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Results 301 - 350 of 3200
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Nair Velu V Dean & Deputy Commandant, Armed Forces Medical College, Pune 411040, - - 2014
The BCR-ABL tyrosine kinase is a well validated therapeutic target in Chronic Myeloid Leukemia (CML). Imatinib mesylate (IM), a tyrosine kinase inhibitor is highly effective in the treatment of chronic phase CML. BCR - ABL transcripts have been well established as a molecular marker to document response to therapy in ...
Al-Shayea Eman I EI Department of Pediatric Dentistry and Orthodontics, Division of Orthodontics, College of Dentistry, King Saud University, Riyadh, Kingdom of Saudi - - 2014
This study aimed to outline orthodontists' perspectives at what stage they would initiate orthodontic treatment and also sought to assess the relationship between orthodontists' views and their genders, types of practice, and experience levels. A questionnaire was sent electronically to 165 practicing orthodontists at different regions in Saudi Arabia. The ...
Hartmann Anke A Department of Dermatology, University Hospital Erlangen, Ulmenweg 18 91054 Erlangen, - - 2014
Targeted UVB intense pulsed light (IPL)-phototherapy has gained interest for repigmentation of vitiligo as it allows selective treatment, sparing the surrounding skin. However, optimal treatment frequency and duration are not known. We compared the efficacy and safety of two treatment protocols, weekly and every two weeks, for a maximum of ...
Jain Rohit R Senior Lecturer, Department of Periodontics, Desh Bhagat Dental College and Hospital , KK Road, Muktsar, Punjab, India - - 2014
Background: Since the advent of nanotechnology, various materials have been introduced for the treatment of the bone defects which have shown promising results. Aim: The purpose of this study was to compare the effect of nano-sized Hydroxyapatite (NHA) and β-Tricalcium Phosphate (β-TCP) in the treatment of human periodontal defects. Materials ...
Poole Brolin B BB PGY1 Pharmacy Resident, Department of Pharmacy, University of Tennessee Medical Center , Knoxville, - - 2014
The use of gemcitabine may lead to numerous adverse effects ranging from mild to very severe, such as interstitial pneumonitis. The diagnosis of this complication is based on multiple laboratory findings, radiographic evidence, and high clinical suspicion. Presented is a case report of a patient who met these criteria and ...
Zhu Hui H Department of Dermatology, Second Hospital of Tianjin Medical University, Tianjin, - - 2014
Pseudoepitheliomatous, keratotic, and micaceous balanitis (PKMB) is an extremely rare condition occurring over the glans in older men who undergo circumcision late in life. Its exact etiology is unknown. We report a patient with PKMB that involved the meatus and led to urinary obstruction. A 57-year-old, circumcised man presented with ...
Muram David D Lilly USA, LLC, Indianapolis, IN, - - 2014
Patterns of care following topical testosterone agent (TTA) initiation are poorly understood. This study aimed to characterize care following TTA initiation and compare results between patients with and without a serum testosterone (T) assay within 30 days before and including TTA initiation. Adult men (N = 4,146) initiating TTAs from ...
Hokari Masaaki M Department of Neurosurgery, Kushiro Rousai Hospital, Kushiro-shi, Hokkaido, Japan. Electronic address: - - 2014
Since the introduction of carotid stenting (CAS), a combined treatment for bilateral lesions using carotid endarterectomy (CEA) and CAS has been developed. However, there has been only 1 report about CEA then CAS. Herein we describe 2 patients with bilateral severe carotid stenosis who were treated by CEA for the ...
Omrani Ali S AS Division of Infectious Diseases, Prince Sultan Military Medical City, Riyadh, Saudi - - 2014
Middle East respiratory syndrome coronavirus (MERS-CoV) infection is associated with high mortality and has no approved antiviral therapy. We aimed to compare ribavirin and interferon alfa-2a treatment for patients with severe MERS-CoV infection with a supportive therapy only. In this retrospective cohort study, we included adults (aged ≥16 years) with ...
Galanis Taki T Department of Surgery, Jefferson Vascular Center, Jefferson Medical College, Thomas Jefferson University Hospitals, Philadelphia, - - 2014
Several novel oral anticoagulants have been studied for the prevention and treatment of venous thromboembolism (VTE) in different patient populations. Clinicians will increasingly encounter scenarios in which they must choose among these and conventional anticoagulants for the treatment of this potentially fatal condition. To review the results of Phase III ...
