Search Results
Results 251 - 300 of 1795
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Rueth Natasha M - - 2011
Oxaliplatin (OX) is increasingly used for hyperthermic intraperitoneal chemotherapy (HIPC) for patients with peritoneal metastases. Our aim was to review electrolyte disturbances and complications after HIPC with oxaliplatin (OX) versus mitomycin C (MMC). We included patients enrolled in single-institution prospective clinical trials who underwent cytoreductive surgery and HIPC with MMC ...
Jonisch Jonathan - - 2010
PURPOSE: To evaluate the short-term safety and efficacy of topical preservative-free dexamethasone 0.01% for the treatment of ocular surface disease and/or tearing refractory to conventional treatments. METHODS: Retrospective chart review of all patients who received topical unpreserved dexamethasone 0.01% (Leiters Pharmacy, San Jose, CA). Follow-up visits were reviewed for subjective ...
Araie Makoto - - 2010
PURPOSE: To estimate the deterioration rates of visual field loss in Japanese normal-tension glaucoma (NTG) patients under either topical nipradilol or timolol, and to explore intergroup differences in the treatment results. METHODS: A total of 146 NTG patients with mild to moderate damage were randomized to either nipradilol or timolol ...
García-Feijoó Julián - - 2010
OBJECTIVE: To compare brimonidine/timolol fixed combination (BrTFC; Combigan *) with dorzolamide/timolol fixed combination (DTFC; Cosopt dagger) in terms of ability to lower intraocular pressure (IOP) in primary open-angle glaucoma (POAG). METHODS: This was a prospective, randomized, double-masked, crossover study. After 6 weeks of therapy with timolol maleate 0.5% twice daily, ...
Palmberg Paul - - 2010
To evaluate the efficacy and safety of fixed combination latanoprost/timolol versus latanoprost or timolol monotherapy. This 12-week, randomized, double-masked study was designed to overcome potential shortcomings of previous trials. We enrolled 788 subjects with open-angle glaucoma or ocular hypertension treated with a beta-blocker for > or = 4 weeks before ...
Ramli N - - 2010
Recent studies have advocated the use of laser iridoplasty or paracentesis in the initial management of patients with acute primary angle closure (APAC). The aim of this study was to ascertain the effectiveness of medical treatment consisting of topical and systemic intraocular pressure (IOP)-lowering agents in the initial management of ...
Aristeidou Antonios P - - 2011
To evaluate and compare the recorded IOP values of the Pascal dynamic contour tonometer (PDCT) and the Goldmann applanation tonometer (GAT) after photorefractive keratectomy (PRK) and laser in situ keratomileusis (LASIK). Three groups of 84, 182 and 43 patients each were treated by PRK for myopia, LASIK for myopia and ...
Bissig Alexandre - - 2010
The efficacy and safety of a newly designed Ex-PRESS X-200 drainage device for the surgical treatment of glaucoma was evaluated. A clinical, prospective, monocentric, non-randomised, unmasked study on patients with medically uncontrolled glaucoma was performed. A superficial scleral flap was created. A posterior deep sclerectomy (DS) was dissected without opening ...
Kahook Malik Y - - 2010
PURPOSE: To investigate outcomes after trabeculectomy using intraoperative intravitreal ranibizumab and topical mitomycin C (MMC) vs MMC alone. DESIGN: Prospective randomized single-site pilot study. METHODS: Patients diagnosed with primary open-angle glaucoma were randomized 1:1 to either combination intravitreal ranibizumab 0.5 mg and topically applied MMC (0.4 mg/mL for 2 min) ...
Yip Jennifer L Y - - 2010
AIMS: To determine if screening with an ultrasound A-scan and prophylactic treatment of primary angle closure (PAC) with laser peripheral iridotomy (LPI) can reduce the incidence of primary angle closure glaucoma (PACG) in Mongolia. METHODS: A single-masked randomised controlled trial was initiated in 1999. 4725 volunteer Mongolian participants ≥ 50 ...
Russell H C - - 2010
The use of topical mitomycin C (MMC) has gained popularity in the management of ocular surface neoplasia. The aim of this study is to determine outcomes and complications following such treatment. This study is a retrospective review of patients treated with topical MMC for ocular surface neoplasia, including primary acquired ...
Khakshoor Hamid - - 2010
To evaluate and compare the recurrence rates and complications between 2 therapeutic methods for primary pterygium: subconjunctival injection of mitomycin C (MMC) 1 month before bare scleral excision and conjunctival rotational flap with intraoperative MMC use. Prospective, interventional, randomized clinical trial. setting: Institutional clinical trial in a tertiary, specialty eye ...
