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Results 301 - 350 of 3073
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Sood Ajit A Dayanand Medical College and Hospital, Punjab, - - 2014
Introduction. Standard treatment for patients with chronic hepatitis C genotype 1 (CHC G-1) infection includes pegylated interferon plus ribavirin (PEG-RBV) for 48 weeks. Shorter treatment regimen would be more acceptable due to lower cost and fewer side-effects. We aimed to compare the efficacy of 36 week PEG-RBV therapy with standard ...
Faisal Nabiha N Toronto General Hospital, University of Toronto. Ontario, - - 2014
Introduction. Hepatitis C (HCV) continues to be the leading indication for liver transplantation (LT). Sustained virological response (SVR) rates to pegylated interferon (PEG-IFN) and ribavirin (RBV) therapy for recurrent HCV in Genotype 1 (G1) LT recipients have been disappointing (30-40%). Experience with triple therapy using protease inhibitors (PI) boceprevir (BOC), ...
Vela M F MF Division of Gastroenterology and Hepatology, Mayo Clinic Arizona, Scottsdale, AZ, - - 2014
Treatment options for achalasia include oral pharmacologic therapy, endoscopic injection of botulinum toxin, pneumatic dilation, and myotomy (conventionally by laparoscopy, but more recently by an endoscopic approach). Oral pharmacologic agents have fallen out of use because of insufficient efficacy and frequent side effects. Endoscopic injection of botulinum toxin is safe ...
Leybovich Martin - - 2014
This study compared two treatments for mild noncarious cervical lesions (NCCLs): a subepithelial connective tissue graft (CTG) versus a Class V composite resin restoration (CRR). Twenty-six sites with NCCLs were randomly assigned to be treated by CTG or CRR. Periodontal health parameters and dentinal hypersensitivity (DH) were recorded at baseline ...
Levy Jerrold H JH Duke University School of Medicine, Divisions of Cardiothoracic Anesthesiology and Critical Care, Duke University Hospital, 2301 Erwin Road, Durham, NC 27710, USA. Electronic address: - - 2014
Bleeding is a significant complication of anticoagulant therapy. With the emergence of new oral anticoagulants (NOACs; ie, direct factor IIa or Xa inhibitors), this risk is further compounded by the lack of validated reversal strategies for these agents. Emerging postmarketing evidence suggests that the bleeding risks are in line with ...
Zhao Dahang D Department of Pediatric Orthopaedics, Xin-Hua Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, - - 2014
Ponseti clubfoot treatment has become more popular during the last decade because of its high initial correction rate. But the most common problem affecting the long-term successful outcome is relapse of the deformity. Non-compliance with Ponseti brace protocol is a major problem associated with relapse. Although more comfortable braces have ...
Gray M M Division of Neonatology, Department of Pediatrics, The Children's Hospital of Philadelphia, Philadelphia, PA, - - 2014
Historically, congenital pulmonary lymphangiectasia (CPL) has had poor treatment outcomes despite aggressive therapy. There are recent reports of ethiodized oil (Lipiodol) lymphangiography successfully treating lymphatic leakage in adults. In this report, we describe two infants with CPL complicated by chylothoraces successfully treated by instillation of ethiodized oil into the lymphatic ...
