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Aydin Suna S Elazig Research and Education Hospital, Clinic of Cardiovascular Surgery, Elazig, 23119 Turkey ; School of Medicine, Department of Anatomy, Firat University, Elazig, 23119 - - 2013
Blood is pumped into the cardiac muscle through arteries called the coronary arteries. Over time, the accumulation of cholesterol, coagulation factors, and cells on the walls of these arteries causes the walls to thicken and lose their elasticity, resulting in the development of atherosclerosis. When the blood supply of the ...
Casullo Joseph - - 2013
CT scans in four cases of chronic superior vena cava or left brachiocephalic vein obstruction demonstrate a systemic-to-cardiac collateral venous pathway through anastomoses between the pericardial branches of systemic veins and the presumed adventitial veins of the ascending aorta and pulmonary trunk. These adventitial veins then drain into tributaries of ...
Sousa Pedro Jerónimo - - 2012
We report the case of a 40-year-old man with known Marfan syndrome who presented with severe aortic valve regurgitation secondary to significant aortic root dilatation. To rule out coronary artery disease and to evaluate the rest of the thoracic aorta before surgery, cardiac computed tomography (CT) was performed. A brief ...
Ren Pingping P Division of Cardiothoracic Surgery, Michael E. DeBakey Department of Surgery, Baylor College of Medicine, Houston, Texas, - - 2013
ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) is a recently identified family of extracellular metalloproteinases that has been shown to participate in tissue destruction. We hypothesized that ADAMTS-1 and ADAMTS-4 expression is increased in aortic tissues from patients with thoracic aortic aneurysms and dissections. We examined ADAMTS-1 and ADAMTS-4 ...
Kettner Mattias - - 2012
Coronary artery anomalies are found in approximately 1.3 % of symptomatic adult patients undergoing coronary arteriography and encompass a wide variety of anatomic patterns. Single coronary arteries are found in 0.024-0.066 % of this group. The particular type of a single coronary artery with an anatomically correct course of either artery (so-called ...
Arima Yuichiro - - 2012
Neural crest cells constitute a multipotent cell population that gives rise to diverse cell lineages. The neural crest arising from the postotic hindbrain is known as the 'cardiac' neural crest, and contributes to the great vessels and outflow tract endocardial cushions, but the neural crest contribution to structures within the ...
Weber Tobias - - 2012
Background: It is mostly agreed that arterial adaptations occur, among others, in response to changes in mechanical stimuli. Models like bed rest, spinal cord injury or limb suspension have been applied to study vascular adaptations to unloading in humans. However, these models cannot distinguish the role of muscle contractions and ...
Tverskaya M S - - 2012
Metabolism of contractile cardiomyocyte in experimental pulmonary stenosis complicated or not complicated by heart failure was studied by histochemical methods. In pulmonary stenosis not complicated by heart failure, intensification of glycolysis, more intense oxidation of free fatty acids and their metabolites, and acceleration of the citric acid cycle were found ...
Mazur Lynnette - - 2012
We report a case of a 13-year old girl with pectus excavatum who had a Nuss procedure and two years later a new cardiac murmur appeared which on investigation was diagnosed as supravalvular pulmonary artery stenosis. Following removal of the Nuss bar the stenosis resolved.
Whiteley Joseph R - - 2012
A case of a 49 year old man with a giant basilar artery aneurysm requiring rapid ventricular pacing is presented. Rapid ventricular pacing decreased aneurysm size and increased operative exposure, which aided surgical decision making. It also provided decreased wall tension in the aneurysm.
Scaglione Frine E - - 2012
A 2-yr-old male Siberian Tiger (Panthera tigris altaica) died during a fight with a conspecific. At necropsy, significant abnormalities included severe cardiomegaly with cardiac malformations consisting of a large atrial septal defect, a membranous ventricular septal defect, overriding aorta, and stenosis of the pulmonary valve with secondary concentric hypertrophy of ...
Le Victoria P - - 2012
Decreased expression of elastin results in smaller, less compliant arteries and high blood pressure. In mice, these differences become more significant with postnatal development. It is known that arterial size and compliance directly affect cardiac function, but the temporal changes in cardiac function have not been investigated in elastin insufficient ...
Jacobs Marshall L - - 2012
Hearts having a common arterial trunk belong to a family of congenital cardiac malformations for which traditional systems of classification and nomenclature are plagued by internal paradoxes, incompatibility between systems due to the lack of potential for identification of synonyms, or irreconcilable inconsistencies with our current knowledge of cardiac development ...
