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Steffensen Thora S TS 1Tampa General Hospital , Tampa, FL , - - 2014
Congenital coronary artery anomalies are rare. Pathologists are exposed to those in mainly two settings; in association with sudden death and usually extreme exercise in young adults, and in association with complex congenital heart disease in the pediatric and perinatal population. Pediatric pathologists, other pathologists and pathologists' assistants performing pediatric ...
Hammel James M JM Pediatric Cardiology, University of Nebraska Medical Center and Children's Hospital and Medical Center, Omaha, - - 2014
We present the anatomic constellation of mitral stenosis/aortic atresia variant of hypoplastic left heart syndrome, Ebstein's anomaly, and partial anomalous pulmonary venous return, an exceeding rare congenital heart defect. Prenatal echocardiography led to concern about the capacity of the right ventricle to increase cardiac output with lung expansion and pulmonary ...
Grzegorek Irmina I 1 Regional Specialized Hospital in Wroclaw, Research and Development Center , Wroclaw, Poland - - 2014
Abstract Twenty-six iliac artery segments were divided in two groups: atherosclerotic (A) and nonatherosclerotic (NA). Expression of LYVE-1, VEGF-C, VEGF-D, and CCR7 receptor were studied with immunohistochemistry (IHC) and Western blot (WB). IHC was performed on 26 samples of iliac arteries obtained from deceased 19 organ donors. The samples were ...
Channing Alexandra A The Fetal Heart Program at the Cardiac Center at the Children's, Hospital of Philadelphia, Philadelphia, PA, - - 2014
Aneurysm of the atrial septum (AAS) with excessive excursion of septum primum into the left atrium is an uncommon, relatively benign fetal condition associated with impediment to left ventricular (LV) filling and the appearance of a slender but apex-forming LV on fetal echocardiography. Impediment to filling can be severe creating ...
Tessitore Elena E Division of Cardiology, University Hospital of Geneva, Geneva, - - 2014
Quadricuspid aortic valve (QAV) is a rare congenital heart defect, often related to severe aortic regurgitation, and usually detected by echocardiography or at the time of aortic valve surgery. We report a case of an interesting and extremely rare variant of "false" QAV, detected preoperatively by transthoracic and transesophageal echocardiography, ...
Roden Anja C AC Department of Laboratory Medicine and Pathology, Mayo Clinic Rochester, MN, - - 2014
Pulmonary hypertension is a disease that is characterized by an increased pulmonary artery pressure and often results in right ventricular failure. Patients of any age might present with exertional dyspnea and fatigue, but clinical signs and symptoms can sometimes be difficult to recognize. Therefore, histopathology might become critical for the ...
Cataldo S S Adult Congenital Heart Disease Unit Bristol Heart Institute, Bristol, UK - - - 2014
There are a wide variety of coronary artery anomalies and disease in adults with congenital heart disease (CHD). In fact, the increasing burden of acquired coronary artery disease (CAD) has to be considered in addition to congenital abnormalities of the coronary arteries, isolated or associated to other congenital diseases. This ...
Soyer T T Faculty of Medicine, Department of Pediatric Surgery, Hacettepe University, Ankara, - - 2014
Prostaglandin E1 (PGE1) is widely used in ductus-dependant congenital heart disease to maintain the patency of ductus. Hypertrophic pyloric stenosis (HPS) due to gastric mucosal proliferation is a rare complication of prolonged PGE infusion. A male newborn who developed HPS during PGE1 infusion is presented to discuss the clinical features ...
Chen Heidi I - - 2014
Coronary arteries (CAs) stem from the aorta at 2 highly stereotyped locations, deviations from which can cause myocardial ischemia and death. CA stems form during embryogenesis when peritruncal blood vessels encircle the cardiac outflow tract and invade the aorta, but the underlying patterning mechanisms are poorly understood. Here, using murine ...