Wallace Carol A CA From the Seattle Children's Hospital and Research Institute, Seattle, Washington; University of Utah, Pediatrics, Salt Lake City, Utah; Cleveland Clinic, Cleveland, Ohio; Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio; University of California at San Francisco, San Francisco, California; Duke University Medical Center, Pediatrics, Durham, North Carolina; Ohio State University and Nationwide Children's Hospital, Pediatrics, Columbus, Ohio; University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma; Steven and Alexandra Cohen Children's Medical Center of New York, New York; Stanford University School of Medicine, Palo Alto, California; Texas Scottish Rite Hospital, Dallas, Texas; Joseph M. Sanzari Children's Hospital at Hackensack University Medical Center, Hackensack, New Jersey, USA. Supported by grants from US National Institute of Arthritis and Musculoskeletal and Skin Diseases: 5R01AR049762-04; AMGEN; and the Howe Endowment for Juvenile Rheumatoid Arthritis Research. C.A. Wallace, MD; S. Ringold, MD, MS, Seattle Children's Hospital and Research Institute; J. Bohnsack, MD, University of Utah; S.J. Spalding, MD, Cleveland Clinic; H.I. Brunner, MD, MSc, Cincinnati Children's Hospital Medical Center; D. Milojevic, MD, University of California at San Francisco; L.E. Schanberg, MD, Duke University Medical Center; G.C. Higgins, PhD, MD, Ohio State University and Nationwide Children's Hospital; K.M. O'Neil, MD, Oklahoma University Health Science Center, now at Riley Hospital for Children, Indianapolis, Indiana; B.S. Gottlieb, MD, MS, Steven and Alexandra Cohen Children's Medical Center of New York; J. Hsu, MD, MS, Stanford University School of Medicine; M.G. Punaro, MD, Texas Scottish Rite Hospital; Y. Kimura, MD, Joseph M. Sanzari Children's Hospital at Hackensack University Medical Center; A. Hendrickson, MPH, Seattle Children's Hospital and Research Institute. Address correspondence to Dr. C.A. Wallace, Professor of Pediatrics, Division of Rheumatology, University of Washington and Seattle Children's Hospital, 4800 Sand Point Way NE, R-5420, Seattle, Washington 98105, USA. E-mail: cwallace@u.washington.edu. Accepted for publication June 25, - - 2014
To follow children with juvenile idiopathic arthritis (JIA) who had completed at least 6 months of the TRial of Early Aggressive Therapy (TREAT) clinical study for an additional 2 years, describing safety of early aggressive treatment, disease activity, function, and duration of clinical inactive disease (CID) during followup. Children were ...
Pauls Rachel N RN From the *Division of Urogynecology and Reconstructive Pelvic Surgery, TriHealth Good Samaritan Hospital, †Center for Pelvic Floor and Core Rehabilitation, and ‡Hatton Institute for Research and Education, TriHealth, Cincinnati, - - 2014
Pelvic floor physical therapy (PFPT) is often used as a treatment of pelvic floor disorders and may improve function after pelvic reconstructive surgery. However, the long-term impact of this modality is not understood. This randomized controlled trial compared PFPT to the standard care in women undergoing vaginal reconstruction. The intervention ...
Li Hongyang H Department of Ophthalmology, Chinese People's Liberation Army General Hospital, Beijing 100853, - - 2014
Optic neuritis (ON) is often the first symptom of multiple sclerosis (MS) and neuromyelitis optica (NMO) while there has been very little research reported on ON combined with Sjögren's syndrome (SS). The aim of this study is to provide different treatments and services for and NMO patients combined with SS. ...
Galvan Garcia Hector Ricardo HR Dermatology Hospital, Dermatosurgery, Guadalajara, Jalisco, - - 2014
Laser Treatment of onychomycosis is a quick and easy method without complications. Laser therapy is efficient for the Treatment of onychomycosis. One hundred and twenty patients with a KOH (+) confirmed clinical diagnosis of onychomycosis were included in this study, all of the patients were treated in a single sesión ...
Yoshizawa Naohiko N Department of Gastroenterology, Aichi Cancer Center - - 2014
A patient in her 60s was referred to our hospital with pancreatic enlargement. Laboratory data and endoscopic ultrasound-guided fine needle aspiration (EUS-FNA) revealed a nonfunctioning pancreatic neuroendocrine tumor (WHO classification 2010 G2). Resection was contraindicated because of portal vein invasion and extensive collateral vascularization. Everolimus (10 mg/day) was started after ...
Güngör Sule S Department of Dermatology, Okmeydanı Training and Research Hospital, Istanbul, - - 2014
Striae distensae or stretch marks are atrophic linear dermal scars with epidermal atrophy. There are many therapeutic options for management, but no consistently effective modality is available yet. We compared the efficacy of 1064 nm long pulse (LP) Nd: YAG laser and 2940 nm variable square pulse (VSP) erbium: YAG ...
