Search Results
Results 601 - 650 of 925
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Ramos C E - - 1995
Priapism associated with sickle cell disease is classically described as a low flow state. We report 2 cases of high flow priapism associated with sickle cell disease. High flow priapism has previously been reported almost exclusively in patients with traumatic rupture of the cavernous artery. Neither of our patients had ...
Amaro A - - 1995
BACKGROUND: Recent studies suggest that leucocyte elastase is involved in the pathogenesis of atherosclerosis. The objective of this study was to characterize the role of leucocyte elastase in arterial disease in women. METHODS: Forty-two women underwent coronary angiography because of chest pain or valvulopathy. Twenty-three showed no signs of lesions ...
Hoshi K - - 1995
Plasma thrombomodulin (TM) levels in coronary sinus blood were measured in 15 patients with coronary artery disease who underwent elective PTCA (group A). TM was also measured in eight patients with coronary artery disease (group B) and six patients without coronary artery disease (group C), who only underwent diagnostic coronary ...
Heinrich J - - 1995
We investigated the vessel status of coronary and peripheral arteries and those arteries supplying the brain in 929 consecutive male patients admitted to a coronary rehabilitation unit. The severity of coronary atherosclerosis was scored using coronary angiography. Changes in extracranial brain vessels and manifest cerebrovascular disease (CVD) were determined by ...
Leone O - - 1995
In the past different terms have been used to define the vascular malformations of Dieulafoy's disease--for example, calibre persistent artery of the stomach, cirsoid aneurysm and gastric atherosclerosis. A case of Dieulafoy's disease is described in a 41 year old man, who presented with symptoms of anaemia and melaena, with ...
Atmer B - - 1995
The prevalence of peripheral vascular disease in patients with coronary artery disease has been investigated in many different ways and depends on the diagnostic methods and the definition of the atherosclerotic manifestations in the different vascular beds. In this study we used the non-invasive methods digital volume pulse plethysmography and ...
Saga T - - 1995
We report a case of Kawasaki disease in a Japanese boy who developed combined aneurysms and stenoses in both the coronary and iliac arteries. The boy underwent coronary artery bypass grafting using the left internal thoracic artery at the age of 7 years. The lower abdominal aorta and both common ...
O'Brien T - - 1995
The aim of this study was to examine the role of HDL subparticles with apolipoprotein (apo) A-I alone (LpA-I) and with apoA-I and apoA-II (LpA-I/A-II) in predicting coronary artery disease. Concentrations of these HDL subparticles were compared in 184 subjects with angiographically confirmed significant coronary artery disease (> 50% stenosis ...
Bakalova R - - 1995
Oxidative modifications of blood serum in humans with and without coronary artery disease were investigated. Four parameters were analyzed: the intensity of serum fluorescence, which is indicative of the content of lipofuscine-like lipid peroxidation products; the content of thiobarbituric acid-reactive substances; the lag-phase of serum oxidation by azo-compounds; and the ...
Malinow M R - - 1995
Homocysteine (HCY), which is derived from the intracellular metabolism of methionine, is exported into plasma, where it circulates mostly in oxidized forms (i.e., homocystine and cysteine-HCY disulfide) and mainly bound to proteins. Concentrations of total HCY, or homocyst(e)ine [H(e)], are increased in 15-40% of patients with coronary, cerebral, or peripheral ...
Takahashi N - - 1995
Among the 302 children with Kawasaki disease (KD) who were evaluated by angiography from 1973 through 1992, 9 (3.0%) had either an occlusion (OC) or segmental stenosis (SS) of the right coronary artery. The interval from the onset of KD to the recognition of OC or SS ranged from 0.5 ...
Raungratanaamporn O - - 1995
The prevalence of coronary artery disease in valvular disease was 10.9 per cent. The prevalence of coronary artery disease was more common in males, increasing age, aortic valvular disease and mitral regurgitation with chest pain, other types of valvular lesions did not correlate with the presence of coronary artery disease. ...
Rihal C S - - 1995
BACKGROUND: Among patients with combined coronary artery and peripheral vascular disease, long-term benefits of surgical therapy compared with medical therapy for coronary artery disease are unknown. METHODS AND RESULTS: Using prospectively collected data from the Coronary Artery Surgery Study registry, we performed a retrospective cohort analysis of 1834 patients (mean ...
