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Garg Jalaj J 1Department of Medicine, Division of Cardiology, Westchester Medical Center, New York Medical College, Valhalla, NY; and 2Department of Pathology, Westchester Medical College, New York Medical College, Valhalla, - - 2014
St. Jude mechanical prosthesis is the most commonly used prosthetic device with least valvular complications with excellent hemodynamics. However, prosthetic valve thrombosis is one of the serious complications, with rates between 0.03% and 0.13% per patient-year depending on the type of anticoagulation used and compliance to the therapy. Transthoracic echocardiography ...
Virginio Vitor W M - - 2014
ABSTRACT Introduction: Cholesterol undergoes oxidation via both enzymatic and free radicals-mediated mechanisms, generating a wide range of oxysterols. In contrast with oxidative stress-driven metabolites, enzymatic-derived oxysterols are scarcely studied in their association with atherosclerotic disease in humans. Methods: 24S-hydroxycholesterol (24S-HC), 25-hydroxycholesterol (25-HC), and 27-hydroxycholesterol (27-HC) were assessed in plasma and ...
Sorrentino Thomas A - - 2014
Glycosaminoglycans are increasingly thought to play important roles in arterial mechanics and mechanobiology. We recently suggested that these highly negatively charged molecules, well known for their important contribution to cartilage mechanics, can pressurize the intralamellar units within elastic arteries and thereby impact smooth muscle mechanosensing in vivo. In this paper, ...
Jonas Michael M Kaplan Medical Center, Rehovot, - - 2014
Aims: To demonstrate the feasibility of the Leaflex™ Catheter System, a novel percutaneous device for fracturing valve calcification using mechanical impact in order to regain leaflet mobility. Methods and results: Radiographic analysis of calcium patterns in 90 ex vivo human aortic valve leaflets demonstrated that 82% of leaflets had a ...
Dass Param P Department of Vascular Surgery, Auckland City Hospital, New Zealand - - 2014
Percutaneous mechanical rheolytic thrombectomy is an effective treatment option for deep vein thrombosis as well as arterial and graft thromboses. Acute pancreatitis, a rare complication of this technique, is described in this case report. A 40-year-old man underwent AngioJet mechanical rheolytic thrombectomy for iliocaval deep vein thrombosis. He subsequently developed ...
Takamizawa Keiichi - - 2014
Few multi-axial constitutive laws under the vasoactive condition have been proposed as compared with those under the passive condition. The biaxial isometric properties of vasoactive rabbit arteries were studied although the constitutive law was not proposed. The purpose of the present study is also to describe the multi-axial active mechanical ...
Vizzardi E E Section of Cardiovascular Diseases, Department of Medical and Surgical Specialties, Radiological Sciences and Public Health, University of Study of Brescia, Brescia, Italy. - - 2014
Previous studies revealed that hypertrophic cardiomyopathy (HCM) patients have impaired aortic elastic properties with contrasting data about aortic dimensions. We aimed to extend our knowledge about this topic, considering tissue Doppler imaging (TDI) and tissue strain. 25 HCM patients and 25 healthy volunteers matched for age and sex were enrolled. ...
Fox Benjamin B Semmes-Murphey Neurologic and Spine Institute, Memphis, Tennessee, - - 2014
A patient with a giant symptomatic vertebrobasilar aneurysm was treated by endoscopic third ventriculostomy for obstructive hydrocephalus followed by treatment of the aneurysm by flow diversion using a Pipeline Embolization Device. After an uneventful procedure and initial periprocedural period, the patient experienced an unexpected fatal subarachnoid hemorrhage 1 week later. Autopsy ...
Amin Faisal F Biomedical Engineering and Sciences Department, School of Mechanical and Manufacturing Engineering, National University of Sciences and Technology (NUST), Islamabad - - - 2014
Cardiovascular heart disease is one of the leading health issues in the present era and requires considerable health care resources to prevent it. The present study was focused on the development of a new coronary stent based on novel auxetic geometry which enables the stent to exhibit a negative Poisson's ...
Razaghi R R School of Mechanical Engineering, Iran University of Science and Technology, Tehran, Iran Tissue Engineering and Biological Systems Research Lab, School of Mechanical Engineering, Iran University of Science and Technology, Tehran, - - 2014
Implantation of a stent into a stenotic artery is almost a purely mechanical process. The success of this process is largely correlated to the arterial and plaque component mechanical properties. The mechanical properties of animals' arteries, so far, have been typically employed in stent simulation studies. However, it has been ...
