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Zamboni Giulia A - - 2011
OBJECTIVE: To test a low dose, low voltage protocol for the diagnosis of pulmonary embolism. MATERIALS AND METHODS: 50 Patients with clinically suspected pulmonary embolism underwent CTPA with 80kVp and 295mAs (test group) on a 64-row MDCT scanner. These patients were compared to a similar group of 50 patients scanned ...
Yamada Kiyofumi - - 2011
Background: A major concern with carotid artery stenting (CAS) is the potential for cerebral embolism. The purpose of this study was to determine whether virtual histology intravascular ultrasound (VH-IVUS) can predict the risk of a silent ischemic lesion after CAS. Methods: We performed CAS in 45 patients with carotid stenosis. ...
Zeng Wei-Jie - - 2011
BACKGROUND: The difference in underlying pathophysiology in different congenital heart disease (CHD) may have an influence on clinical outcome. It remains unclear whether the effect of sildenafil on pulmonary arterial hypertension (PAH) varies in different types of CHD. HYPOTHESIS: The potential effect of sildenafil on pulmonary arterial hypertension related to ...
Gan Hui-Li - - 2011
BACKGROUND: Our aim was to determine whether general left main coronary artery stenosis (LMS) and ostial LMS pose additional risks after off-pump coronary artery bypass grafting (CABG) relative to non-left main coronary artery stenosis. METHODS: From January 1, 2008, to December 31, 2009, 4366 patients underwent primary isolated off-pump CABG ...
Dang Sha - - 2011
The neuroprotective effect of erythropoietin has been demonstrated by ischemia and reperfusion models in adult and neonatal rodents. However, administration of high-dose erythropoietin has potential complications. The goal of this study was to determine whether local infusion of low dose erythropoietin offers neuroprotective effects after ischemia and reperfusion injury. Adult ...
Nakatamari Hazuki - - 2011
PURPOSE: To determine the association of native thoracic aortic curvature measured from computed tomographic (CT) angiography categorized by discriminant analysis with the development of endoleaks after thoracic endovascular aortic repair (EVAR). MATERIALS AND METHODS: Forty patients (28 men, 12 women; mean age, 74 y; range, 40-89 y) with aortic diseases ...
Yıldırım Engin - - 2011
OBJECTIVE: Although estrogens have been shown to be vasoactive hormones, the vascular effects of testosterone are not well defined. Little is known about the in vitro effects of testosterone on isolated arteries. The purpose of this experimental prospective study was to assess the direct effect of testosterone on isolated sheep ...
Kanchi Muralidhar - - 2011
Endotracheal intubation involving conventional laryngoscopy elicits a haemodynamic response associated with increased heart and blood pressure. The study was aimed to see if video laryngoscopy and endotracheal intubation has any advantages over conventional laryngoscopy and endotracheal intubation in patients with coronary artery disease. Thirty patients suffering from coronary artery disease ...
Lim Kyung Seob - - 2011
The aim of this study was to examine the anti-proliferative and anti-inflammatory effects of a stent coated with abciximab and alpha-lipoic acid (ALA) in a porcine coronary overstretch restenosis model. A total of 10 pigs were randomized into two groups (10 pigs, 10 coronaries in each group) in which the ...
Pozzi-Mucelli F - - 2011
PURPOSE: This study reviews our experience over the last 10 years with procedures of embolisation and/or exclusion of the renal arteries, their parenchymal branches and the polar arteries [renal artery embolisation (RAE)]. MATERIALS AND METHODS: Twenty-seven patients (19 men and eight women; age range 37-93 years; mean 74 years) underwent ...
Kim Sung Hoon - - 2011
This study was designed to evaluate the effect of portal vein embolization on liver regeneration after major liver resection. A retrospective analysis was performed on 24 patients who underwent extended hepatectomy for hilar cholangicellular carcinoma between 2001 and 2008. Eleven patients underwent portal vein embolization and 13 did not. Computed ...
Tan I Y L - - 2011
The aim of this study was to retrospectively assess the recanalization rate, factors associated with and time taken for recanalization to occur in a matched ruptured and unruptured aneurysm population that were treated with endovascular coiling.Ruptured and unruptured aneurysms treated between 2002 and 2007 were matched for aneurysm location, diameter ...
Nakata Kinichi - - 2011
The aim of this study was to evaluate a new flow analyze device that can intraoperatively measure compliance and resistance of coronary artery bypass grafting (CABG) by the parameter identification method. Subjects were 95 patients who underwent CABG. Angiography soon after surgery confirmed patency in 90 grafts and graft failure ...
