Search Results
Results 301 - 350 of 1786
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Duan Xiaoming - - 2010
OBJECTIVE: The aim of this investigation was to evaluate the efficacy of reduction in intraocular pressure (IOP) and complications in ab externo superpulse carbon dioxide laser-assisted trabeculectomy. BACKGROUND: Reduction of IOP remains the immediate goal of glaucoma treatment. Although trabeculectomy has been considered the gold standard for the surgical treatment ...
Imamura Yutaka - - 2010
PURPOSE: The purpose of this study was to investigate the frequency of glaucoma and related conditions in patients with central serous chorioretinopathy (CSC), a condition associated with increased choroidal thickness. METHODS: A case-control study was conducted. Consecutive patients with CSC examined from January 1, 2006, through July 31, 2008, were ...
Thatsnarong Duangdao - - 2010
To evaluate the efficacy and safety of selective laser trabeculoplasty (SLT) as a treatment of primary open angle glaucoma (POAG). In a prospective clinical study, 21 eyes suffering from POAG were treated with SLT over inferior 180 degrees of trabecular meshwork. The intraocular pressure (IOP) was measured before and 1 ...
Uusitalo Hannu - - 2010
PURPOSE: The objective of the study was to compare the long-term efficacy and safety of tafluprost 0.0015% with latanoprost 0.005% eye drops in patients with open-angle glaucoma or ocular hypertension. METHODS: This double-masked, active-controlled, parallel-group, multinational, multicentre, phase III study was conducted at 49 centres in 8 countries. Eligible patients ...
Higginbotham Eve J - - 2010
OBJECTIVE: To assess the efficacy and safety of fixed-combination latanoprost-timolol (FCLT) vs latanoprost or timolol monotherapy. METHODS: This 12-week, randomized, double-masked, parallel-group study included patients with open-angle glaucoma or ocular hypertension treated with a beta-blocker and with baseline intraocular pressure (IOP) of 26 through 36 mm Hg. Following washout, eligible ...
Irshad Farhan A - - 2010
PURPOSE: To measure variations in diameter and location of Schlemm's canal in vivo by ultrasound biomicroscopy. DESIGN: Prospective, single-institution, consecutive case series. PARTICIPANTS: Ninety-four patients with and without glaucoma. METHODS: Under topical anesthesia, an 80-MHz iUltrasound probe (iScience Interventional, Inc., Menlo Park, CA) placed at the 12-o'clock position was used ...
Yamazaki Sei - - 2010
PURPOSE: To investigate the effects of switching to SofZia-preserved travoprost (TRV) on superficial punctate keratopathy (SPK) observed in patients using benzalkonium chloride (BAC)-preserved latanoprost (LAT). METHODS: Patients with either primary open-angle glaucoma or ocular hypertension treated with LAT for at least 1 month who presented with SPK participated in this ...
Sellem Eric - - 2010
BACKGROUND: Given the growing number of ocular hypotensive medications available, it is important to be able to predict a positive response to therapy. The purpose of the present study was to identify predictors of an additional 10% intraocular pressure (IOP) reduction after 12 weeks of treatment with latanoprost/timolol fixed combination ...
Agange Negin - - 2010
To our knowledge, we are reporting the first case of a 59-year-old man who developed recurrent CME with three separate trials of three different prostaglandin class drugs following uncomplicated phacoemulsification with intraocular lens implantation. Despite multiple reports of individual prostaglandin (PG) analogues being suggested as the cause of CME, there ...
Prata Tiago Santos - - 2010
PURPOSE: To report the midterm clinical outcomes of a surgical technique for inserting the silicone tube of a Baerveldt glaucoma implant into the ciliary sulcus in pseudophakic patients. METHODS: Noncomparative, interventional case series in which all glaucoma patients with uncontrolled intraocular pressure (IOP) undergoing Baerveldt glaucoma implant insertion with the ...
Zhong Yisheng - - 2010
To evaluate the visual field protective effect of Erigeron breviscapus (vant.) Hand. Mazz. (EBHM) extract on glaucoma with controlled intraocular pressure (IOP). Forty patients (40 eyes) with primary open-angle glaucoma, visual field defects and a postsurgical IOP of <18 mmHg were enrolled. The EBHM and placebo tablets were given orally ...
Smith Michael - - 2010
PURPOSE: To examine the role of ocular massage during the hypertensive phase after Ahmed valve surgery METHODS: Nonrandomized prospective study. RESULTS: Eighteen patients with intraocular pressure (IOP) above target 1 to 8 weeks after Ahmed glaucoma drainage device surgery underwent digital ocular massage. The mean IOP 1 hour after massage ...
