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Rouer M M Division of Vascular Surgery, Stanford University School of Medicine, Stanford, CA, - - 2014
Abdominal aortic aneurysm (AAA) is a chronic inflammatory disease affecting 4-8% of men older than 60 years. No pharmacologic strategies limit disease progression, aneurysm rupture, or aneurysm-related death. We examined the ability of rapamycin to limit the progression of established experimental AAAs. AAAs were created in 10-12-week-old male C57BL/6J mice ...
Ambalavanan Namasivayam N Division of Neonatology, Department of Pediatrics, University of Alabama at Birmingham, Birmingham, - - 2014
Pulmonary hypertension is common in bronchopulmonary dysplasia and is associated with increased mortality and morbidity. This pulmonary hypertension is due to abnormal microvascular development and pulmonary vascular remodeling resulting in reduced cross-sectional area of pulmonary vasculature. The epidemiology, etiology, clinical features, diagnosis, suggested management, and outcomes of pulmonary hypertension in ...
Martin Yvette Nicole YN Mayo - - 2014
Pulmonary arterial hypertension (PAH), a form of pulmonary hypertension (PH), is a complex disease of multifactorial origin. While new developments regarding pathophysiologic features and therapeutic options in PAH are being reported, one important fact has emerged over the years: there is a sex difference in the incidence of this disease ...
Lempel Jason K JK From the Departments of Radiology (J.K.L., A.A.F., J.J., S.J.K., R.S., H.A.N., E.K.G., C.S.W.) and Cardiac Surgery (B.G.), University of Maryland School of Medicine, Baltimore, - - 2014
Aortic dissections originating in the ascending aorta and descending aorta have been classified as type A and type B dissections, respectively. However, dissections with intimal flap extension into the aortic arch between the innominate and left subclavian arteries are not accounted for adequately in the widely used Stanford classification. This ...
Gross Bradley A BA Department of Neurosurgery, Boston Children's Hospital and Harvard Medical School, Boston, MA, 02115, USA, - - 2014
Indirect revascularization techniques for posterior circulation moyamoya are infrequently described in the literature given the relative rarity of the disease process, particularly in the best candidates for indirect approaches-children. We present a detailed, illustrated video demonstration of the occipital pial synangiosis procedure performed in a 5-year-old child. The specific advantages ...
Duan Yijie Y Department of Forensic Medicine, Huazhong University of Science and Technology, Tongji Medical College, No. 13 Hangkong Road, Hankou, Wuhan, 430030, PR China. Electronic address: - - 2014
Vaginal tightening is a kind of esthetic surgery aimed at enhancing sexual satisfaction during intercourse. Although the injective vaginal tightening procedure is informal, there are already some reports of its application. But pulmonary embolism is a really rare therapeutic complication of this procedure. We report a case of death due ...
Bersi M R MR Department of Biomedical Engineering, Yale University, New Haven, CT, - - 2014
The continuing lack of longitudinal histopathological and biomechanical data for human arteries in health and disease highlights the importance of studying the many genetic, pharmacological, and surgical models that are available in mice. As a result, there has been a significant increase in the number of reports on the biomechanics ...
Lee Chang-Young CY Department of Neurosurgery, Keimyung University School of Medicine, Daegu, Republic of - - 2014
The crossing Y-stent technique is a viable option for coiling of wide-necked bifurcation aneurysms. However, little is known about the long-term impact of this technique. Very late (>1 year) stent thrombosis following the placement of a crossing Y-stent with dual closed-cell stents for the coiling of a wide-necked basilar tip ...
Saha Kamales Kumar KK Private Practice Attached to Multiple Hospitals in Mumbai, C-801/802 Raheja Sherwood, Behind Hub Mall, Off Western Express Highway, Nirlon Compound, Goregaon East, Mumbai 400063, India. Electronic address: - - 2014
Off-pump Coronary Artery Bypass Grafting (OPCAB) is the latest innovation in cardiac surgery. However OPCAB is not adopted universally. Even there have been suggestions of abandoning OPCAB in a special report. In India, OPCAB has been successfully adopted across the board. There are various evidences which favor OPCAB and are ...
