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Results 201 - 250 of 899
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Watanabe Satoshi - - 2011
We report on a 73-year-old man with systemic lymphadenopathy and chest computed tomography (CT) findings of bilateral diffuse ground-glass opacities and interlobular septal thickening. He also had pulmonary arterial hypertension (PAH). Several lymph node biopsies were attempted, without a definitive diagnosis. A thoracoscopic lung biopsy was performed, and the specimen ...
Sabnis Girish R - - 2011
We present the case of a hypertensive male who came with acute onset of severe backache and hypotension. Emergency imaging revealed a penetrating atherosclerotic ulcer of descending thoracic aorta with contained rupture and bilateral hemothorax. Initially stabilised with medical management, this patient went on to undergo endovascular stent-grafting. The sequence ...
Kiefer Todd L - - 2011
Pulmonary hypertension (PH) is the end result of a variety of diverse pathologic processes. The chronic elevation in pulmonary artery pressure often leads to right ventricular pressure overload and subsequent right ventricular failure. In patients with left-sided cardiac disease, PH is quite common and associated with increased morbidity and mortality. ...
Hernández-Rivera Helder - - 2011
Pulmonary arterial hypertension used to be considered an ultimately fatal disease despite the formerly available therapy. It is a disease characterized by progressive elevation of pulmonary vascular resistance and pulmonary arterial pressure, eventually resulting in right ventricular failure and death. The purpose of this article is to review the basic ...
Vachev A N - - 2011
The article deals with surgical treatment of patients presenting with resistant arterial hypertension and detected pathology in the adrenal glands. The authors analysed the outcomes of surgical management of 97 patients with resistant arterial hypertension, also determining the factors contributing to prediction of the antihypertensive effect of adrenalectomy depending on ...
Ivanović Branislava - - 2011
Arterial hypertension is not an independent risk factor in cardiovascular complications in noncardiac surgery. Nevertheless, preoperative evaluation is necessary and includes estimation of arterial hypertension grade and possible damage of target organs. In patients with first and second grade of arterial hypertension postponement of elective intervention is not necessary, only ...
Martinez-Lemus Luis A - - 2011
Inward eutrophic remodeling is a common structural change found in small resistance arteries that has been associated with an increased risk for life threatening cardiovascular events, the number one cause of death in industrialized societies. Because inward eutrophic remodeling is the most prevalent small artery structural change found in hypertension, ...
Goncalvesova E - - 2011
Distinguishing pulmonary arterial hypertension (PAH) and pulmonary hypertension due to left ventricular diastolic dysfunction (PHLDD) is essential for the correct disease management. We compared the importance of electrocardiographic (ECG) signs of right ventricular hypertrophy (RVH) in patients with similar degree PAH and PHLDD. ECG analysis was retrospectively performed in 17 ...
Antsupov K A - - 2011
Described in the article are technical peculiarities of performing eversion carotid endarterectomy with the preservation of the structure of the carotid glomus. Atherosclerosis of the carotid artery bifurcation appears to infl uence the onset and course of arterial hypertension. An important role therein is played by barorefl ex and glomus ...
Fukumoto Yoshihiro - - 2011
Pulmonary hypertension (PH) is a fatal disease caused by small pulmonary artery obstruction from vascular proliferation and remodeling. PH is characterized by elevated pulmonary arterial pressure and increased pulmonary vascular resistance, frequently leading to right-sided heart failure and death. The classification of PH has been recently updated to include 5 ...
Rahnavardi Mohammad - - 2011
Pulmonary thromboendarterectomy (PTE) is a treatment option for patients with chronic thromboembolic pulmonary hypertension (CTEPH). The present systematic review was performed to assess the safety and efficacy of PTE for CTEPH. A systematic review was performed, and six electronic databases were searched for published studies from January 1999 to February ...
Kenny Damien - - 2011
Coarctation of the aorta was once viewed as a simple discrete narrowing of the aortic isthmus that could be 'cured' by surgical intervention. It is now clear that this condition may: (1) affect the aortic arch in a highly variable manner; (2) be associated with a host of other left ...
Mac-Way Fabrice - - 2011
Arterial stiffness is the major determinant of isolated systolic hypertension and increased pulse pressure. Aortic stiffness is also associated with increased cardiovascular morbidity and mortality in patients with chronic kidney disease, hypertension, and general population. Hemodynamically, arterial stiffness results in earlier aortic pulse wave reflection leading to increased cardiac workload ...