Abizaid Alexandre - - 2011
At present, percutaneous coronary intervention with drug-eluting stent (DES) implantation represents the default strategy to treat coronary artery disease in many institutions around the world. However, concerns regarding long-term safety of first-generation DES have prompted the development of novel DES systems such as the NEVO (Cordis Corporation, Johnson & Johnson, ...
Zong Gang-Jun - - 2011
In recent years, some experimental and clinical studies on transcatheter aortic valve implantation (TAVI) have been conducted. TAVI is indicated in patients with calcified pure or predominant aortic stenosis. The risk of this technique is still high. Aortic valved stent implantation above the coronary ostia might avoid blocking the coronary ...
Sung Jiyoon - - 2011
Coronary artery plaque is related to development of coronary artery disease (CAD), and chronic kidney disease is associated with CAD. However, the association of renal dysfunction (RD) with coronary artery plaque characteristics has not been fully elucidated. We evaluated the association between RD and coronary artery plaque characteristics in patients ...
Hirata Yoichiro - - 2011
It has been hypothesized that epicardial fat, a local visceral fat depot with close proximity to coronary arteries, may serve as a source of inflammatory cytokines and cells in coronary atherosclerotic lesions. Here, we characterized infiltration of inflammatory cells and expression of adipocytokines in epicardial adipose tissue in patients with ...
Duan Wei - - 2011
To investigate how cognitive impairment is affected by the relief of bilateral carotid stenosis, chronic cerebral hypoperfusion was established through stenosis of the bilateral carotid common artery in adult Sprague-Dawley rats. Subsequently, the model rats received the intragastric placebo, donepezil (5 mg per kg), or surgery to relieve carotid stenosis ...
Shen L - - 2011
Objective: To investigate the relationship between the pulse wave velocity (PWV) and angiographic carotid atherosclerosis in elderly patients. Method: 103 consecutive elderly patients were divided into two groups according to the results of cerebral angiography: carotid atherosclerosis group and normal carotid angiogram group. Basic clinical information was required by a ...
Argiriou Mihalis - - 2011
In right ventricular failure (RVF), an interatrial shunt can relieve symptoms of severe pulmonary hypertension by reducing right ventricular preload and increasing systemic flow. Using a pig model to determine if a pulmonary artery-left atrium shunt (PA-LA) is better than a right atrial-left atrial shunt (RA-LA), we compared the hemodynamic ...
Schmidt Andrej - - 2010
Restenosis-rate after balloon-angioplasty of long segment tibial arterial disease is largely unknown. We investigated the restenosis-rates angiographically in patients with critical limb ischemia (CLI) due to extensive infrapopliteal lesions. Angioplasty for infrapopliteal lesions exclusively ≥80 mm in length was performed using dedicated 80-120 mm long low-profile balloons. Follow-up included angiography ...
Counsell Andrew - - 2011
Restenosis after carotid endarterectomy (CEA) has been described in 8-19% of patients, 14-23% of whom become symptomatic. This study analyzes our experience with carotid artery stenting (CAS) for post-CEA recurrent stenoses. Retrospective database and case-note review. Between January 2000 and September 2008, a total of 27 patients (15 symptomatic) with ...
Banerjee S - - 2010
Drug eluting stents (DES) have improved percutaneous coronary intervention (PCI) outcomes for most coronary lesion subsets and have gained widespread acceptance. This practice is supported by large-scale clinical trials. Evidence for DES use for treatment of saphenous vein graft (SVG) lesions is less well defined and often conflicting. Most SVG ...
Thai Wai-Ee - - 2010
An increasing number of patients undergo left main stenting as an alternative to coronary artery bypass graft surgery (CABGS). Post procedure surveillance with invasive angiography is common practice to detect in-stent restenosis (ISR) which can result in fatal myocardial infarction and even sudden death. There is currently no consensus as ...
Kaichi Shinji - - 2011
Drug-eluting stents (DES) have markedly reduced the incidence of coronary in-stent restenosis. However, DES may be still vulnerable to coronary thrombus, and the long-term outcome remains unknown, especially in infancy. Here, we present a 9-month-old infant, who developed severe stenosis of the left main coronary artery after surgery for Brand-White-Garland ...
