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Kuetting Maximilian M Department of Cardiovascular Engineering, Institute of Applied Medical Engineering - Helmholtz Institute - RWTH Aachen University, Pauwelsstraße 20, 52074 Aachen, - - 2014
Minimally invasive, catheter-based treatment of valvular dysfunction has become an integral part of clinical routine. As left heart valvular disease is much more common and thus commercially of interest, transcatheter solutions for the treatment of aortic and mitral valvular defects were the first to become broadly clinically available, while even ...
Carstensen Helle Gervig HG Department of Cardiology, Gentofte Hospital, University Hospital of Copenhagen, Niels Andersens Vej 65, 2900, Copenhagen, Denmark, - - 2014
Longitudinal deformation has been shown to deteriorate with progressive aortic stenosis as well as ischemic heart disease. Despite that both conditions share risk factors and are often coexisting, studies have not assessed the influence on longitudinal deformation for both conditions simultaneously. Thus the purpose of this study was to evaluate ...
de Haan Judy B - - 2014
Restenosis after balloon angioplasty and stenting (BAS) remains an unsolved clinical dilemma for patients with coronary artery disease. A better understanding of the mechanisms that drive this phenomenon is likely to lead to more effective treatments. In this issue of the JCI, Ali et al. uncover a critical redox axis ...
Kang Ming-Yuan MY Cardiovascular Center of Taichung Veterans General Hospital, Taichung, - - 2014
A 73-year-old man with a history of severe aortic regurgitation underwent aortic valve replacement with a bioprosthesis. Nine years later, he presented with heart failure and was diagnosed with chronic type A dissection and severe aortic stenosis. During surgery, a fistula from the ascending aortic aneurysm to the right atrium ...
Piñón Miguel M Department of Cardiac Surgery, Hospital Meixoeiro, Complejo Hospitalario Universitario de Vigo, Vigo, Spain - - 2014
Bioprosthetic valves are used in aortic valve replacement to avoid lifelong anticoagulation. Bovine pericardial valves have excellent haemodynamics and equivalent freedom from reoperation compared with a porcine bioprosthesis [ 1]. However, early failure (parastent post-cusp tear) can take place due to mechanical stress. We report an acute structural failure on ...
Mason Justin C JC Vascular Sciences and Rheumatology, Imperial Centre for Translational and Experimental Medicine, National Heart and Lung Institute, Imperial College London, Hammersmith Hospital, London, - - 2014
Open and endovascular surgery remains important in the management of Takayasu arteritis. This review summarizes the indications and approaches available, the evidence for them and recent advances. The outlook in Takayasu arteritis has improved over the last decade, reflecting earlier diagnosis, increased use of noninvasive imaging and combination immunotherapy. This ...
Morsolini M M Department of Clinical-Surgical, Diagnostic and Pediatric Sciences, Division of Cardiac Surgery Heart and Lung Transplantation and Pulmonary Endarterectomy Unit, University of Pavia School of Medicine, Pavia, Italy - - - 2014
Chronic thromboembolic pulmonary hypertension (CTEPH) is a progressive disease due to the incomplete resolution of pulmonary emboli, leading to right heart failure, with a poor survival. Pulmonary endarterectomy (PEA) is the operation of choice for CTEPH. As there are no well-defined criteria to discriminate surgically accessible from inaccessible obstructive lesions, ...
Dragu Robert R Department of Cardiology, Rambam Health Care Campus and the Ruth and Bruce Rappaport Faculty of Medicine, Technion, Israel Institute of Technology, Haifa, - - 2014
Reactive pulmonary hypertension (PH) is a severe form of PH secondary to left-sided heart failure (HF). Given the structural and functional abnormalities in the pulmonary vasculature that occur in reactive PH, we hypothesized that pulmonary artery capacitance (PAC) may be profoundly affected, with implications for clinical outcome. We studied 393 ...