Esmaili Nafiseh N Autoimmune Bullous Diseases Research Center, Tehran University of Medical Sciences, Tehran, Iran, Department of Dermatology, Tehran University of Medical Sciences, Tehran, Iran Department of Pathology, Tehran University of Medical Sciences, Tehran, Iran. - - 2014
Pemphigus is an autoimmune blistering mucocutaneous disorder. Common treatments include corticosteroids and immunosuppressive drugs. This study aimed to assess the therapeutic effects of oral prednisolone along with the common adjuvant therapy in pemphigus vulgaris.   Eighty-seven patients with pemphigus vulgaris from the first stage of a previously randomized clinical trial ...
Xiong Ji J Department of Gastroenterology, Institute of Surgery Research, Daping Hospital (JX, SL, PZ, QL, YW, YY, TW, LL, DC); Department of Epidemiology, College of Preventive Medicine (XM); and Center for Clinical Epidemiology and Evidence-Based Medicine, Third Military Medical University, Chongqing, People's Republic of China - - 2014
Proton pump inhibitor (PPI) was the main prescription for gastric ulcer after endoscopic submucosal dissection (ESD). Some randomized controlled trials showed that a combination of rebamipide and PPI appears to be more efficient than PPI alone for the treatment of ESD-induced gastric ulcer. However, the sample sizes in these trials ...
Serra Maíra Chiarelli MC Divisione Melanoma, Istituto Europeo di Oncologia, Milano, - - 2014
A 25-year-old Caucasian female with multiple genital warts involving the vulvar area was treated with imiquimod 5% cream. During follow-up the patient developed areas of hypopigmentation at the site of application of imiquimod cream and areas of hypomelanosis around multiple preexisting nevi of the trunk. At 18 months follow-up genital ...
Hevia Oscar - - 2014
Utilizing a soft-tissue filler that is more fluid and less resistant to deformation may be advantageous for correction of infraorbital hollows.<BR /> The objective of this study was to determine the safety and efficacy of the latest hyaluronic acid filler, created with a cohesive polydensified matrix, with a low elasticity ...
Sundar Shyam S Department of Medicine, Institute of Medical Sciences, Banaras Hindu University, Varanasi, - - 2014
India is home to 60% of the total global visceral leishmaniasis (VL) population. Use of long-term oral (e.g. miltefosine) and parenteral drugs, considered the mainstay for treatment of VL, is now faced with increased resistance, decreased efficacy, low compliance and safety issues. The authors evaluated the efficacy and safety of ...
Farber Alik A Division of Vascular and Endovascular Surgery, Boston Medical Center, Boston, MA. Electronic address: - - 2014
Critical limb ischemia (CLI) is the most severe form of peripheral arterial disease and is associated with a significant risk of limb loss. It is currently treated with limb revascularization by a variety of specialists. Although both open vascular bypass and endovascular therapy are offered to patients with infrainguinal peripheral ...
Barth Jodi Maron JM National Rehabilitation Hospital, Regional Rehab at Montrose, Rockville, MD, - - 2014
We conducted a retrospective chart review to determine the effectiveness of treating idiopathic facial palsy with mirror book therapy in conjunction with facial physical rehabilitation. We compared outcomes in 15 patients who underwent mirror book therapy in addition to standard therapy with those of 10 patients who underwent standard rehabilitation ...
- - 2014
Background: The main clinical manifestations of autoimmune thyroid diseases are Graves' disease (GD) and Hashimoto's thyroiditis (HT). Graves' disease is the cause of most cases of hyperthyroidism in childhood. Indications for radical therapy (surgery or 131I treatment) in children are still a matter of discussion, as sustained (sometimes very long) ...
Salome G M GM Sapucaí Valley University (UNIVÁS), Pouso Alegre, MG, - - 2014
• To assess self-esteem in patients with venous leg ulcers treated with Unna's boot. • A descriptive, analytic, clinical study was conducted from June 2010 to May 2011 in an outpatient wound care clinic in São Paulo, Brazil. Patients of both sexes, aged ≥18 years, who had had a venous ...
Mummolo Stefano - - 2014
This study evaluated the efficacy of a xanthan-based chlorhexidine gel (Xan-CHX) used as antiseptic in periodontal pockets after scaling and root planing in patients with generalized mild-severe chronic periodontitis. 30 systemically healthy patients, 15 males and 15 females (mean age 54,1 ± 6,9 years), diagnosed for chronic periodontitis were enrolled ...