Aykut Koray - - 2012
A 32-year-old man was urgently referred to our hospital with severe tricuspid insufficiency following a car accident. The completely flail anterior leaflet, due to the rupture of the papillary muscles, was revealed by a two-dimensional transthoracic echocardiography. In the operation, we also detected a tear on the anterior leaflet and ...
Bae Sang Mook - - 2012
We examined a 63-year-old woman with progressive dyspnea. Two years prior to admission to our hospital, she had been diagnosed with rheumatoid arthritis and treated with hydroxychloroquine (HCQ) with a cumulative dose of 164 g. In addition, 2 months earlier, she had been diagnosed with connective tissue disease-related pulmonary artery ...
Munger Stephanie J SJ Department of Physiology, University of Arizona, Tucson, AZ 85724, USA. - - 2013
Venous valves play a crucial role in blood circulation, promoting the one-way movement of blood from superficial and deep veins towards the heart. By preventing retrograde flow, venous valves spare capillaries and venules from being subjected to damaging elevations in pressure, especially during skeletal muscle contraction. Pathologically, valvular incompetence or ...
Yoshino Satoshi - - 2012
A 68-year-old woman was admitted to our hospital because of back pain and syncope. Transthoracic echocardiography revealed pericardial effusion, a collapsed right ventricle, a giant aneurysm connected to the coronary sinus, a dilated left main trunk coronary artery, and a dilated left circumflex artery (LCx). Furthermore, there was a coronary ...
Mikhailidis Dimitri P - - 2012
The lecture covered the role of lipids in the pathogenesis and treatment of non-cardiac vascular disease. The following conditions were considered: abdominal aortic aneurysms (AAAs), peripheral arterial disease (PAD), carotid artery disease and atherosclerotic renal artery stenosis (ARAS).
Kang Xiao-Long - - 2012
The purpose of the present study was to compare the differences between the role of volume-regulated Cl(-) channels (VRCCs) in veins and arteries. We used the whole cell patch clamp and fluorescence imaging techniques to evaluate swelling-induced Cl(-) current (I(Cl,vol)) and changes in the intracellular concentrations of Cl(-) ([Cl(-)](i)) induced ...
Jo Yong Woo - - 2012
ABSTRACT: The aim of this study was to elucidate the precise anatomy of the perforating branch of the superficial temporal artery in relation to subcutaneous forehead lift (SFL).Ten hemifaces of 6 fresh adult Korean cadavers were used in this study. In 4 hemifaces, following injection of red latex, dissection was ...
Chen Gang - - 2012
Conjoined twins are very rare examples of congenital malformations. In 75% of thoracoomphalopagus conjoined twins, the intracardiac anatomy determines outcome and long-term survival. We successfully separated one case of thoraco-omphalopagus conjoined twins, with one having d-transposition of the great arteries. After control of sepsis, the twin underwent an arterial switch ...
Bi Yonghua - - 2012
The objective of this study was to determine the possibility of creating a novel animal model of abdominal aortic aneurysm (AAA) in rabbits by the periarterial application of papain. Twelve New Zealand white rabbits were randomized into two groups: (1) the papain group, which received 2mg of papain (n=8) and ...
Schleger Simone - - 2012
Primary cardiac malignancies are rare, and the majority are benign. Malignant tumors are often found to be sarcomas arising from structural cells such as muscle, connective tissue, and blood vessels. We report a case of a 62-year-old woman who presented with pulmonary embolism secondary to a primary pulmonary artery chondrosarcoma. ...
Kumar Naveen - - 2012
Variations in the venous pattern of the arm are common. In this case report, we are presenting the variations of the brachial vein and the basilic vein.During the routine dissections which were done by medical undergraduate students, we observed some variations in the veins of the upper limb. In the ...
Fouillade Charles C INSERM, U740, Paris, - - 2013
Notch3 is critically important for the structure and myogenic response of distal arteries, particularly of cerebral arteries. However, signaling pathways acting downstream of Notch3 remain largely unknown. Transcriptome analysis using tail arteries of Notch3-null mice identified a core set of 17 novel Notch3-regulated genes confirmed in tail or brain arteries. ...
