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Jickling Glen C GC From the Department of Neurology and the MIND Institute (G.C.J.), University of California at Davis, Sacramento; and the Department of Neurology and Stroke Program (S.C.), Wayne State University, Detroit, - - 2014
Despite recent advances in medical and surgical treatments to prevent arterial stroke, the cerebrovascular burden of atherosclerosis remains high. Factors associated with a high risk for arterial stroke include stenosis >50% and ulcerated plaque. Given the important role of inflammation in atherosclerotic plaque progression and rupture, a measure of plaque ...
Karmonik C C Department of Neurosurgery, Houston Methodist, Houston, Texas, - - 2014
To quantitatively compare hemodynamics simulated with steady-state and transient computational fluid dynamics (CFD) simulations in cerebral aneurysms with single inflow, with focus at the aneurysm ostium. Transient and steady-state CFD simulations were performed in 10 cerebral aneurysms. Distributions and average values for pressure, helicity, vorticity, and velocity were qualitatively compared ...
Cebral J R JR From the Center for Computational Fluid Dynamics (J.R.C., F.M., M.R.), College of Sciences, George Mason University, Fairfax, Virginia; and Departments of Radiology (S.H., Y.-H.D., B.J.E., R.K., D.F.K.) and Neurosurgery (D.F.K.), Mayo Clinic, Rochester, - - 2014
Predicting the outcome of flow diversion treatment of cerebral aneurysms remains challenging. Our aim was to investigate the relationship between hemodynamic conditions created immediately after flow diversion and subsequent occlusion of experimental aneurysms in rabbits. The hemodynamic environment before and after flow-diversion treatment of elastase-induced aneurysms in 20 rabbits was ...
Labib Mohamed A MA 1Division of Neurosurgery, Department of Surgery, University of Ottawa, Ottawa, ON, Canada 2Department of Neurosurgery, The Ohio State University, Columbus, Ohio, USA 3Department of Otolaryngology -Head and Neck Surgery, The Ohio State University, Columbus, Ohio, USA 4Department of Otolaryngology, University of Ottawa, Ottawa, ON, Canada 5Aurora Neuroscience Innovation Institute, Aurora St. Luke's Medical Center, Milwaukee, WI, - - 2014
Injuring the internal carotid artery (ICA) is a feared complication of endoscopic endonasal approaches. To introduce a comprehensive ICA classification scheme pertinent to safe endoscopic endonasal cranial base surgery. Anatomical dissections were performed in thirty-three cadaveric specimens (bilateral). Anatomical correlations were analyzed. Based on anatomical correlations, the ICA may be ...
Brunel H H Service de neuroradiologie, hôpital de La Timone, CHU de Marseille, 264, rue Saint-Pierre, 13385 Marseille cedex 5, France. Electronic address: - - 2014
Carotid cavernous sinus fistulas are a potentially severe pathology. Their basic standard treatment is an occlusion of the CCF performed by retrograde venous catheterization via the inferior petrous sinus. When the inferior petrous sinuses are occluded, other alternative venous routes are possible with various subsequent difficulties and risks. We report ...
Rubinshtein Ronen R Cardiology Department, Lady Davis Carmel Medical Center, Haifa, - - 2014
Aims: Accurate positioning of aorto-ostial coronary stents is challenging. Coronary CT angiography (CCTA) allows detailed imaging of the coronary sinuses and implanted stents. We utilised CCTA to evaluate the accuracy of aorto-ostial stenting and to assess the efficacy of conventional angiography for guiding these procedures. Methods and results: We analysed ...
Ankri Rinat - - 2014
In this study we report the use of gold nanorods (GNRs) as absorption contrast agents in the diffusion reflection (DR) method for the in vivo detection of atherosclerotic injury. The early detection and characterization of atherosclerotic vascular disease (ASVD) is considered to be one of the greatest medical challenges today. ...
