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Chang Ji-Eun - - 2008
Arterial and cardiac involvement of Behcet's disease is a rare but life threatening complication. The rupture of an arterial aneurysm might result in sudden death. We report a 54-year-old man with an established diagnosis of Behcet's disease who presented with multiple cardiovascular complications that eventually lead to his death. He ...
Celik Turgay - - 2009
Mechanical plaque sealing with coronary stents is an established way of treating culprit lesions in diseased coronary arteries. Even though coronary stents are invaluable tools for local treatment of the diseased coronary arteries, the high prevalence of pancoronary destabilization in patients with acute coronary syndromes (ACS) highlights the importance of ...
Chen Zhong - - 2009
Background Two single nucleotide polymorphisms (SNPs, rs10757278 and rs2383207) on chromosome 9p21 have been proved to be associated with myocardial infarction. We investigated whether these two genetic markers are determinants of early-onset coronary artery disease. Methods and results A total of 444 consecutive patients were studied including 212 cases with ...
Nichols Larry - - 2008
CONTEXT: Coronary artery aneurysm is an uncommon condition that can be a cause of death when it thromboses or ruptures. It is always associated with destruction of the tunica media, usually associated with atherosclerosis, and commonly associated with chronic inflammation. OBJECTIVE: To review the pathology, epidemiologic and clinical features, and ...
Girish Meenakshi - - 2008
Kawasaki syndrome is one of the commonest vasculitides in pediatric age group with devastating consequences if not treated early. Intravenous Gammaglobulin leads to rapid amelioration of clinical symptoms and significantly decreases the risk of development of coronary artery aneurysms. Occasionally, Kawasaki disease may be resistant to I/V IgG. We present ...
Schüpbach W M Michael - - 2008
Cardiogoniometry is a non-invasive technique for quantitative three-dimensional vectorial analysis of myocardial depolarization and repolarization. We describe a method of surface electrophysiological cardiac assessment using cardiogoniometry performed at rest to detect variables helpful in identifying coronary artery disease. Cardiogoniometry was performed in 793 patients prior to diagnostic coronary angiography. Using ...
Vogiatzi Konstantina - - 2008
INTRODUCTION: Interleukin 8 is a strong chemoattractant factor for neutrophils and T lymphocytes. We investigated the potential influence of two common polymorphisms of the interleukin-8 gene, -251A/T, and 781C/T on susceptibility to coronary artery disease. MATERIALS AND METHODS: The hypothesis was tested by screening for the prevalence of the above ...
Yeu Boon Kian - - 2008
The incidence of coronary artery involvement has fallen markedly following early gammaglobulin infusions in Kawasaki disease. Nevertheless such involvement may still occur and if giant coronary aneurysms develop they are more likely to lead to myocardial ischaemia. Two subjects are described who developed giant aneurysms, one of whom was subjected ...
Guérin Alain P - - 2008
Cardiovascular disease is a major cause of morbidity and mortality in patients with end-stage renal disease (ESRD). Macrovascular disease develops rapidly in ESRD patients and is responsible for the high incidence of left ventricular hypertrophy, ischemic heart disease, cerebrovascular accidents, and peripheral artery diseases. Occlusive lesions due to atheromatous plaques ...
Khositseth A - - 2008
Giant coronary artery aneurysms caused by Kawasaki disease are not common; however, they are one of the most serious complications and can be fatal. Here, we describe a 5-year-old girl with Kawasaki disease who initially had normal coronary arteries. Despite intravenous immunoglobulin, she developed progressive giant coronary artery aneurysms. Echocardiography ...
Harada Tomonori - - 2008
Kawasaki disease is a generalized vasculitis of unknown etiology that occurs predominantly in infants and young children. It is very important to prevent its cardiovascular manifestations, especially coronary artery lesions. Early treatment with intravenous immunoglobulin reduces cardiovascular sequelae, but some patients do not respond to this treatment, and they have ...
Pleym Hilde - - 2008
OBJECTIVES: To investigate whether perioperative Sonoclot analyses could identify differences in hemostatic function between a group of patients with unstable coronary artery disease treated with low-molecular-weight heparin until the evening before surgery and a group of patients with stable coronary artery disease not treated with low-molecular-weight heparin. DESIGN: Prospective and ...