Lu Qixiu Q Department of Ultrasound, Shandong Jining No.1 People's Hospital, Jining, 272011, Shandong, China, - - 2014
The main objective of this study is to investigate the relationship between ascending aorta elasticity and the severity of coronary artery stenosis in essential hypertensive patients with coronary heart disease (CHD) using M-mode and tissue Doppler echocardiography. A total of 184 hypertensive patients with CHD were enrolled. Patients were divided ...
Zimmet Jeffrey J San Francisco VA Medical Center, 4150 Clement Street, Cardiology 111C, San Francisco, CA 94121 USA. - - 2014
This is the first reported case of partial aortic valve and annulus rupture during transcatheter aortic valve replacement, and its successful management through percutaneous means. It stresses the fact that even severe procedural complications can often be treated by a heart team endovascularly, without requiring sternotomy.
Delius Ralph E RE Department of Cardiovascular Surgery, Children's Hospital of Michigan, Detroit, Michigan. Electronic address: - - 2014
Three-patch repair of supravalvar aortic stenosis is a widely accepted surgical approach for this congenital heart lesion. We describe an unusual complication of this approach, which resulted in ischemia in the left anterior coronary artery distribution. Subtle oversizing of the left sinus of Valsalva patch led to kinking of the ...
Anderson R D RD Department of Cardiology, St Vincent's Hospital, Melbourne, Victoria, - - 2014
Interferon-alpha treatment is a rare cause of pulmonary arterial hypertension (PAH). We report a case of a 43-year-old man treated for chronic hepatitis C infection complicated by decompensated right heart failure diagnosed with PAH and external coronary artery compression secondary to a dilated pulmonary trunk. The novel complication of extrinsic ...
Salgado Rodrigo A RA From the Departments of Radiology (R.A.S., L.A., B.J.O.d.B., P.M.P.), Cardiology (B.S., P.L.V.H., C.V., J.B.), and Cardiothoracic Surgery (I.R.), Antwerp University Hospital, Wilrijkstraat 10, 2650 Edegem-Antwerp, Belgium; and Department of Radiology, Department of Medical Imaging, St Paul's Hospital, University of British Columbia, Vancouver, BC, Canada - - 2014
Aortic valve stenosis is the most common valvular heart disease in the Western world. When symptomatic, aortic valve stenosis is a debilitating disease with a dismal short-term prognosis, invariably leading to heart failure and death. Elective surgical valve replacement has traditionally been considered the standard of care for symptomatic aortic ...
Koo Hyun Jung HJ From the Department of Radiology and Research Institute of Radiology (H.J.K., D.H.Y., S.Y.O., J.W.K., T.H.L.), Division of Cardiology (D.H.K., J.K.S.), and Department of Cardiovascular Surgery (J.W.L., C.H.C.), Cardiac Imaging Center, Asan Medical Center, University of Ulsan College of Medicine, Asanbyeongwon-gil 86, Seoul 138-736, South - - 2014
Mitral valve prolapse (MVP), the most frequent cause of severe nonischemic mitral regurgitation, often warrants surgical or interventional valve repair. The severity of mitral regurgitation positively correlates with the development of heart failure and death. Even in patients who are asymptomatic, severe mitral regurgitation causes higher rates of death, heart ...
Alzahrani Ahmed M AM Congenital Heart Disease Section, Department of Medicine, Prince Sultan Military Medical City, Riyadh, Kingdom of Saudi - - 2014
A 38-year-old male was diagnosed with unrepaired ventricular septal defect associated with severe pulmonary arterial hypertension, cyanosis, and significant exercise intolerance. His echocardiogram showed right ventricular dysfunction and moderate pericardial effusion with no signs of cardiac tamponade. He was treated with an intensive course of inhaled iloprost and sildenafil. He ...
