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Rabczyński Maciej M Department of Angiology, Hypertension and Diabetology, Medical University in Wroclaw, Wrocław, Poland, - - 2014
Hypothenar hammer syndrome is a rare cause of ischemic fingers observed mainly in young men smoking cigarettes and it is associated with repeated trauma of the ulnar artery in the area of the hypothenar eminence of the dominant-hand arm, resulting in a deficit of blood supply with the occurrence of ...
Dehghani Payam P Clinical Co-Director, Prairie Vascular Research Network (PVRN), Unit 3A, Interventional Cardiology Research Office, Regina General Hospital 1440 - 14th Ave., Regina, Saskatchewan, S4P 0W5, - - 2014
We report a case of a 29-year-old man who developed exercised-induced myocardial infarction 3 months post Melody valve implantation. We introduce the concept of ruling out dynamic coronary artery compression by simulating transcatheter pulmonary valve implant while increasing cardiac output and thus aortic dimensions in the catheterization laboratory. © 2014 ...
Liang Ming M Department of Nephrology, Guangzhou First People's Hospital, Guangzhou Medical University, Guangzhou, - - 2014
Accumulation of smooth muscle cells (SMC) results in neointima formation in injured vessels. Two graft models consisting of vein and artery grafts were created by anastomosing common carotid arteries to donor vessels. To identify the origin of the neointima cells from anastomosed arteries, we use Wnt1-Cre/reporter mice to label and ...
Yuan Tian-Yi TY State Key Laboratory of Bioactive Substances and Functions of Natural Medicines, Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, 100050, - - 2014
In the present study, we investigated the vasodilatory effect of a novel scaffold Rho-kinase inhibitor, DL0805-2, on isolated rat arterial rings including mesenteric, ventral tail, and renal arteries. We also examined the potential mechanisms of its vasodilatory action using mesenteric artery rings. A DMT multiwire myograph system was used to ...
Chaoui R R Praxis, Pränataldiagnostik Friedrichstraße, - - 2014
In recent years the advent of high-resolution and color Doppler ultrasound has enabled a more comprehensive examination of the veins at the cardiac level. These veins include both the superior and inferior vena cava, the pulmonary veins, the azygos vein, the coronary sinus, and the brachiocephalic (or innominate) vein. This ...
Wang Hong H Department of Diagnostic Ultrasound, Dongfang Hospital, Fujian Medical University, Fuzhou, Fujian, 350002, People's Republic of - - 2014
From March 2007 to September 2009, we have screened with echocardiography a total of 6,502 pregnant women for fetal heart disease. We found three cases of fetal ventricular aneurysm. The relatively large size of the aneurysm in these three cases was clearly visible under standard four-chamber view. Two were right ...
Abid D D Cardiology Department, Hedi Chaker Hospital, El Ain street km 0,5, Sfax 3029, Tunisia. Electronic address: - - 2014
Left atrial thrombus in neonates is uncommon. We describe a newborn with coarctation of the aorta, in whom a thrombus confined to the left appendage was discovered on the first day of life and was thought to be a myxoma.
Gao Yunhe Y The Key Laboratory of Pathobiology, Ministry of Education, Norman Bethune College of Medicine, Jilin University, Changchun, 130021, Jilin, - - 2014
Tissue-engineered vessels offer options for autologous vascular grafts in cardiovascular repair and regeneration. The experiments aimed to construct functional arterial grafts by combining human hair follicle mesenchymal stem cells (HF-MSCs) with acellular umbilical arteries. We isolated mesenchymal stem cells from human hair follicles. Under appropriate culture conditions, these cells displayed ...
Chevalier Marc M Univ. Bordeaux, Centre de Recherche Cardio-Thoracique de Bordeaux, U 1045, F-33000 Bordeaux, France INSERM, Centre de Recherche Cardio-Thoracique de Bordeaux, 1045, F-33000, Bordeaux, - - 2014
Pulmonary hypertension (PH) is the main disease of pulmonary circulation. Alteration in calcium homeostasis in pulmonary artery smooth muscle cells (PASMC) is recognized as a key feature in PH. The present study was undertaken to investigate the involvement of T-type voltage gated calcium channels (T-VGCC) in the control of the ...
