Search Results
Results 301 - 350 of 1747
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Ad N - - 2012
AIM: Elderly patients with atrial fibrillation (AF) present a special challenge. Despite the documented advantage in ablating AF, the addition of the procedure may add complexity and potentially impact patient outcome. This study explored the impact of the Cox-Maze III/IV procedure on elderly patients experiencing AF who present for cardiac ...
Liao Chun-Hou - - 2012
PURPOSE: Intravesical injection of onabotulinumtoxin A (BoNT-A) is effective for idiopathic detrusor overactivity (IDO) refractory to antimuscarinics. However, safety is a major concern, especially for the elderly. We investigate the efficacy and safety of intravesical BoNT-A injections for refractory IDO in frail elderly. MATERIALS AND METHODS: From 2004-2009, 166 patients ...
Chen Jingjun - - 2013
Laparoscopic cholecystectomy is performed with increasing frequency in aging populations. However, in elderly patients, cognitive dysfunction following surgery may impair the outcome of surgical procedures. Dexmedetomidine (DEX) has been demonstrated to have a neuroprotectve effect in animal experiments. However, it is unclear whether DEX also has a neuroprotective effect in ...
Yamamoto Takanori - - 2012
In this previously reported multicenter study, teriparatide 20 μg/day was administered to elderly Japanese subjects (93 % female; median age 70 years) with osteoporosis and at high risk of fracture during a 12-month, randomized, double-blind, placebo-controlled period, which was followed by a 12 month treatment period in which all subjects received open-label teriparatide. Subjects ...
Hassanzadeh Hamid - - 2012
ABSTRACT: Study Design. Retrospective review.Objective. To report and analyze the perioperative complications, radiographic results, and functional outcomes in elderly patients undergoing pedicle subtraction osteotomy (PSO) and/or vertebral column resection (VCR) procedures for spinal deformity correction.Summary of Background Data. To our knowledge, no studies have focused on 3-column osteotomies in the ...
Markar Sheraz R - - 2012
PURPOSE: To assess short and long-term outcomes for patients aged ≥80 years undergoing esophagectomy for malignancy. METHODS: All patients undergoing esophagectomy for cancer between 1991 and 2011 had information prospectively entered into a database; patients were divided into elderly (≥80 years) and younger (<80 years) groups. RESULTS: Of the 500 patients included, 32 ...
Ellwood Amanda D AD Department of Medicine, Division of Nephrology, Western University, London, Ontario, - - 2013
The number of elderly patients and those with higher estimated GFR (eGFR) initiating dialysis have recently increased. This study sought to determine rates of withdrawal from dialysis and variables associated with withdrawal. Canadian Organ Replacement Registry data were used to examine withdrawal rate and identify variables associated with withdrawal among ...
Kantarjian Hagop H The University of Texas MD Anderson Cancer Center, Houston, TX, USA. - - 2012
Available treatments for acute myeloid leukaemia (AML) have limited durable activity and unsatisfactory safety profiles in most elderly patients. We assessed the efficacy and toxicity of sapacitabine, a novel oral cytosine nucleoside analogue, in elderly patients with AML. In this randomised, phase 2 study, we recruited patients with AML who ...
Kadoi Yuji - - 2012
PURPOSE: This study was conducted to (1) compare the recovery times from rocuronium-induced muscle relaxation after reversal with sugammadex between young and elderly patients undergoing electroconvulsive therapy (ECT), and (2) to examine the existence of a correlation between cardiac index and reversibility of rocuronium-induced neuromuscular block with sugammadex after ECT. ...
Entezariasl Masood - - 2012
With consideration the daily increased development of outpatient surgeries and high rate of these surgeries in elderly patients, rapid and safe recovery of patients is necessary. In this clinical trial study, recovery time and nausea and vomiting after the use of two rapid-onset narcotics, Alfentanil and Remifentanil, in elderly patients ...
Biondi Alberto - - 2012
BACKGROUND: The aim of this study was to evaluate the possibility of a different path to achieve curative surgery in patients older than age 70 years and affected by resectable gastric cancer. STUDY DESIGN: This is a multicentric retrospective study based on an analysis of 1,465 patients with gastric adenocarcinoma ...
Chan Matthew T V - - 2012
BACKGROUND:: Previous clinical trials and animal experiments have suggested that long-lasting neurotoxicity of general anesthetics may lead to postoperative cognitive dysfunction (POCD). Brain function monitoring such as the bispectral index (BIS) facilitates anesthetic titration and has been shown to reduce anesthetic exposure. In a randomized controlled trial, we tested the ...
