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Results 251 - 300 of 1944
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Cardinale L - - 2009
This review discusses the usefulness of bedside lung ultrasound in the diagnostic distinction between the various causes of acute dyspnoea in the emergency department, with special attention to the differential diagnosis of pulmonary oedema and exacerbation of chronic obstructive pulmonary disease (COPD). This is made possible by using mid- to ...
Song Y - - 2009
Nano materials generate great benefits as well as new potential risks. Animal studies and in vitro experiments show that nanoparticles can result in lung damage and other toxicity, but no reports on the clinical toxicity in humans due to nanoparticles have yet been made. The present study aimed to examine ...
Taylor Katherine - - 2009
We present a 15-yr-old-girl who underwent interventional lung assist via Novalung (Novalung GmbH, Lotzenaecker, Heckingen, Germany) insertion as a bridge to bilateral lung transplantation for pulmonary veno-occlusive disease. This is the first pediatric and smallest patient to receive the device. Central cannulation was chosen to optimize blood flow through the ...
Jorens P G - - 2009
Nonthrombotic pulmonary embolism (NTPE) is defined as embolisation to the pulmonary circulation of different cell types (adipocytes, haematopoietic, amniotic, trophoblastic or tumour), bacteria, fungi, foreign material or gas. The purpose of this article is to describe the clinical signs, pathogenesis, diagnosis and treatment of the different NTPE subtypes. The complex ...
Asosingh Kewal - - 2009
Plasticity of the lung vasculature is intrinsically more complex than other organs due to the presence of two blood supply systems under different arterial pressures, the pulmonary and bronchial arterial systems. The bronchial and pulmonary circulations may both contribute to vascular remodelling in lungs after injury or inflammation. Vascular remodelling ...
Demmy Todd L - - 2009
BACKGROUND: After promising preclinical studies using a thoracoscopic regional lung chemotherapy technique less morbid than open perfusion methods, we initiated a Phase I clinical study. METHODS: Four performance status 0 to 1 patients with oligometastatic stage IV lung cancer underwent unilateral thoracoscopic lung suffusion targeting the bulk of primary disease ...
Montani David - - 2009
Pulmonary veno-occlusive disease (PVOD) is a rare disorder and can be misdiagnosed as idiopathic pulmonary arterial hypertension (iPAH). PVOD and iPAH often share a similar clinical presentation, genetic background, and hemodynamic profile. PVOD accounts for 5 to 10% of cases initially considered as iPAH. When compared with iPAH, PVOD is ...
Derksen F J - - 2009
REASONS FOR PERFORMING STUDY: Regional veno-occlusive remodelling of pulmonary veins in EIPH-affected horses, suggests that pulmonary veins may be central to pathogenesis. The current study quantified site-specific changes in vein walls, collagen and haemosiderin accumulation, and pleural vascular profiles in the lungs of horses suffering EIPH. HYPOTHESIS: In the caudodorsal ...
Summer Ross - - 2009
Adiponectin (APN) is an adipocyte-derived factor that exists at high concentrations in serum and has anti-inflammatory and systemic vascular-protective properties. In this study, we investigated the role of APN in pulmonary vascular homeostasis. We found that APN localizes to the luminal side of blood vessels in lung and acts in ...
Cerezo Francisco - - 2009
Bronchial and vascular reconstructive procedures are a technically feasible alternative to pneumonectomy in lung cancer and have the advantage of preserving lung parenchyma function. Sleeve resection and prosthetic reconstruction of the pulmonary artery (PA) have progressively gained acceptance as an alternative to pneumonectomy in lung cancer surgery. To spare the ...
Baskar Karthekeyan Ranjith - - 2009
Scimitar syndrome is a rare congenital anomaly characterized by anomalous pulmonary venous drainage to the inferior vena cava, causing a left-to-right shunt. Six patients with scimitar syndrome were diagnosed in our hospital between 2002 and 2008. There were 4 girls and 2 boys; 4 < 5 kg in weight, 2 ...
Wells A U - - 2009
Pulmonary manifestations of SSc are leading causes of disease-related morbidity and mortality. Key clinical issues relate to the early detection of fibrotic lung disease, the interpretation of its significance, and decisions on when to start therapy. Respiratory symptoms are common in patients with SSc, but physical examination often fails to ...