Cannon John E JE Pulmonary Vascular Disease Unit, Papworth Hospital, Papworth Everard, Cambridge, CB23 3RE, - - 2014
Pulmonary hypertension, an elevation of the mean pulmonary artery pressure ≥25 mmHg, ultimately leads to premature death due to right ventricular dysfunction. Ten treatments from three classes of drugs are licensed for the management of pulmonary arterial hypertension. These treatments have improved exercise capacity but median survival is still poor. ...
Gallino Augusto A Division of Vascular Medicine, Ospedale San Giovanni, 6500 Bellinzona, - - 2014
During the last decades, the clinical and research interest in atherosclerosis has been mostly focused on coronary arteries. After the publications of the European Society Guidelines and AHA/ACC Guidelines on Peripheral artery diseases, and of the Registry REduction in Atherothrombosis for Continued Health Registry, there has been an increased interest ...
Park Christina K CK aFaculty of Health Sciences, McMaster University bHamilton Health Sciences, Divisions of Neonatology and Hematology and Oncology, Department of Pediatrics, McMaster Children's Hospital, Hamilton, Ontario, - - 2014
Thrombotic occlusion of central venous catheters (CVCs) is a common problem in newborns. There is no guideline that systematically addresses the diagnosis, management, and prevention of this complication. The objective of this review is to establish evidence-based guidance for the management of CVC-related thrombosis. A comprehensive search of the scientific ...
Eller Jorge L JL Department of Neurosurgery, School of Medicine and Biomedical Sciences, University at Buffalo, State University of New York, Buffalo, NY, - - 2014
Flow diversion is a new endovascular technique developed for treatment of intracranial aneurysms. It is based on stent-induced modification of blood flow within and around an aneurysm inflow zone, leading to gradual intra-aneurysmal thrombosis and subsequent atrophy, while preserving flow into the parent vessel and perforating branches. Flow-diversion technique is ...
Knur Rainer R Department of Cardiology and Angiology, Allgemeines Krankenhaus Viersen, - - 2014
Carotid artery stenting has been advocated as an effective alternative to carotid endarterectomy. Periprocedural embolization of debris during endovascular treatment of carotid artery disease may result in neurological deficit. Different strategies are being developed and evaluated for their ability to minimize the clinical embolic risk. Distal filter devices, proximal and ...
Mortier Peter P FEops, Ghent, Belgium; IBiTech-bioMMeda, Ghent University, Ghent, Belgium. Electronic address: - - 2014
This study sought to better understand and optimize provisional main vessel stenting with final kissing balloon dilation (FKBD). Main vessel stenting with FKBD is widely used, but many technical variations are possible that may affect the final result. Furthermore, most contemporary stent designs have a large cell size, making the ...
Juan Yu-Hsiang YH Department of Radiology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02115, USA. ; Department of Medical Imaging and Intervention, Chang Gung Memorial Hospital, Linkou and Chang Gung University, Taoyuan 333, - - 2014
Superior vena cava (SVC) obstruction is associated with the gradual development of venous collaterals. We present a rare form of systemic-to-pulmonary subpleural collateral pathway that developed in the bridging subpleural pulmonary veins in a 54-year-old woman with complete SVC obstruction. This uncommon collateral pathway represents a rare form of acquired ...
Munhoz Alexandre Mendonça - - 2014
In microsurgical breast reconstruction, an adequate selection of recipient vessels is crucial for a successful outcome. Although the internal mammary (IM) vessels offer an attractive option, the internal mammary perforator (IMP) vessels are becoming a reliable alternative. The purpose of this study is to investigate the external diameters, lumen area, ...
Ding Dale D Department of Neurological Surgery, University of Virginia, Charlottesville, VA, United - - 2014
Treatment of giant posterior circulation aneurysms, via endovascular or microsurgical approaches, carries a high risk of morbidity and mortality. While flow-diverting stents (FDSs) represent a potent therapy for endovascular reconstruction of complex aneurysms, they are also associated with novel complications for which effective salvage techniques are lacking. We present a ...
Jackson Alexander A Centre for Population Health Sciences, University of Edinburgh, Old Medical School, Teviot Place, Edinburgh, UK, EH8 - - 2014
Abdominal aortic aneurysms (AAAs) are a vascular condition with significant risk attached, particularly if they rupture. It is, therefore, critical to identify and repair these as an elective procedure before they rupture and require emergency surgery. Repair has traditionally been an open surgical technique that required a large incision across ...
