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Park Tae Young TY Division of Gastroenterology, Chung-Ang University College of Medicine, Seoul, - - 2014
Endoscopic retrograde cholangiopancreatography (ERCP) has been increasingly performed in the elderly patients, yet little is known concerning objective criteria of safety. This study aimed to determine the potential predictors for the procedure-related outcomes. 281 patients older than 70 years who were indicated for ERCP [group A (n=195), 70-79 years of ...
Ueda Takashi T Department of Dermatology, Kitasato University School of Medicine, Sagamihara, - - 2014
A 66-year-old woman with a history of deep vein thrombosis (DVT) presented with an irregularly shaped leg ulcer surrounded by pigmentation on the left lower limb. In addition, the circumference of her left thigh had gradually increased. The ulcer did not respond to topical treatment and enlarged, therefore, she visited ...
Kanda Mitsuro M From the Department of Gastroenterological Surgery (Surgery II), Nagoya University Graduate School of Medicine, Nagoya, - - 2014
We aimed to evaluate the feasibility and clinical benefit of pancreatoduodenectomy (PD) with portal vein resection (PVR) in elderly patients. This retrospective study enrolled 272 consecutive patients with pancreatic ductal adenocarcinoma who underwent PD between 2000 and 2012. The patients were categorized into 4 groups: elderly (≥70 years) and younger ...
Horiuchi Tetsuyoshi T Department of Neurosurgery, Shinshu University School of Medicine, 3-1-1 Asahi, Matsumoto 390-8621, Japan. Electronic address: - - 2014
This study investigated the outcome of clipping surgery for ruptured aneurysms in patients older than 80years of age. From 1988 to 2011 data were retrospectively reviewed, and 196 patients treated with clipping obliteration for aneurysmal subarachnoid hemorrhage were identified. Patients were divided into two age groups of 80-84 and ⩾85years ...
Parra-Membrives Pablo P *Department of Surgery, University of Seville †Hepato-bilio-pancreatic Surgery Unit, General and Digestive Surgery Department, Valme University Hospital, Sevilla, - - 2014
Although surgery is frequently not the first treatment option in elderly patients diagnosed with common bile duct stones (CBDS) because of the fear of high morbidity and mortality rates, there are few data about the safety and efficacy of laparoscopic common bile duct exploration (LCBDE) in the elderly. From February ...
Wenaweser Peter P Department of Cardiology and Department of Cardiovascular Surgery, Swiss Cardiovascular Centre, Bern University Hospital, Bern, - - 2014
Aims: To evaluate short-term clinical outcomes following transcatheter aortic valve implantation (TAVI) using CE-mark approved devices in Switzerland. Methods and results: The Swiss TAVI registry is a national, prospective, multicentre, monitored cohort study evaluating clinical outcomes in consecutive patients undergoing TAVI at cardiovascular centres in Switzerland. From February 2011 to ...
Lin G-X GX Department of Anesthesiology, The Third Xiangya Hospital of Central South University, Changsha, - - 2014
Accumulating evidence has indicated that inflammation may act as a potential mechanism underlying post-operative cognitive dysfunction (POCD). High-mobility group box 1 (HMGB1), as a known late mediator of inflammation, is involved in the development of post-operative complications. Thus, we sought to determine the role of HMGB1 in reflecting POCD following ...
Wang Zhi-Hua ZH From the Department of Anesthesiology, Xijing Hospital, Fourth Military Medical University, Shaanxi, - - 2014
Delayed emergence from general anesthesia frequently occurs in elderly patients, but the reason is not clear. Orexin has been shown to be involved in arousal from general anesthesia. In this study, we examined plasma orexin-A levels in both elderly and young patients during the anesthesia arousal cycle. We recruited 41 ...
Agarwal Deepti D Department of Anaesthesiology and Critical Care, University College of Medical Sciences and Guru Teg Bahadur Hospital, Delhi, - - 2014
In elderly patients, use of adjuvant with small doses of local anesthetics is a preferred technique for spinal anesthesia for lower limb surgeries. This study tested the hypothesis that addition of small doses of clonidine augments the spinal block levels produced by hyperbaric bupivacaine in elderly without affecting the side-effects ...
Taramasso Maurizio M Cardiac Surgery Department, San Raffaele University Hospital, Milan, Italy. Electronic address: - - 2014
The study objective was to report the midterm outcomes of MitraClip implantation in inoperable or high-risk surgical candidates with degenerative mitral regurgitation. From October 2008, data of all high-risk or elderly patients with severe degenerative mitral regurgitation who underwent MitraClip implantation were prospectively collected. Forty-eight high-risk consecutive patients with severe ...
