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Results 601 - 650 of 1931
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Muthialu Nagarajan N Department of Cardiothoracic Surgery, Great Ormond Street Hospital for Children NHS Trust, London, - - 2013
Combined tracheobronchial and thoracic vascular injury in children following blunt trauma to the chest is potentially life-threatening and almost certain to be fatal unless managed promptly. We report one such incident where prompt identification and early aggressive surgical management prevented an almost certain fatal outcome in a 5-year-old girl with ...
Green Kelly D KD Vanderbilt Heart and Vascular Institute, Nashville, TN 37232-8802, - - 2013
Hybrid coronary revascularization combines the benefits of both percutaneous coronary intervention (PCI) and coronary artery bypass grafting (CABG) in the treatment of multivessel coronary artery disease (CAD) by combining the benefits of the LIMA-to-LAD graft and drug eluting stent (DES) to non-LAD regions. Through this approach, a patient receives the ...
Austin Eric D ED Department of Pediatrics, Division of Allergy, Immunology, and Pulmonary Medicine, Vanderbilt University School of Medicine, Nashville, Tennessee, - - 2013
Most subtypes of pulmonary arterial hypertension (PAH) are characterized by a greater susceptibility to disease among females, although females with PAH appear to live longer after diagnosis. While this "estrogen paradoxȍ of enhanced female survival despite increased female susceptibility remains a mystery, recent progress has begun to shed light upon ...
Cristofaro Brunella B CIRB Collège de France, Inserm U1050/CNRS UMR 7241, Paris, - - 2013
Arteriogenesis requires growth of pre-existing arteriolar collateral networks and determines clinical outcome in arterial occlusive diseases. Factors responsible for the development of arteriolar collateral networks are poorly understood. The Notch ligand Delta-like 4 (Dll4) promotes arterial differentiation and restricts vessel branching. We hypothesized that Dll4 may act as a genetic ...
Rothuizen Tonia C - - 2013
Haemodialysis vascular access patency is severely compromised by fistula non-maturation and access stenosis. Intimal hyperplasia (IH) is considered the culprit lesion in failed fistulas, resulting in luminal narrowing and stenosis. This review focuses on the biology and pathophysiology of fistula failure and highlights not only the classically associated IH but ...
Takahashi Hiroaki - - 2013
Although median sternotomy is the accepted approach to the heart for cardiac surgery, minimally invasive approaches including partial sternotomies have recently been developed. However, such strategies might lead to sternal overriding, instability, and fracture or division of the internal thoracic arteries. Furthermore, a full sternotomy would be required to address ...
Sinzinger Helmut - - 2013
Ventilation/perfusion scintigraphy is the diagnostic tool of choice for detection and monitoring of pulmonary embolism. However, the knowledge on its value for other or concurrent pathologies is poor. In this review scintigraphic characteristics of the main pathologies, interpretation and artefacts are described. Together with the understanding of pathophysiology of the ...
Schleh Carsten - - 2013
The article of Gasser et al. [Part Fibre Toxicol. 24; 9:17, 2012] describes the interaction of carbon nanotubes with cells within a complex cell culture model. Besides various toxicity parameters, the influence of coating with pulmonary surfactant was investigated. Pulmonary surfactant covers the entire alveolar region with the main function ...
Carter Thomas - - 2013
BACKGROUND: Use of smartphones and medical mHealth applications (apps) within the clinical environment provides a potential means for delivering elements of vascular care. This article reviews the contemporary availability of apps specifically themed to major vascular diseases and the opportunities and concerns regarding their integration into practice. METHODS: Smartphone apps ...
De Caterina Alberto R - - 2013
International guidelines recommend surgical revascularisation for unprotected left main (ULM) coronary artery disease. The introduction of drug-eluting stents (DES) as an emergency therapy has resulted in increasing numbers of patients having stents placed in ULM. As a consequence, important data on the safety and long-term outcome of PCI for ULM ...
Raut Samarth S SS Department of Mechanical Engineering, Carnegie Mellon University, Pittsburgh, PA, - - 2013
The current clinical management of abdominal aortic aneurysm (AAA) disease is based to a great extent on measuring the aneurysm maximum diameter to decide when timely intervention is required. Decades of clinical evidence show that aneurysm diameter is positively associated with the risk of rupture, but other parameters may also ...
Bhat Tariq - - 2013
Transradial access for cardiac catheterization is a safe and viable approach with significantly lower incidence of major access-related complications compared with the transfemoral approach. As this form of access is getting wider acceptance among interventional cardiologists, awareness of its complications is of vital importance. Asymptomatic radial artery occlusion, non-occlusive radial ...
