Search Results
Results 251 - 300 of 1761
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Bazzazi N - - 2010
This study aimed at comparing the results of the Conjunctival Autograft Technique (CAG) and Minimally Invasive Pterygium Surgery (MIPS) in primary pterygium excisions. This was a prospective randomized clinical study performed during a one-year period (2009-2010). One hundred and twenty two patients with primary pterygium were randomized in 2 groups: ...
Bozkurt M K - - 2010
To evaluate the efficacy of topical mitomycin in providing the patency of the neochoanae in children undergoing transnasal endoscopic congenital choanal atresia (CA) repair. A retrospective analysis of surgical results in CA patients who were treated in Selcuk University, Meram Medical Faculty, Department of Otolaryngology between November 2002 and November ...
Breusegem Christophe - - 2010
PURPOSE: To investigate the benefit of preoperative treatment with either topical nonsteroidal anti-inflammatory drug (NSAID) or steroid in terms of clinical outcomes following trabeculectomy. DESIGN: Prospective, randomized placebo-controlled trial. PARTICIPANTS: Sixty-one patients. METHODS: Between July 2005 and October 2007, 61 consecutive medically uncontrolled glaucoma patients scheduled for first-time trabeculectomy were ...
Hermann Manuel Marcel - - 2010
The success of many medical treatments is built on compliance. Electronic monitoring is the most accurate tool to quantify compliance by measuring adherence. In order to assess the efficiency of a recently introduced miniature monitoring device for eye drop application, we evaluated adherence in ophthalmic patients undergoing post-operative short-term topical ...
Zhou Alysia W - - 2010
OBJECTIVE: To determine whether preoperative anterior chamber angle width, captured by anterior segment optical coherence tomography (AS-OCT), can be a predictor of intraocular pressure (IOP) change following cataract surgery. DESIGN: Prospective comparative observational study. PARTICIPANTS: Fifty-three eyes of 53 patients awaiting cataract surgery were included. METHODS: Measurement of anterior chamber ...
Tan Anna M - - 2010
BACKGROUND: Transscleral diode laser cyclophotocoagulation (TSCPC) is an established method of treatment for refractory glaucoma, but is associated with significant complications. This study evaluates the efficacy and safety of a new form of TSCPC using micropulse diode laser and trans-pars plana treatment with a novel contact probe. METHODS: Prospective interventional ...
Stewart William C - - 2010
PURPOSE: To compare the change in 24-h fluctuation of the intraocular pressure (IOP) from various medical therapies in patients with ocular hypertension, primary open-angle (POAG), or exfoliative glaucoma (XFG). METHODS: A meta-analysis of published studies that were controlled, prospective, and comparative trials. Based on study requirements for an objective fluctuation ...
Aponte Elisabeth P - - 2010
To describe the incidence and clinical characteristics of childhood glaucoma in a defined population of the United States. The medical records of all pediatric patients younger than 20 years living in Olmstead County, Minnesota, from January 1, 1965, through December 31, 2004, who met diagnostic criteria for glaucoma or glaucoma ...
Ang Ghee Soon - - 2010
PURPOSE: To determine the effect of cataract extraction on the glaucoma progression index (GPI) in glaucoma patients with coexisting cataract. PATIENTS AND METHODS: This is a retrospective noncomparative study. Consecutive eligible patients with glaucoma who underwent phacoemulsification alone or in combination with augmented trabeculectomy were included. All patients had Swedish ...
Kashkouli Mohsen Bahmani - - 2010
PURPOSE: To compare the anatomical pattern of lacrimal drainage system obstruction (LDSO) associated with topical anti-glaucoma medications (AGM) with a control group. METHODS: In a cross-sectional controlled study, case group included patients on topical anti-glaucoma medications and control group included patients with no history of glaucoma, free of ocular disease, ...
Katz L Jay - - 2010
PURPOSE: To evaluate the intraocular pressure (IOP)-lowering efficacy and safety of ophthalmic formulations of bimatoprost 0.01% and 0.0125% compared with bimatoprost 0.03%. DESIGN: Prospective, randomized, double-masked, multicenter clinical trial. METHODS: Patients with glaucoma or ocular hypertension were randomized to receive once-daily bimatoprost 0.01% (n = 186), bimatoprost 0.0125% (n = ...
Sohn Sae Woon - - 2010
PURPOSE: To evaluate the influence of the extent of myopia on the progression rate of normal-tension glaucoma (NTG). DESIGN: Retrospective, observational case series. METHODS: One hundred forty-three eyes of 143 patients with NTG who were treated from 1994 through 2006 and followed up with standard automated perimetry were evaluated in ...
