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Golden Matthew R MR From the *Center for AIDS and STD, University of Washington, Seattle, WA; and †Public Health-Seattle & King County, Seattle, - - 2014
US gonorrhea treatment guidelines recently changed to promote ceftriaxone as first-line therapy. Because ceftriaxone requires intramuscular administration, this could lead some patients to go untreated. We used an arithmetic model to compare the number of persons with gonorrhea who would be successfully treated with continued use of oral therapies versus ...
Macedo P M PM Dermatology Department, Rio de Janeiro State University (Universidade do Estado do Rio de Janeiro), Rio de Janeiro, - - 2014
The first therapeutic choice for the treatment of cutaneous sporotrichosis is oral itraconazole; however, the increase in cases of zoonotic transmission outbreak necessitates a search for effective and safe treatment alternatives. To evaluate a new potassium iodide (KI) posology as an alternative for the treatment of limited cutaneous forms of ...
Lim Henry W HW Multicultural Dermatology Center, Department of Dermatology, Henry Ford Hospital, Detroit, - - 2014
Narrowband UV-B (NB-UV-B) phototherapy is used extensively to treat vitiligo. Afamelanotide, an analogue of α-melanocyte-stimulating hormone, is known to induce tanning of the skin. To evaluate the efficacy and safety of combination therapy for generalized vitiligo consisting of afamelanotide implant and NB-UV-B phototherapy. This study was performed in 2 academic ...
Treister Nathaniel N Division of Oral Medicine and Dentistry, Dana-Farber/Brigham and Women's Cancer Center, Boston, - - 2014
Oral chronic graft-versus-host disease (cGVHD) is a debilitating complication following allogeneic hematopoietic cell transplantation (HCT). The objective of this study was to evaluate the safety and efficacy of intraoral narrow-band UVB (NB-UVB) phototherapy in the management of oral cGVHD. Patients with oral cGVHD were treated using a custom NB-UVB unit ...
Sauer N N Department for Endocrinology and Diabetology, University Hospital Hamburg Eppendorf (UKE), Hamburg, - - 2014
The aim of the work was to investigate whether continuation of treatment, side effects, and effect on weight loss of GLP-1 agonists in obese patients without diabetes are equally promising in daily clinical-practice-settings compared to controlled clinical trials. Obese patients without diabetes of our interdisciplinary obesity centre were treated off-label ...
Yang Xin-Wei XW Centre of Arrhythmia Diagnosis and Treatment, Fuwai Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, No. 167 Beilishi Road, Xicheng District, 100037, Beijing, - - 2014
Abbreviation of paced QRS duration has been taken as electrical resynchronization imposed by cardiac resynchronization therapy (CRT). However, little is known about alteration in native QRS duration and its correlation with therapeutic response as well as anatomical remodeling post-CRT. Data of 74 consecutive patients with complete ECG records were reviewed. ...
Gantner Pierre P From the Le Trait d'Union, Centre de Soins de l'Infection par le VIH, Hôpitaux Universitaires de Strasbourg , Strasbourg , - - 2014
Background: To decrease drug burden among HIV-1-positive adults, we need a new gold standard for antiretroviral therapy maintenance strategies. Methods: This retrospective study aimed to assess efficacy in maintenance strategy of atazanavir (ATV) and raltegravir (RAL) dual therapy. The proportion of patients with HIV-1 RNA < 40 copies/ml at specific ...
Caso Francesco F Research Center of Systemic Autoinflammatory Diseases and Behçet's disease Clinic, Department of Medical Sciences, Surgery and Neurosciences, University of Siena, Siena, - - 2014
Vogt-Koyanagi-Harada disease (VKHD) is a multisystemic disorder characterized by granulomatous panuveitis variably combined with T cell-mediated neurologic and cutaneous manifestations. Early and aggressive treatment with systemic corticosteroids is the mainstay of treatment for VKHD. Additional use of immunosuppressants, intravenous immunoglobulins, and tumor necrosis factor-alpha inhibitors can help the most severely ...