Rho R - - 1995
Background: There is compelling evidence that coronary atherosclerosis represents a chronic active process characterized by inflammation, impaired fibrinolysis, intermittent plaque rupture, and luminal thrombosis. Identifying readily measurable plasma markers of procoagulant activity may have an important role in both tracking and understanding the natural history, as well as in defining ...
Malinow M R - - 1994
Homocysteine is a thiol-containing amino acid resulting from demethylation of methionine. The free and protein-bound forms of the amino acid and derived disulfides are called homocyst(e)ine [H(e)]. Multiple studies have shown elevated H(e) levels in patients with coronary, cerebrovascular, or peripheral arterial diseases; this association is frequent and independent of ...
Chao C L - - 1994
Dipyridamole thallium-201 imaging, using single-photon emission computed tomography, was evaluated for its safety and diagnostic efficacy in 109 patients with angiographically documented coronary artery disease and 35 normal subjects. The most common side effects after the intravenous administration of dipyridamole thallium-201 (0.56 mg/kg) included chest pain in 41 patients, dizziness ...
Tanabe T - - 1994
We devised a nine-lead Holter monitor system with a lead-switching technique to record electrocardiograms from multiple sites in the anterior and the posterior or lateral chest. Leads CM1 to CM6, high lateral (HL), low lateral (LL), and low posterior chest (LB) were used. The sensitivity, specificity, and predictive accuracy of ...
Senior R - - 1994
The relative value of exercise electrocardiography, simultaneous dobutamine technetium 99m-sestamibi (MIBI) single-photon-emission computerized tomography (SPECT), and echocardiography were evaluated for the diagnosis of coronary artery disease in patients with chest pain. Sixty-one consecutive patients underwent exercise electrocardiography and simultaneous graded dobutamine echocardiography and MIBI imaging. All patients underwent coronary arteriography. ...
Cramer M J - - 1994
AIM: The purpose of this study was a head-to-head comparison of tomographic imaging (SPECT) with technetium-99m (Tc-99m)-sestamibi and thallium-201 (Tl-201) using dipyridamole-low-level bicycle exercise stress for the assessment of coronary artery disease. METHODS: We studied 38 consecutive patients referred for the evaluation of chest pain who had undergone coronary angiography. ...
Meyer B J - - 1994
Prevention of thrombus formation and embolization remains a therapeutic challenge. Recent advances in the treatment of arterial thromboembolic disease include prevention of thromboembolism in patients with nonrheumatic atrial fibrillation with warfarin or aspirin, and combined therapy with low-dose aspirin, and anticoagulants for prosthetic heart valves and coronary artery disease. The ...
Mautner S L - - 1994
PURPOSE: To investigate the potential to predict coronary artery disease with electron beam computed tomography (CT). MATERIALS AND METHODS: Fifty heart specimens were examined with electron beam CT and histomorphometric techniques to measure calcific deposits as a percentage of blockage. RESULTS: In group A specimens (from cadavers of patients with ...
Di Salvo T G - - 1994
Antithrombotic therapy has assumed a central role in the therapy of the acute coronary syndromes and chronic coronary artery disease. The theoretical rationale for antithrombotic therapy, and the established and evolving roles of antiplatelet agents and anticoagulants in coronary disease are reviewed. Emphasis is focused on new antithrombotic agents and ...
Prince C R - - 1994
Atrial pacing and dipyridamole transesophageal echocardiography have been shown to be sensitive and specific tests for the detection of coronary artery disease. However, the sensitivity and specificity of dobutamine transesophageal echocardiography have not been reported. The purpose of this study was to determine the feasibility, sensitivity, and specificity of dobutamine ...
Schechter D - - 1994
The cardiovascular risk of concurrent coronary artery disease in patients undergoing bone marrow transplantation (BMT) is not well known. We present a case of a 32-year-old male Hodgkin's disease patient with prior chemotherapy and radiotherapy, who underwent autologous BMT. His underlying single vessel coronary artery disease was well documented and ...
Ostojic M - - 1994
OBJECTIVES: This study was designed to assess the clinical, hemodynamic and diagnostic effects of the addition of dobutamine to dipyridamole echocardiography. BACKGROUND: Pharmacologic stress echocardiography with either dipyridamole or dobutamine has gained acceptance because of its safety, feasibility, diagnostic accuracy and prognostic power. The main limitation of the two tests ...