Hosokawa Kazuya - - 2011
Pulmonary thromboendarterectomy (PEA) is a curative therapy for chronic thromboembolic pulmonary hypertension (CTEPH), but the postoperative mortality remains unsatisfactory (4-10%). Residual pulmonary hypertension is the most common cause of perioperative death. Although PEA specimens seem to contain lesions responsible for hemodynamic improvement, relevant histopathological findings have still to be identified.The ...
Houtchens Jeanne - - 2011
Pulmonary arterial hypertension is a rare disease, which requires a high index of suspicion to diagnose when patients initially present. Initial symptoms can be nonspecific and include complaints such as fatigue and mild dyspnea. Once the disease is suspected, echocardiography is used to estimate the pulmonary arterial (PA) pressure and ...
Kanabuchi Kazuo - - 2011
We present a case of ischemic optic neuropathy (ION) developed 11 days after an aortic arch replacement in a 59 year-old male who had a history of untreated hypertension. Thoracic CT revealed severe stenosis of the right common carotid artery with poor blood flow. Aortic clamping time was 96 minutes, ...
Kamel Shereen R - - 2011
Pulmonary arterial hypertension (PAH) is a serious and often fatal complication of systemic lupus erythematosus (SLE). Because the diagnosis of PAH often is made years after symptom onset, early diagnostic strategies are essential. Doppler echocardiography currently is considered the noninvasive screening test of choice for evaluating pulmonary hypertension. Screening for ...
Porpodis Konstantinos - - 2011
In recent years, there has been a major advance in the treatment of pulmonary hypertension. New medications are continually added to the therapeutic arsenal. The prostanoids are among the first agents used to treat pulmonary hypertension and are currently considered the most effective. This case study describes a 63-year-old man ...
Natarajan Rajagopalan - - 2011
Pulmonary hypertension is a serious and unrelenting pulmonary vascular disorder that affects the functional quality of patients and significantly decreases their life span. If diagnosed early, with the number of new therapeutic options that are available, a better quality of life can be provided for a protracted length of time. ...
Krenz Elizabeth I - - 2011
A 38-year-old woman with severe pulmonary artery hypertension and a right-to-left shunt of unknown etiology presented at 32 weeks' gestational age. Determination of the cause of her pulmonary hypertension by transesophageal echocardiography was delayed until after delivery secondary to anesthetic risk. She was successfully anesthetized for cesarean delivery using epidural anesthesia. ...
Shimizu Masatoshi - - 2011
Severe pulmonary hypertension in chronic obstructive pulmonary disease (COPD) is referred to as 'disproportionate' because the elevated pulmonary artery pressure does not match the degree of air flow limitation. We report a 41-year-old man presenting with early-onset pulmonary emphysema and pulmonary hypertension with a mean pressure of 74 mmHg. Continuous ...
Ali Omar F - - 2011
Recent clinical data suggest statins have transient but significant effects in patients with pulmonary arterial hypertension. In this study we explored the molecular effects of statins on distal human pulmonary artery smooth muscle cells (PASMCs) and their relevance to proliferation and apoptosis in pulmonary arterial hypertension. Primary distal human PASMCs ...
Courboulin Audrey - - 2011
Pulmonary arterial hypertension (PAH) is a vascular remodeling disease characterized by enhanced proliferation of pulmonary artery smooth muscle cell (PASMC) and suppressed apoptosis. This phenotype has been associated with the upregulation of the oncoprotein survivin promoting mitochondrial membrane potential hyperpolarization (decreasing apoptosis) and the upregulation of growth factor and cytokines ...
Bugan Baris - - 2011
Interrupted aortic arch, characterized by luminal and anatomic discontinuity between the ascending and descending aorta, is a very rare congenital malformation. The condition is typically diagnosed in neonates and is highly fatal if left untreated. Herein, we report the unusual diagnosis of an isolated type A interrupted aortic arch in ...
Araújo Inês - - 2011
Pulmonary artery aneurysms are a rare condition, frequently associated with pulmonary hypertension. However, the evolution and treatment of this pathology is still not clear. The authors report a case of a 65-year old patient with pulmonary artery aneurysm associated with pulmonary arterial hypertension. Due to a positive vasoreactivity test, treatment ...
