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Morisaki Akimasa A Department of Cardiovascular Surgery, Osaka City General Hospital, Osaka, Japan - - 2014
In mitral valve repair, removal of mitral annular calcification (MAC) is necessary to secure the artificial ring but may cause rupture of the left ventricle or injury to the circumflex coronary artery. We experienced 3 cases of mitral valve regurgitation with extensive MAC. Patient 1, an 83-year old woman, had ...
Casullo Joseph J 1 Both authors: Department of Diagnostic Radiology, Montreal General Hospital, McGill University Health Center, 1650 Cedar Ave, Montreal, QC H3G 1A4, - - 2014
OBJECTIVE. The purpose of this study was to show the arrangement and connections of the bronchopulmonary veins (i.e., vessels draining the bronchi, bronchioles, and pleura in patients with chronic superior vena cava (SVC) or left brachiocephalic vein (LBCV) obstruction using CT. MATERIALS AND METHODS. Contrast-enhanced CT scans of the chest ...
Kouznetsov Evgueni E Department of Radiology, CHUM, Montréal, Québec, - - 2014
Object In patients with posterior fossa arteriovenous malformations (AVMs) who present with hemorrhage, feeding artery aneurysms are often the source of bleeding. The aim of this study was to evaluate the relative proportions of cases of infra- and supratentorial AVMs in which patients presented with prenidal aneurysm rupture. The management ...
Sakao Seiichiro S Dept of Respirology (B2), Graduate School of Medicine, Chiba University, Chiba, Japan. Victoria Johnson Center for Obstructive Lung Diseases and Pulmonary and Critical Care Medicine Division, Virginia Commonwealth University, Richmond, VA, USA. - - 2014
The loss of pulmonary vessels has been shown to be related to the severity of pulmonary hypertension in patients with chronic obstructive pulmonary disease (COPD). The severity of hypoxaemia is also related to pulmonary hypertension and pulmonary vascular resistance in these patients, suggesting that the hypoxic condition probably plays an ...
Thorat Ashok A Chang-Gung Transplantation Institute, Department of Liver and Transplantation Surgery, Chang-Gung Memorial Hospital, College of Medicine, Chang-Gung University, Taoyuan, - - 2014
Hepatic artery pseudoaneurysm after liver transplantation is an uncommon but potentially lethal complication. Early diagnosis and treatment are essential to avoid life-threatening hemorrhage in these patients. We herein report the case of three patients who developed hepatic artery pseudoaneurysms after living donor liver transplantation. Two patients presented with massive duodenal ...
Kim Jae-Gyum JG Department of Neurology, Korea University College of Medicine, Korea University Anam Hospital, Republic of - - 2014
Headache may be a warning sign of subsequent stroke in patients with vertebral artery dissection (VAD). Even though the headache characteristics of VAD have been described predominantly in patients with extracranial VAD and neurological complications, headache semiology is not well known in patients with uncomplicated intracranial vertebral artery dissection (ICVAD). ...
Khajali Zahra Z Rajaei Cardiovascular Medical & Research Center, Iran University of Medical Sciences, Tehran, Iran, - - 2014
Treatment of prosthetic heart valve thrombosis using intravenous thrombolytics, although an acceptable alternative to surgery, is not complication free, and the literature has a dearth of data on the subject. This study analyzed the results of fibrinolytic treatment (FT) among a single-center group of patients with mechanical pulmonary valve thrombosis. ...
Chavent Adrien A Departments of Neuroradiology - - 2014
The authors present the cases of 3 patients with ruptured perforator aneurysms of the posterior circulation. Patients were 39, 55, and 59 years old. None of the patients had relevant past medical or family history. All presented with World Federation of Neurosurgical Societies Grade I and Fisher Grade 2 or ...
Gülcü Aytaç A Department of Radiology, Faculty of Medicine, Dokuz Eylul University, Izmir, Turkey. Electronic address: - - 2014
Clinical management strategy and the best treatment option of free floating thrombus (FFT), detected in patients with acute ischemic cerebrovascular diseases is still uncertain due to the rarity of these conditions. Recent studies emphasize that FFT within cerebral vessels may not be a surgical emergency since complete dissolution without any ...
Clerico C C Service de chirurgie de la main, hôpital Saint-Roch, rue Pierre-Devoluy, 06000 Nice cedex 3, France. Electronic address: - - 2014
Vascular complications of wrist arthroscopy are rare. We report the case of a 42-year-old male patient with a history of hemophilia who had a ganglion located where the radial pulse is taken that had been causing him pain for five months. After infusion of Exacyl (antifibrinolytic agent), the ganglion was ...