Lee Avione Y AY Department of Mechanical Engineering, The University of Texas at San Antonio, Biomedical Engineering Program, UTSA-UTHSCSA, San Antonio, TX, United - - 2014
Tortuous arteries associated with aneurysms have been observed in aged patients with atherosclerosis and hypertension. However, the underlying mechanism is poorly understood. The objective of this study was to determine the effect of aneurysms on arterial buckling instability and the effect of buckling on aneurysm wall stress. We investigated the ...
Jana Soumen S Division of Cardiovascular Diseases, Mayo Clinic, 200 First Street SW, Rochester, MN 55905, - - 2014
Over the last 50years medicine and technology have progressed to the point where it has become commonplace to safely replace damaged or diseased heart valves with mechanical and biological prostheses. Despite the advancements in technology current valve substitutes continue to have significant limitations with regards to thrombogenicity, durability, and inability ...
Xu Zhiwei Z Department of Cardiac Surgery, Beijing Anzhen Hospital, Capital Medical University, Beijing, China Department of Cardiac Surgery, The Affiliated Hospital of Hangzhou Normal University, Hangzhou, - - 2014
To determine the effects of implanting a novel mosaic tissue-engineered porcine pulmonary artery valved conduit into the right ventricular outflow tract of sheep at a long-term follow-up. The designed mosaic tissue-engineered porcine pulmonary artery valved conduits were implanted between the right ventricular outflow tract and distal pulmonary artery in sheep ...
Pauck R G RG Biomedical Engineering, Department of Human Biology, University of Cape Town (UCT), South Africa; Centre for Research in Computational and Applied Mechanics (CERECAM), UCT, South Africa. Electronic address: - - 2014
Stents have been an effective tool to restore and maintain the patency of narrowed blood vessels, but they must have sufficient radial strength. Biodegradable stent materials have substantially lower mechanical properties than permanent stents. The stent geometry and material properties must be considered simultaneously when assessing stent performance. Material tests ...
Pierce David M DM Departments of Mechanical Engineering, Biomedical Engineering and Mathematics, University of Connecticut, CT, - - 2014
Development of aortic aneurysms includes significant morphological changes within the tissue: collagen content increases, elastin content reduces and smooth muscle cells degenerate. We seek to quantify the impact of these changes on the passive mechanical response of aneurysms in the supra-physiological loading range via mechanical testing and constitutive modeling. We ...
Kawajiri Hidetake H Division of Medical Engineering and Materials, National Cerebral and Cardiovascular Center Research Institute, 5-7-1 Fujishiro-dai, Suita, 565-8565, Japan, - - 2014
The use of stent grafts for endovascular aortic repair has become an important treatment option for aortic aneurysms requiring surgery. This treatment has achieved excellent outcomes; however, problems like type 1 endoleaks and stent graft migration remain. Bio stent grafts (BSGs), which are self-expanding stents covered with connective tissue, were ...
Lim Hong-Gook HG Seoul National University Hospital Clinical Research Institute, Xenotransplantation Research Center, Seoul, Republic of Korea Department of Thoracic and Cardiovascular Surgery, Seoul National University Hospital, Seoul National University College of Medicine, Seoul, Republic of - - 2014
Conventional crosslinking with glutaraldehyde (GA) renders cardiac xenografts inert, non-biodegradable and non-antigenic, but is a main cause for dystrophic calcification due to phospholipids, free aldehyde groups and residual antigenicity. A significant immune reaction to the galactose-α-1,3 galactose β-1,4-N-acetylglucosamine (α-Gal) of a GA-fixed cardiac xenograft occurs, leading to calcification. We developed ...
Hopkins Alan A AA Trinity Centre for Bioengineering, Trinity Biomedical Sciences Institute, 152-160 Pearse Street, Trinity College Dublin, Dublin 2, Ireland; Department of Mechanical and Manufacturing Engineering, School of Engineering, Trinity College Dublin, Dublin 2, Ireland. Electronic address: - - 2014
The aim of this study was to determine the effect that a thermal renal denervation cycle has on the mechanical properties of the arterial wall. Porcine arterial tissue specimens were tested in three groups: native tissue, decellularized tissue, decellularized with collagen digestion (e.g. elastin only). One arterial specimen was used ...