Giladi Nir N Department of Neurology, Tel-Aviv University, Tel-Aviv, Israel; Sago School of Neuroscience, Tel-Aviv University, Tel-Aviv, Israel. Electronic address: - - 2014
In two 6-month, double-blind, placebo-controlled studies, rotigotine transdermal system was well-tolerated and efficacious monotherapy in early-stage PD. This post hoc analysis of the long-term open-label extensions (NCT00594165; NCT00599196) of these studies assessed incidence and severity of dyskinesia in participants treated with rotigotine, with or without concomitant levodopa, for up to ...
Geynisman Daniel M DM Department of Medical Oncology, Fox Chase Cancer Center, Temple Health, Philadelphia, - - 2014
To evaluate the evolution of treatment patterns and associated costs for metastatic renal cell carcinoma (mRCC) in the United States. The LifeLink Health Plan Claims Database was used to create a cohort of mRCC patients with at least 12 months of continuous enrollment from 2004 to 2011. We summarized treatment ...
Hamzeh Nabeel N Division of Environmental and Occupational Health Sciences, Department of Medicine, National Jewish Health, Denver, CO, USA; Division of Pulmonary and Critical Care Sciences, Department of Medicine, University of Colorado, Aurora, CO, USA. Electronic address: - - 2014
Immunosuppressive (IS) therapy is indicated to treat progressive sarcoidosis, but randomized controlled trials to guide physicians in the use of steroid sparing agents are lacking. The aim of this retrospective study was to examine the role of mycophenolate mofetil (MMF) as an alternative therapy in the treatment of sarcoidosis. A ...
DeWitt Elizabeth S ES Department of Cardiology; Boston Children's Hospital & Department of Pediatrics, Harvard Medical School, Boston, - - 2014
-Implantable cardioverter-defibrillators (ICDs) used to prevent sudden cardiac arrest in children provide appropriate therapy in 25% of patients, but also result in a significant incidence of inappropriate shocks and other device complications. ICDs placed for secondary prevention have higher rates of appropriate therapy than those placed for primary prevention. Pediatric ...
Bonnet Delphine D Delphine Bonnet, Matthieu Guivarch, Anaïs Palacin, Laurent Alric, Internal Medicine-Digestive Department, Purpan University Hospital, 31059 Toulouse cedex 9, - - 2014
To assess, in a routine practice setting, the sustained virologic response (SVR) to telaprevir (TPV) or boceprevir (BOC) in hepatitis C virus (HCV) null-responders or relapsers with severe liver fibrosis. One hundred twenty-five patients were treated prospectively for 48 wk with TPV or BOC + pegylated-interferon (peg-INF) α2a + ribavirin ...
Glatz Andrew C AC Divisions of Cardiology, Children's Hospital of Philadelphia; Department of Pediatrics, Perelman School of Medicine at the University of Pennsylvania; Center for Clinical Epidemiology and Biostatistics, Perelman School of Medicine at the University of - - 2014
Objectives: To describe the results of a clinical practice pathway (CPP) for the management of post-catheterization pulse loss in a children's hospital. Background: Standardized approaches to the diagnosis and management of post-catheterization arterial thrombus are lacking. As a result, substantial practice variation exists. Methods: Data collected prospectively for QI purposes ...
Ho M M Department of Ophthalmology & Visual Sciences, Chinese University of Hong Kong, Prince of Wales Hospital, Hong Kong SAR, Hong - - 2014
AimTo report the visual outcome of polypoidal choroidal vasculopathy receiving combined treatment with photodynamic therapy using Visudyne and intravitreal ranibizumab injections, and to analyze the predictive factors of visual outcome at 1 year post treatment.MethodsSeventy-four consecutive patients with newly diagnosed polypoidal choroidal vasculopathy were treated with photodynamic therapy using Visudyne ...
Korkmaz Serdal S Division of Hematology, Kayseri Education and Research Hospital, Kayseri, - - 2014
We aimed to investigate whether older age leads to limitations in the starting dose of imatinib in daily treatment of chronic myeloid leukemia, and to determine the compliance of elderly patients with tyrosine kinase inhibitors (TKI) therapy. Data including the clinical characteristics, therapeutic outcomes and compliance with TKI therapy of ...
