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Davies Michael H MH Department of Pediatrics, Oregon Health & Science University, Portland, Oregon, - - 2010
EphrinB2 ligands and EphB4 receptors are expressed on endothelial cells (EC) of arteries and veins, respectively, and are essential for vascular development. To understand how these molecules regulate retinal neovascularization (NV), we evaluated their expression in a model of oxygen-induced retinopathy (OIR). EphrinB2 and EphB4 were expressed on arterial and ...
Hwang Gyojun - - 2010
Central retinal artery occlusion (CRAO) causes severe visual loss in affected eye and vision does not recover in more than 90% of the patients. It is believed that it occurs by occlusion of the central retinal artery with small emboli from atherosclerotic plaque of internal cerebral artery. Retina is a ...
Parc C - - 2010
The G20210A mutation in the prothrombin gene is an established risk factor for venous thrombosis. There is controversy as to the role played by this mutation in arterial thrombotic disease. We present the case of a 56-year-old man who presented with a central retinal artery occlusion of the left eye. ...
Mannino Giuseppe - - 2010
PURPOSE: Branch retinal artery occlusion caused by calcific embolization secondary to calcific aortic valvulopathy. METHODS: A 45-year-old woman came to our attention complaining a sudden painless loss of her peripheral superior visual field. Best visual acuity was 20/20. Fundus examination revealed the presence of a retinal arterial embolic occlusion of ...
Weiss Jeffrey N - - 2010
Five patients with a one- to 12-day history of symptoms secondary to retinal artery occlusion (RAO) were treated with hyperbaric oxygen therapy (HBO2) for one hour at 1.5 ATA. Four patients had been diagnosed with branch retinal artery occlusion (BRAO) and one patient with a cilioretinal artery occlusion. The three ...
Theoulakis P E - - 2010
BACKGROUND: We describe the clinical findings and course of cilioretinal artery occlusion (CAO) combined with central retinal vein occlusion (CRVO) in two patients and present a review of the relevant literature. HISTORY AND SIGNS: Case 1: An otherwise healthy 24-year-old woman presented to the emergency unit with a painless visual ...
Ghazi Nicola G - - 2010
PURPOSE: The purpose of this study was to report differentiating optical coherence tomography (OCT) findings between postacute retinal arterial occlusion (PARAO) and nonacute optic neuropathy (NAON). METHODS: A retrospective observational comparative study included 17 eyes with postacute permanent retinal arterial occlusion and 32 eyes with NAON whose assessment included a ...
Gehlert S - - 2010
Purpose of these study was the evaluation of a new method for the measurement of haemoglobin oxygenation in retinal vessels. Patients with branch retinal artery occlusion have been measured before and after a rheological therapy. The haemoglobin oxygenation in retinal vessels was measured by the "oxygen module" (Imedos GmbH, Jena, ...
Furino Claudio - - 2010
Intravitreal bevacizumab for macular edema secondary to central retinal vein occlusion may induce resolution of macular edema. However, the possibility of a rebound macular edema thicker than at the initial presentation after intravitreal bevacizumab injections has been reported. A case of dramatic deterioration of central retinal vein condition with hemorrhagic ...
Viana Luiz Carlos - - 2011
The actual effect of steroid hormones on cerebral microcirculation is still controversial. Therefore, the aim of our study was to investigate vascular flow variations in the central retinal artery that may exist during the ovulatory menstrual cycle. A total of 34 healthy women were included in this observational, longitudinal, and ...
Parcero Cíntia Maria Felix Medrado - - 2010
to report a case of branch retinal artery occlusion in the acute phase, using optical coherence tomography to evaluate the morphologic changes. A 27 year-old man had a sudden superior scotoma in the right eye, with fundus examination compatible with inferior temporal branch retinal artery obstruction. The optical coherence tomography ...
Das Debabrata - - 2010
Takayasu's arteritis is a chronic inflammatory disease of the large and medium-sized arteries. It commonly involves the aorta with its branches and the pulmonary arteries. The retinal hemodynamics suggest that the carotid artery involvement causes diminished retinal blood flow. This is the pathogenetic mechanism of Takayasu's retinopathy with characteristic features ...
