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Chang Sung-A - - 2011
Hereditary hemorrhagic telangiectasia (HHT) is a hereditary vascular disease with multiple arterial venous malformations. Pulmonary arterial hypertension is occasionally associated with HHT; however, there is no evidence of targeted therapy for this subgroup of patients. This report describes a 37-year-old woman who presented with dyspnea on exertion. She was finally ...
Erdogan Serkan - - 2010
This study aims to determine morphological features of certain aural formations, varietal characteristics, and arterial supply in fetal development period in cattle. For this purpose, ears of 10 bovine fetuses in mid-gestation were evaluated. Organ morphology and vascularization in prenatal life were investigated by using corrosion cast technique. It was ...
Matschke Jakob - - 2010
Sudden unexpected death is any nontraumatic death in healthy individuals with normal activities for age until acute demise. Whereas not uncommon in adults and infants, it is considered a rarity in children, with most cases due to infection or occult cardiovascular abnormalities. Pathologic intracranial findings are rarely found in sudden ...
He Bei - - 2010
ObjectiveTo investigate the changes on carotid artery of patients with acute ischemic stroke by dual source computed tomographic angiography (DS-CTA) . MethodsFrom March 2009 to August 2010, 71 patients with acute ischemic stroke (IS group) underwent magnetic resonance imaging, which showed high signals on diffusion-weighted images. The location of atherosclerotic ...
Hokari Masaaki - - 2011
Several prospective studies have shown that carotid endarterectomy can reduce the risk for subsequent ischemic stroke in patients with 70-99% stenosis of the internal carotid artery (ICA). However, its benefits are still controversial in less than 70% stenosis of the ICA. There is increasing evidence that carotid lumen irregularities may ...
Agasthian Thirugnanam - - 2010
Transcervical thymectomy is a standard approach to the thymus and anterior mediastinum, but it is limited by poor exposure of the lower recesses of the anterior mediastinum. A novel technique using the widely available internal thoracic artery sternal retractor and a 30°-video camera allows enhanced exposure of the anterior mediastinum.
Ahn Seong Hwan - - 2010
Arteriovenous malformations (AVMs) with vascular abnormalities, including aneurysms, have been reported frequently. However, the coexistence of AVM and unilateral moyamoya disease is rare. We report herein an AVM patient who presented with acute ischemic stroke with unilateral moyamoya disease and occlusion of the feeding artery. A-41-year old man was admitted ...
Brumback Lyndia C LC Department of Biostatistics, University of Washington, Seattle, WA 98195, USA. - - 2010
The aim of this report was to describe the reproducibility of arterial elasticity parameters derived from radial artery diastolic pulse contour analysis. Two measurements were taken on the same day by the same technician with the HDI/Pulsewave CR-2000 System on each of a subset of participants selected randomly from the ...
Ni Jun - - 2011
Stroke risk of asymptomatic atherosclerotic middle cerebral artery (MCA) stenosis has not been well studied. This study was designed to investigate stroke risk and prognostic factors of asymptomatic atherosclerotic MCA stenosis. A total of 200 consecutive patients who visited the transcranial Doppler ultrasound (TCD) laboratory of our hospital and who ...
Jiang Lindi - - 2012
To measure and assess the disease activity of Takayasu arteritis (TA) quantitatively by magnetic resonance angiography (MRA). Twenty-six Chinese TA patients were divided into an active group and an inactive group. All patients underwent delayed contrast-enhanced MRI. The vessels involved were categorized into type A (main branches of aorta and ...
Christen Alejandra I - - 2010
Type 2 Diabetes Mellitus (DM), or adult-onset diabetes, is being considered as a new pandemic. Cardiovascular disease is the major cause of morbidity and mortality in type 2 DM, due to arterial structure and functional changes. Assessment of arterial structure and biomechanics, by non-invasive methods and parameters, can be used ...
Doenitz Christian - - 2010
Despite technical and diagnostic progress there are still open questions in the understanding of the pathophysiology of intracranial aneurysms. Within 44 days we observed the de novo genesis and rupture of an aneurysm of the basilar artery in a patient. We performed computational fluid dynamics on 3-dimensional (3D) models of ...