Sugimoto Yosuke - - 2010
We aimed to investigate the effects of a single 1-mg injection of intravitreal bevacizumab on iris vessels in neovascular glaucoma (NVG) patients. Twenty-two surgically resected irises from glaucoma patients were obtained during trabeculectomy. Eight were from patients with NVG who received a 1-mg injection of intravitreal bevacizumab (IVB) before glaucoma ...
Gugleta Konstantin - - 2010
BACKGROUND: Dorzolamide and brinzolamide are topical carbonic anhydrase inhibitors (CAI) indicated for patients with glaucoma and ocular hypertension. SCOPE: An evidence-based review of clinical trials of dorzolamide and brinzolamide was undertaken to determine an effect of these medications on visual function (primarily visual field) in open-angle glaucoma and ocular hypertension. ...
Zhong Yisheng - - 2010
To investigate the effect of trabeculectomy in the management of glaucomatocyclitic crisis with uncontrolled intraocular pressures (IOPs) and visual field defects. Trabeculectomy was performed in 8 patients (2 males and 6 females) who had unilateral glaucomatocyclitic crisis with uncontrolled intraocular pressure (IOP) and visual field defects. After the surgeries the ...
Woodward Julie A - - 2010
To evaluate a bimatoprost gel for enhancing eyelash growth, adverse effects, and change in intraocular pressure (IOP). Prospective, double-masked, randomized controlled study. Fifty-two patients without ocular disease were assigned a control or bimatoprost 0.03% gel to apply to the eyelid margin once a day. The adjusted mean change in eyelash ...
Lee Paul P - - 2010
PURPOSE: To assess the degree of consensus among glaucoma experts on the measurement, characterization, and potential implications of intraocular pressure (IOP) and its fluctuation for glaucoma treatment. METHODS: A multinational panel of 9 glaucoma experts used a modified Delphi process to rate the level of agreement with 72 statements characterizing ...
Whitson Jess T - - 2010
PURPOSE: To compare the ocular surface tolerability of latanoprost 0.005% preserved with 0.02% benzalkonium chloride (BAK), bimatoprost 0.03% preserved with 0.005% BAK, and travoprost 0.004% preserved with the proprietary preservative system sofZia in patients previously treated with latanoprost. METHODS: This randomized, multicenter, investigator-masked, parallel-group study enrolled patients with open-angle glaucoma ...
Ge Jian - - 2010
Travoprost has been widely used for the treatment of patients with open-angle glaucoma (OAG) or ocular hypertension (OH). The aim of this study was to evaluate the intraocular pressure (IOP) lowering efficacy of travoprost 0.004% monotherapy in patients previously treated with other topical hypotensive medications, and in previously untreated patients. ...
Massa G C - - 2010
To evaluate the influence of pupil dilation on retinal nerve fibre layer (RNFL) measurements with spectral domain optical coherence tomography (OCT). In total, 29 healthy individuals and 26 glaucoma patients underwent RNFL measurements with the Cirrus HD-OCT Model 4000 (Carl Zeiss Meditec Inc.) before and 30-40 min after pupil dilation ...
Koranyi Gabor - - 2012
Purpose:  To compare the 4-year outcome of primary pterygium excision using intraoperative mitomycin C (MMC) with suturing a free conjunctival autograft (CA). Methods:  A total of 115 eyes with nasal primary pterygium of 115 patients were included in the study. After randomization into two groups, the eyes were operated on ...
Vold Steven D - - 2010
To report the impact of prior laser trabeculoplasty on clinical outcomes of Trabectome (NeoMedix Corporation, Tustin, CA) surgery. This is a retrospective, non-comparative study of consecutive cases of Trabectome surgery with 36 months of follow-up. Main outcome measures were intraocular pressure (IOP), number of glaucoma medications, and the occurrence of ...
Sun Xia - - 2010
PURPOSE: To compare the efficacy and safety of laser peripheral iridotomy with or without laser peripheral iridoplasty in the treatment of eyes with synechial primary angle-closure or primary angle-closure glaucoma. DESIGN: Randomized, controlled clinical trial. METHODS: Consecutive patients older than 40 years with synechial primary angle-closure or primary angle closure ...
Goyal Saurabh - - 2010
PURPOSE: To investigate the effect of 180° versus 360° primary selective laser trabeculoplasty (SLT) on tonographic outflow facility and intraocular pressure (IOP). DESIGN: Prospective, single masked randomised clinical trial. PARTICIPANTS: Patients with untreated primary open angle glaucoma or ocular hypertension both with IOP > 21-35 mmHg. METHODS: 40 patients randomly ...
Shedden Arthur - - 2010
The aim of this study was to compare the efficacy and tolerability of preservative-free (PF) and preservative-containing (PC) formulations of the dorzolamide/timolol fixed combination (COSOPT™) in patients with elevated intraocular pressure (IOP). A parallel, randomized, double-masked study was conducted. After a 3-week run-in on timolol, patients with ocular hypertension, as ...