Chen Kinon - - 2010
We studied contribution of blood vessels to the mechanical properties of retina. Previous studies revealed anisotropic and inhomogeneous retinal mechanical characteristics. To examine different vessel types and sizes, 3 strips of retinal samples were dissected in each of 5 pig eyes. One strip contained the superior-temporal vein in the axial ...
Parker J A T C - - 2010
We here present the case of a rarely seen anomalous origin and retropulmonary course of the left circumflex artery from the proximal right coronary artery. The patient suffered from coronary ischemia due to stenotic lesions both in the aberrant circumflex coronary artery and in the first and second diagonal branches. ...
Camuglia Jayne E - - 2010
The vascular complications of herpes zoster are well recognised, however, there are few reports of central retinal artery occlusion. Central retinal artery occlusion following herpes zoster ophthalmicus is poorly recognised. This is likely due to the difficulties in obtaining tissue for histopathology to establish causality. We report a case of ...
Masugata Hisashi - - 2010
Scheie's classification regarding hypertensive and atherosclerotic lesions in retinal arteries is generally used to assess the severity of hypertensive retinopathy and the risks of cardiovascular events in hypertensive patients. However, the differences between these two types of retinal artery lesions have not been fully examined. Both arterial stiffness and aortic ...
Chu Edward R - - 2010
Ophthalmic involvement in giant cell arteritis can manifest in a number of ways. Central retinal artery occlusion is one of the common causes of visual loss in giant cell arteritis. On the contrary, branch retinal vein occlusion is rarely associated with the latter. We report an 89-year-old lady with acute ...
Mathew Raeba - - 2010
The purpose of this study is to illustrate the fundus autofluorescence and high-definition optical coherence tomography (HD-OCT) features of acute and long-standing retinal artery occlusions. Retrospective case series. Patients with acute and chronic retinal and cilioretinal artery occlusions are included in this series. A detailed clinical examination, color fundus photographs, ...
Karia Niral - - 2010
This paper reviews the current thinking about retinal vein occlusion. It gives an overview of its pathophysiology and discusses the evidence behind the various established and emerging treatment paradigms.
Murthy R K - - 2010
Branch retinal artery occlusions (BRAO) are characterized histopathologically by inner retinal edema initially and atrophy in the presence of persistent ischemia. The duration of ischemia leading to irreversible atrophic retinal changes is not clear. Spectral-domain optical coherence tomography (SD-OCT) provides non-invasive detailed in-vivo histological changes in the retina. In this ...
Ayati Maryam - - 2010
We present two cases of mitral valve lesions that manifested with unilateral blindness caused by central retinal artery occlusion (CRAO): Case 1. A 68-year-old woman was admitted to our clinic for sudden blindness. Retinal artery angiogram showed CRAO. Transthoracic and transesophageal echocardiography (TEE) documented a mass attached to the ventricular ...
McGuire Ciara - - 2009
Visual loss is a devastating complication of non-ophthalmic surgery. It is documented following cardiac, spinal, and transplant surgery. Patients with carotid artery occlusion are at increased risk for ocular ischaemia. Pre-operative assessment as well as early diagnosis and treatment is essential in cases of high-risk patients. We discuss the case ...
Asok T - - 2009
A 14 year old boy underwent a 7 hour long spinal surgery for scoliosis in the prone position. In the immediate postoperative period, he developed right proptosis, periorbital swelling, chemosis and total ophthalmoplegia. The vision in his right eye was only counting fingers and the intraocular pressure was 68 mmHg. ...
Song Yumi - - 2009
This study was performed to examine the vascular network of the human iris using flat preparation. The ciliary body-iris structures were separated from human eyeballs, and a portion of the irises were treated with trypsin to remove the pigment granules. These iris tissues were unfolded and placed onto glass slides ...
Lim Jong Yoon - - 2009
The purpose of this paper was to report a successful treatment of transluminal Nd:YAG laser embolysis (NYE) for branch retinal artery occlusion (BRAO) with visible emboli. Two patients with acute, severe vision loss secondary to a branch retinal artery occlusion with visible emboli in one eye underwent NYE. A complete ...