Eldaly Mohamed A - - 2010
PURPOSE: To evaluate the initial efficacy of Pneumatic trabecular bypass (PTB) for open angle glaucoma patients. DESIGN: Prospective case series study. METHODS: Ten eyes of 10 patients meeting the inclusion criteria had been operated for PTB. Patients were evaluated regarding to their intraocular pressure (IOP) and glaucoma medication score. They ...
Denis Philippe - - 2010
BACKGROUND: Prospective, multicenter, randomized, double-masked trials have shown latanoprost instilled once daily to be at least as effective as and generally superior to timolol administered twice daily and to be as effective as other frequently prescribed prostaglandin analogues. This study prospectively assessed the efficacy of latanoprost monotherapy in a large ...
Scuderi Gian Luca - - 2010
PURPOSE: To compare the mydriatic effects of 2% ibopamine and collyrium containing 10% phenylephrine + 0.5% tropicamide and to study the associated drug in patients with ocular pseudoexfoliation (PEX) syndrome. METHODS: This was a prospective, comparative, interventional clinical study. The study group consisted of 20 patients with ocular PEX syndrome. ...
Franckena Martine - - 2010
PURPOSE: To assess the current feasibility of online hyperthermia treatment planning guided steering (HGS) and its current contribution to treatment quality in deep hyperthermia for locally advanced cervical cancer. MATERIALS AND METHODS: 36 patients were randomized to receive either their second and fourth (arm A) or their third and fifth ...
Fallah Mohammad Reza - - 2010
To evaluate clinical outcome(s) and complication(s) of topical bevacizumab (avastin) in patients with impending recurrent pterygium. This prospective clinical trial included 54 consecutive patients (54 eyes), who underwent pterygium surgery with bare sclera and mitomycin, and who were diagnosed with impending recurrent pterygium. Of the 54 patients, 26 received eye ...
Pfeiffer Norbert - - 2010
To assess the safety and efficacy of changing to the travoprost/timolol fixed combination (TTFC) from other mono- or adjunctive therapies. A prospective, open-label, observational cohort of primary open-angle glaucoma and ocular hypertensive patients whose intraocular pressure (IOP) was uncontrolled on prior therapy or was not on target. Patients were changed ...
Schwenn Oliver - - 2010
Prospective, observational studies that enroll large numbers of patients with few exclusion criteria may better reflect actual ongoing clinical experience than randomized clinical trials. Our purpose was to obtain efficacy and safety information from a cohort of subjects exposed to latanoprost/timolol fixed combination (FC) for ≥18 months using a prospective, ...
Kitsos George - - 2010
To determine whether the removal of the inner wall of Schlemm's canal (external trabeculectomy) improves the effectiveness of a modified method of deep sclerectomy (DS), which we will call "reversed" deep sclerectomy (RDS). We conducted a prospective study of two groups of patients. Group A included 22 eyes of 18 ...
Hutnik Cindy - - 2010
To assess the effect of preservative-free dorzolamide-timolol on nonvisual symptoms and intraocular pressure (IOP) in newly diagnosed and untreated patients with open-angle glaucoma or ocular hypertension. This was a prospective, 8-week, open-label, Canadian multicenter study. All patients were treated with preservative-free dorzolamide-timolol formulation. The primary outcome was the change in ...
Diaz-Llopis Manuel - - 2010
To evaluate the efficacy and safety of the pars plana clip (PPC) in the Ahmed valve tube inserted via the pars plana in patients with secondary refractory glaucomas. Prospective and interventional case series that included 10 patients with secondary refractory glaucoma. The pars plana vitrectomy and the implant of the ...
Ogundele Abayomi B - - 2010
The objective of this in vivo study was to compare the incidence of vasodilation in guinea pigs following topical administration of bimatoprost ophthalmic solutions 0.01% and 0.03%. The study comprised 20 guinea pigs assigned to 2 treatment groups (10 per treatment group) to receive either bimatoprost 0.01% or bimatoprost 0.03%. ...
Nordmann Jean-Philippe - - 2010
To identify and characterize treatment compliance profiles of glaucoma patients and evaluate the association with intraocular pressure (IOP). A computerized device (Travalert((R))) that recorded daily instillation times and eye-drop counts was given for 3 months. Patients were declared compliant when at least 2 drops were instilled per day. Compliance rates ...
Kiuchi Yoshiaki - - 2010
To compare the effectiveness of standard revision surgery using mitomycin C (MMC) with revision using amniotic membrane transplantation and MMC for elevated intraocular pressure (IOP) after trabeculectomy. A retrospective, nonrandomized comparative study of 36 eyes of 36 patients with a failed trabeculectomy. Patients were divided into two groups, ie, a ...
Brief Gerrett - - 2010
To assess the efficacy and tolerability of a fixed combination of bimatoprost and timolol (BTFC) in a large patient sample in a clinical setting. In this multicenter, observational, noncontrolled, open-label study, patients (n = 1862) with primary open-angle glaucoma or ocular hypertension were treated with BTFC. Assessments were made at ...