Raja Yogesh - - 2011
Iatrogenic stenosis of the coronary ostia is a rare but life-threatening complication which may follow aortic valve replacement. We report a case treated with a drug-eluting stent with subsequent severe restenosis at 24months. In-stent restenosis was successfully treated with reimplantation of a further drug-eluting stent with no restenosis on surveillance ...
Yang W-J - - 2011
This study compared the performance of prospectively electrocardiographically (ECG)-triggered axial computed tomography (CT) angiography with retrospective technique in evaluating coronary artery stent restenosis by 64-slice CT. A pulsing cardiac phantom with artificial coronary artery in-stent restenosis was examined by CT angiography with different types of scan modes. The visibility of ...
Tomasevic M - - 2010
Coronary artery bifurcations are one of the largest challenges in interventional cardiology. Presented is the case of a patient in whom restenosis of a drug-eluting stent (DES) occurred as a consequence of guide wire re-crossing between the main vessel stent struts and the vessel wall in the proximal part of ...
Yamagami Hiroshi - - 2012
Restenosis after carotid artery stenting (CAS) is a critical issue. Cilostazol can reduce restenosis after interventions in coronary or femoropopliteal arteries. We investigated whether periprocedural cilostazol treatment was related to the incidence of in-stent restenosis (ISR) or target vessel revascularization (TVR) after CAS. The study group comprised 553 of 580 ...
Eshtehardi Parham - - 2010
We investigated the impact of arterial injury on neointimal hyperplasia following implantation of drug-eluting stents (DES). A total of 196 patients with 223 segments (sirolimus-eluting stents [SES]: 104, paclitaxel-eluting stents [PES]: 119) underwent intravascular ultrasound eight months after DES implantation. Arterial injury was defined as the balloon-to-artery ratio (BAR). Segments ...
Brilakis Emmanouil S - - 2010
We report two cases of flush chronic total occlusion due to in-stent restenosis, in which percutaneous coronary intervention attempts via over-the-wire balloons and microcatheters failed to cross the lesion. Using the Venture catheter for support and the Stingray guidewire for enhanced penetration capacity, both lesions were successfully crossed and stented.
Zhou Xu-chen - - 2010
Coronary artery in-stent restenosis (ISR) and late stent thrombosis remain as important complications of stenting. The inflammation reactions to sirolimus and paclitaxel-eluting stents were investigated in a swine stenosis model induced by interleukin (IL)-1β. Mini pigs (n = 12; 2-3 months old and weighing 25-30 kg) were subjected to thoracotomy. ...
Ito Hiroki - - 2010
Smaller coronary arteries are less able to accommodate late loss after percutaneous coronary interventions than larger arteries. The first-generation drug-eluting stents have been shown to have better control of neo-intimal hyperplasia and lower late lumen loss compared with bare-metal stents. However, the reported rates of binary restenosis are still unsatisfactory ...
Claessen B E - - 2010
Treatment options for coronary revascularisation include percutaneous coronary intervention (PCI) and coronary artery bypass grafting (CABG). In the 'synergy between PCI with TAXUS and cardiac surgery (SYNTAX)' trial, PCI and CABG using state-of-the-art techniques (using paclitaxel-eluting stents and arterial grafts, respectively) were compared in the treatment of complex coronary artery ...
Dʼamico Maurizio - - 2010
Coronary stent fracture is a relatively rare but potentially serious complication of coronary artery stenting, in particular with sirolimus-eluting stents. It has been recognized as one possible cause of in-stent restenosis as well as acute stent thrombosis. The formation of coronary artery aneurysm is one of the critical complications after ...
Manzi M - - 2010
In the last years the development of new techniques and technologies for the endovascular treatment of peripheral arterial occlusive disease has allowed to treat a vast array of lesions with high technical success and low complications. Despite these advances, restenosis, and in particular in-stent restenosis, is a problem that significantly ...
Kwa A T - - 2010
Restenosis rates in the superficial femoral artery remain high in patients treated with balloon angioplasty or bare metal stents. Stent-grafts represent an alternative endovascular treatment modality for these patients. In the US, the only FDA-approved stent-graft for femoral use is the Viabahn endoprosthesis (W.L. Gore, Flagstaff, AZ). The Viabahn is ...
Nguyen Thach - - 2010
The concept of coronary angioplasty percutaneous coronary intervention (PCI) was pioneered by Andreas Gruntzig. Since then, several modifications, innovative devices, techniques, and advances have revolutionized the practice of interventional cardiology. Coronary bifurcation and chronic total occlusion are the last two frontiers that continue to challenge the skills of the interventional ...