Papadaki Thekla - - 2009
We present a case of central retinal vein occlusion after an combined phacotrabeculectomy in a patient with advanced open angle glaucoma. Possible pathogenetic mechanisms for this complication are discussed.
McLeod David - - 2009
PURPOSE: The first definitive study of retinal vein occlusion complicated by infarction within the territory of one or more cilioretinal arteries was published in 1976. Many individual cases and further case series have been reported in the interim, but the nature of the interrelationship is still under debate. METHODS: A ...
Chang P-C - - 2010
Combined central retinal artery occlusion and central retinal venous occlusion have been rarely reported in patients with systemic lupus erythematosus and anti-phospholipid syndrome. The impact of this severe vaso-occlusive disease on vision is usually devastating and permanent in spite of vigorous treatment. We report herein a 35-year-old female patient displaying ...
Kotliar Konstantin - - 2010
Purpose. Image analysis by the retinal vessel analyzer (RVA) observes retinal vessels in their dynamic state online noninvasively along a chosen vessel segment. It has been found that high-frequency diameter changes in the retinal artery blood column along the vessel increase significantly in anamnestically healthy volunteers with increasing age and ...
Pinto Lancelot M - - 2009
A 75-year-old female was commenced on sildenafil for the treatment of pulmonary arterial hypertension (PAH) secondary to chronic obstructive pulmonary disease (COPD). She reported blurring of vision within 72 hours after starting treatment and was found to have a central retinal vein occlusion (CRVO). Such an occurrence is the second ...
Alp B N - - 2009
This study determined the prevalence of retinal arteriolar emboli risk factors in 148 patients (86 males) diagnosed with coronary artery disease who required coronary artery bypass graft surgery (mean +/- SD age 59.1 +/- 12.9 years). The prevalence of smoking was 50.7%, hypertension was 49.3%, diabetes mellitus was 27.0% and ...
Parodi Maurizio Battaglia - - 2009
An 83-year-old woman affected by nasal branch retinal vein occlusion with macular star underwent treatment with intravitreal triamcinolone acetonide injection followed by laser treatment addressed to the leaking vascular lesions. Visual acuity improved from 20/200 to 20/40 with a remarkable reduction of the macular exudates and resolution of dye leakage ...
Landa G - - 2010
AIMS: To describe different patterns of retinal collateral circulation observed in normal subjects and in patients with a variety of ocular diseases during studies with the retinal functional imager (RFI). METHODS: Normal subjects and patients with various ocular diseases underwent retinal blood flow imaging using the retinal functional imager. RESULTS: ...
Hayreh Sohan Singh - - 2009
To investigate systematically the various associated systemic and ophthalmic abnormalities in different types of retinal artery occlusion (RAO). Cohort study. We included 439 consecutive untreated patients (499 eyes) with RAO first seen in our clinic from 1973 to 2000. At first visit, all patients underwent detailed ophthalmic and medical history, ...
Beran David I - - 2009
This article provides a review of various conditions causing sudden, painless vision loss. The conditions of amaurosis fugax, central retinal artery occlusion (CRAO), central retinal vein occlusion (CRVO), vitreous hemorrhage, ischemic optic neuropathies (ION), posterior cerebrovascular accidents, and retinal detachment (RD) are discussed. The history, physical, pathophysiology, and treatment of ...
Morén Håkan - - 2009
PURPOSE: The aim of this study was to examine whether the retinal circulation in the pig can be accessed using interventional neuroradiology and to explore the possibility of creating occlusions that result in experimental retinal ischemia. METHODS: Six experiments were performed using 100-kg pigs. The external carotid system was catheterized ...
Sagara N - - 2009
AIM: To investigate the frequency and risk factors of macular hole (MH) formation after rupture of a retinal arterial macroaneurysm. METHODS: Fifty-six eyes from 56 patients with rupture of a retinal arterial macroaneurysm with or without an MH (MH and non-MH groups, respectively) were reviewed. Frequency and risk factors related ...
Shen Li-Jun - - 2009
PURPOSE: To investigate the feasibility of bypassing occluded segments of retinal arterial and venous main vessels in isolated, arterially perfused caprine eyes. MATERIALS AND METHODS: Eyecups of isolated caprine eyes were used. From each, the ophthalmic artery was separated and cannulated. Krebs solution was then perfused into the retinal vessel ...
