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Results 351 - 400 of 542
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Keen R R - - 1991
OBJECTIVE: To determine whether plasma lipid hydroperoxides may be a useful marker for sepsis. DESIGN: Exploratory, open-label study. SETTING: Critical care unit at a university medical center. PATIENTS: Twelve patients with sepsis syndrome requiring hemodynamic monitoring with pulmonary artery catheters. Seven patients were diagnosed with pulmonary infections and five patients ...
Berridge D C - - 1991
Arteriography does not reliably distinguish between acute and chronic arterial occlusions. Seventeen patients with acute lower limb ischaemia were investigated by arteriography and by imaging with a platelet-specific monoclonal antibody (P256 Fab'); 20 MBq 111In-labelled P256 Fab' was administered intravenously and patients were imaged at intervals of between 20 min ...
St George J K - - 1991
Intra-arterial 99mTc colloid scintigraphy may have greater sensitivity than either standard intravenous scintigraphy or selective arteriography in detecting gastrointestinal bleeding. Ten millicuries of 99mTc colloid were administered directly into the superior and inferior mesenteric arteries (SMA and IMA) of patients who had undergone selective arterial catheterization for the evaluation of ...
Goldman G - - 1991
An extravascular chemoattractant leads to migration of polymorphonuclear neutrophils (PMN) to that site, whereas intravascular administration leads to PMN oxidative activity and sequestration in microvessels but no diapedesis. This study examines the inhibitory role of intravascular chemoattractants. Rabbits (n = 37) were pretreated with zymosan-activated plasma (ZAP), leukotriene (LT) B4, ...
Alavaikko A - - 1991
Eleven patients with acute arterial occlusion of the lower limb were treated by standard balloon catheter embolectomy. Residual thrombus seen in intraoperative arteriograms was treated with streptokinase: after an initial dose of 10.000 IU, streptokinase was infused intra-arterially in a dose of 5.000-10.000 IU/hour. The average infusion time was 40 ...
Hla K M - - 1991
Pseudohypertension in the elderly occurs when blood pressure is overestimated because of inelastic, sclerotic arteries. Osler's maneuver (OM), the palpability of a pulseless artery, is recommended as a non-invasive test to detect pseudohypertension, despite limited data concerning its reproducibility. We assessed the maximum achievable inter-and intra-observer agreement of OM among ...
Mügge A - - 1990
The case of a patient with acute occlusion of the right renal artery due to an embolus is described. Using transoesophageal echocardiography, the left atrial appendage could be identified as the source of embolism. Twenty hours after the onset of symptoms, the embolus could be successfully dissolved with an intra-arterial ...
Dorr R T - - 1990
The foregoing sections have reviewed the experimental studies and clinical anecdotes describing potential pharmacologic antidotes to extravasations of vesicant anticancer agents. Numerous prior reviews have also suggested specific antidotes or very conservative, non-pharmacologic approaches. Many antidotal approaches to extravasation have not been experimentally validated and thus, few 'antidotes' share a ...
Taweepoke P - - 1990
Acute ischaemia of the hand following the accidental intra-arterial injection of steroid has not, to our knowledge, been previously reported. We present such a case of the injection of Depo-Medrone with Lidocaine (Upjohn) into the right radial artery during attempted treatment of stenosing tenosynovitis of the right thumb. The resultant ...
Peene P T - - 1989
In patients with low degree stenoses of the iliofemoral arteries, a discrepancy can occur between the clinical complaints and the severity of the angiographic lesions. Intra-arterial injection of 20 mg of papaverine by mimicking the need for augmented blood supply during exercise will help to objectify the clinical importance of ...
Kennedy A - - 1989
Cholesterol embolism is an unusual but serious complication of intra-arterial procedures such as arteriography and angioplasty. The pathological findings in four cases confirm that this syndrome is due to disseminated micro-emboli composed mainly of cholesterol crystals and that these originate from atheromatous plaques in the aorta which may be traumatized ...
Comerota A J - - 1989
Acute arterial embolic or thrombotic occlusion of the runoff vessels is associated with an incomplete operative thromboembolectomy and an unacceptably high rate of amputation. This report presents a six year analysis of the use of intraoperative intra-arterial thrombolytic therapy, evaluating 38 patients who presented with impending loss of limb because ...
