the majority of perioperative deaths, so the anesthesiologist has ...
Sami Mebazaa Mhamed - - 2008
BACKGROUND: combination of ketamine may improve morphine patient controlled analgesia (PCA) but clinical results are still equivocal. AIM: The authors designed a powerful study to evaluate this hypothesis after major abdominal surgery. METHODS: 138 patients undergoing abdominal surgery participated in the randomized double blind study. Patients were allocated to two ...
Levento─člu Sezai - - 2008
BACKGROUND: This study evaluated in a randomized, prospective manner the possible differences in operative time, postoperative pain and analgesic requirement, early complications, time off-work and patient satisfaction between patients undergoing haemorrhoidectomy using the electrocautery (ECH), UltraShears (ultrasonically activated scalpel; USH) or stapled haemorrhoidopexy (SH). METHODS: Patients with symptomatic third-degree or ...
Al-Hunayan Adel - - 2008
PURPOSE: To evaluate the effectiveness of transperineal urethrosphincteric block (TUSB) in providing analgesia during visual internal urethrotomy for patients with anterior urethral strictures. PATIENTS AND METHODS: A total of 26 consecutive patients scheduled for elective visual internal urethrotomy for symptomatic urethral stricture were considered for this prospective study. Twenty-four patients ...
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