Collins Peter W PW Arthur Bloom Haemophilia Centre, Institute of Infection and Immunity, School of Medicine, Cardiff University, Cardiff, United Kingdom; - - 2014
This multinational, randomized, single-blind trial (NCT01333111 [www.clinicaltrials.gov]) investigated safety and efficacy of nonacog beta pegol, a recombinant glycoPEGylated factor IX (FIX) with extended half-life, in 74 previously treated hemophilia B patients (FIX activity ≤2 IU/dL). Patients received prophylaxis for 52 weeks, randomized to 10 IU/kg or 40 IU/kg once weekly, ...
Melo Mônica de Oliveira MD Exercise Research Laboratory, Federal University of Rio Grande do Sul, Porto Alegre, Brazil Núcleo de Pesquisa em Ciências e Arte do Movimento Humano, University of Caxias do Sul, Caxias do Sul, Brazil - - 2014
To determine the effects of low-level laser therapy in combination with neuromuscular electrical stimulation on the muscle architecture and functional capacity of elderly patients with knee osteoarthritis. A randomized, evaluator-blinded clinical trial with sequential allocation of patients to three different treatment groups. Exercise Research Laboratory. A total of 45 elderly ...
Pavone Vito V Department of Orthopedics, Azienda Ospedaliero-Universitaria Policlinico Vittorio Emanuele, Catania, - - 2014
Developmental dysplasia of the hip is an anomaly of the hip joint. In patients with early diagnosis, within 3 to 6 months of life, the treatment is essentially conservative and involves the use of dynamic harness. The indication for the use of the Tubingen hip flexion splint is a dysplastic ...
Hägi Tobias T - - 2014
Objectives: To characterize the physical characteristics of a new low abrasive erythritol powder (EPAP) and to evaluate its influence on the clinical and microbiologic parameters over a period of 6 months in patients undergoing supportive periodontal therapy (SPT). Method and Materials: Prior to the clinical application, the particle size and ...
Simon J-C JC Department of Dermatology, Venereology and Allergology, University of Leipzig Medical Center, Leipzig, - - 2014
Actinic keratoses (AKs) are clinically significant and require therapy. Efficacy of low-dose (0.5%) 5-fluorouracil with 10% salicylic acid (5-FU/SA) has been shown in randomized comparative trials of hyperkeratotic lesions of various grades. To evaluate the efficacy, tolerability and safety of low-dose 5-FU/SA topical solution vs. cryosurgery in patients with moderate/severe ...
Lee Seung Won SW Department of Otolaryngology-Head and Neck Surgery, Soonchunhyang University School of Medicine, Bucheon, - - 2014
Arytenoid dislocation is a rare condition characterized by vocal fold immobility and is easily mistaken as recurrent laryngeal nerve paralysis. To describe the presenting features, multimodal diagnostic evaluation, and surgical outcomes following closed reduction (CR) of arytenoid dislocation. Prospective case series at a single academic medical center. Evaluation and treatment ...
Comi G G University Vita-Salute San Raffaele, San Raffaele Scientific Institute, Italy - - 2014
In post hoc analyses of an open-label, phase 3b study (FIRST), relapse rates during 4 months of fingolimod therapy were compared in patients with and without previous natalizumab exposure. Reductions in the proportion of patients experiencing relapses and annualized relapse rates (ARRs) from years 1 and 1-2 pre-study were evident ...
Pfister Christian C Urology Department, Charles Nicolle University Hospital, Rouen, France; Clinical Investigation Center, Inserm 6204, Onco-Urology Group, Rouen, - - 2014
To assess bacillus Calmette-Guérin maintenance treatment schedule for non-muscle invasive bladder cancer at 2 years, using one-third of the full dose and fewer instillations every 3 months or 6 months. This was a prospective, randomized, multicenter study. All patients had an intermediate- or high-risk non-muscle invasive bladder cancer. They received ...
Lapusan Simona S Saint Antoine Hospital, Pierre and Marie Curie University, Paris, - - 2014
Patients with chronic myeloid leukemia in chronic phase who achieve early molecular response (EMR; generally defined as BCR-ABL ≤ 10% on the International Scale at 3 or 6 months) have improved outcomes. However, there is no consensus on whether EMR failure at 3 months requires a change in therapy, and the ...