Souto Fernanda Maria FM Departamento de Medicina, Universidade Federal de Sergipe, São Cristóvão, Sergipe, Brasil. Electronic address: - - 2014
Anomalous pulmonary venous return (APVR) is a rare cardiac anomaly defined as one or more pulmonary veins draining into a structure other than the left atrium, with venous return directly or indirectly to the right atrium. The most common form is partial APVR, in which one to three pulmonary veins ...
Hawkes Cheryl A CA Clinical and Experimental Sciences, Faculty of Medicine, University of Southampton, Southampton, - - 2014
In Alzheimer's disease, amyloid-β (Aβ) accumulates as insoluble plaques in the brain and deposits in blood vessel walls as cerebral amyloid angiopathy (CAA). The severity of CAA correlates with the degree of cognitive decline in dementia. The distribution of Aβ in the walls of capillaries and arteries in CAA suggests ...
Tuluca Alexandra A Division of Cardiothoracic Surgery, the Michael E. DeBakey Department of Surgery, Baylor College of Medicine, Houston, Texas; Department of Cardiothoracic Surgery, The Michael E. DeBakey Veterans Affairs Medical Center, Houston, - - 2014
Iatrogenic aortic valve leaflet perforation and aorto-right atrial fistula are rare adverse events of transcatheter interventions and transseptal radiofrequency ablations, respectively. We present the case of a 62-year-old man who experienced acute, severe aortic insufficiency as a result of leaflet entrapment by a septal occluder device during attempted percutaneous closure ...
Muthalagan Elancheran - - 2014
Phosphatase and tensin analog (PTEN) gene mutation has been proven for pro-inflammatory property and proliferative potential through tyrosine kinase pathway. We studied mutated PTEN for its pathogenetic association in arterial atherosclerosis. The objective was to study mutation of PTEN by immunohistochemical method in arterial atherosclerotic lesions and correlate with grades ...
Chen Bernadette B The Research Institute at Nationwide Children's Hospital - - 2014
Pulmonary artery smooth muscle cell (PASMC) proliferation plays a fundamental role in the vascular remodeling seen in pulmonary hypertensive diseases associated with hypoxia. Arginase II, an enzyme regulating the first step in polyamine and proline synthesis, has been shown to play a critical role in hypoxia-induced proliferation of human pulmonary ...
Guo Haipeng H Department of Critical Care Medicine, Qilu Hospital of Shandong University, Jinan 250012, China; Key Laboratory of Cardiovascular Remodeling and Function Research, Chinese Ministry of Education and Chinese Ministry of Health, Qilu Hospital ofShandongUniversity, Jinan 250012. - - 2014
Increased pulmonary arterial smooth muscle cells (PASMCs) proliferation is a key pathophysiological component of pulmonary vascular remodeling in pulmonary arterial hypertension (PAH). Isorhynchophylline (IRN) is a tetracyclic oxindole alkaloid isolated from the Chinese herbal medicine Uncaria rhynchophylla. It has long been used clinically for treatment of cardiovascular and cerebrovascular diseases. ...
Wu Yuanyuan Y Department of Respiratory Medicine, Respiratory Diseases Research Center, The Second Affiliated Hospital of Medical College, Xi'an Jiaotong University, Xi'an, Shaanxi, PR - - 2014
ABSTRACT The aims of the present study were to examine the effect of AMPK activation on pulmonary arterial smooth muscle cells (PASMCs) proliferation and to address its potential mechanisms. ET-1 dose and time-dependently induced PASMCs proliferation, and this effect was suppressed by a selective AMPK activator metformin. The results of ...