Poynter Jeffrey A JA Congenital Heart Surgeons Society Data Center, The Hospital for Sick Children, Toronto, Ontario, Canada Department of Surgery, Indiana University School of Medicine, Indianapolis, IN, - - 2014
Anomalous aortic origin of a coronary artery (AAOCA) encompasses a wide morphologic spectrum, which has impeded consensus regarding indications for the diverse repair strategies. We constructed a profile of current surgical techniques and explore their application to morphologic variants. Patients <30 years old (n = 113) with isolated AAOCA who ...
Kariyappa Mallesh M Department of Cardiology, Sri Jayadeva Institute of Cardiovascular Sciences and Research, Bengaluru, Karnataka, - - 2014
Congenital absence of the pulmonary valve is a rare congenital cardiac malformation, usually seen in association with tetralogy of Fallot. Patients generally present early in life with respiratory distress or recurrent respiratory tract infections, failure to thrive, cyanosis, infective endocarditis, or heart failure. Isolated absent pulmonary valve is quite rare ...
Tomanek Robert J RJ Department of Anatomy and Cell Biology, Carver College of Medicine, The University of Iowa, Iowa City, IA, - - 2014
Background: Coronary anomalies are frequently associated with congenital cardiac defects. Accordingly, we tested the hypothesis that the development of the tunica media of coronary arteries/arterioles is compromised in mice with cardiac defects of the outflow tract (persistent truncus arteriosus, double outlet right ventricle and transposition of the great arteries) by ...
Zamorano Jose L JL University Hospital Ramón y Cajal, Madrid, - - 2014
Mitral regurgitation is a common valvular heart disease and its prevalence is expected to increase with population ageing. Percutaneous techniques for the treatment of mitral regurgitation are emerging as an alternative therapeutic option. However, the mitral valve is a complex structure, and a comprehensive understanding of the anatomy of the ...
Mylotte Darren D Department of Interventional Cardiology, McGill University Health Centre, Montreal, QC, Canada Department of Cardiology, Galway University Hospital, Galway, - - 2014
A comprehensive description of transcatheter heart valve (THV) failure has not been performed. We undertook a systematic review to investigate the aetiology, diagnosis, management, and outcomes of THV failure. The systematic review was performed in accordance with the PRISMA guidelines using EMBASE, MEDLINE, and Scopus. Between December 2002 and March ...
Abou Zahr Riad R Department of Pediatrics, section of Pediatric Cardiology, Yale University School of Medicine, New Haven, CT, - - 2014
Trans-catheter balloon angioplasty is a well-established treatment modality for pulmonary artery stenosis in children with congenital heart disease. We report a case of an unusual complication where a fistula developed between the left pulmonary artery and the left atrium during balloon angioplasty in a patient with history of tetralogy of ...
Huang C C Department of Rheumatology, Peking Union Medical College Hospital, Key Laboratory of Rheumatology and Clinical Immunology, Ministry of Education, Beijing, - - 2014
A 35-year-old female patient was diagnosed with pulmonary arterial hypertension (PAH) by right heart catheterization (RHC) in the 3rd month of systemic lupus erythematosus (SLE) duration with high disease activity. Through methylprednisolone pulse therapy, she got total recovery from PAH proven by repeat catheterization and follow-ups. This is the first ...
Loukas Marios M Department of Anatomical Sciences, St. George's University, Grenada, West Indies; Department of Anatomy, Varmia and Mazuria Medical School, Olsztyn, - - 2014
Coronary arteries have been extensively described and recognized by gross anatomic studies. However, in the clinical setting, the recognition of the conal artery is essential during coronary angiography, as well as certain congenital heart conditions such as tetralogy of Fallot. In order to provide a complete anatomic and physiologic correlation ...
Morsi Yosry S YS Biomechanics and Tissue Engineering Group, Faculty of Science, Engineering and Technology, Swinburne University of Technology, Melbourne - - - 2014
The occurrence of dysfunctional aortic valves is increasing every year, and current replacement heart valves, although having been shown to be clinically successful, are only short-term solutions and suffer from many agonizing long-term drawbacks. The tissue engineering of heart valves is recognized as one of the most promising answers for ...
