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Results 301 - 350 of 363
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Förstermann U - - 1983
6-keto-PGE1, when injected intravenously (i.v.) or into the aortic arch of cats, produced similar dose-dependent decreases in mean arterial blood pressure. The hypotensive effect of PGI2 was slightly less pronounced compared with that of 6-keto-PGE1, but was equally potent after i.v. and intra-arterial administration. PGE2 had a more potent depressor ...
Luursema P B - - 1983
To study subclinical pulmonary toxicity of bleomycin we measured the single-breath carbon monoxide transfer factor (TLCO) and its components, pulmonary capillary blood volume (Vc), diffusing capacity of the alveolar-capillary membrane (Dm), and vital capacity (VC) in a homogenous group of 18 patients with testicular nonseminomatous germ cell tumor treated with ...
Cartwright T R - - 1983
Rapidly progressive bilateral pulmonary infiltrates occurred in a 19-year-old man following an unusual hydrocarbon abuse. The acute illness was the result of a "trick" known as "fire-breathing." Fire-breathing involves filling the oral cavity with butane gas, from an ordinary butane cigarette/cigar lighter, and exhalation of the volatile vapors over an ...
Rakita L - - 1983
Of the side effects that complicate amiodarone therapy, pulmonary fibrosis is potentially the most serious. Therefore, the development of techniques to predict the onset of this troublesome reaction would be of great practical value. Reports of 39 patients who developed pulmonary toxicity with amiodarone were evaluated for clues to precipitating ...
Milner L S - - 1983
Five children between the ages of 6 and 15 years, who required chronic hemodialysis (HD) for renal failure, were studied to evaluate the central and pulmonary effects of HD on gas exchange. Acetate dialysate was used, and dialysate pO2 and pCO2, arterial pO2 and pCO2, endtidal CO2 and minute ventilation ...
Midtgård U - - 1983
A morphometric analysis has been made of the rete ophthalmicum which is a functional arteriovenous heat exchange system in the heads of birds. The morphological data were obtained from histological sections of the rete from 40 species of birds covering a weight range of 20,000-fold. The maximal number of retial ...
Krantz P - - 1983
Determination of the exact cause of death in diving casualties is usually difficult at autopsy. In such cases, formation of gas in various organs is sometimes supposed to be causative, and thus establishment of the exact distribution of gas is crucial. This is not possible by conventional autopsy techniques. In ...
Amenta F - - 1983
The cholinergic innervation of the pulmonary circulation was studied in man. Both extra- and intrapulmonary branches of the pulmonary artery and vein are provided with a cholinergic of the vein. In the main branches of the pulmonary vessels, the existence of two nerve plexuses, a superficial and a deep one, ...
Bull C - - 1983
In order to study the usefulness of incorporating a subpulmonary ventricular chamber (SPVC) in the Fontan circulation, we compared the hemodynamics of 18 patients who underwent an atriopulmonary connection with those of 17 patients with an atrioventricular connection. Early postoperatively, regardless of whether an SPVC was incorporated or not, the ...
Astry C L - - 1983
Inhalation exposure to acrolein induced a dose-dependent impairment of pulmonary antibacterial defenses in mice. Animals exposed to 3 or 6 ppm of acrolein were increasingly less effective in inactivation of aerogenic challenges of 32P-labeled Staphylococcus aureus. Acrolein concentrations greater than 6 ppm caused increased sensory irritations, but no additional impairment ...
Beatty P - - 1982
A versatile closed circuit with new features is described. It may be used in a totally closed manner, without continuous gas inflow. As gas is absorbed from the circuit, it is replaced through a demand valve. Facilities for continuous gas input and use of a ventilator are included, and one ...
Sheldon M I - - 1982
To determine whether there is a pulmonary chemoreceptor for CO2 that influences spontaneous ventilation (VE), we separated the systemic and pulmonary circulations and controlled partial pressure of CO2 (PCO2) independently in each circuit under hyperoxic conditions and measured VE. Dogs were anesthetized with ketamine and maintained with 1% halothane. Systemic ...
