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Ten Kate Gerrit L - - 2012
B-mode and Doppler ultrasound are commonly used for the evaluation of atherosclerosis in the carotid arteries. Recently, contrast-enhanced ultrasound (CEUS) has been introduced as a technique to improve the detection of carotid atherosclerosis and evaluate the presence of intraplaque neovascularization, which is considered a marker of plaque vulnerability. The present ...
Kunte Hagen - - 2012
A 62-year-old man was admitted after recurrent transient left-sided weakness and sensory loss. Ultrasound (US) examination revealed a 70% narrowing of the right proximal internal carotid artery (ICA). Contrast-enhanced US suggested plaque neovascularization (figure, A). Carotid endarterectomy of the right ICA was performed. Immunohistochemistry of the specimen showed, corresponding to ...
Kuroyanagi Satoshi - - 2012
This report describes the complementary use of transit-time flow measurement (TTFM) and intraoperative fluorescence imaging (IFI) during off-pump coronary artery bypass grafting (OPCAB) and compares their results with those of subsequent coronary angiography. The subjects were 159 OPCAB patients, with a total of 435 grafts at a single center between ...
Molthen Robert C RC Division of Pulmonary and Critical Care, Department of Medicine, Medical College of Wisconsin, Milwaukee, Wisconsin 53226, USA. - - 2012
A single dose of 10 Gy radiation to the thorax of rats results in decreased total lung angiotensin-converting enzyme (ACE) activity, pulmonary artery distensibility and distal vascular density while increasing pulmonary vascular resistance (PVR) at 2 months post-exposure. In this study, we evaluate the potential of a renin-angiotensin system (RAS) ...
Ruzevick Jacob - - 2012
BACKGROUND:: Inflammation and macrophages in particular are believed to play a role in aneurysm formation. The haptoglobin (Hp) 2-2 genotype is associated with a pro-inflammatory state. OBJECTIVE:: To investigate the role of inflammation in the formation of aneurysms using a murine model of aneurysm formation in transgenic, pro-inflammatory, Hp2-2 mice ...
Briet Marie - - 2012
CKD (chronic kidney disease) is a severe and complex disease with a very high prevalence of CV (cardiovascular) complications. CKD patients are exposed to haemodynamic disturbances in addition to severe metabolic abnormalities that lead to a specific form of arterial remodelling, which contributes to the development of CV disease. Arterial ...
Chan Melissa V - - 2012
Pre-menopausal females have a lower incidence of cardiovascular disease compared with age-matched males, implying differences in the mechanisms and pathways regulating vasoactivity. In small arteries, myogenic tone (constriction in response to raised intraluminal pressure) is a major determinant of vascular resistance. Endothelium-derived dilators, particularly NO, tonically moderate myogenic tone and, ...
Swift Andrew J AJ Unit of Academic Radiology, University of Sheffield, Sheffield, UK. - - 2012
The aim of this study was to evaluate the clinical use of magnetic resonance imaging measurements related to pulmonary artery stiffness in the evaluation of pulmonary hypertension (PH). A total of 134 patients with suspected PH underwent right heart catheterization (RHC) and magnetic resonance imaging on a 1.5-T scanner within ...
Caputo Salvatore - - 2012
In a 28-year-old female, with symptoms and clinical signs of right heart failure, transthoracic echocardiography and abdominal, three-dimensional, contrast-enhanced, computed tomography revealed a rare type of portopulmonary hypertension. She had a severe pulmonary artery hypertension associated with an unusual (and, to our knowledge, not previously described) pattern of Abernethy malformation, ...
Su Junjing - - 2012
Combretastatin-A4-phosphate (CA4P/CA4), an anti-cancer drug, induces tumour hypoxia by destabilizing the cytoskeleton in tumour endothelial cells. Hypertensive side effects have been observed. We hypothesized that CA4P/CA4 lead to endothelial dysfunction followed by increased vasoconstriction. Mesenteric small arteries and femoral arteries isolated from male Wistar rats were mounted in microvascular myographs ...
Yan Yan - - 2012
The objective of our study was to assess outcomes after evaluation of immature hemodialysis arteriovenous fistulas (AVFs) via 3-French brachial artery access and to identify the incidence of arterial and venous puncture site spasm. One hundred twenty-three outpatients (82 men, 41 women; mean age, 58 years; age range, 20-90 years) ...
