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Sheedy Kellen C KC Loyola - - 2014
Objective: Injectable osteoporosis drugs are increasing in popularity due to their efficacy and convenient administration. In this retrospective comparison of the two available treatments, denosumab (Prolia®) and zoledronic acid (ZA, Reclast®), we aimed to determine and compare the efficacy and tolerability of denosumab and ZA.Methods: The charts of patients who ...
Poerner Tudor C TC From the 1st Department of Medicine, Division of Cardiology, University Hospital of Jena, Jena, Germany (T.C.P., S.O., J.G., K.N., F.J., B.G., C.J., H.R.F.); and Clinical and Experimental Interventional Cardiology, Internal Medicine III, University of Saarland, Saarbrücken, Germany - - 2014
In this randomized trial, strut coverage and neointimal proliferation of a therapy of bare metal stents (BMSs) postdilated with the paclitaxel drug-eluting balloon (DEB) was compared with everolimus drug-eluting stents (DESs) at 6-month follow-up using optical coherence tomography. We hypothesized sufficient stent coverage at follow-up. A total of 105 lesions ...
Layton Thomas Benjamin TB University of Manchester, United Kingdom. Electronic address: - - 2014
To illustrate the potential side effects and clinical efficacy of Botox injections in treating sialorrhoea. A 26-year-old patient with cerebral palsy with dystonia had a long history of severe, distressing sialorrhoea. She was treated with three separate Botox injections into her salivary glands in December 2011, July 2012 and March ...
Yoon Kichul K Department of Internal medicine, Seoul National University Bundang Hospital, Seongnam, - - 2014
Resistance rates of H. pylori to clarithromycin, metronidazole and quinolone are over 30% in S. Korea. Aim of this prospective study was to evaluate the ultimate eradication rate of H. pylori after 1st, 2nd or 3rd line therapy in Korea. A cohort of 2,202 patients with H. pylori was treated ...
Bano Maria M Emory University School of Medicine and Children's Healthcare of Atlanta, Atlanta, - - 2014
Tricuspid annular plane systolic excursion (TAPSE) has emerged as a novel and reliable measure of right ventricular (RV) function. The purpose of this study was to determine the effect of pulmonary hypertension (PH) therapy on TAPSE in pediatric patients and compare TAPSE to other quantitative measures of RV function. A ...
Chandrasekar Thenappan T UC Davis Medical Center, Urology , 4860 Y Street , Suite 3500 , Sacramento, California, United States, 95817 , 916-816-0711 , 916-734-8094 ; - - 2014
Purpose: We created an internet-based survey of patients treated for urolithiasis to evaluate for trends in treatment, outcomes and patient satisfaction, and to establish internet surveys as a feasible medium for future research of patient urolithiasis treatment experiences. Methods and Materials: We used the website "kidneystoners.org" to disseminate the online ...
Shin Jung U JU Department of Dermatology and Cutaneous Biology Research Institute, Yonsei University College of Medicine, Seoul, South - - 2014
Postoperative scarring after thyroidectomy is a problem for both patients and clinicians. Recently, both non-ablative and ablative fractional laser (NFL and AFL) systems have attracted attention as potential therapies for the revision of thyroidectomy scars. The present split-scar study was designed to directly compare the efficacy of these two methods ...
Gümüş Aziz A Department of Pulmonary Medicine - - 2014
Abstract Purpose: To evaluate the effect of anti-tubercular treatment on retinal nerve fiber layer (RNFL) thickness and the efficiency of optic coherence tomography (OCT) on early diagnosis of optic neuropathy. Methods: Twenty patients diagnosed with either pulmonary or extra-pulmonary tuberculosis which were treated with anti-tubercular treatment (isoniazid (INH), rifampicin, ethambutol ...