Silva Marques João J 1 Department of Cardiology I, Santa Maria Hospital - CHLN, Lisbon Academic Medical Centre, CCUL, Lisbon, - - 2014
Lower limb ischaemia is the most frequent complication of cardiac catheterisation in children. It is often overlooked, but it can cause significant disability and may limit arterial access sites to repeat diagnostic or interventional catheterisations. A narrative review of the literature on arterial access site thrombosis in children was carried ...
Fonseca Diogo A DA aLaboratory of Pharmacology, Faculty of Pharmacy, University of Coimbra bCenter of Cardiothoracic Surgery, Coimbra University Hospitals, Coimbra, - - 2014
Coronary artery disease is recognized as a major health problem worldwide, particularly because of the associated morbidity and mortality. Coronary artery bypass grafting has been an established mainstay in the treatment of this disease for almost half a century and is arguably the most intensively studied surgical procedure ever undertaken. ...
Min Seung-Kee SK 0000-0001-6849-3786 Department of Surgery, Seoul National University College of Medicine, Seoul, - - 2014
Arterial restenosis frequently develops after open or endovascular surgery due to intimal hyperplasia. Since tissue transglutaminase (TG2) is known to involve in fibrosis, wound healing, and extracellular matrix remodeling, we examined the role of TG2 in the process of intimal hyperplasia using TG2-null mice. The neointimal formation was compared between ...
Tian Wen W VA Palo Alto Health Care System, Stanford University, Med111P, 3801 Miranda Ave., Palo Alto, CA, 94304, - - 2014
Leukotrienes (LTs) are lipid mediators derived from the 5-lipoxygenase (5-LO) pathway of arachidonic acid metabolism and are markers and mediators of pulmonary inflammation. Research over the past two decades has established that LTs modulate inflammation in pulmonary arterial hypertension (PAH). The purpose of this review was to summarize the current ...
Loewe Christian C *Section of Cardiovascular and Interventional Radiology, Department of Biomedical Imaging and Inmage-guided Therapy, Medical University of Vienna †Department of Radiology, General Hospital Hietzing with Neurological Department Rosenhügel, Vienna, - - 2014
The need for functional estimation of the relevance of stenosis to guide appropriate treatment in coronary artery disease has recently been shown. Invasive coronary angiography (CA) with invasive measurement of the pressure gradient in patients with coronary stenoses becomes the method of choice for treatment decision-making in invasive cardiology. Coronary ...
Lie K H KH The Taylor Laboratory, Department of Anatomy and Neuroscience, University of - - 2014
Previous studies of venous anatomy lack the detail of their arterial counterparts due to (i) the technical challenge of retrograde perfusion against competent valves and (ii) anterograde venous perfusion that fails to capture significant portions of the area of interest. A novel technique, retrograde hydrogen peroxide (H2O2) priming, dilates veins ...
Lee Moon Il MI Department of Surgery, Inha University School of Medicine, Incheon, - - 2014
Endotension is an unpredictable late complication of endovascular aortic aneurysm repair (EVAR). This case report will discuss the successful treatment of enlarged aneurysmal sac due to endotension using the relining technique. An 81-year-old male complained of nondecreasing huge aneurysm sac. He had undergone EVAR for infrarenal abdominal aortic aneurysm 7 ...
Andersen L K LK Department of Dermato-Venereology, Aarhus University Hospital, Aarhus C, - - 2014
Cutaneous polyarteritis nodosa (CPN) is a rare vasculitis affecting the small-and medium-sized arteries in the reticular dermis and subcutaneous tissue. CPN should be distinguished from systemic polyarteritis nodosa (PAN), which is an aggressive systemic vasculitis with internal organ involvement. Extracutaneous findings of CPN include fever, myalgia, arthralgia, and neuropathy.(1) In ...
Mai Jeffrey C - - 2014
As neuroendovascular interventions for both ruptured and unruptured intracranial aneurysms have come to the forefront, careful follow-up and strategies for retreatment of aneurysmal recurrences have become increasingly important. Endovascular approaches have also proven to be valuable adjuncts for managing recurrent aneurysms previously treated by open microsurgical approaches. Fortunately, retreatment of ...
Vance Awais - - 2014
There has been an exponential growth in the endovascular treatment of intracranial aneurysms over the past three decades and it is now the primary mode of treatment in the cerebrovascular community. Despite the proven safety and efficacy of bare platinum coils, criticism of the durability of endovascular coiling with respect ...
