Heart rates (HR) were measured before (control HR) and after (ischemic HR) balloon inflation during percutaneous transluminal coronary angioplasty in 96 patients with effort angina pectoris. The delta HR, defined as (ischemic HR-control HR), in the right coronary artery occlusion was significantly smaller than that in the left anterior descending ...

Percutaneous intentional extraluminal recanalisation (PIER) of the femoropopliteal artery is a new catheter technique to overcome long chronic occlusions. This technique was applied to 40 long chronic occlusions of the femoropopliteal segment. The mean length of the superficial femoral artery (SEA) occlusions was 16.9 cm, the mean length of the ...

Autonomic mechanisms may have an important role in the clinical presentation of acute coronary occlusion. This research was designed to evaluate the effect of preocclusion stenosis severity on the immediate autonomic heart rate (HR) responses to a subsequent acute occlusion of the coronary artery. HR and its variability in the ...

Arterial occlusion using radiofrequency energy was performed. The length of the noninsulated part of the guidewire was 10 mm and the duration of radiofrequency supply was 20 s. Animal experiments were carried out in 17 canine arteries; 4 out of 6 arteries less than 2.3 mm in diameter were completely ...

Temporary intracranial arterial occlusion is often utilized during the surgical treatment of intracranial aneurysms. Although numerous experimental studies have suggested that repetitive, brief periods of global ischemia cause more severe cerebral injury than a similar single period of global ischemia, this issue has not been extensively studied in relation to ...

Electrocardiograms were recorded in conscious pigs during psychological stress (touching), left anterior descending coronary artery occlusion, intracerebral levopropranolol (0.05 mg/kg), and their respective controls. The R-R intervals were evaluated with both a deterministic measure (point correlation dimension) and a stochastic one (mean). Only the deterministic measure was sensitive to between-subject ...

The occurrence of unexplained, rapidly recurring occlusions of arteries and veins in a previously healthy young woman is described. Post mortem examination showed no macroscopic abnormalities but revealed microscopic metastatic adenocarcinoma with remarkable intravascular localisation of the malignant cells. Whereas highly sensitive markers for the existence of systemic activation of ...

Canine models of autologous PE and balloon occlusion of the pulmonary vasculature were used to evaluate radioaerosol deposition and to quantify radioaerosol clearance in the immediate postembolic period. METHODS: A total of 28 animals were anesthetized, intubated and studied (central balloon occlusion = 4, peripheral balloon occlusion = 7, autologous ...

A thin myocardial layer adjacent to the epicardium (epicardial rim) often survives after transmural myocardial infarction. Regional myocardial blood flow (Qm) at this rim may be high enough to maintain myocardial viability during coronary occlusion. To test this hypothesis, we measured Qm in 12 anesthetized dogs during left anterior descending ...

The survival of tissues distal to major arterial occlusions is critically dependent on the development of collateral blood vessels. The biochemical events fundamental to their evolution remain undefined. To determine the role of endogenous basic fibroblast growth factor in the development of the collateral circulation we evaluated the dose response ...

The goal of this prospective study of the piezoelectric pulse sensor device was to determine its technical applications and its ability to detect lower extremity occlusive arterial disease. Ten extremities (five volunteers) were evaluated to assess the ability to place the sensor in the correct anatomic position on a foot ...

99Tcm-hexamethylpropyleneamine oxime (99Tcm-HMPAO) single photon emission computed tomographic (SPECT) brain imaging performed in conjunction with balloon test occlusion of the carotid artery has been used to assess risk of neurologic sequelae that might follow permanent surgical ligation of the artery. The predictive value of cortical hypoperfusion during temporary carotid occlusion ...

Temporary occlusion of an intracranial artery is frequently necessary in the surgical management of intracranial aneurysms, arteriovenous malformations, and tumors. While the risks of vessel damage associated with clip application have been lessened by improved design, the threat of ischemic damage remains. It is unclear whether multiple, brief periods of ...

PURPOSE: To evaluate the effectiveness of a new vascular occlusion device. MATERIALS AND METHODS: The device was created by coating a balloon-expandable stent with a silicone sleeve that tapers to a blind-ended nozzle at its leading end. Once crimp-mounted on an angioplasty balloon catheter, the device is introduced over a ...

A low speed rotational catheter system (ROTACS) was used to recanalize total occlusions of the femoropopliteal artery in two patient groups. In Group A, previous attempts to recanalize the occlusions using standard guidewires and catheters had failed. Group B had undergone no previous attempts at recanalization. The ROTACS was successful ...

Aortic aneurysms are characterized by the destruction of the extracellular matrix of the media, whereas occlusive disease involves excess matrix accumulation within the intima. Plasmin degrades extracellular matrix directly and indirectly by activation of latent metalloenzymes. To determine the expression of tissue- and urokinase-type plasminogen activators, immunoassay, fibrin autography, Northern ...