Finn Matthew M Department of Cardiology, Columbia University Medical Center, New York, NY. Electronic address: - - 2014
In recent years, experience with transcatheter aortic valve implantation has led to improved outcomes in elderly patients with severe aortic stenosis (AS) who may not have previously been considered for intervention. These patients are often frail with significant comorbid conditions. As the prevalence of AS increases, there is a need ...
Ollikainen Eliisa E From the Doctoral Program in Biomedicine, Doctoral School in Health Sciences, University of Helsinki (EO); Neurosurgery Research Group (EO, RT, JF, PH, JH, MN) and Wihuri Research Institute (EO, SL, PTK), Biomedicum; Department of Neurosurgery, Helsinki University Central Hospital (JH, MN), Helsinki; and Department of Neurosurgery, Kuopio University Hospital (JF), Kuopio, - - 2014
Chronic inflammation contributes to remodeling, degeneration, and rupture of saccular intracranial artery aneurysms. Mast cells are important proinflammatory and proangiogenic cells in chronic inflammatory vascular diseases. Here we studied mast cells and neovascularization in 36 intraoperatively resected aneurysms using histology and immunohistochemistry and analyzed the clinical characteristics of the aneurysms ...
Olschewski Andrea A Ludwig Boltzmann Institute for Lung Vascular Research, Graz, Austria; Experimental Anesthesiology, Department of Anesthesia and Intensive Care Medicine, Medical University of Graz, Austria. Electronic address: - - 2014
The pulmonary circulation is a low pressure, low resistance, high flow system. The low resting vascular tone is maintained by the concerted action of ion channels, exchangers and pumps. Under physiological as well as pathophysiological conditions, they are targets of locally secreted or circulating vasodilators and/or vasoconstrictors, leading to changes ...
Uthayakumaran Kalaichelvan K Consultant, Department of Cardiology, Institute of Cardio-Vascular Diseases, Madras Medical Mission, Chennai, India. Electronic address: - - 2014
To assess the technical challenges in percutaneous coronary intervention of Anomalous right coronary artery arising from the left sinus of valsalva. Between year 2008 and 2012, a total of 17 patients underwent PCI for an angiographically significant lesion in the right coronary artery of an anomalous origin in the LSOV. ...
Robinson Jeffrey C JC Program in Translational Lung Research, Division of Pulmonary Sciences and Critical Care Medicine, Department of Medicine, University of Colorado School of Medicine, Aurora, Colorado, United States ; - - 2014
The pathologic hallmark of pulmonary arterial hypertension is pulmonary vascular remodeling - characterized by endothelial cell proliferation, smooth muscle hypertrophy, and perivascular inflammation - ultimately contributing to increased pulmonary arterial pressures. Several recent studies have observed that iron deficiency in patients with various forms of pulmonary arterial hypertension is associated ...
Ayala-Lopez N N Department of Pharmacology and Toxicology, Michigan State University, East Lansing, MI - - 2014
The sympathetic nervous system and its neurotransmitter effectors are undeniably important to blood pressure control. We made the novel discovery that perivascular adipose tissue (PVAT) contains significant concentrations of catecholamines. We hypothesized that PVAT contains sufficient releasable catecholamines to affect vascular function. HPLC, isometric contractility, immunohistochemistry, whole animal approaches and ...
Lin Huili H AtlantiCare Medical Center, Pomona, New Jersey, - - 2014
A patient with Turner syndrome presented with shortness of breath with exertion. Three-dimensional transesophageal echocardiogram revealed a bicuspid aortic valve with severe aortic stenosis. There were multiple masses attached to the aortic valve and tricuspid valve, which mimicked vegetations. The patient underwent aortic and tricuspid valve replacement. Histology revealed papillary ...
Winner Marshall W MW 3rd Ohio State University, Davis Heart and Lung Research Institute, Columbus, - - 2014
Iron has been implicated in atherogenesis and plaque destabilization, whereas less is known about iron-related proteins in this disease. We compared ex vivo quantities with in vivo vessel wall T2*, which is a noncontrast magnetic resonance relaxation time that quantitatively shortens with increased tissue iron content. We also tested the hypothesis that ...