Hong Wandong W Department of Gastroenterology and Hepatology, First Affiliated Hospital of Wenzhou Medical University, Wenzhou, Zhejiang, - - 2014
There is no consensus regarding the most appropriate methods (i.e., the side-by-side versus the stent-in-stent technique) for placing bilateral stents for malignant hilar biliary obstructions. We aimed to perform a quantitative review of the published data regarding the clinical efficacy of the side-by-side and stent-in-stent bilateral drainage techniques for hilar ...
Teivelis Marcelo Passos MP Hospital Israelita Albert Einstein, Vascular Surgery, São Paulo, SP, - - 2014
Primary hyperhidrosis usually affects the hands, armpits, feet and cranio-facial region. Sweating in other areas is common in secondary hyperhidrosis (after surgery or in specific clinical conditions). Oxybutynin has provided good results and is an alternative for treating hyperhidrosis at common sites. Our aim was to evaluate the efficacy of ...
Ze EunYoung E Department of Internal Medicine, Chung-Ang University College of Mediciner, Seoul, - - 2014
Adefovir (ADV) and lamivudine (LAM) combination therapy (ADV+LAM) has been a useful option for patients with LAM-resistant (LAM-r) chronic hepatitis B (CHB). However, the long-term outcomes of LAM+ADV and 1-mg entecavir (ETV) rescue therapies have still been limited. The aim of this study was to determine the long-term outcomes of ...
Ahn Sung Soo SS Department of Internal Medicine, Yonsei University College of Medicine, Seoul, - - 2014
This study assessed the antiviral efficacy and safety of tenofovir disoproxil fumarate (TDF) for up to 12 months in Korean treatment-naïve chronic hepatitis B (CHB) patients. A total of 411 treatment-naïve CHB patients who had been treated with TDF for at least 3 months (median 5.6) were consecutively enrolled. Clinical, ...
Kim Jeong Han JH Department of Internal Medicine, Konkuk University School of Medicine, Seoul, - - 2014
Quantitation of hepatitis B surface antigen (HBsAg) is an increasingly popular method to determine the treatment response in chronic hepatitis B (CHB) patients. The clinical value of HBsAg level measurement during rescue therapy for lamivudine (LMV)-resistant CHB patients have not been evaluated to date. Therefore, this study investigated the correlation ...
De Bk B Department of Medicine, Medical College, Kolkata, West Bengal, - - 2014
Prednisolone and pentoxifylline (PTX) have been shown to be individually useful in severe alcoholic hepatitis with Maddrey discriminant function (MDF) score ≥32. Previous report suggests that PTX is probably superior to prednisolone alone. However the efficacy of PTX and prednisolone combination over PTX alone in the management of acute alcoholic ...
Bomprezzi Roberto R MaineGeneral Neurology, MaineGeneral Medical Center, 15 Enterprise Dr, Augusta, ME 04330, - - 2014
The enthusiasm for natalizumab, a highly efficacious agent in the treatment of multiple sclerosis (MS), has been tempered by the risks of progressive multifocal leukoencephalopathy associated with its use, and strategies to minimize those risks are of great interest. Extended interval dosing (EID) has been proposed as a way to ...
Rottem Menachem - - 2014
The efficacy of subcutaneous immunotherapy for the treatment of allergic rhinitis, allergic conjunctivitis, allergic asthma and stinging insect hypersensitivity has been demonstrated in several studies. To investigate the effectiveness and side effects of immunotherapy in Israel and the relationship between local and systemic side effects. This retrospective study was based ...
Thomas Karenirene - - 2014
Continuous femoral nerve block infusions (CFNBIs) have been found to both decrease patient postoperative pain and improve postoperative joint mobilization, both of which impact patient satisfaction, outcome, and length of stay. When we began the use of CFNBIs, we needed to create a policy, process, standing order form, and staff ...
Duarte João Jackson JJ Universidade Federal de Mato Grosso do Sul, Campo Grande, MS, - - 2014
Aortic dissection is a cardiovascular event of high mortality if not early diagnosed and properly treated. In Stanford type A aortic dissection, there is the involvement of the ascending aorta, whereas in type B the ascending aorta is not affected. The treatment of type A aortic dissection is mainly surgical. ...
