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Mohr Michael M Department of Medicine A, Hematology, Oncology and Pneumology, University Hospital Muenster, Muenster, - - 2014
Recurrent respiratory papillomatosis (RRP) is a primary benign disease, which is characterized by papillomatous growth in the respiratory tract. Malignant transformation occurs in only 3-5% of cases, however, local growth of the benign papillomas is interpreted as clinically malignant in a markedly higher proportion of patients. Local surgical or endoscopic ...
Suk Kyung Soo KS Department of Orthopaedic Surgery, Yonsei University College of Medicine, Seoul, - - 2014
Teriparatide markedly increases bone formation and strength, while reducing the incidence of new-onset osteoporotic vertebral compression fractures (OVCFs). In some countries, expenses for teriparatide use are covered by medical insurance for up to 6 months; however, the national medical insurance of the authors' country does not cover these expenses. This ...
Uchiyama Eduardo E Department of Ophthalmology , Massachusetts Eye and Ear Infirmary, Boston, Massachusetts , USA - - 2014
Abstract Uveitis is a group of inflammatory ocular conditions that cause significant visual morbidity around the world. Many of the cases of blindness secondary to uveitis can be avoided with adequate and aggressive management of the intraocular inflammation. Steroids have been utilized in the treatment of noninfectious uveitis for more ...
Contri Alberto A Department of Veterinary Clinical Sciences, University of Teramo, Viale Crispi 212, 64100, Teramo, - - 2014
Pyometra is one of the most common diseases in intact bitches. The aim of this study was to evaluate the effectiveness of a modified aglepristone protocol for the medical treatment of pyometra in the bitch. Of these, 73 bitches affected by pyometra of different breeds and age (2-14 years old) were ...
Mendell Jerry R JR 1] Center for Gene Therapy, Nationwide Children's Hospital, Columbus, OH, USA [2] Department of Pediatrics, The Ohio State University, Columbus, OH, USA [3] Department of Neurology, The Ohio State University, Columbus, OH, - - 2014
Becker muscular dystrophy (BMD) is a variant of dystrophin deficiency resulting from DMD gene mutations. Phenotype is variable with loss of ambulation in late teenage or late mid-life years. There is currently no treatment for this condition. In this BMD proof-of-principle clinical trial, a potent myostatin antagonist, follistatin (FS), was ...
Takesue Yoshio Y ACTIONs Project Committee of Mycoses Forum, Nittochi Toranomon Building, 1-10-5 Toranomon, Minato-ku, Tokyo, 105-8320, Japan Department of Infection Prevention and Control, Hyogo College of Medicine, 1-1 Mukogawa-cho, Nishinomiya, Hyogo 663-8501, Japan - - 2014
The Mycoses Forum in Japan has developed management bundles for candidaemia to incorporate into bedside practice. The aim of this study was to investigate nationwide compliance with the bundles and their impact on clinical outcomes. Non-neutropenic patients treated with antifungals for candidaemia were surveyed. Bundles consist of nine items to ...
Sung Jin Yong JY Thyroid Center, Daerim St. Mary's Hospital, Department of Radiology, Seoul, Korea, Republic of ; - - 2014
Background and Purpose: The purpose of this study is to validate the generalizability of the efficacy and safety of radiofrequency (RF) ablation for treating autonomously functioning thyroid nodules (AFTN) in a large population multicenter study. Materials and Methods: This study included 44 patients from five institutions who refused or were ...
Monti G G Unità di Terapia Intensiva "Bozza", I° Servizio di Anestesia e Rianimazione, A.O. Niguarda Ca'Granda, Milan, Italy2 Dip. di Scienze della Salute, Università degli Studi di Milano, Ospedale San Paolo, Milan, Italy3 Division of Nephrology-Hypertension, University of California San Diego, San Diego, CA, USA4 Dip. di Scienze della Salute, Università Milano Bicocca, A.O. Niguarda Ca' Granda, Milan, - - 2014
Refractory septic shock (RSS) requiring major vasopressor support is associated with high mortality, especially in Gram--negative infections. The study aim was to describe hemodynamics, organ failure, and clinical outcomes in high--dose vasopressor therapy (HDVT) RSS patients treated with Polymyxin B hemoperfusion (PMX--HP) as rescue therapy. We retrospectively analyzed 52 patients, ...