Kazemzadeh Gholam Hossein GH From the *Department of Vascular Surgery, and †Nuclear Medicine Research Center, Faculty of Medicine, Imam Reza Hospital, Mashhad University of Medical Sciences, Mashhad, - - 2014
Chylous reflux is described as the backflow of chyle through the varicose lymphatics with incompetent lymph valves and leakage of the lymph. The valves in the dilated, varicose, tortuous lymph vessels become incompetent, and as a result, the lymph blended with chyle, reflux into the lower limbs or the genitalia. ...
Biscotti Mauer M * Columbia University Medical Center, 177 Fort Washington Ave., New York, NY, 10032, Department of General Surgery ¶ New York Presbyterian Hospital/ Columbia University Medical Center, 177 Fort Washington Ave., New York, NY, 10032, Department of Pulmonary, Allergy, and Critical Care Medicine & New York Presbyterian Hospital/ Columbia University Medical Center, 177 Fort Washington Ave., New York, NY, 10032, Department of Cardiothoracic - - 2014
Traumatic injury to the aortic valve is an uncommon clinical entity. Rarer still is transport of such a patient using Extracorporeal Membrane Oxygenation (ECMO) to a specialized ECMO center for definitive repair. We present a case of traumatic rupture of the aortic valve complicated by severe ARDS with inter-hospital transport ...
Yamashita Atsushi A Department of Pathology, University of Miyazaki, Miyazaki, - - 2014
Inflammation and possibly hypoxia largely affect glucose utilization in atherosclerotic arteries, which could alter many metabolic systems. However, metabolic changes in atherosclerotic plaques remain unknown. The present study aims to identify changes in metabolic systems relative to glucose uptake and hypoxia in rabbit atherosclerotic arteries and cultured macrophages. Macrophage-rich or ...
Denny William J WJ Centre for Applied Biomedical Engineering Research (CABER), Department of Mechanical, Aeronautical and Biomedical Engineering and Materials and Surface Science Institute, University of Limerick, Limerick, - - 2014
Coronary artery disease results in blockages or narrowing of the artery lumen. Drug eluting stents were developed to replace bare metal stents in an effort to combat re-blocking of the lumen. A key element in determining the therapeutic success of a drug eluting stent is an in-depth understanding of the ...
Dikalova Anna A Dept. of Pediatrics, Vanderbilt University Medical Center, Nashville, Tennessee, United States of America ; Monroe Carell Jr. Children's Hospital at Vanderbilt, Nashville, Tennessee, United States of - - 2014
There is evidence that impairments in nitric oxide (NO) signaling contribute to chronic hypoxia-induced pulmonary hypertension. The L-arginine-NO precursor, L-citrulline, has been shown to ameliorate pulmonary hypertension. Sodium-coupled neutral amino acid transporters (SNATs) are involved in the transport of L-citrulline into pulmonary arterial endothelial cells (PAECs). The functional link between ...
Zimnicka Adriana M AM Department of Medicine, Section of Pulmonary, Critical Care, Sleep and Allergy Medicine, University of Illinois at Chicago, Chicago, Illinois, United States of - - 2014
Pulmonary vascular remodeling and increased arterial wall stiffness are two major causes for the elevated pulmonary vascular resistance and pulmonary arterial pressure in patients and animals with pulmonary hypertension. Cellular copper (Cu) plays an important role in angiogenesis and extracellular matrix remodeling; increased Cu in vascular smooth muscle cells has ...
Wittwer Erica D ED Division of Critical Care Medicine and Cardiothoracic Anesthesia, Department of Anesthesiology, Mayo Clinic College of Medicine, 200 First Street SW, Rochester, MN 55905, - - 2014
The purpose of this case is to describe the complex perioperative management of a 30-year-old woman with congenital heart disease and multiple resternotomies presenting with pulmonary homograft dysfunction and evaluation for percutaneous pulmonary valve replacement. Transvenous, transcatheter Melody valve placement caused left main coronary artery occlusion and cardiogenic shock. An ...
Kloza Monika M Zakład Fizjologii i Patofizjologii Doświadczalnej Uniwersytetu Medycznego w - - 2014
Tętnicze nadciśnienie płucne jest postępującą chorobą, prowadzącą do niewydolności prawej komory serca i przedwczesnej śmierci. Charakteryzuje się podwyższonym ciśnieniem w tętnicy płucnej, zwiększeniem oporu naczyniowego, przebudową naczyń płucnych oraz dysfunkcją śródbłonka. Patomechanizm tej choroby jest wciąż nieznany. Sugeruje się, że dysfunkcja śródbłonka zaburza równowagę między czynnikami wazodylatacyjnymi a wazokonstrykcyjnymi, w ...
