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Choudhri O O Neurosurgery, Stanford University, Palo Alto, CA, - - 2014
Placement of external ventricular drains is a common, life-saving neurosurgical procedure indicated across a variety of settings. While advances have made the procedure quite safe, the potential for iatrogenic morbidity and mortality continues. Herein, we document our experience with the endovascular management of three pseudoaneurysms associated with EVD placement. We ...
Tanweer O O New York University, New York, NY, - - 2014
Cerebral aneurysms (CAs) and abdominal aortic aneurysms (AAAs) are both degenerative vascular pathologies that manifest as an abnormal dilation of the arterial wall. They arise with different morphologies in different types of blood vessels under different haemodynamic conditions. Although these aneurysms are treated as very different and separate pathologies, we ...
Bhagavatula Sastry K S SK Department of Cardiology, CARE Hospital, Hyderabad, Andhra Pradesh, - - 2014
There is scant published data about pulmonary hypertension (PH) from the developing countries. True prevalence of the disease, its biology, etiology and response to treatment are not well known, and they are likely to be somewhat different from that of the developed countries. In this review, we will discuss the ...
Pasha Qadar Q Department of Genetics, CSIR-Institute of Genomics and Integrative Biology, New Delhi, - - 2014
Pulmonary hypertension (PH) is a phenotype characterized by functional and structural changes in the pulmonary vasculature, leading to increased vascular resistance.[12] The World Health Organization has classified PH into five different types: arterial, venous, hypoxic, thromboembolic or miscellaneous; details are available in the main guidelines. Group I of this classification, ...
Boueiz Adel A Division of Pulmonary and Critical Care Medicine, Johns Hopkins University, Baltimore, MD, - - 2014
The explosive growth of medical literature on pulmonary hypertension (PH) has led to a steady increase in awareness of this disease within the medical community during the past decade. The recent revision of the classification of PH is presented in in the main guidelines. Group 1 PH or pulmonary arterial ...
Mayer Eckhard E Department of Thoracic Surgery, Kerckhoff Clinic, Bad Nauheim, - - 2014
Chronic thromboembolic pulmonary hypertension (CTEPH) is categorized as group IV in the WHO classification for pulmonary hypertension. The disease requires a very low index of suspicion for identification and needs a special diagnostic approach utilizing clinical, radiological, and hemodynamic tools. As CTEPH is potentially curable, all efforts should be consumed ...
Minai Omar A OA Associate Professor of Medicine, Respiratory Institute, Cleveland Clinic, Ohio, - - 2014
The biomarker is an indicaror of a biological or pathological process. Clinical observations, measures or environmental events, or measured laboratory values can all be biomarkers in the appropriate setting. An ideal biomarker reflects the underlying biological process, predicts clinical events, is easily obtainable, is reproducible and is not prohibitively expensive. ...
Sen Shurjo K SK National Human Genome Research Institute, NIH, Bethesda, MD 20892, - - 2014
Coronary artery calcification (CAC) is a heritable and definitive morphologic marker of atherosclerosis that strongly predicts risk for future cardiovascular events. To search for genes involved in CAC, we used an integrative transcriptomic, genomic, and protein expression strategy by using next-generation DNA sequencing in the discovery phase with follow-up studies ...
Spacek M M Dpt. of Cardiology, University Hospital Motol, - - 2014
Since its introduction in 1982, transcranial Doppler ultrasound (TCD) has become an important diagnostic and monitoring tool and its usefulness has been well established in many clinical applications. In carotid artery stenting (CAS), TCD has mostly been reserved for the optimization of emboli protection devices. Currently, with increasing use of ...
Rojas-Marte Geurys G Department of Medicine, Maimonides Medical Center, Brooklyn, NY, USA - - 2014
A 63-year-old female was diagnosed with severe aortic stenosis, who underwent a diagnostic coronary angiography via transradial approach prior an aortic-valve replacement. After imaging the left coronary system, entrapment of the diagnostic catheter was encountered as a result of spasm of the radial artery. An arteriogram of the arm revealed ...
Rabinovitch Marlene M From the Cardiovascular Institute and Department of Pediatrics (M.R.) and Department of Medicine (M.R.N.), Stanford University School of Medicine, CA; INSERM UMR_S 999, LabEx LERMIT, Centre Chirurgical Marie Lannelongue, Le Plessis-Robinson and Université Paris-Sud, School of Medicine, Le Kremlin-Bicêtre (C.G., M.H.); and AP-HP, Service de Pneumologie, Centre de Référence de l'Hypertension Pulmonaire Sévère, DHU Thorax Innovation, Hôpital de Bicêtre, France (M.H.). - - 2014
This review summarizes an expanding body of knowledge indicating that failure to resolve inflammation and altered immune processes underlie the development of pulmonary arterial hypertension. The chemokines and cytokines implicated in pulmonary arterial hypertension that could form a biomarker platform are discussed. Pre-clinical studies that provide the basis for dysregulated ...