Lichtblau Mona M Centre for Pulmonary Hypertension, Thoraxklinik of University Hospital Heidelberg, Amalienstrasse 5, 69126, Heidelberg, Germany, - - 2014
Two phosphodiesterase-type 5 (PDE-5) inhibitors, sildenafil and tadalafil, are approved for treatment of pulmonary arterial hypertension (PAH). It has not yet been observed if transition from sildenafil to tadalafil is beneficial in patients suffering from adverse reactions. Aim of this study was to analyze safety and long-term effects in PAH ...
Ohara Masaya M Department of Metabolism, Endocrinology, and Molecular Medicine, Osaka City University Graduate School of Medicine, 1-4-3, Asahi-machi, Abeno-Ku, Osaka, 545-8585, - - 2014
Paget's disease of bone (PDB) is a chronic disorder characterized by localized bone regions with excessive bone turnover. Although oral risedronate (17.5 mg daily for 8 weeks) was recently approved in Japan, its efficacy is not well understood. We retrospectively examined the efficacy of oral risedronate in PDB patients in a clinical ...
Ozkan Feyza Unlu FU Department of Physical Medicine and Rehabilitation, Fatih Sultan Mehmet Education and Research Hospital, E-5 Karayolu İçerenköy-Ataşehir, 34752, İstanbul, Turkey, - - 2014
Ulnar nerve entrapment at the elbow (UNE) is the second most common entrapment neuropathy of the arm. Conservative treatment is the treatment of choice in mild to moderate cases. Elbow splints and avoiding flexion of the involved elbow constitute majority of the conservative treatment; indeed, there is no other non-invasive ...
Broderick Joseph P JP From the Departments of Neurology and Rehabilitation Medicine and Radiology, University of Cincinnati Neuroscience Institute, University of Cincinnati Academic Health Center, Cincinnati (J.P.B., P.K., J.S., J.C., T.A.T.); Department of Public Health Sciences (Y.Y.P, S.D.Y., L.D.F.) and the Division of Emergency Medicine (E.C.J.), Medical University of South Carolina, Charleston; Calgary Stroke Program, Seaman Family MR Research Centre, Departments of Clinical Neurosciences and Radiology, Hotchkiss Brain Institute, University of Calgary, Calgary, AB, Canada (A.M.D., M.D.H., M.G.); Stroke Institute, University of Pittsburgh Medical Center, Pittsburgh (T.G.J.); Melbourne Brain Centre, Royal Melbourne Hospital, University of Melbourne, Melbourne, VIC, Australia (B.Y.); Department of Neuroradiology, Dresden University Stroke Center, University Hospital, Dresden, Germany (R.v.K.); Neurovascular Unit, Department of Neurology, Hospital Universitari Vall d'Hebron, Barcelona (C.A.M.); Department of Neurology, University Medical Center Utrecht and the Rudolph Magnus Institute of Neurosciences, Utrecht, the Netherlands, and the St. Antonius Hospital, Nieuwegein, the Netherlands (W.J.S.); Department of Neurology and Stroke Center, Lariboisière Hospital, Paris (M.M.); Department of Neurology, Basel University Hospital, Basel, Switzerland (S.T.E.); George Institute for Global Health, Royal Prince Alfred Hospital, University of Sydney, Sydney (C.A.); and National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD (L.S.J.). - - 2014
We explored changes in the patient population and practice of endovascular therapy during the course of the Interventional Management of Stroke (IMS) III Trial. Changes in baseline characteristics, use of baseline CT angiography, treatment times and specifics, and outcomes were compared between the first 4 protocols and the fifth and ...
Reineke David D Department of Cardiovascular Surgery, University Hospital Berne, Berne, - - 2014
Objective evaluation of the impact of minimized extracorporeal circulation (MECC) on perioperative cognitive brain function in coronary artery bypass grafting (CABG) by electroencephalogram P300 wave event-related potentials and number connection test (NCT) as metrics of cognitive function. Cognitive brain function was assessed in 31 patients in 2013 with a mean ...
Guglielmetti Lorenzo L Sorbonne Universités, UPMC Univ Paris 06, CR7, Centre d'Immunologie et des Maladies Infectieuses, CIMI, Team E13 (Bactériologie), F-75013, Paris, France INSERM, U1135, Centre d'Immunologie et des Maladies Infectieuses, CIMI, Team E13 (Bactériologie), F-75013, Paris, - - 2014
 Bedaquiline is a new antibiotic that was approved for the treatment of multidrug-resistant (MDR) tuberculosis (TB). We aimed to evaluate the short-term microbiological efficacy and the tolerability profile of bedaquiline.  We performed a retrospective cohort study among MDR-TB patients receiving bedaquiline for compassionate use betweenJanuary 2010 and July 2013 and ...