Kamiyoshihara Mitsuhiro - - 2009
In the lung cancer case described here, we resected the right upper lobe, right middle lobe, and superior segment of the right lower lobe with concomitant resection of the pulmonary artery and bronchoplastic and pulmonary arterial reconstruction. The basal segmental bronchus was anastomosed to the right main stem bronchus using ...
Risse Frank - - 2009
The purpose of the study was to evaluate the feasibility of suppressing the pulmonary vasculature in lung perfusion MRI using cross-correlation analysis (CCA). Perfusion magnetic resonance imaging (MRI) (3D FLASH, TR/TE/flip angle: 0.8 ms/2.1 ms/40 degrees ) of the lungs was performed in seven healthy volunteers at 1.5 Tesla after ...
Oguz Berna - - 2009
Horseshoe lung, a rare congenital anomaly, is almost always associated with unilateral (usually right-sided) lung hypoplasia, and, in most cases, in conjunction with the scimitar syndrome. We present an 8-month-old boy with horseshoe lung associated with left-lung hypoplasia, left pulmonary artery sling and bilateral agenesis of the upper lobe bronchi, ...
Yamakado Koichiro - - 2010
A 75-year-old man received lung radiofrequency (RF) ablation to treat lung metastases from hepatocellular carcinoma. Massive hemoptysis occurred 1 week after lung RF ablation. Emergent contrast-enhanced CT and pulmonary arteriography revealed a pulmonary artery pseudoaneurysm, which was embolized with coils. The postembolization course was uneventful. Hemoptysis did not recur for ...
van Tilburg P M B - - 2009
Complete anatomical resection of the primary tumour is still the standard of care in patients with early stage lung cancer. Because these patients are usually smokers who also suffer from chronic obstructive pulmonary disease, regional differences in pulmonary function due to lung tissue destruction exist. The purpose of the present ...
Izbicki Gabriel - - 2009
BACKGROUND: It has been suggested that coronary artery disease (CAD) is a common complicating condition in pulmonary fibrosis. OBJECTIVE: To establish and compare the incidence of coronary artery disease in lung-transplantation candidates with emphysema and lung fibrosis METHOD: All adult patients (age>40 years old) with emphysema or lung fibrosis, candidates ...
Lim Hee Hwan - - 2009
Systemic arterialization of normal lung without sequestration is a rare congenital abnormality. The basal segments of the left lower lobe are most frequently involved. The involved lung has no structural abnormalities of the tracheobronchial tree that distinguish this abnormality from bronchopulmonary sequestration. Haemoptysis and exertional dyspnoea are common presenting symptoms. ...
Das Jyotirmoy - - 2009
Endobronchial blood clot is an unusual cause of airway obstruction leading to lung collapse in the postoperative period. It is not always easy to pin point the exact etiology in the presence of multiple risk factors. Pulmonary collapse can herald the onset of severe haemodynamic derangements and hypoxemia. So, early ...
Daimon Tadahisa - - 2009
PURPOSE: The aim of this study was to measure the volume of each pulmonary segment by volumetric computed tomography (CT) data using a newly developed three-dimensional software application and to identify the differences between those with chronic obstructive pulmonary disease (COPD) and controls. MATERIALS AND METHODS: CT scans of 11 ...
Shang AnDong - - 2009
A 40-year-old woman was hospitalized for investigation of dry cough, dyspnoea, and pain and swelling in the large joints of the arms and legs. Chest CT revealed a left hilar mass with partial atelectasis in the apical segment of the left lower lobe. X-ray of the wrists, elbows, ankles and ...
Strueber M - - 2009
We describe a novel technique of pumpless extracorporeal life support in four patients with cardiogenic shock due to end-stage pulmonary hypertension (PH) including patients with veno-occlusive disease (PVOD) using a pumpless lung assist device (LAD). The device was connected via the pulmonary arterial main trunk and the left atrium, thereby ...
Makanya A N - - 2009
The avian lung has a highly sophisticated morphology with a complex vascular system. Extant data regarding avian pulmonary angioarchitecture are few and contradictory. We used corrosion casting techniques, light microscopy, as well as scanning and transmission electron microscopy to study the development, topography, and distribution of the parabronchial vasculature in ...
Kimura Satoshi - - 2009
Pulmonary arterial hypertension (PAH) is an intractable disease of the small pulmonary artery that involves multiple inflammatory factors. We hypothesized that a redox-sensitive transcription factor, nuclear factor kappaB (NF-kappaB), which regulates important inflammatory cytokines, plays a pivotal role in PAH. We investigated the activity of NF-kappaB in explanted lungs from ...