Zeller T - - 2010
In-stent restenosis (ISR) after non-coronary interventions is becoming an increasing clinical and technical problem in daily practice due to the more liberal use of stents particularly in femoro-popliteal and infra-popliteal interventions. Whereas in the coronaries the role of drug eluting stents (DES) in the treatment of ISR is already well ...
Murasato Yoshinobu - - 2010
The treatment of coronary bifurcation lesion remains a challenging issue even in the drug-eluting stent era. Frequent restenosis and stent thrombosis have been recently shown to be related not only to geometrical gap or stent structural deformation but also to rheological disturbance. Low wall shear stress at the lateral side ...
Miyamoto Yoshinori - - 2010
Coronary flow velocity reserve (CFVR) may reflect coronary microvascular endothelial function in the absence of significant epicardial coronary artery stenosis. The purpose of this study was to evaluate coronary microvascular endothelial function late (6 and 12 months) after sirolimus-eluting stent (SES) implantation using transthoracic Doppler echocardiography. A total of 21 ...
Iaccarino Daniele - - 2010
BACKGROUND: Drug-eluting stents (DES) have been designed to prevent restenosis, but long-term clinical outcome may be offset by an increased risk of stent thrombosis, which is associated with suboptimal stent implantation or delayed re-endothelialization. DES implantation has also been associated with local persistent endothelial dysfunction. Conversely, Trapidil is a potent ...
Garcia Santiago - - 2010
BACKGROUND: The natural history of coronary artery disease (CAD) after vascular surgery is poorly defined. The aim of this study was to determine the temporal change of coronary artery lesions requiring revascularization with a percutaneous coronary intervention (PCI) after elective vascular surgery and to determine the utility of preoperative biomarkers ...
Lahidheb Dhaker - - 2010
BACKGROUND: Angioplasty of coronary arteries with a small diameter (commonly defined as diameter inferior than 2.75 mm) is associated with a high rate of restenosis and revascularization. Since the use of Drug Eluting Stents (DES) and considering their good results on simple lesions compared to other techniques (balloon dilation and ...
Kandzari David E - - 2010
Given statistically significant and clinically meaningful reductions in angiographic restenosis and repeat revascularization, treatment with drug-eluting stents (DESs) has become established as a standard of care in percutaneous coronary revascularization. However, despite their superior efficacy compared with conventional bare metal stents, experiences with first-generation DESs from both clinical trials and ...
van den Heuvel Mieke M Department of Cardiology, Thoraxcenter, Erasmus University Medical Center, Rotterdam, the - - 2010
The aim of this study was to compare the effects of single drug-eluting stents (DES) on porcine coronary function distal to the stent in vivo and in vitro. The mechanism of endothelial dysfunction occurring in human coronary conduit arteries up to 9 months after DES implantation is unknown. A sirolimus-eluting ...
Mueller Goetz Christoph - - 2010
Paclitaxel-eluting balloons are a new and innovative method in the treatment of in-stent stenosis and small vessel disease in adult cardiac pathology. The treatment of congenital pulmonary vein stenosis is difficult to manage, and results in a high mortality rate due to residual or recurrent stenosis. We report the first ...
Wainstein Marco V - - 2010
Two months after left anterior descending (LAD) artery and left circumflex (LCx) artery bare metal stent implantation, a proliferative subocclusive in-stent restenosis in LCx coronary with severe LM coronary (LM) involvement developed. The present clinical case describes a simplified strategy for unprotected LM percutaneous coronary intervention using two bioabsorbable biolimus-eluting ...
Kereiakes Dean J - - 2010
OBJECTIVES: The aim of this study was to evaluate the safety and efficacy of the novel platinum chromium TAXUS Element paclitaxel-eluting stent (PES) compared with the TAXUS Express PES (Boston Scientific, Natick, Massachusetts) in treating coronary artery stenoses. BACKGROUND: The TAXUS Element is a novel thin-strut (81 microm), platinum chromium ...
Furukawa Takeshi - - 2010
The outcome of stent implantation for pulmonary vein stenosis (PVS) in children remains poor. Several reports describe placing drug-eluting stents to treat PVS, but their effectiveness remains unknown. In this study, three bare-metal stents (BMSs) and three sirolimus-eluting stents (SESs) were implanted in 1-month-old pigs. The pigs were killed 8 ...
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