Search Results
Results 201 - 250 of 2216
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Naito Ryo - - 2011
Aortic dissection is a life-threatening cardiovascular disease with high in-hospital mortality. However, the risk factors of aortic dissection have not been fully elucidated. Obstructive sleep apnea (OSA) has been increasingly recognized as an independent cardiovascular risk factor. Among the underlying mechanisms to explain the association between OSA and cardiovascular morbidity, ...
Dellegrottaglie Santo - - 2011
BACKGROUND: Markers of collagen turnover have not been well studied in the context of cardiovascular disease in patients with chronic kidney disease (CKD). We investigated the associations between serum markers of collagen turnover [N-terminal procollagen type 3 propeptide (PIIINP) and carboxy-terminal telopeptide (C1TP)] and both pulse wave velocity (PWV) and ...
Monica Lind P - - 2011
BACKGROUND AND OBJECTIVE: Bisphenol A (BPA) levels have previously been associated with coronary heart disease (CHD). Since CHD is an atherosclerotic disease, we investigated if circulating levels of BPA and phthalate metabolites are related to atherosclerosis in a cross-sectional study. METHODS: In the population-based Prospective Investigation of the Vasculature in ...
Silva Liana Ferreira Alencar - - 2011
To study the distribution of the branches of the splenic artery and relate it to the radiological study of its intraparenchymal distribution, aiming to use this knowledge in partial splenectomy. In the macroscopic study, we used 60 human spleens which the splenic artery dissected from its origin to observe the ...
Tanasi C M - - 2011
This case has multiple anatomical variants of the inferior vena cava and its branches which determine the appearance of associated arterial abnormalities. The study has been performed on a female corpse, aged average 60, with no other morphological changes of the blood vessels or retroperitoneal viscera. The method we used ...
Wang T - - 2011
The mechanisms governing pulmonary gas exchange were heavily debated at the start of the 20th century when Christian Bohr provided measurements of lung and blood gases as well as rational arguments in favour of oxygen being secreted actively from the lung gas to the blood within vertebrate lungs. The concept ...
Donnelly J - - 2011
Nitric oxide (NO) is a potent vasodilator that regulates pulmonary vascular tone. During ascent to high altitude, pulmonary vascular tone increases leading to pulmonary hypertension. To explore the mechanisms underpinning this effect, we investigated the relationship between exhaled NO ( [Formula: see text] ; nmHg) and pulmonary artery systolic pressure ...
Park Hyun - - 2011
BACKGROUND: To describe preliminary experiences and the procedural details of retrieval thrombectomy using a self-expanding and fully retrievable Solitaire stent (ev 3 Inc., CA, USA) in acute ischemic stroke (AIS) patients with large artery occlusions. METHODS: Eight patients with AIS were treated by mechanical thrombectomy using a self-expanding, fully retrievable ...
Dodd Benjamin R - - 2011
Abdominal aortic aneurysm (AAA) is a common disease and a major cause of death through rupture, the risk of which increases with aneurysm size. There is approximately a 5 year interval from when aneurysmal dilatation develops until it reaches a size where surgery is indicated. Slowing, or arresting, aneurysm growth ...
Wedgwood Stephen S Department of Pediatrics, Division of Neonatology, Northwestern University Feinberg School of Medicine, 310 E. Superior St., Chicago, IL 60611, USA. - - 2011
We previously demonstrated that superoxide and H(2)O(2) promote pulmonary arterial vasoconstriction in a lamb model of persistent pulmonary hypertension of the newborn (PPHN). Because extracellular superoxide dismutase (ecSOD) augments vasodilation, we hypothesized that H(2)O(2)-mediated ecSOD inactivation contributes to pulmonary arterial vasoconstriction in PPHN lambs. ecSOD activity was decreased in pulmonary ...
Marks Joshua A - - 2011
Endovascular treatment of post-traumatic pseudoaneurysms has become a viable, less invasive option when compared to open repair. Due to the relative youth of this technology, studies have yet to be concluded on the long-term patency of stent grafts in this population. For this reason, concern exists with endovascular stent placement ...
Zhang Duan-Zhen - - 2011
Detection of pulmonary vasoreactivity is important for the evaluation of patient with pulmonary arterial hypertension (PAH). The present study aimed to investigate the acute hemodynamic responses to adenosine and iloprost in patients with congenital heart defects (CHDs) and severe PAH. From Mar 2007 to Nov 2009, 75 patients with severe ...