Wu Chao C State Key Laboratory of Cardiovascular Disease, Fu Wai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100037, - - 2013
To overcome the drawbacks of permanent stents, biodegradable stents have been studied in recent years. The bioabsorbable polymer vascular scaffold (BVS) was the first bioabsorbable stent to undergo clinical trials, demonstrating safety and feasibility in the ABSORB studies. Iron can potentially serve as the biomaterial for biodegradable stents. This study ...
Pal Jyotirmoy - - 2013
Pulmonary hypertension is an important cause of dyspnoea in human immunodeficiency virus/acquired immune deficiency syndrome (HIV/AIDS) patients. The effect highly active antiretroviral therapy on pulmonary artery pressure has been an area of controversy. The purpose of this study was to evaluate the effect of antiretroviral therapy on pulmonary hypertension in ...
Sommer Karsten - - 2013
Myocardial blood flow (MBF) quantification using contrast-enhanced first-pass magnetic resonance imaging relies on the precise knowledge of the arterial input function (AIF). Due to vascular transport processes, however, the shape of the AIF may change from the left ventricle where the AIF is measured to the myocardium. We employed computational ...
Kenjeres Sasa - - 2014
A high concentration of low-density lipoprotein (LDL) is recognized as one of the principal risk factors for development of atherosclerosis. This paper reports on modelling and simulations of the coupled mass (LDL concentration) and momentum transport through the arterial lumen and the multi-layered arterial wall of an anatomically realistic carotid ...
Denny William J - - 2013
Coronary artery disease results in blockages or narrowing of the artery lumen. Drug eluting stents (DES) were developed to replace bare metal stents in an effort to combat re-blocking of the diseased artery following treatment. The numerical models developed within this study focus on representing the changing trends of drug ...
Corrales-Medina Fernando F - - 2013
Cerebral sinovenous thrombosis is a rare condition presenting with a wide spectrum of nonspecific symptoms that can make early diagnosis difficult. Cerebral sinovenous thrombosis has been associated with various etiologies. Iron deficiency anemia associated with cerebral sinovenous thrombosis in teenagers is rare. We present a teenage patient with complete thrombosis ...
Jiao Liqun L Department of Neurosurgery, Xuanwu Hospital, Capital Medical University, Beijing 10053, - - 2013
This study aimed to summarize therapy experience of carotid endarterectomy, carotid endarterectomy combined with Fogarty catheter embolectomy, and hybrid surgery for the treatment of extracranial internal carotid artery occlusion. The study included 65 patients with extracranial internal carotid artery occlusion who underwent carotid endarterectomy, carotid endarterectomy combined with Fogarty catheter ...
Vincent P E - - 2013
Atherosclerosis is the underlying cause of most heart attacks and strokes. It is thereby the leading cause of death in the Western world, and it places a significant financial burden on health care systems. There is evidence that complex, multi-scale arterial mass transport processes play a key role in the ...
Carr Ian A - - 2013
While it is intuitively clear that aortic anatomy and embolus size could be important determinants for cardiogenic embolic stroke risk and stroke location, few data exist confirming or characterizing this hypothesis. The objective of this study is to use medical imaging and computational modeling to better understand if aortic anatomy ...
Nadlonek Nicole A NA Division of Cardiothoracic Surgery, Department of Surgery, University of Colorado School of Medicine, Aurora, Colorado 80045, - - 2013
The aortic valve interstitial cell (AVIC) has been implicated in the pathogenesis of calcific aortic stenosis. When appropriately stimulated, AVICs undergo a phenotypic change from that of a myofibroblast to that of a bone-forming-like cell. An elevated blood level of low-density lipoprotein (LDL) cholesterol is a clinical risk factor for ...
Saad Rasheed A - - 2013
Heyde syndrome (the combination of iron deficiency anemia and aortic stenosis) has been a controversial entity. The proposed mechanisms between aortic valve disease and iron deficiency anemia are examined in this article along with impact valve replacement on iron deficiency anemia.
Fernández-Hernando Carlos C Department of Medicine, Leon H. Charney Division of Cardiology and the Marc and Ruti Bell Vascular Biology and Disease Program, New York University School of Medicine, New York, New York, USA. - - 2013
Reverse cholesterol transport (RCT) is the pathway by which cholesterol accumulated in peripheral tissues, including the artery wall, is transported to the liver for excretion. There is strong evidence suggesting that interventions that increase macrophage cholesterol efflux and RCT would be antiatherogenic. In this issue of the JCI, Martel et ...