Ergul Z - - 2014
To identify rates of recurrence and hypothyroidism afterhemithyroidectomy for unilateral nodular thyroid diseases andits advantages over bilateral radical resections. Fifty patients who underwent thyroid lobectomy withunilateral thyroid disease were included. Follow-up with thyroidfunction tests on the first month and then once every threemonths, as well as ultrasonography controls once a ...
Narula Ramesh R Assistant Professor, Department of Orthopaedics, Rohilkhand Medical College , Bareilly (UP), India - - 2014
Planter Fasciitis is an annoying and painful condition that limits function. There is pain and tenderness in the sole of the foot, mostly under the heel, with standing or walking and is considered a self limiting condition. Symptoms resolve in 80% to 90% of cases within ten months. However, this ...
Santos Isabel Fonseca IF Bayer Portugal, S.A. Carnaxide. - - 2014
Introduction: Venous thromboembolism is a burden on healthcare systems. The aim of this analysis was to project the long-term costs and outcomes for rivaroxaban compared to standard of care (enoxaparin/warfarin) in Portugal for the treatment and secondary prevention of venous thromboembolism.Material and Methods: A Markov model was developed using event ...
Cicione Antonio A Department of Urology & Research Doctorate Urology Program, Magna Graecia University, Catanzaro, - - 2014
We assess the effectiveness of intravesical instillation of hyaluronic acid (HA) and chondroitin sulphate (CS) as a non-antibiotic treatment option for prophylaxis of recurrent urinary tract infections (UTIs) in female patients. This was a retrospective cohort study involving 7 European institutions. We included patients with recurrent UTIs who received intravesical ...
Sedeh Shirin Amini SA Department of Periodontology, Dental School, Khorasgan (Isfahan) Branch, Islamic Azad University, Isfahan, - - 2014
Cryosurgery is one of the simplest, most effective gingival depigmentation methods. Repigmentation may happen after a while in each method. The aim of this study is to compare the recurrence rate after treatment by liquid nitrogen swap and a cryoprob in 18 months. A total of 26 patients with physiologic ...
Pereira-Lima Júlio C JC Department of Gastroenterology and Hepatology, Santa Casa Hospital/Federal University of Health Sciences of Porto Alegre (UFCSPA), Porto Alegre, Brazil, - - 2014
Postoperative esophageal strictures frequently recur. We assessed the efficacy of injecting triamcinolone after bougie dilation in comparison to dilation alone. In a double-blind randomized fashion, 19 patients (68 % male with mean age of 53-years old) with non-dilated esophagogastric complex strictures after esophagectomy with gastric pull-up were assigned to receive dilation ...
Myers Kevin R KR Department of Orthopaedics, North Shore-Long Island Jewish Medical Center, New Hyde Park, New - - 2014
There are two scaffold products designed for meniscal reconstruction or substitution of partial meniscal defects that are currently available in the Europe: the collagen meniscal implant (CMI; Ivy Sports Medicine, Gräfelfing, Germany) and the polymer scaffold (PS; Actifit, Orteq Bioengineering, London, United Kingdom). The CMI has demonstrated improved clinical outcomes ...
Stone Scellig S D SS Department of Neurosurgery, Boston Children's Hospital, Boston, - - 2014
Object Combined endoscopic third ventriculostomy with choroid plexus cauterization (ETV/CPC) enhances the likelihood of shunt freedom over ETV alone, and thus avoidance of shunt-related morbidity, in hydrocephalic infants. To date, virtually all published reports describe experiences in Africa, thus hampering generalization to other parts of the world. Here, the authors ...
Lorenz Katrin K Johannes Gutenberg-University Mainz, Mainz University Medical Center, Department of Ophthalmology , Langenbeckstr. 1, 55131 Mainz , Germany +49 6131 174069 ; +49 6131 1747 4069 ; - - 2014
Introduction: Lowering intraocular pressure (IOP) is at present the only therapeutic approach to the treatment of glaucoma proven to be successful. The choice of therapy must take into account efficacy, tolerability, safety, quality of life, adherence and cost. Monotherapy fails to achieve a satisfactory IOP reduction in 40 - 75% ...