Martos Maider M aDepartment of Gastroenterology, University of Basque Country (UPV/EHU), Centro de Investigación Biomédica en Enfermedades Hepáticas y Digestivas (CIBERehd) bDepartment of Microbiology cDepartment of Epidemiology, CIBERESP, Donostia Hospital, Institute Biodonostia, San Sebastián, - - 2014
Resistance to antibiotics is the major cause of treatment failure of Helicobacter pylori (HP) infection. The culture-guided triple therapy (chosen on the basis of a preliminary in-vitro susceptibility test) might help to increase treatment success in high antibiotic resistance regions. The aim of this study was to evaluate the effectiveness ...
Montenij Leonard - - 2014
Early goal-directed therapy refers to the use of predefined hemodynamic goals to optimize tissue oxygen delivery in critically ill patients. Its application in high-risk abdominal surgery is, however, hindered by safety concerns and practical limitations of perioperative hemodynamic monitoring. Arterial waveform analysis provides an easy, minimally invasive alternative to conventional ...
Park Tina T University of Massachusetts, Worcester, Massachusetts, - - 2014
Acute upper gastrointestinal bleeding is one of the most common medical emergencies. It is important to recognize potential etiologies of upper gastrointestinal bleeding and understand therapeutic modalities available in achieving hemostasis. This article summarizes guidelines in management of acute nonvariceal upper gastrointestinal bleeding and reviews recent advances in the field. ...
Berger M M MM Department of Anesthesiology, Perioperative Medicine and General Intensive Care, UniversityHospital Salzburg and Paracelsus Private Medical University, Salzburg/Austria - - - 2014
Perioperative fluid management plays a fundamental role in maintaining organ perfusion, and is considered to affect morbidity and mortality. Targets according to which fluid therapy should be administered are poorly defined. This systematic review aimed to identify specific targets for perioperative fluid therapy. The PubMed database (January 1993---December 2013) and ...
Aktuglu Zeybek A Cigdem AC Department of Pediatrics, Division of Nutrition and Metabolism, Cerrahpasa Medical Faculty, Istanbul University, Istanbul, Turkiye. - - 2014
Tyrosinemia type 1(HT1) is a chronic disorder leading to severe hepatic, renal and peripheral nerve damage if left untreated. Despite nitisinone treatment HT1still carries the risks of hepatocellular carcinoma and neuropsychological outcomes. A retrospective single center study was carried out based on the phenotype, therapy and outcome in 38 Turkish ...
Hibino Satoshi S Pediatric Nephrology Aichi Children's Health and Medical Center, Aichi, - - 2014
This retrospective study was performed to assess the three-year outcome of a unified protocol for childhood idiopathic nephrotic syndrome. Cyclosporine A (CsA) or CsA plus mycophenolate mofetil (MMF) were administered in cases without remission on high-dose steroid therapy.CsA was maintained at an area under the whole blood concentration-time curve up ...
Yang Woo-Young WY *ENT Department, James Cook University Hospital, Middlesbrough; and †ENT Department Darlington Memorial Hospital, Darlington County, Durham, United - - 2014
To study the long-term recurrence rate of cholesteatoma with autoclaved incus autograft. Prospective observational study between 1994 and 2009. The incus remnants were autoclaved at 134°C for 24 minutes at 205 kPa. The mean follow-up duration was 65.5 months, with a minimum follow-up duration of 31 months and a maximum ...
