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Forte Amalia A *Department of Experimental Medicine, Second University of Naples, Via L. De Crecchio 7, 80138 Naples, - - 2014
Restenosis is the pathophysiological process occurring in 10-15% of patients submitted to revascularization procedures of coronary, carotid and peripheral arteries. It can be considered as an excessive healing reaction of the vascular wall subjected to arterial/venous bypass graft interposition, endarterectomy or angioplasty. The advent of bare metal stents, drug-eluting stents ...
Zimlichman Reuven R Department of Medicine and Hypertension Unit, the Brunner Institute for Cardiovascular Research, Sackler Faculty of Medicine, Tel Aviv University and The E. Wolfson Medical Center, P.O.B. 5, 58100, Holon, Israel, - - 2014
Cardiovascular risk factors (CVRFs) have been shown to induce end organ damage. Until now, the main approach to reduce CVRF-induced end organ damage was by normalization of CVRFs; this approach was found effective to reduce damage and cardiovascular (CV) events. However, a residual risk always remained even when CVRFs were ...
Stehouwer Marco C MC Department of Extracorporeal Circulation, St Antonius Hospital, Nieuwegein - The - - 2014
Introduction of gaseous microemboli (GME) into the arterial line of a pediatric cardiopulmonary bypass (CPB) circuit may lead to cognitive decline and adverse outcomes of the pediatric patient.Arterial filters are incorporated into CPB circuits as a safeguard for gross air and to reduce GME. Recently, arterial filters were integrated in ...
Verelst Wim W Department of Critical Care - - 2014
The simultaneous occurrence of subcutaneous emphysema and intravascular air due to an air embolism is a rare condition. Here, we report a patient with COPD who developed a severe episode of hemoptysis due to rupture of a previously undiagnosed lung cavern. Intubation and ventilation led to the development of both ...
Baltsavias Gerasimos G Department of Neuroradiology, University Hospital Zurich; Zurich, Switzerland - - - 2014
The anastomotic network of the posterior circulation in children with moyamoya disease has not been analyzed. We aimed to investigate the angiographic anatomy of this unique vascular network in patients with childhood moyamoya disease. Selective and superselective injections of the posterior circulation were performed in six children with newly diagnosed ...
Güngör Olcay O Department of Pediatric Neurology, Faculty of Medicine, Kahramanmaras Sutcu Imam University, Kahramanmaras, Turkey - - 2014
Headache is one of the common symptoms of intracranial aneursym. A 5-year-old child lately presented to our pediatric emergency department with persistent headache. Brain magnetic resonance imaging revealed a 7×8 mm rounded lesion with slowly heterogeneous low signal in T2 sequence consistent with a partial occluded aneurysm, in the right ...
Nicolarsen Jeremy J Department of Pediatrics, University of Colorado and Children's Hospital Colorado, Aurora, Colorado, - - 2014
Pulmonary hypertension is a complex disease that extends beyond merely elevated pulmonary blood pressures and right ventricular dysfunction. Its multiple causes and ever-expanding diagnostic tools and therapeutic approaches make it a heterogeneous disease with widely variable clinical sequelae. There are still many unanswered questions that challenge our understanding of this ...
Nowosławska Emilia E Polish Mother's Memorial Hospital Research Institute, Rzgowska st 289/281, 93-338, Łódź, Poland, - - 2014
The aim of the article is to present the new hybrid technique for ventriculoatrial shunt implantation. Two-and-a-half-year-old boy needed ventriculoatrial shunt implantation due to communicating hydrocephalus and impaired absorptive ability of the peritoneum. Because of a complete occlusion of the right internal jugular vein and critical stenosis of a distal ...
Tromp Gerard G The Sigfried and Janet Weis Center for Research, Geisinger Health System , Danville, Pennsylvania , - - 2014
Intracranial aneurysms, also called cerebral aneurysms, are dilatations in the arteries that supply blood to the brain. Rupture of an intracranial aneurysm leads to a subarachnoid hemorrhage, which is fatal in about 50% of the cases. Intracranial aneurysms can be repaired surgically or endovascularly, or by combining these two treatment ...
Wall Michael L ML Department of Vascular Surgery, Worcestershire Acute Hospitals NHS Trust, Worcester Royal Hospital, Charles Hasting Way, Worcester, WR5 1DD. Electronic address: - - 2014
Supra-coeliac abdominal aortic dissections are rare and require complex interventions for repair. Superior mesenteric artery (SMA) dissections are also rare and even less frequently reported to involve aneurysmal change. We present the case of a 65 year-old man with a dissecting supra-coeliac aorto-iliac aneurysm and a separate dissecting aneurysm of ...
