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Sansone F - - 2013
We describe an additional use of the Foley catheter for preoperative and postoperative evaluation of the regurgitant mitral valve.
Joshi Devendra D From the *Division of Cardiac Surgery, and †Columbia University Division of Cardiology, Mount Sinai Heart Institute, Miami Beach, FL - - 2013
Herein, we report the case of a 60-year-old woman who presented with increasing dyspnea on exertion. Echocardiography revealed significant aortic and mitral regurgitation, which were most likely secondary to previous radiation therapy for breast cancer. On cardiac catheterization a 90% ostial right coronary artery lesion was found and treated with ...
Landes Constantin - - 2013
In this report, we present a case of a prelaminated radial forearm flap in reconstruction of a large persistent cleft palate with transoral single arterial and three venous anastomoses. A 17-years-old female patient presented a large cleft palate defect and complete dentition, dysmelia of both arms and bilateral thumb aplasia. ...
Hascoet Sébastien S Pediatric Cardiology Unit, Hôpital des enfants, Toulouse, France. Electronic address: - - 2013
Right ventricle-dependent coronary circulation significantly alters the therapeutic options and prognosis in neonates with pulmonary atresia and intact ventricular septum. The contribution of cardiac computed tomography for the accurate assessment of multiple coronary arteries to right ventricle fistulas in a newborn infant with pulmonary atresia and intact ventricular septum is ...
Paffett-Lugassy Noëlle N 1] Cardiovascular Research Center, Massachusetts General Hospital, Charlestown, Massachusetts 02129, USA [2] Harvard Medical School, Boston, Massachusetts 02115, USA [3] Harvard Stem Cell Institute, Cambridge, Massachusetts 02138, - - 2013
The pharyngeal arch arteries (PAAs) are transient embryonic blood vessels that make indispensable contributions to the carotid arteries and great vessels of the heart, including the aorta and pulmonary arteries. During embryogenesis, the PAAs appear in a craniocaudal sequence to connect pre-existing segments of the primitive circulation after de novo ...
Peng Gongyong - - 2013
Pulmonary endothelial dysfunction plays an integral role in the pathogenesis and development of pulmonary hypertension. It is difficult and inconvenient to obtain pulmonary arterial endothelial cells (PAECs) from humans and large animals. Some methods for the isolation of PAECs from rats require complex equipment and expensive reagents. In this study, ...
Guihaire Julien - - 2013
Ventricular-arterial coupling is a measure of the relationship between ventricular contractility and afterload. We sought to determine the relationship between ventricular-arterial coupling and right ventricular (RV) remodeling in a novel porcine model of progressive pulmonary hypertension (PH). Chronic PH was induced in pigs by ligation of the left pulmonary artery ...
Mishra Amit A U.N. Mehta Institute of Cardiology and Research Center, Asarwa, Ahmedabad, India - - 2013
Total anomalous systemic and pulmonary venous connection is an extremely rare congenital cardiac anomaly. We present our unique experience of managing this complex partially diagnosed cardiac anomaly in a 16-month-old boy. The systemic venous anomaly was not detected during the initial preoperative evaluation. He was doing well on follow-up, with ...
Cheng Allen - - 2013
Sinus of Valsalva aneurysm (SVA) is a rare cardiac lesion especially in the western countries and older population. We report an unusual case of a 60-year-old Caucasian male with SVA, acute decompensation, and a pressurized prolapsed aortic leaflet cystic remnant via a small supracristal VSD causing recurrent right ventricular outflow ...
Konik Ewa A - - 2013
Pulmonary arterial hypertension (PAH) is associated with refractory vasoconstriction and impaired NO-mediated vasodilatation of the pulmonary vasculature. Vascular tone is regulated by light chain (LC) phosphorylation of both nonmuscle (NM) and smooth muscle (SM) myosin, which are determined by the activities of MLC kinase and MLC phosphatase. Further, NO mediated ...
Yokoyama Utako - - 2013
Elastic fiber formation begins in mid-gestation and increases dramatically during the last trimester in the great arteries, providing elasticity and thus preventing vascular wall structure collapse. However, the ductus arteriosus (DA), a fetal bypass artery between the aorta and pulmonary artery, exhibits lower levels of elastic fiber formation, which promotes ...
Stoyanov Nik - - 2013
A 51-year-old lady presented with increasing heart failure symptoms and palpitations. She had recently been diagnosed with a congenital ventricular septal defect, bicuspid aortic valve, and Eisenmenger's syndrome. There was clinical evidence of right heart failure and differential clubbing and cyanosis affecting the feet but not hands. A cardiac magnetic ...