Shah Nirav H - - 2013
PURPOSE OF REVIEW: The incidence of spinal epidural abscess is increasing, and the understanding of the pathophysiology is evolving. Better understanding of the pathophysiology, specifically the role of ischemia, warrants a change in therapy. RECENT FINDINGS: Paralysis in spinal epidural abscess may be the result of spinal cord compression, spinal ...
Vlodavsky Israel I Cancer and Vascular Biology Research Center, The Rappaport Faculty of Medicine and Research Institute, Technion, Haifa, Israel. - - 2013
Heparanase, the sole mammalian endoglycosidase degrading heparan sulfate, is causally involved in cancer metastasis, angiogenesis, inflammation and kidney dysfunction. Despite the wide occurrence and impact of heparan sulfate proteoglycans in vascular biology, the significance of heparanase in vessel wall disorders is underestimated. Blood vessels are highly active structures whose morphology ...
Wicky Stephan - - 2013
Thrombotic or embolic arterial occlusive disease can lead to profound ischemia and, without emergent revascularization, is associated with significant morbidity and mortality. Significant advances in the management of arterial occlusive disease range from newer thrombolytic agents to innovative catheter designs to enhance thrombolysis and thrombectomy. Most of these advances have ...
Chen Xiaofeng X Saha Cardiovascular Research Center, University of Kentucky, Lexington, KY 40536, United - - 2013
Angiotensin II (AngII) has been invoked as a principal mediator for the development and progression of both thoracic and abdominal aortic aneurysms. While there is consistency in experimental and clinical studies that overactivation of the renin angiotensin system promotes aortic aneurysm development, there are many unknowns regarding the mechanistic basis ...
Patel Niket - - 2013
Conventional drug eluting stents allow predictable long-term relief from coronary obstruction in most cases. However, rigid permanent metallic stents alter flow dynamics, abolish vascular reactivity, limit the potential for maximal vasodilation and promote ongoing inflammation and abnormalities of endothelial function. It is hypothesised that they may contribute to mal-apposition of ...
Wentzel Jolanda J - - 2013
Aims: Atherosclerotic plaques develop at low shear stress locations in the arterial tree. However, at a certain moment, plaques encroach into the lumen causing local wall shear stress (WSS) increase. Minimal information is available on the relationship between WSS and plaque composition. We investigated in human coronary arteries in vivo ...
Rosendaal Frits - - 2013
We present you with the March issue of JTH. This issue again contains a healthy mix of fundamental and clinical study papers embracing the full field of thrombosis and hemostasis. The issue is unusually strong in covering numerous clinical aspects of venous thrombosis. It contains a historical sketch of the ...
Dalyai Richard T - - 2013
Dural arteriovenous fistulas (dAVFs) are vascular lesions involving direct connections between intracranial dural arteries and venous sinuses. The goal of treatment of these vascular lesions is to alleviate symptoms and prevent future hemorrhage. While endovascular embolization remains the primary method of treatment and obliteration of dAVF recently, stereotactic radiosurgery (SRS) ...
Vieira Miguel Silva - - 2013
Coronary artery stent thrombosis is an uncommon but potentially catastrophic complication. The risk of very late stent thrombosis (VLST) raises important safety issues regarding the first generation of drug-eluting stents (DES). Although several complex mechanisms for VLST have been suggested and various predictors have been described, its pathophysiology is not ...
Hayman Mw - - 2013
Interventional neuroradiology is a rapidly expanding field, and the complexity and duration of these procedures makes anaesthetic support essential to their success. Such has been the development in this area, that the American Heart Association has published a scientific statement on the indications for these procedures. A detailed understanding of ...
Negi Smita I - - 2013
Frequency domain optical coherence tomography (FD-OCT) is a new intravascular imaging modality utilizing near-infrared light to generate high-quality images. It provides a unique and detailed view of the vessel wall and vessel lumen. FD-OCT has been increasingly used in coronary interventions; however, there is limited experience regarding the use of ...
Hagl Christian - - 2013
Aneurysmal diseases are often silent but can cause potentially life-threatening complications in cases of dissection or rupture. Surgical strategies depend on the involved part of the aorta and frequently require extracorporeal circulation and circulatory arrest. From data available from the Centers for Disease Control and Prevention, aneurysm disease is the ...
Nikolć Igor - - 2013
Natural course of aneurysms that occur on blood vessels of the brain singles out the need for understanding the mechanism of the occurrence of aneurysm wall rupture and identification of anatomic characteristics as predictive factors for hemorrhage to occur. In this study we comparatively present results of our researches and ...