Middle cerebral artery (MCA) occlusion in halothane-anesthetized rats induced the zinc finger gene, NGFI-A, in brain. In situ hybridization studies showed that NGFI-A was induced throughout all of the cortex following MCA occlusion. By 24 h after MCA occlusion there was little expression of NGFI-A mRNA in the core of ...

Nine Yorkshire pigs underwent coronary artery occlusion followed by 2 hours of reperfusion. In five pigs (group A) the occlusion time was 15 minutes and in four pigs (group B) the occlusion time was 1 hour. Teboroxime was administered and images were acquired at baseline, and following occlusion and reperfusion. ...

Penile revascularization via inferior epigastric dorsal penile artery bypass is a treatment option for men with vasculogenic impotence due to proximal segmental arterial occlusion. Various diagnostic tests have been used to identify arterial vascular disease but pudendal arteriography remains the gold standard anatomical study. Unfortunately, more than 80% of impotent ...

We investigated to determine the time limits for intestinal ischemia and congestion. The experimental models were produced by clamping both ends and the intended feeder vessels of an approximately 1-cm length of rat jejunum. The results showed that in arteriovenous occlusion, the time required for the recovery rate to reach ...

The technique of subintimal angioplasty has been attempted on 200 consecutive femoropopliteal artery occlusions of median (range) length 11 (2-37) cm. The principle of the technique is to traverse the occlusion in the subintimal plane and recanalise by inflating the angioplasty balloon within the subintimal space. The technical success rate ...

Thrombotic occlusion of the left common iliac artery occurred in a 59-year-old man after an anterior and posterior spinal fusion. Preoperatively, the patient was known to have peripheral vascular disease. Symptoms of an L4-5 radiculopathy were noted postoperatively. After an iliac-iliac bypass, the symptoms completely resolved. Retraction of the vessels ...

The purpose of this study was to examine mechanisms involved in the response of native collaterals to coronary occlusion. In anesthetized dogs native collaterals were identified as vessels coursing between the left anterior descending and left circumflex arteries using fluorescence angiography. After a left anterior descending occlusion in 12 dogs, ...

Intermittent occlusion of the ulnar artery developed in a patient causing cramp in her right hand. Both flexion and extension of the wrist completely obstructed bloodflow in the ulnar artery, at a level just proximal to the wrist. At operation, a tight band of antebrachial fascia was found to be ...

The purpose of this study was to compare the appearance of the entire length of the oviductal canal in women with unilateral versus bilateral proximal tubal occlusion. Eleven women had apparent unilateral disease and 18 had apparent bilateral occlusion. Proximal occlusion was confirmed both by hysterosalpingography and laparoscopy. Falloposcopic examination ...

Includes bibliographical references.

BACKGROUND AND PURPOSE: Stroke is an uncommon sequela of Wegener's granulomatosis, resulting primarily from vasculitic infiltration of small to medium-sized vessels. We describe a young patient with Wegener's granulomatosis and basilar artery occlusion. CASE DESCRIPTION: A 26-year-old man with histopathologically confirmed Wegener's granulomatosis suffered a brain stem stroke 24 hours ...

Temporary occlusion of intracranial arteries has emerged as a valuable technical adjunct in the management of intracranial aneurysms. The current study considered 121 patients (from a group of 234 consecutive aneurysm patients treated during a 2-yr period) who underwent elective temporary arterial occlusion. Twenty-one patients were excluded from further study ...

Seminal carnitine levels were studied in 67 patients with obstructive azoospermia. In 25 patients a bilateral vasectomy had been performed previously and for refertilization a vasovasostomy was performed. In the remaining 42 men the occlusion was located within the epididymis. In postvasectomy cases and when the occlusion was located in ...

It is now accepted that repetitive 2-min coronary occlusion can develop collateral vessels to the area perfused by the occluded coronary artery. However, which factors influence collateral development has yet to be fully elucidated. The goal of the present study was to identify the determinants of the rate of coronary ...

The results of several experimental studies of focal ischemia and anecdotal observations suggest that leukocytes may contribute to the injury initiated by an arterial occlusion. The timing and the nature of leukocyte responses in evolving brain infarcts (either human or experimental) are incompletely characterized. This is a study of experimental ...

The present study was undertaken to investigate the role of collateral arteries in cochlear circulation by examining the effect of occlusion of branches of the basilar artery on endocochlear DC potential (EP) and cochlear blood flow (CBF). EP and CBF were measured at the basal turn of the cochlea during ...

Thrombolytic therapy is frequently used for the treatment of peripheral arterial occlusion, but clinical predictors of success have not yet been defined. We prospectively evaluated 80 consecutive patients receiving intra-arterial urokinase for acute (< 14 days) ischemia. Fifty-five patients (69%) were treated for bypass graft occlusion and 25 patients (31%) ...

The survival of tissues in the presence of arterial occlusion is critically dependent on the development of collateral blood vessels. Identification of the biochemical mediators and their mechanism of action is fundamental to an understanding of the evolution of the collateral circulation. The ability of PDGF-BB to promote this was ...