Lytle Grace G Avedro, Waltham, - - 2014
: Corneal cross-linking (CXL) with ultraviolet-A (UVA) and riboflavin was introduced over 15 years ago and has been widely adopted as a treatment for keratoconus. Several studies have demonstrated the safety and efficacy of the procedure performed according to a standard protocol. Recent scientific and technological advances have highlighted the ...
Begic Amela A aClinic for Nuclear Medicine bClinic for Pulmonology, Clinical Centre, University Hospital of Sarajevo, Sarajevo, Bosnia and Hercegovina cDepartment of Medical Imaging and Physiology, Skane University Hospital and Lund University, Lund, Sweden dDepartment of Experimental and Clinical Medicine, University of Florence, Florence, - - 2014
The aim of the study was to establish whether the duration of anticoagulant (AC) therapy can be tailored, on an objective basis, by using ventilation/perfusion single-photon emission computed tomography (V/P SPECT) and to assess the extent of residual perfusion defects over time. In particular, we addressed the following: (a) is ...
Schou Morten M Herlev University Hospital, Herlev, - - 2014
The optimal duration of a public heart failure (HF) clinic programme is unknown. This substudy of the NT-proBNP stratified follow-up in outpatient heart failure clinics (NorthStar) trial was designed to evaluate the effect of extended follow-up in an outpatient HF clinic on long-term adherence to guideline-based therapy. Patients with HF ...
Wu Boying B Department of Nephrology, The Children's Hospital of Zhejiang University School of Medicine, Hangzhou 310003, China; Department of Pediatrics, Ningbo Yinzhou People's Hospital, Ningbo 315040, - - 2014
The treatment strategy for steroid resistant nephrotic syndrome remains uncertain to present time, especially in those with calcineurin inhibitor resistance or intolerance. To date, few studies have been published using multiple combination therapy of immunosuppressive reagents for children with calcineurin inhibitor resistant or intolerant nephrotic syndrome. 18 consecutive children with ...
Ohtsuka Tsutomu T Department of Dermatology, International University of Health and Welfare Hospital, Nasushiobara, Tochigi, - - 2014
Many patients with atopic dermatitis (AD) are treated with oral cyclosporine or antihistamine therapy in clinical practice. To evaluate the effectiveness of oral cyclosporine and antihistamine therapy on clinical and laboratory findings in patients with AD. Twenty-five patients with AD (male-female = 11 : 14, age 16-42 years old, mean 26.2 years old) were treated with ...
Muñoz García D D Neurology Department, Complejo Hospitalario Universitario de Vigo, Vigo, - - 2014
Uric acid (UA) could act as a natural peroxynitrite scavenger with antioxidant properties. It has been proposed that hyperuricemia might protect against multiple sclerosis (MS). Patients with relapsing-remitting MS starting treatment with interferon beta-1a 44 µg sc 3/week were randomly assigned to receive either inosine 3 g/day or placebo in a double-blind ...
Sarma Nilendu N Department of Dermatology, NRS Medical College, Kolkata, - - 2014
The Papillon-Lefèvre syndrome (PLS) is a rare, autosomal recessive disease that manifests with palmoplantar keratoderma and destructive periodontitis resulting in early onset periodontal breakdown in deciduous and permanent dentition. Management of this condition is difficult. Here we report one 11-year-old consanguineous Muslim boy suffering from PLS. After failing to get ...
Xu Yang Y *Department of Dermatology, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China; †Department of Dermatology, The Second Affiliated Hospital of Nantong University, Nantong, - - 2014
Onychomycosis is difficult to cure. Systemic and topical treatments, including the 1,064-nm Nd:YAG laser, are not very effective when used individually. To compare the efficacy and safety of combined treatment with a long-pulsed 1,064-nm Nd:YAG laser and oral terbinafine with those of either treatment alone. We randomly divided 53 patients ...
Ribero S S Department of Dermatology, University Hospital-Inselspital Bern, University of Bern, Bern, Switzerland; Section of Dermatology, Department of Medical Sciences, University of Turin, Turin, - - 2014
Management of oral lichen planus (OLP) is challenging and therapeutic options are limited. The use of topical tacrolimus has shown promising results. We reviewed our daily life experience with topical tacrolimus in OLP patients. This retrospective unicentre study included all 21 patients with OLP, which were evaluated over a 53-month ...