Werner-Gibbings Keagan K Department of Vascular Surgery, Royal Prince Alfred Hospital, Sydney, New South Wales, - - 2014
Endovascular interventions are increasingly utilized in managing occlusive peripheral vascular disease. Angioplasty and stenting remain the mainstay of endovascular management; however, newer treatment modalities such as excisional atherectomy provide the clinician with additional treatment options. While demonstrating promising results in available trials, a paucity of data exist regarding peripheral atherectomy. ...
Hashikata Takehiro T Department of Cardiovascular Medicine, Kitasato University School of Medicine, 1-15-1 Kitasato, Minami-ku, Sagamihara, Kanagawa, 252-0374, Japan, - - 2014
Incomplete neointimal coverage and malapposed struts after stenting are associated with increased risk of stent thrombosis. We aimed to evaluate neointimal coverage early after Resolute zotarolimus-eluting stent (R-ZES) implantation using optical coherence tomography (OCT). A total of 20 patients with de novo native coronary lesions with R-ZES were enrolled. Among ...
Mohr Michael M Department of Medicine A, Hematology, Oncology and Pneumology, University Hospital Muenster, Muenster, - - 2014
Recurrent respiratory papillomatosis (RRP) is a primary benign disease, which is characterized by papillomatous growth in the respiratory tract. Malignant transformation occurs in only 3-5% of cases, however, local growth of the benign papillomas is interpreted as clinically malignant in a markedly higher proportion of patients. Local surgical or endoscopic ...
Uchiyama Eduardo E Department of Ophthalmology , Massachusetts Eye and Ear Infirmary, Boston, Massachusetts , USA - - 2014
Abstract Uveitis is a group of inflammatory ocular conditions that cause significant visual morbidity around the world. Many of the cases of blindness secondary to uveitis can be avoided with adequate and aggressive management of the intraocular inflammation. Steroids have been utilized in the treatment of noninfectious uveitis for more ...
Jia Ying Y Department of Obstetrics and Gynecology, First Affiliated Hospital of Chongqing Medical University, Chongqing, China (Y.J., J.W., L.T., M.Lu., M.Lo.); and Department of Pathology, College of Basic Medicine (M.X.), and Biomedical Engineering College (C.L.), Chongqing Medical University, Chongqing, - - 2014
Focused ultrasound waves penetrate superficial tissues and are aimed toward the target tissues at specific depths to exert their biological effects. Focused ultrasound has been applied for a number of clinical indications, including vulval dystrophies and low-grade vulval disease. This study aimed to assess the efficacy and safety of focused ...
Sousa L L Centro Hospitalar e Universitario de Coimbra, Hospitais da Universidade de Coimbra, Coimbra, - - 2014
INTRODUCTION. Studies have shown that natalizumab is an effective treatment for relapsing-remitting multiple sclerosis (RRMS). To date, no data are available in Portuguese patients. AIM. To determine the efficacy and safety of natalizumab in patients with RRMS in routine clinical practice in Portugal. PATIENTS AND METHODS. Clinical data for adult ...
AlGhamdi Khalid - - 2014
A permanent, unpleasant atrophic leishmaniasis scar is a potentially disfiguring condition that causes social stigma with limited treatment choices. Fractionated carbon dioxide (CO2) laser resurfacing is expected to be a safe and effective treatment for leishmaniasis scars. To assess the safety and efficacy of ablative fractional resurfacing (AFR) with a ...
Knösel Michael - - 2014
The occurrence of side-effects of fixed orthodontic therapy, such as white-spot lesions and root resorption, are known to be significantly more frequent with increasing duration of treatment. Multi-bracket treatment should be as short as possible, in order to minimize the risks of collateral damage to teeth. The aim of this ...
Suk Kyung Soo KS Department of Orthopaedic Surgery, Yonsei University College of Medicine, Seoul, - - 2014
Teriparatide markedly increases bone formation and strength, while reducing the incidence of new-onset osteoporotic vertebral compression fractures (OVCFs). In some countries, expenses for teriparatide use are covered by medical insurance for up to 6 months; however, the national medical insurance of the authors' country does not cover these expenses. This ...
