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Simeoforidou Marina - - 2011
To investigate the impact of 2 postoperative analgesic regimens on heart rate variability in patients who underwent thoracotomy. A prospective, randomized trial. A single-institutional study in a university hospital. Fifty patients who underwent thoracotomy under combined general anesthesia and thoracic epidural analgesia divided by a number generator into 2 equal ...
Tang Shuai - - 2010
To assess the influences of continuous femoral nerve block (CFNB) and patient-controlled intravenous analgesia (PCIA) on postoperative pain scores,knee rehabilitation,and stress response after total knee arthroplasty (TKA). Totally 32 adult patients scheduled for elective total knee arthroplasty were equally randomized into CFNB group or PCIA group. Intraoperative hemodynamics and fentanyl ...
Argiriadou Helena - - 2011
The authors explored the use of continuous postoperative subpleural paravertebral ropivacaine alone combined with intraoperative S(+)-ketamine or perioperative parecoxib as a new approach to pain control after major thoracotomy. A randomized study. A single university hospital. Eighty patients underwent elective thoracotomy under general anesthesia. Study patients were assigned to 1 ...
DeNino Walter F - - 2010
Despite the 2008 "American Association of Clinical Endocrinologists, The Obesity Society, and American Society for Metabolic and Bariatric Surgery Medical Guidelines for Clinical Practice for the Perioperative Nutritional, Metabolic, and Nonsurgical Support of the Bariatric Surgery Patient," consensus does not exist for postoperative care in laparoscopic adjustable gastric banding (LAGB) ...
Leo S - - 2010
Automated mandatory boluses (AMB), when used in place of a continuous basal infusion, have been shown to reduce overall local anesthetic consumption without compromising analgesic efficacy in patient-controlled epidural analgesia (PCEA). We hypothesized that our PCEA+AMB regimen could result in a reduction of breakthrough pain requiring epidural supplementation in comparison ...
Yousef A A - - 2010
Combined spinal-epidural anaesthesia is commonly used for elective caesarean section. Intrathecal injection produces rapid onset with minimal doses of local anaesthetic and epidural administration can be used to prolong the block. Our study examined the effects of adding magnesium sulphate to epidural bupivacaine and fentanyl in patients undergoing elective caesarean ...
Yano Takeshi - - 2010
The purpose of this study was to investigate the effect of fentanyl on analgesic properties and respiratory responses during an epidural procedure. Sixty patients premedicated with oral brotizolam 0.25 mg were allocated to receive procedural analgesia with saline or 25 or 50 μg of fentanyl. Five minutes after administration, an epidural procedure ...
Sundarathiti Petchara - - 2010
To evaluate the efficacy of thoracic epidural analgesia (TEA) in scoliosis surgery. Descriptive clinical study. University hospital. 15 ASA physical status I, II, and III patients undergoing thoracolumbar scoliosis correction. TEA was performed at three to 5 cm cephalad to the incision, and 5 to 10 mL of 0.125% - ...
Hugunin Kelly M S - - 2010
Sepsis research relies on animal models. The models that most closely resemble clinical disease, such as cecal ligation and puncture, require surgery. After surgery, analgesics may not be included in experimental protocols because of concern over effects on inflammatory responses. This often generates animal welfare controversies within institutions; however, there ...
Pamnani Anup - - 2010
A recombinant human antithrombin (rhAT; generic name: antithrombin Alfa) has recently been developed. A 37 year-old parturient with hereditary antithrombin deficiency, receiving rhAT infusion therapy, who successfully received an epidural catheter for analgesia and anesthesia during labor and cesarean delivery, is presented.
Soumpasis Ioannis - - 2010
There is evidence from previous studies that deeper anaesthetic levels reduce postoperative pain along with analgesic requirements. The aim of this study was to confirm this observation during major urological procedures under sevoflurane anaesthesia. Seventy ASA I or II patients undergoing radical prostatectomy or nephrectomy were randomly allocated into two ...
Bakshi Sumitra G - - 2010
This report describes a noninterventional audit of current patient-controlled analgesia (PCA) use in an Indian cancer hospital over a 1-year period. Because there appeared to be an underutilization of PCA in the authors' hospital, they performed this audit. A major reason to start PCA was inadequate analgesia despite ongoing epidural ...
Stiglitz D K - - 2010
Preventive analgesia is defined as the persistence of the analgesic effects of a drug beyond the clinical activity of the drug. The N-methyl D-aspartate receptor plays a critical role in the sensitisation of pain pathways induced by injury. Nitrous oxide inhibits excitatory N-methyl D-aspartate sensitive glutamate receptors. The objective of ...