Choi Jin-Ho JH 1Cardiovascular Imaging Center, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, - - 2014
-Coronary collateral flow is alternative source of myocardial perfusion in patients with totally occluded coronary arteries. Clinical evaluation of collateral flow has been limited by the need of invasive measurements. We investigated whether non-invasive coronary computed tomography (CT) angiography can evaluate the angiographic extent of coronary collateral flow. -We enrolled ...
Sugawara Jun J aHuman Technology Research Institute, National Institute of Advanced Industrial Science and Technology, Ibaraki, Japan bCardiovascular Aging Research Laboratory, Department of Kinesiology and Health Education, The University of Texas at Austin, Austin, Texas, USA cDepartment of Health and Physical Education, Kokugakuin University, Tokyo, - - 2014
Brachial-ankle pulse wave velocity (baPWV) is one of few indices of arterial stiffness that has been incorporated into a routine clinical setting. baPWV is associated with markers of central arterial stiffness, but the absolute values are substantially higher than other PWV measures. We tested the hypothesis that the height-based formulas ...
Wright James M JM Department of Neurological Surgery, The Neurological - - 2014
Since the first surgery for an intracranial aneurysm in 1931, neurological surgeons have long strived to determine the optimal methods of surgical correction. Significant challenges of aneurysm clipping include intraoperative rupture and complex dome morphology. Hypothermia, cardiopulmonary bypass, pharmacologically induced hypotension, and cardiac standstill are a few of the methodologies ...
Anzai Hitomi - - 2014
Background: A modern technique for the treatment of cerebral aneurysms involves insertion of a flow diverter stent. Flow stagnation, produced by the fine mesh structure of the diverter, is thought to promote blood clotting in an aneurysm. However, apart from its effect on flow reduction, the insertion of the metal ...
Leone Antonio Maria AM Department of Cardiovascular Sciences, Catholic University of the Sacred Heart, Rome, - - 2014
Aims: Despite the fact that fractional flow reserve (FFR) is better than angiography in guiding PCI, in the real world the choice to perform PCI is generally based on angiography. Three-dimensional quantitative coronary angiography (3D-QCA) may increase the accuracy of angiography, especially in intermediate coronary artery stenosis (ICAS). The aim ...
Prasad Rahul M - - 2014
Cell-based perfusion studies have provided great insight into fluid-sensing mechanisms, such as primary cilia in the renal and vascular systems. However, the intrinsic limitations of in vitro cell culture, such as the inability to reflect cellular organization within tissues, has distanced observed paradigms from possible clinical developments. Here we describe ...
Hanratty Colm - - 2014
In contemporary practice there are three main methods that can be employed when attempting to open a chronic total occlusion (CTO) of a coronary artery; antegrade wire escalation, antegrade dissection re-entry and retrograde dissection re-entry. This editorial will attempt to clarify the anatomical features that can be identified to help ...
Tuan-Mu Ho-Yi HY Department of Biomedical Engineering, National Cheng Kung University, #1 University Rd., Tainan, 701, - - 2014
Most tissues, including those to be decellularized for tissue engineering applications, are frozen for long term preservation. Such conventional cryopreservation has been shown to alter the structure and mechanical properties of tissues. Little is known, however, how freezing affects decellularization of tissues. The purpose of this study was two-fold: to ...
Abouei Mehrizi A A Biomechanics Lab, Life Science Engineering Department, Faculty of New Sciences and Technologies, University of Tehran , Amir Abad, North Kargar Street, Tehran , Iran - - 2014
Abstract Palpation is one of the applied methods that surgeons usually use during surgery in order to verify the health condition of a tissue/organ. In fact, most of surgical assessments are based on analysis of the force feedback received from tissue/organ via palpation. Although palpation has a key role in ...
Stenzel Fabian F Department of Radiology, Charité - Universitätsmedizin Berlin, Campus Charité Mitte, Charitéplatz 1, 10117, Berlin, - - 2014
Comparison of bolus tracking with a fixed threshold versus a manual fast start for coronary CT angiography. We retrospectively analysed 320-row coronary CT angiography of 50 patients with suspected or known coronary artery disease. Twenty-five examinations were initiated by a bolus tracking method (group 1), 25 examinations with a manual ...