Cocco Eleonora E Multiple Sclerosis Center, ASL 8, Cagliari/ University of Cagliari, - - 2014
A critical aspect of multiple sclerosis (MS) treatments is understanding the effect of disease-modifying drugs (DMDs) on the long-term risk of disability and whether the effect is related to disability at start of treatment. We performed an observational study on 3060 MS patients. The effect of therapy on progression to ...
Jones Christopher M CM College of Medical & Dental Sciences, University of Birmingham, United - - 2014
Patients who develop significant dysphagia secondary to a potentially curable oesophageal cancer pose a significant clinical problem. Their nutritional needs can be met either by dietary supplementation, insertion of an oesophageal stent or through nasogastric or surgical feeding tube placement. We sought to determine whether, in patients about to start ...
Connolly Stuart J SJ McMaster University, Hamilton, ON, Canada - - 2014
To the Editor: Boehringer Ingelheim recently conducted a targeted review of the 1387 deaths that occurred during the Randomized Evaluation of Long-Term Anticoagulation Therapy (RE-LY) trial,(1) which evaluated the effects of two doses of dabigatran, as compared with warfarin, on rates of stroke or systemic embolism and major bleeding. Also ...
Zhang Feng F Department of Surgery, The First Hospital of Hebei Medical University, Shijiazhuang, 050030, Hebei, - - 2014
The purpose of this study was to conduct a systematic review with meta-analysis quantitatively assesses the outcomes of interventional treatment for Budd-Chiari syndrome (BCS). We evaluated the published studies on interventional treatment for BCS and reviewed reference lists from retrieved articles. Meta-analysis was applied to calculate the combined rates and ...
Dewilde Willem J M WJ Department of Cardiology, Amphia Hospital, Breda, the Netherlands. Electronic address: - - 2014
Chronic oral anticoagulant therapy is recommended (class I) in patients with mechanical heart valves and in patients with atrial fibrillation with a CHA2DS2-VASc (Congestive heart failure, Hypertension, Age ≥75 years, Diabetes mellitus, prior Stroke or transient ischemic attack or thromboembolism, Vascular disease, Age 65 to 74 years, Sex category) score ≥1. When ...
Swidsinski Alexander A Laboratory for Molecular Genetics, Polymicrobial Infections and Bacterial Biofilms and Department of Medicine, Gastroenterology, Charité Hospital, Campus Mitte, Universitätsmedizin Berlin, 10117, Berlin, Germany, - - 2014
Bacterial vaginosis is a recalcitrant polymicrobial biofilm infection that often resists standard antibiotic treatment. We therefore considered repeated treatment with octenidine, a local antiseptic that has previously been shown to be highly effective in several biofilm-associated infections. Twenty-four patients with recurrent BV were treated with a 7-day course of octenidine ...
Wang Chun C Department of Neurology, People's Hospital of Deyang City, Deyang, - - 2014
To evaluate the effects of treatments with clopidogrel plus aspirin (dual therapy) on early neurological deterioration (END) and outcomes at 6 months in patients with acute large artery atherosclerosis (LAA) stroke. A total of 574 patients with LAA stroke were randomly assigned to receive either dual therapy or aspirin alone ...
Hanselman Andrew E AE Department of Orthopaedics, West Virginia University School of Medicine, Morgantown, WV, USA - - 2014
Treatment options for plantar fasciitis have resulted in varied patient outcomes. The aim of this study was to compare a novel treatment, cryopreserved human amniotic membrane (c-hAM), to a traditional treatment, corticosteroid. Our hypothesis was that c-hAM would be safe and comparable to corticosteroids for plantar fasciitis in regard to ...
Rahimi Robert S RS Department of Internal Medicine, University of Texas Southwestern Medical Center, Dallas2Parkland Memorial Hospital, Parkland Health and Hospital System, Dallas, Texas3Now with Annette C. and Harold C. Simmons Transplant Institute, Baylor University - - 2014
Hepatic encephalopathy (HE) is a common cause of hospitalization in patients with cirrhosis. Pharmacologic treatment for acute (overt) HE has remained the same for decades. To compare polyethylene glycol 3350-electrolyte solution (PEG) and lactulose treatments in patients with cirrhosis admitted to the hospital for HE. We hypothesized that rapid catharsis ...
