Search Results
Results 401 - 450 of 2611
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Zaiac Martin - - 2011
Actinic cheilitis (AC), a common disorder of the lower lip, should be treated early to prevent progression to invasive squamous cell carcinoma. This study evaluated the safety and efficacy of photodynamic therapy (PDT) with 5-aminolevulinic acid (ALA) activated by blue light for the treatment of AC. Fifteen patients with clinically ...
Wen Jian Guo - - 2011
Objective: To summarize the clinical features and follow-up, the effects of melamine-tainted milk powder (MMP) consumption on kidney and body growth in children who suffered from melamine-related urinary stones (MUS) 2 years earlier were checked. Measurements: Body height and weight, kidney and bladder morphology monitored by ultrasound, urinalysis and renal ...
Crespi Roberto - - 2011
The aim of this study was to compare modified Widman flap surgery (MW) to coronally advanced flap surgery combined with carbon dioxide laser root conditioning (CAF + CO2) from baseline to 15 years of follow-up. Each of 25 patients participating in this study were treated using a split-mouth design: In ...
Franqueira Nuno - - 2011
Purpose: To evaluate the long-term safety and efficacy of intravitreal ranibizumab in the treatment of myopic choroidal neovascularization (CNV). Methods: Three-year retrospective, nonrandomized, interventional case series. Forty eyes of 39 patients with myopic CNV were included; 15 with previous photodynamic therapy, and 25 naïve eyes. Best-corrected visual acuity (BCVA) changes, ...
Chana R - - 2011
We evaluated the safety and efficacy of total knee replacement in patients receiving continuous warfarin therapy. We identified 24 consecutive patients receiving long-term warfarin therapy who underwent total knee replacement between 2006 and 2008 and compared them with a group of age- and gender-matched patients not on long-term anticoagulation. Primary ...
Hirdes Meike Madeleine Catharine - - 2011
The use of stents for esophageal strictures has evolved rapidly over the past 10 years, from rigid plastic tubes to flexible self-expanding metal (SEMS), plastic (SEPS) and biodegradable stents. For the palliative treatment of malignant dysphagia both SEMS and SEPS effectively provide a rapid relief of dysphagia. SEMS are preferred ...
Muir Andrew J - - 2011
Retreatment with peginterferon alpha and ribavirin (PR) offers a limited chance of sustained virologic response (SVR) in patients who did not achieve SVR with prior PR treatment. This study evaluated the safety and efficacy of telaprevir-based treatment in combination with PR in well-characterized patients who did not achieve SVR in ...
Scherzer Thomas-Matthias - - 2011
The IL28B genotype is the most important pretreatment predictor of treatment outcome in patients with chronic hepatitis C. The impact of the rs12979860 genotype on relapse was retrospectively evaluated in genotype 1/4 patients who received response-guided therapy with peginterferon alpha-2a 180 μg/week plus ribavirin 1,000/1,200 mg/day in a large, randomized, ...
Liaw Y-F - - 2011
As there is currently a lack of consensus on the most appropriate dose and duration of peginterferon alfa-2a (PEG-IFNα-2a) therapy in hepatitis B e antigen (HBeAg)-positive patients, the efficacy and safety of either 24 or 48 weeks' duration and 90 μg/week or 180 μg/week doses were compared. HBeAg-positive patients (n ...
Chen Ling - - 2011
To compare the visual outcomes and retreatment rates of monotherapy with intravitreal bevacizumab versus combination with photodynamic therapy for choroidal neovascularization secondary to causes other than age-related macular degeneration. Seventeen patients received intravitreal bevacizumab, and 6 patients underwent intravitreal bevacizumab combined with verteporfin photodynamic therapy within 3 days. Additional bevacizumab ...
Vorkas Charles K - - 2012
Evaluating treatment failure is critical when deciding to modify antiretroviral therapy (ART). Virologic Assessment Forms (VAFs) were implemented in July 2008 as a prerequisite for ordering viral load. The form requires assessment of clinical and immunologic status. Using the Electronic Medical Record (EMR), we retrospectively evaluated patients who met 2006 ...
Hufnagel Andreas - - 2011
Most patients with epilepsy require long-term medical therapy. Newer antiepileptic drugs (AEDs) appear to be overall similarly effective to older agents but may be better tolerated. However, most of the clinical data available for newer AEDs derive from a number of short-term studies. The objective of this study was to ...
Anavekar Nandan S NS Division of Cardiovascular Diseases, Mayo Clinic, 200 First St SW, Rochester, MN 55905, USA. - - 2011
To ascertain the impact of prior antiplatelet and statin therapy on symptomatic embolic events in [corrected] infective endocarditis (IE). We studied a retrospective cohort of adult patients with a diagnosis of IE who presented to Mayo Clinic (Rochester, MN) from January 1, 2003, to December 31, 2006. Patients were grouped ...
