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Wan Ab Naim Wan Naimah WN Department of Biomedical Engineering, Faculty of Engineering Building, University of Malaya, 50603 Kuala Lumpur, KL, - - 2014
Aortic dissection, characterized by separation of the layers of the aortic wall, poses a significant challenge for clinicians. While type A aortic dissection patients are normally managed using surgical treatment, optimal treatment strategy for type B aortic dissection remains controversial and requires further evaluation. Although aortic diameter measured by CT ...
Tanaka Michihiro M Department of Neurosurgery, Kameda Medical Center, Higashi-cho 929, Kamogawa City, Chiba, 296-8602, Japan, - - 2014
Fusiform intracranial aneurysm is one of the most difficult pathologies to treat. The role and efficacy of recent advanced endovascular technique and conventional bypass surgery are discussed.
Francis Sheila E SE Department of Cardiovascular Science, Medical School, University of Sheffield, Sheffield, United - - 2014
Atherosclerosis is a pathological process with several inputs (biological, chemical, physiological, and others) interacting slowly over a lifetime leading to coronary artery disease, significant morbidity, and a limited lifespan. Over the past two decades, biologists have used experimental preparations from cells, animals, and man to understand the biology of atherosclerosis. ...
Putu Patriawan P Department of Radiology, Sanglah Hospital, Bali, - - 2014
We discuss and illustrate various endovascular treatment options for intracranial aneurysms, to reflect common technique used in endovascular treatment of brain aneurysm. We select five cases of various aneurysm types to show assortments of endovascular treatment (EVT) are performed. Selective catheterization of the intracranial aneurysms and endovascular treatments are technically ...
Schattlo Bawarjan B Department of Neurosurgery, Kantonsspital Aarau, Switzerland; - - 2014
Aneurysmal subarachnoid haemorrhage (aSAH) occurs as a result of rupture of an intracranial aneurysm and affects a younger population compared with ischaemic stroke or intracerebral haemorrhage. Although it makes up only about 5% of all cerebrovascular events, it accounts for over a quarter of the productive life-years lost to stroke. ...
Leavesley Silas J SJ Chemical and Biomolecular Engineering, University of South Alabama, Mobile, Alabama, United States of America; Pharmacology, University of South Alabama, Mobile, Alabama, United States of America; Center for Lung Biology, University of South Alabama, Mobile, Alabama, United States of - - 2014
Coronary collateral growth (arteriogenesis) is a physiological adaptive response to transient and repetitive occlusion of major coronary arteries in which small arterioles (native collaterals) with minimal to no blood flow remodel into larger conduit arteries capable of supplying adequate perfusion to tissue distal to the site of occlusion. The ability ...
Choi Ju-Hwan JH Department of Occupational and Environmental Medicine, Dongsan Medical Center of Keimyung University, Daegu, Republic of - - 2014
The purpose of this study was to evaluate and compare changes to pulmonary function among firefighters and non-firefighters who were exposed to harmful substances in their work environments. Firefighters (n = 322) and non-firefighters (n = 107) in Daegu who received a pulmonary function test in 2008 and 2011 as well as a regular ...
Gutsche J T JT Cardiovascular and Thoracic Section, Anesthesiology and Critical Care, Perelman School of Medicine, University of Pennsylvania, Pennsylvania, - - 2014
Hypothermic circulatory arrest for adult aortic arch repair is still high-risk. Despite decades of clinical experience, significant practice variations exist around the world. These practice variations in hypothermic circulatory arrest may offer multiple opportunities to improve practice. The hypothesis of this study was that the current conduct of adult hypothermic ...
Carrion Katrina K Department of Pediatrics (Cardiology), University of California San Diego, La Jolla, California, United States of - - 2014
Aortic valve calcification is a significant and serious clinical problem for which there are no effective medical treatments. Individuals born with bicuspid aortic valves, 1-2% of the population, are at the highest risk of developing aortic valve calcification. Aortic valve calcification involves increased expression of calcification and inflammatory genes. Bicuspid ...
Ghadiri Hedeshi N N Faculty of Electrical and Computer Engineering, Tarbiat Modares University, P.O. Box 14115-143, Tehran, - - 2014
In the past decades, medical data mining has become a popular data mining subject. Researchers have proposed several tools and various methodologies for developing effective medical expert systems. Diagnosing heart diseases is one of the important topics and many researchers have tried to develop intelligent medical expert systems to help ...