Fernández-Barrientos Yolanda - - 2010
PURPOSE. To evaluate the changes in aqueous humor dynamics and the efficacy and safety of the iStent (Glaukos Corp., Laguna Hills, CA), in combination with cataract surgery. METHODS. This investigation was a prospective, randomized, clinical study in patients with open-angle glaucoma or ocular hypertension who were undergoing cataract surgery. Aqueous ...
Matzkin Haim - - 2012
Preoperative planning (PP) and intraoperative planning (IoP) are established (125)I-brachytherapy techniques for the treatment of localized prostate cancer. We prospectively compared the effects of each method on reducing PSA levels. One hundred eighty patients treated with brachytherapy as monotherapy without neoadjuvant androgen deprivation therapy or external beam radiation using PP ...
Kobelt Gisela - - 2010
To investigate long-term resource consumption and clinical outcome of patients with early primary open-angle glaucoma or ocular hypertension treated with prostaglandins in clinical practice in France. Thirty-four geographically spread specialized hospitals and private practices enrolled consecutive patients receiving, for the first time, a prostaglandin, alone or in combination. The study ...
Nassiri Nader - - 2010
PURPOSE: To compare 1-site and 2-site phacotrabeculectomies with regard to visual acuity, intraocular pressure (IOP) control, antiglaucoma medication requirements, and postoperative complications. METHODS: In a randomized controlled trial, 169 eyes with coexisting visually significant cataract and glaucoma were randomly allocated into 2 groups: eyes that had a trabeculectomy in a ...
Orme M - - 2010
OBJECTIVES: Primary open-angle glaucoma (POAG) is a chronic condition characterised by optic neuropathy and vision loss. Elevated intraocular pressure (IOP) can damage the optic nerve and is a risk factor for glaucoma, thus treatment usually comprises topical hypotensives. This analysis aims to address methodological issues associated with the synthesis of ...
Rossi Gemma Caterina Maria - - 2010
OBJECTIVE: To assess adherence in glaucoma patients using the Travatan Dosing Aid (TDA); to record differences in adherence by age, sex, therapy, systemic therapies, years from diagnosis, type of therapy and intraocular pressure (IOP). RESEARCH DESIGN AND METHODS: Sixth-month cohort study; fifty-six Caucasian, primary open-angle glaucoma patients on travoprost (T) ...
Guedes Ricardo Augusto Paletta - - 2010
BACKGROUND AND OBJECTIVE:Phaco non-penetrating deep sclerectomy (PhacoNPDS) is an option to simultaneously treat cataract and glaucoma. The authors assessed tensional success of PhacoNPDS and NPDS up to 3 years of follow-up. PATIENTS AND METHODS:A longitudinal consecutive retrospective study was conducted comparing 376 eyes undergoing NPDS (group 1) and 87 eyes ...
Yamashita Takehiro - - 2010
To evaluate the ocular hypertensive response to repetitive cycles of high-dose systemic corticosteroid in young patients with acute lymphoblastic leukemia (ALL). Five patients up to 6 years of age with ALL who received chemotherapy between November 2003 and March 2005 were examined. As maintenance therapy, they received oral or intravenous ...
Raum C - - 2010
BACKGROUND: The purpose of this study was to investigate whether digital planimetry is appropriate for quantification of neuroretinal rim loss in patients with glaucoma, with and without progression. PATIENTS AND METHODS: The optic discs of 44 patients, whose illness had been well documented with photographs over a period of at ...
Fea Antonio M - - 2010
PURPOSE: To compare phacoemulsification alone and phacoemulsification with micro-bypass stent implantation in eyes with primary open-angle glaucoma. SETTING: Instituto di Fisiopatologia Clinica, Clinica Oculistica, Universita' di Torino, Torino, Italy. METHODS: In this prospective double-masked randomized clinical trial, patients had phacoemulsification alone (control group) or phacoemulsification with iStent implantation (combined group). ...
Alemu Abiye M - - 2010
PURPOSE: To determine the incidence of progression of primary open-angle glaucoma at individual levels of mean intraocular pressure (IOP) in patients in Ethiopia. METHODS: A retrospective, multicenter, cohort analysis of patient records with at least 5 years of potential follow-up were evaluated for risk factors associated with progressive optic disc ...
Kandavel Rom - - 2010
PURPOSE: To evaluate the impact of Hispanic and white ethnicity on the recurrence rates of pterygia after primary excision and conjunctival autograft (CAG) in a southern California population. METHODS: A retrospective case-control review comparing 15 Hispanic and 11 white patients with primary nasal pterygia was performed. All participants received pterygium ...
Shahid Humma - - 2010
PURPOSE: To determine whether the use of postoperative subconjunctival 5-fluorouracil (5-FU) reduces the risk of trabeculectomy bleb failure after uncomplicated small incisional cataract surgery. METHODS: Twenty-five consecutive patients with primary open-angle glaucoma and a functioning trabeculectomy bleb and who underwent uncomplicated phacoemulsification surgery were given subconjunctival injections of 5 mg ...