Kang Jun Ren JR Department of Parenteral and Enteral Nutrition, Peking Union Medical College Hospital, Chinese Academy Of Medical Sciences and Peking Union Medical College, Beijing, - - 2014
We read with great interest the recently published paper by Chopra V et al. [1], on peripherally inserted central catheter-related deep vein thrombosis. As the authors point out, recent diagnosis of cancer and PICC gauge are associated with PICC associated deep vein thrombosis (DVT). This conclusion is consistent with previous reports ...
Alsac Jean-Marc JM Hopital Europeen Georges Pompidou, Paris, France. Electronic address: - - 2014
Chimney endovascular aneurysm repair (EVAR) is still a controversial treatment of complex aortic aneurysms. Stentgrafts patency and type I endoleaks are the main challenges that temper this bail out technique. Endovascular aneurysm sealing (EVAS) consists of anchoring and sealing the device within the aneurysm sac. First results are promising, even ...
Siemelink Marten Antoon MA Laboratory of Experimental Cardiology, University Medical Center Utrecht, Heidelberglaanes 100 Room G02.523, PO Box 85500, 3508 GA, Utrecht, The Netherlands, - - 2014
The last years have witnessed tremendous technical advances in the field of transcriptomics that enable the simultaneous assessment of nearly all transcripts expressed in a tissue at a given time. These advances harbor the potential to gain a better understanding of the complex biological systems and for the identification and ...
Lee Jake J JJ School of Medicine, University of Pittsburgh, Pittsburgh, - - 2014
Thoracic aortic diseases are life-threatening conditions causing significant mortality and morbidity despite advances in diagnostic and surgical treatments. Computational methods combined with imaging techniques provide quantitative information of disease progression, which may improve clinical treatments and therapeutic strategies for clinical practice. Since hemodynamic and wall mechanics play important roles in ...
Esfahani Darian R - - 2014
Until recently, endovascular management of intracranial aneurysms has focused on mechanical and hemodynamic aspects: characterizing aneurysm morphology by angiogram, mechanical obstruction by detachable coils, and flow diversion with endovascular stents. Although now common practice, these interventions only ward off aneurysm rupture. The source of the problem, disease of the vessel ...
Lv Bing-Jie BJ Laboratory of Cardiovascular Immunology, Institute of Cardiology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430022, - - 2014
Aortic aneurysms are common and life threatening problems with high rates of death. The initiation and progression of aneurysms are characterized by extensive extracellular matrix degradation and immune cells invasion within arterial wall. During the pathogenesis of all aneurysms, inflammation and immune cells play a significant role. Although T cells ...
Gutsche Jacob T JT Department of Anesthesiology and Critical Care, Perelman School of Medicine, University of Pennsylvania, Philadelphia, - - 2014
There is currently a paradigm shift in the conduct of adult aortic arch repair. Although deep hypothermic circulatory arrest has been the classic perfusion platform for adult aortic arch repair, recent developments have challenged this aortic arch paradigm. There has been a gradual clinical drift towards moderate, and even mild, ...
Bruggink J L JL Department of Surgery (Division of Vascular Surgery), University Medical CenterGroningen, University of Groningen, Groningen, the Netherlands - - - 2014
Mesenteric ischemia after abdominal aneurysm repair is a devastating complication with mortality rates up to 70%. Incidence however is relatively low. The aim of this review is to provide an overview on current insights, diagnostic modalities and on mesenteric ischemia after abdominal aortic aneurysm repair.
Yamawaki-Ogata Aika A Aika Yamawaki-Ogata, Xian-Ming Fu, Akihiko Usui, Yuji Narita, Department of Cardiac Surgery, Nagoya University Graduate School of Medicine, Nagoya 466-8550, - - 2014
An aortic aneurysm (AA) is a silent but life-threatening disease that involves rupture. It occurs mainly in aging and severe atherosclerotic damage of the aortic wall. Even though surgical intervention is effective to prevent rupture, surgery for the thoracic and thoraco-abdominal aorta is an invasive procedure with high mortality and ...
Davis Frank M FM Saha Cardiovascular Research Center, University of Kentucky, Lexington, Kentucky, - - 2014
Aneurysms are common in the abdominal and thoracic regions of the aorta. While generally asymptomatic, progression of aneurysms is associated with the devastating consequences of aortic rupture. Current therapeutic options to prevent rupture are restricted to surgical repair, as there remains a lack of validated pharmaceutical approaches. Absence of proven ...