Casotti Janaina Aparecida Schineider JA Infectious Diseases Outpatient Clinic, Cassiano Antonio de Moraes University Hospital, Federal University of Espírito Santo, Vitória, Espírito Santo, Brazil. - - 2011
Some patients under antiretroviral therapy (ART) do not reach immune recovery when the viral load becomes undetectable. This is called discordant immunologic and virologic responses. Its prevalence varies between 8% and 24%. This study describes its prevalence and the characteristics of the affected subjects in the outpatient clinic of a ...
Beltrami Laura L Fondazione Salvatore Maugeri, Istituto Scientifico di Milano, IRCCS, Milan, - - 2011
To investigate, for the first time, the frequency of recurrences of angiotensin-converting enzyme inhibitor (ACE-I)-related angioedema after the discontinuation of ACE-I. This retrospective study was conducted in an outpatient tertiary-level centre for a total period of 173 months (about 14 years). Consecutive patients with recurrent angioedema symptoms, initiated during treatment ...
Zhang Qiaoyi Q Global Health Outcomes, Merck Sharp and Dohme Corp, Whitehouse Station, NJ 08889, USA. - - 2011
To compare compliance and persistence with statin and oral antihyperglycemic therapies in patients with type 2 diabetes who received concomitant therapy. Retrospective cohort study using a large US commercial claims database. Patients with type 2 diabetes and dispensed prescriptions for both statin and oral antihyperglycemic therapies on the same date ...
Samonis G - - 2011
Combination antimicrobial therapy represents common practice in the treatment of febrile neutropenia aiming to broaden the antimicrobial spectrum against Gram-negative pathogens. We did a prospective, non-randomized, comparative study to evaluate ceftazidime plus either levofloxacin or once-daily amikacin as empirical regimens for febrile neutropenia in patients with solid tumor or hematopoietic ...
Xiao Li - - 2012
To determine the treatment response and disease progression in strictly selected patients with myelodysplastic syndrome undergoing immunosuppressive therapy (IST), patients were required to have an international prognostic scoring system [corrected] (IPSS) score ≤ 1.0 and at least one of the following conditions: (1) expression of the HLA-DR15 allele, (2) bone ...
Takinami Yoshikazu - - 2011
Abstract Conclusion: A stellate ganglion block (SGB) based on the goal of improving internal ear circulatory disturbance appears to be beneficial for the treatment of sudden hearing loss. Objectives: To evaluate the effectiveness of SGB for sudden hearing loss. Methods: This retrospective study reviewed the medical records of 49 patients ...
Valentín Antonio - - 2011
BACKGROUND: Refractory status epilepticus (RSE) is associated with high mortality. We report a potential treatment alternative. HYPOTHESIS: Deep brain stimulation (DBS) of the centromedian thalamic nuclei (CMN) can be effective in the treatment of RSE. METHODS: Report of the evolution of RSE after DBS of the CMN in a 27-year-old ...
Sato Edson S - - 2012
The aim of this study is to evaluate the effectiveness of CS injection, percutaneous pulley release and conventional open surgery for treating trigger finger in terms of cure, relapse and complication rates. One hundred and thirty-seven patients with a total of 150 fingers were randomly assigned and allocated into one ...
Pini Rodolfo - - 2011
INTRODUCTION: Chronic oral anticoagulant therapy (OAT) is of widespread use, and usually its management in patients undergoing carotid artery stenting (CAS) is through perioperative bridging heparin therapy. Aim of the present study is to analyze a single center experience of CAS in patients maintaining OAT without perioperative bridging heparin therapy. ...
Dizdarevic Kemal - - 2011
PURPOSE: Secondary brain ischaemia (SBI) usually develops after aneurysmal subarachnoid haemorrhage (SAH) and severe traumatic brain injury (TBI). Current approaches to managing these conditions are based either on intracranial pressure-targeted therapy (ICP-targeted) with cerebral microdialysis (CM) monitoring according to the modified Lund concept or cerebral perfusion pressure-targeted therapy (CPP-targeted). We ...
Rivas R - - 2011
OBJECTIVE: To describe the use and effectiveness of linezolid as an alternative treatment for methicillin-resistant Staphylococcus aureus. METHOD: Demographic, clinical and safety data were collected from hospitalised patients. The information sources were the clinical records and the pharmacy programme. RESULTS: Thirty patients were treated with linezolid (median age 69.3, 63% ...
Wray Sibyl - - 2011
Background: Patients with multiple sclerosis (MS) often receive long-term injectable therapy, and difficulties associated with self-injection can affect treatment adherence and efficacy. Objective: The objective of this study was to evaluate an investigational, ready-to-use, single-use autoinjector for self-injection of subcutaneous (sc) interferon beta-1a (IFNβ-1a). Methods: In this multicenter, open-label, single-arm ...