Denton Christopher P - - 2011
Pulmonary arterial hypertension (PAH) is a serious complication of systemic sclerosis (SSc). In clinical trials PAH-SSc has been grouped with other forms, including idiopathic PAH. The primary endpoint for most pivotal studies was improvement in exercise capacity. However, composite clinical endpoints that better reflect long-term outcome may be more meaningful. ...
Yu Lunyin - - 2011
Hypoxia results in pulmonary hypertension and vascular remodeling due to induction of pulmonary artery cell proliferation. Besides pulmonary artery smooth muscle cells, pulmonary artery endothelial cells (PAECs) are also involved in the development of pulmonary hypertension, but the effect of hypoxia on PAEC proliferation has not been completely understood. We ...
Palma Gaetano - - 2011
Pulmonary hypertension associated with pediatric congenital heart defects is a major cause of postoperative morbidity and death. Sildenafil has been combined with inhaled nitric oxide to treat pulmonary hypertension. We retrospectively studied the pre- and postoperative effects of oral sildenafil as monotherapy in children with pulmonary hypertension who underwent surgery ...
Nguyen Tung H - - 2011
A 51-year-old female undergoing an outpatient stress echocardiogram to evaluate atypical chest pain developed acute ST elevation in the anterior precordial leads on electrocardiogram following exercise. Echocardiography revealed a severe rise in pulmonary artery systolic pressure (PASP) with marked right ventricular (RV) enlargement and interventricular septum flattening. Subsequently, cardiac catherization ...
Kumar Bhupesh B Department of Anesthesia & Intensive Care, Postgraduate Institute of Medical Education and Research, Chandigarh, - - 2011
Although mild increase in pulmonary vascular resistance following intracardiac repair of tetralogy of Fallot is often seen in the early postoperative period, it usually subsides without any sequel. Persistent severe pulmonary artery hypertension after total correction is rare. We report a child with tetralogy of Fallot and Down's syndrome, who ...
Li Ronny X - - 2011
Numerous studies have identified arterial stiffening as a strong indicator of cardiovascular pathologies such as hypertension and abdominal aortic aneurysm (AAA). Pulse Wave Imaging (PWI) is a novel, noninvasive ultrasound-based method to quantify regional arterial stiffness by measuring the velocity of the pulse wave that propagates along arterial walls after ...
Olin James J Department of Pediatrics, University of Colorado, Aurora, Colorado, - - 2011
The authors discuss the case of a 7-year-old female who presented with exertional cyanosis and was found to have pulmonary arterial hypertension. Despite normal left-sided heart function, the patient developed pulmonary oedema in response to pulmonary vasodilator therapy, increasing suspicion for pathology in the pulmonary capillaries and veins. Lung biopsy ...
Sehgal Pravin B PB Departments of Cell Biology & Anatomy, New York Medical College, Valhalla, New York, - - 2011
Earlier electron microscopic data had shown that a hallmark of the vascular remodeling in pulmonary arterial hypertension (PAH) in man and experimental models includes enlarged vacuolated endothelial and smooth muscle cells with increased endoplasmic reticulum and Golgi stacks in pulmonary arterial lesions. In cell culture and in vivo experiments in ...
Park Chan B - - 2011
Bicuspid aortic valve is frequently associated with underlying aortopathy. Data support an aggressive approach to replacement of the ascending aorta. However, the natural history of the unreplaced aortic arch is unknown, and some have advocated routine replacement of the proximal arch in this setting. We identified patients with bicuspid aortic ...
Quintini Cristiano - - 2011
The authors describe a case of a 34-year-old woman who presented to the ER with acute epigastric pain caused by an 8-cm celiac artery aneurysm. The patient underwent total aneurysmectomy, distal splenopancreasectomy, and reconstruction of the hepatic arterial inflow using a fresh cadaveric iliac artery homograft. The patient was discharged ...
Ishizaka Toru - - 2010
We present a new, less-invasive technique for a re-do for perivalvular leakage after aortic mechanical valve replacement. Only the carbon ring of the previously implanted St. Jude prosthesis was excised, the sewing cuff being preserved. The locations of the perivalvular defects were clearly identified by pulling the sewing cuff inward. ...
Thomas Martyn M Cardiovascular Services, Guys and St. Thomas’ Hospital, London, UK. - - 2010
Transcatheter aortic valve replacement is now a viable option in the treatment of high-risk severe symptomatic aortic stenosis. This review describes the current data with this technology and also the potential for the future role of the technology, including potential ways to yet further improve the short- and longer-term results.
