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Results 401 - 450 of 1745
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Yano Motoki - - 2013
OBJECTIVESThe use of staplers for thoracic surgery has been widely accepted and regarded as a safe procedure. However, adverse events (AEs) of stapling are occasionally experienced. The aim of this retrospective study was to analyse the AEs of stapling in pulmonary vascular surgery.METHODSA retrospective multi-institutional review was conducted by the ...
Ho Paul C - - 2013
A percutaneous temporary aortic valve hemodynamic support catheter is a device that can conceptually maintain stable hemodynamics when significant structural damage occurs to the native aortic valve ensuing acute severe aortic insufficiency. Applications may include a bridge to surgery in active aortic valve endocarditis and an option to allow for ...
Donadini Marco P - - 2013
Introduction: Several low-molecular-weight heparins are available for the prevention and treatment of venous thromboembolism and arterial thrombosis. Certoparin has been extensively tested in different clinical settings for about 20 years. Areas covered: The authors provide a drug evaluation based on literature searches performed through Medline. Specifically, the authors review studies ...
Dempsie Yvonne - - 2013
Pulmonary arterial hypertension (PAH) is a progressive disease in which increased pulmonary arterial pressure and remodelling eventually lead to right heart failure and death. Idiopathic and familial PAH occur far more frequently in women than in men. Historically, investigations into this gender bias have been impeded as female gender and ...
Goodwin Meredith Rumon - - 2013
Advances in the surgical approach to thoracic aortic aneurysm repairs have led to the increasing use of one-lung ventilation. Today's practice of cardiothoracic and vascular anesthesia requires a clear understanding of the techniques available for lung separation and the technical skills necessary to employ them. In this article, we discuss ...
Mourani Peter M - - 2013
PURPOSE OF REVIEW: Pulmonary hypertension contributes significantly to morbidity and mortality of chronic lung disease of infancy, or bronchopulmonary dysplasia (BPD). Advances in pulmonary vascular biology over the past few decades have led to new insights into the pathogenesis of BPD; however, many unique issues persist regarding our understanding of ...
Payvandi Laila A - - 2013
The mitral valve annulus is a complex structure that is an integral part of the mitral valve apparatus. The annulus plays an active role in mitral valve leaflet coaptation and in left atrial and ventricular function. The annulus is susceptible to disease processes that are distinct from those that affect ...
Taheri Morteza Sanei - - 2013
Abdominal aortic aneurysms (AAAs) are defined as abnormal dilatation of the abdominal aorta and are potential to catastrophic complications. With the advent of multidetector computed tomography (MDCT), this diagnostic modality has virtually replaced conventional angiography in many circumstances and has become an integral part of the evaluation of AAA. Its ...
Gao Liangbin - - 2013
BACKGROUND CONTEXT: The understanding of vascular supply to the spinal cord is important given that the evolution of surgical approaches to the spine may bring along the potential for more frequent complications, especially a rare but devastating complication: that of spinal cord ischemia or infarction. To maximally avoid this complication, ...
Healy Helen - - 2013
Case 1. The Distressed Health Care Provider Mr MF was a 72 yo married father living independently with his wife. Mr MF was admitted electively for non-operative correction of a known left renal artery stenosis. Previous investigations reported two small kidneys with total obstruction of the right renal artery and ...
Habib Nicholas - - 2013
Gastroduodenal artery (GDA) aneurysms are rare but a potentially fatal condition if rupture occurs. They represent about 1.5% of all visceral artery (VAA) aneurysms and are divided into true and pseudoaneurysms depending on the etiologic factors underlying their development. Atherosclerosis and pancreatitis are the two most common risk factors. Making ...
Channick Richard N - - 2013
Many potential therapeutic options are now available for patients with pulmonary arterial hypertension. Interest has emerged in using therapies in various combinations. Retrospective experience has suggested that this approach is common and can be efficacious. Data are emerging supporting the benefit of combination therapy; however, limitations and questions remain about ...
Dal-Bianco Jacob P - - 2013
The mitral valve apparatus is a complex 3-dimensional (3D) functional unit that is critical to unidirectional heart pump function. This review details the normal anatomy, histology, and function of the main mitral valve apparatus components: mitral annulus, mitral valve leaflets, chordae tendineae, and papillary muscles. Two-dimensional and 3D echocardiography is ...