Reiter Gert G From Research and Development, Siemens AG, Healthcare Sector, Graz, Austria (G.R.); Division of General Radiology, Department of Radiology (U.R., M.F.), and Division of Pulmonology, Department of Internal Medicine (G.K., H.O.), Medical University of Graz, Auenbruggerplatz 9/P, A-8036 Graz, Austria; and LBI for Lung Vascular Research, Graz, Austria (G.K., - - 2014
Purpose To approximate the functional relationship between invasively measured mean pulmonary arterial pressure ( mPAP mean pulmonary arterial pressure ) and the phase-contrast magnetic resonance (MR) imaging-derived duration of vortical blood flow along the main pulmonary artery and to analyze its applicability for noninvasive diagnosis of pulmonary hypertension ( PH ...
Kaza Aditya K AK Department of Cardiac Surgery, Boston Children's Hospital, 300 Longwood Ave, Bader 273, Boston, MA 02115, - - 2014
Critical aortic stenosis with unicommissural valve in the neonate is a complex lesion. These neonates have varying degrees of development of left-sided structures of the heart. Treatment decision depends on the anatomic and functional nature of the aortic valve and other left-sided structures. This review presents the various treatment modalities ...
Lehnert Per P Department of Cardiothoracic Surgery, Rigshospitalet, Copenhagen University Hospital, - - 2014
Transit-time flow measurement (TTFM) is a commonly used intraoperative method for evaluation of coronary artery bypass graft (CABG) anastomoses. This study was undertaken to determine whether TTFM can also be used to predict graft patency at one year postsurgery. Three hundred forty-five CABG patients with intraoperative graft flow measurements and ...
Gerede Demet Menekse DM Department of Cardiology, Ankara University School of Medicine, Ankara, - - 2014
Coronary artery fistulas (CAF) are a rare cardiac anomaly that can be either congenital or acquired. CAFs have clinical significance because of complications such as dyspnea on exertion, congestive heart failure, and cardiac tamponade. The literature also contains case reports of CAF presenting as bacterial endocarditis. We describe a 31-year-old ...
Xiao Yanyan Y Department of Pediatric Cardiology, Beijing Anzhen Hospital, Capital Medical University, Beijing 100029, - - 2014
The anomalous origin of the left coronary artery (LCA) from the pulmonary artery (ALCAPA) and congenital left main coronary artery atresia (CLMCA-A) are two kinds of very rare coronary heart diseases which affect heart function profoundly. This study aimed to retrospectively illustrate the clinical features and therapy experience of ALCAPA ...
Kashiyama Noriyuki N Department of Cardiovascular Surgery, Osaka University Graduate School of Medicine, Yamadaoka, 2-2, Suita-city, Osaka, 565-0087, - - 2014
Recent evidence suggests that transcatheter aortic valve replacement (TAVR) is feasible for treating severe aortic valve stenosis (AS) in patients who are considered high risk for elective surgery. However, it is still unclear whether TAVR is a better option than surgical aortic valve replacement for severe AS with acute decompensated ...
Shiota Takahiro T Department of Medicine, Heart Institute, Cedars-Sinai Medical Center and University of California, Los Angeles, Los Angeles, CA, - - 2014
Three-dimensional (3D) echocardiography has been conceived as one of the most promising methods for the diagnosis of valvular heart disease, and recently has become an integral clinical tool thanks to the development of high quality real-time transesophageal echocardiography (TEE). In particular, for mitral valve diseases, this new approach has proven ...
Okiwelu Ngozichukwuka N Department of Cardiothoracic Surgery, Sir Charles Gairdner Hospital, Perth, Western Australia - - 2014
Pulmonary artery involvement has been reported in various degrees of complicated dissection of the ascending aorta. The prognosis remains poor without high-risk surgical intervention, but conservative management can be considered in high-risk cases. We report a case of nonoperative management of an octogenarian who presented with a contained rupture of ...