Shinagawa Katsuji K Katsuji Shinagawa, Okayama University Hospital, Okayama; Masamitsu Yanada and Nobuhiko Emi, Fujita Health University School of Medicine, Toyoake; Toru Sakura, Saiseikai Maebashi Hospital, Maebashi; Yasunori Ueda, Kurashiki Central Hospital, Kurashiki; Masashi Sawa, Anjo Kosei Hospital, Anjo; Junichi Miyatake, Kinki University Faculty of Medicine, Osakasayama; Nobuaki Dobashi, Jikei University School of Medicine; Yoshihiro Hatta, Nihon University School of Medicine; Yukio Kobayashi, National Cancer Center Hospital, Tokyo; Minoru Kojima, Tokai University School of Medicine, Isehara; Shigehisa Tamaki, Ise Red Cross Hospital, Ise; Hiroshi Gomyo, Hyogo Cancer Center, Akashi; Etsuko Yamazaki, Graduate School of Medicine and Faculty of Medicine, Yokohama City University, Yokohama; Katsumichi Fujimaki, Fujisawa City Hospital, Fujisawa; Norio Asou, International Medical Center, Saitama Medical University, Hidaka; Keitaro Matsuo, Kyushu University Faculty of Medical Sciences, Fukuoka; Shigeki Ohtake, Kanazawa University Graduate School of Medical Sciences, Kanazawa; Yasushi Miyazaki, Atomic Bomb Disease Institute, Nagasaki University, Nagasaki; Kazunori Ohnishi, Hamamatsu University School of Medicine, Hamamatsu; and Tomoki Naoe, Nagoya University Graduate School of Medicine and National Hospital Organization Nagoya Medical Center, Nagoya, - - 2014
The introduction of all-trans-retinoic acid (ATRA) has significantly improved outcomes for acute promyelocytic leukemia (APL), although a subset of patients still suffer relapse. The purpose of this study was to evaluate the role of maintenance therapy with the synthetic retinoid tamibarotene in APL. Patients with newly diagnosed APL in molecular ...
Nobile-Orazio Eduardo E 2nd Neurology, Department of Medical Biotechnology and Translational Medicine, Milan University, Humanitas Clinical and Research Center, Milan, - - 2014
We reported that 6-month therapy with intravenous immunoglobulin (IVIg) was more frequently effective or tolerated than intravenous methylprednisolone (IVMP) in patients with chronic inflammatory demyelinating polyradiculoneuropathy (CIDP). We now retrospectively compared the proportion of patients who eventually worsened after discontinuing therapy and the median time to clinical worsening. By March ...
Arnal-García Carmen C Neurology Service, Hospital Universitario Virgen de las Nieves, Avenida Juan Pablo II, S/N, 18013 Granada, Spain. Electronic address: - - 2014
Glatiramer acetate currently represents one of the main treatments for relapsing-remitting multiple sclerosis (RRMS). However, the information available about its long-term effect in clinical practice is still limited. Thus, this multicenter retrospective cohort study aimed to assess the long-term effectiveness of glatiramer acetate in this setting. The study population included ...
Chung Seong Min SM Department of Internal Medicine, Seoul National University College of Medicine, Seoul National University Bundang Hospital, Seongnam-si, Gyeonggi-do, - - 2014
Objectives: This study investigated the antiviral efficacy of adefovir (ADV) rescue therapy and the feasibility of lamivudine (LAM) discontinuation in LAM-resistant chronic hepatitis B (CH-B) patients who had attained a virological response (VR) with LAM + ADV combination therapy. Methods: The VR and virological breakthrough (VBT) were analyzed in 106 ...
Huang Kun-Ling KL Department of Otolaryngology-Head and Neck surgery, Chang Gung Memorial Hospital, Chiayi, - - 2014
Dysphagia after stroke is associated with mortality and increased pulmonary complications. Swallowing therapies may decrease pulmonary complications and improve patients' quality of life after stroke. This study used clinical swallowing assessments and videofluoroscopy (VFS) to assess the functional recovery of acute stroke patients with dysphagia after different swallowing therapies. We ...
Chopinaud Marianne M Department of Dermatology, Caen University Hospital, Caen, - - 2014
Background: A variety of treatment modalities have been proposed to treat keloid scars, but outcomes are often disappointing. Intralesional cryosurgery may significantly reduce these scars. Objective: To evaluate the clinical safety and efficacy of intralesional cryosurgery to treat keloid scars. Feedback from patients on pain, pruritus and aesthetic discomfort was ...