Klußmann-Fricke Bastian J BJ Allgemeine & Spezielle Zoologie, Institut für Biowissenschaften, Universität Rostock, Universitätsplatz 2, 18055 Rostock, - - 2014
Though it has long been known that the prosomal ganglion of scorpions is supplied by a dense system of arteries, the pattern of this network has never been described and analyzed in detail. Using MicroCT in combination with computer aided 3D-reconstruction we provide the first detailed description of the pattern ...
Troupis Theodore G TG Department of Anatomy, Faculty of Medicine, National and Kapodistrian University of Athens, Athens, - - 2014
In this study an unusual combination of arterial, venous and neural variations discovered during dissection of cervical, axillary and brachial area of a cadaver is described. Variations are thoroughly described and literature is briefly reviewed. Lateral cord of brachial plexus was not formed; Eight Cervical root divided into anterior and ...
Shaabi Hossam I HI King Fahad Central Hospital, Jazan, Saudi Arabia Department of Surgery, Faculty of Medicine, Jazan University, Jazan, Saudi Arabia - - 2014
True aneurysms of hand arteries are rare. I present a case of a true saccular aneurysm of the distal radial artery in a 65-year-old woman with no history of trauma. The CT angiography, intraoperative features, operative procedure, histopathological examination and literature review are presented and discussed.
Bajaj Anurag A Department of Internal Medicine, Wright Center, The Commonwealth Medical College, Scranton, PA, - - 2014
Angiography use has become increasingly common worldwide. Coronary artery aneurysm may be an incidental finding during angiography. Occasionally it might be symptomatic or may become symptomatic over the course of time. Rupture of aneurysm may lead to disastrous complications. Here we present a case in which aneurysm was asymptomatic but ...
Kallidonis Panagiotis S PS Department of Urology, University of Patras, Patras, - - 2014
Drugeluting metal stents (DESs) have been extensively used in coronary and vascular disease. This type of stents has been proven to provide significantly lower restenosis rates due to the reduction of neo-intimal hyperplasia in comparison to the traditionally used bare metal stents (BMSs). The latter stents have been evaluated for ...
Colvin Kelley L KL Department of Bioengineering, University of Colorado Denver , Aurora, CO , USA ; Department of Pediatrics-Critical Care, University of Colorado Denver , Aurora, CO , USA ; Cardiovascular Pulmonary Research, University of Colorado Denver , Aurora, CO , USA ; Linda Crnic Institute for Down Syndrome, University of Colorado Denver , Aurora, CO , - - 2014
Therapeutic approaches in pediatric pulmonary arterial hypertension (PAH) are based primarily on clinician experience, in contrast to the evidence-based approach in adults with pulmonary hypertension. There is a clear and present need for non-invasive and objective biomarkers to guide the accurate diagnosis, treatment, and prognosis of this disease in children. ...
Sethi Salil S University of Texas Health Science Center, San Antonio, TX, - - 2014
Aortic stiffness is a hallmark of aging, and classic cardiovascular risk factors play a role in accelerating this process. Current changes in medicine, which focus on preventive care, have led to a growing interest in noninvasive evaluation of aortic stiffness. Aortic stiffness has emerged as a good tool for further ...
Piotin Michel M Department of Interventional Neuroradiology, Foundation Rothschild Hospital , Paris , - - 2014
Wide-neck intracranial aneurysms were originally thought to be either untreatable or very challenging to treat by endovascular means because of the risk of coil protrusion into the parent vessel. The introduction of the balloon remodeling technique (BRT) and later stents specifically designed for intracranial use has progressively allowed these lesions ...
Bekken Joost A JA Department of Vascular Surgery, Maasstad Hospital, Rotterdam, the - - 2014
The treatment of symptomatic aortoiliac occlusive disease has shifted from open to endovascular repair. Both short- and long-term outcomes after percutaneous angioplasty and stenting rival those after open repair and justify an endovascular-first approach. In this article, we review the current endovascular treatment strategies in patients with aortoiliac occlusive disease, ...
Cvetko Erika E Institute of Anatomy, Medical Faculty, Ljubljana, Slovenia; - - 2014
Anatomical variations of the carotid arterial system have a great impact on surgical approaches to the neck and radiological imaging interpretation. Although reports on internal carotid artery dolichoarteriopathy (kinking, tortuosity, coiling) have been reported, no report on dolichoarteriopathy of the external carotid artery has been described. Herein, we report a ...