Kuan May Y S MY a School of Mechanical Engineering, University of Birmingham , Birmingham B15 2TT , - - 2014
A transient fluid-structure interaction (FSI) model of a congenitally bicuspid aortic valve has been developed which allows simultaneous calculation of fluid flow and structural deformation. The valve is modelled during the systolic phase (the stage when blood pressure is elevated within the heart to pump blood to the body). The ...
García G G Systems Engineering and Automatic Control Department - EUP, University of the Basque Country (UPV/EHU), Escuela Universitaria Politécnica, Plaza Europa 1, 20018 San Sebastián, Spain. Electronic address: - - 2014
An abdominal aortic aneurysm (AAA) is a localized abnormal enlargement of the abdominal aorta with fatal consequences if not treated on time. The endovascular aneurysm repair (EVAR) is a minimal invasive therapy that reduces recovery times and improves survival rates in AAA cases. Nevertheless, post-operation difficulties can appear influencing the ...
Requejo Flavio F Department of Interventional Radiology, Hospital Nacional de Pediatría "Prof. J.P. Garrahan" , Buenos Aires , - - 2014
ABSTRACT Purpose: To describe a technique for micro catheterization of the external ophthalmic artery (EO) in pigs for investigational and training purposes. Methods: Carotid angiography was performed in seven male domestic pigs. The external ophthalmic artery was reached with a microcatheter in order to administer a neoplastic drug in the ...
Gasiunas V V 1Clinique de l'Alma, Paris, - - 2014
The palmar triangle is an area vascularized by perforator arteries arising from the common digital palmar arteries. The aim of this article was to perform an anatomical study of common digital palmar arteries perforators. Twelve injected specimens were included in this study. The purpose was to quantify the number of ...
Egenrieder Stephanie S Abteilung für Kardiologie, Robert-Bosch-Krankenhaus, Auerbachstr. 110, 70376, Stuttgart, Germany, - - 2014
With older age and increasing comorbidities, conventional operative procedures for severe symptomatic aortic stenosis are associated with a high surgical risk. To date, transfemoral transcatheter aortic valve implantation (TF-TAVI) represents an accepted alternative method of intervention with a cardiovascular and all-cause mortality similar to operative replacement at early and long-term ...
Speiser U - - 2014
Abstract Objectives: For evaluation of aortic valve area (AVA) transthoracic echocardiography (TTE) is the method of choice. Cardiac magnetic resonance (CMR) at 1.5 Tesla is an alternative. If quantification of whole range of AVA with no to severe aortic stenosis is also possible and reliable in higher magnetic field strength ...
Akiba Tadashi T Department of Surgery, The Jikei University Kashiwa Hospital, Kashiwa, Chiba, - - 2014
The fissureless lobectomy or anterior fissureless technique is a novel surgical technique, which avoids dissection of the lung parenchyma over the pulmonary artery during lobectomy by open thoracotomy approach or direct vision thoracoscopic surgery. This technique is indicated for fused lobes. We present two cases where thoracoscopic pulmonary segmentectomy was ...
Masmoudi Hicham H Department of Thoracic Surgery, Tenon Hospital, Paris, - - 2014
Mediastinoscopy remains the gold standard for surgical exploration of the mediastinum. The use of this approach to access the left thoracic cavity could be complicated by vascular or neurological lesion. The aim of this experimental work was to describe a new approach to the left thoracic cavity through a cervical ...
Tanriover Necmettin N Department of Neurosurgery, Cerrahpa┼ča Medical Faculty, Istanbul - - 2014
Object The object of this study was to delineate the microsurgical anatomy of the cisternal segment of the anterior choroidal artery (AChA). The authors also propose a new classification of this segment on the basis of its complicated course within the carotid and crural cisterns in relation to important neurovascular ...