Nagel Robyn - - 2011
Background: Blastocystis is a common, enteric parasite. The pathogenicity of the organism is uncertain but subtypes (ST) 1,3 have been reported more likely to cause Irritable Bowel-like symptoms. Aims: We treated symptomatic patients positive for Blastocystis (BSP) with conventional therapy and analysed 16SSU rDNA to assess clearance and carriage rates ...
Léger Juliane - - 2011
Context:Drug-based therapy is usually the initial treatment for Graves' disease (GD) hyperthyroidism in children, but there is some debate about treatment duration.Objective:Our objective was to assess the effect of long-term carbimazole therapy on GD remission in children and its determinants.Design and Setting:This was an observational prospective multicenter follow-up cohort study.Participants:Participants ...
Lin Zhong-Jie - - 2011
Abstract Purpose: The aim of this study was to assess the intraoperative application of mitomycin C (MMC) compared to 5-fluorouracil (5-FU) on the outcome of trabeculectomy and to examine the balance of risk and benefit. Methods: Pertinent studies were selected through systematic searches of major literature databases, including the Cochrane ...
Manzoni Gian Camillo - - 2011
In the field of so-called chronic daily headache, it is not easy for migraine that worsens progressively until it becomes daily or almost daily to find a precise and universally recognized place within the current international headache classification systems. In line with the 2006 revision of the second edition of ...
Kim Soon Sun - - 2012
This study evaluated the efficacy of adefovir (ADV) plus lamivudine (LAM) or ADV add-on therapy for patients with entecavir (ETV)-refractory hepatitis B infection. Twenty-nine ETV-resistant and 8 patients with suboptimal response to ETV were enrolled. Twenty-seven patients received ADV + LAM therapy and 10 patients received ADV + ETV therapy for >24 weeks. In ...
Papp K - - 2012
Adalimumab is an effective treatment for chronic plaque psoriasis. To evaluate the safety and efficacy of adalimumab for psoriasis patients who did not adequately respond to prior psoriasis therapy. PRIDE (an Open-Label Access PRogram to Evaluate the Safety and Effectiveness of Adalimumab When Added to InaDEquate Therapy for the Treatment ...
Hedblad Mari-Anne - - 2011
BACKGROUND: Lentigo maligna (LM) is the in situ phase of lentigo maligna melanoma (LMM). A wide variety of modalities has been used to manage LM, including conventional surgery, staged excision, Mohs micrographic surgery, cryotherapy, radiotherapy, laser therapy, and, recently, imiquimod. OBJECTIVES: Soft x-radiation is an accepted treatment for LM/LMM. The ...
Abern Michael R - - 2011
Introduction.  There is no current consensus as to the most effective nonsurgical therapy for Peyronie's disease (PD). Aim.  This study aims to assess the benefit of penile traction therapy (PTT) when added to intralesional verapamil injections (IVIs) combined with oral L-arginine 1 g b.i.d. and pentoxifylline 400 mg t.i.d. in men with ...
Hsiao S-H - - 2011
What is known and Objective:  Teicoplanin and vancomycin show similar clinical and bacteriological efficacy in clinical trials. Teicoplanin has been reported to have a lower adverse drug reaction (ADR) rate than vancomycin. Cross-reactivity between these two glycopeptides is controversial. Our aim was to study the cross-reactivity between teicoplanin and vancomycin ...
Wessler Jeffrey D - - 2012
For patients requiring surgery within their first year following coronary stent placement, maximizing the prevention of stent thrombosis with antiplatelet therapy while minimizing the risk of intraoperative bleeding has become a management challenge for cardiologists, surgeons and anesthesiologists. In this manuscript, we describe a case of a patient who received ...
Gisbert J P - - 2011
Background  A decrease in the Helicobacter pylori eradication rate after standard triple therapy has been suggested in recent years. Aim  To assess the efficacy of standard triple therapy in the eradication of H. pylori through an epidemiological analysis of all published Spanish trials. A secondary aim was to review the ...
Rordorf Roberto - - 2011
Catheter ablation has been proven to be an effective treatment for patients with drug-resistant atrial fibrillation. Nevertheless its efficacy is limited to 60-80% of patients in different studies. Whether the use of pharmacological therapy after catheter ablation of atrial fibrillation might increase the procedural success rate is still a matter ...
Muñoz Patricia - - 2011
OBJECTIVES: To analyze the incidence trend of listeriosis, its present epidemiology and the potential benefit of aminoglycosides during the last two decades. METHODS: We reviewed all cases of invasive listeriosis detected during a 22-year period in a large tertiary hospital. Two equal periods of 11 years were compared. RESULTS: We ...
