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Results 451 - 500 of 615
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Sastre J - - 1987
We describe a patient with pulmonary ceroid histiocytosis. Skin pigmentation, chest x-ray film and laboratory findings were normal. Only pulmonary function tests were abnormal (TLC = 63 percent, DLco = 52 percent). Based on these functional data, the patient was submitted to a lung biopsy by thoracotomy. Brown pigmented histiocytes ...
Stentoft J - - 1987
A 26-year-old woman with extra-pulmonary Wegener's granulomatosis was treated with cyclophosphamide for 3.25 years, cumulated dose of 91 g. Six months before cessation of therapy discrete radiological signs of apical fibrosis appeared. The changes were progressive regardless of discontinuation of cyclophosphamide and led to severe restrictive ventilatory defect.
Ofner S - - 1987
We evaluated the effect of betaxolol on the pulmonary function tests of nine patients with glaucoma and chronic obstructive pulmonary disease (COPD) requiring beta-blocker therapy. The results of pre-treatment pulmonary function tests were compared to results after two weeks of betaxolol therapy. The mean ratio of forced expiratory volume in ...
Westcott J L - - 1986
Postmortem examination of the lungs of 12 patients with end-stage pulmonary fibrosis revealed the frequent (nine of 12) presence of bronchiectasis. The segmental and subsegmental bronchi were dilated, tortuous, and had a convoluted appearance that resembled a string of pearls. Bronchiectasis was confined to areas of advanced fibrosis. When fibrosis ...
Maharaj B - - 1986
An indian woman with pulmonary alveolar proteinosis whose symptoms, chest radiograph and pulmonary function tests remain unchanged 3 years after diagnosis is described. A brief discussion of this rare disease is also presented.
Gonzalez-Rothi R J - - 1986
To investigate the function of alveolar macrophages (AM) and the mechanisms of impairment in pulmonary alveolar proteinosis, we established in culture AM from three patients and from eight normal nonsmokers and assessed phagocytosis and phagolysosome fusion by the acridine orange assay with live yeast as the phagocytic challenge. Alveolar macrophages ...
Porterfield J K - - 1986
Neurofibromatosis von Recklinghausen (NFvR) has been reported to be associated with diffuse interstitial pulmonary fibrosis. We describe a patient with NFvR presenting in middle age with dyspnea and cyanosis. Chest radiographs showed right ventricular enlargement, dilated proximal pulmonary arteries, and bilaterally increased interstitial markings. Cardiac catheterization showed moderately severe pulmonary ...
Munro J M - - 1986
Retroperitoneal fibrosis is associated with Riedel's thyroiditis, in which an unexpectedly high proportion of the plasma cells have been reported to contain IgA and lambda light chains. It has been suggested that retroperitoneal fibrosis and the inflammation and fibrosis in thick-walled abdominal aortic aneurysms are caused by a hypersensitivity reaction ...
Berry D - - 1986
We used the model of bilateral cervical vagotomy of adult rabbits to cause respiratory failure characterized by pulmonary edema, decreased lung compliance, and atelectasis. We documented an 18-fold increase in radiolabeled albumin leak from the vascular space into alveolar washes of vagotomy vs. sham-operated rabbits (P less than 0.01). Despite ...
Skyberg K - - 1986
Twenty-five cable plant workers exposed to mists and vapors of mineral oils and kerosene for 5-35 years have been investigated in a cross-sectional, matched pairs study. The exposed cohort and the referents were examined by radiology, pulmonary function measurements, and a questionnaire for symptoms of respiratory disease. Lung tissue from ...
Dineen M K - - 1986
Bleomycin has become an important component of combination chemotherapy, particularly in the treatment of metastatic testis carcinoma. Pulmonary toxicity is a major risk and irreversible pulmonary fibrosis or even death may result from its use. Rarely diffuse fibrosis may lead to discrete nodularity mimicking pulmonary metastasis. We report such a ...
Malconian,Mark K.
The relationship between alveolar P02 and PC02 at altitudes up to the summit of Mt. Everest (barometric pressure (Pb) =240 torr) has been investigated in a small number of individuals during mountaineering expeditions and one hypobaric chamber study. No previous study has measured these values on the same subjects throughout ...