Spreng U J - - 2010
Recently, high-volume local infiltration analgesia (LIA) in total knee arthroplasty (TKA) has been introduced, but dosage, timing, and effects of adjuvants are still debated. We randomized 102 patients undergoing TKA to receive either epidural analgesia (EDA group) or LIA (ropivacaine 150 mg and epinephrine 0.5 mg) combined with ketorolac 30 ...
Vallejo M C - - 2010
Epidural analgesia is widely used for pain relief during labor. The purpose of this study was to determine if ultrasound measurement of the depth from skin to epidural space before the epidural technique decreases the failure rate of labor analgesia. A secondary objective was to correlate ultrasound depth to the ...
Lu Chueng-He - - 2010
BACKGROUND/PURPOSE: Peripheral deafferentation induced by neuraxial anesthesia reduces the degree of cortical arousal. This study investigated whether epidural analgesia blockade decreased sedation, as measured by the rapidly extracted auditory evoked potentials index, A-line autoregressive index (AAI) and Ramsay Sedation Scale (RSS) in sedated surgical intensive care patients, and looked at ...
Hakim Sameh Michel - - 2010
BACKGROUND: The aim of the current study was to investigate the effect of administration of cosyntropin after accidental dural puncture (ADP) on the incidence of postdural puncture headache (PDPH) and the need for therapeutic epidural blood patch (EBP). METHODS: Ninety parturients who suffered an ADP were studied. After delivery, patients ...
Ong Johnny C A - - 2010
To determine whether continuous infiltration of local anaesthetic can reduce the pain score and morphine use over 48 hours after total knee arthroplasty (TKA). 11 men and 43 women aged 50 to 82 years who underwent unilateral TKA for osteoarthritis were recruited. They were randomised into 3 groups. In group ...
Ittichaikulthol Wichai - - 2010
BACKGROUND: Nonsteroidal antiinflammatory drugs (NSAIDs) in combination with opioids is a model of multimodal analgesia. NSAIDs have the oral and parenteral forms. OBJECTIVE: The aim of the present study was to evaluate the efficacy of celecoxib compared with placebo and parecoxib after total hip or knee arthroplasty. MATERIAL AND METHOD: ...
Duman Ates - - 2010
STUDY OBJECTIVE: To compare the efficacy of 50 mug and 25 mug doses of intrathecal morphine on postoperative pain in patients undergoing transurethral resection of the prostate (TURP) with low-dose bupivacaine. DESIGN: Randomized, double-blinded study. SETTING: Konya Hospital. PATIENTS: 70 ASA physical status I, II, and III patients. INTERVENTIONS: Patients ...
Machino Masaaki - - 2010
Systemic opioids are known to be effective for controlling postoperative pain. Intrathecal morphine administration can be performed in a simple manner concurrently with spinal anesthesia. The purpose of this study was to investigate the efficacy of intrathecal morphine administration for the postoperative analgesia of lower extremity fractures. A prospective randomized ...
Inanoglu Kerem - - 2010
In this study, we aimed to compare the effects of ropivacaine alone and ropivacaine plus tramadol administered epidurally for postoperative analgesia in children. Following Ethics Committee approval and informed parent consent, 44 children aged between 2 and 12 years, with ASA physical status I or II, who were undergoing major abdominal ...
Curatolo Michele - - 2010
Although it is clear that regional analgesia in association with general anaesthesia substantially reduces postoperative pain, the benefits in terms of overall perioperative outcome are less evident. The aim of this nonsystematic review was to evaluate the effect on middle and long-term postoperative outcomes of adding regional perioperative analgesia to ...
Liu Spencer S - - 2010
BACKGROUND AND OBJECTIVES: Patient-controlled epidural analgesia(PCEA) has been shown to be superior to intravenous patient-controlled analgesics (PCA) for postoperative analgesia after thoracic, abdominal, pelvic, and lower extremity surgery. However, it is unclear which opioid is optimal for PCEA. Hydromorphone has potential advantages, yet there are no data to establish its ...
Uzun Sennur - - 2010
Combined analgesic regimens produce sufficient analgesia by additive or synergistic effects, and reduce the total dose of analgesics and minimise adverse effects. We investigated the metamizole, paracetamol and morphine combination with respect to postoperative pain treatment in lumbar disc surgery. After Ethics Committee approval and informed consent, 63 patients were ...
Yukawa Yasutsugu - - 2010
A case-control clinical study of preemptive analgesia for postoperative pain was conducted. To compare the efficacy of 2 preemptive analgesics: continuous subcutaneous morphine alone (SC) and continuous subcutaneous morphine combined with single intrathecal injection of morphine (SI). Systemic opioids are known to be effective for controlling the postoperative pain. Only ...