Moustafa Sherif - - 2012
Aneurysms of sinus of Valsalva are rare congenital or acquired cardiac anomalies. They most commonly involve the right or non-coronary sinuses. Herein we report a very rare case of a ruptured congenital right sinus of Valsalva aneurysm into the right ventricular outflow tract followed conservatively for at least 10 years ...
Rahman Awahan - - 2012
Huntington's disease is a neurodegenerative disorder that also gives raise to widespread changes in peripheral organs and tissues. We tested the hypothesis that vascular dysfunction may occur in Huntington's disease by studying R6/1 mice which express exon 1 of the mutant huntingtin gene. We assessed arterial function in R6/1 and ...
Troupis John M - - 2013
After the advent of ECG gated cardiac CT angiography (CCTA) there has been significant improvement in image quality of the ascending aorta. As a result the sinuses of valsalva are readily assessable. Sinuses of valsalva aneurysm can cause significant dysfunction of the aortic root and annulus and can be congenital ...
Boldt Jessica - - 2012
Objective: The aim of tissue engineering is, for instance, to create a new valve or organ which is similar to the native one. This new construct may have the capability of growth, repair and remodelling. One instance were tissue engineering offers an enormous advantage is in the treatment of Tetralogy ...
Agrifoglio Marco - - 2012
Abstract  The widely used peripheral vein site of cannulation (i.e., the femoral vein) cannot always be employed in the setting of re-redo procedures. We propose a safe and simple surgical technique for a femoral vein cannulation using the greater saphenous vein as the inflow tract for the venous drainage in ...
Klimek-Piotrowska Wiesława - - 2012
During a routine dissection at the Department of Anatomy, Collegium Medicum, Jagiellonian University, one cadaver was found to have multiple variations of the arteries of the upper limbs. The variations pertained to the course of the brachial artery as well as to its distribution. An unusual formation of the superficial ...
Rayoo R - - 2012
Partial anomalous pulmonary venous drainage is a rare congenital anomaly which can lead to right heart enlargement. It may present in isolation or more commonly in association with other congenital cardiac anomalies. We present three different cases of partial anomalous pulmonary venous drainage in adults. The importance of identifying partial ...
Gunnal S A - - 2012
The mitral valve is a complex structure that is altered by disease states. The classical image of the mitral valve is a bicuspid valve with two leaflets and two papillary muscles. The reason for the present study is to study the morphology and morphometry of the mitral valve. This study ...
Ishii Yoichiro - - 2012
Objectives: To investigate the 'I-shaped' sign as a novel echocardiographic marker for antenatal diagnosis of d-transposition of the great arteries (dTGA) in routine cardiac examination, and to compare its prevalence in dTGA, other congenital heart diseases (CHDs), and normal structural hearts. Methods: This retrospective evaluation involved 1,134 pregnant women undergoing ...
Stein Andreas - - 2012
This report presents a case of pulmonary air embolism during implantation of a cardiac resynchronisation therapy system. For left ventricular pacing the thinnest available coronary sinus lead was used in association with a standard subclavian vein introducer sheath. It is hypothesised that the difference of size between the small lead ...
Duan Bin - - 2012
Heart valve disease is a serious and growing public health problem for which prosthetic replacement is most commonly indicated. Current prosthetic devices are inadequate for younger adults and growing children. Tissue engineered living aortic valve conduits have potential for remodeling, regeneration, and growth, but fabricating natural anatomical complexity with cellular ...
Papangeli Irinna I UCL-ICH, 30 Guilford St, London WC1N 1EH, - - 2013
Growth and remodeling of the pharyngeal arch arteries are vital for the development of a mature great vessel system. Dysmorphogenesis of the fourth arch arteries can result in interruption of the aortic arch type B, typically found in DiGeorge syndrome. Tbx1 haploinsufficient embryos, which model DiGeorge syndrome, display fourth arch ...
Leclère Franck Marie - - 2012
OBJECTIVES/HYPOTHESIS: The use of the sternocleidomastoid (SCM) flap for reconstructive surgery of the mandible seems to be a practicable although underestimated option. STUDY DESIGN: This study was conducted on 15 cadavers that had been neoprene-latex injected in the middle and inferior pedicles. METHODS: Lengths of the SCM were equally divided ...