Farber H W - - 1989
Pulmonary hypertension and foreign body granulomas are complications of the chronic intravenous injection of crushed, suspended pentazocine (Talwin) tablets. To evaluate the early cellular mechanisms underlying the response of the lung to foreign body microemboli, we examined lung histopathology and bronchoalveolar lavage (BAL) fluid in dogs for accumulation of inflammatory ...
Fish L R - - 1989
A case of temporary complete paralysis of cranial nerves III, IV, and VI, after a Gow-Gates injection is reported. The proposed explanations for the mechanisms of occurrence are described. Although the Gow-Gates technique has many advantages, it is not without complications. To avoid such complications, it is important to take ...
Doerschuk C M - - 1989
Complement activation in vivo produces neutropenia and pulmonary sequestration of neutrophils (PMNs) whereas in vitro activation increases PMN adherence and decreases PMN deformability. The present study examined PMN kinetics in vivo to determine if this sequestration was specific to the lung. Venous or arterial injections of radiolabeled PMNs were given ...
Bettmann M A - - 1989
Ioversol, the new nonionic, low-osmolality contrast agent, has been well characterized chemically and in terms of basic toxicity testing. Ioversol has a formula similar to that of other nonionic agents, and has been used in a variety of clinical studies. These have been reviewed in detail in other papers. This ...
Weinbaum P J - - 1989
This report describes the antenatal sonographic identification of a hyperechoic intra-abdominal mass in a 30-week fetus. The mass was proved by autopsy to be an extralobar pulmonary sequestration. Although a rare type of congenital malformation, pulmonary sequestration should be included in the differential diagnosis of an echodense intra-abdominal mass seen ...
Shapiro B A - - 1989
The reliability and accuracy of an intra-arterial fluorescent optode system to measure continuously pHa, PaCO2, and PaO2 were evaluated in a dog model and in a group of critically ill patients. Six hundred sixty-three arterial blood gas (ABG) samples were analyzed for pHa, PaCO2, and PaO2 in the dog studies. ...
Jang I K - - 1989
Acute myocardial infarction is triggered by coronary artery occlusion that may be recanalized by thrombolytic therapy with a success rate of up to 75% only. The resistance of coronary artery occlusion to thrombolysis may either be due to obstruction of the lumen by a nonthrombotic mechanism or by intrinsic resistance ...
- - 1989
Authors report the results of the treatment of acute ischemia of the limbs with urokinase in patients included in a polycentric study group called "Bologna". A total of 111 patients affected with acute ischemias of the limbs caused by arterial or graft thromboses were treated with intra-arterial urokinase with a ...
Gmelin E - - 1989
Studies of the intra-arterial bolus curve after intravenous contrast injection with dynamic computed tomography show that a higher bolus maximum can be obtained with a central injection than with a peripheral injection, other injection parameters remaining unchanged. In a singular venous injection ionic and nonionic contrast media show no different ...
Wada Y - - 1989
The tumor cell kinetics before and after intra-arterial injection of cisplatin (CDDP) was examined in a patient with maxillary carcinoma using flow cytometry and propidium iodide and fluorescein isothiocyanate labeled bromodeoxyuridine double staining. In addition, the viability was determined with fluorescein diacetate and compared with the histological picture. The action ...
Mingoli A - - 1989
Two cases of acute leg ischemia from unilateral occlusion of an aorto-bifemoral graft, treated with high-dose urokinase intra-arterial infusion, are reported. This therapy allowed identification of the cause of thrombosis, recanalization of the graft and planning of reoperation. Indications for intra-arterial thrombolytic therapy and advantages of urokinase vs streptokinase are ...
Kahn C E CE - - 1989
Intraarterial administration of chemotherapeutic agents provides greater local concentration at the tumor site without increased systemic toxicity. Although intravenous infusion of cisplatin is known to cause peripheral neuropathy and intraarterial administration has been reported to cause lumbosacral plexopathy, brachial plexopathy has not been described. We present a case in which ...
Greenberg H S - - 1988
A primate toxicity study was performed to test the hypothesis that BUdR does not increase the likelihood of unilateral or bilateral central nervous system damage secondary to radiation therapy. BUdR, a halogenated pyrimidine analog is incorporated into DNA of dividing cells and sensitizes them to radiation. It is best given ...