Paulin Roxane R From the Department of Medicine, University of Alberta, Edmonton, Alberta, - - 2014
Numerous molecular abnormalities have been described in pulmonary arterial hypertension (PAH), complicating the translation of candidate therapies to patients because, typically, 1 treatment addresses only 1 abnormality. The realization that in addition to pulmonary artery vascular cells, other tissues and cells are involved in the syndrome of PAH (eg, immune ...
Perez Vinicio de Jesus VD Division of Pulmonary and Critical Care Medicine, Stanford University Medical Center, 300 Pasteur Drive Grant S140B, Stanford, CA 94305, USA. Electronic address: - - 2014
Pulmonary arterial hypertension (PAH) is a life-threatening disorder that is associated with elevated pulmonary pressures and right heart failure resulting from progressive loss and thickening of small pulmonary arteries. Despite their ability to improve symptoms, current therapies fail to prevent disease progression, leaving lung transplantation as the only therapy in ...
Martin David M DM Department of Mechanical Engineering, Dublin Institute of Technology, Bolton Street, Dublin 1, - - 2014
In many computational fluid dynamics (CFD) studies of stented vessel haemodynamics, the geometry of the stented vessel is described using non-deformed (NDF) geometrical models. These NDF models neglect complex physical features, such as stent and vessel deformation, which may have a major impact on the haemodynamic environment in stented coronary ...
Georgakarakos Efstratios E Department of Vascular Surgery, University Hospital of Alexandroupolis, "Democritus" University of Thrace, Alexandroupolis, Greece, - - 2014
Endovascular aneurysm repair (EVAR) is considered to be the treatment of choice for abdominal aortic aneurysms (AAA). Despite the initial technical success, EVAR is amenable to early and late complications, among which the migration of the endograft (EG) with subsequent proximal endoleak (Type Ia) leads to repressurization of the AAA ...
Taichman Darren B - - 2014
Choices of pharmacological therapies for pulmonary arterial hypertension (PAH) are ideally guided by high-level evidence. Provide clinicians advice regarding pharmacologic therapy for adult patients with PAH as informed by available evidence. This guideline was based on systematic reviews of English language evidence published between 1990 and November 2013, identified using ...
Sagar Jayesh - - 2014
Aneurysms infra-patellar region are uncommon. Of them, true aneurysms are very rare and that of posterior tibial artery are extremely rare. The more common, pseudoaneurysms are commonly associated with trauma whereas the true ones are linked with either inflammatory or mycotic origins.Case Presentation: We reported another case of true aneurysm ...
Kamtchum Tatuene J J From the Neurology Division (J.K.T., P.P., A.K.), Department of Clinical Neurosciences; Hyperbaric Medicine Centre (R.P.), Department of Emergency Medicine; and Neuroradiology Division (K.O.L., M.I.V.), Department of Imaging and Medical Information Sciences, Geneva University Hospitals, Geneva, - - 2014
Diving-related decompression illness is classified into 2 main categories: arterial gas embolism and decompression sickness. The latter is further divided into types 1 and 2, depending on the clinical presentation. MR imaging is currently the most accurate neuroimaging technique available for the detection of brain and spinal cord lesions in ...
Yagel Simcha S Division of Obstetrics and Gynecology, Hadassah-Hebrew University Medical Centers, Jerusalem, - - 2014
Scanning of the fetal venous system is a necessary part of complete fetal organ scanning to confirm landmark anatomy such as the ductus venosus, course of the umbilical veins, etc, and whenever cardiovascular anomalies are identified, to exclude associated anomalous development of the fetal veins. We aimed to develop a ...
Bertanha Matheus M Department of Surgery and Orthopedics, Botucatu Medical School, São Paulo State University (UNESP), Botucatu, SP, Brazil; Blood Transfusion Center, Cell Engineering Lab., Botucatu Medical School, São Paulo State University (UNESP), Botucatu, SP, Brazil. Electronic address: - - 2014
Clinical experience for peripheral arterial disease treatment shows poor results when synthetic grafts are used to approach infrapopliteal arterial segments. However, tissue engeneering may be an option to yield surrogate biocompatible neovessels. Thus, biological decellularized scaffolds could provide natural tissue architecture to use in tissue engineering, when the absence of ...
