Search Results
Results 351 - 400 of 1786
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Wittstr?m Elisabeth - - 2010
PURPOSE: To investigate retinal function after reduction of intraocular pressure (IOP) by filtration surgery in patients with medically uncontrolled glaucoma. METHODS: Eleven patients (11 eyes) with medically uncontrolled glaucoma underwent trabeculectomy. Clinical investigation, visual field (testing with standard automated perimetry (SAP-Humphrey), optical coherence tomography (OCT), full-field electroretinography (full-field ERG) and ...
Heijl Anders - - 2009
OBJECTIVE: This article, based on the Early Manifest Glaucoma Trial (EMGT), provides prospective natural history data on progression of glaucomatous field defects in 3 of the most common glaucoma types. DESIGN: Cohort of EMGT patients randomized to the untreated control group and followed up to the time of progression, when ...
Wong Roger - - 2011
Purpose:  To classify the clinical characteristics that might identify patients who may not require next-day follow-up following routine vitreoretinal intervention. Methods:  Prospective case series. Results:  The only statistically significant factors for raised intraocular pressure (IOP) were gas tamponade and preoperative raised IOP. 44.7% (17/38) of patients with preoperative IOP ≥ 20 mmHg had ...
Murdoch I - - 2010
To evaluate the repeatability of clinical decision-making by one glaucoma specialist and determine the influence of intraocular pressure (IOP) variation on those decisions. 40 patients were selected in whom consultant decisions were appropriate concerning management. These notes were reviewed on three separate occasions, each 3 months apart. The final examination ...
Konstas Anastasios G P - - 2010
AIM: To compare 24 h intraocular pressure (IOP) control of morning and evening administered bimatoprost/timolol fixed combination (BTFC) and evening administered bimatoprost in exfoliative glaucoma (XFG). METHODS: One eye of 60 XFG patients was included in this prospective, observer-masked, crossover comparison. Following wash-out, all patients received bimatoprost monotherapy for 6 ...
Okeke Constance O - - 2009
To investigate the impact of an intervention program to improve adherence with topical, once daily therapy for glaucoma. Randomized controlled clinical trial. Sixty-six patients with glaucoma being treated with a prostaglandin analog in 1 or both eyes at the Scheie Eye Institute or Wilmer Eye Institute between November 2006 and ...
Tsuda Mei - - 2009
PURPOSE: We examined the effectiveness of latanoprost for reducing intraocular pressure (IOP) in Japanese patients with normal tension glaucoma (NTG) over a 5-year period. Design: Prospective interventional case series. The patients were classified into 2 groups based on mean IOP. METHODS: A total of 38 patients with NTG were studied ...
Letartre Laurence - - 2009
OBJECTIVE: To assess the efficacy of transconjunctival suturing of the scleral flap in improving hypotony maculopathy resulting from overfiltration after trabeculectomy. DESIGN: Retrospective review. PARTICIPANTS: 35 eyes of 33 patients. METHODS: Patients underwent transconjunctival scleral flap suturing for hypotony maculopathy following trabeculectomy using mitomycin C. The scleral flap was sutured ...
Vasudev Deepta - - 2009
To report 6-month and 1 year outcomes of eyes treated for neovascular glaucoma (NVG) with intravitreal bevacizumab injection and panretinal laser (PRP) compared to those receiving PRP alone. retrospective, consecutive case series. Charts of patients with NVG from retinal ischemia and at least 6 months of follow-up were reviewed. Patients ...
Suominen Sakari - - 2010
PURPOSE: To study the intraocular pressure (IOP)-reducing effect of deep sclerectomy on normal-tension glaucoma (NTG) patients. METHODS: We retrospectively analysed 21 eyes of 18 consecutive NTG patients who had undergone deep sclerectomy with mitomycin-C and a collagen implant. RESULTS: Median (range) preoperative IOP was 15.1 mmHg (9.3-20.8) and median follow-up ...