Pacella E - - 2010
AIMS: To evaluate the ocular hypotensive effects and tolerability of the once daily fixed combination latanoprost-timolol versus twice daily 0.50% timolol associated or not with once daily latanoprost in patients suffering from Primary Open-Angle Glaucoma (POAG). METHODS: We compared the effects of such a combination with those of 0.50% timolol ...
Hyman Leslie - - 2010
OBJECTIVES: To characterize intraocular pressure (IOP) changes during 6 years of follow-up among patients with early, newly diagnosed glaucoma randomized to no initial treatment in the Early Manifest Glaucoma Trial (control group) and to evaluate factors associated with IOP changes in this group. METHODS: Early Manifest Glaucoma Trial control patients, ...
Mowatt Lizette - - 2010
PURPOSE: To determine the outcome of patients with hyphema secondary to ocular contusion. METHOD: A retrospective review of the ophthalmic records of 44 consecutive patients with traumatic hyphema secondary to ocular trauma presenting to the Eye Clinic of the University Hospital of the West Indies between May 2004 and November ...
Ichhpujani Parul - - 2010
PURPOSE: To study the demographic and clinical profile of the types of primary angle closure patients presenting at a tertiary care center in North India. MATERIALS AND METHODS: Clinic records of patients diagnosed as primary angle closure were reviewed. International Society of Geographical and Epidemiological Ophthalmology (ISGEO) classification scheme was ...
Tamçelik Nevbahar - - 2010
BACKGROUND AND OBJECTIVE: To present and evaluate a novel surgical technique to prevent exposure of the Ahmed valve implant tube (New World Medical, Rancho Cucamonga, CA) through conjunctiva in congenital glaucoma called "combined short scleral tunnel technique with Tenon advancement and duplication." PATIENTS AND METHODS: Patients with failed previous congenital ...
Magacho Leopoldo - - 2010
PURPOSE: To compare the measurement of diurnal fluctuations in intraocular pressure (IOP) in the same day versus over different days in primary open-angle glaucoma. METHODS: Twenty-five eyes from 25 patients with primary open-angle glaucoma were submitted to a diurnal curve on the same day, 5 measurements, 2.5 hours apart, from ...
Knip Maria M - - 2012
Purpose:  To investigate how prophylactic anterior chamber paracentesis affects the intraocular pressure (IOP) after intravitreal pegaptanib injections. Methods:  In this prospective study, 41 eyes of 41 patients receiving intravitreal pegaptanib injections were randomly assigned either to receive anterior chamber paracentesis prior to the injection (Group A, 20 patients, n = 35 injections) ...
Rosentreter André - - 2010
BACKGROUND: There is little information available about surgical management after failed glaucoma drainage device (GDD) surgery. We present the outcome of capsule excision after failed GDD surgery compared to capsule excision with additional use of a biodegradable implant (Ologen, version 2) as a placeholder. METHODS: In an observational comparative case ...
Bazzazi N - - 2010
This study aimed at comparing the results of the Conjunctival Autograft Technique (CAG) and Minimally Invasive Pterygium Surgery (MIPS) in primary pterygium excisions. This was a prospective randomized clinical study performed during a one-year period (2009-2010). One hundred and twenty two patients with primary pterygium were randomized in 2 groups: ...
Bozkurt M K - - 2010
To evaluate the efficacy of topical mitomycin in providing the patency of the neochoanae in children undergoing transnasal endoscopic congenital choanal atresia (CA) repair. A retrospective analysis of surgical results in CA patients who were treated in Selcuk University, Meram Medical Faculty, Department of Otolaryngology between November 2002 and November ...
Breusegem Christophe - - 2010
PURPOSE: To investigate the benefit of preoperative treatment with either topical nonsteroidal anti-inflammatory drug (NSAID) or steroid in terms of clinical outcomes following trabeculectomy. DESIGN: Prospective, randomized placebo-controlled trial. PARTICIPANTS: Sixty-one patients. METHODS: Between July 2005 and October 2007, 61 consecutive medically uncontrolled glaucoma patients scheduled for first-time trabeculectomy were ...
Hermann Manuel Marcel - - 2010
The success of many medical treatments is built on compliance. Electronic monitoring is the most accurate tool to quantify compliance by measuring adherence. In order to assess the efficiency of a recently introduced miniature monitoring device for eye drop application, we evaluated adherence in ophthalmic patients undergoing post-operative short-term topical ...
Tan Anna M - - 2010
BACKGROUND: Transscleral diode laser cyclophotocoagulation (TSCPC) is an established method of treatment for refractory glaucoma, but is associated with significant complications. This study evaluates the efficacy and safety of a new form of TSCPC using micropulse diode laser and trans-pars plana treatment with a novel contact probe. METHODS: Prospective interventional ...