Cooke C T - - 1986
We report a case of pulmonary asbestosis in a patient who also developed glomerulonephritis and lymphomatoid granulomatosis. The pulmonary reaction was unusual, characterized clinically by an acute onset of symptoms after a prolonged latent period and morphologically by an interstitial pneumonitis with prominent desquamative features and a paucity of fibrosis. ...
Pitts-Tucker T J - - 1986
Finger clubbing was measured in 73 of 105 patients with cystic fibrosis undergoing full assessment. The sign correlated well with the chest x ray score and indices of pulmonary function and infection but not with weight, height, age, liver function, or degree of fat malabsorption. The presence of clubbing suggests ...
Packe G E - - 1986
The ventricular weights in 43 patients with interstitial pulmonary fibrosis were retrospectively compared with those in 172 patients with emphysema and chronic bronchitis. The mean right ventricular weight of patients with interstitial pulmonary fibrosis and those with emphysema and chronic bronchitis was 85.5 g (SD 23.2) and 88.8 g (34.3), ...
Bitterman P B - - 1986
We evaluated 17 clinically unaffected members of three families with an autosomal dominant form of idiopathic pulmonary fibrosis for evidence of alveolar inflammation. Each person in the study was examined by gallium-67 scanning for a general estimate of pulmonary inflammation, and by bronchoalveolar lavage for characterization of the types of ...
Yu S H - - 1986
Lipid extracts of bovine pulmonary surfactant containing the 6 kDa apoprotein, but lacking the 35 kDa apoprotein, can mimic the essential characteristics of pulmonary surfactant on a pulsating-bubble surfactometer. Reconstituted surfactant can be produced by combining silicic acid fractions containing 6 kDa apoprotein and phosphatidylglycerol with phosphatidylcholine. Treatment of the ...
Davidson B L - - 1986
There is conflicting and incomplete information in the literature on the pulmonary reaction which can occur following treatment of schistosomiasis. We examined the pulmonary function, bronchoalveolar lavage profile, and lung histopathology of a patient with pneumonia and peripheral eosinophilia following oxaminquine chemotherapy for intestinal Schistosoma mansoni infection. Spirometry revealed restrictive ...
Jacobsen L E - - 1986
In patients with cystic fibrosis, plain chest radiographs may suggest the presence of bronchiectasis, bronchoceles, hilar adenopathy, or pulmonary arterial hypertension. We compared computed tomography (CT) with conventional chest radiography in 12 patients. CT clearly reveals the cause of increased linear markings, nodular lesions, and enlarged hila as seen on ...
Yoshimura H - - 1986
High-resolution computed tomographic scans of 19 patients with pulmonary asbestosis revealed a subpleural curvilinear shadow (SCLS) parallel to the inner chest wall in the lungs of 15 (78.9%) patients. Most (46.7%) SCLS measured greater than 5 cm but less than 10 cm in length and occurred less than 1 cm ...
Lyons D J - - 1986
Ethanol is claimed to have a specific damaging effect on the lung and to be at least partially responsible for pulmonary dysfunction in alcoholics. Adequate allowance for the damaging effects of cigarette smoking has not, however, been made hitherto. Pulmonary function studies were undertaken in 27 alcoholic subjects. Although there ...
Basset F - - 1986
The histopathologic and ultrastructural features of intraluminal organizing and fibrotic changes were studied in open lung biopsies and autopsy specimens from 373 patients with interstitial lung disorders, including hypersensitivity pneumonitis (n = 44), idiopathic pulmonary fibrosis (n = 92), collagen-vascular diseases (n = 20), chronic eosinophilic pneumonia (n = 10), ...
Holden W E - - 1986
In this report we describe a young woman with idiopathic thoracic scoliosis associated with marked lordosis. Pulmonary function, tested in the upright standing position, showed a restrictive pattern of impairment. However, when the patient was tested in the forward-flexed position, pulmonary function was dramatically improved. Following surgical partial correction of ...
Cazzadori A - - 1986
A patient with atrial premature depolarizations developed pulmonary toxicity during long-term treatment with amiodarone. The clinical features were cough and dyspnea. Pulmonary function tests showed a restrictive defect and severe impairment of gas transfer. Diffuse interstitial and intra-alveolar shadows were noted on chest X-ray. Lung specimens obtained by transbronchial biopsy ...