Inoue Teruo - - 2008
Lipocalin-type prostaglandin D synthase (L-PGDS), which is responsible for the biosynthesis of prostaglandin (PG) D(2), has been found to be present in the atherosclerotic plaque of the human coronary artery and also to be detectable in human serum. This multicenter cooperative study was designed to establish the diagnostic value of ...
Codispoti Cindy - - 2008
Kawasaki disease is the most common cause of pediatric ischemic heart disease in the world, but it is unusual in adults. We present a case of Kawasaki disease in a young adult. This 20-year-old man presented with angina. Coronary angiography revealed aneurysmal obstructive lesions consistent with remote Kawasaki disease. The ...
Varma Raja - - 2008
Coronary angiography was performed because of chest pain in 198 patients (146 women, 52 men; mean age 66 years) who had dual-energy x-ray absorptiometry scans of the spine and left hip because of suspected osteoporosis or osteopenia. Of the 198 patients, 53 (27%) had osteoporosis, 79 (40%) had osteopenia, and ...
Goss Fredric L - - 2008
The purposes of this study were to identify a zone of normality based upon ratings of perceived exertion (RPE) and compare the RPE of women with coronary artery disease to this zone. 45 healthy women (34.8 +/- 9.1 yr.) completed a Bruce treadmill test. RPE were estimated during the last ...
Ohno Takayuki - - 2008
Coronary artery disease is the leading cause of death in diabetics; therefore, the main purpose of managing coronary artery disease in diabetics should be to lengthen life expectancy. Recent evidence demonstrates that the severity of diabetic retinopathy is associated with a graded, increased risk of death from coronary artery disease ...
Sinha Dhurjati Prasad - - 2008
Anginal symptoms are less predictive of abnormal coronary anatomy in women. The diagnostic accuracy of exercise treadmill test for obstructive coronary artery disease is less in young and middle aged women. High sensitive C-reactive protein has shown a strong and consistent relationship to the risk of incident cardiovascular events. Carotid ...
Kitamura A - - 2008
Kawasaki disease (KD) is an acute, self-limiting vasculitis that occurs in children of all ages, which was first described by Kawasaki in 1967. The fatal complication of KD is coronary artery involvement resulting in coronary artery aneurysms. We report on two adult cases with coronary artery aneurysms secondary to childhood ...
Turley A J - - 2008
The development of coronary artery disease involves a complex interplay between environmental and genetic factors, with premature coronary artery disease having a strong genetic component. We present the case a pair of monozygotic identical twins presenting near simultaneously with coronary artery disease and identical atherosclerotic lesions despite significant differences in ...
Patil Sushant
Although coronary artery aneurysms occur in Kawasaki disease, giant aneurysms are rare. We report a very large coronary artery aneurysm, measuring 25 mm and involving left anterior descending artery, in a 2-year-old child with Kawasaki disease. The challenges in management of such a patient have been highlighted.
George Anil - - 2008
Most incident coronary disease occurs in previously asymptomatic individuals who were considered to be at a lower risk by traditional screening methods. There is a definite advantage if these individuals could be reclassified into a higher risk category, thereby impacting disease outcomes favorably. Coronary artery calcium scores have been recognized ...
Niemiec Pawel - - 2008
BACKGROUND: Angiotensin II is produced primarily by angiotensin I-converting enzyme (ACE) within atherosclerotic lesions and ACE level in plaques correlates with the severity of vessel wall damage. Therefore, we investigated the possible association of ACE gene insertion/deletion (I/D) polymorphism and the severity of atherosclerosis, estimated on the basis of the ...
Abu-Shakra Mahmoud - - 2008
Atherosclerotic disease is common in systemic lupus erythematosus and is the result of multiple pathogenic mechanisms that include traditional risk factors as well as SLE-related factors. Endothelial dysfunction and arterial stiffness contribute significantly to the atherogenic process. Dobutamine stress echocardiogram has not been shown to detect subclinical coronary artery disease; ...
Borowski Andreas - - 2008
OBJECTIVE: The purpose of this study was to evaluate changes in native coronary arteries in patients undergoing repeat myocardial revascularisation late (>3 years) after primary coronary artery bypass grafting (CABG). METHODS: The angiographic images of 30 patients obtained at first and redo CABG were assessed for significant (>75%), short (<1 ...