Alderazi Yazan J YJ Division of Endovascular Neurosurgery, Department of Neurological Surgery, Rutgers University, New Jersey Medical School, 90 Bergen Street, Suite 8100, Newark, NJ 07101, - - 2014
Flow diverters (pipeline embolization device, Silk flow diverter, and Surpass flow diverter) have been developed to treat intracranial aneurysms. These endovascular devices are placed within the parent artery rather than the aneurysm sac. They take advantage of altering hemodynamics at the aneurysm/parent vessel interface, resulting in gradual thrombosis of the ...
Paraskevas George G Department of Anatomy, Faculty of Medicine, Aristotle University of Thessaloniki, Thessaloniki, - - 2014
The jugular venous system constitutes the primary venous drainage of the head and neck. It includes a profundus or subfascial venous system, formed by the two internal jugular veins, and a superficial or subcutaneous one, formed by the two anterior and two external jugular veins. We report one case of ...
Pearce William J WJ Center for Perinatal Biology, Loma Linda University School of Medicine, 92350, Loma Linda, CA, USA, - - 2014
For more than three decades, research programs in the Center of Perinatal Biology have focused on the vascular biology of the fetal cerebral circulation. In the 1980s, research in the Center demonstrated that cerebral autoregulation operated over a narrower pressure range, and was more vulnerable to insults, in fetuses than ...
Mehta Neil N 0000-0003-3100-842X Department of Anesthesiology, University of Colorado School of Medicine, 12405 East 17th Avenue, Aurora, CO 80045, - - 2014
Increasing evidence shows that goal-directed hemodynamic management can improve outcomes in surgical and intensive care settings. Arterial waveform analysis is one of the different techniques used for guiding goal-directed therapy. Multiple proprietary systems have developed algorithms for obtaining cardiac output from an arterial waveform, including the FloTrac, LiDCO, and PiCCO ...
Rosanio Salvatore S 0000-0003-3405-5512 Division of Cardiology, Department of Internal Medicine, University of North Texas Health Science Center, 855 Montgomery Street, PCC Room 315, Fort Worth, TX 76107, - - 2014
This systematic review aims to provide an update on pharmacological and interventional strategies for the treatment of pulmonary arterial hypertension in adults. Currently US Food and Drug Administration approved drugs including prostanoids, endothelin-receptor antagonists, phosphodiesterase type-5 inhibitors, and soluble guanylate-cyclase stimulators. These agents have transformed the prognosis for pulmonary arterial ...
Saba Raya R Saint Joseph Hospital, Department of Internal Medicine, 2900 N Lakeshore Drive, Chicago, IL 60657, - - 2014
Pulmonary arterial hypertension (PAH) has been reported as a major complication to consider and promptly manage in the use of ethanol sclerotherapy. Most of the available data on the development of PAH is derived from the use of ethanol for embolization of arteriovenous malformation, but it has been rarely reported ...
Sumalatha Suhani S Department of Anatomy, Kasturba Medical College, Manipal University, Manipal, - - 2014
The incidence of venous aneurysm is less than arterial aneurysms. Most are incidental findings with no major clinical significance. However, popliteal vein aneurysms (PVA) may be potentially life threatening, as they can be a source of pulmonary embolism and potentially even death. We report a case of right PVA in ...
Rama-Merchan Juan Carlos JC Cardiovascular Biomedical Research Unit, Royal Brompton Hospital and Harefield Trust, London, United - - 2014
Fully bioresorbable vascular scaffolds (BVS) are a new approach to the percutaneous treatment of coronary artery disease. The BVS have not yet been fully tested in complex lesions, including chronic total occlusion (CTO). We report a CTO case successfully treated with a second-generation bioabsorbable drug-eluting scaffold.
Chester Adrian H - - 2014
The aortic valve lies in a unique hemodynamic environment, one characterized by a range of stresses (shear stress, bending forces, loading forces and strain) that vary in intensity and direction throughout the cardiac cycle. Yet, despite its changing environment, the aortic valve opens and closes over 100,000 times a day ...
Kiuchi Ryuta R Department of General and Cardiothoracic Surgery, Kanazawa University, Kanazawa, Japan. Electronic address: - - 2013
It is important for coronary active perfusion systems to avoid myocardial ischemia during off-pump coronary artery bypass grafting. We have developed a new concept for a perfusion system to pump blood based on changes in helium gas volume. This system uses a conventional intra-aortic balloon pump to activate the perfusion ...