Komatsu Kazunori K Department of Cardiovascular Surgery, Shinshu University School of Medicine, Matsumoto, Nagano, - - 2014
Age is still considered a risk factor in the repair of acute type A aortic dissection. Instead of total arch replacement, we performed hemiarch or partial arch replacement with intimal tear exclusion to reduce death in elderly patients and evaluated early-term and midterm outcomes. From January 2004 to April 2012, ...
Starks Ian I Orthopaedic Department, Wrexham Maelor Hospital, Wrexham, - - 2014
Between August 2007 and May 2009, 2128 consecutive patients underwent either primary hip or knee joint replacement surgery at our institute on an enhanced recovery pathway. We aimed to investigate the potential benefits of this pathway in patients over the age of 85 years. Data extracted from Hospital Episode Statistics ...
Dalbeni A A Department of Medicine, University of Verona, Verona, Italy. Electronic address: - - 2014
Low plasma vitamin D levels have been associated with heart failure (HF). This research attempts to explain the role of vitamin D supplementation on myocardial function in elderly patients with HF. Twenty-three chronic HF patients were randomized in a small parallel group, double-blind, placebo-controlled trial. All patients, with a mean ...
Gulec Demet D Department of Anaesthesiology and Reanimation, Faculty of Medicine, Akdeniz University, Antalya, - - 2014
To compare two intrathecal anaesthetics, bupivacaine and levobupivacaine, for their effects on motor and sensory blockade and haemodynamics in patients aged ≥65 years undergoing transurethral resection of the prostate (TUR-P) or transurethral resection of the urinary bladder (TUR-M). Patients scheduled to undergo TUR-P or TUR-M were randomized to receive either ...
Doger C - - 2014
Introduction: The present study compared the effect of bupivacaine and bupivacaine + sufentanil on hemodynamic parameters and characteristics of spinal anesthesia in elderly patients undergoing transurethral resection of the prostate (TURP) under spinal anesthesia. Technical Considerations: The study included 40 American Society of Anesthesiologists (ASA) I-III patients scheduled to undergo ...
Stroink J J JJ Hart-long Centrum, Medisch Centrum Alkmaar, Postbus 501, 1800, AM, Alkmaar, the Netherlands, - - 2014
There are two treatment strategies for medication-resistant atrial fibrillation (AF): rhythm control or rate control. It has been suggested that rate control is a valid strategy in well-tolerated AF because it does not result in increased mortality. We aimed to investigate the 1-year outcome of rhythm control in an elderly ...
He Peiyuan P Department of Cardiology, Cardiovascular Institute and Fuwai Hospital, National Center for Cardiovascular Diseases China, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, 100037, - - 2014
Transradial approach (TRA) percutaneous coronary intervention (PCI) has been wildly applied among unselected patients. However, only very few small studies have compared the outcomes between TRA and transfemoral approach (TFA) in elderly patients. We aimed to evaluate the efficacy and safety between TRA and TFA in elderly patients by a ...
Wang Sirui S From the *Norman Bethune College of Medicine, Jilin University; †Changchun University of Traditional Chinese Medicine; ‡Department of Neurosurgery, First Affiliated Hospital of Jilin University; and §Department of the Human Anatomy, Norman Bethune College of Medicine, Jilin University, Changchun, - - 2014
Our study aims to illustrate the precise location of sellar floor of patients with different saddle forms for pituitary surgery through unilateral endonasal transsphenoidal approach, by measuring 2 angles and 2 distances. One hundred thirty-three (74 men and 59 women) participated in this study anonymously. Results are as follows: the ...
Mori Shozo S Department of Gastroenterological Surgery, Dokkyo Medical University, Tochigi, - - 2014
Abstract The outcome of liver resection (LR) for elderly hepatocellular carcinoma (HCC) patients with portal hypertension (PHT) who may be excluded as liver transplantation candidates has not been fully evaluated. One hundred ninety-five patients who underwent initial curative LR for HCC with PHT were divided into 2 groups: age <70 ...
Berman-Rosenzweig Erika E Department of Medicine, Columbia School of Medicine, New York, New York, - - 2014
There are limited data on the management of pulmonary arterial hypertension (PAH) in the elderly; therefore, this analysis compared the safety and efficacy of tadalafil between patients ≥65 and <65 years old. This was a post hoc analysis of the randomized, double-blind, placebo-controlled phase 3 Pulmonary Arterial Hypertension and Response ...