Zayed Reham - - 2012
Sildenafilcitrate (SILD) orodispersable sublingual tablets (ODSTs) have been developed using two comparative techniques for improving their oral disintegration, dissolution and bioavailability in order to manage acute attacks of pulmonary arterial hypertension (PAH). The techniques employed were direct compression of SILD-poloxamer 188 solid dispersions (SDs) and freeze drying using various excipients. ...
Durand M - - 2012
A 24-year-old female presented to her general practitioner with shortness of breath. She was referred for an echocardiogram, which demonstrated features suggestive of a right coronary artery fistula, and referred to our institute. We performed a contrast-enhanced, prospectively triggered cardiac CT angiogram, which demonstrated the primary and secondary features of ...
Antoniou G - - 2012
Endovascular repair of popliteal artery aneurysms is an emerging treatment in high risk surgical patients. The location in a functionally demanding anatomical area creates limitations in terms of endograft patency. Technological advancements have been conscripted in an effort to circumvent such constraints. The multilayer stent technology effects through haemodynamic modulation. ...
Sawazaki Masaru - - 2012
Typically, a sinus of Valsalva aneurysm with severe aortic incompetence is repaired with patch closure and aortic valve replacement. Here, we describe a very rare case of a giant nonruptured right Valsalva aneurysm, combined with severe aortic incompetence, treated with a valve-sparing aortic root replacement. During surgery we noted that ...
Garg Pankaj - - 2012
In the present report, we discuss a patient who developed persistent hypoxemia after an attempt at Fontan completion failed. As a bail-out procedure, a left common carotid artery to left internal jugular vein shunt was constructed, after which the hypoxemia was relieved.
Kalfa David - - 2012
Invasive pulmonary aspergillosis is a life-threatening infectious complication. The optimal management is still controversial, especially in cases of upper lobe lesions involving vascular structures. We report the case of a 24-year-old man with a granulocytic sarcoma of the left pulmonary apex, complicated by invasive pulmonary aspergillosis and false aneurysm of ...
Rademakers L M - - 2012
We describe a case of critical hand ischaemia after transradial cardiac catheterisation. The patient presented with hand ischaemia 5 days after transradial coronary angiography. Urgent angiography demonstrated radial artery occlusion with embolisation to the palmar arch and digital arteries. The ischaemia was refractory to an extensive thrombolytic regimen, and subsequently, the ...
Goltz J - - 2012
Acute thromboembolic occlusion of the superior mesenteric artery is a rare and often fatal condition in which surgery represents the golden standard in therapy. We present a case in which a patient was treated with covered stent implantation for acute bleeding from the superior mesenteric artery following pancreatic resection, radiation, ...
Pop Daniel - - 2012
The presence of an aberrant right subclavian artery represents a potentially risky situation when high mediastinal surgery is planned. We report a case of a patient needing transhiatal esophagectomy for cancer; the presence of the abnormal anatomic arterial situation complicated the postoperative course, when a vascular- digestive fistula appears. We ...
Smith Craig R - - 2012
Penetrating ascending aortic ulcers are rarely encountered, yet they present significant risk of hemorrhage and aortic dissection. Expedient recognition and repair is of vital importance. The current management of penetrating ulcer of the ascending aorta includes replacement of the ascending aorta with a prosthetic graft. We describe our technique of ...
Krishnan Anant S - - 2012
The pulmonary artery is affected by a multitude of conditions that can be congenital or acquired. These disorders may be detected incidentally, or the clinical features of the different conditions may overlap. This pictorial review illustrates the imaging findings of some of the main conditions that affect the pulmonary artery ...
Kroigaard Christel - - 2012
Small (K(Ca) 2) and intermediate (K(Ca) 3.1) conductance calcium-activated potassium channels (K(Ca) ) may contribute to both epithelium- and endothelium-dependent relaxations, but this has not been established in human pulmonary arteries and bronchioles. Therefore, we investigated the expression of K(Ca) 2.3 and K(Ca) 3.1 channels, and hypothesized that activation of ...
Paffett Michael L ML Department of Pharmaceutical Sciences, MSC09 5360, College of Pharmacy, University of New Mexico, Albuquerque, NM 87131-0001, USA. - - 2012
Atrophic signaling elements of the ubiquitin-proteasome system (UPS) are involved in skeletal muscle wasting as well as pressure overload models of heart failure. In our prior experiments, we demonstrated a transcriptional downregulation of atrophy-inducing vascular E3 ubiquitin ligases in a toxic model of pulmonary hypertension where pulmonary artery and right ...