Tanemoto Kazuo K Department of Cardiovascular Surgery, Kawasaki Medical School, 577 Matsushima, Kurashiki City, Okayama, 701-0192, Japan, - - 2014
For successful repeated valve replacement surgery, it is essential issue that the preoperative evaluation includes an assessment of the previous operation record, computed tomography (CT: including 3D-CT), ultrasound cardiography, coronary artery angiography, and so on. Although it is especially needed for repeated valve replacement surgery, setting up of the external defibrillation ...
D'Alto Michele M Department of Cardiology, Second University of Naples - Monaldi Hospital, Naples, - - 2014
Echocardiography is a key screening tool in the diagnostic algorithm of pulmonary arterial hypertension (PAH). It provides an estimate of right ventricular function and pulmonary artery pressure, either at rest or during exercise, and is useful in ruling out secondary causes of pulmonary hypertension (PH) such as left heart disease ...
Godinho Ana Rita AR Serviço de Cardiologia, Hospital de São João, Porto, Portugal. Electronic address: - - 2014
The authors present the case of a 68-year-old man with predominantly right heart failure in the context of severe aortic stenosis associated with pulmonary hypertension. Anemia was diagnosed which, after endoscopic study, was considered to be secondary to angiodysplasia and a diagnosis of Heyde syndrome was made. After valve replacement ...
Li Yang Y Department of Cardiovascular Surgery, West China Hospital, Sichuan University, Chengdu, Sichuan, People's Republic of - - 2014
Angiotensin-converting enzyme (ACE) and ACE2 are key regulators of the renin-angiotensin system, which has been shown to participate in a series of cardiovascular diseases. We hypothesized that dysregulated gene expression of ACE and ACE2 contribute to the formation of thoracic aortic dissection and aneurysm. We assessed ACE plasma concentration in ...
Keyte Anna L AL Brumley Neonatal Perinatal Research Institute, Department of Pediatrics, Duke University, Durham, North - - 2014
The cardiac neural crest cells (CNCCs) have played an important role in the evolution and development of the vertebrate cardiovascular system: from reinforcement of the developing aortic arch arteries early in vertebrate evolution, to later orchestration of aortic arch artery remodeling into the great arteries of the heart, and finally ...
Cozzi Corin T CT 1Division of Neonatology,Nationwide Children's Hospital,Columbus,Ohio,United States of - - 2014
Background: Altered mesenteric perfusion may be a contributor to the development of necrotising enterocolitis in patients with hypoplastic left heart syndrome. The goal of this study was to document mesenteric flow patterns in patients with hypoplastic left heart syndrome pre- and post-hybrid procedure. Methods: A prospective study on all patients ...
Ruttkay Tamas T Department of Cardiac Surgery, Sana Cardiac Surgery Stuttgart GmbH, Stuttgart, - - 2014
Background An increasing number of experimental beating heart animal studies describe simple transapical mitral valve repairs based on the direct endoscopic visualization of the left ventricle. The aim of our human cadaveric study was to develop a method for more complex transapical endoscopic procedures by on-pump heart operations. Materials and Methods After ...
Serio Paola P Respiratory Endoscopy Unit, Department of Paediatric Anesthesia and Intensive Care, Meyer Children Hospital, Florence, Italy. Electronic address: - - 2014
Anomalous left coronary artery from pulmonary artery (ALCAPA) is a rare congenital anomaly in which left coronary artery arises from the pulmonary artery resulting in progressive myocardial ischemia and dysfunction of the left ventricle. We report a case of ALCAPA with severe cardiac and respiratory failure and huge heart dilation ...
Berthelot E E Department of cardiology, Bicetre Hospital, AP-HP, Le Kremlin-Bicêtre, - - 2014
Coupled arterial and left ventricular properties are poorly documented in acute heart failure. The aim of this prospective non invasive study was to document early changes in ventricular-arterial coupling in patients with acutely decompensated HF (ADHF). We studied 19 patients hospitalized for ADHF (age 62±15 years, NYHA class 3 or ...