Saito Yoshiaki - - 2010
This study aimed to investigate the effects of preoperative intravitreal bevacizumab (IVB) on outcomes in trabeculectomy for neovascular glaucoma (NVG). Charts for 52 NVG eyes of 52 consecutive patients who received primary trabeculectomy with mitomycin C (MMC) were reviewed. Postoperative follow-up periods for all patients were > or = 4 ...
Irak-Dersu Inci - - 2010
PURPOSE: To evaluate short- and long-term intraocular pressure (IOP) changes after temporal clear corneal phacoemulsification in normal eyes. METHODs: The charts of 266 consecutive non-glaucoma patients who underwent uneventful cataract surgery were reviewed. We recorded preoperative and postoperative (1 day, 1 week, 1 month, 3 months, 6 months, 1 year ...
Cheng Jin-Wei - - 2010
AIMS: To evaluate the efficacy and tolerability of nonpenetrating filtering surgery in the treatment of patients with open-angle glaucoma. METHODS: Pertinent studies were selected by extensive searches. A total of 17 randomized controlled trials were included in the present meta-analysis. The main outcome measures were risk differences (RDs) of complete ...
Tamcelik N - - 2010
To evaluate the outcomes of combined viscotrabeculotomy-trabeculectomy in patients with refractory developmental glaucoma and to compare the success and complication rates with classical trabeculotomy-trabeculectomy procedure. Patients who were selected for this study had cloudy corneas with a diameter of 13 mm or greater and with an initial intraocular pressure (IOP) ...
Kammer J A - - 2010
AIM: To evaluate the efficacy and safety of replacing latanoprost with another prostaglandin analogue (PGA) in patients with glaucoma or ocular hypertension requiring additional intraocular pressure (IOP) lowering while on latanoprost. METHODS: Prospective, randomised, investigator-masked, multicentre clinical trial. Patients on latanoprost 0.005% monotherapy requiring additional IOP lowering discontinued latanoprost and ...
Januleviciene Ingrida - - 2009
PURPOSE: To compare the effects of latanoprost/timolol (LTFC) versus dorzolamide/timolol (DTFC) fixed combinations on intraocular pressure (IOP), visual function, and retrobulbar blood flow in patients with open-angle glaucoma (OAG). METHODS: This was a prospective, randomized, double masked, parallel study on 30 patients with OAG. All patients received 4 weeks of ...
Wanichwecharungruang Boonsong - - 2009
OBJECTIVE: To evaluate the clinical status of a filtering bleb with visible pigment (intra-bleb pigmentation, IBP), in a case-controlled manner. MATERIAL AND METHOD: Forty-one patients with IBP and 40 patients without visible pigment in blebs (controls) were enrolled from the authors' clinic. All patients underwent either trabeculectomy alone or combined ...
Yip Leonard W - - 2009
BACKGROUND: To describe the efficacy and safety of endoscopic cyclophotocoagulation in Asian patients with glaucoma. METHODS: Retrospective case series. Consecutive cases of endoscopic cyclophotocoagulation performed by one surgeon during the study period were included. Patients' records were reviewed for clinical and demographic factors, treatments, intraocular pressure (IOP), visual acuity and ...
Rush Ryan - - 2009
A 61-year-old woman presented with severe ocular pain 3 months after cataract extraction with intraocular lens placement. After performing a thorough ophthalmic examination, it was determined that neovascular glaucoma was present. The patient underwent implantation of an Ahmed valve (New World Medical, Inc., Rancho Cucamonga, CA) with tube placement into ...
Bhallil Salima - - 2009
To evaluate changes in intraocular pressure (IOP) after clear corneal phacoemulsification (CCP) in normal patients. A prospective study including 273 normal patients selected for cataract extraction by CCP. Intraocular pressure was recorded on the 15(th) day, l(st), 2(nd), 3(rd) month and 6 months after surgery. For statistical analysis, Epi Info ...