Fukunaga Naoto - - 2014
Very few data exist regarding the clinical outcome of redo valvular surgery in patients aged > 75 years. A retrospective analysis was conducted of 42 consecutive patients (mean age 78.3 years) who had undergone redo valvular surgery between January 1991 and December 2010, and who had been followed up for ...
Huang Xiao X Department of Orthopaedics, West China Hospital, Sichuan University, 37# Guoxue Rd, Chengdu, 610041, Sichuan, - - 2014
This meta-analysis was conducted to investigate whether helical blade implant system had advantages in terms of cut-out rate when compared to screw implant system for trochanteric fractures of elderly population. The databases of MEDLINE, Cochrane Library and OVID were searched from inception to September 2013, and all randomized controlled trials ...
Fukata Shinji S Department of Surgery, National Center for Geriatrics and Gerontology, Obu, Japan, - - 2014
Postoperative delirium is the most common postoperative complication in the elderly. The purpose of this study was to evaluate the safety and effectiveness of the preventive administration of low-dose haloperidol on the development of postoperative delirium after abdominal or orthopedic surgery in elderly patients. A total of 119 patients aged ...
Machino Takeshi T Cardiovascular Division, Institute of Clinical Medicine, Graduate School of Comprehensive Human Sciences, University of - - 2014
Background: Linear ablation of atrial flutter usually targets a 6 o'clock position on the cavotricuspid isthmus on left anterior oblique view, but the difficulty of the ablation often requires a variation in successful ablation line position from 5 to 7 o'clock. Methods and Results: This study included 94 patients without structural heart ...
Bito Seiji S Division of Clinical Epidemiology, NHO Tokyo Medical Center, Tokyo, - - 2014
Background: The effects of various artificial nutrition methods on the long-term outcomes of elderly patients are still not well known. We aimed to compare the long-term survival of the elderly newly administered with parenteral nutrition (PN) or enteral nutrition. Materials and Methods: This multicenter, prospective, observational cohort study was conducted ...
Kanda Eiichiro E Department of Nephrology, Tokyo Kyosai Hospital, Tokyo, - - 2014
Background/Aims: Non-volatile acid is produced by metabolism of organic sulfur in dietary protein, and promotes kidney damage. We investigated the role of dietary acid load, in terms of net endogenous acid production (NEAP), in chronic kidney disease (CKD) progression. Methods: 217 CKD patients on low-protein diet with a normal serum ...
Round Elizabeth M EM Merck & Co., Inc., Whitehouse Station, NJ, USA, - - 2014
The aim of this study was to evaluate the safety and tolerability of sitagliptin 100 mg/day in elderly patients with type 2 diabetes. A post hoc pooled analysis of 25 randomized, double-blind, parallel group clinical studies with results available as of 1 December 2011. Multicenter, international clinical trials. Patients with type ...
Smith Cardinale B CB *Tisch Cancer Institute, † Department of Medicine, Division of General Internal Medicine, Mount Sinai School of Medicine, NY, New York; ‡ Department of Medicine, Division of Hematology/Oncology, Columbia University, NY, New York; §Department of Epidemiology, Mailman School of Public Health, Columbia University, NY, New York; and Departments of ‖Preventive Medicine and ¶ Medicine, Division of Pulmonary and Critical Care Medicine, Mount Sinai School of Medicine, NY, New - - 2014
Video-assisted thorcacic surgery (VATS) is considered an alternative to open lobectomy for the treatment of non-small-cell lung cancer (NSCLC). Limited data are available, however, regarding the equivalence of open versus VATS segmental resections, particularly among elderly patients. From the Surveillance, Epidemiology, and End Results-Medicare database we identified 577 stage I ...
Sündermann Simon H SH Division of Cardiovascular Surgery, University Hospital Zurich, Zurich, - - 2014
Assessment of perioperative risk of elderly patients in cardiac surgery is difficult, and most of the common risk scores show over- or underestimation. Two frailty scores, the comprehensive assessment of frailty (CAF) score and the Frailty predicts death One yeaR after CArdiac Surgery Test (FORECAST), were developed as additional tools ...
Chan Yiu Che YC Division of Vascular and Endovascular Surgery, Department of Surgery, University of Hong Kong Medical Center, Queen Mary Hospital, Hong Kong. Electronic address: - - 2014
The Supera helical interwoven nitinol stent has enhanced flexibility in counteracting fractures when placed in the femoropopliteal arteries and may improve patency. The aim of this study is to assess the early results of the Supera stent in symptomatic patients with femoropopliteal atherosclerotic lesions. From October 2011 to April 2013, ...