Liu Qin Q Department of Mechanical Engineering, University of Texas at San Antonio, San Antonio, TX 78249, - - 2014
Artery bent buckling has been suggested as a possible mechanism that leads to artery tortuosity, which is associated with aging, hypertension, atherosclerosis, and other pathological conditions. It is necessary to understand the relationship between microscopic wall structural changes and macroscopic artery buckling behavior. To this end, the objectives of this ...
Qi Xing-Shun XS Xing-Shun Qi, Ming Bai, Zhi-Ping Yang, Dai-Ming Fan, Xijing Hospital of Digestive Diseases, Fourth Military Medical University, Xi'an 710032, Shaanxi Province, - - 2014
Nowadays, transjugular intrahepatic portosystemic shunt (TIPS) has become a mainstay treatment option for the management of portal hypertension-related complications in liver cirrhosis. Accumulated evidence has shown that its indications are being gradually expanded. Notwithstanding, less attention has been paid for the selection of an appropriate stent during a TIPS procedure. ...
Tauil Karla Mette Waldrich KM Laboratory of Respiratory Physiology, Universidade de Brasília, Brasília - DF, Brazil. Electronic address: - - 2014
Pulmonary arterial hypertension (PAH) is associated to cellular and structural alterations of lung vasculature. Endothelial dysfunction promotes vasoconstriction, smooth muscle hypertrophy, intimal proliferation, angioproliferative plexiform lesions, and in situ thrombosis increasing pulmonary vascular resistance and arterial stiffness. Indeed, an inflammatory component has been defined in PAH on the last years. ...
Rayner J J Department of Cardiology, Oxford University Hospitals NHS Trust, Oxford, - - 2014
Aortic valve disease is common and has significant impact on prognosis and quality of life. In this educational review, we cover the pathophysiology, presentation and assessment of aortic stenosis (AS) and aortic regurgitation (AR), including the role of imaging modalities beyond echocardiography. We review current treatment strategies and emphasise the ...
Segreto Antonio A Department of Science and Medical-Surgical Biotechnologies, Cardiac Surgery Unit, Università degli Studi di Roma "Sapienza", Latina, - - 2014
This review discusses the role of biomarkers for both diagnoses and disease monitoring before, during, and after treatment of aortic dissection.
Yahagi K K CVPath Institute, Inc., Gaithersburg, MD, USA - - - 2014
Peripheral artery disease (PAD) is an emerging problem especially with aging population and increase in the incidence of diabetes and metabolic syndrome. The disease is histologically characterized by the presence of moderate to severe calcification and fibrous plaques as compared to coronary and carotid atherosclerotic disease, which are richer in ...
Singh G D GD University of California Davis Medical Center, Division of Cardiovascular Medicine and the Vascular Center Sacramento, CA, USA - - - 2014
Nitinol self-expanding stents are increasingly used to treat symptomatic peripheral arterial disease. Despite reduction in procedural complications and rates of stent fracture, femoropopliteal in-stent restenosis (FP-ISR) remains a common and important clinical problem. Due to heterogenous patient and angiographic characteristics, treatment of FP-ISR continues to evolve. Multiple modalities have been ...
Jayasuriya S S Dana 3 Cardiology, FACC Yale University New Haven, CT, USA - - - 2014
The prevalence of PAD is expected to increase as the population ages and the treatment for chronic disease becomes more sophisticated. The safety, efficacy, and lower cost of endovascular treatment for peripheral vascular disease of the lower extremities when compared with surgical revascularization are well known. Despite the clinical improvements ...
Van den Berg J C JC Service of Interventional Radiology Ospedale Regionale di Lugano, Lugano, Switzerland - - - 2014
This paper will describe the technique of the treatment of in-stent restenosis of the infrainguinal arteries, using a combined technique of laser debulking followed by drug-eluting balloon angioplasty. The results of this technique from the literature will be discussed, and a comparison with other techniques that are currently used will ...
Donzelli R R Department of Neurosurgical Sciences "Federico II" University of Naples, Naples, Italy - - - 2014
This study describes five experimental techniques for the surgical treatment of giant aneurysms based on the resection of the aneurysm sac and reconstruction of the arterial wall. The aneurysm was realized with a venous graft implanted with end-to-side anastomosis on the common carotid artery on 50 rabbits (with each technique ...