Poirot G - - 1986
Based on the dissection of 30 hemi-mandibles, the authors report a study of the inferior alveolar artery in its intraosseous course. On morphologic considerations they propose a classification of the collaterals into two groups: the principal collaterals destined for the teeth and the bony alveolar tissue and the secondary collaterals ...
Lilis R - - 1986
A cohort of 1,117 asbestos insulation workers was established in 1963 and has been prospectively followed since then. Chest X-ray abnormalities detected at the initial medical examination, and interpreted according to the International Labour Office Classification of Radiographs of Pneumoconioses are reported in this paper. The prevalence of all radiographic ...
Neukirch F E - - 1985
Epidemiologists using pulmonary function tests agree that a number of factors have to be taken into account. In a study carried out among 912 men aged 22 to 54 we found that those having a common cold and cough on the day of examination had lower pulmonary function values. So ...
Tuder R M - - 1985
Lungs of twelve patients with chronic paracoccidioidomycosis (Pb) were studied in an attempt to understand the pathogenesis of the pulmonary disease. Ribbons of the lung parenchyma including the hilar region and directed towards apical, basal and lateral regions were subdivided into sections from the hilar, intermediate and peripheral segments. The ...
Fischbein A - - 1985
Interstitial pulmonary fibrosis (IPF) is often of uncertain etiology and is therefore named 'idiopathic' pulmonary fibrosis. Some occupational exposures, however, are known to cause interstitial fibrosis, asbestos and silica being well-known examples. We present clinical and pathological findings of a case with IPF and the results of microchemical analysis of ...
Lilis R - - 1985
This report describes a patient who developed acute chemical pneumonitis following overexposure to metal mercury vapor. The exposure occurred in a gold extraction facility where a gold-mercury amalgam was heated in a confined area. Prompt treatment with penicillamine and corticosteroids was instituted; radiologic pulmonary infiltrates disappeared within a week, but ...
Tablan O C - - 1985
An unusual case of chronic interstitial fibrosis that developed as a sequela of Mycoplasma pneumoniae pneumonia is described. Predominant manifestations included progressive exertional dyspnea, shortness of breath, persisting lung infiltrates, low lung volumes, and low pulmonary diffusing capacity. Open lung biopsy one year after the acute stage of mycoplasma pneumonia ...
Galko B - - 1985
The association between digital clubbing and idiopathic pulmonary fibrosis has been well established; however, the simultaneous occurrence of hypertrophic pulmonary osteoarthropathy and interstitial fibrosis, in the absence of neoplastic disease, has only been described in two case reports and was not mentioned in any of 336 patients described in several ...
Regadera J - - 1985
Autopsy specimens of the testes, epididymides, and spermatic cords from 20 adult young and 60 elderly men were studied by angiographic and histologic techniques. Testicular alterations in elderly men were correlated to the degree of aortic atheromatosis. Elderly men without manifest atheromatosis showed no lesions. Elderly men with slight atheromatosis ...
Ludwig P W - - 1985
The polymorphonuclear leukocyte (PMN) may play an important role in the pathogenesis of emphysema. Cigarette smoking is associated with the accumulation of PMN in the lung as determined by bronchoalveolar lavage. We enumerated alveolar wall PMN on histologic sections from lungs of humans and hamsters with and without cigarette smoke ...
Hasleton P S - - 1985
A series of 20 cases of radiation bowel disease (RBD) was studied qualitatively and the arterial changes were studied quantitatively. A control series of 45 cases was studied. In the control cases there were positive correlations between the medial thickness of all vessels studied and the diastolic blood pressure as ...
Cohn J R - - 1985
A patient with longstanding mild asthma presented with a several month history of almost continuous wheezing. Pulmonary function tests suggested large airway variable intrathoracic obstruction. At bronchoscopy, she was found to have severe bronchomalacia limited to the left main bronchus. There was almost complete obstruction of that airway during forced ...
Munakata M - - 1985
Pulmonary auscultation, pulmonary function tests and radiological examination were done in 127 hospitalized patients with silicosis. Fine crackle (FC) was heard in 21.3% of patients, coarse crackle (CC) in 28.5%, rhonchi or wheeze (RorW) in 25.2% and friction rub (FR) in 5.5%. In complicated silicosis the incidence of rales was ...