Sternberg C N CN San Camillo and Forlanini Hospitals, Rome, - - 2014
The randomized, double-blind phase III AFFIRM trial demonstrated that enzalutamide, an oral androgen receptor inhibitor, significantly prolonged overall survival (OS) [median 18.4 versus 13.6 months (hazard ratio, HR) 0.63 (95% confidence interval, CI, 0.53-0.75); P < 0.001] compared with placebo in patients with metastatic castration-resistant prostate cancer who received prior ...
Gaur Puja P Division of Cardiac Surgery, Brigham and Women's Hospital, Harvard Medical School, Boston, - - 2014
To compare the short-term and long-term outcomes of mitral valve repair (MVP) versus mitral valve replacement (MVR) in elderly patients. All patients, age 70 years or greater, with mitral regurgitation who underwent MVP or MVR with or without coronary artery bypass graft (CABG), tricuspid valve surgery, or a maze procedure ...
Buckinx F F Department of Public Health, Epidemiology and Health Economics, University of Liège, Liège, Belgium, - - 2014
We have previously shown that short sessions of whole body vibration (WBV) were not able to significantly improve fall risk among nursing home residents but some trends towards an improvement of motor capacity were observed. The objective of the present study was to evaluate the impact of 6-month training by ...
Wang Wan-Li WL aDepartment of Hepatobiliary Surgery, First Affiliated Hospital, School of Medicine bInstitute of Advanced Surgical Technology and Engineering, Xi'an Jiaotong University, Xi'an cDepartment of General Surgery, Bazhong Central Hospital, Bazhong, People's Republic of - - 2014
Because of an increasing aging population worldwide, a greater number of elderly patients are being considered for hepatic resection. The objective of this retrospective pair-matched study was to assess the influence of age on postoperative outcomes after major hepatectomy (resection of three or more Couinaud segments) in elderly patients with ...
Fang Qi-Gen QG Resident, Department of Oromaxillofacial-Head and Neck Surgery, China Medical University School of Stomatology, Heping District, Shenyang, Liaoning, People's Republic of - - 2014
Our goal was to evaluate whether elderly patients can benefit from free flaps. The clinical information from the included patients was reviewed, and these patients were asked to complete the University of Washington Quality of Life, version 4, questionnaire. Comparisons of the different scales between the 2 groups were performed. ...
Qian Q Q Department of Colorectal Surgery, Hubei Key Laboratory of Intestinal and Colorectal Diseases, Clinical Research Center for Intestinal and Colorectal Diseases of Hubei Province, Zhongnan Hospital of Wuhan University, 169, Donghu Rd, Wuhan, 430071, - - 2014
The aim of this study was to evaluate outcomes of total colonic exclusion with antiperistaltic ileorectal anastomosis (TCE-AIA) for elderly patients with slow transit constipation (STC). Elderly patients (defined as age >65) who underwent TCE-AIA for severe idiopathic STC between 2009 and 2012 at our institution were identified. Postoperative outcomes ...
Tanawuttiwat Tanyanan T Cardiovascular Division, Department of Medicine, University of Miami Miller School of Medicine, - - 2014
To determine the incidence of new-onset atrial fibrillation (AF) associated with different methods of isolated aortic valve replacement (AVR): transfemoral (TF-), transapical (TA-) and transaortic (TAo-) catheter-based valve replacement and conventional surgical approaches. The relative incidences of AF associated with the various access routes for AVR have not been well ...
George Isaac I Division of Cardiothoracic Surgery, Columbia University College of Physicians and Surgeons, New York Presbyterian Hospital, New York, NY. Electronic address: - - 2014
Advanced age plays a major role in surgical risk algorithms; however, the outcomes data for the very elderly are lacking. We, therefore, evaluated the outcomes after surgical aortic valve replacement (SAVR) in nonagenarians (age, >90 years) at our institution during an 11-year period. The demographics, procedural details, and in-hospital outcomes ...
Murashita Takashi T Department of Cardiovascular Surgery, Kobe City Medical Center General Hospital, Kobe, Hyogo, - - 2014
Purpose: The number of elderly patients who require surgical treatment for mitral regurgitation (MR) is increasing. However, the feasibility and efficacy of mitral valve repair in elderly patients are unclear.Methods: We retrospectively reviewed 55 patients, aged ≥75 years, who underwent mitral valve repair for degenerative MR between 1991 and 2011. ...
Boddaert Jacques J Université Pierre et Marie Curie (UMRS 956, UMRS 1158), Paris, France ; Department of Geriatrics, Groupe hospitalier (GH) Pitié-Salpêtrière, Assistance Publique Hôpitaux de Paris (APHP), Paris, - - 2014
Elderly patients with hip fracture have a 5 to 8 fold increased risk of death during the months following surgery. We tested the hypothesis that early geriatric management of these patients focused on co-morbidities and rehabilitation improved long term mortality. In a cohort study over a 6 year period, we ...