Stewart William C - - 2010
PURPOSE: To compare the change in 24-h fluctuation of the intraocular pressure (IOP) from various medical therapies in patients with ocular hypertension, primary open-angle (POAG), or exfoliative glaucoma (XFG). METHODS: A meta-analysis of published studies that were controlled, prospective, and comparative trials. Based on study requirements for an objective fluctuation ...
Aponte Elisabeth P - - 2010
To describe the incidence and clinical characteristics of childhood glaucoma in a defined population of the United States. The medical records of all pediatric patients younger than 20 years living in Olmstead County, Minnesota, from January 1, 1965, through December 31, 2004, who met diagnostic criteria for glaucoma or glaucoma ...
Ang Ghee Soon - - 2010
PURPOSE: To determine the effect of cataract extraction on the glaucoma progression index (GPI) in glaucoma patients with coexisting cataract. PATIENTS AND METHODS: This is a retrospective noncomparative study. Consecutive eligible patients with glaucoma who underwent phacoemulsification alone or in combination with augmented trabeculectomy were included. All patients had Swedish ...
Kashkouli Mohsen Bahmani - - 2010
PURPOSE: To compare the anatomical pattern of lacrimal drainage system obstruction (LDSO) associated with topical anti-glaucoma medications (AGM) with a control group. METHODS: In a cross-sectional controlled study, case group included patients on topical anti-glaucoma medications and control group included patients with no history of glaucoma, free of ocular disease, ...
Katz L Jay - - 2010
PURPOSE: To evaluate the intraocular pressure (IOP)-lowering efficacy and safety of ophthalmic formulations of bimatoprost 0.01% and 0.0125% compared with bimatoprost 0.03%. DESIGN: Prospective, randomized, double-masked, multicenter clinical trial. METHODS: Patients with glaucoma or ocular hypertension were randomized to receive once-daily bimatoprost 0.01% (n = 186), bimatoprost 0.0125% (n = ...
Zhou Alysia W AW Schulich School of Medicine and Dentistry, University of Western - - 2010
To determine whether preoperative anterior chamber angle width, captured by anterior segment optical coherence tomography (AS-OCT), can be a predictor of intraocular pressure (IOP) change following cataract surgery. Prospective comparative observational study. Fifty-three eyes of 53 patients awaiting cataract surgery were included. Measurement of anterior chamber angle width and IOP ...
Sohn Sae Woon - - 2010
PURPOSE: To evaluate the influence of the extent of myopia on the progression rate of normal-tension glaucoma (NTG). DESIGN: Retrospective, observational case series. METHODS: One hundred forty-three eyes of 143 patients with NTG who were treated from 1994 through 2006 and followed up with standard automated perimetry were evaluated in ...
Fernández-Barrientos Yolanda - - 2010
PURPOSE. To evaluate the changes in aqueous humor dynamics and the efficacy and safety of the iStent (Glaukos Corp., Laguna Hills, CA), in combination with cataract surgery. METHODS. This investigation was a prospective, randomized, clinical study in patients with open-angle glaucoma or ocular hypertension who were undergoing cataract surgery. Aqueous ...
Matzkin Haim - - 2012
Preoperative planning (PP) and intraoperative planning (IoP) are established (125)I-brachytherapy techniques for the treatment of localized prostate cancer. We prospectively compared the effects of each method on reducing PSA levels. One hundred eighty patients treated with brachytherapy as monotherapy without neoadjuvant androgen deprivation therapy or external beam radiation using PP ...
Kobelt Gisela - - 2010
To investigate long-term resource consumption and clinical outcome of patients with early primary open-angle glaucoma or ocular hypertension treated with prostaglandins in clinical practice in France. Thirty-four geographically spread specialized hospitals and private practices enrolled consecutive patients receiving, for the first time, a prostaglandin, alone or in combination. The study ...
Nassiri Nader - - 2010
PURPOSE: To compare 1-site and 2-site phacotrabeculectomies with regard to visual acuity, intraocular pressure (IOP) control, antiglaucoma medication requirements, and postoperative complications. METHODS: In a randomized controlled trial, 169 eyes with coexisting visually significant cataract and glaucoma were randomly allocated into 2 groups: eyes that had a trabeculectomy in a ...
Orme M - - 2010
OBJECTIVES: Primary open-angle glaucoma (POAG) is a chronic condition characterised by optic neuropathy and vision loss. Elevated intraocular pressure (IOP) can damage the optic nerve and is a risk factor for glaucoma, thus treatment usually comprises topical hypotensives. This analysis aims to address methodological issues associated with the synthesis of ...
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