Falck Aura - - 2011
Aim of study:  To follow up prospectively the intraocular pressure (IOP) of healthy eyes with senile cataract undergoing phacoemulsification surgery over a duration of 4 years. Patients and methods:  Thirty-five patients entering first eye cataract surgery had IOP measured by applanation tonometry pre-operatively and on day 1, at 1 month, 6 months, 1 year, ...
Kayikcioglu Ozcan R - - 2010
The objective of this study was to investigate the efficacy and safety of trabeculectomy combined with deep sclerectomy in patients with primary open angled glaucoma (POAG) and to compare the results with those from conventional trabeculectomy. In the study 12 eyes of 10 patients operated with trabeculectomy combined with deep ...
Moodie Jonathan - - 2010
To determine the value of daytime and 24-h phasing in patients treated for progressive glaucoma despite apparently adequate intraocular pressure (IOP) control. A retrospective analysis of a cohort of patients that had undergone either daytime phasing (08:00-18:00) or 24-h phasing was conducted. IOP measurements were compared between those taken in ...
Fakhraie Ghasem - - 2009
PURPOSE: To determine if postoperative topical cyclosporine 0.05% has any beneficial effect following trabeculectomy. METHODS: This was an interventional, randomized, prospective, double-masked clinical trial of 44 consecutive patients with uncontrolled glaucoma requiring filtration surgery. Ocular surface disease index questionnaire and comprehensive ocular exam, including Schirmer's tear test 1, were performed. ...
Lee Yeon-Hee - - 2009
OBJECTIVE: We sought to find predictive factors for favourable postoperative intraocular pressure (IOP) after cataract surgery in patients with primary open-angle glaucoma (POAG) and primary angle-closure glaucoma (PACG). STUDY DESIGN: Retrospective evaluation of patients who had undergone cataract surgery. PARTICIPANTS: Forty-eight patients with POAG and 48 patients with PACG. METHODS: ...
Nguyen Quang H - - 2009
PURPOSE: To evaluate intraocular pressure (IOP) and ocular allergy after replacement of 1 of 2 adjunctive therapy regimens (fixed-combination dorzolamide/timolol or dorzolamide/timolol plus brimonidine) with fixed-combination brimonidine/timolol in glaucoma patients treated with ongoing prostaglandin analog (PGA) therapy. METHODS: This prospective, nonrandomized, open-label study involved patients on dorzolamide 2%/timolol 0.5% and ...
Singh D - - 2009
To investigate the effect of topical prostaglandin analogue use on the efficacy of selective laser trabeculoplasty (SLT) intraocular pressure (IOP) lowering in patients with open-angle glaucoma.Patients and This retrospective study included 123 consecutive patients who underwent 180 degrees SLT for the first time. Eyes were grouped into those that received ...
Hamid Mohammad - - 2009
OBJECTIVE: To report 4 cases of recurrent anterior uveitis occurring 1-11 months after trabeculectomy with mitomycin C. DESIGN: Observational case series. PARTICIPANTS: Four patients in whom recurrent uveitis developed after trabeculectomy with mitomycin C, followed at Maisonneuve-Rosemont Hospital in Montreal, Quebec. METHODS: Retrospective review of the medical records. RESULTS: One ...
Fraunfelder Frederick W - - 2009
PURPOSE: To report a case series of conjunctival lymphangiectasia treated with liquid nitrogen cryotherapy. METHODS: A 1.5-mm Brymill cryoprobe was applied in a double freeze-thaw method after an incisional biopsy of a portion of the conjunctiva in patients with conjunctival lymphangiectasia. Freeze times were 1 to 2 seconds with thawing ...
Lee Kyoungsook - - 2009
To evaluate the efficacy of excision of avascular bleb and advancement of adjacent conjunctiva (EBAC) for treatment of hypotony after trabeculectomy with mitomycin C (MMC). Fifteen patients (17 eyes) who received EBAC for correction of hypotony between September 1996 and October 2008 were reviewed retrospectively. The main outcomes were intraocular ...
Alvarado Jorge A - - 2009
To determine whether selective laser trabeculoplasty (SLT) and prostaglandin analogues (PGAs) have a common mechanism of action that involves increasing conductivity across Schlemm's canal endothelial cells (SCEs) and inducing a similar decrease in intraocular pressure (IOP) in a given patient. The intercellular junctions in SCEs were made visible by transfection ...
Netland Peter A - - 2009
To evaluate the results of Ahmed glaucoma valve surgery in neovascular glaucoma and control patients. In this retrospective comparative study, we reviewed 76 eyes of 76 patients, comparing the surgical outcomes in control patients (N=38) to matched neovascular glaucoma patients (N=38). Success was defined as intraocular pressure (IOP) > or ...