Tian Simon Yu SY From the Institute of Medical Science, Faculty of Medicine, University of Toronto; Division of Rheumatology and Program of Child Health Evaluative Sciences, The Hospital for Sick Children; Department of Pediatrics, Faculty of Medicine, University of Toronto; Institute of Health Policy, Management and Evaluation, University of Toronto, Toronto; Program in Population Genomics, Department of Clinical Epidemiology and Biostatistics, Faculty of Health Sciences, McMaster University, Hamilton; Dalla Lana School of Public Health, Faculty of Medicine, University of Toronto, Toronto; Cancer Care Ontario, Toronto; Hospital Library, The Hospital for Sick Children, Toronto, Ontario, Canada. S.Y. Tian's PhD research is funded in part by the Queen Elizabeth II-Edward Dunlop Foundation Scholarships in Science and Technology, administered at the University of Toronto. S.Y. Tian, MB, MSc, PhD (C), Institute of Medical Science, Faculty of Medicine, University of Toronto, and The Hospital for Sick Children; B.M. Feldman, MD, MSc, FRCPC, Professor, Institute of Health Policy, Management and Evaluation, University of Toronto, and The Hospital for Sick Children; J. Beyene, PhD, Associate Professor, Program in Population Genomics, Department of Clinical Epidemiology and Biostatistics, Faculty of Health Sciences, McMaster University, and Dalla Lana School of Public Health, Faculty of Medicine, University of Toronto; P.E. Brown, PhD, Associate Professor, Cancer Care Ontario, and Dalla Lana School of Public Health, Faculty of Medicine, University of Toronto, Program in Population Genomics, Department of Clinical Epidemiology and Biostatistics, Faculty of Health Sciences, McMaster University; E.M. Uleryk, MLS, Hospital Library, The Hospital for Sick Children; E.D. Silverman, MD, FRCPC, Professor, Division of Rheumatology and Program of Child Health Evaluative Sciences, The Hospital for Sick Children, and Institute of Medical Science, Department of Pediatrics, and Department of Immunology, University of Toronto. Address correspondence to Dr. E.D. Silverman, Division of Rheumatology, The Hospital for Sick Children, 555 University Ave., Toronto, Ontario M5G 1X8, Canada. E-mail: earl.silverman@sickkids.ca. Accepted for publication April 11, - - 2014
To evaluate and determine the most effective immunosuppressive therapy for the induction treatment of proliferative lupus nephritis (PLN) based on renal remission. A systematic review of randomized controlled trials was conducted. The outcomes were renal remission at 6 months: (1) normalization of serum creatinine [(sCr), or within 15% of the ...
Courrier Vincent V Département Universitaire de Médecine Générale, Faculté de Médecine, Université de Toulouse, Toulouse, - - 2014
Using parenteral anticoagulants in compliance with their summaries of product characteristics (SPCs) and consensus guidelines is associated with decreased rates of adverse drug reactions. The objectives were to assess compliance of parenteral anticoagulants use with SPCs and 4 consensus guidelines in outpatients of general practice. A descriptive cross-sectional study was ...
Peng Kevin A KA Department of Head and Neck Surgery, David Geffen School of Medicine at UCLA, Los Angeles, California, - - 2014
This study aimed to describe management of esophageal stenosis after chemoradiation therapy for head and neck squamous cell carcinoma (HNSCC), with particular emphasis on techniques and outcomes with the use of the transnasal esophagoscope (TNE) in the office as well as operating room settings. Retrospective analysis of all patients with ...
Nanto Kiyonori K Cardiovascular Center, Kansai Rosai Hospital, Amagasaki, Japan - - 2014
Efficacy of endovascular therapy (EVT) with nitinol stents for femoropopliteal (FP) lesions is limited by restenosis. Oral cilostazol reduces angiographic restenosis rate; however, treatment duration remains unclear. In a retrospective analysis of a multicenter database of 3471 consecutive limbs in 2737 patients (mean age: 72 ± 9 years; 61% diabetic; ...
Debu A A Department of Dermatology, INSERM 1058, University of Montpellier I, Montpellier, - - 2014
A 72-year-old man with a 40-year history of discoid lupus erythematosus (DLE) localised on the face had been treated for 20 years with topical corticosteroids, tacrolimus and systemic therapies including chloroquine and hydroxychloroquine, withdrawn because of irreversible retinopathy. Thalidomide treatment lasted almost 2 years but was stopped because of peripheral ...