Puls Miriam - - 2012
Aims: Transcatheter aortic valve implantation (TAVI) has recently developed into an accepted alternative to conventional surgery in high-risk patients. According to current data, post-TAVI prosthetic valve endocarditis (PVE) seems to occur very rarely. Methods and results: We followed the first 180 consecutive patients who underwent TAVI at our institution to ...
Schoenenberger Andreas W - - 2012
AimsThis study aimed to assess functional course in elderly patients undergoing transcatheter aortic valve implantation (TAVI) and to find predictors of functional decline.Methods and resultsIn this prospective cohort, functional course was assessed in patients ≥70 years using basic activities of daily living (BADL) before and 6 months after TAVI. Baseline ...
Kiran Ravi P - - 2012
OBJECTIVE:: The ability to accurately predict postoperative mortality is expected to improve preoperative decisions for elderly patients considered for colorectal surgery. METHODS:: Patients undergoing colorectal surgery were identified from the National Surgical Quality Improvement Program database (2005-2007) and stratified as elderly (>70 years) and nonelderly (<70 years). Univariate analysis of ...
Lundin Karin - - 2012
OBJECTIVES: To analyse complications and outcome of cochlear implant (CI) treatment in seniors receiving CIs during a 10-year period. METHODS: A total of 28 patients, 79 years or older (mean age 81.6 years), were evaluated and compared with a younger group of 76 patients, 20-60 years old (mean age 48.9 ...
Turrini O - - 2012
AIM: To determine the benefit of surgery for resectable pancreatic adenocarcinomas (PAs) in elderly patients. METHODS: From 2004 to 2009, 932 patients with resectable PAs underwent pancreatectomies without neoadjuvant treatment in 37 institutions. The patients were divided into three groups according to age: <70 years (control group; n = 580); 70-79 years ...
Erdogan Mehmet Ali - - 2012
PURPOSE: The objective of this study was to compare the effects of ketamine-propofol mixture (ketofol) and propofol on ProSeal laryngeal mask airway (PLMA) insertion conditions and hemodynamics in elderly patients. METHODS: Eighty elderly patients, American Society of Anesthesiologists (ASA) physical status I and II, were randomly divided into two groups ...
Martinez-Garcia Miguel-Angel - - 2012
RATIONALE: Obstructive sleep apnoea (OSA) is a risk factor for cardiovascular death in middle-age subjects, but it is not known whether it is also a risk factor in the elderly. OBJECTIVES: To investigate whether OSA is a risk factor for cardiovascular death and assess whether continuous positive airway pressure (CPAP) ...
Angioli Roberto - - 2012
INTRODUCTION AND HYPOTHESIS: Urgency urinary incontinence (UUI) frequently occurs in elderly. International guidelines recommend pharmacological therapy as first-line treatment, but elderly do not respond in many cases. The purpose of this study was to report cure rates, quality of life, and feasibility of sacral neurostimulation (SNS) as an alternative option ...
Zhou Hu - - 2012
Immune thrombocytopenia (ITP), often diagnosed in the elderly, is a hematologic disorder induced by autoimmune mechanism. In this retrospective study, we evaluated the clinical features, the risk of bleeding, and the response to treatment in 525 elderly ITP patients (age ≥60 years) diagnosed at our center from 1980 to 2009. There ...
Gupta Bhanu P - - 2012
Patterns of clinical symptoms and outcomes of perioperative myocardial infarction (PMI) in elderly patients after hip fracture repair surgery are not well defined. A retrospective 1:2 case-control study in a cohort of 1212 elderly patients undergoing hip fracture surgery from 1988 to 2002 in Olmsted County, Minnesota. The mean age ...
Noh Heil - - 2012
Objectives:  To evaluate the vascularization process of the grafted fascia or perichondrium in active and inactive chronic mucosal otitis media. Design:  Prospective study. Setting:  University-based, secondary referral hospital. Participants:  Two-hundred thirty two patients who underwent type 1 tympanoplasty or myringoplasty by one experienced surgeon. Main outcome measures:  After postoperative days ...
Luger Thomas J - - 2012
The aim of our study was to investigate the clinical relevance of preoperative acute pain management and cardiovascular stability by ultrasound-guided continuous 3-in-1 nerve block in very elderly patients with hip fracture when compared to epidural anesthesia (PDA). To study the analgesic effect, we enrolled 37 very elderly patients with ...
Pesić Ivan - - 2012
Incarcerated inguinal hernias surgical treatment represents one of the most frequent surgical treatments in elderly patients. The percentage of incarcerated inguinal hernias urgent surgical treatments is growing exponentially with the age in patients over 50. The aim of the study was to investigate some of the factors that may have ...