Odobescu Andrei A Department of Surgery, University of Montreal, Montreal, QC, - - 2013
To assess the utility of the Thiel arterial model in microsurgical research, we compared interrupted horizontal mattress (HM) sutures to simple interrupted (SI) sutures in human vessels. A microsurgical set-up using an operating microscope and Thiel-embalmed arteries was used to practice ten SI and HM anastomoses. Vessel patency, leak and ...
Penumatsa Krishna C KC 1Tufts Medical - - 2013
The monoamine, serotonin (5-HT), has been previously implicated in pulmonary arterial remodeling and is considered a therapeutic target for the disease pulmonary arterial hypertension. More recently, it has been recognized that the enzyme tissue transglutaminase (TG2) mediates cross linking of proteins with 5-HT, a posttranslational process of monoaminylation known as ...
Sun Zhonghua Z Zhonghua Sun, Discipline of Medical Imaging, Department of Imaging and Applied Physics, Curtin University, Perth, Western Australia 6845, - - 2013
Rapid technological developments in computed tomography (CT) imaging technique have made coronary CT angiography an attractive imaging tool in the detection of coronary artery disease. Despite visualization of excellent anatomical details of the coronary lumen changes, coronary CT angiography does not provide hemodynamic changes caused by presence of plaques. Computational ...
Vandecasteele T T Department of Morphology, Faculty of Veterinary Medicine, Ghent University, Salisburylaan 133, 9820, Merelbeke, - - 2013
The layout of the porcine atriopulmonary junction and immediately adjacent structures was investigated by gross anatomical and vascular corrosion casting studies to meet the need for more in-depth anatomical insights when using the pig as an animal model in the development of innovative approaches for surgical cardiac ablation in man. ...
Bujak Renata - - 2013
Pulmonary embolism (PE) is a common cardiovascular emergency which can lead to pulmonary hypertension (PH) and right ventricular failure as a consequence of pulmonary arterial bed occlusion. The diagnosis of PE is challenging due to non-specific clinical presentation what results in relatively high mortality. Moreover, the pathological factors associated with ...
Romo Aaron A Center for Biomedical and Healthcare Engineering, Ecole Nationale Supérieure des Mines de Saint-Etienne, CIS-EMSE, CNRS:UMR5146, LCG, 158 Cours Fauriel, 42023 Saint Etienne, France. Electronic address: - - 2013
In this study, bulge inflation tests were used to characterize the failure response of 15 layers of human ascending thoracic aortic aneurysms (ATAA). Full field displacement data were collected during each of the mechanical tests using a digital image stereo-correlation (DIS-C) system. Using the collected displacement data, the local stress ...
Tuder Rubin M RM Program in Translational Lung Research, Department of Medicine, University of Colorado School of Medicine, Aurora, Colorado. Electronic address: - - 2013
Knowledge of the pathobiology of pulmonary hypertension (PH) continues to accelerate. However, fundamental gaps remain in our understanding of the underlying pathological changes in pulmonary arteries and veins in the different forms of this syndrome. Although PH primarily affects the arteries, venous disease is increasingly recognized as an important entity. ...
Iqbal Javaid J Thorax Centre, Erasmus Medical Centre, Rotterdam, the - - 2013
Current generation of drug-eluting stents has significantly improved the outcomes of percutaneous coronary intervention by substantially reducing in-stent restenosis and stent thrombosis. However, a potential limitation of these stents is the permanent presence of a metallic foreign body within the artery, which may cause vascular inflammation, restenosis, thrombosis, and neoatherosclerosis. ...
Ricci Stefano S All the authors are affiliated with Area di Geriatria, Centro per la Salute dell'Anziano, Universita Campus Bio-Medico di Roma, Roma, - - 2013
This review aims to summarize present knowledge of foot venous return, with a special interest in clinical and research implications. It is based on the latest available publications on foot anatomy and hemodynamics. Five systems are described: the superficial veins of the sole, the deep veins of the sole (with ...