Chang Mineok M Department of Cardiology, Asan Medical Center, University of Ulsan College of Medicine, 388-1 Poongnap-dong, Songpa-gu, Seoul, 138-736, - - 2014
Use of dual antiplatelet therapy (DAPT; the combination of aspirin and an inhibitor of platelet P2Y12) is the key pharmacological component in the management of acute coronary syndrome and percutaneous coronary intervention (PCI) with stent implantation, but the optimal treatment duration is still unclear. Although current guidelines recommend prescription of ...
Rubboli Andrea A Division of Cardiology, Laboratory of Interventional Cardiology, Ospedale Maggiore, Largo Nigrisoli 2, 40133 Bologna, Italy. - - 2014
To obtain further, and more focused, information on the efficacy and safety of the antithrombotic regimens, including triple therapy (TT) of warfarin, aspirin, and clopidogrel; dual therapy (DT) of warfarin and single antiplatelet agent (aspirin or clopidogrel); and dual-antiplatelet therapy (DAPT) of aspirin and clopidogrel, prescribed to patients on oral ...
Enk C D CD Department of Dermatology, Hadassah Medical Organization - The Hebrew University Medical School, Jerusalem, - - 2014
Cutanous leishmaniasis (CL) is endemic in Israel with hundreds of new cases reported in recent years. Photodynamic therapy (PDT) is highly effective for CL, but requires equipment only available at specialized treatment centers. Daylight-activated PDT (DA-PDT) abolishes the need for artificial light sources and allows the patient to administer the ...
Lal Niharika Ranjan - - 2014
In spite of the availability of multiple treatment options, viral warts are known for their persistence and recurrence, causing frustration to patients and treating physicians. To study the effectiveness and safety of autoinoculation as a treatment modality in cutaneous warts. A double-blind, placebo-controlled study was carried out. In the treatment ...
Maroo Sneha - - 2014
The need to increase the predictability of periodontal regeneration has encouraged clinicians and researchers to employ cell-stimulating proteins in combination with osteoconductive scaffolds, based on the principles of tissue engineering. The purpose of this clinical and radiographic study was to compare the regenerative potential of the combination of β-tricalcium phosphate ...
Ahluwalia Jusleen J Section of Dermatology, Children's Hospital of Philadelphia, Philadelphia, - - 2014
Administration of intravenous immunoglobulin (IVIG) to patients with Stevens-Johnson syndrome (SJS) has been controversial. The objective of this study was to evaluate the effectiveness of IVIG, systemic corticosteroids, or both in treating Mycoplasma pneumoniae-associated SJS (mpSJS). Retrospective series of 10 pediatric mpSJS cases were stratified into four treatment groups: IVIG ...
Kruger Tiffany L - - 2014
To determine if and when a secondary intraocular lens (IOL) can be beneficial to the successful treatment of a monocular infantile cataract. This retrospective study reviewed medical records of children undergoing treatment of a monocular congenital cataract from 1996 to 2009 at one pediatric ophthalmology practice. Patients had unilateral cataracts ...
Attarbaschi A A Department of pediatric Hematology and Oncology, St. Anna Children's Hospital, Medical University of Vienna, Vienna, - - 2014
Background: Recently, the UK CCLG and COG reported that an intrachromosomal amplification of chromosome 21 (iAMP21) in acute lymphoblastic leukemia (ALL) loses its adverse prognostic impact with intensified therapy. Patient and Methods: We evaluated the prognosis of iAMP21 among patients from the ALL-BFM (Berlin-Frankfurt-Münster) 2000 trial with 46 of 2 637 ...
Palmer A J R AJ University of Oxford, Nuffield Department of Orthopaedics, Rheumatology, and Musculoskeletal Sciences, Windmill Road, Oxford, OX3 7LD, - - 2014
Femoroacetabular Junction Impingement (FAI) describes abnormalities in the shape of the femoral head-neck junction, or abnormalities in the orientation of the acetabulum. In the short term, FAI can give rise to pain and disability, and in the long-term it significantly increases the risk of developing osteoarthritis. The Femoroacetabular Impingement Trial ...