Kim Yang-Soo YS Department of Orthopaedic Surgery, Seoul St. Mary's Hospital, The Catholic University of Korea, Seoul, South - - 2014
Ultrasound (US)-guided needling with subacromial corticosteroid injection is more effective than extracorporeal shock wave therapy (ESWT) for function restoration and pain relief in patients with calcific tendinitis of the shoulder. Fifty-four patients diagnosed with unilateral painful calcific tendinitis were randomly allocated to a US needling or ESWT group. The US ...
Zhang Qingqiao Q Department of Interventional Radiology and Vascular Surgery, The Affiliated Hospital of Xuzhou Medical College, No. 99 Huaihai West Road, Xuzhou, 221006, Jiangsu province, China, - - 2014
This study was designed to investigate the safety and efficacy of endovascular intervention for the treatment of primary entire-inferior vena cava (IVC) occlusion. Endovascular interventions were performed in six patients for the treatment of primary entire-IVC occlusion. IVC and hepatic venography were performed via the jugular and femoral veins. Balloon ...
Bachmann Alexander A Department of Urology Basel, University Hospital Basel, University Basel, Basel, Switzerland. Electronic address: - - 2014
We present the one year results of the GOLIATH prospective randomized control trial comparing TURP to GreenLight-XPS (GL-XPS) for the treatment of men with non-neurogenic lower urinary tract symptoms due to prostate enlargement. The updated results at one year show that TURP and GL-XPS remain equivalent and confirm therapeutic durability ...
Veraldi Stefano S Department of Pathophysiology and Transplantation, University of Milan, IRCCS Foundation Cà Granda, Ospedale Maggiore Policlinico, Milan, - - 2014
Background: There is no established therapy of choice for Mycobacterium marinum skin infections; clarithromycin monotherapy was used in some anecdotical cases at changeable daily doses and length. Objective: To evaluate the efficacy and safety of pulsed clarithromycin monotherapy. Methods: 29 patients with a clinical diagnosis of sporotrichoid fish tank granuloma ...
Beuth Josef J Institute for Naturopathy, University of Cologne, Cologne, Germany - - 2014
Aim: The present clinical investigation was performed to evaluate the benefits of complementary medicine in prostate cancer patients undergoing hormone therapy (HT). Patients and Methods: Patients (N=93) were treated according to international guidelines. All patients suffered from side-effects induced by the HT. To reduce the side-effects, the patients were complementarily ...
Ren Ling L Department of Gastroenterology, The First People's Hospital of Lianyungang, Lianyungang, Jiangsu Province, - - 2014
To evaluate the eradication rates, side effects and the compliance of patients of a dual therapy with rabeprazol and amoxicillin in different doses as the first-line therapy in patients with Helicobacter pylori (H. pylori) infection. One hundred and twenty patients who were diagnosed with non-ulcer dyspepsia with H. pylori infection ...
Tselios K K Clinical Immunology Unit, 2nd Department of Internal Medicine, Hippokration General Hospital, Aristotle University of Thessaloniki , - - 2014
Objectives: Regulatory T cells (Tregs) are inversely correlated to disease activity in systemic lupus erythematosus (SLE). However, little is known concerning the influence of immunosuppressive agents on Tregs, which was the objective of this study. Method: Thirty-five patients with SLE (29 females, six males, mean age 42.4 ± 12.8 years) ...
Zhu Meidong M Sydney Institute of Vision Science, Level 13, 187 Macquarie Street, Sydney, 2000, - - 2014
Intravitreal anti-vascular endothelial growth factor (anti-VEGF) agents are the established standard of care for neovascular age-related macular degeneration (nAMD). However, data on long-term outcomes of this therapy are limited. The purpose of this study was to assess the visual and anatomical outcomes and safety profile of intravitreal ranibizumab in treating ...
Park Sang Ho - - 2014
There have been few randomized control trials comparing the incidence of stent fracture and primary patency among different self-expanding nitinol stents to date. The SMARTTM CONTROL stent (Cordis Corp, Miami Lakes, Florida, United States) has a peak-to-valley bridge and inline interconnection, whereas the COMPLETETM-SE stent (Medtronic Vascular, Santa Rosa, California, ...