Patel Nimesh R NR From the Department of Pathology & Immunology, Baylor College of Medicine, Houston, Texas (Drs Patel and Elghetany); Medical Examiner Service, Harris County Institute of Forensic Sciences, Houston, Texas (Dr Anzalone); the Department of Pathology & Laboratory Medicine, The University of Texas Health Science Center at Houston (Dr Buja); and the Department of Pathology, Texas Children's Hospital, Houston (Dr - - 2014
Immunoglobulin G4-related disease (IgG4-RD) is a systemic disorder characterized by multiorgan fibrosis with IgG4-producing plasma cells, increased IgG4 serum concentration, and responsiveness to steroid therapy. Involvement of the pancreas, salivary glands, orbit, aorta, and other sites has been well documented in the literature; however, there have been limited reports of ...
Jothidasan Anand A Cardiothoracic Department, Royal Brompton Hospital, Imperial College, London, United - - 2014
Left atrial intramural hematoma is a rare complication of percutaneous intervention. We report the case of a 69-year-old man with recurrent angina after CABG 19 years ago who was admitted for percutaneous intervention. After an attempt to recanalize the native circumflex artery and the vein graft, he had a cardiac ...
El-Segaier Milad - - 2014
Cardiac rhabdomyomas are rare and often regress spontaneously. However, the management of rhabdomyoma with severe inflow and outflow obstructions is a challenge. An infant with a massive left ventricular rhabdomyoma mimicking the haemodynamics of hypoplastic left heart syndrome is reported. Surgery could not be contemplated because the mitral valve leaflets ...
Sumalatha Suhani S Senior Grade Lecturer, Department of Anatomy, Kasturba Medical College, Manipal University, Manipal , Karnataka, India - - 2014
The Popliteal Artery (PA), which is the continuation of the Femoral artery, crosses the popliteal fossa at the distal border of popliteus; it divides into the Anterior and Posterior Tibial arteries. The Posterior Tibial Artery (PTA) divides into terminal branches proximal to popliteus, in which case the Anterior Tibial Artery ...
Luo Y Y 1] Department of Pathophysiology and High Altitude Physiology, Third Military Medical University, Chongqing, China [2] Key Laboratory of High Altitude Medicine, Ministry of Education, Third Military Medical University, Chongqing, China [3] Key Laboratory of High Altitude Medicine, PLA, Third Military Medical University, Chongqing, China [4] Department of Pathology and Pathophysiology, Fourth Military Medical University, Xi'an, China [5] Lung Injury and Repair Center, Fourth Military Medical University, Xi'an, - - 2014
Hypoxia-induced proliferation of pulmonary artery smooth muscle cells (SMCs) is important in the development of hypoxic pulmonary hypertension (HPH). We constructed a lentivirial vector containing a smooth muscle-specific promoter and six copies of hypoxia response element to co-drive the expression of p27, the key cyclin-dependent kinase inhibitor that blocks the ...
Sürer Süleyman S Department of Cardiovascular Surgery, Bursa Yuksek Ihtisas Education and Research Hospital, Bursa, Turkey - - 2014
In the present study, we aimed to deterimine the dose-related effects of ticagrelor, the first reversible inhibitor of the P2Y12 receptor, found in smooth muscle cells as well as platelets, during neointimal hyperplasia in a rabbit carotid anastomosis model. This study was an experimental, prospective, randomized controlled study including 20 ...
Kanemitsu Shinji S Department of Thoracic and Cardiovascular Surgery, Mie University Graduate School of Medicine, Mie, Japan - - 2014
Cardiac lipomas are extremely rare benign tumors. They usually remain asymptomatic and are detected incidentally. We report an unusual case of a 60-year-old man who presented with a large epicardial lipoma found unexpectedly during coronary artery examinations. Coronary angiography revealed advanced 3-vessel coronary artery disease. We successfully performed simultaneous curative ...