Vergara Mercedes M Servei de Malalties Digestives, Hospital de Sabadell & Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas (CIBERehd), Parc Tauli s/n, Sabadell, Barcelona, - - 2014
Endoscopic therapy reduces the rebleeding rate and the need for surgery in patients with bleeding peptic ulcers. To determine whether a second procedure improves haemostatic efficacy or patient outcomes or both after epinephrine injection in adults with high-risk bleeding ulcers. For our update in 2014, we searched the following versions ...
Gozdzik J J 1] Department of Clinical Immunology and Transplantation, Polish-American Institute of Pediatrics, Jagiellonian University Medical College, Krakow, Poland [2] Department of Transplantation, Children's University Hospital in Krakow, Krakow, - - 2014
The aim of this study was to analyse the experience of Polish Pediatric Group for Hematopoietic Stem Cell Transplantation in respect to donor lymphocyte infusion procedure. The study included 51 pediatric patients with malignant (45) and non-malignant (6) diseases treated with DLI in the period 1993-2012. The indications for DLI ...
Agarwal Sugandha S Departments of Obstetrics, Gynecology and Newborn Care, The Ottawa Hospital/University of Ottawa, Ottawa, Ontario, - - 2014
A 38-year-old woman was found to have a deep 3.3-cm endometriotic nodule of the bladder, confirmed by cystoscopic resection and imaging. Ultrasound also confirmed a 2.6-cm vaginal fornix implant with similar appearance to the bladder mass. The patient's primary symptoms were mild dysmenorrhea, catamenial dysuria and hematuria. The patient conceived ...
Dobesh Paul P PP University of Nebraska Medical Center, 986045 Nebraska Medical Center, Omaha, NE, 68198-6045, USA, - - 2014
Venous thromboembolism (VTE) is a major cause of morbidity, mortality, and healthcare expenditure. In the United States, approximately 0.1 % of the population experiences an initial VTE event each year. Anticoagulation therapy is the cornerstone of acute VTE treatment and for prevention of recurrent VTE events. Conventional anticoagulants, including heparin, low-molecular-weight ...
El Ghazaly Sherif A SA Orthopedic Surgery Department, Ain Shams University Hospital, Ain Shams University, Cairo, Egypt, - - 2014
Meniscus injuries are the most commonly reported in athletes. Meniscectomy is the most common treatment. Stable peripheral tears may heal, while degenerative tears do well with physical therapy. However, the exact role of physical therapy in treating symptomatic unstable meniscal tears is not known. We aimed to identify the role ...
Herten Monika M Department of Vascular and Endovascular Surgery, University of Münster, Münster, Germany. Electronic address: - - 2014
Although drug-eluting balloons (DEBs) have shown promising results treating de novo (DN) atherosclerotic lesions and appear to have been widely adopted in Europe, their long-term efficacy in the broad spectrum of femoropopliteal restenosis (RE) remains to be proven. The purpose of the study was to assess the efficacy of paclitaxel-DEBs ...
Figueira Eduardo Aleixo EA Federal University of Rio Grande do Norte, Av. Senador Salgado Filho, 1787, Lagoa Nova, Natal, RN, 59056-000, - - 2014
This study aimed to systematically evaluate the long-term results of periodontal tissues in regenerated infrabony and furcation defects. A search of the Medline database was performed (1960 to 2012), complimented by an additional hand search. For inclusion in the review, clinical trials had to include the long-term evaluation of infrabony ...
Rothrock John F JF Department of Neurology, Renown Neurosciences Institute, Reno, NV, - - 2014
To determine whether the utilization of healthcare resources is reduced after chronic migraine patients are treated for 6 months with onabotulinumtoxinA. OnabotulinumtoxinA is indicated for headache prophylaxis in patients with chronic migraine, but its effect on healthcare resource use is unknown. We analyzed data from an open-label study of 230 ...
Glaser D A DA Department of Dermatology, Saint Louis University, St. Louis, MO, - - 2014
Bimatoprost ophthalmic solution 0.03% is approved in several countries for treating eyelash hypotrichosis. Previous trials were limited to 4 months of treatment and primarily idiopathic hypotrichosis. Evaluate long-term safety and efficacy of bimatoprost among subjects with idiopathic or chemotherapy-induced hypotrichosis. This multicentre, double-masked, randomised, parallel-group study included two 6-month treatment ...
Truchuelo M T MT University Ramón y Cajal Hospital, Madrid, Spain. Electronic address: - - 2014
The high rate of relapse of acne lesions following oral isotretinoin treatment is a common problem which remains unsolved. To avoid or minimize relapses, topical retinoids have been used for many years as maintenance treatment. However, adverse effects frequently occur. To determine the efficacy and safety of a new retinoid ...