Wang Liang L Department of Otolaryngology-Head and Neck Surgery, Wexner Medical Center, The Ohio State University, Columbus, OH, USA; Department of Otolaryngology-Head and Neck Surgery, 1st Affiliated Hospital, Zhengzhou University, Zhengzhou, Henan, - - 2014
Introduction: Endonasal approaches to the pterygopalatine fossa for epistaxis, or as part of a transpterygoid approach have been popularized in part due to our ability to control the terminal branches of the maxillary artery (MA). Surgical landmarks are useful to identify these arteries. Therefore, identification of surface features on the ...
Tsiopoulos Vasileios V Dipartimento di Scienze Cardiovascolari, Unità di Chirurgia del Cuore e dello Scompenso Cardiaco, Università Cattolica del Sacro Cuore, Policlinico Agostino Gemelli, Roma, - - 2014
We describe a variation of the standard intraoperative transit time flow evaluation that allows the assessment of the anastomotic patency of in situ arterial grafts before the release of the aortic cross clamp. The advantages of this technique are the immediate correction of technical imperfections and the evaluation of native ...
Kim Tae Eun TE Department of Radiology, Dongguk University Ilsan Hospital, Dongguk University, 814 Siksa-dong, Ilsandong-gu, Goyang-si, Gyeonggi-do, 410-773, South - - 2014
Pulmonary sequestration is rarely presented as massive hemoptysis and is conventionally treated by a surgical procedure. Here, we report a case of a 25-year-old man who presented with massive hemoptysis that rapidly developed into a hypovolemic shock. Multidetector computed tomographic angiography showed active contrast extravasation from the aberrant systemic artery ...
Wong Dennis Tl DT Monash Cardiovascular Research Centre, Department of Medicine (Monash Medical Centre)Monash University and Monash Heart, Monash Health, 246 Clayton Road, Clayton, 3168 VIC, Australia; Discipline of Medicine, University of Adelaide, Adelaide, Australia. Electronic address: - - 2014
To compare the diagnostic accuracy of combined CTP + CTA, TAG320 + CTA and CTP + TAG320 + CTA (MDCT-IP) assessment in predicting significant fractional-flow-reserve (FFR). Computed-tomography-coronary-angiography (CTA) has limited specificity for predicting functionally significant stenoses. Novel CT techniques including adenosine-stress-computed-tomography-myocardial-perfusion (CTP) and transluminal-attenuation-gradient (TAG320) may improve the diagnostic accuracy ...
Mildner Toralf T Max Planck Institute for Human Cognitive and Brain Sciences, Leipzig, - - 2014
The arterial transit time (δa ) is a potentially important physiological parameter which may provide valuable information for the characterization of cerebrovascular diseases. The present study shows that δa can be measured by arterial spin labeling (ASL) applied quasi-continuously in an amplitude-modulated fashion at the human neck. Imaging was performed ...
Croteau Etienne E Department of Nuclear Medicine and Radiobiology, Sherbrooke Molecular Imaging Center, Étienne-Le Bel Clinical Research Center of CHUS, Université de Sherbrooke, Québec, - - 2014
The purpose of this study was to develop a minimally invasive procedure to derive an arterial input function (AIF) in rats through tail artery blood sampling for pharmacokinetic modeling in preclinical PET molecular imaging studies. The procedure involved a microvolumetric blood counter (μBC) and a correction to compensate for delay ...
Kan Jing J Department of Cardiology, Nanjing First Hospital, Nanjing Medical University, Nanjing, Jiangsu 210006, - - 2014
Angiographic evaluation of left main coronary artery (LMCA) bifurcation lesions is often limited. two dimensional (2D) quantitative coronary angiography (QCA) with segmental analysis provides accuracy for quantification of the degree of stenosis in the main vessel and side branch ostium but can be affected by foreshortening and variable magnification. The ...
Dangoisse Vincent V C H U Mont Godinne UCL , Yvoir , - - 2014
Abstract Delivery of coronary stents can be challenging, but the use of a second or 'buddy' wire helps the progression of equipment through tortuous and rigid vessels. We successfully positioned a coronary stent in a distal lesion, intentionally jailing the buddy wire during stent delivery. The jailed wire was then ...