Sjöblom J J Division of Cardiovascular Medicine, Department of Clinical Sciences, Karolinska Institutet, Danderyds Hospital, Danderyd University Hospital, 18288 Stockholm, Sweden - - 2014
International guidelines advocate an implantable cardioverter and defibrillator (ICD) in patients with reduced left ventricular ejection fraction (LVEF) to prevent sudden death (SCD). Previous data suggest that the benefit of ICD therapy in real life may be lower than expected from the results of controlled studies and side-effects are not ...
Mok Zhun-Rui ZR Department of Medicine, National University Health System, - - 2014
The goal of the current study was to review a cohort of Asian children with atopic dermatitis (AD) treated using phototherapy at a tertiary dermatologic center in Singapore. We performed a retrospective review of patients younger than 16 years old with a clinical diagnosis of AD treated with phototherapy at the ...
Bluett James J Arthritis Research UK Centre for Genetics and Genomics, University of Manchester, National Institute of Health Research Manchester Musculoskeletal Biomedical Research Unit, Central Manchester Foundation Trust and University of Manchester, Manchester Academic Health Science, Arthritis Research UK Centre for Epidemiology, University of Manchester, Manchester, Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds, National Institute of Health Research Leeds Musculoskeletal Biomedical Research Unit, Leeds, Academic Unit of Rheumatology, Department of Infection and Immunity, University of Sheffield Medical School, Sheffield, Musculoskeletal Research Group, Institute of Cellular Medicine, Newcastle University and National Institute of Health Research Newcastle Biomedical Research Centre, Newcastle upon Tyne and Institute for Inflammation and Repair, University of Manchester, Manchester, - - 2014
Non-adherence to DMARDs is common, but little is known about adherence to biologic therapies and its relationship to treatment response. The purpose of this study was to investigate the association between self-reported non-adherence to s.c. anti-TNF therapy and response in individuals with RA. Participants about to start s.c. anti-TNF therapy ...
Yang Fang F Department of Neurology, Xijing Hospital, No. 15 West Changle Road, Xi'an, 710032, China, - - 2014
Nondisabling cerebrovascular events represent the largest group of cerebrovascular disease with a high risk of recurrent stroke. A recent trial demonstrated that dual-antiplatelet therapy (clopidogrel and aspirin), compared with aspirin monotherapy, reduced the risk of recurrent stroke and was not associated with increased risk of hemorrhagic events. Apixaban, a new ...
Konno Mutsuko M Department of Pediatrics, Sapporo Kosei General Hospital, Sapporo, - - 2014
Long-term effectiveness of enteral nutrition for maintaining remission in pediatric Crohn's disease is poorly documented. Therefore we examined the long-term effect of enteral nutrition with aminosalycylates as maintenance therapy for those in whom remission was primarily induced by total parenteral nutrition or exclusive enteral nutrition with aminosalicylates. We retrospectively analyzed ...
Konrad Torsten T II. Medical Clinic, Department of Electrophysiology, Johannes Gutenberg University Mainz, Langenbeckstr. 1, 55131, Mainz, Germany, - - 2014
Techniques facilitating individual mapping and ablation of arrhythmogenic substrates are desired to enhance our understanding of persistent atrial fibrillation (persAF) mechanisms as a prerequisite to increasing the success rates of single procedure persAF catheter ablation. The technique of body surface potential mapping (BSM) involves the use of multiple electrodes to ...
Nunn Andrew J - - 2014
In contrast to drug-sensitive tuberculosis, the guidelines for the treatment of multi-drug-resistant tuberculosis (MDR-TB) have a very poor evidence base; current recommendations, based on expert opinion, are that patients should be treated for a minimum of 20 months. A series of cohort studies conducted in Bangladesh identified a nine-month regimen ...