Piccolo Francesco F Swan District Hospital, Department of Medicine, Perth, Western Australia, Australia ; - - 2014
Rationale: Intrapleural tPA/DNase therapy for pleural infection given at the time of diagnosis has been shown to significantly improve radiological outcomes. Published cases are limited to a single randomized control trial and few case reports only. Objective: Multinational observation series to evaluate the pragmatic "real-life" application of tPA/DNase treatment for ...
Ross S A SA University of Calgary, LMC Endocrinology Centres, Calgary, Alberta, - - 2014
Individuals newly diagnosed with type 2 diabetes commonly have marked hyperglycaemia. We evaluated glucose-lowering treatment strategies with linagliptin and metformin in this prevalent population, for which few dedicated studies of oral antidiabetes drugs have been conducted. Patients (n = 316) diagnosed ≤12 months with HbA1c 8.5-12.0% were randomised 1:1 to double-blind, free-combination treatment ...
Hill Robert H RH 3rd *Plastic Surgery Ohio, The Eye Center of Columbus; †Department of Ophthalmology, The Ohio State University; ‡Section of Oculofacial Plastic and Reconstructive Surgery, Ohio Health Doctors Hospital, Ohio University, Columbus Ohio; §Department of Ophthalmology, Drexel University; and ‖Scheie Eye Institute, University of Pennsylvania, Philadelphia, Pennysylvania, - - 2014
The aim of this study is to investigate whether volumetric enhancement of the infraorbital rim area or, alternatively, of the deep medial cheek, results in greater improvement of tear trough deformity. This prospective, single-blind study recruited 12 patients seeking correction of tear trough deformity. Pretreatment standardized photographs were obtained after ...
Barnes Darryl E DE Department of Orthopedics and Sports Medicine, Mayo Clinic Health System, Austin, MN, - - 2014
Elbow tendinopathy is the most common cause of elbow pain affecting active populations. Surgical excision is reserved for patients with refractory symptoms. Percutaneous ultrasonic tenotomy performed under local anesthesia also removes degenerated tissue and therefore provides an alternative treatment option to surgical excision. This investigation prospectively documented the safety and ...
van Geel N N Department of Dermatology, Ghent University Hospital, Ghent, - - 2014
Depigmentation therapy can be an option in adults with extensive and refractory vitiligo. Remaining pigmented patches can be removed using depigmentation creams (monobenzyl ether of hydroquinone 20%), laser therapy or cryotherapy. In contrast to cream treatment, laser therapy and cryotherapy are fast and targeted methods, capable of destroying melanocytes selectively ...
Petrovic-Lazic Mirjana M Faculty of Special Education and Rehabilitation, University of Belgrade, Belgrade, Serbia; ENT Clinic, Zvezdara Hospital and Clinical Centre, Belgrade, - - 2014
The aim of the study was to assess the effect of endolaryngeal phonomicrosurgery (EPM) and voice therapy in patients with vocal fold polyps using perceptual and acoustic analysis before and after both therapies. The acoustic tests and perceptual evaluation of voice were carried out on 41 female patients with vocal ...
Tristram Amanda A HPV Research Group, School of Medicine, Cardiff University, Cardiff, - - 2014
Vulval intraepithelial neoplasia is a skin disorder affecting the vulva that, if left untreated, can become cancerous. Currently, the standard treatment for patients with vulval intraepithelial neoplasia is surgery, but this approach does not guarantee cure and can be disfiguring, causing physical and psychological problems, particularly in women of reproductive ...
Trad Karim Sami - - 2014
The aim of this randomized, crossover study was to determine if transoral fundoplication (TF) could further improve clinical outcomes in partial responders to high-dose (HD) proton-pump inhibitor (PPI) therapy and to evaluate durability of TF. In seven United States centers, patients with hiatal hernia <=2 cm and abnormal esophageal acid ...
Kennedy N A NA Gastrointestinal Unit, Western General Hospital, Edinburgh, - - 2014
Thiopurines (azathioprine and mercaptopurine) remain integral to most medical strategies for maintaining remission in Crohn's disease (CD) and ulcerative colitis (UC). Indefinite use of these drugs is tempered by long-term risks. While clinical relapse is noted frequently following drug withdrawal, there are few published data on predictive factors. To investigate ...