Yilmaz O─čuz - - 2010
Endovascular stent-grafting of the aorta, as an alternative to open surgical techniques, is gaining in popularity everyday, especially in high-risk patients. Acute or chronic traumatic lesions of the descending aorta, especially after motor vehicle accidents, constitute such a group with a high-risk of morbidity and mortality. Here, we report the ...
Samouillan Valerie - - 2010
Abdominal aortic aneurysms (AAA) are characterized by structural alterations of the aortic wall resulting from the degradation of elastic fibres and an increase of collagen/elastin ratio. In this study we investigated the chain dynamics of AAA tissues by two techniques generally used for the characterization of polymers, Differential scanning calorimetry ...
Zhang Qi - - 2010
The detailed geometry of atherosclerosis-prone vascular segments may influence their susceptibility by mediating local hemodynamics. An appreciation of the role of specific geometric variables is complicated by the considerable correlation among the many parameters that can be used to describe arterial shape and size. Factor analysis is a useful tool ...
Esmer A F - - 2010
We aimed to study the neurovascular relationships between the anterior inferior cerebellar artery (AICA) and the abducens nerve to help determine the pathogenesis of abducens nerve palsy which can be caused by arterial compression. Twenty-two cadaveric brains (44 hemispheres) were investigated after injected of coloured latex in to the arterial ...
Chappell Michael A MA Oxford Centre for Functional MRI of the Brain, University of Oxford, John Radcliffe Hospital, Headington, Oxford, United Kingdom. - - 2010
Vessel encoded arterial spin labeling provides a way to perform non-invasive vascular territory imaging. By uniquely encoding the blood within feeding arteries over a number of images, the territories of each can be identified. Here, a new approach for the analysis of vessel encoded arterial spin labeling data is presented. ...
Michel Jean-Baptiste - - 2011
Aneurysm of the abdominal aorta (AAA) is a particular, specifically localized form of atherothrombosis, providing a unique human model of this disease. The pathogenesis of AAA is characterized by a breakdown of the extracellular matrix due to an excessive proteolytic activity, leading to potential arterial wall rupture. The roles of ...
Mata Karina M - - 2011
Progress in understanding the pathophysiology of abdominal aortic aneurysms (AAA) is dependent in part on the development and application of effective animal models that recapitulate key aspects of the disease. The objective was to produce an experimental model of AAA in rats by combining two potential causes of metalloproteinase (MMP) ...
Tulamo Riikka - - 2010
Inflammation and activation of the complement system predispose to intracranial artery aneurysm (IA) rupture. Because disturbances in complement regulation may lead to increased susceptibility to complement activation and inflammation, we looked for evidence for dysregulation of the complement system in 26 unruptured and 26 ruptured IAs resected intraoperatively. Immunohistochemical and ...
Rafiq Isma - - 2011
First case of infective endocarditis on a percutaneous aortic valve replacement due to Moraxalla nonliquefaciens in 64 year old woman. It was successfully treated medically with antibiotics. She had not suitable for surgical aortic valve replacement due to 3 sternotomies for thymoma resection and subsequent radiotherapy with blocked major thoracic ...
Lee Hae-Young - - 2010
Arterial walls stiffen with age. The most consistent and well-reported changes are luminal enlargement with wall thickening and a reduction of elastic properties at the level of large elastic arteries. Longstanding arterial pulsation in the central artery causes elastin fiber fatigue and fracture. Increased vascular calcification and endothelial dysfunction are ...
Meng Hui H Departments of Mechanical and Aerospace Engineering, University at Buffalo, The State University of New York, Buffalo, New York 14214, USA. - - 2011
Hemodynamic insult has been speculated to be a key factor in intracranial aneurysm formation; however, it is unclear whether a sustained insult is necessary. The authors examined whether aneurysmal degradation would continue despite the normalization of wall shear stress (WSS) by adaptive outward vascular remodeling. Twenty-five rabbits underwent either sham ...
Tracy Richard Everett - - 2011
Hypertrophied hearts at autopsy often display excessive coronary artery atherosclerosis, but the histopathology of coronary arteries in hearts with and without cardiomegaly has rarely been compared. In this study, forensic autopsies provided hearts with unexplained enlargement plus comparison specimens. Right coronary artery was opened longitudinally and flattened for formalin fixation ...