Li Sung-Tse - - 2008
Facial palsy is an unusual complication associated with Kawasaki disease, with only a few published case reports. We report two patients with typical Kawasaki disease and facial palsy. Both had coronary artery aneurysms and were treated with intravenous immunoglobulin. The facial palsy resolved completely over the next several months in ...
Sonia Hammami - - 2008
Coronary artery disease is extremely rare in patients with Behçet's disease. We report the case of a patient with a history of Behçet's disease who was admitted in our hospital with instable angina pectoris. The patient's electrocardiogram was normal. Coronary angiography revealed aneurysm of the distal right coronary artery with ...
Patil Sushant - - 2008
Although coronary artery aneurysms occur in Kawasaki disease, giant aneurysms are rare. We report a very large coronary artery aneurysm, measuring 25 mm and involving left anterior descending artery, in a 2-year-old child with Kawasaki disease. The challenges in management of such a patient have been highlighted.
Ward R Parker - - 2008
Erectile dysfunction (ED) has been associated with a future risk of myocardial infarction, yet the findings on stress testing in men with ED and without previous coronary artery disease are unknown. Stress myocardial perfusion single-photon emission computed tomographic imaging (MPI) allows detection of coronary artery disease and predicts cardiovascular prognosis. ...
Kannam Hari - - 2008
The prevalence of >70% narrowing of 1, 2, or 3 major coronary arteries and of 3 major coronary arteries was investigated in 2,465 patients (1,437 men, 1,028 women; mean age 69 +/- 13 years) with severe, moderate, mild, or no mitral annular calcium (MAC) diagnosed by 2-dimensional echocardiography who underwent ...
Kikuta Ken-ichiro - - 2007
A 65-year-old male with moyamoya disease underwent surgical resection of a microbleed simultaneously with revascularization surgery. Histological examination identified several fragile arteries surrounding the microbleed. Microbleeds detected by T2*-weighted magnetic resonance imaging are considered to be a general marker of vascular vulnerability in cerebral angiopathy with a tendency to bleeding. ...
Bosevski M - - 2007
The scope of our study was to assess the prevalence of metabolic syndrome (MSy) and its components in the type 2 diabetic population with symptomatic coronary artery disease in a sample of the Macedonian population. 327 pts with type 2 diabetes and manifested coronary artery disease were randomly included in ...
Cha Seung-Hun - - 2007
OBJECTIVE: Coronary artery disease is caused by multiple genetic and environmental factors. The disease is also closely associated with cardiovascular conditions such as hypertension. In order to investigate any possible role of hypertension candidate genes in the disease development and progression, we examined the association of the polymorphisms of 31 ...
Tillin Therese - - 2008
BACKGROUND: To compare patterns of coronary artery disease in British South Asian and White European men. METHODS: 41 South Asian and 42 European men (mean age 64+/-9 years) with coronary artery disease were studied. All had similar symptoms. Vessel reference diameter and degree of stenosis were calculated using quantitative coronary ...
Termeer Maurice - - 2007
We present novel, comprehensive visualization techniques for the diagnosis of patients with Coronary Artery Disease using segmented cardiac MRI data. We extent an accepted medical visualization technique called the bull's eye plot by removing discontinuities, preserving the volumetric nature of the left ventricular wall and adding anatomical context. The resulting ...
Chen Mien-Cheng - - 2007
The aim of this study was to confirm that plasma interleukin (IL)-18 level is associated with the extent of coronary artery disease in unstable angina patients. Previous studies have shown that patients with unstable angina have significantly higher plasma IL-18 levels than healthy volunteers. However, the association between IL-18 and ...
Pearson Tamera Lea - - 2007
BACKGROUND: Recent studies indicate that the use of ankle-brachial index (ABI) measurements helps identify patients with peripheral arterial disease. Previous research also reveals a relationship between peripheral arterial disease and higher incidence of cardiac mortality and morbidity. PURPOSE: The purpose of this study was to investigate the correlation of a ...