Zhou Jinxing - - 2013
This study aims to systematically investigate intrapulmonary artery segmentation, blood vessel wall characteristics and structure organization, and the interrelation between intrapulmonary artery structure and plateau hypoxia adaptation in yak. The normal intrapulmonary artery structure of the yak had been studied using histological methods and transmission electron microscopy. The intrapulmonary artery ...
Kadirvel Ramanathan - - 2013
Purpose:To characterize the progression of healing across aneurysm necks following treatment with a flow diverter in a rabbit aneurysm model.Materials and Methods:With institutional animal care and use committee approval, saccular aneurysms were created in 20 rabbits and treated with flow diverters. On days 1, 3, and 7 and weeks 4 ...
Ozawa Yuichiro - - 2013
We present a case of cardiac tamponade after lung resection. A 68-year-old man underwent single-staged bilateral lung resection (right wedge resection and left S8 segmentectomy) for metastatic lung tumors from rectal cancer and lost consciousness on postoperative day 4. Because an enhanced whole-body computed tomography scan showed pericardial effusion as ...
Meisner Joshua K - - 2013
Adaptive vascular remodeling in response to arterial occlusion takes the form of capillary growth (angiogenesis) and outward remodeling of pre-existing collateral arteries (arteriogenesis). However, the relative contributions of angiogenesis and arteriogenesis toward the overall reperfusion response are both highly debated and poorly understood. Here, we tested the hypothesis that myoglobin ...
Garat Chrystelle V - - 2013
Hypoxia-induced pulmonary hypertension (PH) is characterized by progressive remodeling of the pulmonary artery (PA) system, and loss of the transcription factor CREB in PA smooth muscle cells (SMCs). Previous in vitro studies suggested that PDGF, a mitogen produced in the hypoxic arterial wall, elicits loss of CREB in medial SMCs ...
O'Neill W Charles - - 2013
The pathophysiology of medial arterial calcification in chronic kidney disease (CKD) is unclear but has been ascribed to phenotypic changes in vascular smooth muscle, possibly in conjunction with intimal proliferation and atherosclerosis. As the prevalence of calcification in breast arteries is increased in women with CKD and end-stage renal disease ...
Riches Kirsten - - 2013
Vascular smooth muscle cells (SMC) are central to arterial structure and function yet their involvement in the progression of abdominal aortic aneurysm (AAA) disease is not well studied. The progressive and silent nature of AAA in man essentially restricts research to the use of "end-stage" tissue recovered during surgical repair. ...
Petersen Karin Kastberg - - 2013
The high pressure in giraffe leg arteries renders them vulnerable to edema. We investigated whether large and small arteries in the legs and the tight fascia protect leg capillaries. Ultrasound imaging of foreleg arteries in anesthetized giraffes and ex vivo examination revealed abrupt thickening of the arterial wall and a ...
Corrado Giovanni - - 2013
A 63-year-old woman was admitted because of sudden ischemic hemyplegia promptly cleared up by intravenous (IV) recombinant tissue plasminogen activator. On subsequent 2-dimensional echocardiogram, we observed an extremely mobile homogeneous mass attached by a short stalk to ventricular insertion of anterolateral papillary muscle chordae tendineae. The mass was surgically removed. ...
Bashir Ahmed - - 2013
Temporary epicardial pacing wires (TEPWs) are commonly used during cardiac surgery to meet unforeseen complications like heart blocks or asystole. These are generally considered to be safe. The incidence of major complications with their use is low, but could be life threatening. Complications can be divided into those encountered during ...
Vihlen Christopher - - 2013
We present the case of a 6-month-old infant born premature at 29 weeks with perinatal stroke and postnatal hypoxia. Echocardiogram was suspicious for partial anomalous pulmonary venous return (PAPVR). Cardiac CT showed an unusual variant of PAPVR, with a vertical vein having a dual connection superiorly to the left innominate ...
Negi Smita I - - 2013
Aortic annular rupture is a rare and much dreaded complication of transcatheter aortic valve replacement. Device oversizing to prevent post-procedural paravalvular leak is the most commonly identified cause of this complication. However, mechanical stress in a heavily calcified non-compliant vessel can also lead to annular rupture in this older population. ...
Dilber Daniel - - 2013
Although closure of an atrial septal defect (ASD II) with an occluding device in the first year of life is not a routine procedure, it is a feasible treatment, even in neonates. Case reports on the off-label use of Amplatzer devices have been repeatedly published, but there are no reports ...