Albat B - - 1994
Kawasaki disease (KD) is an acute illness encountered in infancy and childhood. Cardiovascular complications of this syndrome are recognized as being part of the adult coronary artery disease population. Reported herein is the surgical treatment of multiple coronary artery aneurysms, severe stenotic lesions and thrombotic involvement of the coronary arterial ...
Takahashi N - - 1994
BACKGROUND: Technetium 99m tetrofosmin is a new 99mTc-labeled myocardial perfusion agent that can be labeled easily and provides excellent myocardial perfusion images. In addition, bolus administration of the tracer allows first-pass radionuclide ventriculography. METHODS AND RESULTS: This study examined the diagnostic value of combined assessment of regional perfusion by tetrofosmin ...
Olin J W - - 1994
Thromboangiitis obliterans (Buerger's disease) is an inflammatory obliterative, nonatherosclerotic, vascular disease that affects the small- and medium-sized arteries, veins, and nerves. It is causally related to tobacco use, although the exact mechanism is unknown. Its clinical presentation is manifested by distal arterial ischemia and superficial thrombophlebitis. Thromboangiitis obliterans usually becomes ...
Winer-Muram H T - - 1994
Multiple pulmonary artery aneurysms associated with pulmonary artery thromboses and infarctions are uncommon and occur almost exclusively in Behçet's disease (BD). Because of the rarity of the disease outside endemic areas, sporadic cases may go unrecognized. We report two African-American men with thoracic vascular manifestations of BD. In one patient ...
Zugibe F T - - 1993
The etiology of sudden unexpected death in young and middle age adults is frequently listed as undetermined, thereby causing much grief and fear among family members. When careful, methodical autopsies were performed, a significant number of cases of hypoplastic coronary artery disease (HCAD) were found where no other etiological factor ...
Di Maio V J - - 1993
Acute coronary thrombosis does not play a major role in the causation of sudden unexpected death due to coronary artery disease. In a study of 500 consecutive autopsies of individuals aged 20-99 years, dying suddenly and unexpectedly of coronary artery disease, only 67 (13.4%) showed an acute thrombosis. In contrast, ...
Porter T R - - 1993
OBJECTIVES: We hypothesized that intravascular ultrasound may identify significant coronary artery narrowing in the mildly diseased coronary artery of patients with insignificant or one- or two-vessel coronary artery disease. BACKGROUND: Necropsy studies have revealed that coronary angiography may underestimate stenosis severity in vessels that appear mildly diseased. Intravascular ultrasound has ...
Rasheed Q - - 1993
Coronary endothelial function, arterial distensibility, and elastic recoil were assessed in various groups of patients using intracoronary ultrasonic (ICUS) imaging. We found evidence of endothelial dysfunction in patients with risk factors for coronary artery disease even before atherosclerosis could be detected angiographically or with sensitive ICUS imaging. There was marked ...
Sahi N - - 1993
Serum lipids, lipoproteins, apolipoproteins (A-1 and B) were determined in 225 patients with angiographic evidence of coronary artery disease (having abnormal coronary angiogram and positive exercise stress test), and 112 patients without any clinical and/or angiographic evidence of coronary artery disease. The variable with the strongest association with coronary artery ...
Akay M - - 1993
A nonlinear neural network classifier was applied to noninvasive acoustic detection of coronary artery disease; the classifier included a feature vector, derived from diastolic heart sounds, and a multi-layered network trained by the backpropagation. The feature vector is based on the linear prediction coefficients of the autoregressive method after an ...
Chang B B - - 1993
Diabetic foot lesions are caused by neurologic, orthopaedic, immunologic, and vascular derangements. Whereas some lesions may be initially caused by trauma and others directly caused by vascular disease, improvement of arterial perfusion often plays an important role in the successful salvage of these limbs. Fortunately, in the last several years, ...
Kang S S - - 1993
BACKGROUND: To determine whether or not a moderate genetic defect of homocysteine metabolism is associated with the development of coronary artery disease, we studied the prevalence of thermolabile methylenetetrahydrofolate reductase, which is probably the most common genetic defect of homocysteine metabolism. METHODS AND RESULTS: Three hundred thirty-nine subjects who underwent ...