Spencer Julianne H JH Department of Biomedical Engineering, University of Minnesota, Minneapolis, Minnesota; Medtronic, Inc., Minneapolis, Minnesota; Institute for Engineering in Medicine, University of Minnesota, Minneapolis, - - 2014
An anatomical understanding of human coronary arterial and venous systems is necessary for device development and therapy applications that utilize these vessels. We investigated the unique use of contrast-CT scans from perfusion-fixed human hearts for three-dimensional visualization and analysis of anatomical features of the coronary systems. The coronary arterial and ...
Garrido Jose M JM Department of Cardiac Surgery, European University of Madrid, Ramón y Cajal Hospital, Madrid, - - 2014
Transcatheter aortic valve implantation (TAVI) is associated with various complications, usually related to valve positioning or prosthesis delivery. We report the rare complication of an iatrogenic ventricular septal defect, secondary to aortic annulus disruption after TAVI-transfemoral procedure, generating a significant left-to-right shunt and cardiac failure. Open surgical procedures under cardiopulmonary ...
Hootnick David D SUNY Upstate Medical University, Taft Road, Liverpool, United - - 2014
Birth Defects Research (Part A), 2014. © 2014 Wiley Periodicals, Inc.
Jerzewski Katie K Lynn Heart and Vascular Institute, Boca Raton Regional Hospital, Boca Raton, Florida; Charles E. Schmidt College of Medicine, Florida Atlantic University, Boca Raton, - - 2014
Acute type A aortic dissection complicated by cardiac tamponade portends a lethal prognosis. We report the unusual case of an older female who unexpectedly survived for more than one year after presentation with acute dissection and tamponade. She was treated with a pericardial window and remains alive now four years ...
Gaynullina Dina - - 2014
Pannexin1 is ubiquitously expressed in vertebrate tissues, but the role it plays in vascular tone regulation remains unclear. We found that Pannexin1 expression level is much higher in the endothelium relative to smooth muscle of saphenous artery. The ability of endothelium-intact arteries for dilation was significantly impaired whereas contractile responses ...
Sur Swastika S a Department of Biomedical Science, Creighton University School of Medicine, 2500 California Plaza, Omaha, NE 68178, - - 2014
Proliferation and migration of smooth muscle cells and the resultant intimal hyperplasia cause coronary artery bypass graft failure. Both internal mammary artery and saphenous vein are the most commonly used bypass conduits. Although an internal mammary artery graft is immune to restenosis, a saphenous vein graft is prone to develop ...
Costanzo Luca L Department of Pediatric Cardiology and Cardiac Surgery, Bambino Gesù Children's Hospital Centro Cardiologico Pediatrico del Mediterraneo, San Vincenzo Hospital, Taormina, - - 2014
We report the case of a 2-month-old baby with a double aortic arch, type C atresia of the left arch and severe hypoplasia of the right aortic arch between the right carotid and sub-clavian arteries, resulting in systemic obstruction, left ventricular dysfunction and congestive heart failure. Surgical augmentation of the ...
Maroules Christopher D - - 2014
Cardiovascular magnetic resonance (CMR) has been validated for the noninvasive assessment of total arterial compliance and aortic stiffness, but their associations with cardiovascular outcomes is unknown. The purpose of this study was to evaluate associations of CMR measures of total arterial compliance and two CMR measures of aortic stiffness with ...
Deb Partha Pratim PP Department of Biomedical Engineering, Case Western Reserve University, Cleveland, OH, - - 2014
Spatiotemporal changes in the extracellular matrix (ECM) were studied within abdominal aortic aneurysms (AAAs) generated in rats via elastase infusion. At 7, 14 and 21 days post-induction, AAA tissues were divided into proximal, mid- and distal regions, based on their location relative to the renal arteries and the region of ...