Dietlein Thomas S - - 2009
Ongoing demographic changes in Europe are heightening the importance of adequate treatment for glaucoma, a disorder that is markedly more common in the elderly. A selective search for relevant literature, including Cochrane Reviews and the guidelines of the European Glaucoma Society, regarding the topical and surgical treatment of glaucoma. It ...
Khoury Rita R Department of Epidemiology, School of Medicine, University of Alabama at Birmingham, 700 S. 18th Street, Birmingham, AL 35294, - - 2009
To assess the association between Ginkgo biloba extract (GBE) use and glaucoma. Self-reported data on the past 12 months of GBE use and the presence of glaucoma were obtained from the 2002 National Health Interview Survey, a nationally-representative population-based sample. Crude and adjusted associations between GBE use and glaucoma were ...
Varma R - - 2010
AIM: To evaluate differences in diurnal intraocular pressure (IOP) fluctuation in glaucoma/ocular hypertension patients treated with once-daily fixed-combination latanoprost/timolol, once-daily latanoprost or twice-daily timolol. METHODS: In two 6-month, double-masked, parallel-group studies, patients received run-in timolol (2-4 weeks) and randomised (1:1:1) to therapy. IOP was measured three times/day at baseline and ...
Gedde Steven J - - 2009
PURPOSE: To report 3-year results of the Tube Versus Trabeculectomy (TVT) Study. DESIGN: Multicenter randomized clinical trial. METHODS: SETTING: Seventeen clinical centers. STUDY POPULATION: Patients 18 to 85 years of age who had previous trabeculectomy, cataract extraction with intraocular lens implantation, or both and uncontrolled glaucoma with intraocular pressure (IOP) ...
Sultan Marla B - - 2009
Glaucoma is one of the leading causes of visual impairment and blindness. Lowering intraocular pressure (IOP) is the only proven means to slow or halt disease progression among those at higher risk of developing glaucoma and those with early to moderate or more advanced glaucoma. Recent publications have highlighted the ...
Erdurmus Mesut - - 2009
PURPOSE: The aim of the present study was to evaluate the frequency of steroid-induced intraocular pressure (IOP) elevation and/or glaucoma in patients with keratoconus (KCN) compared with patients with Fuchs endothelial dystrophy after penetrating keratoplasty (PK). METHODS: A retrospective review of the medical records of patients with KCN or Fuchs ...
De Feo Fabio - - 2009
OBJECTIVE: To evaluate the efficacy and safety of a stainless steel miniature glaucoma drainage device (Ex-PRESS X200) implanted under a scleral flap for the surgical treatment of primary open-angle glaucoma (POAG). STUDY DESIGN: Clinical, prospective, noncomparative, nonrandomized study. The efficacy and safety were evaluated on the full sample, with a ...
Smith Michael - - 2009
PURPOSE: To examine the results of removal and simultaneous replacement of Ahmed aqueous drainage devices (ADDs), which require removal due to complications. METHODS: Noncomparative retrospective case series of 6 patients. RESULTS: For the period from January 1999 to December 2007, 325 Ahmed ADD insertions were performed in 272 patients. From ...
Plager David A - - 2009
PURPOSE: To describe the safety profile and clinical response on elevated intraocular pressure (IOP) of betaxolol hydrochloride ophthalmic suspension 0.25% (betaxolol) and timolol maleate ophthalmic gel-forming solution (TGFS) (0.25% and 0.5%), in subjects under 6 years of age. METHODS: Subjects were randomized to betaxolol 0.25% (twice daily) or TGFS (daily) ...
Tai M-C - - 2010
To evaluate the efficacy and safety of Ahmed glaucoma valve (AGV) implantation in Asian patients with refractory glaucoma. The study was a retrospective interventional case series conducted at a single institution between January 2004 and January 2006. The study population included 91 patients (91 eyes). A total of 70 patients ...