Lin Albert A aDepartment of Medicine bDepartment of Medicine, Division of Cardiology, Alpert Medical School of Brown University, Rhode Island Hospital, Providence, Rhode Island, - - 2014
A pseudoaneurysm of the mitral-aortic intervalvular fibrosa is a rare but potentially fatal complication seen primarily in the context of infective endocarditis. In this study, we discuss a case of infective endocarditis that was complicated by the rupture of a pseudoaneurysm of the mitral-aortic intervalvular fibrosa. We review the salient ...
Rosi Junior Jefferson J Hospital das Clínicas, da Faculdade de Medicina, Division of Neurological Surgery, School of Medicine, University of Sao Paulo, Rua Eneas C Aguiar, 255, Sao Paulo, SP, - - 2014
Cavernous carotid aneurysms (CCA) account for 2-9% of all intracranial aneurysms. They have been considered benign lesions, most often asymptomatic, and to have a natural history with a low risk of life-threatening complications. These aneurysms are unique, their rupture can present in many different forms, they can suffer spontaneous thrombotic ...
Dou Ning-Ning - - 2014
Although neurovascular confliction was believed to be the cause of hemifacial spasm (HFS), the mechanism of the disorder remains unclear to date. Current theories, merely focusing on the facial nerve, have failed to explain the clinical phenomenon of immediate relief following a successful microvascular decompression surgery (MVD). With the experience ...
Wang Yutang Y The Vascular Biology Unit, Queensland Research Centre for Peripheral Vascular Disease, School of Medicine and Dentistry, James Cook University, Townsville, Queensland 4811, - - 2014
Subarachnoid hemorrhage secondary to rupture of an intracranial aneurysm is a highly lethal medical condition. Current management strategies for unruptured intracranial aneurysms involve radiological surveillance and neurosurgical or endovascular interventions. There is no pharmacological treatment available to decrease the risk of aneurysm rupture and subsequent subarachnoid haemorrhage. There is growing ...
Tullius Thomas G TG Jr Paul L. Foster School of Medicine, Texas Tech University Health Sciences Center, El Paso, TX, - - 2014
Arteriovenous malformations (AVM) of the uterus can cause life-threatening hemorrhage. Unexplained, heavy vaginal bleeding in a reproductive age woman should raise suspicion for an AVM. Here a 37-year-old woman had increasingly severe vaginal bleeding for 15 days. Serum β-hCG was elevated. Two-dimensional transvaginal ultrasound suggested retained products of conception. Before ...
Spentzouris Georgios G Department of Anatomical Sciences, School of Medicine, St. George's University, St. George's, Grenada, West - - 2014
Anomalies in the course and drainage of the Inferior Vena Cava (IVC) may complicate normal functioning, correct diagnosis, and therapeutic interventions within the abdomen. Development of the IVC occurs during the 4th to 8th week of gestation, and due to its developmental complexity, there are many opportunities for malformations to ...
Nakamura Yuichi Y Department of Cardiology and Hematology, Fukushima Medical - - 2014
An 82 years-old man with intermittent claudication was admitted to our hospital. Computed tomography angiography showed his right superficial femoral artery (SFA) was chronic total occlusion (CTO), and we performed endovascular treatment (EVT). We advanced a guide-wire by contralateral transfemoral approach, but guide-wires could not penetrate the occluded SFA lesion ...
Zhao Junjie - - 2014
Stroke or cerebral vascular accidents is among the leading causes of death in the world. With the availability of Digital Subtraction Angiography, transluminal angioplasty has become feasible in many situations and the role of intracranial stents is becoming ever more important in the management of cerebral vascular diseases. In current ...
Salmasi Shima - - 2014
Intracranial aneurysms are present in 1-5% of population and can be described as "ticking time bombs" that can go off at any time and cause serious harms including permanent disability and death. There are two routinely practiced treatment options for this disease; endovascular coiling and surgical clipping. In recent years ...
Jardim Carlos C Pulmonary Circulation Unit, Pulmonary Division, Heart Institute, University of Sao Paulo Medical School, Sao Paulo, - - 2014
To understand the rational of establishing a goal-oriented therapy for pulmonary arterial hypertension management. During the last decades, the development of targeted therapies and the recognition of prognostic markers represented a major step for improving pulmonary arterial hypertension survival. Now, changing the strategy on using these compounds therapies might represent ...
Dickinson Michael G MG Center for Congenital Heart Diseases, Department of Pediatric Cardiology, Beatrix Children's Hospital and Laboratory CardioVascular Center, GUIDE, University Medical Center Groningen, University of Groningen, the - - 2014
Pulmonary arterial hypertension (PAH) is characterized by development of unique neointimal lesions in small pulmonary arteries, leading to increased right ventricular (RV) afterload and -failure. Novel therapeutic strategies are needed that target these neointimal lesions. Recently, the transcription factor Egr-1 was demonstrated to be upregulated early in experimental neointimal PAH. ...