Malaguarnera Michele M Department of Biological Chemistry, Medical Chemistry and Molecular Biology, University of Catania, Viale Messina 829, Catania, - - 2011
To evaluate the efficacy of L-carnitine on alleviating anemia, thrombocytopenia and leukopenia, and minimizing dose reductions in patients with chronic hepatitis C virus (HCV) in treatment with Interferon α (IFN-α) plus ribavirin. Sixty-nine patients with chronic hepatitis C were enrolled in the study and divided into two groups. group A ...
Park Kui Young - - 2011
BACKGROUND: Although hyaluronic acid (HA) fillers are extensively used for the correction of facial wrinkles and folds, there is a limit to patient satisfaction, especially in patients with severe wrinkles. OBJECTIVE: To evaluate the potential for synergistic effects with combined treatment using a nonablative infrared (IR) device and HA filler ...
DE Sisti Antonio - - 2011
Slow-pathway ablation is the treatment of choice for atrioventricular nodal reentrant tachycardia (AVNRT). Cryoablation is effective and safe, but its widespread use seems to be limited by a slightly lower long-term clinical efficacy when compared to radiofrequency (RF) ablation. However, the occurrence of atrioventricular block requiring permanent pacing with RF ...
González-Iglesias Javier - - 2011
OBJECTIVE: The purpose of this prospective case series was to describe the outcomes of a set of rock climbers with lateral epicondylalgia (LE) treated with manual therapy directed at the cervical spine, elbow, and wrist as well as trigger point (TrP) dry needling and kinesio tape. METHODS: Nine consecutive rock ...
Zaupper Louise B - - 2011
Objective.  Despite multiple treatment modalities, protein-losing enteropathy remains a serious complication to Fontan-type operations. Observations suggest inflammation to be involved in the pathogenesis of this condition, and immunomodulating treatment with high-dose intravenous immunoglobulin may modify the condition positively. Patients.  Four patients with protein-losing enteropathy occurring after the total cavopulmonary connection, ...
Bernabeu-Wittel J - - 2011
BACKGROUND AND OBJECTIVES: Recent reports have described the successful use of propranolol to treat severe hemangiomas of infancy. The few case series that have been reported, however, have included only a small number of patients. The aim of this study was to describe the results of oral propranolol treatment for ...
Hegen Harald - - 2011
Backround: Neutralizing antibodies (NAbs) affect the efficacy of interferon-beta (IFNβ) treatment in multiple sclerosis (MS) patients, particularly if NAbs persist. Persistency depends on NAb titers, which differ between IFNβ preparations. Objective: This study evaluated IFNβ preparation-specific NAb cut-off titers during early treatment for prediction of NAb persistency. Methods: Patients who ...
Bloch Sara B SB Department of Ophthalmology, Glostrup Hospital, Glostrup, Denmark University of Copenhagen, Copenhagen, Denmark. - - 2013
To describe predictors of visual outcome in patients treated with intravitreal ranibizumab for choroidal neovascularisation (CNV) in age-related macular degeneration (AMD). Retrospective review of 279 patients with CNV in AMD who fulfilled MARINA/ANCHOR study eligibility criteria and were treated with repeated intravitreal injections of ranibizumab 0.5 mg in routine clinical ...
Gruenwald Ilan - - 2012
Low-intensity shock wave therapy (LI-ESWT) has been reported as an effective treatment in men with mild and moderate erectile dysfunction (ED). The aim of this study is to determine the efficacy of LI-ESWT in severe ED patients who were poor responders to phosphodiesterase type 5 inhibitor (PDE5i) therapy. This was ...
Neff Guy W - - 2011
GOALS:: To evaluate the durability of the response to rifaximin for treatment of hepatic encephalopathy (HE). BACKGROUND:: The nonsystemic antibiotic rifaximin has been approved for maintenance of HE remission, and several studies have indicated the efficacy of rifaximin for acute HE; however, the duration of therapeutic response for >6 months ...
Troutbeck Robyn - - 2011
Background:  To investigate the efficacy of ranibizumab therapy for choroidal neovascular membranes (CNV) secondary to conditions other than macular degeneration. Design:  Prospective case series conducted at the Royal Victorian Eye and Ear Hospital. Participants:  Twelve month follow-up data for 41 patients with CNV recruited from the outpatient clinic from May ...
Tzeis Stylianos - - 2011
Atrial fibrillation (AF) is the most common cardiac arrhythmia and is associated with an increased risk of thromboembolic complications and stroke. Therefore, the implementation of thromboembolic preventive treatment is the cornerstone of quality management in AF patients. During the last 60 years, vitamin K antagonists remain at the forefront of ...
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