Bäck Magnus - - 2013
The biomechanical factors that result from the hemodynamic load on the cardiovascular system are a common denominator of several vascular pathologies. Thickening and calcification of the aortic valve will lead to reduced opening and the development of left ventricular outflow obstruction, referred to as aortic valve stenosis. The most common ...
Türkmen Nursel - - 2013
Barotraumas and decompression sickness are the two most well-known complications of diving. First presented case was 32 year-old male with recreational diver, who was found floating prone position on the bottom of sea in a depth of 33 m. He had been carried to the surface in a controlled ascent. ...
Denny William J - - 2012
The development and use of drug eluting stents has brought about significant improvements in reducing in-stent restenosis, however, their long term presence in the artery is still under examination due to restenosis reoccurring. Current studies focus mainly on stent design, coatings and deployment techniques but few studies address the issue ...
Keyes Joseph T JT Graduate Interdisciplinary Program in Biomedical Engineering, The University of Arizona, Tucson, Arizona, 85721, - - 2013
Arterial wall mass transport properties dictate local distribution of biomolecules or locally delivered dugs. Knowing how these properties vary between coronary artery locations could provide insight into how therapy efficacy is altered between arterial locations. We introduced an indocarbocyanine drug surrogate to the lumens of left anterior descending and right ...
Feng Qimao - - 2012
A bio-corrodible nitrided iron stent was developed using a vacuum plasma nitriding technique. In the nitrided iron stents, the tensile strength, radial strength, stiffness and in vitro electrochemical corrosion rate were significantly increased compared with those of the control pure iron stent. To evaluate its performance in vivo, the deployment ...
Behnke Bradley J BJ Department of Applied Physiology and Kinesiology, University of Florida, Gainesville, FL 32611-8205, - - 2013
Following exposure to microgravity, there is a reduced ability of astronauts to augment peripheral vascular resistance, often resulting in orthostatic hypotension. The purpose of this study was to test the hypothesis that mesenteric arteries and veins will exhibit diminished vasoconstrictor responses after spaceflight. Mesenteric arteries and veins from female mice ...
Keyes Joseph T JT Graduate Interdisciplinary Program in Biomedical Engineering 1657 E Helen St, The University of Arizona, Tucson, AZ 85721, USA. - - 2013
Understanding coronary artery mass transport allows researchers to better comprehend how drugs or proteins move through, and deposit into, the arterial wall. Characterizing how the convective component of transport changes based on arterial location could be useful to better understand how molecules distribute in different locations in the coronary vasculature. ...
Ellis Harold - - 2012
In the German surgical journal Zentralblatt fur Chirurgie of 1881, Richard von Volkmann wrote; 'The paralyses and contractures that follow tightly applied bandages, chiefly in the forearm and hand, and less often in the lower extremity, are to be viewed as ischemic. They arise from the arterial supply being interrupted ...
Storck Elisabeth M - - 2012
Rho proteins, best known for their regulatory role in actin dynamics, stimulate a variety of processes important in the control of vascular function, including morphogenesis, migration, cell proliferation and adhesion, cell survival, gene expression, vesicle transport and microparticle formation. Rho GTPases have been implicated in several pulmonary vascular pathologies. Here ...
Bazigou Eleni - - 2013
The efficient transport of blood and lymph relies on competent intraluminal valves that ensure unidirectional fluid flow through the vessels. In the lymphatic vessels, lack of luminal valves causes reflux of lymph and can lead to lymphedema, while dysfunction of venous valves is associated with venous hypertension, varicose veins, and ...
Wong Chi-Ming - - 2012
Reactive oxygen species (ROS) have been implicated in the pathogenesis of pulmonary hypertension. Because iron is an important regulator of ROS biology, this study examined the effects of iron chelation on the development of pulmonary vascular remodeling. The administration of an iron chelator, deferoxamine, to rats prevented chronic hypoxia-induced pulmonary ...
Shimoda Larissa A - - 2012
When exposed to chronic hypoxia (CH), the pulmonary circulation responds with enhanced contraction and vascular remodeling, resulting in elevated pulmonary arterial pressures. Our work has identified CH-induced alterations in the expression and activity of several ion channels and transporters in pulmonary vascular smooth muscle that contribute to the development of ...
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