Gisbert Javier P JP Gastroenterology Department, Hospital Universitario de La Princesa, Instituto de Investigación Sanitaria Princesa (IP), Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas (CIBEREHD), Playa de Mojácar 29. Urb. Bonanza, 28669, Boadilla del Monte, Madrid, Spain, - - 2014
Helicobacter pylori eradication is a challenge in penicillin allergy. To assess the efficacy and safety of first-line and rescue treatments in patients allergic to penicillin. Prospective multicenter study. Patients allergic to penicillin were given a first-line treatment comprising (a) 7-day omeprazole-clarithromycin-metronidazole and (b) 10-day omeprazole-bismuth-tetracycline-metronidazole. Rescue treatments were as follows: ...
Bassi A A Department of Surgery and Translational Medicine, section of DermatologyUniversity of Florence Medical School, Florence, Italy - - - 2014
Rhinophyma is a benign, disfiguring disorder, commonly reffered to as the end stage of severe rosacea and characterized by a progressive thickening and hypertrophy of the nasal skin and soft tissues.. To evaluate the efficacy of CO2 laser compared to other laser techniques and surgical methods in the treatment of ...
Tang Shenjie S Tuberculosis Multidisciplinary Center for Diagnosis and Treatment, Beijing Chest Hospital, Capital Medical University, Beijing Tuberculosis and Thoracic Tumour Research Institute, Beijing, China Tuberculosis Center for Diagnosis and Treatment, Shanghai Pulmonary Hospital, Tongji University School of Medicine, Shanghai, China Authors contributed - - 2014
Linezolid may be effective in treating multidrug-resistant tuberculosis and extensively drug-resistant tuberculosis. We conducted a prospective, multicentre, randomised study to further evaluate the efficacy, safety and tolerability of linezolid in patients with extensively drug-resistant tuberculosis in China. 65 patients who had culture-positive sputum for extensively drug-resistant tuberculosis were randomly assigned ...
Kwon Yoon Hyung YH Department of Ophthalmology, Dong-A University College of Medicine, Busan, Korea. ; Retina Center, Nune Eye Hospital, Seoul, - - 2014
This pilot study aimed to evaluate the efficacy and safety of subthreshold micropulse yellow (577-nm) laser photocoagulation (SMYLP) in the treatment of diabetic macular edema (DME). We reviewed 14 eyes of 12 patients with DME who underwent SMYLP with a 15% duty cycle at an energy level immediately below that ...
Macedo P M PM Dermatology Department, Rio de Janeiro State University (Universidade do Estado do Rio de Janeiro), Rio de Janeiro, - - 2014
The first therapeutic choice for the treatment of cutaneous sporotrichosis is oral itraconazole; however, the increase in cases of zoonotic transmission outbreak necessitates a search for effective and safe treatment alternatives. To evaluate a new potassium iodide (KI) posology as an alternative for the treatment of limited cutaneous forms of ...
Lim Henry W HW Multicultural Dermatology Center, Department of Dermatology, Henry Ford Hospital, Detroit, - - 2014
Narrowband UV-B (NB-UV-B) phototherapy is used extensively to treat vitiligo. Afamelanotide, an analogue of α-melanocyte-stimulating hormone, is known to induce tanning of the skin. To evaluate the efficacy and safety of combination therapy for generalized vitiligo consisting of afamelanotide implant and NB-UV-B phototherapy. This study was performed in 2 academic ...
Treister Nathaniel N Division of Oral Medicine and Dentistry, Dana-Farber/Brigham and Women's Cancer Center, Boston, - - 2014
Oral chronic graft-versus-host disease (cGVHD) is a debilitating complication following allogeneic hematopoietic cell transplantation (HCT). The objective of this study was to evaluate the safety and efficacy of intraoral narrow-band UVB (NB-UVB) phototherapy in the management of oral cGVHD. Patients with oral cGVHD were treated using a custom NB-UVB unit ...
Sauer N N Department for Endocrinology and Diabetology, University Hospital Hamburg Eppendorf (UKE), Hamburg, - - 2014
The aim of the work was to investigate whether continuation of treatment, side effects, and effect on weight loss of GLP-1 agonists in obese patients without diabetes are equally promising in daily clinical-practice-settings compared to controlled clinical trials. Obese patients without diabetes of our interdisciplinary obesity centre were treated off-label ...
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