Winokur Ronald S RS Division of Interventional Radiology, Department of Radiology, Weill Cornell Vascular, New York-Presbyterian Hospital/Weill Cornell Medical College, New York, - - 2014
Superficial venous insufficiency is a common cause of lower-extremity symptoms of pain and swelling. A thorough understanding of the superficial venous anatomy, as well as gaining knowledge of treatment approaches, can direct one's approach to providing an appropriate treatment for desired and durable outcomes. This article reviews the details of ...
Wyatt Kristine K Kristine Wyatt practices at the Eye Institute in Tulsa, Okla. The author has disclosed no potential conflicts of interest, financial or - - 2014
Vision changes and ophthalmic complaints may represent potentially serious, sometimes fatal, systemic illnesses. This article summarizes the presenting signs and symptoms of retinal artery occlusion, giant cell arteritis, and oculomotor nerve palsy.
Luciani Giovanni Battista GB Division of Cardiac Surgery, University of Verona, Verona, Italy. Electronic address: - - 2014
The association between truncus arteriosus and total anomalous pulmonary venous return is exceedingly rare. Here described is a neonate presenting with a common arterial trunk and a previously unreported "scimitar-like" mixed total pulmonary venous return who underwent a successful one-stage repair. The unprecedented anatomic pattern of the systemic and pulmonary ...
Kaneko Tsuyoshi T Division of Cardiac Surgery, Department of Surgery, Brigham and Women's Hospital-Harvard Medical School, Boston, - - 2014
With the recent emergence of transcatheter valve replacement, high-risk cases of structural valve deterioration after mitral bioprosthesis can be treated with valve-in-valve transcatheter mitral valve replacement (TMVR). The transapical approach has become the principal access for TMVR, but we report an alternative direct access for TMVR-transjugular transseptal route-in an 81-year-old woman with ...
Numasawa Yohei Y Department of Cardiology, Ashikaga Red Cross Hospital, 284-1 Yobe-cho, Ashikaga, Tochigi, Japan. - - 2014
We report on a 74-year-old man with chronic total occlusion (CTO) of the right coronary artery treated with percutaneous coronary intervention using the bidirectional kissing-balloon technique. When an antegrade approach fails, a retrograde approach to recanalize a CTO is reasonable. However, when the exit of the CTO is bifurcated and ...
Zhao Xiaohui X Cardiovascular Disease Research Center, Xinqiao Hospital, Third Military Medical University, Chongqing, China. zxhwn@tmmu.edu.cn or - - 2014
Kissing-balloon inflation has been developed for percutaneous bifurcation interventions to improve outcomes and reduced angiographic (re)stenosis. However, this procedure is sometimes technically challenging due to inability to deliver the side-branch (SB) balloon across the structure of the main vessel stent(s). The balloon anchoring technique is reported to enable equipment delivery ...
Mommerot Arnaud A Research Center, Montreal Heart Institute and Université de Montréal, Montreal, Quebec, Canada; Department of Cardiovascular Surgery, Montreal Heart Institute and Université de Montréal, Montreal, Quebec, Canada; Department of Cardiac Surgery, University Hospital of Strasbourg, Strasbourg, - - 2014
Whereas it is established that endothelin-1 elicits sustained deleterious effects on the cardiovascular system during cardiopulmonary bypass (CPB), presently it remains unknown whether the inhaled administration of the dual ETA and ETB antagonist tezosentan prevents the development of pulmonary endothelial dysfunction. A prospective, randomized laboratory investigation. University research laboratory. Landrace ...
Yeong Kim Se S Department of Occupational and Environmental Medicine and Institute of Environmental and Occupational Medicine, Busan Paik Hospital, Inje University, Busan/Busanjin-Gu, Republic of - - 2014
Fractional exhaled nitric oxide (FeNO) has been implicated as a pulmonary biomarker in various respiratory disease, including COPD. Measurement of FeNO is a simple, non-invasive tool for assessing airway inflammation. Neverthless, the usefulness of FeNO measurements in COPD patient in clinical practice is unclear. The objective of this review was ...
Russell Bronwyn C BC Medical Student, Division of Maternal Fetal Medicine, Department of Obstetrics and Gynecology, Wake Forest University School of Medicine, Winston-Salem, - - 2014
Although the diagnostic workup and management regimens for many of the common fetal thoracic lesions have been well described, the understanding of pulmonary agenesis is more limited. A better understanding of the published reports of this condition is essential to provide proper care for these complicated pregnancies. The aims of ...