Sharma P D - - 2010
To compare short- and long-term IOP changes in small incision cataract surgery (SICS) vs conventional extracapsular cataract surgery (CECS). A total of 232 eyes of as many patients undergoing cataract surgery were randomized to SICS or CECS. Sixteen eyes had to be excluded out of the study. IOP was recorded ...
Rahman M Q - - 2009
AIMS: To report the initial findings of a unique database of 956 patients with ocular hypertension (OHT), normal tension glaucoma (NTG) and primary open angle glaucoma (POAG) attending the Glaucoma Clinic at Glasgow Royal Infirmary, Glasgow, UK. METHOD: The database contains retrospective data from 1981 and prospective data from 1999. ...
Bournias Thomas E - - 2009
OBJECTIVE: To compare the efficacy of brimonidine, dorzolamide, and brinzolamide in reducing intraocular pressure (IOP) when used as adjunctive therapy to a prostaglandin analog (PGA). DESIGN: Randomized, controlled, investigator-masked, single-site, parallel-group clinical trial. PARTICIPANTS: One hundred twenty eyes of 120 patients with open-angle glaucoma or ocular hypertension who had inadequate ...
Zanon-Moreno Vicente - - 2009
PURPOSE: This study deals with the role of the topical administration of dorzolamide eyedrops on the oxidative/antioxidant status of aqueous humor in patients with primary open angle glaucoma (POAG). METHODS: A case-control study including 130 patients distributed into three groups was carried out: 1) patients with POAG without dorzolamide instillation ...
Nixon Donald R - - 2009
OBJECTIVE: Fixed combinations of 0.2% brimonidine-0.5% timolol and 2% dorzolamide-0.5% timolol are used to lower intraocular pressure (IOP). The objective of this study was to evaluate the IOP-lowering efficacy and ocular tolerability of brimonidine-timolol compared with dorzolamide-timolol when used as monotherapy or as adjunctive therapy to a prostaglandin analog (PGA) ...
Bowman R J C - - 2010
To investigate visual and intra-ocular pressure (IOP) outcomes of combined cataract and glaucoma surgery at a high-volume centre in East Africa carried out over a 1-year period (2006). A retrospective analysis of patient records. A total of 163 patients were identified. Mean age was 67 years (SD 11, range 21-86 ...
Varma Rohit - - 2009
PURPOSE: To compare latanoprost and timolol with regard to changes in the intervisit intraocular pressure (IOP) range, a measure of long-term IOP fluctuation. DESIGN: Post hoc analysis of three 6-month, multicenter, randomized (1:1), double-masked registration trials of latanoprost (n = 313) vs timolol (n = 318). METHODS: Analyses included patients ...
Kurtz Shimon - - 2009
PURPOSE: Bimatoprost is a potent hypotensive drug used in the treatment of glaucoma or ocular hypertension with lower target intraocular pressure (IOP) than latanoprost. Its most disturbing side effect is conjunctival hyperemia. The authors compared the extent of conjunctival hyperemia in patients receiving bimatoprost as initial therapy with that in ...
Spiegel Detlev - - 2009
PURPOSE: To evaluate the safety and efficacy of the iStent Trabecular Micro-bypass Stent in patients undergoing concurrent cataract and glaucoma surgery. METHODS: Prospective, 24-month, uncontrolled, multicenter, multicountry evaluation of 58 patients with uncontrolled primary open-angle glaucoma (including pseudoexfoliation and pigmentary) and cataract. Patients underwent clear cornea phacoemulsification followed by ab ...
Russo Vincenzo - - 2009
PURPOSE: To compare the efficacy of selective laser trabeculoplasty (SLT) to argon laser trabeculoplasty (ALT) as treatment and retreatment to lower intraocular pressure (IOP) in patients with uncontrolled open-angle glaucoma (OAG) on maximally tolerated medication therapy with a follow-up of 12 months. METHODS: A total of 120 eyes of 120 ...