Das-Bhaumik Raja G - - 2009
An asymptomatic 56 year old caucasian woman was referred when her optometrist noted an area of 'hyperaemia' in the centre of her right optic disc at a routine visit. On presentation, her visual acuities were 6/9 in each eye, with normal intraocular pressures. Fundoscopy revealed a right optic disc macroaneurysm. ...
Parsons J Travis - - 2009
Formation of bubbles in tissue and vasculature from a sudden reduction in ambient pressure is likely an underlying cause of the clinical symptoms of decompression sickness (DCS). Thus, tools detecting bubbles in the vasculature may be important for evaluating DCS. Sheep were air-compressed to 6.0 ATA (30 minutes bottom time) ...
Tagg Nathan T - - 2009
Combined central retinal vein and central retinal artery occlusion is a rare complication of compressive or infiltrative optic nerve disease. In this case combined retinal arterial and venous occlusive disease was the presenting sign of metastatic adenocarcinoma to the optic nerve sheath. An optic nerve sheath biopsy led to the ...
Zhang X - - 2009
OBJECTIVE: In this study, we aimed at exploring the effect and safety of local intra-arterial thrombolysis on acute central retinal artery occlusion. METHODS: Retrospective data analysis of 49 consecutive acute central retinal occlusion patients was performed. All the patients were treated with urokinase perfusion through the ophthalmology artery within the ...
von Hanno Therese - - 2010
Anti-vascular endothelial growth factor (anti-VEGF) therapy effectively inhibits angiogenesis and is now enjoying widespread use in the treatment of age-related macular degeneration (AMD). It may also have a role in the treatment of macular oedema secondary to other conditions. VEGF is a signalling molecule that has a variety of roles, ...
Politou Marianna - - 2009
We report a case of a 35-year-old previously healthy man treated with clomiphene for infertility, who presented with blurred vision in his left eye due to ocular vein occlusion as documented by fluorescein angiography. The patient was heterozygous for the factor V Leiden (FV Leiden) mutation and for the 1298 ...
Kofoed Peter Kristian - - 2009
PURPOSE: To examine variations in retinal vessel diameters during acclimatization of native highlanders to normobaric normoxia at sea level. METHODS: Fifteen healthy residents of the greater La Paz region in Bolivia (3600 m above sea level) were examined thrice over a 72-day period, after having traveled by airplane to Copenhagen, ...
Sugiyama Kazuhisa - - 2009
Takayasu disease was first reported in 1908 by Mikito Takayasu as "a case of peculiar changes in the central retinal vessels." Because in these patients the pulse of the radial artery is impalpable, investigations focusing on the ischemic symptoms of the upper body were conducted. In 1948, Shimizu and Sano ...
Lee Sang Joon - - 2009
We describe two cases of branch retinal artery occlusion (BRAO) after carotid artery (CA) stenting. Case 1: A 57-year-old man diagnosed with left neovascular glaucoma was admitted to our department for trabeculectomy (He had complained of decreased visual acuity (VA) in the left eye for a month). A preoperative neck ...
Seo Je Hyun - - 2009
A 44-year-old woman who showed recurrent vitreous hemorrhages with vascular tortuosity received CT angiography which revealed an internal carotid artery aneurysm. A case of internal carotid aneurysm was associated with a pattern of retinal arteriolar tortuosity pathognomic for familial retinal arterial tortuosity (fRAT), suggesting possible involvement of the cerebral circulation. ...
Chen Ying-Jen - - 2009
Central retinal artery occlusion is one of the most challenging practices and is not an infrequent presentation at the emergency department. We describe a 46-year-old man presenting with abrupt onset of amaurosis fugax secondary to sentinel central retinal artery occlusion followed by acute idiopathic renal infarction. This patient highlights that ...
Katsi Vasiliki - - 2010
We report a 31-year old woman with essential hypertension grade III and history of branch retinal vein occlusion in the setting of hyperhomocysteinemia due to homozygous MTHFR gene mutation and elevated Lp(a). The patient was treated successfully with antihypertensive treatment, acetylsalicylic acid and multivitamin complex supplementation.
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