Allely M C - - 1988
The effects of the novel Class Ia/III antiarrhythmic compound RS-87337 on canine myocardial conduction were compared with those of the Class I antiarrhythmic disopyramide. RS-87337 had no effects on intra-atrial (I-A) or intra-ventricular (I-V) conduction parameters up to 10 mg.kg-1 i.v. (n = 6). Only one incidence of atrioventricular (A-V) ...
Johanson V - - 1988
A technique for in vivo infusion in the superior thyroid artery in rats and mice was developed and evaluated. The influx catheter is inserted in retrograde direction into the superior carotid artery. The infusate mixed with blood is directed exclusively to the thyroid lobe via the superior thyroid artery. The ...
Pfeifer P M - - 1988
An intra-arterial continuous display oxygen electrode for radial artery cannulation is now available in the UK. Nine catheters were used in patients during and after hypothermic cardiac surgery. Results obtained were compared with those from conventional intermittent blood gas samples. Slow temperature response times negate its use during hypothermic surgery. ...
Uchida T - - 1988
Arterial intimal thickening and thrombosis of the pancreatic artery has frequently been found in Watanabe heritable hyper-lipidemic (WHHL) rabbits. Three of the 20 rabbits used in this study showed histopathological findings such as intra- or inter-lobular fibrosis with lymphocytic infiltration, acinar degenerative changes, ductular proliferation and small ductal dilatations which ...
Butler S P - - 1988
Simultaneous emission and transmission tomography was performed after the injection of [99mTc]MAA in 30 patients undergoing intra-arterial chemotherapy to nonhepatic sites to determine the accuracy of catheter placement. The transmission and emission data were reconstructed in transverse, and optionally, coronal and sagittal planes. The correlation of the emission scan with ...
Hernández Altemir F - - 1988
An intra-arterial chemotherapy procedure in patients with malignant tumours in the oral and maxillo-facial region which, from the vascular point of view, can be dependent on the external carotid artery and/or its branches is presented. Particularly for the prevention of catheter infection, obstruction, etc., a subcutaneous pouch, connected to the ...
Lieblich S E - - 1988
The potential for an accidental intra-arterial injection is present whenever an intravenous route of drug administration is used. Because of the serious nature of the morbidity associated with this iatrogenic injury, and its preventability, this article is presented to update the available information on the etiology, diagnosis, treatment, and prevention ...
Covey D C - - 1988
A number of adverse consequences can result in the upper limb from parenteral drug abuse. Propylhexedrine, a drug similar to amphetamine, is easily obtained and causes severe injury to the limb when injected intra-arterially. This report describes an inadvertent case of intra-arterial propylhexedrine injection into the radial artery, the natural ...
Wharton J - - 1988
The innervation of the pulmonary trunk and pulmonary arterial bed was studied in 17 pigs from birth to 6 months of age. After birth, the pulmonary trunk and extra- and intra-pulmonary arteries contained neurofilament and protein gene-product-immunoreactive nerve fibres in both the adventitia and media. The density of nerve fibres ...
Collen D - - 1987
The effect of combined intravenous infusion of 10 mg of recombinant tissue-type plasminogen activator (rt-PA) and 10 mg of recombinant single-chain urokinase-type plasminogen activator over 1 hour on coronary artery recanalization and on the blood fibrinolytic system was studied in 9 patients with acute myocardial infarction and angiographically confirmed coronary ...
Traughber P D - - 1987
Experience with using intraarterial fibrinolysis in the treatment of occlusive disease of the popliteal artery and runoff vessels is limited. We describe the techniques and results in 25 patients with 30 fibrinolytic infusions of the popliteal and tibial arteries and compare them with the initial and long-term results of treatment ...
McNamara T O - - 1987
In an initial study, 85 patients with 93 thromboembolic occlusions of peripheral arteries or grafts were treated with urokinase by direct intra-arterial infusion. Urokinase was infused directly into the proximal portion of the clot at 4,000 IU/minute for two hours. Arteriography was then repeated. If a channel had been lysed ...
Comerota A J - - 1987
This is a prospective analysis of patients undergoing 34 treatments for arterial thromboses and emboli with intra-arterial thrombolytic therapy. These included acute arterial thromboses, graft thromboses, arterial emboli and pulmonary emboli. Twenty-seven of 34 patients treated had evidence of lysis, 14 had complete lysis, 13 had partial lysis and seven ...