Maor Elad - - 2010
To evaluate the effect of endovascular nonthermal irreversible electroporation (NTIRE) on blood vessels. Specially made endovascular devices with four electrodes on top of inflatable balloons were used to apply electroporation pulses. Finite element simulations were used to characterize NTIRE protocols that would not induce thermal damage to treated tissues. Right ...
Urban Matthew W - - 2010
Arterial elasticity has gained importance in the past decades as it has been shown to be an independent predictor of cardiovascular diseases. Ultrasound radiation force has been used to excite propagating waves in arterial vessels in order to measure the wave speeds and characterize the elastic properties of the vessels. ...
Duran N E - - 2010
The relationship between venous thrombosis (VT) and atherosclerosis is controversial in recent studies. Aortic elastic properties have a predictive value in detecting early stages of atherosclerosis. The aim of this study is to evaluate the relationship between aortic elastic properties and VT. Elastic properties of aorta in patients with spontaneous ...
Chen Ko-Ron - - 2010
The presence of an internal elastic lamina and a compact concentric muscular layer are the cardinal histologic clues for distinguishing a small muscular artery from small muscular vein. However, the subcutaneous muscular veins in the lower legs usually have thick muscular layers with the proliferation of concentric intimal elastic fibers, ...
Couade Mathieu - - 2010
A new ultrasound-based technique is proposed to assess the arterial stiffness: the radiation force of an ultrasonic beam focused on the arterial wall induces a transient shear wave (∼10 ms) whose propagation is tracked by ultrafast imaging. The large and high-frequency content (100 to 1500 Hz) of the induced wave ...
Orhan Mustafa - - 2010
One of the most effective treatments of inferior turbinate (IT) hypertrophy is surgical reduction. Bleeding from the IT branch of the posterior lateral nasal artery (ITB) may interfere with the outcome of IT surgery. The aim of this study is to define the anatomic localization of the ITB and its ...
Franz Thomas - - 2010
External mesh constriction of vein grafts was shown to mitigate intimal hyperplasia by lowering circumferential wall stress and increasing fluid shear stress. As under-constriction leaves vein segments unsupported and thus prone to neointimal proliferation while over-constriction may cause wall folding optimal mesh sizing holds a key to clinical success. Diameter ...
Eberth John F - - 2010
Elucidating early time courses of biomechanical responses by arteries to altered mechanical stimuli is paramount to understanding and eventually predicting long-term adaptations. In a previous study, we reported marked long-term (at 35-56 days) consequences of increased pulsatile hemodynamics on arterial structure and mechanics. Motivated by those findings, we focus herein ...
Ueda Kazunori - - 2010
Although the devices for large-caliber vessel (>2-mm diameter) anastomosis are available, there are no devices for performing anastomosis of small-caliber vessels. We designed a hooked device composed of a bioabsorbable polymer for sutureless anastomosis of small-caliber vessels. The efficacy of this device was evaluated by in vitro degradation and arterial-fixation ...
Pan Wei-Ren - - 2010
Previously little has been written about the morphology of the human lymphatic vessels since Sappey (Sappey [1874] Anatomie, Physiologie, Pathologie des Vaisseaux Lymphatiques, Paris: Adrien Delahaye) over 100 years ago. There needs to be an accurate re-evaluation of scientific observations to aid clinical management. Forty-nine combinations of tissue from the ...
Cinthio Magnus - - 2010
Arterial diameter change is related to distending blood pressure and is used in estimation of arterial stiffness parameters. A common technique to track the arterial walls is by integration of wall velocities estimated by different methods using cross correlation or tissue Doppler. However, because of the high pulse repetition frequency ...
Sutin Angelina R - - 2010
A large body of evidence links antagonism-related traits with cardiovascular outcomes, but less is known about how psychological traits are associated with intermediate markers of cardiovascular disease. Using a large, community-based sample from Sardinia, Italy (n=5614), this study examined how trait antagonism (low agreeableness) and its facets are associated with ...
Adachi Iki - - 2010
In the past, pulmonary arterial (PA) structure has been extensively investigated with the aim of providing an insight into operative indication for patients with congenital heart disease (CHD). Although PA histological analysis is applied less frequently in the current era, demographic changes of CHD patients require a refocussing of attention. ...