Huttner Benedikt B VA Salt Lake City Health Care System, IDEAS Center, Salt Lake City, UT 84148, USA Division of Epidemiology, University of Utah, Salt Lake City, UT 84132, - - 2014
To assess rates of starting or stopping antibiotics across different hospitals. We used barcode medication administration data to measure antibiotic use on acute-care wards in 128 Veterans Affairs medical centres (VAMCs) in 2010. A treatment day (TD) was defined as the administration of any antibiotic on a given day. A ...
Del Fresno M Rosa MR Pediatric Rheumatology Unit and - - 2014
Recurrent pericarditis is a troublesome complication of idiopathic acute pericarditis and occurs more frequently in pediatric patients after cardiac surgery (postpericardiotomy syndrome). Conventional treatment with nonsteroidal antiinflammatory drugs, corticosteroids, and colchicine is not always effective or may cause serious adverse effects. There is no consensus, however, on how to proceed ...
Reis Leonardo Oliveira LO Department of Urology, University of Campinas, Unicamp, Campinas, São Paulo, - - 2014
Purpose After a successful pyeloplasty at 3 to 6 months, the question remains whether children need a long follow-up. Methods The medical charts of patients with long-term follow-up (> 5 years), who underwent dismembered pyeloplasty for uretero-pelvic junction obstruction (UPJO) from May 1998 to May 2007, excluding those with bilateral UPJO, solitary ...
Ishikura Kenji K Department of Nephrology, Tokyo Metropolitan Children's Medical Center, 2-8-29 Musashidai, Fuchu, Tokyo, 183-8561, Japan, - - 2014
To investigate the long-term outcome in children with frequently relapsing nephrotic syndrome (FRNS) we conducted a follow-up of a previous randomized controlled trial (RCT) 10 years after the initiation of the treatment protocol. We previously conducted an RCT on the efficacy of cyclosporine for treating children with FRNS. After 2 years of ...
Pereira Vitor Mendes VM Interventional Neuroradiology Unit, Service of Neuroradiology, University Hospitals of Geneva, Geneva, Switzerland Division of Neuroradiology, Department of Medical Imaging, Toronto Western Hospital, University Health Network, Toronto, Ontario, Canada Division of Neurosurgery, Department of Surgery, Toronto Western Hospital, University Health Network, Toronto, Ontario, - - 2014
Flow diverter stents (FDS) have been described as a breakthrough in the treatment of intracranial aneurysms. Of the various flow diverter models, the Pipeline device has been the main approved and used device, with established and good long-term results. To present the first series of patients treated with its new ...
Tan Shu-Tao ST Department of Urology, Shengjing Hospital, China Medical University, China - - 2014
Bleeding stomal varices after ileal conduit urinary diversion are rare, but they can develop in patients with portal venous hypertension caused by cirrhosis. We report the case of a 68-year-old man who developed stomal haemorrhage two months after radical cystectomy and ileal conduit urinary diversion to treat invasive bladder cancer. ...
Batirel Ayse A Infectious Diseases and Clinical Microbiology, Kartal Dr. Lutfi Kirdar Education and Research Hospital, Semsi Denizer Cd. E-5 Karayolu Cevizli Mevkii, 34890 Kartal, Istanbul, Turkey. Electronic address: - - 2014
To compare responses to tenofovir (TDF) and entecavir (ETV) therapy. This was a multicenter retrospective study including treatment-naïve patients with chronic hepatitis B (CHB) who received TDF or ETV. The primary end-points were undetectable HBV-DNA at 48 weeks and serological and biochemical responses. Out of 195 CHB patients, 90 (46%) ...
Maffi Paola P 1 Division of Immunology, Transplantation and Infectious Diseases, Diabetes Research Institute, IRCCS San Raffaele Scientific Institute, Milan, Italy. 2 Department of Surgery, Cell Isolation and Transplantation Center, University of Geneva, Genève, Switzerland. 3 Department of Radiology and Center for Experimental Imaging, IRCCS San Raffaele Scientific Institute, Milan, Italy. 4 Vita-Salute San Raffaele University, Milan, Italy. 5 Correspondence to: Prof. Lorenzo Piemonti, MD, Diabetes Research Institute, San Raffaele Scientific Institute, Via Olgettina 60, 20132 Milan, Antonio Secchi, Vita-Salute San Raffaele University, Via Olgettina 60, 20132 Milan, - - 2014
Our final objective is to develop an adoptive therapy with tolerogenic donor-specific type 1 T regulatory cells for patients with type 1 diabetes undergoing islet transplantation. The achievement of this objective depends on the availability of an immunosuppressive treatment compatible with the survival, function, and expansion of type 1 T ...
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