Tremblay Catherine C Université Laval, Dept. of Mechanical Engineering, Quebec, Quebec, Canada ; - - 2014
Tissue engineering appears as a promising option to create new heart valve substitutes able to overcome the serious drawbacks encountered with mechanical substitutes or tissue valves. The objective of this paper is to present the construction method of a new entirely biological stentless aortic valve using the self-assembly method and ...
Wei-Wei Wu W Department of Vascular Surgery, PUMC Hospital, CAMS and PUMC, Beijing 100032, - - 2014
Objective To construct an experimental abdominal aortic aneurysm(AAA)swine model with Dacron patch for evaluating endovascular aneurysm repair(EVAR)technique.Methods The experimental pigs were generally anesthetized for the open procedure of an aneurysm model creation with Dacron and subsequent arteriography and EVAR with stent graft.Repeat arteriography was performed after 3-month follow-up.Results AAA models ...
Vilchez-Monge A L AL Hospital General Universitario Gregorio Marañón, Madrid (Spain):2 Department of Statistics. Instituto de Investigación Sanitaria Gregorio, Marañón - - - 2014
Background: Liver transplantation (LT) implies hemodynamic instability, making invasive monitoring of cardiac output (CO) mandatory. Intermittent thermodilution with pulmonary artery catheter (PAC) remains the clinical gold standard to measure CO. The agreement between PAC and new monitoring methods in LT needs to be further investigated. Our aim is to clarify ...
Chubb H H Department of Congenital Cardiology, Evelina London Children's Hospital, London, UK; King's College London, London, UK; Work performed at Evelina London Children's Hospital, - - 2014
Objectives: The pulmonary valve (PV) annulus is routinely measured angiographically in PV stenosis prior to balloon dilation. We sought to establish whether this radiation exposure is justified, or whether echocardiographic measurements prior to the procedure are sufficient to guide balloon selection. Background: Previous studies have found a strong correlation between ...
Chang Sung Soo SS Department of General Thoracic, Breast, and Endocrinological Surgery, Faculty of Medicine, Kagawa University, 1750-1 Ikenobe, Miki-cho, Kita-gun, Kagawa, 761-0793, - - 2014
The prognosis of patients with emphysema is poor as there is no truly effective treatment. Our previous study showed that the alveolar space was smaller and the microvessel density was higher in a canine emphysema model after the intrapulmonary arterial administration of gelatin microspheres slowly releasing basic fibroblast growth factor ...
Sander C Hällsjö CH Department of Anaesthesiology, Surgical Services and Intensive Care Medicine, Karolinska University Hospital, Solna SE-171 76, - - 2014
/st>It is important to be able to accurately monitor cardiac output (CO) during high-risk surgery and in critically ill patients. The invasiveness of the pulmonary artery catheter (PAC) limits its use, and therefore, new minimally invasive methods for CO monitoring are needed. A potential method is estimation of CO from ...
Murasato Yoshinobu Y Department of Cardiovascular Medicine, Heart Center, New Yukuhashi Hospital, Yukuhashi, - - 2014
Aims: To define the optimal kissing balloon inflation (KBI) after single-stent deployment in a coronary bifurcation model. Methods and results: We deployed stents in main vessels (MV) followed by KBI in various conditions and compared the stent configurations. A) KBI at the operator's discretion vs. under the guidelines of minimal ...
Descalzo M M Unidad de Imagen, Clínica Creu Blanca, Barcelona, España; Unidad de Imagen Cardiaca, Servicio de Cardiología, Hospital de la Santa Creu i Sant Pau, Barcelona, España. Electronic address: - - 2014
To confirm the value of the coronary artery calcium (CAC) score as an indicator of significant coronary artery disease (CAD) in the asymptomatic Spanish population, using noninvasive coronary angiography by multidetector computed tomography (MDCT). This was a retrospective study of 232 asymptomatic individuals, referred for a cardiovascular health checkup that ...