Toutouzas Konstantinos - - 2012
Aims: Plaque rupture and subsequent thrombosis is known to be the most important pathology leading to acute coronary syndrome (ACS). We investigated by optical coherence tomography (OCT) whether in ACS there is an association of the location of the culprit plaque in the coronary tree with plaque rupture and/or thin ...
Rishi Anupam - - 2012
BACKGROUND: Arterial thromboses following cisplatin-based chemotherapy in head and neck cancers are extremely rare and devastating complication. METHODS AND RESULTS: A 54-year-old male smoker had an acute history of left lower limb pain and calf claudication 3 days following the first cycle of cisplatin-based chemotherapy given concurrently with radiotherapy for ...
Morrison Keith - - 2012
{4-[(5,6-Diphenylpyrazin-2-yl)(isopropyl)amino]butoxy}acetic acid (ACT-333679) is the main metabolite of the selective prostacyclin (PGI(2)) receptor (IP receptor) agonist selexipag. The goal of this study was to determine the influence of IP receptor selectivity on the vasorelaxant efficacy of ACT-333679 and the PGI(2) analog treprostinil in pulmonary artery under conditions associated with pulmonary ...
Oka F - - 2012
SUMMARY:CEA contralateral to an ICA occlusion is considered a surgical risk, and CAS may be an alternative for these patients. Our goal was to examine whether CAS improves cerebral hemodynamics on the treated side and on the side of the ICA occlusion, on the basis of measurement of CBF and ...
Wang Yibo - - 2012
VKORC1 genetic polymorphisms affect warfarin dose response, aortic calcification, and the susceptibility of coronary artery disease as shown in our previous study. Little is known regarding the association of VKORC1 polymorphisms with coronary artery calcification (CAC) and the role of CAC in the association with coronary artery disease (CAD). Due ...
Kim Hyun Gyung - - 2012
Vascular calcification of the coronary arteries or aorta is an independent risk factor for cardiovascular outcome, but clinical significance of arterial micro-calcification (AMC) of vascular access is unclear in hemodialysis (HD) patients. Sixty-five patients awaiting vascular access operation were enrolled. We compared surrogate markers of cardiovascular morbidity such as aortic ...
Takami Toshihiro - - 2012
ABSTRACT: Study Design. This is technical case reports of direct surgery for spinal arteriovenous fistulas (AVFs) of the filum terminale.Objective. We present two cases of spinal AVFs of the filum terminale directly fed by the anterior spinal artery that were successfully obliterated with intraoperative image guidance such as digital subtraction ...
Santis Francesco De - - 2012
Cervicocephalic artery dissections occurring during dental care have exceptionally been reported. We describe a case of internal carotid artery dissection, presenting as hypoglossal nerve palsy, occurring immediately after difficult inferior alveolar nerve anesthetic block for third inferior molar dental care. Carotid dissection was successfully treated with anticoagulation therapy while hypoglossal ...
Steigerwald Kristin - - 2012
OBJECTIVES:: Catheter-based renal artery denervation has been successfully introduced as alternative treatment for patients suffering from drug-resistant essential hypertension. However, the local morphological changes within the vessel wall accompanying this technique remain elusive and we sought to characterize these by utilizing the simplicity radiofrequency catheter approach. METHODS:: Following treatment of ...
Willson Thomas D - - 2012
Hepatic artery aneurysms are the second most common visceral aneurysm but are still relatively uncommon. Over the last century, methods for treating these lesions have evolved substantially. The presented case covers the presentation, diagnosis, and treatment of a 65-year-old woman with an aneurysm of the intrahepatic portion of the hepatic ...
Funaki Soichiro - - 2012
Video-assisted thoracic surgery is useful during a typical lobectomy procedure, though challenging in complicated cases. We report successful video-assisted thoracic surgery lobectomy procedures performed after coronary artery bypass grafting in two lung cancer patients, with severe adhesion of lung parenchyma to grafts of the internal thoracic artery. We avoided dissection ...
Helgadottir Anna A Population Genomics, deCODE Genetics, Reykjavik, Iceland. - - 2012
The purpose of this study is investigate the effects of variants in the apolipoprotein(a) gene (LPA) on vascular diseases with different atherosclerotic and thrombotic components. It is unclear whether the LPA variants rs10455872 and rs3798220, which correlate with lipoprotein(a) levels and coronary artery disease (CAD), confer susceptibility predominantly via atherosclerosis ...
Wang Shuang - - 2012
PURPOSE: To describe the 5-year incidence of retinal microvascular abnormalities and analyze their associations with arterial hypertension in nondiabetic elderly Chinese subjects in urban and rural Beijing in a follow-up of the original Beijing Eye Study 2001. DESIGN: Population-based study. PARTICIPANTS: The Beijing Eye Study 2006 included 3251 subjects who ...