Romaniello Federico F Institute of Anatomic Pathology, Dept. of Biomedicine and Prevention, Tor Vergata University of Rome, Via Montpellier, 00133 Rome, - - 2014
Marfan syndrome (MFS) is an inherited autosomal dominant multisystem disease caused by mutations in the FBN1 gene encoding fibrillin-1, an extracellular matrix glycoprotein widely distributed in mesenchymal-derived tissues that provide a scaffold for elastin deposition. MFS is characterized by variable clinical manifestations, including skeletal, ocular, and cardiovascular abnormalities; ascending aortic ...
Kim Tae Nam TN Department of Urology, Pusan National University Hospital, Busan, - - 2014
A 29-year-old woman with mild back pain when coughing and suprapubic discomfort after voiding was admitted to Pusan National University Hospital. Two weeks earlier, she had undergone a hysterectomy and right-sided ureteroneocystostomy for uterine atony and right ureteral injury with bladder rupture. Computed tomography showed that a ureteral J stent ...
Singhi Anil Kumar AK Department of Pediatric Cardiology, Madras Medical Mission, Mogappair, Chennai, - - 2014
While aortico-right atrial tunnels with left to right shunt from aorta to right atrium are reported widely, pulmonary artery to right atrial tunnels have not been described so far. Such a tunnel will lead to a circular shunt with a recirculation of blood in the right sided cardiac chambers repeatedly ...
Barik Ramachandra R Department of Cardiology, Nizam's Institute of Medical Sciences, Hyderabad, Andhra Pradesh, - - 2014
Pseudoaneurysm of ascending aorta after cardiac surgery is rare in children. We report a case of successful surgical exclusion of ascending aortic pseudoaneurysm in a 15-year-old boy. The neck of the aneurysm was in close proximity to the right coronary artery (RCA).
Prestipino Filippo F Department of Cardiovascular Science, Cardiovascular Surgery Unit, University Campus Bio-Medico of Rome, Rome, - - 2014
Anomalous origin of the left coronary artery originating from the opposite sinus of Valsalva is a coronary anomaly with a consistently low prevalence rate. Different patterns have been described for this type of anomaly with respect to the position and course of the coronary arteries. The interarterial type can be ...
Kong Haiying Y - - 2014
Central venous catheterization can be necessary for patients undergoing a cardiac operation. Accidental suturing of the catheter to the heart is a rare complication that is difficult to correct; excessive traction force on the central venous catheter can lead to heart breakage or even death. We describe the case of ...
Weizsäcker Hans W - - 2014
Abstract Highly diluted solutions of Gentian Violet and Evans Blue were used to visualize the elastin network in viable porcine right common carotid artery (RCCA) preparations. The two simple, alternative methods of staining were applied to proximal, intermediate, and distal sections of RCCA under various experimental conditions. These included the ...
Xiao Yong Guang YG Department of Thoracic Surgery, Renmin Hospital of Wuhan University, Wuhan, Hubei Province, - - 2014
The proliferation and high plasticity of vascular smooth muscle cells (vSMCs) are the major reasons for restenosis of vein grafts. N-[N-(3, 5-difluorophenacetyl)-l-alanyl]-S-phenylglycine t-butyl ester (DAPT), specific inhibitor of γ-secretase, has been shown to regulate vSMC proliferation and differentiation through the Notch signaling pathway, but the pathophysiological importance of these findings ...
Rajesh Gopalan Nair GN Additional Professor, Department of Cardiology, Government Medical College, Kozhikode, Kerala 673008, India. Electronic address: - - 2014
Hammock valve, also known as anomalous mitral arcade is a rare mechanism for congenital mitral insufficiency. We report a case of a two-week-old neonate who presented with features of heart failure and an apical systolic murmur. Echocardiogram showed severe mitral regurgitation and abnormal mitral valve with direct attachment of mitral ...
Ashraf Omer O Department of Cardiothoracic Surgery, The Townsville Hospital, Douglas, - - 2014
Mechanical valve failure is a known but rare occurrence in cardiac surgery. A 71-year-old lady underwent surgery for failure of her mechanical aortic valve. It was replaced with another mechanical valve. However, during operative manipulation, both leaflets fractured, resulting in a prolonged operative time. Under these circumstances, a novel approach ...