Miyairi Satoshi S Department of Cardiovascular Surgery, Seirei Hamamatsu General Hospital, Hamamatsu, - - 2014
Despite improvements in bioprosthetic valve function, increased human life-expectancy has led to a growing number of bioprosthetic valve deterioration cases requiring reoperation. We report 2 cases of primary tissue failure of a bioprosthetic valve, which were treated by mitral valve replacement using the valve-on-valve method. The reasons for the reoperations ...
Qiao Aike A a Center of Cardiovascular Medical Engineering, College of Life Science and Bioengineering, Beijing University of Technology , Beijing , P.R. - - 2014
It was found that bypass graft alone could achieve great effects in treating aortic dissection. In order to investigate the mechanical mechanism and the haemodynamic validity of the bypassing treatment for DeBakey III aortic dissection, patient-specific models of DeBakey III aortic dissection treated with different bypassing strategies were constructed. One ...
Lee Chang-Joon CJ The Australian School of Advanced Medicine, Macquarie University, Sydney, NSW, - - 2014
Flow-diverting stents occlude aneurysms by diverting the blood flow from entering the aneurysm sac. Their effectiveness is determined by the thrombus formation rate, which depends greatly on stent design. The aim of this study was to provide a general framework for efficient stent design using design optimization methods, with a ...
Chiastra Claudio C Laboratory of Biological Structure Mechanics (LaBS), Department of Chemistry, Materials and Chemical Engineering "Giulio Natta", Politecnico di Milano, - - 2014
Although stenting is the most commonly performed procedure for the treatment of coronary atherosclerotic lesions, in-stent restenosis (ISR) remains one of the most serious clinical complications. An important stimulus to ISR is the altered hemodynamics with abnormal shear stresses on endothelial cells generated by the stent presence. Computational fluid dynamics ...
Patel Tejas T Apex Heart Institute, Ahmedabad, India; Department of Cardiology, Sheth V.S. General Hospital and Smt. N.H.L. Municipal Medical College, Ahmedabad, 380 006, - - 2014
Objectives: The aim of this review is to discuss different methods of working through subclavian, innominate and aortic arch anatomical challenges in order to increase the success rate of transradial approach (TRA). Background: Anatomical challenges in the subclavian, innominate and aortic arch regions are important reasons for failure of TRA. ...
Lu L L Department of Medical Imaging, Jinling Hospital, Medical School of Nanjing University, Nanjing, - - 2014
Objective: To evaluate dual-energy CT (DECT) findings of pulmonary ischaemic-reperfusion injury (PIRI) and its pathophysiological correlation in the canine model. Methods: A PIRI model was established in 11 canines, utilizing closed pectoral balloon occlusion. Two control canines were also included. For the PIRI model, the left pulmonary artery was occluded ...
Gupta Ajay A From the Departments of Radiology (A.G., H.B., P.C.S.) and Neurology (H.K., A.M.), Weill Cornell Medical College, NewYork-Presbyterian Hospital, New York; Department of Public Health, Weill Cornell Medical College, New York, NY (A.P., A.D., P.C.S.); and Department of Neurology, Columbia University Medical Center, NewYork-Presbyterian Hospital, New York - - 2014
Increasing evidence suggests that carotid artery imaging can identify vulnerable plaque elements that increase stroke risk. We correlated recently proposed markers, soft and hard plaque thickness measurements on axial computed tomography angiography source images, with symptomatic disease status (ipsilateral stroke or transient ischemic attack) in high-grade carotid disease. Soft plaque ...
Ferring Martin M 1 Department of Renal Medicine, Worcester Acute Hospitals NHS Trust, Worcester - - - 2014
<sec id="st1"><title>ABSTRACT</title> <bold><italic>Aim:</italic></bold> The aim of this article is to assess the accuracy of early clinical and ultrasound (US) examination in terms of predicting arteriovenous fistula (AVF) dialysis use. <bold><italic>Methods:</italic></bold> Physical and US examination of patent AVF was performed 4 weeks after fistula creation. AVF dialysis use was defined as ...
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