Birns Jonathan J Department of Ageing & Health, St Thomas' Hospital, London, United Kingdom; Department of Stroke Medicine, King's College Hospital, London, United Kingdom. Electronic address: - - 2014
Following the development of intravenous thrombolysis as a successful treatment for ischaemic stroke, advances in neurointerventional radiology have facilitated endovascular approaches to treatment. This article reviews the available endovascular therapeutic options and their evidence-base. Initial studies demonstrated that endovascular treatment of ischaemic stroke with intra-arterial thrombolysis and/or the use of ...
Dias N V NV Vascular Center, Skånes University Hospital, Malmö, Sweden - - - 2014
This article reviews the solutions for the revascularization of the left subclavian artery during TEVAR. Open surgical revascularization has been the predominant technique used but recent developments may lead to an increasing role of the endovascular revascularization. The different open and endovascular technical options are discussed and the results summarized.
LeFevre Michael L - - 2014
Update of the 2007 U.S. Preventive Services Task Force (USPSTF) recommendation on screening for carotid artery stenosis. The USPSTF commissioned a systematic review to synthesize the evidence on the accuracy of screening tests, externally validated risk stratification tools, the benefits of treatment of asymptomatic carotid artery stenosis with carotid endarterectomy ...
Pérez-Riera Andres Ricardo AR Cardiology Discipline, ABC Medical Faculty, ABC Foundation, Santo André, São Paulo, - - 2014
A 44-year-old man with aortic valve insufficiency and stenosis underwent aortic valve replacement depicting interesting ECG changes. This unique case is discussed, contributing to the understanding of a trifascicular left intraventricular conduction system.
Buell Thomas J TJ University of Virginia, Department of Neurosurgery, P.O. Box 800212, Charlottesville, VA 22908, USA. Electronic address: - - 2014
Endovascular occlusion of cerebral arteriovenous malformations (AVM) is often utilized as adjunctive therapy in combination with radiosurgery or microsurgery. Evidence supports that partial occlusion of AVM via endovascular embolization leads to increased angiogenesis. This phenomenon may be a contributing factor to the decreased efficacy of AVM radiosurgery following embolization. We ...
Fineschi Massimo M Department of Cardiovascular Diseases, University Hospital Santa Maria alle Scotte, Siena, Italy *Massimo Fineschi and Flavio D'Ascenzi contributed equally to the writing of this - - 2014
Angiographic diagnosis and treatment of spontaneous coronary artery dissection is challenging. Complementary use of intracoronary imaging can provide information to guide percutaneous treatments, particularly in these challenging settings. Here we report a case of a 52-year-old woman presenting with an anterior ST-segment elevation myocardial infarction caused by a spontaneous, long, ...
Sizarov Aleksander A Center for Congenital Heart Defects, UMC Groningen, Netherlands - - 2014
To provide comprehensive illustrations of anatomy of the relevant vessels in large experimental animals in an interactive format as preparation for developing an effective and safe transcatheter technique of aortopulmonary and bidirectional cavopulmonary intervascular anastomoses. Computed tomographic angiographic studies in two calves and two sheep were used to prepare 3D ...
Nossek Erez E Department of Neurosurgery, Hofstra North Shore-Long Island Jewish School of Medicine, and North Shore-Long Island Jewish Health System, Manhasset, New York, - - 2014
Postoperative drawings of aneurysms serve as visual records and teaching tools for neurosurgeons and reinforce 3D vascular configurations that are specific for different cerebral aneurysms. This report brings this time-honored tradition back into focus in the digital era, and examines our experience with this technique, particularly in respect to the ...
Pancholy Samir B SB The Wright Center for Graduate Medical Education, The Commonwealth Medical College, Scranton, PA, USA, - - 2014
Radial artery occlusion (RAO) is the most common structural consequence of transradial access (TRA) with an estimated incidence ranging from 2-10 %. Its occurrence is free of any major clinical consequences, especially at rest, with most if not all cases of digital ischemia occurring as a result of embolization, rather than ...
Chatterjee Soumya S Department of Rheumatic and Immunologic Diseases, Orthopedic and Rheumatology Institute, Cleveland Clinic, 9500 Euclid Avenue, Desk A50, Cleveland, OH, 44195, USA, - - 2014
Takayasu arteritis (TA) is 1 of the 2 main causes of large vessel vasculitides (LVV), giant cell arteritis being the other. LVV can also develop in various other systemic diseases. In TA, a wide variety of symptoms result from vascular stenoses, occlusions, and dilation. Aneurysms may develop and may occasionally ...