Gottlieb Danielle - - 2013
The pulmonary trunk (PT) structure and function are abnormal in multiple congenital cardiovascular diseases. Existing surgical treatments of congenital malformations of the right ventricular outflow tract and PT do not provide a long-term replacement that can adapt to normal growth. Although there is strong interest in developing tissue-engineered approaches for ...
Sella David M - - 2013
With the introduction of retrievable inferior vena cava filters, the number being placed for protection from pulmonary embolism is steadily increasing. Despite this increased usage, the true incidence of complications associated with inferior vena cava filters is unknown. This article reviews the known complications associated with these filters and suggests ...
Hsieh Victar - - 2013
Cardiac catheterization and coronary intervention via the radial approach is increasingly adopted as the preferred vascular access to avoid transfemoral vascular complications. Recent clinical trials have confirmed that radial access reduces vascular complications and local bleeding with similar procedural efficacy. Transradial access has inherent technical challenges, including smaller vessel size ...
Bostan Mehmet M Department of Cardiology, Medical School, Recep Tayyip Erdoğan University Rize - - 2013
Percutaneous coronary intervention is an important modality in the treatment of coronary artery disease. These procedures are usually completed successfully, but occasionally serious complications are encountered. In this paper, we present the case of an undeflatable stent balloon, which is an extremely rare complication that has not been described in ...
Brown Hilary A HA Department of Vascular Surgery, Yale University School of Medicine, New Haven, - - 2013
We present a case of a 70-year-old male with a past medical history of coronary artery bypass grafting and end stage renal disease who presented with massive hemoptysis. He had a history of methicillin-resistant Staphylococcus aureus endocarditis, with infection and removal of endocardial pacing leads. His work-up revealed a 2.9-cm ...
Darabian Sirous S St. John Cardiovascular Research Center, Harbor-UCLA Los Angeles Biomedical Research Institute, 1124 W Carson Street, Torrance, CA 90502, USA. - - 2013
Carotid ultrasonography is a safe and available noninvasive diagnostic tool that provides information about the carotid arteries' characteristics and may be used for early detection of coronary artery disease as well as cardiovascular and stroke event risk stratifications. We performed a systematic search of articles discussing carotid ultrasonography in the ...
Wimalasena Yashvi - - 2013
High altitude pulmonary edema is a life-threatening condition that remains a concern for climbers and clinicians alike. Within the last decade, studies have shown ultrasonography to be valuable in the accurate diagnosis of a variety of lung pathologies, including cardiogenic pulmonary edema, pleural effusion, pneumothorax, and lung consolidation. Recently, studies ...
Suzuki Yuichiro J - - 2013
Substantial experimental evidence suggests the usefulness of antioxidants for the treatment of various forms of pulmonary hypertension. However, no recommendations have yet been made if patients with pulmonary hypertension should receive pharmacologic and/or dietary antioxidants. Our understanding of antioxidants has evolved greatly over the last two decades, from the primitive ...
Sherif Hisham M F - - 2013
The majority of cases of atrial fibrillation (AF) are the result of triggers originating in the area of the pulmonary veins. The reason for the predilection for that area remains unclear. We sought to examine the different mechanisms responsible for this observation through an extensive search of the medical literature, ...
Sato Tatsuo - - 2013
PURPOSE: This photographic review of actual dissections was compiled to demonstrate the various lymphatic pathways and their relationships to the surrounding structures to facilitate the development of QOL surgical procedures. METHODS: For the purpose of demonstration, three male adult specimens, prepared with 10 % formaldehyde solution injected through the femoral artery ...
Rodríguez-Flores Marcela - - 2013
BACKGROUND: There is uneven association between obesity, traditional risk factors, and cardiovascular events. We aimed to analyze the relation between cardiovascular risk factors, including obesity, with the severity of atherosclerosis in different arterial territories. METHODS: Arteries from five territories (circle of Willis, carotids, coronaries, aorta, and renal) were taken from ...
Srinivas Budanur Chikkaswamy - - 2013
Budd-Chiari syndrome is a rare disease characterized by obstruction of outflow in the hepatic vein and/or the inferior vena cava (IVC). Percutaneous transluminal angioplasty and stent placement is nowadays considered to be the first-line treatment for central venous disease because of its minimal-invasive approach. IVC reconstruction by surgical approach is ...