Villablanca Pedro A PA Pedro A Villablanca, Shashvat Sukhal, Oscar Maitas, Afiachuukwu Onuegbu, Juan M Muñoz-Peña, Ajay Joseph, Carlos Requena, Divyanshu Mohananey, Department of Internal Medicine, John H. Stroger, Jr. Hospital of Cook County, Chicago, IL 60612, United - - 2014
Abnormal connections between the ascending aorta and the cardiac chambers are rare, especially in the context of right-sided infective endocarditis (IE). Transthoracic echocardiography (TTE) with color-flow Doppler, transesophageal echocardiography (TEE), or both may be required for diagnosis. We present the case of a woman admitted with right-sided heart failure (HF) ...
Wang Hong - - 2014
Partial anomalous venous connection (PAPVC) is a rare congenital heart disease where the blood flow from one or more pulmonary veins (but not all) returns to the right atrium or systemic venous circulation and is often associated with a sinus venosus atrial defect (SVD). Transthoracic echocardiography (TTE) can provide limited ...
Steffensen Thora S TS 1Tampa General Hospital , Tampa, FL , - - 2014
Congenital coronary artery anomalies are rare. Pathologists are exposed to those in mainly two settings; in association with sudden death and usually extreme exercise in young adults, and in association with complex congenital heart disease in the pediatric and perinatal population. Pediatric pathologists, other pathologists and pathologists' assistants performing pediatric ...
Hammel James M JM Pediatric Cardiology, University of Nebraska Medical Center and Children's Hospital and Medical Center, Omaha, - - 2014
We present the anatomic constellation of mitral stenosis/aortic atresia variant of hypoplastic left heart syndrome, Ebstein's anomaly, and partial anomalous pulmonary venous return, an exceeding rare congenital heart defect. Prenatal echocardiography led to concern about the capacity of the right ventricle to increase cardiac output with lung expansion and pulmonary ...
Grzegorek Irmina I 1 Regional Specialized Hospital in Wroclaw, Research and Development Center , Wroclaw, Poland - - 2014
Abstract Twenty-six iliac artery segments were divided in two groups: atherosclerotic (A) and nonatherosclerotic (NA). Expression of LYVE-1, VEGF-C, VEGF-D, and CCR7 receptor were studied with immunohistochemistry (IHC) and Western blot (WB). IHC was performed on 26 samples of iliac arteries obtained from deceased 19 organ donors. The samples were ...
Channing Alexandra A The Fetal Heart Program at the Cardiac Center at the Children's, Hospital of Philadelphia, Philadelphia, PA, - - 2014
Aneurysm of the atrial septum (AAS) with excessive excursion of septum primum into the left atrium is an uncommon, relatively benign fetal condition associated with impediment to left ventricular (LV) filling and the appearance of a slender but apex-forming LV on fetal echocardiography. Impediment to filling can be severe creating ...
Tessitore Elena E Division of Cardiology, University Hospital of Geneva, Geneva, - - 2014
Quadricuspid aortic valve (QAV) is a rare congenital heart defect, often related to severe aortic regurgitation, and usually detected by echocardiography or at the time of aortic valve surgery. We report a case of an interesting and extremely rare variant of "false" QAV, detected preoperatively by transthoracic and transesophageal echocardiography, ...
Roden Anja C AC Department of Laboratory Medicine and Pathology, Mayo Clinic Rochester, MN, - - 2014
Pulmonary hypertension is a disease that is characterized by an increased pulmonary artery pressure and often results in right ventricular failure. Patients of any age might present with exertional dyspnea and fatigue, but clinical signs and symptoms can sometimes be difficult to recognize. Therefore, histopathology might become critical for the ...
Cataldo S S Adult Congenital Heart Disease Unit Bristol Heart Institute, Bristol, UK - - - 2014
There are a wide variety of coronary artery anomalies and disease in adults with congenital heart disease (CHD). In fact, the increasing burden of acquired coronary artery disease (CAD) has to be considered in addition to congenital abnormalities of the coronary arteries, isolated or associated to other congenital diseases. This ...