Strasser Nicholas L - - 2012
Ankle arthrodesis has been the gold standard operative treatment for ankle arthritis refractory to nonoperative treatment. Although multiple studies have evaluated the outcomes after ankle fusion, none has focused on outcomes in elderly patients. The purpose of this study was to evaluate outcomes of ankle fusion in patients over the ...
Krenk Lene - - 2012
Postoperative delirium (PD) and postoperative cognitive dysfunction (POCD) are two separate syndromes of cognitive decline after major surgery, especially in the elderly. Pathogenesis is multifactorial with some common risk factors, and to reduce the risk, a multimodal approach is necessary. The fast-track methodology is becoming a well-established perioperative care regime ...
Asleh Karama - - 2012
The Norton scoring system is used by nurses to evaluate pressure ulcer risk. The authors have previously shown that low admission Norton scale scores (ANSS) are associated with postoperative complications other than pressure ulcers following hip fracture and spine fracture surgery in elderly patients. The purpose of this retrospective, cross-sectional ...
Fanfani F - - 2012
BACKGROUND: To examine the surgical treatment and clinical outcome of elderly and very elderly advanced epithelial ovarian cancer patients. METHODS: We retrospectively analyzed FIGO stage IIIC-IV ovarian cancer patients, divided in elderly (Group A, >65 and <75 years) and very elderly patients (Group B, ≥75 years) treated by primary debulking ...
Oliveira-Cunha Melissa M The HPB and Transplant Unit, St James University Hospital, Leeds, - - 2013
By 2033, the number of people aged 85 years and over in the UK is projected to double, accounting for 5% of the total population. It is important to understand the surgical outcome after a pancreatic resection in the elderly to assist decision making. Over a 9-year period (from January ...
Blom R L G M - - 2012
Esophagectomy in elderly esophageal carcinoma patients is correlated with a high morbidity and even mortality. Studies on neoadjuvant chemoradiotherapy (NT) in elderly patients are scarce. The aim of this study was to evaluate the effect of advanced age in combination with NT in esophageal carcinoma patients who underwent an esophagectomy. ...
Tepeler Abdulkadir - - 2012
Objectives: The treatment of symptomatic lower pole (LP) calculi poses a challenge due to lower clearance rates. Herein we present our experience with microperc in the treatment of LP renal calculi. Patients and Methods: We retrospectively evaluated the symptomatic patients with LP renal calculi who underwent microperc between August 2011 ...
Apostolopoulos A P - - 2012
There are several studies reporting the incidence of suprapatellar, medial, and lateral plicae, but there is very limited information regarding the incidence of the infrapatellar plica. The purpose of our study was to record the incidence of infrapatellar plicae in the elderly Welsh population suffering from knee osteoarthritis. A prospective ...
Kim Young-Hoo - - 2012
We are aware of no information about the mid-term performance of the high-flexion total knee arthroplasty, although early results have been reported. The purpose of this study was to evaluate the mid-term results of high-flexion and conventional knee prostheses. We prospectively compared the results of 100 patients with osteoarthritis who ...
Yang Changyong - - 2012
The study aim was to investigate the influence of 'urgent' status on short and long-term mortality and morbidity in a consecutive series of octogenarian patients who underwent aortic valve replacement (AVR). Between January 2005 and March 2009, data were extracted for 141 consecutive patients aged over 80 years who underwent ...
Stendell Line - - 2012
The incidence of post dural puncture headache (PDPH) after lumbar puncture (LP) can be reduced from 36% to 0-9% by use of an atraumatic needle size 24 gauge (G)/0.56 mm rather than a traumatic needle size 22 G/0.7 mm. The evidence supporting some of the prophylactic and therapeutically treatments of ...
Kim Sang-Chul - - 2012
Background: Elderly patients with major ischemic strokes may remain severely disabled or dead. However, efficacy and safety of thrombolysis in this have not been fully explored. Materials and Methods: Data from the case records of patients aged >80 years with acute ischemic stroke with admission National Institute of Health Stroke ...
Kim Hyeong Il - - 2012
The prevalence of hepatitis C virus (HCV) infections in elderly patients has been increasing in a number of countries. A few reports concerning pegylated interferon-α (PEG-IFN-α)-based combination treatment in elderly chronic hepatitis C (CHC) patients have been published, with slightly different treatment outcomes. We investigated the treatment response and safety ...