Goubergrits Leonid L Biofluid Mechanics Laboratory, Charité-Universitätsmedizin Berlin, Augustenburger Platz 1, 13353 Berlin, - - 2014
Coils and flow diverters or stents are devices successfully used to treat cerebral aneurysms. Treatment aims to reduce intra-aneurysmal flow, thereby separating the aneurysmal sac from the blood circulation. The focus and this manuscript combining literature review and our original research is an analysis of changes in aneurysmal hemodynamics caused ...
Gorla Riccardo R aCardiology Clinic and University of Insubria, Ospedale di Circolo e Fondazione Macchi, Varese bCardiology and Coronary Intensive Care Unit, IRCCS San Raffaele Hospital and Vita-Salute San Raffaele University, Milan, - - 2014
Drug-eluting stents (DESs) are known to reduce in-stent restenosis rate, compared with bare metal stents (BMSs). Stent thrombosis, one of the most dangerous complications of DES, has emerged as a major concern. This issue has limited the use of DES in unstable coronary artery disease till recent years. In fact, ...
Wollersheim Laurens W LW Department of Cardiothoracic Surgery, Academic Medical Center, University of Amsterdam, Amsterdam, The - - 2014
In this review, we discuss the current surgical treatment for aortic valve stenosis. Surgical strategy for treatment of aortic valve stenosis is based on the risk profile of the patient. We reviewed the existing literature and present the current state of the art of these various approaches, taking into account ...
George Isaac I Division of Cardiothoracic Surgery, Columbia College of Physicians and Surgeons, New York Presbyterian Hospital, New York, New York. Electronic address: - - 2014
We describe our experience using the Edwards Sapien transfemoral Retroflex 3 catheter delivery system for transcatheter aortic valve replacement through the transapical and transaortic approaches. Transthoracic transcatheter valve replacement by the transapical and transaortic approaches can be safely and effectively performed with the Retroflex 3 delivery catheter, which affords several ...
Mokin Maxim M Department of Neurosurgery, School of Medicine and Biomedical Sciences, University at Buffalo, State University of New York, Buffalo, NY, USA; Department of Neurosurgery, Gates Vascular Institute, Kaleida Health, Buffalo, NY, - - 2014
Endovascular intra-arterial therapy is reserved for strokes from large vessel occlusion. This article reviews the critical role of the location of the occlusion, extent and characteristics of the occlusive thrombus on noninvasive imaging, and identification of ischemic core and salvageable tissue on perfusion imaging for proper patient selection. The advantages ...
Baggott Christopher D CD Department of Neurological Surgery, University of Wisconsin Hospital and Clinics, 600 Highland Avenue, Madison, WI 53792, - - 2014
Cerebral vasospasm causes delayed ischemic neurologic deficits after aneurysmal subarachnoid hemorrhage. This is a well-established clinical entity with significant associated morbidity and mortality. The underlying patholphysiology is highly complex and poorly understood. Large-vessel vasospasm, autoregulatory dysfunction, inflammation, genetic predispositions, microcirculatory failure, and spreading cortical depolarization are aspects of delayed neurologic ...
Eller Jorge L JL Department of Neurosurgery, University at Buffalo, State University of New York, Buffalo, NY, USA; Department of Neurosurgery, Gates Vascular Institute, Kaleida Health, Buffalo, NY, USA; Cerebrovascular Neurosurgery, PeaceHealth Sacred Heart Medical Center, 333 Riverbend Drive, Springfield, OR 97477, - - 2014
Carotid artery angioplasty and stenting (CAS) has experienced an astonishing rate of development over the last 2 decades, becoming a viable alternative to carotid endarterectomy (CEA) in the management of carotid stenosis. Many trials have attempted to compare both treatment modalities and establish indications for each, depending on clinical and ...
Serrone Joseph C JC Department of Neurosurgery, UC College of Medicine, Cincinnati, OH, - - 2014
Unlike saccular or berry aneurysms, which present more often with subarachnoid hemorrhage, fusiform aneurysms present more often with ischemic stroke or mass effect. The most time-tested treatment of fusiform vertebrobasilar aneurysms consists of flow reduction or flow reversal. Recently, flow diversion has been attempted with mixed results in the posterior ...
Hadjimiltiades Stavros S Department of Cardiology, AHEPA University Hospital, Thessaloniki, - - 2014
We describe the successful closure of an aortic paravalvular bioprosthetic valve leak with the simultaneous percutaneous deployment of two vascular plugs.
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