Arterial insufficiency of the hands due to vascular spasm-morbus Raynaud is an extremely unpleasant condition. Elicited by cold temperatures, the disease can make it impossible for the patient to go out in cold environments. The condition seldom leads to skin necrosis, which is the case in arterial insufficiency caused by ...

The majority of lower limb arterial occlusions are located in the distal third of the thigh. However, the exact location of occlusions in relation to the surrounding anatomy has never been examined. Duplex ultrasound was used to determine the location of femoropopliteal occlusions in 50 patients by comparing the level ...

Inability to cross the site of occlusion with a guidewire is the most common cause of failed angioplasty. The Glidewire, a kink-resistant, flexible wire with a hydrophilic coating, was applied to 71 (59 total, 12 subtotal) refractory occlusions, resulting in an overall angioplasty success rate of 45%. The Glidewire may ...

Percutaneous transluminal coronary angioplasty of coronary artery occlusions forms a routine part of cardiological practice. However, only a few angiographic variables which might predict success have been investigated and identified. Video densitometry was used to assess structural features of the occlusion that have not been investigated previously. The sharpness and ...

The role of oxygen-derived free radicals as initiators of vascular dysfunction observed 24 hr after transient coronary artery occlusion (15 or 30 min) was examined in the anesthetized dog. A 15-min occlusion increased human serum (HSA) albumin extravasation within anterior myocardium without producing myocardial necrosis or edema. Minimal leukocyte uptake ...

Duplex ultrasound scanning was used to localise and classify aorto-iliac occlusive disease. The study included 76 consecutive examinations of 73 patients with signs suggestive of proximal occlusive disease either by history or from traditional non-invasive laboratory investigation. Duplex ultrasound scanning indicated the presence of significant proximal occlusive disease in 70/101 ...

We describe two patients who developed devastating strokes due to intracranial arterial occlusion 15 weeks and 97 weeks following high dose stereotactic iodine-125 brachytherapy for glioblastoma multiforme. In both cases the occlusion was within the implant volume at points receiving 110-281 Gy and there was no other evidence of significant ...

This paper presents a combination of several occlusal concepts designed to contribute to the successful use of maxillary dentures in opposition to osseointegrated mandibular prostheses. To ensure a positive outcome when designing such an occlusion, three factors must be considered: patient satisfaction, maxillary anterior bone preservation, and mandibular arch shortening. ...

It is important to determine preoperatively which patients can tolerate permanent occlusion of a cervical internal carotid or cerebral artery when such a procedure may be necessary to treat cerebrovascular or neoplastic lesions. Here we report our experience in combining temporary intra-arterial balloon occlusion with concomitant cerebral blood flow imaging ...

A foreknowledge of impending femoral artery occlusion might allow prevention of a deterioration in ischaemia by percutaneous transluminal angioplasty (PTA) in the preocclusive stage. A window of opportunity exists before a femoral stenosis progresses to occlusion and its treatment by PTA becomes more difficult, riskier and associated with lower patency. ...

BACKGROUND: Paraplegia after thoracic aortic aneurysm has an incidence of 2.2% to 24%. This study was planned to show the beneficial effects of prostacyclin on spinal cord ischemia. METHODS: Twelve rabbits underwent 30 minutes of aortic occlusion. Six rabbits received prostacyclin, whereas the remaining rabbits did not. Prostacyclin administration was ...

A prospective, blinded comparison of two-dimensional time-of-flight (TOF) magnetic resonance (MR) angiography and conventional arteriography was performed in 25 patients who underwent routine arteriography for symptomatic atherosclerotic occlusive disease of the lower extremity. MR angiography was performed from the distal abdominal aorta through the popliteal trifurcation. The native arterial tree ...

One hundred patients with symptomatic peripheral vascular disease were treated with a directional atherectomy catheter; 153 lesions comprising 98 stenoses and 55 occlusions were located in the iliac (n = 22), superficial femoral (n = 114), popliteal (n = 16), and anterior tibial (n = 1) arteries. The majority of ...

BACKGROUND: This study investigated the effects of ischemic preconditioning on myocardial carnitine-linked metabolism and high-energy phosphates in the canine model of ischemia and reperfusion. METHODS: Anesthetized dogs underwent 1 hour of coronary artery occlusion and 4.5 hours of reperfusion. The dogs were randomly assigned to a control group (no intervention ...

The efficacy and safety of recombinant tissue-type plasminogen activator (rt-PA) was evaluated in 46 patients with thromboembolic arterial occlusions in leg arteries. rt-PA was given over 1-4 h with a maximum dose of 18 mg. The effect of rt-PA treatment was determined as patency of the occluded arteries in 44 ...

This review of acute visual failure covers the clinical manifestations and management of ocular strokes CRA occlusion, BRA occlusion and AION. The diagnostic process for each patient requires meticulous attention to: 1. Blood pressure, heart rate and rhythm, palpation of the temporal arteries, and auscultation of the heart, neck, eyes ...