Medsinge Avinash A 1 All authors: Department of Diagnostic Radiology, Division of Interventional Radiology, University of Pittsburgh Medical Center, 200 Lothrop St, Pittsburgh, PA - - 2014
OBJECTIVE. The objective of this article is to familiarize the reader with the most commonly used embolic agents in interventional radiology and discuss an approach for selecting among the different embolic agents. This article reviews their properties and uses a case-based approach to explain how to select one. CONCLUSION. A ...
Chang Stephen Ky SK Department of Surgery, National University Hospital, - - 2014
The study seeks to investigate how the duration of storage of cryopreserved human cadaveric iliac arteries impacts their mechanical, structural and microbiological properties as compared to their fresh sample. Iliac arteries were harvested from 12 human cadavers and divided into 2 groups. One group underwent mechanical stress-strain assessment immediately and ...
Cunnane E M EM Centre for Applied Biomedical Engineering Research, Department of Mechanical, Aeronautical, and Biomedical Engineering, Material and Surface Science Institute, University of Limerick, Limerick, - - 2014
The failure of endovascular treatments of peripheral arterial disease represents a critical clinical issue. Specialised data are required to tailor such procedures to account for the mechanical response of the diseased femoral arterial tissue to medical device deployment. The purpose of this study is to characterise the mechanical response of ...
Kwon Kie Tae KT Department of Electrical Engineering, Magnetic Resonance Systems Research Laboratory, Stanford University, Stanford, California, - - 2014
To develop a new sequence for non-contrast-enhanced peripheral angiography using a sliding interleaved cylinder (SLINCYL) acquisition. A venous saturation pulse was incorporated into a three-dimensional magnetization-prepared balanced steady-state free precession sequence for non-contrast-enhanced peripheral angiography to improve artery-vein contrast. The SLINCYL acquisition, which consists of a series of overlapped thin ...
O'Leary Siobhan A SA Mechanical, Aeronautical and Biomedical Engineering Department, MSG-013-020, Centre for Applied Biomedical Engineering Research, Materials and Surfaces Science Institute, University of Limerick, Limerick, Ireland, - - 2014
Rupture of the abdominal aortic aneurysm (AAA) occurs when the local wall stress exceeds the local wall strength. Knowledge of AAA wall mechanics plays a fundamental role in the development and advancement of AAA rupture risk assessment tools. Therefore, the aim of this study is to evaluate the biaxial mechanical ...
Sişman A Sezim AS Department of Otorhinolaryngology, Istanbul Training and Research Hospital, Istanbul, - - 2014
Despite the importance of its location, the functional behavior of the nasal septal turbinate (NST) is still not completely understood. Basic histological knowledge is still lacking. The aim of this study was to describe the histological features of the NST and to compare its morphometric features to those of the ...
Takahara Akira A Department of Pharmacology and Therapeutics, Faculty of Pharmaceutical Sciences, Toho University, - - 2014
The pulmonary vein has a unique electrophysiological property showing an autonomic electrical activity, and this phenomenon has been further focused on as a source of triggers of atrial fibrillation. The pulmonary vein cardiomyocytes have shorter action potential duration, less negative resting membrane potential, and smaller maximum upstroke velocity than those ...
Takahara Akira A Department of Pharmacology and Therapeutics, Faculty of Pharmaceutical Sciences, Toho University, - - 2014
The pulmonary vein has a unique electrophysiological property showing an autonomic electrical activity, and this phenomenon has been further focused on as a source of triggers of atrial fibrillation. The pulmonary vein cardiomyocytes have shorter action potential duration, less negative resting membrane potential, and smaller maximum upstroke velocity than those ...
Acharya Gayathri - - 2014
Native, allograft, xenograft and bioprosthetic semilunar valves are all susceptible to calcific degeneration. However, intrinsic differences in baseline calcium and phosphorus tissue concentrations within mammalian normal valve structural components (e.g., cusps, sinus, vessel wall) additionally subdivided by tripartite regions (e.g., right-, left- and non-coronary leaflets) have never been systematically measured ...
Spadaccio Cristiano - - 2014
The majority of approaches currently described and practiced in mitral repair surgery result in the vertical immobilization of the posterior leaflet, with the anterior leaflet striving to produce an adequate coaptation. Despite the satisfactory hemodynamic outcome and disappearance of mitral regurgitation, this non-physiological situation results in a redistribution of forces ...