Kim S A SA Department of Dermatology, Seoul National University College of Medicine, Seoul National University Bundang Hospital, Gyeong-gi, - - 2014
Following the recent elucidation of its pathogenic mechanisms involving reactive oxygen species, use of vitamins, folic acid and antioxidants as adjuvant therapy has been suggested. To evaluate the long-term outcome of childhood facial vitiligo who were treated with nutritional education, vitamin E (α-tocopherol 100-400 IU/day), folic acid (1-2 mg/day) and multivitamin intake ...
Balestri R R Department of Specialized, Clinical and Experimental Medicine, Division of Dermatology, University of Bologna, Bologna, - - 2014
Tuberous sclerosis complex (TSC) is an autosomal dominant neurocutaneous syndrome causing hamartomatous growths in multiple organs. Facial angiofibromas occur in up to 80% of patients and can be highly disfiguring. Treatment for these lesions has historically been challenging. Recently, topical rapamycin has been proposed as an effective option to treat ...
Taveira-DaSilva Angelo M - - 2014
Background.Combined simvastatin and sirolimus therapy reduce TSC2-null lesions and alveolar destruction in a mouse model of lymphangioleiomyomatosis (LAM), suggesting that therapy with both drugs may benefit LAM patients. Methods.To determine whether simvastatin changed the prevalence of adverse events or altered the therapeutic effects of sirolimus, we recorded adverse events and ...
Ernst M M Department of Diagnostic and Interventional Neuroradiology, University Medical Center Hamburg-Eppendorf, Haus Ost 22 (O 22), Martinistr. 52, 20246, Hamburg, Germany, - - 2014
The treatment mode in acute vertebrobasilar occlusion (VBO) remains uncertain. We analyzed efficacy and safety of intravenous glycoprotein IIb/IIIa inhibitor (IV GPI) plus subsequent intra-arterial thrombolysis with or without additional endovascular mechanical therapy (percutaneous transluminal angioplasty/stenting or thrombus aspiration) and sought treatment factors that predict good clinical outcome. We retrospectively ...
Liang Chih-Ming - - 2014
Background: Quinolone-containing triple therapy is recommended as an option for non-bismuth containing second-line Helicobacter pylori eradication. Current available Taiwanese reports in the literature used 7-day quinolone-containing triple therapy. As a result, some physicians still prescribe 7-day regimens in real-world practice in Taiwan. This study aimed to further assess the appropriateness ...
Huizinga T W J TW Department of Rheumatology, Leiden University Medical Center, Leiden, The - - 2014
To assess the efficacy and safety of tocilizumab (TCZ) plus methotrexate/placebo (MTX/PBO) over 2 years and the course of disease activity in patients who discontinued TCZ due to sustained remission. ACT-RAY was a double-blind 3-year trial. Patients with active rheumatoid arthritis despite MTX were randomised to add TCZ to ongoing MTX ...
Reddy Ashvini K AK *Department of Ophthalmology, University of Miami Miller School of Medicine, Bascom Palmer Eye Institute, Miami, Florida; and †Department of Ophthalmology, Emory University, Atlanta, - - 2014
To determine whether serial ranibizumab injections are effective in the treatment of cystoid macular edema in patients with chronic controlled noninfectious uveitis. Five eyes of 5 patients were included in a prospective noncomparative therapeutic trial. They received intravitreal injections of ranibizumab at Day 0 and were followed monthly for 1 ...
Dinglas Victor D VD Johns Hopkins University School of Medicine, Division of Pulmonary and Critical Care Medicine , 1800 East Monument St. , 5th Floor, Pulmonary , Baltimore, Maryland, United States, 21205, Johns Hopkins University, Outcomes After Critical Illness and Surgery (OACIS) Group, Baltimore, Maryland, United States ; - - 2014
Rehabilitation started early during an intensive care unit (ICU) stay is associated with improved outcomes and is the basis for many quality improvement (QI) projects showing important changes in practice. However, little evidence exists regarding whether such changes are sustainable in real-world practice. To evaluate the sustained effect of a ...
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