Dauerman Harold L HL University of Vermont College of Medicine, Burlington, VT - - 2014
In this issue of Circulation, the 3 year follow up of the PARTNER B trial provides us with a sobering final word on the natural history of severe aortic stenosis(1). As described 50 years ago, severe aortic stenosis is a terminal illness of the elderly with a progression from symptoms ...
Martínez García Laura L Iberoamerican Cochrane Centre and Biomedical Research Institute Sant Pau (IIB Sant Pau) (García, Sanabria, Rigau, Barajas-Nava, Solà, Alonso-Coello), Barcelona, Spain; NHS Ayrshire and Arran (García Álvarez), Ayr, United Kingdom; Fundacion Canaria de Investigacion y Salud (FUNCIS), Red de Investigacion en Servicios de Salud en Enfermedades Cronicas (REDISSEC) (Trujillo-Martín), Tenerife, Spain; Osteba, and Basque Office for Health Technology Assessment (Etxeandia-Ikobaltzeta), Vitoria, Spain; Agency for Health Quality and Assessment of Catalonia (AQuAS) (Kotzeva, Estrada), Barcelona, Spain; CIBER of Epidemiology and Public Health (CIBERESP) (Kotzeva, Estrada, Solà, Alonso-Coello), Barcelona, Spain; Centro de Saude de Cambre, Xerencia de Xestion Integrada de A Coruna SERGAS (Louro-González), A Coruna, Spain; Health Technology Assessment Unit (UETS), Subdireccion General de Tecnología e Innovacion Sanitaria, Consejería de Sanidad (Díaz del Campo), Madrid, Spain; National Clinical Practice Guideline Programme of the NHS (Gracia), Madrid, Spain; GuíaSalud-Aragon Institute of Health Sciences (Salcedo -Fernandez), Zaragoza, Spain; Department of Clinical Epidemiology and Biostatistics, McMaster University, (Lawson, Haynes), Hamilton, - - 2014
Clinical guidelines should be updated to maintain their validity. Our aim was to estimate the length of time before recommendations become outdated. We used a retrospective cohort design and included recommendations from clinical guidelines developed in the Spanish National Health System clinical guideline program since 2008. We performed a descriptive ...
Brümmendorf Tim H TH Universitätsklinikum Aachen, RWTH Aachen, Aachen, Germany; Universitätsklinikum Hamburg-Eppendorf, Hamburg, - - 2014
Bosutinib is an oral, dual SRC/ABL1 tyrosine kinase inhibitor for resistant/intolerant chronic myeloid leukaemia (CML). We assessed the efficacy and safety of bosutinib 500 mg/d (n = 250) versus imatinib 400 mg/d (n = 252) after >24 months from accrual completion in newly diagnosed chronic phase (CP)-CML (Bosutinib Efficacy and Safety in Newly Diagnosed CML trial [BELA]). ...
Iung Bernard B Cardiology Department, AP-HP, Bichat Hospital, 46 rue Henri Huchard, 75018, Paris, France Paris-Diderot University, DHU Fire, Paris, France bernard.iung@bch.aphp.fr - - 2014
Anti-thrombotic therapy after valve replacement encompasses a number of different situations. Long-term anticoagulation of mechanical prostheses uses vitamin K antagonists with a target international normalized ratio adapted to the characteristics of the prosthesis and the patient. The association of low-dose aspirin is systematic in the American guidelines and more restrictive ...
Benoit R M RM Department of Urology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA. Electronic address: - - 2014
To report 5 year prostate-specific antigen outcomes in men undergoing prostate brachytherapy with caesium 131 at a single institution. All patients who underwent prostate brachytherapy with caesium 131 at our institution and had at least 24 months of follow-up were included in this study. The results are reported by risk ...
Rayess Nadim N Retina Service of Wills Eye Hospital, Mid Atlantic Retina, Philadelphia, - - 2014
To determine three year treatment outcomes after 1 to 3 years of ranibizumab or bevacizumab therapy using a "treat and extend" regimen for patients with neovascular age-related macular degeneration (AMD). Retrospective, interventional, consecutive case series. 212 eyes from 196 patients diagnosed with treatment naïve neovascular AMD between January 2009 till ...