Freeman Melanie M St. Paul's Hospital, University of British Columbia, Vancouver, - - 2014
Stroke has emerged as one of the most concerning complications following transcatheter aortic valve replacement (TAVR); associated with high morbidity and mortality. We discuss the potential mechanisms of stroke following TAVR, as well as the newly developed embolic protection devices aimed to reduce the risk of stroke. © 2014 Wiley ...
Chavan Rajendra R Department of Radiology, Jehangir Hospital, Pune, Maharashtra, - - 2014
Endovascular treatment of wide necked and large/giant intracranial aneurysms is challenging. The goal of this study was to evaluate the Liberty stent system in the rabbit elastase aneurysm model for 30, 90, and 180 days. The Altes elastase model was used to create aneurysms in the right common carotid artery ...
Grandhi Ramesh R Department of Neurological Surgery, University of Pittsburgh Medical Center, Pittsburgh, - - 2014
External ventricular drain (EVD) placement is often a routine but lifesaving neurosurgical procedure performed throughout the world. Misadventures involving the procedure are well documented throughout the literature. However, we present a unique case of middle meningeal artery pseudoaneurysm formation after EVD placement not before described and provide a review of ...
Pushparajah Kuberan K Department of Congenital Heart Disease, Evelina London Children's Hospital, London, United - - 2014
Stenting the atrial septum to achieve decompression of the atrium is well described and commonly performed via a percutaneous catheter approach under combined fluoroscopic and echocardiographic guidance. We describe two successful cases of a hybrid approach to atrial stenting under echocardiographic guidance alone, as a viable alternative approach.
Xiong Jiang J Department of Vascular Surgery, Vascular Center of Military, Chinese PLA General Hospital, Beijing, - - 2014
Thoracic endovascular aortic repair (TEVAR) of arch pathology presents special challenges for revascularization. To obtain an anatomic reconstruction of the arch arteries, in situ fenestration with extra-anatomic bypass has been increasingly used in TEVAR. We report a case involving TEVAR for a pseudoaneurysm at zone 2 of the thoracic aorta ...
Parissis Haralabos H Cardiothoracic Department, Royal Victoria Hospital, Belfast, - - 2014
Bilateral internal mammary arteries directed to the left coronaries are gaining popularity; an increasing level of evidence nowadays supports this surgical strategy. On the other hand, composite right internal mammary artery, radial artery, and gastroepiploic artery targeting high-grade stenotic lesions in the right coronary artery system may confer improved mid- ...
Wang Zhiyun Z Department of Orthopedics, Liuhua Qiao Hospital, Guangzhou, Guangdong, - - 2014
Objective The aim of this study was to demonstrate the anatomical structures of the transoral approach to the craniovertebral junction. We evaluated the necessary exposure field and the safety of this approach. Methods Surgical operations with the transoral approach were performed on 36 cadaver specimens. The special anatomical structures were measured surrounding ...
Martufi G G Department of Civil Engineering and Centre for Bioengineering Research and Education, Schulich School of Engineering, University of Calgary, 2500 University Dr NW, Calgary, T2N1N4, - - 2014
An aortic aneurysm is a permanent and localized dilatation of the aorta resulting from an irreversible loss of structural integrity of the aortic wall. The infrarenal segment of the abdominal aorta is the most common site of aneurysms; however, they are also common in the ascending and descending thoracic aorta. ...
Singer Joel J Department of Developmental Disability Neuropsychiatry, School of Psychiatry, University of New South Wales, Sydney, Australia; Centre of Healthy Brain Ageing (CHeBA), School of Psychiatry, University of New South Wales, Sydney, - - 2014
Arterial Stiffness is a known predictor of cardiovascular disease, and has also been associated with markers of cerebral small vessel disease as well as poor cognitive function and cognitive decline. The consistency of these associations and their relationship to each other are unclear. We conducted a systematic review of the ...
Le Victoria P VP Department of Biomedical Engineering, Saint Louis University, St. Louis, MO, - - 2014
Mice with a smooth muscle cell (SMC)-specific deletion of Fibulin-4 (SMKO) show decreased expression of SMC contractile genes, decreased circumferential compliance, and develop aneurysms in the ascending aorta. Neonatal administration of drugs that inhibit the angiotensin II pathway encourages the expression of contractile genes and prevents aneurysm development, but does ...