Ollikainen Minna L - - 2011
Purpose:  To investigate the efficacy and safety of mitomycin C (MMC)-augmented deep sclerectomy with implant (DSCI) in primary open-angle glaucoma (POAG) and exfoliation glaucoma (ExG) patients. Methods:  A total of 68 eyes of 68 patients with POAG and ExG were enrolled consecutively to undergo DSCI with MMC (0.4 mg/ml for 2 min). ...
Veen Egbert J D - - 2010
Not much is known about the side effects of mitomycin C (MMC), an anti-fibrogenetic agent, in the upper aerodigestive tract. However, its use in ophthalmology is widely known and without quantitatively important side effects. A literature review was performed for side effects of MMC in the upper aerodigestive tract. Forty-six ...
Fristr?m Bj?rn - - 2010
PURPOSE: To compare the effect of time on therapy, efficacy, tolerability and resource utilization of latanoprost or non-prostaglandin analogues (non-PGs) in patients who required a change in intraocular pressure (IOP)-lowering monotherapy. METHODS: This open-label, multicentre study (Sweden, 19 sites; Finland, seven sites) included adults with glaucoma or ocular hypertension with ...
Vuori Marja-Liisa - - 2010
PURPOSE: To evaluate the efficacy of Molteno aqueous shunt as a primary surgical treatment in uveitic glaucoma. METHODS: Nonrandomized, interventional, retrospective clinical study. The intraocular pressure (IOP), survival rate and complications were analyzed in 30 patients with uveitic glaucoma treated with Molteno implant. RESULTS: The mean follow-up time was 59.3 ...
Papaconstantinou Dimitris - - 2010
PURPOSE: To present the preliminary results of our study comparing the outcomes of trabeculectomy with or without OloGen implant in patients requiring glaucoma surgery for uncontrolled intraocular pressure (IOP). METHODS: Forty eyes of 40 patients were assigned randomly to undergo trabeculectomy either with OloGen implant (study group) or without implant ...
Fernandes Bruno F - - 2010
PURPOSE: To report the experience of the Princess Margaret Hospital/University Health Network with the treatment of iris melanoma (IM) with (125)Iodine plaque brachytherapy. DESIGN: Retrospective noncomparative case series. METHODS: All cases of IM submitted to (125)Iodine plaque radiotherapy were included. Patients' demographic, clinical, management, and follow-up data were reviewed. Outcome ...
Stalmans Ingeborg - - 2009
PURPOSE: The aims of this study were: (1) to determine the intra-subject and inter-observer variability of color Doppler imaging (CDI) measurements and readings of the retrobulbar blood vessels, (2) to compare the difference invariability of CDI parameters in non-glaucomatous controls versus glaucoma patients, and (3) to provide calculations of minimum ...
Alwitry Amar - - 2009
PURPOSE: To present outcome data on low risk primary trabeculectomy augmented with low dose peroperative (0.1 mg/mL for 1 minute) mitomycin-C (MMC). METHODS: Retrospective case note review. All cases of trabeculectomy utilizing MMC augmentation at a concentration of 0.1 mg/mL with an application time of 1 minute and at least ...
Gonzalez Anne V - - 2010
BACKGROUND: Topical and systemic corticosteroids are well known to raise intra-ocular pressure while the effect of inhaled corticosteroids (ICS) on the risk of glaucoma remains uncertain. We sought to determine the risk of new onset ocular hypertension or glaucoma requiring treatment, associated with the use of ICS in elderly patients ...
Nordmann Jean-Philippe - - 2009
PURPOSE: To measure the impact of the Xal-Ease delivery device on ease of eyedrop administration and on treatment compliance and satisfaction. METHODS: This prospective, multicenter, randomized, comparative, crossover study was conducted at 43 sites in France. Eligible subjects were >18 years of age, were diagnosed with primary open-angle glaucoma or ...
Suzuki Hisaharu - - 2009
PURPOSE: To directly measure intraocular pressure (IOP) in simulated phacoemulsification and to assess the usefulness of lowering the bottle height in protecting the corneal endothelium in clinical phacoemulsification. SETTING: Nippon Medical School Hospital, Tokyo, Japan. METHODS: Simulated phacoemulsification was performed in porcine eyes with 2 bottle heights, 65.0 cm (BH ...
Ciftci Suleyman - - 2009
To evaluate the clinical efficacy of intravitreal bevacizumab (IVB) combined with panretinal photocoagulation in patients with open angle neovascular glaucoma (NVG). Nine patients (9 eyes) with NVG participated in this study. Patients received IVB (1.25 mg) as the initial treatment for NVG and were followed up for at least 4 ...
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