Pásztor E - - 1982
In a case of consecutive occlusion of both internal carotid arteries bilateral STA-MCA anastomoses were established. Since a series of angiographic examinations were undertaken, dynamics and probable efficacy of both natural and artificial collateral circulations could be followed up in a two-year period. Objectively in the evaluation of anastomoses was ...
Jobst M - - 1982
Using labeled albumin, the permeability index was determined for the aorta and other arteries of the rabbit after different circulation times. The results were reproducible. Different indices of permeability were obtained for different arteries. When the circulation time of the tracer was extended, the increase in the permeability index was ...
Schuster D P - - 1981
High-frequency jet ventilation (HFJV) was used during the treatment of fulminant pulmonary edema in a 45-year-old man so that toxic levels of oxygen could be avoided when conventional methods of ventilation in combination with high levels of PEEP (20 cm H2O) were unsuccessful in raising PaO2. On each of four ...
Teates C D - - 1981
The hospitals and departmental records of the University of Virginia Medical Center from 1976 to 1980 show an increasing frequency of ventilation studies relative to perfusion studies and a decrease in frequency of ventilation-perfusion diagnosis of pulmonary embolus. Pulmonary angiograms have increased from one per 68 nuclear studies to one ...
Kuriyama T - - 1981
We propose that the pulmonary hypertension developed by cattle and swine at high altitude is associated with their lack of collateral ventilation. We reason that if collateral ventilation helps keep interregional oxygen tensions homogeneous, then in its absence, local ventilation-perfusion balance must rely on arterial constriction; the additional work causes ...
Chermet J - - 1981
The author describes a simple technique for arteriography of lower limbs with blocked circulation. Through either an antegrade or retrograde femoral approach, a balloon catheter with a double lumen is inserted and used to produce an arterial occlusion. Arteriography is then performed. With this technique, small peripheral thrombi can be ...
Edlund A - - 1981
The pulmonary formation of prostacyclin (PGI2), as reflected by the difference in concentration of pulmonary and systemic arterial radioimmunoassayed 6-keto-PGF1 alpha, was determined in six healthy waking subjects. The systemic arterial 6-keto-PGF1 alpha levels were low (less than or equal to 50 pg/ml), and no evidence of pulmonary formation and ...
Robinson N E - - 1981
Lobar differences in the mechanics of collateral ventilation were investigated in sublobar segments of intact dog lungs using a wedged-catheter technique. At functional residual capacity, the collateral time constant was longest in the left upper lobe and shortest in the lower lobes, with the remaining lobes having intermediate values. The ...
Suter P M - - 1981
Continuous positive airway pressure (CPAP) is used frequently to improve gas exchange in acute pulmonary failure. We investigated clinical and respiratory variables in 98 patients presenting with two or more of the classical criteria for endotracheal intubation and mechanical ventilation. CPAP applied by a face mask was efficient in 60 ...
Goris M L - - 1981
The value of ventilation studies in conjunction with pulmonary perfusion scintigraphies for the diagnosis of pulmonary emboli is reviewed. A retrospective study of 273 consecutive cases and comparison with 42 angiographic results provides the data base. The data are compared with previously reported results and confirm the diagnostic gain obtained ...
Patterson R W - - 1981
With measured values of arterial blood gas tensions, of expired respiratory gas fractions, and volume of the expired ventilation, the determinants of alveolar oxygen tension (PAO2) were used to evaluate their influence on the development of the arterial hypoxemia that occurs in spontaneously breathing patients undergoing hemodialysis using an acetate ...
Miller J N - - 1981
Despite the seriousness of pulmonary O2 toxicity, patients can generally withstand 1 atm. of PO2 for at least 24 hours. Also, there is no evidence that clinically relevant pulmonary O2 toxicity occurs in humans at inspired partial pressures below 0.4 to 0.5 ATA, even with prolonged exposures. Neither is there ...
Moutinho M E - - 1981
A 7-month-old girl succumbed to respiratory failure following exposure to high-density mercury vapor produced by heating of the metal in the home. Her course typified inhalation mercury toxic reaction, which in its focus on pulmonary damage creates a clinical picture distinct from that of chronic and oral mercury poisoning.
Sordillo E M - - 1981
A case of pulmonary toxicity after chlorozotocin (DCNU) is described. This patient developed shortness of breath, nonproductive cough, and interstitial infiltrates after his third dose of DCNU. This was documented on pulmonary function tests which showed a reduction in vital capacity and pulmonary diffusion capacity. Similar findings have been reported ...