Tse Donald M L DM Department of Radiology, Oxford University Hospitals, John Radcliffe Hospital, Oxford, OX3 9DU, - - 2014
Surveillance after endovascular abdominal aortic aneurysm repair (EVAR) is widely considered mandatory. The purpose of surveillance is to detect asymptomatic complications, so that early secondary intervention can prevent late aneurysm rupture. CT angiography has been taken as the reference standard imaging test, but there is increasing interest in using other ...
Neamtu I - - 2014
Coronary artery stents used for the treatment of patients with coronary artery disease develop the practice of interventional cardiology after they were first introduced in the mid-1980s. Since then, with dozens of companies involved in the development of new and innovative anti-restenotic drugs, polymeric coatings and stent platforms has made ...
Tuder Rubin M RM Program in Translational Lung Research, Division of Pulmonary Sciences and Critical Care Medicine, Department of Medicine, University of Colorado School of Medicine, 12700 East 18th Avenue, Research Complex 2, Room 9001, Aurora, CO 80045, USA. Electronic address: - - 2014
The current understanding of the pathology that underlies pulmonary vascular and right ventricular remodeling in pulmonary hypertension is discussed. Although recent studies underscored the importance of intima and media remodeling and, for the first time, the relevance of perivascular inflammation, much is needed to move the field forward. Reassessment of ...
Chan Simon K C SK Department of Anaesthesia and Intensive Care, The Chinese University of Hong Kong, Shatin, NT, Hong Kong SAR, - - 2014
To describe the use of cerebral oximetry to detect a lack of right cerebral perfusion resulting from a malpositioned catheter used for antegrade cerebral perfusion during deep hypothermic circulatory arrest (DHCA). The simple corrective surgical adjustment that followed averted a potentially serious complication. A 57-yr-old male with a type-A aortic ...
Werner M M Vascular Clinic, HanuschKrankenhaus,Vienna, Austria - - - 2014
The implantation of metallic stents has become a standard procedure to improve the outcome after angioplasty of the superficial femoral artery (SFA). However, the permanent presence of a metallic stent in the femoropopliteal artery is associated with a number of potential disadvantages. Thus, the use of a bioresorbable scaffold, which ...
Mattison Julie A JA Translational Gerontology Branch, Intramural Research Program, National Institute on Aging, NIH, Suite 100, 251 Bayview Boulevard, Baltimore, MD 21224, - - 2014
Central arterial wall stiffening, driven by a chronic inflammatory milieu, accompanies arterial diseases, the leading cause of cardiovascular (CV) morbidity and mortality in Western society. An increase in central arterial wall stiffening, measured as an increase in aortic pulse wave velocity (PWV), is a major risk factor for clinical CV disease ...
Rossi Michele - - 2014
Renal artery aneurysm is a rare disorder with a high mortality rate in the event of rupture, the most frequent complication, which can also occur in lesions smaller than those indicated for treatment by current criteria. Surgery is still the first-line treatment, although a growing trend toward endovascular management of ...
Abla Adib A AA Department of Neurological Surgery, University of California, San - - 2014
Proximal anterior inferior cerebellar artery (AICA) aneurysms are generally managed endovascularly. However, surgery is a viable option when endovascular treatment is unfavorable. AICA aneurysms that are small, unruptured, at the artery's origin, and laterally directed are ideal for the Kawase approach, providing a more direct view than a retrosigmoid exposure. ...
Hendrix Philipp P Division of Neurosurgery, Department of Surgery, University of Alabama at Birmingham, Birmingham, - - 2014
The arterial supply to the upper cranial nerves is derived from a complex network of branches derived from the anterior and posterior cerebral circulations. We performed a comprehensive literature review of the arterial supply of the upper cranial nerves with an emphasis on clinical considerations. Arteries coursing in close proximity ...
Zhao Yan E YE Department of Medical Imaging, Jinling Hospital, Clinical School of South Medical University, Nanjing, Jiangsu, - - 2014
The recent introduction of multidetector computed tomography scanners has significantly improved computed tomography angiographic (CTA) applications, especially for the evaluation of medium- and small-arterial structures. CTA of the superior mesenteric artery has been reported previously. However, there have been few systematic and detailed reviews of the superior mesenteric artery pathologies ...
Mathieu Patrick P Department of Surgery, Laboratoire d'Études Moléculaires des Valvulopathies (LEMV), Groupe de Recherche en Valvulopathies (GRV), Quebec Heart and Lung Institute/Research Center, Laval University, Quebec, - - 2014
Calcific aortic valve disease (CAVD) is a chronic process leading to fibrosis and mineralization of the aortic valve. Investigations in the last several years have emphasized that key underlying molecular processes are involved in the pathogenesis of CAVD. In this regard, the processing of lipids and their retention has been ...
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