Baykara Mehmet - - 2009
PURPOSE: The aim of the study was to evaluate the safety and effectiveness of a new technique, two-site bimanual microincisional cataract surgery combined with viscocanalostomy plus deeper sclerectomy (two-site bimanual MICS-VC-DS), in patients with cataract and glaucoma. DESIGN: Noncomparative, interventional case series. METHODS: From December 2005 to October 2007, a ...
See Jovina L S - - 2009
OBJECTIVE: To compare the rates of global and sectoral neuroretinal rim area (NRA) and peripapillary atrophy area (PPAA) change in open-angle glaucoma patients and normal control subjects and to determine the relationship between rates of NRA and PPAA change. DESIGN: Prospective, longitudinal cohort study of cases and controls. PARTICIPANTS AND ...
Goldenfeld Modi - - 2009
BACKGROUND AND OBJECTIVE: To compare the medium-term outcome of titanium:sapphire laser trabeculoplasty (TLT) (SOLX, Inc., Waltham, MA) to argon laser trabeculoplasty (ALT) in patients with uncontrolled open-angle glaucoma. PATIENTS AND METHODS: Thirty-seven patients with open-angle glaucoma who had uncontrolled intraocular pressure and no previous filtration surgery participated. Eighteen patients were ...
Pelit Aysel - - 2009
PURPOSE: To assess accumulation of p53 protein in samples of primary pterygium from people living in two different climatic regions in Turkey. MATERIALS AND METHODS: Group 1 included 101 pterygium specimens from people in Adana located in southern Turkey. Group 2 included 39 pterygium specimens from people in Ankara, located ...
Gupta Viney - - 2009
To prospectively evaluate the effect of 1.25 mg and 2.5 mg intracameral bevacizumab on surgical outcomes of trabeculectomy for neovascular glaucoma (NVG), with primary outcome measures being the regression of neovascularization of iris (NVI) and reduction of intraocular pressure (IOP). Consecutive patients with neovascular glaucoma from December 2006 to March ...
Teng Christopher C - - 2009
To investigate the effect of subconjunctival bevacizumab on primary pterygium. A patient with an inflamed nasal primary pterygium, refractory to artificial tears and naphazoline, was enrolled in this study. After pretreatment with topical proparacaine and moxifloxacin, 0.05 mL of bevacizumab (1.25 mg/0.05 mL) was injected subconjunctivally at the limbus. Clinical ...
Tsai H-Y - - 2009
AIMS: To compare the long-term efficacy and safety of combined trabeculectomy and cataract extraction versus trabeculectomy alone in primary angle-closure glaucoma (PACG). METHODS: Hospital files were retrospectively examined for 99 Chinese PACG patients; 75 patients underwent combined surgery and 24 underwent trabeculectomy alone. Success rates were assessed with the Kaplan-Meier ...
Friedman David S - - 2009
PURPOSE: To identify risk factors for poor adherence to topical once daily therapy for glaucoma. DESIGN: Prospective, observational cohort study. PARTICIPANTS: A total of 196 patients with glaucoma who were being treated with a prostaglandin analog in 1 or more eyes at the Scheie or Wilmer Eye Institutes between August ...
Dupas B - - 2010
To compare the results of deep sclerectomy (DS) and trabeculectomy (TRAB) in the management of uveitic glaucoma. A retrospective chart review was carried out of 41 eyes (38 patients) operated on for uncontrolled uveitic glaucoma, 20 by DS with an implant and 21 by TRAB, with antiproliferative agents in both ...
Hirooka Kazuyuki - - 2009
PURPOSE: To investigate risk factors for developing avascular filtering blebs after primary fornix-based trabeculectomy with mitomycin C (MMC). METHODS: One-year observational case series. Ninety eyes of 90 patients who underwent primary trabeculectomy with MMC and a fornix-based conjunctival flap were examined. The appearance of the filtering bleb was classified at ...
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