Hallman M - - 1980
The phospholipids of tracheal aspirates in persistence of the fetal circulation (PFC) were compared to those in the respiratory distress syndrome (RDS) and those in other severe diseases of the newborn. The infants with PFC were hypoxemic despite 80 to 100% inspiratory oxygen. There were small, if any, pulmonary parenchymal ...
Alderson P O - - 1980
Radioactive gases are useful for evaluating pulmonary ventilation because they allow assessment of regional lung function in a physiologic, noninvasive manner. The most widely used radioactive gases are Xe-133, Xe-127, and Kr-81m. These gases provide visual and/or quantitative assessments of regional ventilation or ventilation-perfusion matching in obstructive airways disease, and ...
Bhanot S C - - 1980
As urologic surgery becomes more extensive planned or inadvertent compromise of the vascular supply of the bowel becomes more likely. Familiarity with the normal anatomy of the vascular supply of the large and small intestines must, therefore, be part of every urologist's fund of knowledge. With an appreciation of the ...
Matsen F A FA - - 1980
In animal and human investigations, transcutaneous PO2 proved to be a sensitive and rapid indicator of the patency of the artery and veins supplying a limb part. Furthermore, transcutaneous PO2 indicated the presence or absence of collateral circulation. Commercially available transcutaneous PO2 probes were easily applied to human fingers and ...
Derks C M - - 1980
In this paper, the distribution of ventilation (VA) and of pulmonary perfusion (Q), gas exchanges, and the single breath CO diffusing capacity are measured in 8 dogs before and after left pneumonectomy. During surgery 4 dogs, in which the left pulmonary artery is clamped, and 4 other dogs in which ...
Hietala S O - - 1979
The abdominal angiograms of 381 patients were critically reexamined for the existence of collateral circulation in cases of renal artery stenosis or occlusion. Typical renal artery stenosis was found in 39 patients; among these, 17 had a collateral circulation, which was extrarenal in 15 and intrarenal in two. Collateral circulation ...
Hansen-Leth C - - 1979
With the aid of microangiography the vascularization in the amputation stumps of 108 rabbits was studied, both in extremities with normal circulation and in those supplied with collaterals. It was found that the vascularization of the normal leg was altered by amputation, with the development of newly-formed, pathological, spirally-twisted vessels. ...
Lock J E - - 1979
6-Keto-PGE1 is a potent direct dilator of the pulmonary and systemic circulations of the newborn lamb under both normoxic and hypoxic conditions. Its threshold dose is similar to that of PGI2 and PGE1. Under hypoxia, 6-keto-PGE1 appears equally effective on the pulmonary and systemic circulations, while under normoxia it predominantly ...
Cassin S - - 1979
Effects of prostaglandins of the E series and their metabolites on pulmonary and systemic circulations of newborn and exteriorized fetal goats (anesthetized with chloralose) were evaluated in situ using an isolated perfused left lung lobe preparation. Prostaglandin E1 (PGE1) and, to a lesser extent, prostaglandin E2 (PGE2) infusions resulted in ...
van der Steen A - - 1979
Various types of collateral circulation and of intra- and extracerebral stealmechanisms have been described during the past two decades. The object of this short report is to discuss the clinical-angiographic data of two patients with extracranial cerebro-vascular occlusion, also in relation with current literature. Two case histories are described. The ...
Hlastala M P - - 1979
Bubbles of either He, N2 or SF6 were infused intravenously into anesthetized dogs at a rate of 0.2 ml/kg/min. Alterations in pulmonary gas exchange were quantitated by the invert gas elimination method during control, steady state infusion and resolution phases. The hypoxemia produced was predominantly due to regions of low ...
Kiil J - - 1979
In 34 patients with suggested pulmonary emboli, ventilation scintigraphy with 133Xe and perfusion scintigraphy with 99Tcm-labelled albumin spheres were carried out. The combined ventilation-perfusion scintigraphy had a significantly higher diagnostic specificity (1.0, confidence limit 0.69-1.0) than perfusion scintigraphy alone (0.48, 0.26-0.70). Both methods had a diagnostic sensitivity of 1.0.