Attenhofer Jost Christine H - - 2014
Thoracic aortic aneurysms can be triggered by genetic disorders such as Marfan syndrome (MFS) and related aortic diseases as well as by inflammatory disorders such as giant cell arteritis or atherosclerosis. In all these conditions, cardiovascular risk factors, such as systemic arterial hypertension, may contribute to faster rate of aneurysm ...
Favelier S S Département de radiologie diagnostique et interventionnelle, unité digestif, thoracique et oncologique, CHU Dijon, 14, rue Paul-Gaffarel, BP 77908, 21079 Dijon cedex, France. Electronic address: - - 2014
The availability of intra-arterial hepatic therapies (radio and/or chemo-embolisation, intra-arterial hepatic chemotherapy) has convinced radiologists to perfect their knowledge of the anatomy of the liver arteries. These sometimes, complex procedures most often require selective arterial catheterization. Knowledge of the different arteries in the liver and the peripheral organs is therefore ...
Kasemi Holta H Vascular Surgery Unit, Department of Surgery, "San Francesco" Hospital, Nuoro, Italy. Electronic address: - - 2014
An 81-year-old man presented with rapid enlargement of a 2-year known abdominal aortic and common iliac aneurysms. A hybrid approach to preserve both hypogastric arteries (HAs) was planned: a bifurcated endograft for the right aortoiliac axis, right femoral-to-left femoral artery bypass and left external-to-internal iliac artery stent graft placement. Urethral ...
Nitschke Yvonne - - 2014
In recent years, mechanisms of arterial calcifications are beginning to be elucidated. Arterial calcification is now considered as an actively regulated process resembling osteogenesis within the arterial wall orchestrated by a number of systemic or constitutively expressed mediators. Genetic studies of rare monogenic human disorders and studies of naturally occurring ...
Golledge Jonathan J The Vascular Biology Unit, Queensland Research Centre for Peripheral Vascular Disease, School of Medicine and Dentistry, James Cook University Townsville, Queensland, Australia 4811. - - 2014
Traditionally abdominal aortic calcification (AAC) has received less intensive study than coronary artery calcification. The widespread use of abdominal imaging has however encouraged recent investigation of this problem. Human association studies suggest that older age, chronic kidney disease and osteoporosis are the most important risk factors for AAC. AAC severity ...
Konoplyannikov Mikhail - - 2014
Arterial calcification (AC) is a hallmark of many serious diseases, including atherosclerosis, chronic kidney disease, and diabetes. AC may also develop as a side-effect of therapy with anticoagulants, such as warfarin which is widely used for prophylaxis of thrombosis. In our studies, we established the relation between warfarin-induced AC and ...
Sanghvi Kintur K Deborah Heart & Lung Institute, 200 Trenton Road, Browns Mills, New - - 2014
We report a case of percutaneous closure of a congenital perimembranous ventricular septal defect (VSD) performed via a radial artery and basilic vein accesses. We further discuss the technique, advantages, and limitation of this innovative approach for perimembranous VSD closure.
Lodh Suhrid S Department of Radiology, Royal North Shore Hospital, St Leonards, - - 2014
This article will review the rationale for hepatic arterial administration of agents to treat melanoma liver metastases, the techniques and practical considerations pertinent to hepatic arterial therapy, the variety of agents that have been used and the reported outcomes. Recent and emerging developments will be highlighted and the potential role ...
Zanaty Mario - - 2014
The management of unruptured aneurysms (UAs), whose incidence is increasing, is still a controversial issue. Many studies have been investigating the link between the geometry of the aneurysm and the risk of future rupture in order to bring forth a clear decision plan. The different estimators studied are the aneurysm's ...
Eller Jorge L - - 2014
Endovascular techniques are well suited for the treatment of posterior circulation aneurysms. This review describes the endovascular management of these aneurysms and discusses relevant technical advances.
Ahmed Saman - - 2014
Associated pulmonary arterial hypertension related to connective tissue disorders carries significant morbidity and a high mortality. The purpose of this review article is to present an updated account of the pathogenesis, epidemiology, clinical signs and symptoms, diagnostic modalities, treatment regimens, and prognosis of this disorder.
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