Liu Yuanming Y Department of Mechanical Engineering, University of Washington, Seattle, Washington 98195-2600, - - 2013
Elastin is an intriguing extracellular matrix protein present in all connective tissues of vertebrates, rendering essential elasticity to connective tissues subjected to repeated physiological stresses. Using piezoresponse force microscopy, we show that the polarity of aortic elastin is switchable by an electrical field, which may be associated with the recently ...
Wunderlich Nina C - - 2013
Transesophageal echocardiography is routinely used to guide percutaneous interventions involving the mitral valve. Mitral balloon valvuloplasty for rheumatic mitral valve stenosis (MS) was the first percutaneous intervention to gain wide acceptance. New techniques have been developed to treat degenerative and functional mitral regurgitation (MR) as well as paravalvular mitral leak ...
Lopez-Benitez Ruben - - 2013
We describe a new, useful embolization technique applied to occlude narrow vessel branches (≤1.5 mm (0.06″) in diameter) by deployment of one hydrocoil, through a microcatheter, in a way similar to the way in which one might navigate through the vascular lumen with a guidewire.
Ambekar Sudheer - - 2013
Stents have come to be well-known devices and are being used widely in numerous branches of medicine. It is intriguing that the word "stent" actually derives from the name of a dentist, Charles Stent, who developed a material to obtain dental impressions. There are numerous other theories as to the ...
Nadkarni Nikhil A - - 2013
Pancreatitis is an inflammatory process with local and systemic manifestations. One such local manifestation is thrombosis in splanchnic venous circulation, predominantly of the splenic vein. The literature on this important complication is very sparse. This review offers an overview of mechanism of thrombosis, its pathophysiology, diagnosis, and management in the ...
Rajfer J - - 2013
Endothelial dysfunction, a marker for atherosclerosis and hence arterial disease, has recently been proffered as the main offender within the vascular system to predict not only the future onset of erectile dysfunction (ED) but also as the main cause of the ED. To glean more insight into whether arterial disease ...
Shimamura Munehisa - - 2013
The effectiveness of angioplasty and stenting in intracranial atherosclerotic diseases is controversial due to high rates of delayed restenosis and hemorrhage compared with extracranial arteries. However, the mechanisms underlying these differences are still unclear, because their pathophysiology is yet to be examined. To address this issue, we established a novel ...
Puri Rishi - - 2013
Coronary angiography has been widely used for five decades to evaluate a range of vascular pathologies and triage patients to therapeutic interventions. The inability to directly visualize the artery wall with conventional angiographic techniques has stimulated development of a number of intravascular imaging modalities. These approaches have the potential to ...
Balasubramaniyam Nivas - - 2013
The practice of intravascular stenting largely grew out of the concept of stenting the coronaries in acute myocardial infarction. According to the recent United States Renal Data System data registry, there has been a significant increase in endovascular intervention (1.8-fold increase-from 52,380 to 98,148) with a 2.2-fold increase in stent ...
Vijaynagar Badri - - 2013
OBJECTIVE: Abdominal aortic aneurysm (AAA) is a condition that mainly affects elderly men. At present, there is no effective medical therapy that can retard aneurysm growth or prevent aneurysm rupture. There is evidence that angiogenesis within the wall of an aortic aneurysm may play key roles in aneurysm progression as ...
Indes Jeffrey E - - 2013
Evaluation of: Lederle FA, Freischlag JA, Kyriakides TC et al.; OVER Veterans Affairs Cooperative Study Group. Long-term comparison of endovascular and open repair of abdominal aortic aneurysm. N. Engl. J. Med. 367(21), 1988-1997 (2012). The traditional method of treating abdominal aortic aneurysms with open surgical repair has been steadily replaced ...
Chandra Sharad - - 2013
The retrograde approach using collaterals has been introduced for percutaneous dilatation and opening of chronic total occlusion of the coronary arteries. The controlled antegrade and retrograde tracking (CART) strategy has been developed to improve guidewire crossing and successful recanalization. We herein describe a case of left anterior descending chronic total ...
Wilson Steve - - 2013
Endovascular repair of AAAs has been embraced by the vascular surgery community. Fenestrated endovascular repair of AAAs is the logical next step to repairing those aneurysms whose anatomy does not provide a secure landing area for the graft below the renal and other visceral vessels. While the early morbidity and ...