Li Yong Y Critical Care Medicine Unit, the Affiliated People's Hospital of Jiangsu University, Dian Li Road NO.8, Zhen Jiang City, Jiang Su Province 212002 - - 2013
Serum procalcitonin (PCT) levels may have predictive value in the prognosis of postoperative sepsis in elderly patients who have undergone colorectal surgery for colorectal cancer in intensive care units (ICUs). A prospective study involving 90 critically ill patients who underwent colorectal surgery for colorectal cancer in ICUs was performed. Twenty-eight ...
Gopinath Ramachandran R Department of Anaesthesia and Intensive Care, NIMS, Hyderabad, - - 2013
The aim of this study was to evaluate the immunomodulatory effects of supplementing intravenous omega-3 fatty acids in fish oil (IVFO) in elderly patients undergoing hip surgery. This was a single centre, randomized, controlled, comparative, phase IV study in elderly patients undergoing hip surgery. The subjects, within the age range ...
Bloch Orin - - 2012
Ventriculoperitoneal shunt placement is the standard of care for idiopathic normal pressure hydrocephalus (iNPH). Studies have reported shunt complication rates up to 38%, with subdural hemorrhage rates as high as 10%. Lumboperitoneal (LP) shunts with horizontal-vertical valves (HVV) are an alternative for cerebrospinal fluid (CSF) diversion that avoids direct cerebral ...
Coin Alessandra - - 2012
The aim of this study was to assess, in a natural setting, the development of cognitive, behavioral and functional performance of elderly dementia patients treated with cholinesterase inhibitors (ChEIs) during a 21-month follow-up. Another aim was to compare patterns of clinical changes in relation to patients' level of cognitive impairment ...
Yu Jae Won - - 2012
Malignant middle cerebral artery (MCA) infarction occurs in 10% of all ischemic strokes and these severe strokes are associated with high mortality rates. Recent clinical trials demonstrated that early decompressive craniectomy reduce mortality rates and improves functional outcomes in healthy young patients (less than 61 years of age) with a ...
Kardys Isabella - - 2012
BACKGROUND: This prospective study investigated the association between preprocedural biomarker levels and incident major adverse cardiac events (MACE) in complex patients undergoing percutaneous coronary intervention (PCI) with sirolimus-eluting stenting. HYPOTHESIS: Lipoprotein(a) (Lp[a]), interleukin-10 (IL-10), and high-sensitivity C-reactive protein (CRP) have long-term prognostic value in patients undergoing PCI. METHODS: Between April ...
Taylor Fraser - - 2012
Controversy exists regarding the use of cement for hemiarthroplasty to treat a displaced subcapital femoral neck fracture in elderly patients. The primary hypothesis of this study was that use of cement would provide better visual analog pain scores following this procedure in an elderly patient population. Elderly patients (at least ...
Domon Kaoru - - 2012
Aim:  In this study, the aim was to determine the demographic characteristics of elderly patients with gastroduodenal ulcer who had undergone endoscopic hemostasis by comparing them with younger patients. Methods:  A total of 353 patients with Forrest class I-IIa hemorrhagic gastroduodenal ulcer who underwent endoscopic hemostasis at our hospital between ...
Ho Sgy - - 2012
Abstract Background: The risk of post-inflammatory hyperpigmentation (PIH) is increased during freckles and lentigines treatment in Asians. Objective: To determine the effectiveness and safety of using 595nm long pulsed dye laser (LPDL), 755nm LP Alexandrite laser, 532 nm QS Nd:YAG laser and 532 nm LP potassium-titanyl-phosphate (KTP) laser for the ...
van der Toorn Fred - - 2012
OBJECTIVE: To report clinical outcomes for laparoscopic pyeloplasty (LP) in children compared with open pyeloplasty (OP) and literature findings. PATIENTS AND METHODS: In a prospective study, the outcomes of 57 consecutive transperitoneal LP in children from the age of 3 years were analyzed and compared with a matched historic control ...
Weberová D - - 2012
Pulmonary embolism (PE) is after myocardial infarction and cerebrovascular events the third most frequent cardiovascular cause of death. Simultaneously it belongs to at least often correctly diagnosed cardiovascular diseases. The The retrospective analysis of the database of inpatients with the target assess the clinical course of PE according to prevalence, ...
Văcăroiu Ileana Adela - - 2012
The prevalence of treated patients with end-stage renal disease (ESRD) has considerably increased in the last decade mainly in the elderly age groups. The type of optimal mode of dialysis therapy in elderly is difficult to establish and most studies comparing hemodialysis and peritoneal dialysis in elderly failed to demonstrate ...
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