Hubbell Margaret C MC Divisions of Physiology, Pharmacology, and Biochemistry, Center for Perinatal Biology, Loma Linda University Schoolof Medicine, Loma Linda, California 92350, - - 2012
Chronic hypoxia increases vascular endothelial growth factor (VEGF) and thereby promotes angiogenesis. The present study explores the hypothesis that hypoxic increases in VEGF also remodel artery wall structure and contractility through phenotypic transformation of smooth muscle. Pregnant and nonpregnant ewes were maintained at sea level (normoxia) or 3,820 m (hypoxia) ...
Arraut Amaryllis Maria Elpida - - 2012
Objective: We tested the hypothesis that fetal pulmonary arterial circulation reacts to changes in fetal oxygenation status at near-term gestation. Study Design: A total of 20 rhesus macaques underwent fetal Doppler ultrasonography at near-term gestation. Right pulmonary artery (RPA), umbilical artery (UA), ductus arteriosus (DA), and ductus venosus (DV) blood ...
Stefańczyk Ludomir - - 2012
Osteolysis of vertebrae due to inflammatory aortic aneurysm is rarely observed. However, it is estimated that up to 10 % of infectious aneurysms coexist with bone tissue destruction, most commonly the vertebrae. Inflammatory aneurysms with no identified infection factor, along with infiltration of adjacent muscle and in particular extensive destruction of ...
Ayabakan Canan - - 2012
Crisscross heart is a rare congenital cardiac anomaly in which systemic and pulmonary venous streams cross without mixing at atrioventricular level. We report a case of crisscross heart with tricuspid atresia, double outlet right ventricle, and pulmonary stenosis, which was diagnosed prenatally.
Wang Yutang - - 2012
Abdominal aortic aneurysms (AAAs) are common problems in aged people which can be associated with severe complications including aortic rupture and death. Transforming growth factor-β (TGFβ) has been implicated as causative in the development of thoracic aortic aneurysms (TAAs). In contrast, current evidence suggests TGFβ inhibits AAA development. Polymorphisms in ...
John Lindsay C H - - 2012
In coronary artery bypass surgery the most commonly used conduit for grafting the left anterior descending artery is the left internal mammary artery. In harvesting the internal mammary artery the parietal pleura is frequently breached. This is associated with increased post operative complications. The diaphragm is not in contact with ...
Fathala Ahmed - - 2012
Ruptured sinus of Valsalva aneurysm is an uncommon condition with variable manifestation that results in aortocardiac shunt. The presentation may range from an asymptomatic murmur to cardiogenic shock. The initial diagnosis is established or suspected by two-dimensional echocardiography and colour flow Doppler. Transesophageal echocardiography is especially helpful in delineating the ...
Kim Da-Hye - - 2012
ABSTRACT: The purpose of the present study was to provide precise data regarding the branching pattern of the submental artery, which should be considered in occasions of bleeding during various dentoalveolar surgical procedures of the mandible, such as implant surgeries, tori removal, and iatrogenic injuries.Twenty-six embalmed adult hemifaces from Korean ...
Kim Yeon-Hwa - - 2012
Passage failure of guidewire is still remained most common reason for percutaneous coronary intervention (PCI) failure in chronic total occlusion (CTO). Intravascular ultrasound study (IVUS) and cardiac CT angiography can help identify features that most influence current success rates of PCI. We report our experience using the reverse controlled antegrade ...
George Peter M PM Cardiothoracic Pharmacology, National Heart and Lung Institute, Imperial College London, Dovehouse Street, London, United - - 2012
Pulmonary arterial hypertension (PAH) is a rare but fatal condition in which raised pulmonary vascular resistance leads to right heart failure and death. Endothelin-1 is a potent endogenous vasoconstrictor, which is considered to be central to many of the events that lead to PAH, and is an important therapeutic target ...
Hwang Kyu Tae - - 2012
The thoracodorsal artery perforator flap is a versatile flap for the reconstruction of various soft tissue defects. Several anatomical variations of thoracodorsal artery have been described and an "accessory thoracodorsal artery" which has a separate and direct origin from the axillary artery has been reported. In this report, we describe ...
Jappar Ignasius Aditya - - 2012
Anomalous origin and course of coronary arteries (AOCA) is a potential cause of sudden cardiac death. Coronary CT angiography (coronary CTA) enables detailed 3-dimensional visualization of AOCA. Data are limited about the diagnostic performance of noncontrast cardiac CT obtained during coronary calcium scan for detecting AOCA. We assessed the feasibility ...
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