Mackman Chad A CA Division of Cardiology, Department of Pediatrics, Medical College of Wisconsin, Milwaukee, WI, USA, - - 2014
Cor triatriatum dexter is a rare congenital heart defect that can lead to cyanosis in a newborn with an otherwise normal exam. The initial evaluation of these patients typically focuses on searching for a pulmonary etiology for arterial desaturation, which often leads to a negative work up. When cardiac evaluation ...
Emren Zeynep - - 2014
ObjectivesThe aim of the present study was to retrospectively evaluate the prevalence of concurrent coronary artery disease in patients who underwent surgery due to severe valvular heart disease. The study also investigated the association of coronary artery disease with the type of valvular heart disease.Materials and methodsA total of 241 ...
Guo Xiaojuan X Department of Radiology, Beijing Chao-Yang Hospital, Capital Medical University, Beijing, China. - - 2014
We aimed to determine the correlation between flow characteristics of the proximal pulmonary arteries and vena cava obtained by 3.0 T phase-contrast magnetic resonance imaging (MRI) and hemodynamic characteristics by right heart catheterization in patients with chronic thromboembolic pulmonary hypertension. Twenty consecutive patients with chronic thromboembolic pulmonary hypertension and 20 ...
Kato Takayoshi T Department of Cardiovascular Surgery, Gifu Heart Center, Gifu, Japan - - 2014
Aneurysm of the sinus of Valsalva is an uncommon entity and especially rare when it dissects into the intraventricular septum. This uncommon clinical manifestation often takes a drastic clinical course with life-threatening arrhythmia, coronary ischemia, rupture, and heart failure. We present the case of a 36-year-old man with an aneurysm ...
Furutachi Akira A Department of Thoracic and Cardiovascular Surgery, National Hospital Organization Ureshino Medical Center, Saga, Japan. Electronic address: - - 2014
Patients with thoracoabdominal aortic aneurysms (TAAA) often have severe ischemic heart disease. The determination of which condition to treat first is based on disease severity, but in some cases the conditions are equally severe. A 78-year-old woman received a diagnosis of a 59-mm TAAA and coronary artery stenosis. We performed ...
Dai Jian J Department of Cardiology, Shu Guang Hospital Bao Shan Branch, Shanghai University of Traditional Chinese Medicine, Shanghai, - - 2014
A single coronary artery (SCA) arising from the sinus of Valsalva and supplying the entire heart is a rare congenital anomaly. According to the modified Lipton's classification, R-1 is by far the most rare subtype of SCA, with an incidence of 0.0008% in patients undergoing coronary angiography. We present a ...
Liao Ying Y Department of Cardiology, Longyan First Hospital, Fujian Medical University, Longyan 364000, - - 2014
A 22-year-old young man with a history of idiopathic dilated cardiomyopathy (IDC) was admitted to our hospital due to difficult-to-control heart failure. A thoracic X-ray showed multiple nodules at the both pulmonary hilus and upper lobe of the right lung. Computed tomography (CT) angiography of the thorax confirmed arteriovenous malformation ...
Moon Sung Woo SW Division of Cardiology, Severance Cardiovascular Hospital, Yonsei University College of Medicine, Seoul, - - 2014
Transcatheter aortic valve implantation (TAVI) has shown favorable outcomes in patients with severe symptomatic aortic valve stenosis who are at high surgical risk or are unsuitable candidates for open heart surgery. However, concerns exist over treating patients who have previously undergone mitral valve surgery due to the potential interference between ...
Kang Young Ran YR Department of Internal Medicine, Gyeongsang National University Hospital, Gyeongsang National University School of Medicine, Jinju, - - 2014
Autosomal dominant polycystic kidney disease (ADPKD) is a systemic disorder associated with various extrarenal complications. The major cardiovascular complications of ADPKD include valvulopathies and vascular ectasia. A 64-year-old man who was diagnosed with ADPKD seven years previously was admitted to our hospital for heart failure. Pelvic computed tomography revealed multiple ...