Sheppard Dean D Lung Biology Center, Department of Medicine, UCSF, San Francisco, California 94143-2922, USA. - - 2013
Clinical vignette: A 76-year-old man consults you for increasing shortness of breath over the past two years and an increasing requirement for home oxygen. A video-assisted thoracoscopic lung biopsy shows findings of usual interstitial pneumonitis, and he has no identifiable cause for pulmonary fibrosis, so he is considered to have ...
Duggal Bhanu - - 2013
Pulmonary vein (PV) stenosis is a known complication of PV isolation(PVI) procedures for atrial fibrillation (AF). Treatment can be percutaneous or surgical. We describe in this report a case of recurring PV stenosis after both surgical and percutaneous procedures, highlighting a number of novel interventional techniques. We also provide a ...
De Caterina Alberto Ranieri - - 2013
We describe a case of a left main coronary artery (LMCA) chronic total occlusion (CTO), which we elected to treat through percutaneous coronary intervention (PCI). In this case report, we briefly review the prevalence of LMCA CTO, discuss the feasibility of PCI versus surgical revascularization and highlight the importance of ...
Loukas Marios - - 2013
There are a manifold number of variations and anomalies of the origin and course of coronary arteries described in the literature. The incidence of such variations in the general population is reported to range between 0.3 and 1.6 %. Although uncommon, they may be benign or produce symptoms ranging from mild ...
Gory Benjamin - - 2013
BACKGROUND AND IMPORTANCE:: The goal of spinal dural arteriovenous fistula (DAVF) treatment is to permanently occlude the proximal draining vein and the fistula itself, which can be achieved by open surgery or by endovascular treatment. The endovascular approach is currently the primary treatment, but it requires the presence of an ...
Weng Lihui - - 2013
Natural polymer-derived materials have gained increasing interest in the biomedical field. Polysaccharide has obvious advantages over other polymers employed for biomedical applications due its exceptional biocompatibility and biodegradability. None of the spherical embolic agents in clinic is biodegradable. In the current study, microspheres prepared from chitosan and carboxymethyl cellulose (CMC) ...
Thomas Matthew - - 2013
As we uncover the complex pathophysiology underlying idiopathic and familial pulmonary arterial hypertension, multiple disease associated pathways, cell types and processes reveal links to elements of the serotonin system. Beyond the original 'serotonin hypothesis' observed with anorexigens, and the latterly demonstrated association with vascular tone and pulmonary artery smooth muscle ...
Baloglu Orkun - - 2013
The treatment of pulmonary arterial hypertension (PAH) associated with chronic lung disease of infancy (CLDI) is becoming commonplace. However, an optimal approach to the monitoring of this treatment has not been clearly established, and data suggest that such therapy may not be without risk. This study assessed the feasibility and ...
Phisitkul Phinit - - 2013
Background:For triple arthrodesis, a single medial incision has been proposed to avoid lateral wound complications and has demonstrated satisfactory fusion rates. This study aimed to compare the disruption to the arterial supply of the talus between the single-medial-incision approach and the 2-incision approach.Methods:The 2 approaches for triple arthrodesis were compared ...
Shiraishi Shuichi S Division of Thoracic and Cardiovascular Surgery, Niigata University Graduate School of Medical and Dental Sciences, Niigata, Japan. - - 2013
Tracheobronchial obstruction and unilateral hypoplasia of the pulmonary artery are serious barriers to successful Fontan completion. We describe a 5-year old girl with left bronchial obstruction, hypoplasia of the left pulmonary artery and a single ventricle (double inlet left ventricle). She had undergone external stenting to treat left bronchial stenosis ...
Goh Debbie - - 2013
Cardiovascular disease is one of the major causes of death in the world. Coronary stenting in percutaneous coronary intervention (PCI) has revolutionized the field of cardiology. Coronary stenting is seen as a less invasive procedure compared to coronary artery bypass graft (CABG) surgery. Two main types of stents currently exist ...
Querques Giuseppe - - 2013
Retinal vascular occlusive disorders constitute one of the major causes of blindness and impaired vision. There is marked controversy on their pathogeneses, clinical features and particularly their management. Recently, advances in clinical research added antivascular endothelial growth factor, corticosteroids and sustained-release implants to our armamentarium in the management of retinal ...
Osbun Joshua W - - 2013
OBJECTIVE: Sphenoid wing region dural arteriovenous fistulas (DAVFs) are rare lesions that are typically fed by middle meningeal artery (MMA) feeders and that drain via the sphenoparietal sinus or middle cerebral vein. We describe a unique case of a medial sphenoid wing fistula draining exclusively via the basal vein of ...
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