Cárdenas Andrés A GI/Endoscopy Unit, Institut de Malalties Digestives i Metaboliques, Hospital Clinic, University of Barcelona, Villarroel 170, Esc 3-2, Barcelona 08036, Spain. Electronic address: - - 2014
Patients with portal hypertension and esophageal varices are at risk of bleeding due to a progressive increase in portal pressure that may rupture the variceal wall. Appropriate treatment with initial general measures, such as resuscitation, a restrictive transfusion policy, antibiotic prophylaxis, pharmacologic therapy with vasoconstrictors, and endoscopic therapy with endoscopic ...
Zhang Jian-Guo JG Department of Neurosurgery, Beijing Tiantan Hospital, Capital Medical University, Beijing, - - 2014
To evaluate the effectiveness of deep brain stimulation (DBS) of the globus pallidus internus (GPi) on tic severity and common comorbidities in patients with severe Tourette syndrome that is refractory to pharmacological treatment and psychotherapy. We retrospectively assessed the long-term clinical outcomes of 13 patients with treatment-refractory Tourette syndrome who ...
Hamer Jessica J - - 2014
To the Editor: Paliperidone palmitate is a long-acting injectable (LAI) antipsychotic, approved for treatment of schizophrenia in adults. It is the major active metabolite of risperidone and, in its injectable form, has several potential advantages over other LAIs. It reaches steady state within 4 to 8 days, so patients are ...
Hoover William D WD - - 2014
Actinic keratoses (AKs) are on a continuum of progression to squamous cell carcinoma (SCC). The most common AK treatment modalities are lesion-directed cryosurgery and field-directed therapy with 5-fluorouracil (5-FU); however, side effects can affect patient compliance. This study was performed to determine the efficacy and perceived side effects of combination ...
Jeong Hyunsuk H Department of Preventive Medicine, College of Medicine, The Catholic University of Korea, - - 2014
Stem cell-based therapy is a potential new approach in the treatment of stroke. However, the efficacy and safety of these treatments are not yet fully understood. Therefore, we performed a meta-analysis of available single-arm studies using stem cell-based therapy in patients with stroke. We searched MEDLINE, EMBASE, and the Cochrane ...
Kim Sue-Min SM 0000-0002-0894-5207 Department of Plastic & Reconstructive Surgery, Bucheon St. Mary's Hospital, The Catholic University of Korea, Bucheon, - - 2014
To date, few studies have compared the effectiveness of topical silicone gels versus that of silicone gel sheets in preventing scars. In this prospective study, we compared the efficacy and the convenience of use of the 2 products. We enrolled 30 patients who had undergone a surgical procedure 2 weeks ...
Draper David O DO Exercise Science Department, Brigham Young University, Provo, - - 2014
Regaining full, active range of motion (ROM) after trauma to the elbow is difficult. To report the cases of 6 patients who lacked full ROM in the elbow because of trauma. The treatment regimen was thermal pulsed shortwave diathermy and joint mobilizations. Case series. University therapeutic modalities laboratory. Six patients ...
Goyonlo Vahid Mashayekhi VM Department of Dermatology, Cutaneous Leishmaniasis Research Center, School of Medicine, Imam Reza Hospital, School of Medicine, Mashhad University of Medical Sciences, Mashhad, - - 2014
Antimoniate compounds have been used as gold standard treatment for cutaneous leishmaniasis since many years ago, but with increase in incidence of drug as well as individual contraindications, more attention has been given to alternative treatments. The aim of this study was to evaluate the efficacy of intralesional amphotericin B ...