Williams Aparna - - 2010
Central venous cannulations are commonly performed in the intensive care unit. However, these may be associated with severe mechanical or bleeding complications. Here, we describe a patient who died following severe and rapid airway obstruction secondary to an arterial trauma during internal jugular vein cannulation. This case report highlights the ...
Stanger Olaf - - 2010
Aortic interposition grafting combined with aortic root replacement (conduit) is widely performed to manage thoracic aortic aneurysms. Intravascular hemolysis without clinical significance is occasionally observed as a complication after prosthetic valve replacement. Symptomatic lysis of red blood cells (RBCs) is rare and primarily attributed to mechanical damage as result of ...
Galvin Sean D - - 2010
Pseudoaneurysm formation at the site of aortotomy is a rare complication following aortic valve replacement; it appears to be more common in those whose valve is replaced for endocarditis or in those who develop an early postoperative endocarditis or sepsis. We discuss the case of a 77-year-old male, who presented ...
Teis Albert - - 2010
Surgicel is bio-absorbable cellulose used to control bleeding. A 52-year-old woman with severe aortic valve regurgitation and aortic dilatation underwent the Ross procedure and ascending aortic replacement. After 48 h, she suffered severe hypotension and hypoxemia. Arteriography revealed stenosis of the pulmonary homograft, which required urgent re-intervention. Extrinsic compression of ...
Gutierrez-Martin Maria A - - 2010
There is a lack of published information about intraoperative and postoperative course of cardiac surgery in patients with essential thrombocytosis using cardiopulmonary bypass. Both risks of intraoperative thrombosis of extracorporeal conduits or uncontrolled postoperative bleeding are present, but its incidence and treatment are not well known. Here, we present a ...
Deorsola Luca - - 2010
Pulmonary valve replacement is rarely performed and is usually done with biological prostheses or grafts. The use of mechanical prostheses is still a debated issue. We analyzed the outcome of 4 patients at 11 years after pulmonary valve replacement with a mechanical prosthesis. During follow-up, all patients remained asymptomatic, with ...
Shibata Toshihiko - - 2010
When a stented bioprosthetic valve is used for aortic valve replacement, the valve stents protruding to the aortic side can interfere with suture tying. To resolve this problem, we developed a novel knot pusher for use on the index finger. This device has a short push rod appropriate for replacing ...
Chan Vincent - - 2010
Long-term thromboembolic and hemorrhagic outcomes after mechanical valve replacement have been well described; however, few studies have described these outcomes after valve replacement with the On-X mechanical prosthesis (On-X Life Technologies, Inc, Austin, Tex). Between 2003 and 2008, 737 patients underwent either aortic valve replacement (n = 400), mitral valve replacement (n = 282), ...
LaPar Damien J DJ Division of Thoracic and Cardiovascular Surgery, Department of Surgery, University of Virginia, Charlottesville, VA 22908-0679, - - 2011
The use of pledgeted sutures to secure the prosthetic valve to the annulus during aortic valve replacement is thought to decrease the incidence of paravalvular leak. We hypothesized that use of nonpledgeted sutures in aortic valve replacement would provide equivalent outcomes to those of a pledgeted suture technique. Between January ...
Curi-Curi Pedro - - 2010
BACKGROUND: Repair of truncus arteriosus communis (TAC) in the neonatal and early infant period has become a standard practice. We report our experience on primary repair of TAC with a bovine pericardial-valved woven Dacron conduit as an alternative procedure to homografts, with a focus on early and midterm results. METHODS: ...
Jashari R - - 2010
European Homograft Bank (EHB) has been selecting, preparing, storing and distributing the cryopreserved allograft valves in Belgium and some other European Countries since 1989. It was established in 1988 by a pathologist and the cardiac and vascular surgeons from Belgian and other European centres as an inter-university, international nonprofit association. ...
Singham S - - 2010
Entrapment of renal artery by the diaphragmatic crus is a rare cause of renal artery stenosis. Spiral computed tomography angiography provides a definitive diagnosis and shows the precise relationship of the artery to the diaphragmatic crus. The authors present a case of hypertension developing in a young 20-year-old female due ...
Badawi Ramy - - 2010
Access closure is the key to successful retrograde percutaneous aortic valve replacement. It requires large-bore femoral arterial access (18-28F) which most operators manage with surgical access and closure under general anesthesia. We report a case example of how, using our center's peripheral interventional experience, we have developed a technique to ...
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