Soyer T T Faculty of Medicine, Department of Pediatric Surgery, Hacettepe University, Ankara, - - 2014
Prostaglandin E1 (PGE1) is widely used in ductus-dependant congenital heart disease to maintain the patency of ductus. Hypertrophic pyloric stenosis (HPS) due to gastric mucosal proliferation is a rare complication of prolonged PGE infusion. A male newborn who developed HPS during PGE1 infusion is presented to discuss the clinical features ...
Chen Heidi I - - 2014
Coronary arteries (CAs) stem from the aorta at 2 highly stereotyped locations, deviations from which can cause myocardial ischemia and death. CA stems form during embryogenesis when peritruncal blood vessels encircle the cardiac outflow tract and invade the aorta, but the underlying patterning mechanisms are poorly understood. Here, using murine ...
Lu Qixiu Q Department of Ultrasound, Shandong Jining No.1 People's Hospital, Jining, 272011, Shandong, China, - - 2014
The main objective of this study is to investigate the relationship between ascending aorta elasticity and the severity of coronary artery stenosis in essential hypertensive patients with coronary heart disease (CHD) using M-mode and tissue Doppler echocardiography. A total of 184 hypertensive patients with CHD were enrolled. Patients were divided ...
Zimmet Jeffrey J San Francisco VA Medical Center, 4150 Clement Street, Cardiology 111C, San Francisco, CA 94121 USA. - - 2014
This is the first reported case of partial aortic valve and annulus rupture during transcatheter aortic valve replacement, and its successful management through percutaneous means. It stresses the fact that even severe procedural complications can often be treated by a heart team endovascularly, without requiring sternotomy.
Delius Ralph E RE Department of Cardiovascular Surgery, Children's Hospital of Michigan, Detroit, Michigan. Electronic address: - - 2014
Three-patch repair of supravalvar aortic stenosis is a widely accepted surgical approach for this congenital heart lesion. We describe an unusual complication of this approach, which resulted in ischemia in the left anterior coronary artery distribution. Subtle oversizing of the left sinus of Valsalva patch led to kinking of the ...
Anderson R D RD Department of Cardiology, St Vincent's Hospital, Melbourne, Victoria, - - 2014
Interferon-alpha treatment is a rare cause of pulmonary arterial hypertension (PAH). We report a case of a 43-year-old man treated for chronic hepatitis C infection complicated by decompensated right heart failure diagnosed with PAH and external coronary artery compression secondary to a dilated pulmonary trunk. The novel complication of extrinsic ...
Salgado Rodrigo A RA From the Departments of Radiology (R.A.S., L.A., B.J.O.d.B., P.M.P.), Cardiology (B.S., P.L.V.H., C.V., J.B.), and Cardiothoracic Surgery (I.R.), Antwerp University Hospital, Wilrijkstraat 10, 2650 Edegem-Antwerp, Belgium; and Department of Radiology, Department of Medical Imaging, St Paul's Hospital, University of British Columbia, Vancouver, BC, Canada - - 2014
Aortic valve stenosis is the most common valvular heart disease in the Western world. When symptomatic, aortic valve stenosis is a debilitating disease with a dismal short-term prognosis, invariably leading to heart failure and death. Elective surgical valve replacement has traditionally been considered the standard of care for symptomatic aortic ...
Koo Hyun Jung HJ From the Department of Radiology and Research Institute of Radiology (H.J.K., D.H.Y., S.Y.O., J.W.K., T.H.L.), Division of Cardiology (D.H.K., J.K.S.), and Department of Cardiovascular Surgery (J.W.L., C.H.C.), Cardiac Imaging Center, Asan Medical Center, University of Ulsan College of Medicine, Asanbyeongwon-gil 86, Seoul 138-736, South - - 2014
Mitral valve prolapse (MVP), the most frequent cause of severe nonischemic mitral regurgitation, often warrants surgical or interventional valve repair. The severity of mitral regurgitation positively correlates with the development of heart failure and death. Even in patients who are asymptomatic, severe mitral regurgitation causes higher rates of death, heart ...