Traverso Carlo E - - 2010
PURPOSE: Tafluprost is a novel prostaglandin F(2alpha)-receptor agonist shown to lower intraocular pressure (IOP) in healthy humans and patients with elevated IOP. We investigated the efficacy, safety, and tolerability of tafluprost 0.0015% compared with latanoprost 0.005% in patients with primary open-angle glaucoma, exfoliation glaucoma, or ocular hypertension. METHODS: This was ...
Duan Xiaoming - - 2010
OBJECTIVE: The aim of this investigation was to evaluate the efficacy of reduction in intraocular pressure (IOP) and complications in ab externo superpulse carbon dioxide laser-assisted trabeculectomy. BACKGROUND: Reduction of IOP remains the immediate goal of glaucoma treatment. Although trabeculectomy has been considered the gold standard for the surgical treatment ...
Imamura Yutaka - - 2010
PURPOSE: The purpose of this study was to investigate the frequency of glaucoma and related conditions in patients with central serous chorioretinopathy (CSC), a condition associated with increased choroidal thickness. METHODS: A case-control study was conducted. Consecutive patients with CSC examined from January 1, 2006, through July 31, 2008, were ...
Thatsnarong Duangdao - - 2010
To evaluate the efficacy and safety of selective laser trabeculoplasty (SLT) as a treatment of primary open angle glaucoma (POAG). In a prospective clinical study, 21 eyes suffering from POAG were treated with SLT over inferior 180 degrees of trabecular meshwork. The intraocular pressure (IOP) was measured before and 1 ...
Uusitalo Hannu - - 2010
PURPOSE: The objective of the study was to compare the long-term efficacy and safety of tafluprost 0.0015% with latanoprost 0.005% eye drops in patients with open-angle glaucoma or ocular hypertension. METHODS: This double-masked, active-controlled, parallel-group, multinational, multicentre, phase III study was conducted at 49 centres in 8 countries. Eligible patients ...
Higginbotham Eve J - - 2010
OBJECTIVE: To assess the efficacy and safety of fixed-combination latanoprost-timolol (FCLT) vs latanoprost or timolol monotherapy. METHODS: This 12-week, randomized, double-masked, parallel-group study included patients with open-angle glaucoma or ocular hypertension treated with a beta-blocker and with baseline intraocular pressure (IOP) of 26 through 36 mm Hg. Following washout, eligible ...
Irshad Farhan A - - 2010
PURPOSE: To measure variations in diameter and location of Schlemm's canal in vivo by ultrasound biomicroscopy. DESIGN: Prospective, single-institution, consecutive case series. PARTICIPANTS: Ninety-four patients with and without glaucoma. METHODS: Under topical anesthesia, an 80-MHz iUltrasound probe (iScience Interventional, Inc., Menlo Park, CA) placed at the 12-o'clock position was used ...
Yamazaki Sei - - 2010
PURPOSE: To investigate the effects of switching to SofZia-preserved travoprost (TRV) on superficial punctate keratopathy (SPK) observed in patients using benzalkonium chloride (BAC)-preserved latanoprost (LAT). METHODS: Patients with either primary open-angle glaucoma or ocular hypertension treated with LAT for at least 1 month who presented with SPK participated in this ...
Sellem Eric - - 2010
BACKGROUND: Given the growing number of ocular hypotensive medications available, it is important to be able to predict a positive response to therapy. The purpose of the present study was to identify predictors of an additional 10% intraocular pressure (IOP) reduction after 12 weeks of treatment with latanoprost/timolol fixed combination ...
Agange Negin - - 2010
To our knowledge, we are reporting the first case of a 59-year-old man who developed recurrent CME with three separate trials of three different prostaglandin class drugs following uncomplicated phacoemulsification with intraocular lens implantation. Despite multiple reports of individual prostaglandin (PG) analogues being suggested as the cause of CME, there ...
Prata Tiago Santos - - 2010
PURPOSE: To report the midterm clinical outcomes of a surgical technique for inserting the silicone tube of a Baerveldt glaucoma implant into the ciliary sulcus in pseudophakic patients. METHODS: Noncomparative, interventional case series in which all glaucoma patients with uncontrolled intraocular pressure (IOP) undergoing Baerveldt glaucoma implant insertion with the ...
Zhong Yisheng - - 2010
To evaluate the visual field protective effect of Erigeron breviscapus (vant.) Hand. Mazz. (EBHM) extract on glaucoma with controlled intraocular pressure (IOP). Forty patients (40 eyes) with primary open-angle glaucoma, visual field defects and a postsurgical IOP of <18 mmHg were enrolled. The EBHM and placebo tablets were given orally ...