Li Min-Hui - - 2009
Baicalin has been reported to have anti-inflammatory effects and protect against various tissue injuries. However, the effect of baicalin on air embolism-induced acute lung injury has not been tested yet. Acute lung injury was induced by infusion of air at a rate of 0.25 mL.min(-1) for 1 min into the ...
Kambouchner Marianne - - 2009
It has been assumed for a long time that except for limited areas close to respiratory bronchioles or their satellite arteries, there is no evidence of lymphatic vessels deep in the pulmonary lobule. An immunohistochemical study using the D2-40 monoclonal antibody was performed on normal pulmonary samples obtained from surgical ...
Smodlaka H - - 2009
This investigation serves to document the normal anatomical features of the lower respiratory tract of the ringed seal [Pusa (phoca) hispida]. Evaluation of embalmed specimens and tracheobronchial casts showed that the right lung of this seal consists of four lobes while the left has only three lobes. The ventral margins ...
Zimmermann Gregor S - - 2009
In this report we describe a 42-year-old man with idiopathic pulmonary fibrosis with a progressive course who underwent right single-lung transplantation in November 2007. The post-operative course showed a decline of gas exchange, and chest X-ray revealed pneumonic infiltrates. Computerized tomography (CT) scans showed high-grade stenosis of the right superior ...
Yanagawa Youichi - - 2009
An 8-year-old boy was struck by a truck, and the impact carried him 10 m away from the scene. On arrival at the hospital, his chest and left thigh roentgenograms revealed fractures of the left clavicle, scapular, and left femur shaft. His chest computed tomography scan demonstrated right dominant bilateral ...
Fan Li - - 2010
OBJECTIVE: To evaluate the effect of gravity and lung inflation on pulmonary perfusion heterogeneity in human lung using an arterial spin labeling (ASL) sequence called flow sensitive alternating inversion recovery (FAIR). MATERIALS AND METHODS: Magnetic resonance imaging of lung perfusion using arterial spin labeling sequence was performed in supine position ...
Zöphel Klaus - - 2009
Lung perfusion scintigraphy (LPS) with technetium-99m-labeled macro-aggregates of albumin (Tc-99m-MAA) is well established in the diagnostic of pulmonary embolism (PE). In the last decade, it was shown that single-photon emission computer tomography (SPECT) acquisition of LPS overcame static scintigraphy. Furthermore, there are rare indications for LPS, such as preoperative quantification ...
Kosacka Monika - - 2009
We describe the case of a 61-year-old male patient, in which the search for the cause of chronic respiratory failure, severe pulmonary hypertension and secondary erythrocytosis resulted in a diagnosis of combined pulmonary fibrosis and emphysema (CPFE). This is a unique, recently characterised syndrome with upper-lobe emphysema and pulmonary fibrosis ...
Najafizadeh Katayoun - - 2009
BACKGROUND: Pulmonary artery stenosis after lung transplantation is a rare complication. It usually requires surgical correction but even after that the outcome is not favorable.<br /> CASE REPORT: The patient was a 53-years-old woman who was candidate for lung transplantation surgery due to pulmonary fibrosis. After 7 months on waiting ...
Moreira Marcos Mello - - 2009
Pulmonary embolism (PE) is a common condition. The central aim of this study was to describe the use of volumetric capnography (VCap) before and after fibrinolytic treatment of major PE. Lung scintigraphy was used as a base of comparison for the results of this treatment. We describe the cases of ...
Georgin-Lavialle Sophie - - 2009
The occurrence of an intravascular lymphoma with severe pulmonary involvement mimicking pulmonary embolism is described. A 38-year-old man was referred to our intensive care unit with acute respiratory failure and long lasting fever. Appropriate investigations failed to demonstrate any bacterial, viral, parasitic or mycobacterial infection. A chest computed tomography scan ...
Montani D - - 2009
Pulmonary veno-occlusive disease (PVOD) is currently classified as a subgroup of pulmonary arterial hypertension (PAH) and accounts for 5-10% of cases initially considered to be idiopathic PAH. PVOD has been described as idiopathic or complicating other conditions, including connective tissue diseases, HIV infection, bone marrow transplantation, sarcoidosis and pulmonary Langerhans ...
Sochor Markus - - 2009
BACKGROUND/AIMS: Severe lung injury, responsible for up to 15% of mortality in acute necrotizing pancreatitis patients, is promoted by neutrophil (PMN) migration into the lung. We have previously demonstrated that pulmonary injury in acute pancreatitis is mediated by PMN-derived matrix metalloproteinase-9 (MMP-9). This study was conducted to evaluate the ability ...