Ozkan Suleyman - - 2007
Kawasaki disease is an acute vasculitis syndrome of unknown etiology that mainly affects small and medium-sized arteries, particularly the coronary arteries. This disease is rarely seen in infants and young people in Turkey. In this short report, we present a four-year-old patient who has Kawasaki disease associated with coronary artery ...
Thapa Rajoo - - 2007
We describe an occurrence of Kawasaki disease presenting in the neonatal period with multiple coronary aneurysms. Very few such presentations of this entity have been described in the literature and this is probably the youngest patient reported from India. We also highlight an atypical finding, thrombocytopenia during the second week ...
Choi Seong-Min - - 2008
Disappearance of resting tremor was observed in a 76-year-old patient with Parkinson's disease after a contralateral thalamic infarct involving the territory of the tuberothalamic artery. Based on the analysis of surgical data of Parkinson's disease patients, this might be explained by the lesion of the ventral lateral nucleus, which is ...
Bosevski M - - 2009
Endothelial dysfunction, per se, in coronary arteries can stratify a risk in coronary artery disease patients. Selected studies evaluating endotheliopathy as predictor of events in patients with type 2 diabetes, but without coronary artery disease. We hypothesized that peripheral endothelial dysfunction could predict prognosis of type 2 diabetic patients who ...
Tavora Fabio - - 2008
BACKGROUND: The accuracy of death certificates issued for out-of-hospital sudden deaths has been questioned. METHODS: We retrospectively studied a series of consecutive autopsies performed at two community hospitals. RESULTS: Fifty-four autopsies in which the deaths were sudden and that occurred outside the hospital were retained for study. The indication for ...
Hamilos Michalis - - 2008
Dextrocardia is a relatively rare congenital malposition in which the association with coronary artery disease is at the same frequency as in the general population. Previous reports have shown successful attempts at treating percutaneously patients with dextrocardia and coronary artery disease. We report the case of a patient with dextrocardia ...
Chughtai Aamer - - 2007
A wide spectrum of acute cardiovascular disorders is seen in patients who are hospitalized in a critical care setting. Imaging plays a central role in the diagnosis and management of these conditions. The most frequently used imaging remains chest radiography; however, more advanced modalities, including coronary angiography, echocardiography, and radioisotope ...
Sadeghian Saeed - - 2007
BACKGROUND: The effects of opium consumption on coronary artery disease are still unknown. METHODS: A cross-sectional study was conducted on 2405 patients admitted to the Angiographic Ward at Tehran Heart Center from 7 May 2005 to 13 August 2005. RESULTS: After adjusting for conventional cardiovascular risk factors, opium consumption was ...
Nunes José Pedro L - - 2007
BACKGROUND: Mild renal dysfunction may be associated with increased cardiovascular morbidity and mortality. METHODS: The relation between estimated glomerular filtration rate (eGFR), as calculated from plasma creatinine at admission, and coronary artery disease burden (CADB), was studied in a cohort of 110 patients with acute coronary syndrome and coronary atherosclerosis. ...
Agarwal Rajiv - - 2007
PURPOSE OF REVIEW: Arterial stiffness is a sign of diffuse adventitial macrovascular disease. The purpose of the present review is to discuss, in patients with chronic kidney disease, the pathophysiology of increased arterial stiffness, the role of antihypertensive therapy on reduction of arterial stiffness, and the clinical ways by which ...
Usta Guc Belgin - - 2008
Kawasaki disease (KD) is an acute, febrile, and multisystem vasculitis of early childhood with a striking predilection for the coronary arteries. The most significant complication is coronary artery abnormalities, including coronary aneurysms. The etiology of KD remains unknown. Many infectious agents including viruses have been postulated as possible causes of ...
Dahdah N - - 2007
This is a case of an 11(1/2)-year-old diagnosed with Kawasaki disease at 6 months of age. Distal left main coronary aneurysm involving the proximal anterior descending and circumflex had progressed into a chronic total occlusion. We report the first application of a novel percutaneous technique using the CROSSER catheter system ...
Dwivedi Shridhar - - 2008
Cannabis is a common substance of drug abuse among the young adults because of its euphoric and addictive effects. The pathophysiological effects of cannabis smoking and its relation to adverse cardiovascular events are well known. However, the relative contribution of cannabis smoking when combined with tobacco smoking to coronary artery ...
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