Jia Dong-Lin - - 2010
Early studies showed that naloxone infusion decreases the incidence of morphine-related side effects from intravenous patient-controlled analgesia. This study aimed to determine whether naloxone preserved analgesia while minimizing side effects caused by intravenous tramadol administration. Eighty patients undergoing general anesthesia for cervical vertebrae surgery were randomly divided into four groups. ...
Frassanito L - - 2010
BACKGROUND AND OBJECTIVES: Total knee arthroplasty often results in marked postoperative pain. A recent meta-analysis supports the use of femoral nerve block or alternatively spinal injection of morphine plus local anaesthetic for post-operative analgesia. On the other hand, the use of intrathecal morphine may be associated with a large number ...
Keita Alassane - - 2010
OBJECTIVE: To investigate the effect of preoperative meloxicam administration on postoperative stress and pain induced by surgical castration in piglets. STUDY DESIGN: Prospective, blinded, randomized clinical trial. ANIMALS: One hundred and eighty male piglets of <1 week of age. METHODS: Castration was performed on 150 piglets which had received either ...
Fu P L - - 2010
A total of 100 osteoarthritis patients undergoing unilateral total knee arthroplasty were randomly assigned to receive either a multimodal analgesia protocol, comprising oral celecoxib and tramadol before and after surgery and intra-articular injection of large doses of morphine, ropivacaine, adrenaline and betamethasone during surgery (trial group), or oral and intra-articular ...
Ghatak Tanmoy - - 2010
For treatment of intra and postoperative pain, no drug has yet been identified that specifically inhibits nociception without associated side effects. Magnesium has antinociceptive effects in animal and human models of pain. The current prospective randomised double-blind study was undertaken to establish the effect of addition of magnesium or clonidine, ...
Lee Nan-Ju - - 2010
There is a legal obligation to explain the procedure and use of epidural analgesia in labor primarily due to the possibility of potential risks and associated complications. The present study details on the survey carried out to ascertain the current status of obtaining informed consent (IC) for explaining the epidural ...
Sandhu Trichak - - 2011
This study aimed to investigate the effect of preemptive etoricoxib compared with placebo in laparoscopic cholecystectomy. This randomized, double-blind, placebo-controlled study enrolled 120 patients requiring elective laparoscopic cholecystectomy. The patients were randomized to receive either etoricoxib 120 mg plus diazepam or placebo plus diazepam. Postoperatively, the visual analog score (VAS) ...
Griffiths James D - - 2010
BACKGROUND: The transversus abdominis plane (TAP) block is a recently described technique involving injecting local anesthetic between the internal oblique and transversus abdominis layers of the abdominal wall. It has been shown to be effective in reducing morphine consumption and improving postoperative pain relief in several clinical settings. METHODS: We ...
Weinberg L - - 2010
We performed a prospective randomised trial to evaluate the analgesic efficacy of interpleural analgesia in patients undergoing hepatic resection. The control group (n = 25) received multimodal analgesia with intravenous morphine patient-controlled analgesia; in addition, the interventional group (n = 25) received interpleural analgesia with a 20-ml loading dose of ...
Lin Mei-Chi - - 2010
OBJECTIVE: Epidural patient-controlled analgesia (EPCA) with a mixture of low-concentration levobupivacaine (0.0625% or 0.1%) plus fentanyl, with basal infusion, has been extensively used for postoperative analgesia in our allied institutions. To elucidate whether these two EPCA regimens provide satisfactory analgesia, we compared the analgesia efficacy and incidence of drug-related side ...
Mikuni Ikuomi - - 2010
STUDY OBJECTIVE: To evaluate the analgesia following cesarean delivery and the frequency of side effects of intrathecal morphine when combined with a continuous epidural infusion. DESIGN: Randomized, double-blinded study. SETTING: University hospital. PATIENTS: 76 ASA physical status I and II term parturients undergoing cesarean delivery with combined spinal-epidural anesthesia. INTERVENTIONS: ...
Emir Esad - - 2010
Pain intensity may be high in the postoperative period after spinal vertebral surgery. The aim of the study was to compare the effectiveness and cost of patient controlled analgesia (PCA) with tramadol versus low dose tramadol-paracetamol on postoperative pain. A total of 60 patients were randomly divided into two groups. ...