Sexton Travis T Division of Cardiovascular Medicine, The Gill Heart Institute, University of Kentucky, 255 BBRSB, 741 S. Limestone Street, Lexington, KY, 40536-0200, - - 2013
Spurred by advances in understanding the molecular basis of thrombosis, this issue of the Journal of Thrombosis and Thrombolysis is devoted to exploring aspects of novel paradigms and their potential impact on diagnosis and treatment. Complex interplay between blood and vascular cells, inflammation, and pro- and anti-coagulant pathways determines the ...
Mallios Alexandros A Department of Vascular Surgery, Institut Mutualiste Montsouris, Paris, France; Department of Surgery, University of Oklahoma, Tulsa, OK. Electronic address: - - 2013
Preservation of native arteriovenous fistulas (AVFs) in the long term can be technically challenging. Various anatomic or functional problems can occur and multiple open and/or endovascular interventions may be required for extended preservation of native accesses. In this report, we review vascular access maintenance in a 72-year-old woman during a ...
Scott Daniel J - - 2013
Sources of lower extremity and visceral arterial thromboembolism most commonly include the heart and proximal aneurysmal disease. Infrequently, further workup of "cryptogenic" emboli will reveal a mural atheroma or thrombus of the descending thoracic aorta. Without prospective data, anticoagulation and open surgical thrombectomy with or without aortic replacement have been ...
Hetts Steven W SW Department of Radiology and Biomedical Imaging; University of California; San Francisco, CA, USA - - - 2013
We describe a unique case of bilateral cervical spinal dural arteriovenous fistulas mimicking an intracranial dural arteriovenous fistula near the foramen magnum. We review its detection via MRI and digital subtraction angiography and subsequent management through surgical intervention. Pitfalls in diagnostic angiography are discussed with reference to accurate location of ...
Kutty Shelby S Division of Pediatric Cardiology, University of Nebraska College of Medicine, Children's Hospital and Medical Center, Omaha, - - 2013
Congenital mitral valve abnormalities are rare and cause mitral stenosis, regurgitation, or a combination of the two. Three-dimensional echocardiography has provided new insight into the structure and function of both normal and abnormal mitral valves. Three-dimensional imaging permits accurate anatomic diagnosis and enhances two-dimensional echocardiographic data. Moreover, it enables echocardiographers ...
Chen Michael - - 2013
Ruptured and thrombosed cerebral aneurysms pose a risk for rebleeding that may go undetected because they are angiographically occult. The presence of multiple aneurysms may further complicate efforts in accurately identifying the true source because their treatment may circumvent further necessary investigations. This case series and literature review illustrates the ...
Baragetti A A Center for the Study of Atherosclerosis, Bassini Hospital, Cinisello Balsamo, Milan, Italy; Department of Pharmacological and Biomolecular Sciences, Università degli Studi di Milano, - - 2013
Pentraxin 3 (PTX3) is an essential component of the humoral arm of innate immunity and, like C-reactive protein, is independently associated with the risk of developing vascular events. Aim of this study was to investigate, in two large population-based surveys, the Bruneck Study and the PLIC Study, whether PTX3 plasma ...
Medda E E Istituto Superiore di Sanità, National Centre for Epidemiology, Surveillance and Health Promotion, Genetic Epidemiology Unit, Viale Regina Elena 299, 00161 Rome, - - 2013
Carotid intima-media thickness (IMT) and arterial stiffness parameters, including aortic augmentation index (AIx) and pulse wave velocity (PWV), are independent predictors of stroke and cardiovascular disease. Genetic effects on these traits were never explored in a Mediterranean country. The present study aims to quantify the contribution of genes, environment and ...
Pfannmüller Bettina - - 2013
Repair of anterior mitral leaflet prolapse is one of the most challenging aspects in mitral valve repair surgery. In this review, we discuss the various techniques developed over the past three to four decades for the repair of anterior mitral leaflet prolapse, debate the pros and cons of each and ...
Bleiziffer S - - 2013
TAVI (transcatheter aortic valve implantation) is a less invasive treatment of the stenotic aortic valve while avoiding midline sternotomy and cardiopulmonary bypass. A crimped biological valve on a self-expanding or balloon-expandable stent is inserted antegradely or retrogradely under fluoroscopy, and deployed on the beating heart. Among the worldwide TAVI programs, ...
O'Connell Caroline - - 2013
Available targeted therapies for pulmonary arterial hypertension are capable only of slowing progression of the disease and a cure remains elusive. However with the improved understanding of the pulmonary vascular remodeling that characterizes the disease, there is optimism that the disconnect between preclinical and clinical studies may be bridged with ...
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