Karmonik Christof - - 2010
To assess reliability of wall shear stress (WSS)calculations using computational fluid dynamics (CFD) dependent on inflow in internal carotid artery aneurysms (ICA). Six unruptured ICA aneurysms were studied. 3D computational meshes were created from 3D digital subtraction angiographic images (Axiom Artis dBA, Siemens Medical Solutions). Transient CFD simulations(Fluent, ANSYS Inc.) ...
Duprez Daniel A - - 2010
Early cardiovascular disease starts in the endothelium leading to functional changes in the vasculature. These changes can be depicted by assessment of arterial stiffness or elasticity. There are several techniques to assess arterial stiffness. Increased arterial stiffness or decreased arterial elasticity has been associated with cardiovascular risk factors. There is ...
Leguy C A D - - 2010
To estimate arterial stiffness, different methods based either on distensibility, pulse wave velocity or a pressure-velocity loop, have been proposed. These methods can be employed to determine the arterial mechanical properties either locally or globally, e.g. averaged over an entire arterial segment. The aim of this study was to investigate ...
van der Sanden Boudewijn - - 2010
PURPOSE: The purpose is to evaluate effects of a new radiotherapy protocol, microbeam radiation therapy, on the artery wall. In previous studies on animal models, it was shown that capillaries recover well from hectogray doses of X-rays delivered in arrays of narrow (< or = 50 microm) beams with a ...
Avril Stéphane - - 2010
In this paper, we present a new approach for the bi-axial characterization of in vitro human arteries and we prove its feasibility on an example. The specificity of the approach is that it can handle heterogeneous strain and stress distributions in arterial segments. From the full-field experimental data obtained in ...
Astor Brad C - - 2010
To determine the extent of thickening of the carotid arterial walls that may be accommodated by outward remodeling. Institutional review board approval was obtained at each participating site, and informed consent was obtained from each participant. All study sites conducted this study in compliance with HIPAA requirements. A total of ...
Naso Filippo - - 2010
Evaluation of the physiological performance of biological scaffolds for tissue engineering applications has been mostly based on biophysical and morphological methods, with limited attention paid to the quantitative contribution of the main structural components to native and/or treated valve assemblies. In the present study quantitation addressed the porcine leaflet, sinus ...
Modak Raj K - - 2010
To evaluate in vivo cross-sectional conformational changes of ascending aortic wall excursion in patients undergoing resection for aortic aneurysm with those undergoing elective coronary artery bypass grafting (CABG) using epi-aortic echocardiography. A prospective observational investigation. A single tertiary care university hospital. Thirty-four patients undergoing elective ascending aorta resection and 23 ...
Forte Amalia - - 2010
Myofibroblasts (MFs) are contractile cells deriving from a multiplicity of resident cells and/or circulating progenitors that are known to play a key role in wound healing. They were first discovered and analysed in the early 1970s in granulation tissue. Since their first identification, the role of MF and their mechanisms ...
Wan William - - 2010
Alteration in the mechanical properties of arteries occurs with aging and disease, and arterial stiffening is a key risk factor for subsequent cardiovascular events. Arterial stiffening is associated with the loss of functional elastic fibers and increased collagen content in the wall of large arteries. Arterial mechanical properties are controlled ...
Sarkola Taisto - - 2010
High-resolution ultrasound (HRU) is used to measure carotid intima-media thickness (IMT). We postulated that very-high-resolution ultrasound (VHRU, 25-55MHz) provides more detailed information on arterial morphology. Rabbit and pig arterial specimens and artificial elastin membranes were studied with HRU and VHRU, and compared to histology. Bilateral carotid, brachial, radial, ulnar, femoral, ...
Koens M J W - - 2010
There is a consistent need for a suitable natural biomaterial to function as an arterial prosthesis in achieving arterial regeneration. Natural grafts are generally obtained by decellularization of native blood vessels, but batch to batch variations may occur and the nature/content of remaining contaminants is generally unknown. In this study ...
Rodríguez M - - 2011
Extracellular matrix deposition is the main factor inducing stenotic lesions in arterial grafts. Lysyl oxidases (LOX) play a key role in stabilizing collagen and elastin. To examine the repair response to arterial allografts in terms of LOX expression and collagen/elastin deposition using LOX inhibitors. Lewis/Fisher-344 rats were used as donors/recipients. ...
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