May-Newman Karen - - 2011
Aortic valve commissural fusion is a process in which fibrous tissue is deposited at the aortic valve commissures, creating adhesion between leaflets and preventing opening. Fusion has recently been associated with the implantation of left ventricular assist devices (VADs), affecting upwards of 50% of patients in recent studies. Aortic incompetence ...
Birincioglu Ismail - - 2011
There are few anatomical studies on hepatic vein compared to hepatic artery and portal vein. The aim of this study is to clarify the branching patterns of hepatic veins, supra and infra-diaphragmatic course of suprarenal inferior vena cava and its relation with the liver. Between March and May 2008, 103 ...
Gessler Tobias - - 2011
Inhaled treprostinil is a safe and well-tolerated approved pharmaceutical for the treatment of pulmonary arterial hypertension. In a series of open-label studies and in the pivotal trial with 253 patients, this long-acting prostacyclin analogue demonstrated pronounced pulmonary selectivity of vasodilatory effects, improved physical capacity and excellent tolerability and safety following ...
Székely Andrea - - 2011
Measurement of the global end-diastolic volume index (GEDI) by transpulmonary thermodilution (TPTD) has become a useful technique for measuring preload in adults. This study aimed to investigate the hemodynamic changes in neonates during the postoperative period after arterial switch surgery. Over a 13-month period, the postoperative data of 12 neonates ...
Neto-Neves Evandro M - - 2011
: Up-regulated matrix metalloproteinases may be involved in the development of cardiomyocyte injury and the degradation of troponin associated with acute pulmonary thromboembolism. We examined whether pretreatment with doxycycline (a nonspecific matrix metalloproteinase inhibitor) protects against cardiomyocyte injury associated with acute pulmonary thromboembolism. : Controlled animal study. : University research ...
George Joseph - - 2011
Pulmonary arterial hypertension (PAH) is characterized by intimal lesions, right ventricular hypertrophy, and adventitial thickening of pulmonary arteries with progressive pulmonary hypertension. This investigation was aimed to examine the effects of transgenic expression of human matrix metalloproteinase-9 (MMP-9) in the pathogenesis of PAH. PAH was induced using serial subcutaneous administration ...
Mehra Manik - - 2011
Objective To investigate the impact of coil design on the distribution of the coil mass in a controlled in vitro experiment. A secondary objective was to study the relationship between angiographic occlusion, packing density and coil mass uniformity. Methods Seven silicon side wall aneurysm models were embolized in each arm ...
Treumann Silke - - 2011
Dissecting aortic aneurysms, generally involving the thoracic aorta, have been shown to be caused by specific aliphatic amines in developing rats. Whether such lesions might occur spontaneously in control rats is not known. Therefore, in this study, 1,016 four-day-old, untreated rats culled from ongoing scheduled breeding studies were subjected to ...
Greene Arin K - - 2011
Vascular anomalies are disorders of the endothelium that can affect each part of the vasculature (capillaries, arteries, veins, or lymphatics). Although nearly always benign, vascular anomalies can involve any anatomic structure. Significant progress in understanding and treating patients with vascular anomalies has been made during the past quarter century since ...
Jusabani Ahmed - - 2011
Carotid artery stenosis is not thought to be a major cause of stroke in sub-Saharan Africa, though data are limited. The aim of this study was to use Duplex ultrasonography to establish the prevalence of significant carotid artery stenosis in an incident stroke population in Tanzania. Duplex ultrasound scan was ...
Potu B K - - 2011
The median artery is a transitory vessel that represents the arterial axis of the forearm during early embryonic life. It normally regresses in the second embryonic month. Its persistence in the human adult has been recorded in 2 different patterns: as a large, long vessel (palmar type) which reaches the ...
CelczyƄska Bajew Liliana - - 2011
Background: The incidence of coronary artery disease (CAD) and osteoporosis increases with age, especially in the elderly. Many studies have shown that vessel calcification is associated with low bone mineral density (BMD) and an increased risk of bone fractures. Experimental studies have shown that osteoprotegerin (OPG) gene knockout mice have ...
Payrau Bernard - - 2011
A first study on vascular fasciatherapy enabled us to observe the turning of a turbulent blood flow into a laminar one, and a questioning on the process involved in this transformation emerged. The first question was: What is the nature of artery from the point of view of fascia? And ...