Watanabe Yoshiki Y Department of Cardiovascular Surgery, Osaka University Graduate School of Medicine, Osaka, - - 2014
Stent graft-related complications, including endoleaks and graft migration, are partly attributed to insufficient graft attachment to the aortic wall. ONO-1301, a stable synthetic prostacyclin agonist, reportedly reorganizes extracellular matrices, enhancing tissue healing. We hypothesized that ONO-1301-eluting stent grafts may strengthen graft attachment to the aortic wall. Polylactic acid polymer-conjugated ONO-1301, ...
Takeuchi Mugiho M Department of Cardiovascular Surgery, Osaka University Graduate School of Medicine, Osaka, - - 2014
To prevent postoperative migration and endoleaks after endovascular aneurysm repair, we developed a tissue-engineered vascular graft that integrates with the aortic wall by recruiting the host tissue into the graft scaffold. In the present study, we assessed the mechanical properties of the new graft and evaluated the integration between the ...
Chao Chia-Ter CT Renal Division, Department of Internal Medicine, National Taiwan University Hospital Jin-Shan Branch, New Taipei, Taiwan, - - 2014
Objective: To present a case of Salmonella bacteremia with a rare metastatic focus. Clinical Presentation and Intervention: A 61-year-old male presented with a suicide attempt after ingestion of half a bottle of toilet cleaner. He had a medical history of intravenous drug abuse and major depression. Persistent Salmonella enteritidis bacteremia ...
Moser Bernhard B Department of Thoracic Surgery, Division of Surgery, Medical University Vienna, Vienna, - - 2014
The molecular determinants of chronic thromboembolic pulmonary hypertension (CTEPH) and idiopathic pulmonary arterial hypertension (iPAH) remain poorly understood. The receptor for advanced glycation endproducts (RAGE) and its ligands: HMGB1 and S100A9 are involved in inflammatory disorders. We sought to investigate the role of the RAGE axis in patients with CTEPH ...
Veshkina Natalia N Faculty of Process and Environmental Engineering, Lodz Technical University, 213 Wólczanska St.,90-924 Lodz, - - 2014
In this study, a fluid-structure interaction analysis based on the application of patient-specific mechanical parameters of the aneurismal walls was carried out to predict the rupture side during an abdominal aortic aneurysm (AAA). Realistic geometry of the aneurysm was reconstructed from CT data acquired from the patient, and patient-specific flow ...
Arcucci A A University of Naples Federico II. - - 2014
Ascending aortic aneurysm (AsAA) is a consequence of medial degeneration (MD), deriving from apoptotic loss of smooth muscle cells (SMC) and fragmentation of elastin and collagen fibers. Alterations of extracellular matrix structure and protein composition, typical of medial degeneration, can modulate intracellular pathways. In this study we examined the relevance ...
Granada Juan F JF Skirball Center for Cardiovascular Research, Cardiovascular Research Foundation , Orangeburg, New York , - - 2014
The efficacy of paclitaxel-coated balloons (PCB) for restenosis prevention has been demonstrated in humans. However, the mechanism of action for sustained drug retention and biological efficacy following single-time drug delivery is still unknown. The pharmacokinetic profile and differences in drug concentration (vessel surface vs arterial wall) of two different paclitaxel ...
Fox Benjamin B Semmes-Murphey Neurologic and Spine Institute, Memphis, Tennessee, - - 2014
A patient with a giant symptomatic vertebrobasilar aneurysm was treated by endoscopic third ventriculostomy for obstructive hydrocephalus followed by treatment of the aneurysm by flow diversion using a Pipeline Embolization Device. After an uneventful procedure and initial periprocedural period, the patient experienced an unexpected fatal subarachnoid hemorrhage 1 week later. Autopsy ...
Schneider Joachim J Institute and Outpatient Clinic for Occupational and Social Medicine, University Medical Center Giessen, Aulweg 129/III, D-35385 Giessen, - - 2014
An 81-year-old woman was dying from histologically confirmed pulmonary fibrosis without having had any asbestos exposure in the workplace. The lung dust fibre analysis showed significantly increased "asbestos bodies" (AB) (2,640 AB per gram of wet lung tissue) and asbestos fibre concentrations (8,600,000 amphibole fibres of all lengths and 540,000 ...
Rebelo Rita R Fibrous Materials Research Group - Centre for Textile Science and Technology, University of Minho, 4800-058 Guimarães, - - 2014
The mechanical behavior of stents is one of the important factors involved in ensuring their function in maintaining an open blood vessel. This study aims to study the development of different kinds of fiber-based stents, using braiding technology. Moreover, the impact of braiding angle and mandrel's diameter in the mechanical ...