Al-Maskari Salim S Senior Consultant, Department of Pediatric Cardiology, Royal Hospital, Muscat 111, - - 2014
Native aortic valve or its prosthetic valve endocarditis can extend to the adjacent periannular areas and erode into nearby cardiac chambers, leading to pseudoaneurysm and aorta-cavitary fistulas respectively. The later usually leads to acute cardiac failure and hemodynamic instability requiring an urgent surgical intervention. However rarely this might pass unnoticed ...
Alattar Mohamed M Department of Cardiothoracic Surgery, Zagazig University, Ash Sharqiyah, - - 2014
Development of intimal hyperplasia (IH) is the main pathology underlying graft failure following coronary artery bypass graft surgeries for ischaemic heart diseases, especially for great saphenous vein grafts which have a lower patency rate than internal mammary arteries. Neuropilin 1 (NRP1), which is a co-receptor for vascular endothelial growth factor ...
Ooi Chen Yen CY Department of Engineering, University of Cambridge, - - 2014
Our aim was to determine whether alterations in biomechanical properties of human diseased compared to normal coronary artery contributes to changes in artery responsiveness to endothelin-1 in atherosclerosis. Concentration-response curves were constructed to endothelin-1 in normal and diseased coronary artery. The passive mechanical properties of arteries were determined using tensile ...
Okpala Ogechukwu O From the Department of Neurology, Addenbrooke's Hospital, Cambridge University Hospitals, Cambridge Biomedical Campus, - - 2014
A 63-year-old man presented with headache, hoarseness, and dysphagia. He had a left-sided Horner syndrome and wasting of the left sternocleidomastoid muscle. His tongue was deviated to the left on protrusion (figure 1). MRI and CT angiography revealed a distal left internal carotid artery dissection (figure 2).
Joshi Shreedhar S SS Department of Cardiac Anesthesia, Sri Jayadeva Institute of Cardiovascular Sciences and Research, Bengaluru, Karnataka, - - 2014
Pseudoaneurysm of mitral-aortic intervalvular fibrosa (P-MAIVF) is a rare cardiac surgical condition. P-MAIVF commonly occurs as a complication of aortic and mitral valve replacement surgeries. The surgical trauma during replacement of the valves weakens the avascular mitral and aortic intervalvular area. We present a case of P-MAIVF recurrence 5 years ...
Porras-González Cristina C Instituto de Biomedicina de Sevilla (IBiS) and Departamento de Fisiología Médica y Biofísica, Hospital Universitario Virgen del Rocío/CSIC/Universidad de Sevilla, Seville, - - 2014
L-type Ca(2+) channels (LTCCs) are involved in the maintenance of tonic arterial contractions and regulate the RhoA/Rho-associated kinase (ROCK) sensitization cascade. We have tested the effects of individual and combined low concentrations of LTCCs and ROCK inhibitors to produce arterial relaxation without the adverse side effects of LTCCs antagonists. We ...
Padhye Vikram V Department of Surgery-Otolaryngology Head and Neck Surgery, University of Adelaide/The Queen Elizabeth Hospital, Woodville South, South Australia, - - 2014
The most dreaded hemorrhagic complication in endoscopic endonasal surgery is injury to the internal carotid artery (ICA). Although a number of treatment protocols are currently used, none have been formally investigated. This study aims to compare the efficacy of the muscle patch, bipolar diathermy, and aneurysm clip on hemostasis, pseudoaneurysm ...
Yuan Li-Jun - - 2014
Cardiovascular adaptions, such as cardiac and uterine spiral arterial remodeling, and aortic arterial stiffening during pregnancy have been extensively investigated, while the interactions between the elastic artery and the left ventricle are poorly understood. This study was to evaluate the cardiac-arterial coupling in both normal pregnancy and preeclampsia using ultrasound ...
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