Alzahrani Ahmed M AM Congenital Heart Disease Section, Department of Medicine, Prince Sultan Military Medical City, Riyadh, Kingdom of Saudi - - 2014
A 38-year-old male was diagnosed with unrepaired ventricular septal defect associated with severe pulmonary arterial hypertension, cyanosis, and significant exercise intolerance. His echocardiogram showed right ventricular dysfunction and moderate pericardial effusion with no signs of cardiac tamponade. He was treated with an intensive course of inhaled iloprost and sildenafil. He ...
Poynter Jeffrey A JA Congenital Heart Surgeons Society Data Center, The Hospital for Sick Children, Toronto, Ontario, Canada Department of Surgery, Indiana University School of Medicine, Indianapolis, IN, - - 2014
Anomalous aortic origin of a coronary artery (AAOCA) encompasses a wide morphologic spectrum, which has impeded consensus regarding indications for the diverse repair strategies. We constructed a profile of current surgical techniques and explore their application to morphologic variants. Patients <30 years old (n = 113) with isolated AAOCA who ...
Kariyappa Mallesh M Department of Cardiology, Sri Jayadeva Institute of Cardiovascular Sciences and Research, Bengaluru, Karnataka, - - 2014
Congenital absence of the pulmonary valve is a rare congenital cardiac malformation, usually seen in association with tetralogy of Fallot. Patients generally present early in life with respiratory distress or recurrent respiratory tract infections, failure to thrive, cyanosis, infective endocarditis, or heart failure. Isolated absent pulmonary valve is quite rare ...
Kim Young Sam YS Department of Thoracic and Cardiovascular Surgery, Inha University - - 2014
Diffuse refractory vascular spasms associated with coronary bypass artery grafting (CABG) are rare but devastating. A 42-year-old male patient with a past history of stent insertion was referred for the surgical treatment of a recurrent left main coronary artery disease. A hemodynamic derangement developed during graft harvesting, necessitating a hurried ...
Ando Katsutoshi K 1 Department of Respiratory Medicine, Juntendo University Graduate School of Medicine, 2-1-1 Hongo, Bunkyo-Ku, Tokyo 113-8421, Japan ; 2 Department of Respiratory Medicine, Kameda Medical Center, 929 Higashi-cho, Kamogawa-City, Chiba 296-8602, Japan ; 3 Fukuoka Clinic, 7-18-11 Umeda, Adachi-Ku, Tokyo 123-0851, - - 2014
Patients with chronic obstructive pulmonary disease (COPD) manifest an excess of chronic co-morbidities and present a high prevalence of cardiovascular disease such as congestive heart failure and ischemic heart disease. Aortic aneurysm (AA) also shared the risks of those diseases and its rupture is an important cause of death. However, ...
Tomanek Robert J RJ Department of Anatomy and Cell Biology, Carver College of Medicine, The University of Iowa, Iowa City, IA, - - 2014
Background: Coronary anomalies are frequently associated with congenital cardiac defects. Accordingly, we tested the hypothesis that the development of the tunica media of coronary arteries/arterioles is compromised in mice with cardiac defects of the outflow tract (persistent truncus arteriosus, double outlet right ventricle and transposition of the great arteries) by ...
Zamorano Jose L JL University Hospital Ramón y Cajal, Madrid, - - 2014
Mitral regurgitation is a common valvular heart disease and its prevalence is expected to increase with population ageing. Percutaneous techniques for the treatment of mitral regurgitation are emerging as an alternative therapeutic option. However, the mitral valve is a complex structure, and a comprehensive understanding of the anatomy of the ...
Mylotte Darren D Department of Interventional Cardiology, McGill University Health Centre, Montreal, QC, Canada Department of Cardiology, Galway University Hospital, Galway, - - 2014
A comprehensive description of transcatheter heart valve (THV) failure has not been performed. We undertook a systematic review to investigate the aetiology, diagnosis, management, and outcomes of THV failure. The systematic review was performed in accordance with the PRISMA guidelines using EMBASE, MEDLINE, and Scopus. Between December 2002 and March ...