Gibyeli Genek Dilek D Department of Nephrology, Dokuz Eylul University School of Medicine, Izmir, - - 2014
Primary failure, early thrombosis, and inadequate maturation are the main complications encountered in arteriovenous fistulas. Doppler ultrasonographic assessment of flow-mediated dilatation (FMD) is currently used for the early diagnosis of atherosclerosis. Clinical experience in the use of FMD for preoperative assessment of vasculature is rather limited; therefore, we sought to ...
Watanabe Taiju T Department of Cardiovascular Surgery, Tokyo Medical and Dental University Graduate School of Medical and Dental Sciences, 1-5-45 Yushima, Bunkyo-ku, Tokyo, 113-8519, - - 2014
Mitral valve repair is the preferred surgical treatment for mitral regurgitation. Cardiac surgeons must increasingly pursue high-quality mitral valve repair, which ensures excellent long-term outcomes. Intraoperative assessment of a competency of the repaired mitral valve before closure of the atrium is an important step in accomplishing successful mitral valve repair. ...
Hata Toshiyuki T Department of Perinatology and Gynecology, Kagawa University Graduate School of Medicine, Miki, Japan. Electronic address: - - 2014
The investigators present their experience with normal fetal cardiac structures and congenital heart anomalies reconstructed using 4-dimensional color Doppler with glass-body rendering mode and spatiotemporal image correlation. Two normal fetuses and 6 fetuses with congenital heart anomalies (1 case each of ventricular septal defect, Ebstein's anomaly, hypoplastic left heart syndrome, and ductus ...
Pellegrino Vincent V aDepartment of Intensive Care and Hyperbaric Medicine, The Alfred Hospital bDivision of Clinical Sciences and Department of Surgery, Central Clinical School, Monash University cSchool of Public Health, Department of Epidemiology and Preventive Medicine, Monash University dAustralian and New Zealand Intensive Care Society Research Centre, Melbourne, - - 2014
To examine the utility and technical challenges of applying veno-arterial extracorporeal membrane oxygenation for acute cardiovascular failure in adults with acute and chronic causes of heart failure. The role of mechanical circulatory support in acute cardiovascular continues to evolve as technology and clinical experience develop. There is increasing interest in ...
Lam John C JC John C Lam, Michael Giuffre, Kimberley A Myers, Department of Pediatrics, University of Calgary, Alberta Children's Hospital, Calgary, Alberta T3B 6A8, - - 2014
Anomalous left coronary artery from the pulmonary artery (ALCAPA) is most commonly diagnosed within the first year of life with congestive heart failure symptomatology reflecting left ventricle (LV) dysfunction. The late diagnosis of ALCAPA is presented in a 5-year-old without significant LV dysfunction, mild LV dilatation and only mild mitral ...
Matsushita Kunihiro K Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland; - - 2014
Whether inclusion of the coronary artery calcium score improves cardiovascular risk prediction in individuals with CKD, a population with unique calcium-phosphate homeostasis, is unknown. Among 6553 participants ages 45-84 years without prior cardiovascular disease in the Multi-Ethnic Study of Atherosclerosis, coronary artery calcium score was assessed for cardiovascular risk prediction ...
Nagaoka Ryo R Department of Biomedical Imaging, Graduate School of Biomedical Engineering, Tohoku University, 6-6-05 Aramaki Aza Aoba, Aobaku, Sendai 980-8579, Japan. Electronic address: - - 2014
Pulse-wave velocity (PWV) is an important index for diagnosing cardiovascular diseases. The pulse wave is volumetric change induced by heartbeat or inflowing blood, and significantly depends on the propagating path and stiffness of the artery. In this study, PWV of the propagating wave was visualized using spatial compound imaging with ...
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