Al Aloul Basel - - 2013
New techniques involving the use of retrograde channels have enabled successful revascularization of chronically occluded arteries previously not amenable to standard strategies. We describe the use of a simultaneous antegrade and retrograde approach to perform bifurcation kissing balloon angioplasty which was not possible using a standard antegrade approach. As the ...
Cristofaro Brunella - - 2013
Arteriogenesis requires growth of pre-existing arteriolar collateral networks and determines clinical outcome in arterial occlusive diseases. Factors responsible for the development of arteriolar collateral networks are poorly understood. The Notch ligand Delta-like 4 (Dll4) promotes arterial differentiation and restricts vessel branching. We hypothesized that Dll4 may act as a genetic ...
Shinbane Jerold S - - 2013
Cardiovascular computed tomographic angiography (CCTA) provides an understanding of the three-dimensional (3D) coronary artery anatomy in relation to cardiovascular thoracic structures important to the surgical management of anomalous coronary arteries (ACAs). Although some ACA variants are not clinically significant, others can lead to ischemia/infarction, related acute ventricular dysfunction, ventricular arrhythmias, ...
Wasilewski Jarosław - - 2013
Thoracic aortic calcium deposits are frequently detected on tomography of the chest, and in other imaging modalities. Numerous studies indicated the correlation of hemodynamic parameters such as wall shear stress in relation to distribution aortic calcifications. This publication discusses similarities and differences of two distinct pathomechanisms of arterial calcifications: intimal ...
Austin Eric D - - 2013
Most subtypes of pulmonary arterial hypertension (PAH) are characterized by a greater susceptibility to disease among females, although females with PAH appear to live longer after diagnosis. While this "estrogen paradoxȍ of enhanced female survival despite increased female susceptibility remains a mystery, recent progress has begun to shed light upon ...
Muthialu Nagarajan N Department of Cardiothoracic Surgery, Great Ormond Street Hospital for Children NHS Trust, London, - - 2013
Combined tracheobronchial and thoracic vascular injury in children following blunt trauma to the chest is potentially life-threatening and almost certain to be fatal unless managed promptly. We report one such incident where prompt identification and early aggressive surgical management prevented an almost certain fatal outcome in a 5-year-old girl with ...
Green Kelly D KD Vanderbilt Heart and Vascular Institute, Nashville, TN 37232-8802, - - 2013
Hybrid coronary revascularization combines the benefits of both percutaneous coronary intervention (PCI) and coronary artery bypass grafting (CABG) in the treatment of multivessel coronary artery disease (CAD) by combining the benefits of the LIMA-to-LAD graft and drug eluting stent (DES) to non-LAD regions. Through this approach, a patient receives the ...
Rothuizen Tonia C - - 2013
Haemodialysis vascular access patency is severely compromised by fistula non-maturation and access stenosis. Intimal hyperplasia (IH) is considered the culprit lesion in failed fistulas, resulting in luminal narrowing and stenosis. This review focuses on the biology and pathophysiology of fistula failure and highlights not only the classically associated IH but ...
Takahashi Hiroaki - - 2013
Although median sternotomy is the accepted approach to the heart for cardiac surgery, minimally invasive approaches including partial sternotomies have recently been developed. However, such strategies might lead to sternal overriding, instability, and fracture or division of the internal thoracic arteries. Furthermore, a full sternotomy would be required to address ...
Sinzinger Helmut - - 2013
Ventilation/perfusion scintigraphy is the diagnostic tool of choice for detection and monitoring of pulmonary embolism. However, the knowledge on its value for other or concurrent pathologies is poor. In this review scintigraphic characteristics of the main pathologies, interpretation and artefacts are described. Together with the understanding of pathophysiology of the ...
Schleh Carsten - - 2013
The article of Gasser et al. [Part Fibre Toxicol. 24; 9:17, 2012] describes the interaction of carbon nanotubes with cells within a complex cell culture model. Besides various toxicity parameters, the influence of coating with pulmonary surfactant was investigated. Pulmonary surfactant covers the entire alveolar region with the main function ...
Carter Thomas - - 2013
BACKGROUND: Use of smartphones and medical mHealth applications (apps) within the clinical environment provides a potential means for delivering elements of vascular care. This article reviews the contemporary availability of apps specifically themed to major vascular diseases and the opportunities and concerns regarding their integration into practice. METHODS: Smartphone apps ...