Kavarana Minoo N MN Division of Cardiothoracic Surgery, Medical University of South Carolina, Charleston, South Carolina. Electronic address: - - 2013
Longevity of the superior cavopulmonary connection (SCPC) is limited by the development of pulmonary arteriovenous malformations (PAVM). The goal of this study was to determine whether phenotypic changes in pulmonary artery endothelial cells (PAEC) that favor angiogenesis occur with PAVM formation. A superior vena cava to right pulmonary artery connection ...
Speelman Jonathan Paul - - 2013
ABSTRACT Background: A novel live porcine model replicated the endoscopic surgical field of a carotid arterial injury of the human skull base. Hemostatic techniques were applied to jugular venous and carotid arterial injuries, including muscle patches, hemoclips, and aneurysm clips. Doppler imaging distal to the injury assessed flow through the ...
Daignault Michael C - - 2013
Thoracic aortic aneurysms (TAAs) are less prevalent than abdominal aortic aneurysms. Symptomatic TAAs need to be identified quickly by the emergency physician (EP) since mortality rates increase dramatically once complications such as rupture or dissection occur. Compared with validated EP-performed ultrasound of the abdominal aorta, EP-performed focused cardiac ultrasound that ...
Kim Ki-Sung - - 2013
Endothelin-1 (Edn1), originally identified as a vasoconstrictor peptide, is involved in the development of cranial/cardiac neural crest-derived tissues and organs. In craniofacial development, Edn1 binds to Endothelin type-A receptor (Ednra) to induce homeobox genes Dlx5/Dlx6 and determines the mandibular identity in the first pharyngeal arch. However, it remains unsolved whether ...
Meredith Graham T - - 2013
Adipose tissue is a normal constituent of the heart, but not a normal anatomic finding of cardiac valves. Fatty infiltration of the aortic valve is rare, with unknown significance on valve function. We report a case of fatty infiltration and replacement of the spongiosa layer in an incompetent aortic valve. ...
Kang Ning - - 2013
Anomalous coronary arteries are rare but can lead to serious complications during cardiac operations if not recognized. We report a 55-year-old woman with anomalous origin of the right coronary artery from the left ventricle, and bicuspid aortic valve stenosis. Coronary angiography and computerized tomographic angiography indicated the diagnosis preoperatively. She ...
Guo Dong-chuan DC Department of Internal Medicine, University of Texas Health Science Center at Houston, Houston, TX 77030, - - 2013
Gene mutations that lead to decreased contraction of vascular smooth-muscle cells (SMCs) can cause inherited thoracic aortic aneurysms and dissections. Exome sequencing of distant relatives affected by thoracic aortic disease and subsequent Sanger sequencing of additional probands with familial thoracic aortic disease identified the same rare variant, PRKG1 c.530G>A (p.Arg177Gln), ...
Verma Suman - - 2013
Maxillary artery is one of the key contents of the infratemporal fossa. Mandibular nerve and its branches form a clinically important relation of maxillary artery in this region. A comprehensive knowledge of variations of maxillary artery in the fossa is of special relevance in oral maxillofacial surgeries, management of epistaxis, ...
Bishnoi Ram N - - 2013
A left coronary artery arising from the right sinus of Valsalva is a rare congenital coronary anomaly. We report a case of a 5-year-old boy with an anomalous left coronary artery from the right sinus of Valsalva whose presenting sign was cardiac arrest. There is no reported instance of a ...
Li Yue - - 2013
Coronary artery bypass grafting (CABG) is among the most commonly performed heart surgical procedures. Saphenous vein graft failure due to stenosis impedes the longer-term success of CABG. A key cellular event in the process of vein graft stenosis is smooth muscle cell hyperplasia. In this study, we evaluated the effect ...
Peng Tien T Department of Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania 19104, - - 2013
Co-development of the cardiovascular and pulmonary systems is a recent evolutionary adaption to terrestrial life that couples cardiac output with the gas exchange function of the lung. Here we show that the murine pulmonary vasculature develops even in the absence of lung development. We have identified a population of multipotent ...
Gillis Elisabeth - - 2013
Aortic aneurysm, including both abdominal aortic aneurysm and thoracic aortic aneurysm, is the cause of death of 1% to 2% of the Western population. This review focuses only on thoracic aortic aneurysms and dissections. During the past decade, the genetic contribution to the pathogenesis of thoracic aortic aneurysms and dissections ...