Uflacker R - - 1978
The changes in coronary collateral circulation after bypass surgery were analyzed in 50 patients with coronary disease. The demonstration of collateral circulation was found to be dependent upon the severity of the coronary heart disease and the patency of the bypass. When the graft was patent, it was usually not ...
Lechner A J - - 1978
This report has reexamined the relationship between standard and maximal rates of oxygen consumption (VO2std and VO2max) and pulmonary surface area in mammals whose weights extend over the lower half of the total log weight range in mammals. For combined groups of wild and laboratory animals with body weights of ...
Brown W G - - 1978
The use of bleomycin sulfate as an antineoplastic agent has been limited by its substantial pulmonary toxic effects. The exact incidence and prognosis of bleomycin-pneumonitis is unresolved. Although bleomycin pulmonary toxicity is thought to be dose-related, recent reports have emphasized severe reactions at low doses. Furthermore, severe pulmonary toxicity has ...
Ekeland A - - 1978
Physiologic saline, meglumine metrizoate (Isopaque) and metrizamide (Amipaque) were injected into the ear artery of Wedder rabbits. The effect on the microcirculation in previously inserted ear chambers was recorded by cinematography. Following injection of the contrast media, the circulation was slow, followed by a phase with arteriolo-venular shunting and poor ...
Green M R - - 1977
Pulmonary parenchymal or pleural reactions to chemotherapeutic agents used in the management of patients with malignant diseases are being recognized with increasing frequency. Alkylating agents, asparaginase, bleomycin, methotrexate and procarbazine have all been implicated. Some of the reactions, such as the rare procarbazine pleuritis and pneumonitis, represent hypersensitivity phenomena. Others, ...
Rodbard S - - 1977
Ventilation of an isolated lung lobe modifies the rate of inflow into its pulmonary artery (Murao and Rodbard, 1971). The present studies show that ventilation also influences the rate of outflow from the pulmonary vein in a manner which differs significantly from the effects on the rate of inflow into ...
Verstappen F T - - 1977
In mongrel dogs weighing 15--25 kg and anesthetized with thiopental-gamma-hydroxybutyric acid the effects of venous gas infusion and injection on several respiratory variables were investigated. During spontaneous respiration pulmonary gas embolism caused an increase of the ventilatory minute volume depending on the degree of embolization. The contribution of breathing frequency ...
Boutros A R - - 1977
An algorithm for management of pulmonary complications in burn patients on the same basis as in patients with adult respiratory distress syndrome is outline. Pao2 of less than 60 torr (F(I)O2 0.21-0.4, PaCO2 over 40 torr, pH less than 7.35, respiratory rate over 40/min, and clinical evidence of compromised upper ...
Worth H - - 1976
To study the influence of physical properties of the respired gas on alveolar gas exchange, alveolar-arterial partial pressure differences for O2 and CO2 were measured in anesthetized dogs that were artificially ventilated with gas mixtures of O2 in N2, He, Ar or SF6. In both hyposia and normoxia alveolar-arterial PO2 ...
Klein L - - 1976
Bone from rats sacrified at 2, 5, and 95 weeks of age following 45Ca and 3H-tetracycline labeling in utero or postnatally was placed in solutions of physiological saline, nonradioactive calcium, or tetracycline. This procedure was designed to determine the availability for exchange of 45Ca and 3H-tetracycline from bone mineral in ...
Bishop R L - - 1976
Arterial pH, Pco2, and osmolality were determined serially during cardiac resuscitation in patients and in dogs, with and without administration of sodium bicarbonate. These studies demonstrate that (1) in the absence of preexisting acidosis, severe acidosis can be prevented by adequate ventilation alone; (2) sodium bicarbonate administration results in a ...
Flynn J T - - 1976
Arterial plasma concentrations of PGF2alpha and 15-keto-PGF2alpha were determined in sham shock and splanchnic artery occlusion shock dogs. Arterial PGF2alpha concentrations (expressed as percentage of control) increased significantly in the SAO group when compared to the sham group during postrelease sampling periods. Similarly, 15-keto-PGF2alpha, a major metabolite of PGF2alpha also ...
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