De Caterina Alberto R - - 2013
International guidelines recommend surgical revascularisation for unprotected left main (ULM) coronary artery disease. The introduction of drug-eluting stents (DES) as an emergency therapy has resulted in increasing numbers of patients having stents placed in ULM. As a consequence, important data on the safety and long-term outcome of PCI for ULM ...
Raut Samarth S - - 2013
The current clinical management of abdominal aortic aneurysm (AAA) disease is based to a great extent on measuring the aneurysm maximum diameter to decide when timely intervention is required. Decades of clinical evidence show that aneurysm diameter is positively associated with the risk of rupture, but other parameters may also ...
Bhat Tariq - - 2013
Transradial access for cardiac catheterization is a safe and viable approach with significantly lower incidence of major access-related complications compared with the transfemoral approach. As this form of access is getting wider acceptance among interventional cardiologists, awareness of its complications is of vital importance. Asymptomatic radial artery occlusion, non-occlusive radial ...
Shah Nirav H - - 2013
PURPOSE OF REVIEW: The incidence of spinal epidural abscess is increasing, and the understanding of the pathophysiology is evolving. Better understanding of the pathophysiology, specifically the role of ischemia, warrants a change in therapy. RECENT FINDINGS: Paralysis in spinal epidural abscess may be the result of spinal cord compression, spinal ...
Tudorache Igor - - 2013
Aims: Heart valve tissue engineering aims to create a graft with improved durability compared to routinely used valve substitutes. This study present the function and morphological changes of tissue engineered (TEV) compared to cryopreserved (CPV) aortic valve (AV) allografts in an orthotopic position in sheep. Methods and Results: Ovine AV ...
Vlodavsky Israel I Cancer and Vascular Biology Research Center, The Rappaport Faculty of Medicine and Research Institute, Technion, Haifa, Israel. - - 2013
Heparanase, the sole mammalian endoglycosidase degrading heparan sulfate, is causally involved in cancer metastasis, angiogenesis, inflammation and kidney dysfunction. Despite the wide occurrence and impact of heparan sulfate proteoglycans in vascular biology, the significance of heparanase in vessel wall disorders is underestimated. Blood vessels are highly active structures whose morphology ...
Wicky Stephan - - 2013
Thrombotic or embolic arterial occlusive disease can lead to profound ischemia and, without emergent revascularization, is associated with significant morbidity and mortality. Significant advances in the management of arterial occlusive disease range from newer thrombolytic agents to innovative catheter designs to enhance thrombolysis and thrombectomy. Most of these advances have ...
Chen Xiaofeng X Saha Cardiovascular Research Center, University of Kentucky, Lexington, KY 40536, United - - 2013
Angiotensin II (AngII) has been invoked as a principal mediator for the development and progression of both thoracic and abdominal aortic aneurysms. While there is consistency in experimental and clinical studies that overactivation of the renin angiotensin system promotes aortic aneurysm development, there are many unknowns regarding the mechanistic basis ...
Patel Niket - - 2013
Conventional drug eluting stents allow predictable long-term relief from coronary obstruction in most cases. However, rigid permanent metallic stents alter flow dynamics, abolish vascular reactivity, limit the potential for maximal vasodilation and promote ongoing inflammation and abnormalities of endothelial function. It is hypothesised that they may contribute to mal-apposition of ...
Wentzel Jolanda J - - 2013
Aims: Atherosclerotic plaques develop at low shear stress locations in the arterial tree. However, at a certain moment, plaques encroach into the lumen causing local wall shear stress (WSS) increase. Minimal information is available on the relationship between WSS and plaque composition. We investigated in human coronary arteries in vivo ...
Rosendaal Frits - - 2013
We present you with the March issue of JTH. This issue again contains a healthy mix of fundamental and clinical study papers embracing the full field of thrombosis and hemostasis. The issue is unusually strong in covering numerous clinical aspects of venous thrombosis. It contains a historical sketch of the ...
Dalyai Richard T - - 2013
Dural arteriovenous fistulas (dAVFs) are vascular lesions involving direct connections between intracranial dural arteries and venous sinuses. The goal of treatment of these vascular lesions is to alleviate symptoms and prevent future hemorrhage. While endovascular embolization remains the primary method of treatment and obliteration of dAVF recently, stereotactic radiosurgery (SRS) ...
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