Hasan Rani K - - 2011
South Asians are one of the highest risk ethnic groups for development of coronary artery disease (CAD) mortality and morbidity. Previous studies have investigated whether South Asians exhibit differences in angiographic coronary artery disease compared to Caucasians, with inconsistent results. We conducted a retrospective observational study comparing South Asians undergoing ...
Toprak Ahmet - - 2011
Conflicting information exists regarding the association between hsCRP and the progression of early stages of atherosclerosis. The purpose of the study was to investigate the association of high sensitiviy c-reactive protein (hsCRP) along with major cardiovascular (CV) risk factors on early carotid atherosclerosis progression in a large, population-based cohort study. ...
Johansson Elias P - - 2011
Directed ultrasonic screening for carotid stenosis is cost-effective in populations with > 5% prevalence of the diagnosis. Occasionally, calcifications in the area of the carotid arteries are incidentally detected on odontological panoramic radiographs. We aimed to determine if directed screening for carotid stenosis with ultrasound is indicated in individuals with ...
Su Ta-Chen - - 2011
Vegetarianism is associated with a lower risk of cardiovascular disease. However, studies of arterial function in vegetarians are limited. This study investigated arterial function in vegetarianism by comparing 49 healthy postmenopausal vegetarians with 41 age-matched omnivores. The arterial function of the common carotid artery was assessed by carotid duplex, while ...
Ruzsa Zoltán - - 2011
the clinical decision making could be difficult in patients with borderline lesions (visually assessed stenosis severity of 30 to 50%) of the left main coronary artery (LM). The aim of the study was to evaluate the relationship between transthoracic Doppler (TTDE) peak diastolic flow velocity (PDV) and intravascular ultrasound (IVUS) ...
Rabindranath Kannaiyan S - - 2011
A significant proportion of patients starting dialysis do so with a temporary or tunnelled haemodialysis catheter. Insertion of these catheters can be achieved either by using the anatomical landmarks for the veins into which they are inserted or using ultrasound guidance. It has been suggested that the use of ultrasound ...
Junker Christopher - - 2011
Arterial blood gases (ABG) are obtained commonly in dyspneic persons presenting to emergency departments. The study by Burri and colleagues found that the information contained in ABG fails to distinguish between pulmonary and other causes of dyspnea. On the other hand, arterial pH was highly predictive of ICU admission and ...
Honge Jesper L - - 2011
Glutaraldehyde-treated bioprosthetic heart valves are commonly used for replacement of diseased heart valves. However, calcification and wear limit their durability, and the development of new and improved bioprosthetic valve designs is needed and must be evaluated in a reliable animal model. We studied glutaraldehyde-treated valves 6 months after implantation to ...
Bridges Lakeesha E LE Julius L. Chambers Biomedical/Biotechnology Research Institute, North Carolina Central University, Durham, NC, - - 2011
Proximal resistance vessels, such as the mesenteric arteries, contribute substantially to the peripheral resistance. These small vessels of between 100-400 μm in diameter function primarily in directing blood flow to various organs according to the overall requirements of the body. The rat mesenteric artery has a diameter greater than 100 ...
Mantziari A A 1st Cardiolgoy Department, AHEPA Hospital, Aristotle University of Thessaloniki, Thessaloniki, - - 2011
Intravascular ultrasound (IVUS) has become a valuable tool adjunctive to coronary angiography due to its ability to directly image atheroma and the vessel wall. We aimed to evaluate the use of IVUS during diagnostic angiography and coronary interventions in a coronary intervention academic high volume center of northern Greece. IVUS ...
Keshavarz-Motamed Z Z Mechanical and Industrial Engineering, Concordia University, Montréal, Canada. - - 2011
Coarctation of the aorta is an obstruction of the aorta and is usually associated with other concomitant cardiovascular abnormalities especially with bicuspid aortic valve stenosis. The objectives of this study are, (1) to investigate the effects of coarctation on the hemodynamics in the aorta to gain a better understanding of ...
Filipovic Nenad N Faculty of Mechanical Engineering, University of Kragujevac, Sestre Janjica 6, 34000 Kragujevac, Serbia. - - 2011
Atherosclerosis develops from oxidized low-density lipoprotein molecules (LDL). When oxidized LDL evolves in plaque formations within an artery wall, a series of reactions occur to repair the damage to the artery wall caused by oxidized LDL. Macrophages accumulate inside arterial intima, they started to collect oxidized LDL and form foam ...