Rittayamai Nuttapol N Division of Respiratory Diseases and Tuberbulosis, Department of Medicine, Faculty of Medicine Siriraj Hospital, Mahidol University Bangkok, - - 2014
Pulmonary alveolar microlithiasis is a rare pulmonary disorder that is caused by abnormal sodium-dependent phosphate co-transporter from the mutation of SLC34A2 gene, leading to accumulation of microliths in the alveoli. We report the extensive pulmonary alveolar microlithiasis in an elderly woman who presented with progressive dyspnea for 2 months. Chest ...
Ho Man Fung MF Division of Vascular & Endovascular Surgery, Department of Surgery, University of Hong Kong Medical Centre, Queen Mary Hospital, Hong - - 2013
We report the management of a case of thigh abscess with ruptured left superficial femoral artery mycotic aneurysm in a 91-year-old woman with significant comorbidity. The abscess culture grew Escherichia coli and Acinetobacter baumannii. Vascular reconstruction was not performed because the foot was viable with a heavily contaminated wound. The ...
Reichlin Tobias - - 2012
Maximizing Lesion Durability in PVI. Recurrence of atrial fibrillation (AF) after a single ablation procedure has been reported in the range of 15-60% depending on patient selection. A major factor leading to AF recurrence after catheter ablation therapy is electrical reconnection of one or more pulmonary veins (PVs) due to recovery ...
Akiyama Takenori - - 2012
Spontaneous occlusion is a rare manifestation of ruptured vertebral artery dissection (VAD). Its natural history and treatment strategy have yet to be established due to its rarity. Here, we report five lesions involving spontaneous occlusion of VAD after subarachnoid haemorrhage, among which three lesions showed recanalisation. Based on our experience ...
Kobayashi Daisuke - - 2012
A 4-month-old infant with trisomy 21 and repaired complete atrioventricular septal defect developed endocarditis with methicillin-resistant Staphylococcus aureus in the early postoperative period. We report the successful replacement of the common atrioventricular valve with a single St. Jude mechanical prosthetic valve, along with an intraluminal pulmonary artery banding to restrict ...
Demirkol Sait - - 2012
Atrioventricular valve parachute deformity was generally seen in the mitral position, which is called parachute mitral valve. Parachute deformity is also seen in the tricuspid position, but this has rarely been reported as sporadic cases. All of these cases were associated with other congenital defects, such as double outlet right ...
Ash Stephen R - - 2012
A 75-year-old man on chronic peritoneal dialysis had unrecognized stenosis of the superior vena cava (SVC) due to pacemaker wires placed 5 years earlier. The patient was placed on hemodialysis after hernia surgery. When a tunneled central venous catheter for dialysis was placed from the right internal jugular (IJ) vein, ...
Burger Berdine M - - 2012
A 39-year-old white man presented with intractable headaches and papilledema. The initial workup, with normal MRI and MRV but elevated cerebrospinal fluid protein raised concerns about the putative diagnosis of idiopathic intracranial hypertension, and his condition remained refractory to maximum medical treatment. Angiography revealed cerebral venous sinus stenosis, thought to ...
Hong Jung Min - - 2012
We report a case of a patient with a double-primary aortoenteric fistula with an abdominal aortic aneurysm. A 75-year-old man was taken to the operating room for the repair of an abdominal aortic aneurysm and a suspected aortoenteric fistula between the aorta and sigmoid colon. Sudden onset of massive bleeding ...
Johns S M - - 2012
BACKGROUND: Congestive heart failure (CHF) in cats with left-sided heart disease is sometimes manifest as pleural effusion, in other cases as pulmonary edema. HYPOTHESIS: Those cats with pleural effusion have more severe left atrial (LA) dysfunction than cats with pulmonary edema. ANIMALS: 30 healthy cats, 22 cats with pleural effusion, ...
Tran Cam Ha T - - 2012
Electrical communication and its role in blood flow regulation are built on an examination of charge movement in single, isolated vessels. How this process behaves in broader arterial networks remains unclear. This study examined the nature of electrical communication in arterial structures where vessel length and branching were varied. Analysis ...
Lim Kyung-Jee - - 2012
Background:If full expiration during subclavian venous cannulation increases the distance between the subclavian vein (SCV) and the pleura or increases the diameter of the vein, it might decrease the incidence of pneumothorax and/or increase the success rate of venous cannulation. In this study, we evaluated the effect of full expiration ...
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