Tripathy Swagata S Department of Trauma and Emergency Medicine, All India Institute of Medical Sciences, Bhubaneswar, India. Electronic address: - - 2014
To study the mortality and outcome of critically ill elderly patients in a developing country with focus on nutritional and socioeconomic status. A prospective study of 109 patients (215 screened) admitted consecutively to the intensive care unit from 2011 to 2012. Demographics, Acute Physiology and Chronic Health Evaluation (APACHE) II ...
Gotoda Takuji T Department of Gastroenterology and Hepatology, Tokyo Medical University, 6-7-1 Nishishinjuku, Shinjuku-ku, Tokyo, 160-0023, Japan, - - 2014
Propofol is rapidly increasing in use in many countries because endoscopists and patients report greater satisfaction with propofol than with conventional sedatives. However, propofol infusion during lengthy endoscopic procedures in elderly patients is still controversial. We investigated the safety of gastroenterologist-guided propofol sedation in elderly patients who underwent gastric endoscopic ...
Scheer Justin K JK University of California, San Diego, School of - - 2014
Object Spinal osteotomies for adult spinal deformity correction may include resection of all 3 spinal columns (pedicle subtraction osteotomy [PSO] and vertebral column resection [VCR]). The relationship between patient age and health-related quality of life (HRQOL) outcomes for patients undergoing major spinal deformity correction via PSO or VCR has not ...
Carlisle J B JB Anaesthetic Department, Torbay Hospital, Torquay, Devon, - - 2014
Mortality is a good measure of killing, but it is a poor measure of cure, palliation or the maintenance of function. Nevertheless, it has remained the primary metric of hospital care for 200 years. This article discusses the factors that contribute to mortality risk and survival trajectories, as well as the ...
Vassileva Christina M CM Department of Surgery, Southern Illinois University School of Medicine, Springfield, Ill. Electronic address: - - 2014
Elderly patients are under-represented in most surgical series of mitral valve surgery. The impact of preoperative heart failure (HF) on the outcomes of this subset has not been extensively studied. The study included 45,082 Medicare beneficiaries who underwent primary isolated mitral valve repair (MVP) (n = 16,850) or replacement (MVR) (n = 28,232) from ...
Higuchi Toru T Departments of Internal Medicine and Gastrointestinal Endoscopy, Saga Medical School, - - 2014
Objective The present study was conducted using data accumulated from our earlier study of bleeding peptic ulcers, focusing on elderly patients. Methods A total of 461 patients with bleeding peptic ulcers underwent emergency endoscopy at Saga Medical School Hospital between 1999 and 2011. Risk factors for bleeding peptic ulcers were ...
Chen Tzu-Hsuan TH Department of Rehabilitation, Mackay Memorial Hospital, Hsinchu, - - 2014
The use of insoles may enhance postural stability and prevent falls. The aim of this study was to design a new insole and to explore the effectiveness of the insole on the standing balance of the healthy elderly. The study was conducted at a community hospital. Patients older than 65 ...
Mignardot Jean-Baptiste JB Laboratory "Motricité, Interactions, Performance" (UPRES EA 4334), University of Nantes Nantes, France ; Up-COURTINE Lab, Centre for Neuroprosthetics and Brain Mind Institute, Ecole Polytechnique Fédérale de Lausanne Lausanne, - - 2014
Falls are common in the elderly, and potentially result in injury and disability. Thus, preventing falls as soon as possible in older adults is a public health priority, yet there is no specific marker that is predictive of the first fall onset. We hypothesized that gait features should be the ...
Chaudhary A A Department of Anesthesia, KG's Medical University, Lucknow, Uttar Pradesh, - - 2014
The low-dose ropivacaine provides differential spinal block to reduce adverse hemodynamic effects in elderly patients. Addition of intrathecal fentanyl with ropivacaine may enhance analgesia and early postoperative mobility. The present study was performed to evaluate the efficacy of intrathecal ropivacaine alone and in combination with fentanyl in transurethral resection operation. ...
Meineke Minhthy - - 2014
As life expectancy increases, more patients ≥65 years undergo general anesthesia. Anesthetic agents may contribute to postoperative cognitive dysfunction, and incidence may differ with anesthetic agents or intraoperative anesthesia depth. Responses to anesthetic adjuvants vary among elderly patients. Processed electroencephalography guidance of anesthetic may better ensure equivalent cerebral suppression. This study ...
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