Sharif Dawod - - 2010
In the presence of severe stenosis, coronary artery flow may be reduced at rest. Recent advances in echocardiography have made non-invasive sampling of velocities in the left anterior descending coronary artery (LAD) possible. The aim of our study was to evaluate feasibility and capability of transthoracic Doppler to detect severe ...
O'Donnell C - - 2010
For patients with an atrial septal defect and pulmonary hypertension it can be difficult to determine whether it is safe to intervene. With newer treatments for pulmonary hypertension and transcatheter techniques avoiding surgical stressors, it has been hoped that we can occlude previously inoperable defects safely. We undertook a subgroup ...
Lu Xian-Ling - - 2010
It has been demonstrated that sildenafil is effective in patients with pulmonary arterial hypertension (PAH). However, the impact of sildenafil on PAH in adults with congenital heart disease (CHD) has been less investigated. In this prospective, open-label, uncontrolled and multicenter study, 60 patients with PAH related to CHD received oral ...
Hindocha Amit D - - 2010
To determine the relationship between the plane of occlusion and the Camper's line (ala-tragus line). Lateral cephalograms of 105 dentulous subjects were obtained after outlining the tragus and the base of the ala of the nose with radiopaque markers. Tracings of the cephalograms were done and the relationship between the ...
Vanderpool Rebecca R - - 2011
Hypoxic pulmonary hypertension (HPH) is initially a disease of the small pulmonary arteries. Its severity is usually quantified by pulmonary vascular resistance (PVR). Acute Rho kinase inhibition has been found to reduce PVR toward control values in animal models, suggesting that persistent pulmonary vasoconstriction is the dominant mechanism for increased ...
Gancel P-E - - 2011
Transcutaneous CO(2) monitors are widely used in neonatal ICUs. Until recently, these devices performed poorly in adults. Recent technical modifications have produced transcutaneous CO(2) monitors that have performed well in adults with chronic illnesses. We evaluated the accuracy of one of these devices, the TOSCA(®) 500, in adults admitted to ...
Willens Howard J - - 2010
A 39-year-old female had cor triatriatum (CT) detected as an incidental finding on transthoracic echocardiography performed to evaluate chest pain. By conventional two- and real time three-dimensional transesophageal echocardiography, the CT membrane had a communicating orifice connecting the accessory and main left atrial chambers that measured 1.3 × 0.8 cm. ...
Barst R - - 2010
Pulmonary arterial hypertension (PAH), characterized by increased pulmonary vascular resistance and pulmonary artery pressure, is a significant cause of morbidity and mortality in children and adults. Prior to 1995, there were no approved therapies for PAH. Review of the clinical drug development of epoprostenol (synthetic prostacyclin) for the treatment of ...
Gordon Brent M - - 2010
Staged palliative surgery is often required to regulate pulmonary and systemic blood flow in children with complex congenital heart disease. Accessory sources of pulmonary blood flow have been utilized to provide satisfactory pulmonary blood flow after Glenn anastomosis in select patients. Prolonged exposure to increased flow can lead to elevated ...
Dai Zen-Kong - - 2010
Endothelium-derived nitric oxide (NO) and endothelin (ET)-1 interact to regulate the vascular tone in pulmonary hypertension (PH). We investigated the protective effects of an orally active, dual endothelin converting enzyme (ECE)/neutral endopeptidase (NEP) inhibitor/CGS 26393 on pulmonary vascular remodeling and pulmonary expressions of ET-1 and endothelial nitric oxide synthase (eNOS) ...
Rich Stuart - - 2010
The current treatment of pulmonary arterial hypertension (PAH) uses vasodilator drugs. Although they improve symptoms associated with PAH, their chronic effects on the pulmonary vasculature and the right ventricle (RV) in humans remain unknown. We report the autopsy findings from a patient with idiopathic PAH treated with epoprostenol successfully for ...
Russell Hyde M - - 2011
A common arterial trunk is a solitary trunk that exits the heart through a common ventriculo-arterial junction and supplies directly the systemic, pulmonary, and coronary arterial pathways. It remains to be determined, however, how best to subclassify those hearts fulfilling this definition. The time-honored classification is based on the morphology ...
Palecek Tomas - - 2011
The differentiation between chronic pulmonary thromboembolic hypertension (CTEPH) and pulmonary arterial hypertension (PAH) remains a clinical challenge. The aim of our study was to evaluate the usefulness of both echocardiographically and invasively derived pulmonary artery pulsatility indexes in the etiologic differentiation of patients with CTEPH and PAH. We retrospectively analyzed ...
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