Abou Zahr Riad R Department of Pediatrics, section of Pediatric Cardiology, Yale University School of Medicine, New Haven, CT, - - 2014
Trans-catheter balloon angioplasty is a well-established treatment modality for pulmonary artery stenosis in children with congenital heart disease. We report a case of an unusual complication where a fistula developed between the left pulmonary artery and the left atrium during balloon angioplasty in a patient with history of tetralogy of ...
Huang C C Department of Rheumatology, Peking Union Medical College Hospital, Key Laboratory of Rheumatology and Clinical Immunology, Ministry of Education, Beijing, - - 2014
A 35-year-old female patient was diagnosed with pulmonary arterial hypertension (PAH) by right heart catheterization (RHC) in the 3rd month of systemic lupus erythematosus (SLE) duration with high disease activity. Through methylprednisolone pulse therapy, she got total recovery from PAH proven by repeat catheterization and follow-ups. This is the first ...
Loukas Marios M Department of Anatomical Sciences, St. George's University, Grenada, West Indies; Department of Anatomy, Varmia and Mazuria Medical School, Olsztyn, - - 2014
Coronary arteries have been extensively described and recognized by gross anatomic studies. However, in the clinical setting, the recognition of the conal artery is essential during coronary angiography, as well as certain congenital heart conditions such as tetralogy of Fallot. In order to provide a complete anatomic and physiologic correlation ...
Morsi Yosry S YS Biomechanics and Tissue Engineering Group, Faculty of Science, Engineering and Technology, Swinburne University of Technology, Melbourne - - - 2014
The occurrence of dysfunctional aortic valves is increasing every year, and current replacement heart valves, although having been shown to be clinically successful, are only short-term solutions and suffer from many agonizing long-term drawbacks. The tissue engineering of heart valves is recognized as one of the most promising answers for ...
Tanemoto Kazuo K Department of Cardiovascular Surgery, Kawasaki Medical School, 577 Matsushima, Kurashiki City, Okayama, 701-0192, Japan, - - 2014
For successful repeated valve replacement surgery, it is essential issue that the preoperative evaluation includes an assessment of the previous operation record, computed tomography (CT: including 3D-CT), ultrasound cardiography, coronary artery angiography, and so on. Although it is especially needed for repeated valve replacement surgery, setting up of the external defibrillation ...
D'Alto Michele M Department of Cardiology, Second University of Naples - Monaldi Hospital, Naples, - - 2014
Echocardiography is a key screening tool in the diagnostic algorithm of pulmonary arterial hypertension (PAH). It provides an estimate of right ventricular function and pulmonary artery pressure, either at rest or during exercise, and is useful in ruling out secondary causes of pulmonary hypertension (PH) such as left heart disease ...
Godinho Ana Rita AR Serviço de Cardiologia, Hospital de São João, Porto, Portugal. Electronic address: - - 2014
The authors present the case of a 68-year-old man with predominantly right heart failure in the context of severe aortic stenosis associated with pulmonary hypertension. Anemia was diagnosed which, after endoscopic study, was considered to be secondary to angiodysplasia and a diagnosis of Heyde syndrome was made. After valve replacement ...
Li Yang Y Department of Cardiovascular Surgery, West China Hospital, Sichuan University, Chengdu, Sichuan, People's Republic of - - 2014
Angiotensin-converting enzyme (ACE) and ACE2 are key regulators of the renin-angiotensin system, which has been shown to participate in a series of cardiovascular diseases. We hypothesized that dysregulated gene expression of ACE and ACE2 contribute to the formation of thoracic aortic dissection and aneurysm. We assessed ACE plasma concentration in ...
Keyte Anna L AL Brumley Neonatal Perinatal Research Institute, Department of Pediatrics, Duke University, Durham, North - - 2014
The cardiac neural crest cells (CNCCs) have played an important role in the evolution and development of the vertebrate cardiovascular system: from reinforcement of the developing aortic arch arteries early in vertebrate evolution, to later orchestration of aortic arch artery remodeling into the great arteries of the heart, and finally ...
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