Smith Michael - - 2010
PURPOSE: To examine the role of ocular massage during the hypertensive phase after Ahmed valve surgery METHODS: Nonrandomized prospective study. RESULTS: Eighteen patients with intraocular pressure (IOP) above target 1 to 8 weeks after Ahmed glaucoma drainage device surgery underwent digital ocular massage. The mean IOP 1 hour after massage ...
Eldaly Mohamed A - - 2010
PURPOSE: To evaluate the initial efficacy of Pneumatic trabecular bypass (PTB) for open angle glaucoma patients. DESIGN: Prospective case series study. METHODS: Ten eyes of 10 patients meeting the inclusion criteria had been operated for PTB. Patients were evaluated regarding to their intraocular pressure (IOP) and glaucoma medication score. They ...
Denis Philippe - - 2010
BACKGROUND: Prospective, multicenter, randomized, double-masked trials have shown latanoprost instilled once daily to be at least as effective as and generally superior to timolol administered twice daily and to be as effective as other frequently prescribed prostaglandin analogues. This study prospectively assessed the efficacy of latanoprost monotherapy in a large ...
Scuderi Gian Luca - - 2010
PURPOSE: To compare the mydriatic effects of 2% ibopamine and collyrium containing 10% phenylephrine + 0.5% tropicamide and to study the associated drug in patients with ocular pseudoexfoliation (PEX) syndrome. METHODS: This was a prospective, comparative, interventional clinical study. The study group consisted of 20 patients with ocular PEX syndrome. ...
Franckena Martine - - 2010
PURPOSE: To assess the current feasibility of online hyperthermia treatment planning guided steering (HGS) and its current contribution to treatment quality in deep hyperthermia for locally advanced cervical cancer. MATERIALS AND METHODS: 36 patients were randomized to receive either their second and fourth (arm A) or their third and fifth ...
Fallah Mohammad Reza - - 2010
To evaluate clinical outcome(s) and complication(s) of topical bevacizumab (avastin) in patients with impending recurrent pterygium. This prospective clinical trial included 54 consecutive patients (54 eyes), who underwent pterygium surgery with bare sclera and mitomycin, and who were diagnosed with impending recurrent pterygium. Of the 54 patients, 26 received eye ...
Pfeiffer Norbert - - 2010
To assess the safety and efficacy of changing to the travoprost/timolol fixed combination (TTFC) from other mono- or adjunctive therapies. A prospective, open-label, observational cohort of primary open-angle glaucoma and ocular hypertensive patients whose intraocular pressure (IOP) was uncontrolled on prior therapy or was not on target. Patients were changed ...
Schwenn Oliver - - 2010
Prospective, observational studies that enroll large numbers of patients with few exclusion criteria may better reflect actual ongoing clinical experience than randomized clinical trials. Our purpose was to obtain efficacy and safety information from a cohort of subjects exposed to latanoprost/timolol fixed combination (FC) for ≥18 months using a prospective, ...
Kitsos George - - 2010
To determine whether the removal of the inner wall of Schlemm's canal (external trabeculectomy) improves the effectiveness of a modified method of deep sclerectomy (DS), which we will call "reversed" deep sclerectomy (RDS). We conducted a prospective study of two groups of patients. Group A included 22 eyes of 18 ...
Hutnik Cindy - - 2010
To assess the effect of preservative-free dorzolamide-timolol on nonvisual symptoms and intraocular pressure (IOP) in newly diagnosed and untreated patients with open-angle glaucoma or ocular hypertension. This was a prospective, 8-week, open-label, Canadian multicenter study. All patients were treated with preservative-free dorzolamide-timolol formulation. The primary outcome was the change in ...
Diaz-Llopis Manuel - - 2010
To evaluate the efficacy and safety of the pars plana clip (PPC) in the Ahmed valve tube inserted via the pars plana in patients with secondary refractory glaucomas. Prospective and interventional case series that included 10 patients with secondary refractory glaucoma. The pars plana vitrectomy and the implant of the ...
Ogundele Abayomi B - - 2010
The objective of this in vivo study was to compare the incidence of vasodilation in guinea pigs following topical administration of bimatoprost ophthalmic solutions 0.01% and 0.03%. The study comprised 20 guinea pigs assigned to 2 treatment groups (10 per treatment group) to receive either bimatoprost 0.01% or bimatoprost 0.03%. ...
Nordmann Jean-Philippe - - 2010
To identify and characterize treatment compliance profiles of glaucoma patients and evaluate the association with intraocular pressure (IOP). A computerized device (Travalert((R))) that recorded daily instillation times and eye-drop counts was given for 3 months. Patients were declared compliant when at least 2 drops were instilled per day. Compliance rates ...
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