Fernandes-Dias Stephanie Botti SB UNESP - State University of São Paulo, Dept. of Periodontology, College of Dentistry - FOSJC, São José dos Campos, - - 2014
To evaluate the treatment of gingival recession with a connective tissue graft (CTG) alone, or in combination with low-level laser therapy (CTG+L). Forty patients presenting 40 Miller Class I and II gingival recessions were included. The defects were randomly assigned to receive either CTG (n = 20) or CTG+L (n ...
Mangia Alessandra A Liver Unit, IRCCS "Casa Sollievo della Sofferenza", San Giovanni Rotondo, Italy. Electronic address: - - 2014
The uridine nucleotide analogue sofosbuvir is a selective hepatitis C virus NS5B polymerase inhibitor, active regardless of genotype. We analyzed data on efficacy and safety of sofosbuvir, either in combination with pegylated interferon alfa-2a and ribavirin, or in combination with ribavirin alone as part of an interferon free regimen in ...
Antonoglou Georgios N GN Institute of Dentistry, Department of Periodontology and Geriatric Dentistry, University of Oulu, - - 2014
The aim of the present study was to define and evaluate the post-treatment recurrence of unicystic and solid or multicystic ameloblastoma lesions, measured as counts of first time recurrences. A systematic review of the literature and meta-analysis was planned according to the PRISMA statement and in order to include randomized ...
Abu Dabrh Abd Moain AM Division of Preventive, Occupational, and Aerospace Medicine (A.M.A.D., M.H.M.), Mayo Clinic, Rochester Minnesota 55905, Knowledge and Evaluation Research Unit (A.M.A.D., K.M., N.A., W.H.F., Z.W., M.H.F., M.H.M.), Center for the Science of Health Care Delivery, Mayo Clinic, Rochester Minnesota 55905, Library Public Services (L.J.P.), Mayo Clinic, Rochester Minnesota 55905, and Department of Medicine, Division of Endocrinology and Metabolism and Department of Neurosurgery (L.K.), Stanford University School of Medicine, Stanford, California - - 2014
Context: Acromegaly is usually treated with surgery as a first-line treatment, although medical therapy has also been used as an alternative primary treatment. Objective: We conducted a systematic review and meta-analysis to synthesize the existing evidence comparing these two approaches in treatment-naÏve patients with acromegaly. Data Sources: This study performed ...
Bosman E E Medfem Clinic, Bryanston, South - - 2014
Previous reports indicated that hyperinsulinaemic men may exhibit a higher percentage of poorly compacted DNA in their spermatozoa and less success in an IVF programme (Andrologia, 45, 2003, 18; Andrologia, 2014, doi: 10.1111/and.12227). The aim of this study was to investigate the effect of metformin (Glucophage(®) ) and antioxidant treatment ...
Gouëffic Yann - - 2014
Currently, endovascular treatment is indicated to treat femoropopliteal lesions <=15 cm. However, the Achilles' heel of femoropopliteal endovascular repair remains restenosis. Paclitaxel eluting stents have shown promising results to prevent restenosis in femoropopliteal lesions compared to percutaneous transluminal angioplasty. A recently released prospective registry using a newer generation of self-expandable ...
Ebiloglu Turgay T Department of Urology, Etimesgut Military Hospital, Ankara, - - 2014
Enuresis is a child older than 5 years wetting in discrete portions during sleep. It has two subgroups: monosymptomatic enuresis nocturna (MSEN) and non-monosymptomatic enuresis nocturna (NMSEN). In this research, we specifically aimed to examine the effect of biofeedback in NMSEN. We retrospectively analyzed the hospital records of 182 children ...
Coudert Bruno B Department of Medical Oncology, Centre Georges-Francois Leclerc, Dijon, France. Electronic address: - - 2014
An effective and well tolerated treatment is needed for patients with early HER2-positive breast cancer who do not achieve a pathological complete response after neoadjuvant therapy. The AVATAXHER trial aimed to predict pathological complete response early with the use of PET and to investigate whether the addition of bevacizumab could ...