Filingeri Vincenzino - - 2010
BACKGROUND: This randomized study compared results obtained with the Ferguson's technique for the treatment of hemorrhoids performed with a radiofrequency (RF) scalpel and traditional diathermy. METHODS: 28 patients affected by grade IV hemorrhoids were randomized to receive either the Ferguson operation with the RF scalpel (group A) or traditional diathermy ...
Wuethrich Patrick Y - - 2010
BACKGROUND: There are no data on lower urinary tract function during postoperative thoracic epidural analgesia (TEA). Because selected segmental blockade can be achieved with epidural analgesia, we hypothesized that lower urinary tract function remains unchanged during TEA within segments T4-T11 after open renal surgery. METHODS: In a prospective, open, observational, ...
Essving Per - - 2010
Postoperative pain is often severe after total knee arthroplasty (TKA). We investigated the efficacy of the local infiltration analgesia (LIA) technique, both intraoperatively and postoperatively. 48 patients undergoing TKA were randomized into 2 groups in a double-blind study. In group A, 400 mg ropivacaine, 30 mg ketorolac, and 0.5 mg ...
Al Oweidi Abdelkarim S AS Department of Anesthesiology and Intensive Care Medicine, Jordan University, Queen Rania Street, PO BOX 13046, Amman 11942, Jordan. - - 2010
Recent studies suggest that preemptive analgesia may be effective in reducing postoperative pain. One physiologic explanation may be interference with the endogenous opioid response. We investigated whether long-lasting preoperative preemptive analgesia may have an effect on the hormonal stress response after total hip replacement. 42 patients scheduled for elective hip ...
Rugyte Danguole Ceslava - - 2010
PURPOSE: Optimal postoperative pain management following minimally invasive surgical repair of pectus excavatum is not established. We compared efficacy and adverse effects in patients treated with patient-controlled analgesia (PCA) with those treated with continuous infusion (CI) with morphine in addition to nonsteroidal anti-inflammatory drugs. METHODS: 33 patient records were examined ...
Khafagy Hanan F - - 2010
Dexamethasone has analgesic, anti-inflammatory, and antiemetic effects. This prospective, randomized, double-blind, controlled study was designed to evaluate the efficacy of adding dexamethasone versus fentanyl to epidural bupivacaine on postoperative analgesia. Ninety patients ASA I-II scheduled for lower abdominal surgeries were randomly allocated into three groups to receive a total of ...
Kroon Ulla-Beth - - 2010
To investigate if intrathecally administered morphine combined with a low-dose mode of total intravenous anaesthesia (TIVA) accelerates recovery after abdominal surgery as compared, to patient-controlled analgesia (PCA) combined with anaesthesia, based on volatile anaesthetics. Fifty-three patients who were hysterectomised abdominally were randomised to TIVA or PCA. Their per- and post-operative ...
Xu Yajun - - 2010
BACKGROUND: Thoracic epidural anesthesia can contribute to facilitate the fast-track approach in lung surgery. However, data regarding the effects of thoracic epidural anesthesia on oxygenation during one-lung ventilation (OLV) are scarce and contradictory. Therefore, the authors conducted a prospective, randomized, double-blinded trial in patients undergoing lung surgery under spectral entropy-guided ...
Rao Zahid Akhtar - - 2010
To determine the obstetric outcome in terms of duration of labour and mode of delivery between the walking epidural analgesia with 0.1% Bupivacaine + 0.5% tramadol and routine labour practice. Non-randomized controlled trial. Department of Anaesthesia, Military Hospital, Rawalpindi, from August 2004 to July 2007. Consecutive 50 primiparous patients, ASA-I, ...
Gómez-Cardero Primitivo - - 2010
Postoperative pain control is a challenge in patients undergoing TKA due to side effects and technical limitations of current analgesic approaches. Local anesthetic infiltration through continuous infusion pumps has been shown to reduce postoperative pain in previous studies. We assessed the effectiveness of intraarticular ropivacaine infusions in reducing pain and ...
Choi Daniel X - - 2010
OBJECTIVES: For some procedures, epidural anesthesia and analgesia (EAA) improves clinical outcomes. It is used during pancreatoduodenectomy (PD) to mitigate morbidities and shorten hospitalizations. Although widespread, the use of this practice has not been examined extensively. The objective of this study was to do so. METHODS: A retrospective review of ...
Sandeman D J - - 2010
Postoperative analgesia for male circumcision surgery has been traditionally provided by a landmark-based dorsal penile nerve block (DPNB-LM) or by caudal epidural analgesia (CEA). In this study we report on a retrospective analysis of the effectiveness and safety of CEA, DPNB-LM and ultrasound-guided dorsal penile nerve block (DPNB-US) in our ...
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