Wilson E R - - 1985
A 6 3/4-year-old boy with neuronopathic Gaucher's disease died unexpectedly. Autopsy demonstrated unusual vascular findings with the presence of Gaucher's cells and intimal-medial fibrosis in the ascending aorta and widespread acute hemorrhagic necrosis of the left ventricular myocardium. The combination of eccentric, intimal fibrosis of coronary arteries, left ventricular hypertrophy, ...
Renne R A - - 1985
As a first step in the development of an animal model for determining the role of pulmonary fibrosis in the etiology and pathogenesis of lung cancer, the fibrogenic potential of quartz, quartz and ferric oxide administered together, fibrous glass, and hydrated alumina were studied by multiple intratracheal instillation in groups ...
Singh S - - 1984
Continuous ambulatory peritoneal dialysis (CAPD) produces a nearly continuous state of iatrogenic ascites which may interfere with respiratory excursions of the diaphragm and compromise ventilatory function. Sitting and supine studies of pulmonary function and arterial blood gas analyses done serially in 13 patients undergoing CAPD showed a significant decline in ...
Benjamin R G - - 1984
Pulmonary function testing provides an important insight into the pathophysiology in patients with sarcoidosis. Major functional abnormalities in this disease include decreased diffusing capacity, lung compliance and lung volumes. Arterial oxygen desaturation with exercise is common. Airways obstruction may occur as an isolated finding or be superimposed on the interstitial ...
Desmond K J - - 1984
To assess whether it would be possible to avoid repeated arterial blood sampling in children with cystic fibrosis, the relation between the forced expiratory flow at 25% to 75% of the vital capacity (FEF25%-75%) and the partial pressure of arterial oxygen (PaO2) was examined. The PaO2 and the logarithm of ...
Weiss W - - 1984
The long-term inhalation of cigarette smoke is associated with the appearance of diffuse small irregular opacities of mild profusion on chest roentogenograms of some subjects in a limited number of reports. Human histologic and experimental animal studies have shown the presence of pulmonary interstitial fibrosis. The radiographic abnormalities may be ...
Glassroth J L - - 1984
The development of interstitial pulmonary fibrosis (IPF) is associated with persistent cellular infiltration and progressive connective tissue accumulation in the alveolar walls. To develop and characterize an animal model of IPF in which pulmonary fibrosis evolves slowly, as well as to develop an inexpensive, easily produced, model of asbestosis, Syrian ...
Oghiso Y - - 1984
Although all commercial types of asbestos can cause pulmonary fibrosis, little is known about ultrastructural differences in the evolution of pulmonary lesions induced by amphiboles and serpentines. The present study was designed to compare the histological and ultrastructural effects produced by chronic inhalation of either crocidolite (amphibole) or chrysotile (serpentine) ...
Essop A R - - 1984
The pulmonary manifestations of sarcoidosis are varied. This report describes a patient with rapidly progressive pulmonary sarcoidosis which had several unusual features and presented with acute pneumonia with air bronchograms on chest radiographs. Gallium-67 scanning and serum angiotensin-converting enzyme estimations aided in the diagnosis and in determining the response to ...
Peters-Golden M - - 1984
The course of functional pulmonary involvement in systemic sclerosis remains controversial; and it is not known if specific clinical or demographic features are predictive of subsequent changes in pulmonary function. To address these questions, we conducted a non-concurrent prospective study of serial pulmonary function in 24 patients with systemic sclerosis ...
Lakhera S C - - 1984
Studies were conducted to evaluate pulmonary functions in Indian athletes and sportsmen associated with different athletic events and games. It was found that swimmers were having significantly higher vital capacity (VC) and forced expiratory volume (FEV1) values than all other athletic groups studied. Results have been discussed keeping in view ...
Mitchinson M J - - 1984
A review of the histology of atherosclerotic aneurysms shows that all are accompanied by adventitial inflammation and fibrosis, usually slight. Severe degrees of this periaortic inflammation are visible macroscopically and give rise to the conditions variously known as inflammatory aneurysm or perianeurysmal retroperitoneal fibrosis. The disease appears identical to most ...
Beckman G - - 1984
Pulmonary function was studied in thirteen individuals heterozygous for the alpha 1-antitrypsin allele PiF. Respiratory symptoms were present in seven out of twelve individuals with the FM phenotype, of which five had pulmonary function impairment, mostly of the obstructive type. One patient with the phenotype FZ had bronchitic symptoms and ...
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