Matsushima Sayomi S Second Division, Department of Internal Medicine, Hamamatsu University School of Medicine, 1-20-1 Handayama, Hamamatsu 431-3192, - - 2014
Combination therapy with a long-acting antimuscarinic agent and a long-acting β2-agonist are recommended in chronic obstructive pulmonary disease (COPD) if control is not adequate with one long-acting bronchodilator alone. We evaluated the effects of indacaterol and tiotropium combination therapy, including the effects of adding indacaterol to tiotropium (indacaterol add-on group) ...
Calaf J J Gynaecology and Obstetrics Department, Santa Creu i Sant Pau Hospital, Barcelona, Spain. Electronic address: - - 2014
To compare the effectiveness and costs associated with first-line medical treatments for chronic heavy menstrual bleeding (HMB) in Spain. A cost-effectiveness analysis was conducted comparing the levonorgestrel-releasing intrauterine system (LNG-IUS) with the estradiol valerate/dienogest multiphase oral contraceptive (E2V/DNG), combined oral contraceptives (COC) and progestins (PROG). Study patients were fertile women ...
Cho Byung-Ki BK Department of Orthopaedic Surgery, College of Medicine, Chungbuk National University, Cheongju, Korea. Electronic address: - - 2014
The present prospective study was conducted to evaluate the clinical outcomes of the new ligament reattachment procedure for chronic lateral ankle instability in high-demand athletes. A total of 24 athletes <30 years old were followed for >2 years after undergoing the modified Brostrom procedure using the suture bridge technique. The clinical evaluation ...
Malas Mahmoud B MB Department of Surgery, The Johns Hopkins University, Baltimore, Maryland2Department of Surgery, Johns Hopkins Bayview Medical Center, Baltimore, - - 2014
To our knowledge, there is no level 1 evidence comparing open bypass with angioplasty and stenting in TransAtlantic Inter-Society Consensus (TASC II) B and C superficial femoral artery lesions. The Revascularization With Open Bypass vs Angioplasty and Stenting of the Lower Extremity Trial (ROBUST) is the first prospective randomized clinical ...
Ingen-Housz-Oro Saskia S Department of Dermatology, Assistance Publique-Hôpitaux de Paris, Henri Mondor Hospital, Créteil, - - 2014
The main component of the first-line treatment of pemphigus vulgaris is high doses of systemic corticosteroids, but adverse effects of these drugs are frequent and sometimes severe. Rituximab has shown effectiveness as a corticosteroid-sparing agent or in case of relapse. To our knowledge, the effectiveness of rituximab as a first-line ...
Mercadante Sebastiano S Pain Relief and Palliative Care Unit, La Maddalena Cancer Center, Via San Lorenzo 312, 90146, Palermo, Italy, - - 2014
The aim of the present study was to assess the long-term tolerability and efficacy of intranasal fentanyl (INFS) in opioid-tolerant patients with breakthrough cancer pain (BTP). A 6 months, observational, prospective, cohort study design was employed to follow advanced cancer patients with BTP receiving INFS under routine clinical practice. Eligible adult ...
Shenoi Rajesh A RA Centre for Blood Research and Department of Pathology and Laboratory Medicine, University of British Columbia, Vancouver, British Columbia V6T 1Z3, - - 2014
Heparin-based anticoagulant drugs have been widely used for the prevention of blood clotting during surgical procedures and for the treatment of thromboembolic events. However, bleeding risks associated with these anticoagulants demand continuous monitoring and neutralization with suitable antidotes. Protamine, the only clinically approved antidote to heparin, has shown adverse effects ...
Tetschke Elisa E From the Department of Orthopaedic Surgery, Otto-von-Guericke University Magdeburg, Magdeburg, - - 2014
This study investigates the clinical effects of autologous conditioned plasma (ACP) injections and low-level laser application as therapy options for chronic lateral epicondylitis. A total of 52 patients with chronic lateral epicondylitis were evaluated in this study; 26 of these patients received three ACP injections and the control group, with ...
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