Solaini Leonardo - - 2008
A case of bilateral pneumothorax, lung cavitations, and pleural empyema in a cocaine user is described. The patient was treated by left tube thoracostomy and right lower lobectomy. The postoperative course was uneventful. Six months later, the patient remains asymptomatic. The pathology examination of the specimen revealed infected bronchiectasis, interstitial ...
Thachil Jecko - - 2009
Systemic sclerosis (SSc) is an autoimmune connective tissue disease characterized by fibrotic changes in several organs including the lungs, skin, kidneys, muscles and the joints. The leading cause of death in SSc is pulmonary involvement consisting of pulmonary fibrosis with pulmonary hypertension. The pathogenesis of lung involvement in SSc is ...
Zhu Chenting - - 2008
Ischemia reperfusion (I/R) injury of the lung affects the function of the nonischemic lung. Our objective is to determine how apocynin, which is a nicotinamide adenine dinucleotide phosphate (NADPH) oxidase inhibitor, protects the nonischemic control right lung (RL) from injury by the unilateral ischemic left lung (LL). In isolated ventilated ...
Boyd John H - - 2008
The early use of vasopressors in sepsis has been associated with a decrease in immune activation independent of hemodynamic effects, although the mechanism behind this remains unclear. We hypothesize that low dose vasopressin will reduce the pulmonary inflammation associated with sepsis. Our aims were to (1) determine whether vasopressin reduces ...
Li Xiaohui - - 2008
This study aimed to explore the effect of sodium hydrosulfide (NaHS) on pulmonary artery collagen remodeling in rats with high pulmonary blood flow. Thirty-two Sprague-Dawley rats were randomly divided into a sham group, shunt group, sham + NaHS (an H2S donor) group, and shunt + NaHS group. After 11 weeks ...
Mori Natsumi - - 2008
Basic fibroblast growth factor (bFGF) has a variety of activities including regeneration and neovascularization. This study was an attempt to reconstruct emphysematous lung tissue employing slow release of bFGF. Twenty beagle dogs were randomly split into four groups: a) control group (n = 5), b) porcine pancreatic elastase (PPE)-induced emphysema ...
Short Melissa - - 2008
A 4-week-old boy was extensively investigated for stridor and respiratory distress and was found to have a soft tissue mass superior to the left hilum and emphysema of the entire left lung. An exploratory thoracotomy was undertaken for diagnosis and possibly to improve respiratory distress. Intraoperatively, a firm plaquelike mass ...
Yang Jerry Z - - 2008
This manuscript describes the preparation, characterization, and pharmacokinetic studies for fluticasone and budesonide nanosuspensions in pulmonary delivery. A wet-milling method with glass beads was evaluated for formulation preparation. Based on the milling time and glass bead size studies, a 24-h wet-milling process using multisized glass beads was found to be ...
Harel François - - 2008
Currently, there is no low-molecular-weight agent for imaging of the pulmonary circulation. Adrenomedullin (AM) is a peptide predominantly cleared by the pulmonary circulation through specific endothelial receptors. We developed human AM derivatives radiolabeled with 99mTc and evaluated their biodistribution, plasma kinetics, and utility as pulmonary vascular imaging agents. METHODS: Two ...
Eckle Tobias - - 2008
Although acute lung injury contributes significantly to critical illness, resolution often occurs spontaneously via activation of incompletely understood pathways. We recently found that mechanical ventilation of mice increases the level of pulmonary adenosine, and that mice deficient for extracellular adenosine generation show increased pulmonary edema and inflammation after ventilator-induced lung ...
Oshima Kiyohiro - - 2008
Thoracic esophagectomy for esophageal cancer is among the most invasive operations, requiring thoracotomy and laparotomy. With regard to postoperative status, the increment of vascular permeability caused by various inflammatory cytokines might influence the postoperative respiratory condition. The PiCCO (pulse contour cardiac output) system (Pulsion Medical Systems AG, Munich, Germany), a ...
Eguchi Takashi - - 2008
We report a case of pulmonary torsion of the lingula. Thoracoscopic segmentectomy of the left upper division was performed on a 67-year-old woman. The chest radiograph on the first postoperative day showed consolidation in the left apical area. By the second postoperative day, the consolidation had increased in size. Bronchoscopy ...
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