Earnshaw J J - - 1987
Thirty-two patients with acute and subacute limb-threatening peripheral arterial ischaemia were treated with low dose intra-arterial streptokinase infusions. The mean duration of infusion was 38 h. Six patients developed pericatheter thrombosis and two had distal embolization of fragments of thrombus but in all cases these responded to repositioning the catheter ...
Pickrell L - - 1987
A 39-year-old man with a left parietal malignant glioma was treated with intracarotid infusion of 1,3-bis(2-chloroethyl)-1-nitrosourea (BCNU). Five weeks after a second infusion, he developed inferior altitudinal visual field loss and pallid optic disc edema ipsilateral to the injection. Retinal vasculitis is a well-recognized complication of intra-arterial BCNU infusion. It ...
Earnshaw J J - - 1987
There has been a recent increase in the use of low dose intra-arterial streptokinase infusion for the management of patients with acute peripheral arterial occlusions. Though serious complications using this technique occur less frequently than when using systemic thrombolytic therapy, a case is reported where the catheter used to infuse ...
Battey P M - - 1987
Peripheral arterial thromboembolism and thrombosis of arterial grafts continue to threaten viability of extremities. Percutaneous intra-arterial thrombolysis (IAT) and angiodilatation have afforded limb salvage in some of these patients. Proper patient selection appears to be the hallmark of success with IAT. During a recent three-year period, we used IAT in ...
Spencer J A - - 1987
This paper describes the performance characteristics of a dual-inlet mass spectrometer suitable for continuous monitoring of maternal and fetal blood gases using intra-arterial mass spectrometer catheters in the pregnant ewe and skin-surface mass spectrometer probes during human labour. Skin-surface measurements in newborn and adult sheep bore a close and easily ...
Hori T - - 1987
The water-soluble nitrosourea compound ACNU is also lipid-soluble at normal physiological pH levels. It lacks toxic effects on vision that nitrosoureas occasionally produce following intra-arterial administration. In 28 cases of both primary and secondary malignant brain tumors, ACNU was administered at surgery or angiography by three different modes: intravenous injection ...
Imamura M - - 1987
Secretin was injected into a feeding or nonfeeding artery of a gastrinoma and blood samples were taken from the hepatic vein (HV) or a peripheral artery (PA) to measure the changes of serum immunoreactive gastrin concentration (IRG). The IRG in the HV rose within 40 seconds and in the PA ...
Plotz R D - - 1987
A retrospective review of 36 neonatal autopsies was undertaken to determine whether blood transfusion was related to pulmonary arterial thrombi at autopsy. The number of transfusions and amount transfused were compared with an estimate of the number of thrombi in the pulmonary arterial tree, determined by a point-counting method. No ...
Smith D C - - 1987
Twenty-five patients were observed in a prospective crossover study to determine whether the new low-osmolality contrast agents would be less prone than conventional agents to produce coughing during pulmonary arteriography. Selective left and right pulmonary arteriography (two views of each side) was performed with alternating administrations of diatrizoate sodium meglumine ...
Zdeblick T A - - 1987
We compared the efficacy of intra-arterial infusion of urokinase, a fibrinolytic agent, with that of intra-arterial infusion of nitrendipine, a peripheral calcium-channel blocking agent, in preventing the no-reflow phenomenon in rats after prolonged ischemia at room temperature. Urokinase increased the survival of the limbs after both four and five hours ...
Prada A - - 1987
In view of the good results obtained with benzydamine against oral radio-chemomucositis in a previous trial, a double-blind/placebo study was undertaken in order to ascertain the possible oral histoprotective effect of benzydamine mouthwash during the intra-arterial polychemotherapy and/or radiotherapy for neoplasms of the head and neck. Statistical comparison of the ...
Huang D X - - 1987
The thrombolytic efficacy of defibrase (DF) and urokinase (UK) was evaluated and compared in a canine model in which left circumflex coronary artery (LCX) thrombus formation was initiated by electrical stimulation (150 UA, DC) of the arterial intimal surface via an implanted copper wire electrode. Forty-eight mongrel dogs were equally ...
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