Boni Lorenzo - - 2012
OBJECTIVES: This study investigated the time-dependent remodeling and growth potential of porcine small intestine submucosa as a biomaterial for the reconstruction of pulmonary arteries in a lamb model. METHODS: Left pulmonary arteries were partially replaced with small intestine submucosal biomaterial in 6 lambs. Two animals each were humanely killed at ...
Kaneko Tsuyoshi - - 2012
OBJECTIVE: Management of a patent left internal thoracic artery graft during reoperation is controversial. The "no-dissection" technique avoids dissection and clamping of the left internal thoracic artery graft, and myocardial protection is achieved using adjunctive systemic hypothermia and hyperkalemia. We compared the postoperative outcomes after isolated reoperative aortic valve replacement ...
Misuraca Leonardo - - 2012
We present the case of a 67 year-old patient that presented to our institution with acute and severe chest pain. Optical coherence tomography high-resolution images of the coronary lumen, allowed us to confirm diagnosis of spontaneous coronary artery dissection, guide treatment, and verify the results of our intervention.
Liu Ming - - 2012
Epidemiological data have shown that methamphetamine (MA) abuse significantly increases the risk of developing pulmonary arterial hypertension (PAH). To investigate whether MA could induce PAH and its possible mechanism, rats were exposed daily to MA for 5 weeks in the absence or presence of fluoxetine. The results showed that the ...
Fracassi Francesco - - 2012
Coronary aneurysmatic dilatation may be localized to a segment or may involve multiple segments. We herein report a case of a diffuse aneurysmatic dilatation of the right coronary artery.
Rios Rodrigo - - 2012
The arterial switch operation is the surgical correction of choice for patients born with d-transposition of the great arteries (d-TGA) and an intact ventricular septum. However, prematurity and very low birth weight present both technical and physiologic challenges to this approach. Furthermore, in the setting of d-TGA and an intact ...
Buchanan Gill Louise - - 2012
Percutaneous balloon aortic valvuloplasty is used in high-risk patients with significant aortic stenosis, either as palliation or as a bridge to more definitive treatment. We report the case of a high-risk patient, a man aged 71 years and with multiple comorbidities, undergoing this procedure. Following the procedure, he was given ...
Santos-Franco J A - - 2012
Summary. Juvenile nasopharyngeal angiofibroma (JNA) is a rare histologically benign tumor, highly vascularized, with usually aggressive behavior, and can extend from the nasal cavity to neighboring structures. We present the case of a 14-year-old male harboring a JNA, presenting with an active severe and persistent epistaxis. Two previous surgical attempts ...
Corban Michel T - - 2012
We present a case of a 43-year-old woman with history of hybrid coronary revascularization [endoscopic atraumatic coronary artery bypass (ACAB)] of left internal mammary artery (LIMA) to the left anterior descending artery (LAD) and stent implantation in right coronary artery (RCA), who presented six years later with recurrent atypical angina. ...
Sadek Mikel - - 2012
A 72-year-old woman with end-stage renal disease was admitted with right upper quadrant pain, hypotension, an elevated bilirubin, and leukocytosis. A computed tomography scan showed a dilated common bile duct and an associated 4.5 cm gastroduodenal artery pseudoaneurysm. The pseudoaneurysm was coil embolized successfully while maintaining dual access from the ...
Minai Omar A - - 2012
OBJECTIVES: Pulmonary hypertension (PH) has been associated with decreased functional capacity in patients with advanced idiopathic pulmonary fibrosis (IPF). We aimed to evaluate the true impact of altered pulmonary hemodynamics on functional capacity in a cohort of patients with IPF. METHODS: Between January 1990 and December 2007, 124 patients [73M/51F; ...
Shinohara Y - - 2012
BACKGROUND AND PURPOSE:Flat panel detector-based CBCT can provide CT-like images of the brain without transferring patients from the angiography suite to a conventional CT facility. Conventional brain CT after uneventful endovascular treatment sometimes shows focal subarachnoid hyperattenuation with contrast leakage, mimicking SAH. Differentiating this finding from SAH is important for ...
Chen Fengshi - - 2012
In living-donor lobar lung transplantation (LDLLT), donor surgeries are conducted in ways that ensure proper dissections for both donors and recipients. We report a case of LDLLT, in which pulmonary arterioplasties with autopericardial patch were performed on both a donor and a recipient. Since excision of the lingular branch of ...
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