Zarranz-Ventura Javier J Bristol Eye Hospital, Bristol, United Kingdom; Gloucestershire Hospitals National Health Service Trust, Cheltenham, United Kingdom; Institut Clínic d´Oftalmologia (ICOF), Hospital Clínic, Barcelona, Spain. Electronic address: - - 2014
To identify clinical outcomes and treatment patterns of intravitreal dexamethasone implant (Ozurdex®) in non-infectious uveitis in the clinical setting. Multicenter retrospective cohort study. 82 eyes (63 patients) receiving 142 implant injections over 35 months were included. Treatment indication, uveitis diagnosis, visual acuity, intraocular pressure, vitreous haze score, central retinal thickness ...
Mesquida Marina M Institut Clinic d'Oftalmologia, Hospital Clínic de Barcelona, Universitat de Barcelona, Barcelona, - - 2014
To report the long-term efficacy and safety of the interleukin-6 receptor antagonist tocilizumab for refractory uveitis-related macular edema (ME). Retrospective cohort study. Eyes with uveitis seen at a single tertiary referral center for which ME was the principal cause of reduced visual acuity. Data were obtained by standardized chart review. ...
Gajofatto Alberto A Department of Neurological and Movement Sciences, University of Verona, Verona, - - 2014
Background: It is unclear whether natalizumab and fingolimod have analogous efficacy for relapsing-remitting multiple sclerosis (RRMS). Objective: To compare the outcome of RRMS patients treated with either therapy. Methods: RRMS patients treated with natalizumab or fingolimod at Verona Hospital, Italy, were included. The study design was retrospective, based on prospectively ...
Durão Ana Reis AR a Invited Assistant, Department of Dental Radiology, Faculty of Dental Medicine, University of Porto, - - 2014
Objective: To evaluate the impact of additional lateral cephalometric radiography in orthodontic diagnosis and treatment planning. Materials and Methods: Forty-three patients seeking orthodontic treatment, and for whom pretreatment diagnostic records were available, were randomly selected. Ten qualified orthodontists were involved in this study. The patients' records included three photographs of ...
Holz Frank G FG Department of Ophthalmology, University of Bonn, Bonn, - - 2014
Real-life anti-vascular endothelial growth factor (VEGF) therapy use in patients with wet age-related macular degeneration (wAMD) was assessed in a retrospective, observational study in Canada, France, Germany, Ireland, Italy, the Netherlands, UK and Venezuela. Medical records of patients with wAMD, who started ranibizumab treatment between 1 January 2009 and 31 ...
Casale Maddalena M Dipartimento della Donna, del Bambino e di Chirurgia Generale e Specialistica, Second University of Naples, Naples, - - 2014
Iron overload in β-thalassemia major typically results in iron-induced cardiomyopathy, liver disease and endocrine complications. We examined the incidence and progression of endocrine disorders (hypothyroidism, diabetes, hypoparathyroidism, hypogonadism), growth and pubertal delay, and bone metabolism disease during long-term deferasirox chelation therapy in a real clinical practice setting. We report a ...
Türko─člu E B EB Akdeniz University, Department of Ophthalmology, 07100 Antalya, Turkey. Electronic address: - - 2014
To compare the outcomes in the management of traumatic hyphema treated with topical corticosteroid plus supportive therapy versus only supportive therapy. In this retrospective study, 206 patients were divided into two groups; group I, 98 eyes were treated with topical corticosteroid 12×1 and supportive therapy including bed rest, keeping the head elevated (45 degrees), ...
Siewe Jan - - 2014
The 360[degree sign] fusion of lumbar segments is a common and well-researched therapy to treat various diseases of the spine. But it changes the biomechanics of the spine and may cause adjacent segment disease (ASD). Among the many techniques developed to avoid this complication, one appears promising. It combines a ...
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