Casey F - - 1993
In the period 1985-1991 inclusive, forty five cases of Kawasaki Disease were identified in Northern Ireland. The number of cases increased each year until 1988 when the incidence was 19 per million population under 16 years, the highest reported for any region in the United Kingdom (data from British Paediatric ...
Norris L P - - 1993
TPE is a new diagnostic technique that uses simultaneous graded transesophageal left atrial pacing and biplane transesophageal echocardiography for the detection of pacing-induced wall motion abnormalities. In a prospective study 30 patients underwent biplane TPE, dipyridamole thallium-201 single-photon emission computed tomography (SPECT), and coronary arteriography. The sensitivity (86% vs 95%, ...
Taylor S M - - 1993
Patients with aortic aneurysms frequently have concomitant coronary artery disease, which carries the potential for significantly increased perioperative morbidity. Most cases of severe surgically correctable coronary artery disease can and should be treated by a separate operation before aneurysmectomy to lower operative cardiac morbidity and enhance long-term survival. Infrequently, a ...
Akay Y M - - 1993
Previous studies have indicated heart sounds may contain information useful in the detection of occluded coronary arteries. During diastole, coronary blood flow is maximum, and the sounds associated with turbulent blood flow through partially occluded coronary arteries should be detectable. In order to detect such sounds, recordings of diastolic heart ...
Suzuki A - - 1993
Coronary arteriograms obtained in 1,392 patients from a cohort of 4,562 with Kawasaki disease showed 395 to have coronary arterial lesions. The specific lesions, known as segmental stenoses, were observed in 62 patients, involving 68 coronary arterial branches. The lesions involved the right coronary artery in 56 cases (14.2% of ...
Lu C P - - 1993
From April 1983 to August 1991, 70 cases of Kawasaki disease were admitted to Taiwan Provincial Tao-Yuan General Hospital. Fifty-seven patients treated with aspirin 80-100 mg/kg/day alone during the acute phase were followed by two-dimensional echocardiography for two weeks to two years. Twelve cases (21%) complicated with coronary arterial aneurysm ...
Hecht H S - - 1993
The abilities of peak exercise (PEAK) stress echocardiography versus postexercise (POST) stress echocardiography to detect coronary artery disease were evaluated in 136 consecutive patients undergoing supine bicycle stress echocardiography and coronary arteriography: 42 (31%) had normal coronary vessels, 38 (28%) had single-vessel disease, 34 (25%) had double-vessel disease, and 22 ...
Stone P H - - 1993
Previous studies of the natural history of coronary disease generally relied on estimates of percent stenosis derived from visual assessment of the coronary angiogram. In a study of 26 patients, serial quantitative angiography was performed 3 years apart to determine changes in both absolute measurements of the luminal diameter and ...
Klassen T P - - 1993
OBJECTIVE: To determine the costs and clinical outcomes of three alternative treatments of the acute phase of Kawasaki syndrome: aspirin alone; low doses of intravenously administered immune globulin (IVIG-LD), 400 mg/kg per dose for 4 days; and high doses of intravenously administered immune globulin (IVIG-HD), 2.0 gm/kg for one dose. ...
Hecht H S - - 1993
OBJECTIVES: The objective of this study was to determine the accuracy of digital supine bicycle stress echocardiography, a new technique for evaluating coronary artery disease during peak exercise. BACKGROUND: Prior stress echocardiographic techniques have not utilized peak exercise imaging to determine the extent and location of coronary artery disease. METHODS: ...
Kondo C - - 1993
Noninvasive monitoring of the process of coronary occlusion will probably aid in determining the timing of therapeutic interventions for Kawasaki disease. A pair study of coronary angiography and thallium scintigraphy after dipyridamole infusion-single-photon emission computed tomography with dipyridamole infusion (Dp-SPECT) was repeated at least twice at intervals of several years ...
Priestley K A - - 1993
Patients with diffuse coronary artery disease present a significant management problem. It has been proposed that diffuse coronary disease is unsuitable for balloon angioplasty and surgical treatment is not ideal either. We review the evidence that coronary balloon angioplasty is not a suitable treatment for diffuse coronary disease and examine ...
Sharma S - - 1993
We report a patient with nonspecific aortoarteritis (Takayasu's disease) in whom occlusion of the right upper lobe pulmonary artery was associated with collateral flow from the left circumflex coronary artery. Coronary to pulmonary artery collaterals are rare in this disease but have important clinical implication because of their ability to ...
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