Pan Jun - - 2013
We describe a case with left atrial volume reduction of a giant left atrium, treated successfully by partial cardiac autotransplantation, concomitant mitral and aortic valve replacement, and tricuspid valve plasty. We obtained good results at the 1-year follow-up.
Jeong Hee-Jin - - 2013
In the α1,3-galactosyltransferase knockout (α-GalT KO) pig era, identification of the non-Gal epitopes is necessary for successful pig-to-human xenotransplantation. Recently, we successfully detected α-Gal epitopes as well as Hanganutziu-Deicher (H-D) antigens from the N-glycans in the pig heart tissues, which have been considered as promising non-Gal antigens. However, the profiling ...
Young Aisha N - - 2013
The vervet monkey (Chlorocebus sabaeus) is used commonly in cardiorespiratory biomedical research. This study was performed to establish reference values for thoracic structures and to describe the normal radiographic appearance of the vervet monkey thorax. Right lateral and dorsoventral thoracic radiographs of ten mature vervet monkeys were evaluated. Anatomic structures ...
Ito Masaki - - 2013
Although the healing response after carotid balloon injury and carotid patch angioplasty injury has been well-documented in animal models, there is limited information about this process following carotid endarterectomy (CEA) in human patients. Here, we describe the autopsy results of a 79-year-old man who died 18 days after CEA with ...
Galoin-Bertail Claire - - 2013
Cor triatriatum sinister is an uncommon congenital cardiac anomaly accounting for 0.1% of all congenital cardiac malformations, with an anomalous venous return being a frequently associated condition. We present the case of a 14-year-old girl misdiagnosed as having an atrial septal defect with pulmonary hypertension who actually had a cor ...
Fairfax Seth T - - 2013
Large increases in muscle sympathetic nerve activity (MSNA) can decrease the diameter of a conduit artery even in the presence of elevated blood pressure, suggesting that MSNA acts to regulate conduit artery tone. Whether this influence can be extrapolated to spontaneously occurring MSNA bursts has not been examined. Therefore, we ...
Schwartz P - - 2013
Under certain circumstances, the placement of arterial catheters can be difficult. In these instances, a form of guidance is preferred to avoid repeated insertions of the arterial catheter. Ultrasonic guidance is generally used in these instances, but the equipment required is expensive and cumbersome. This study produced an arterial catheter ...
Tarui Tatsuya T Department of Cardiovascular Surgery, Toyama Red Cross Hospital, Toyama City, - - 2013
A 67-year-old man was admitted with right ventricular free wall rupture secondary to occlusion of the left anterior descending artery. Emergency coronary angiography showed total occlusion of the proximal left anterior descending artery and severe stenosis of the proximal right coronary artery. Echocardiography revealed acute cardiac tamponade, and free wall ...
Brock Michael M Department of Pediatrics, Arnold Palmer Hospital for Children, Orlando, Florida, - - 2013
A quadricuspid aortic valve is rarely diagnosed in children, but it can be associated with significant aortic regurgitation. It is important for pediatric cardiologists to be aware of this pathologic entity. We present a nine-year-old male, diagnosed with a quadricuspid aortic valve and mild aortic regurgitation.
Pamukcu Ozge O Erciyes University School of Medicine, Division of Pediatric Cardiology, Kayseri, - - 2013
We report a newborn with an unusual combination of aneurysmally dilated thin-walled right ventricle with hypertrophy of the apical muscles of the right ventricle. There was narrow pulmonary annulus, pulmonary regurgitation, and hypoplasia of the mitral valve and left ventricle. We propose that this heart represents a partial form of ...
Sapre Ashish A Department of Pediatric Cardiology, Amrita Institute of Medical Sciences and Research Centre, Cochin, Kerala, - - 2013
Double-orifice tricuspid valve (DOTV) is a very rare congenital cardiac anomaly. We report an unusual example of DOTV where one orifice was committed to the left ventricle. This was identified preoperatively and managed surgically.
Baspinar Osman O Department of Pediatric Cardiology, Gaziantep University Medical Faculty, Gaziantep, - - 2013
The internal jugular vein is not a typical vascular access line during the percutaneous closure of an atrial septal defect. We report the closure of a double atrial septal defect with a single device, using a transjugular venous approach, in a child with an inferior vena cava obstructed by a ...
Sirasanagandla Srinivasa Rao - - 2013
Accessory liver lobe is found incidentally during laparoscopy, laparotomy or autopsy performed for unrelated reasons. The occurrence of accessory liver lobe attached to the gallbladder is reported rarely in the literature. During regular dissection classes, we came across an accessory liver lobe in the wall of the gallbladder in an ...
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