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Nielsen T K TK Department of Anesthesiology and Intensive Care Medicine, Aarhus University Hospital, Aarhus, Denmark; Department of Anesthesiology, Regional Hospital of Randers, Randers, - - 2014
Hemorrhagic shock may trigger an inflammatory response and acute lung injury. The combination adenosine, lidocaine (AL) plus Mg(2+) (ALM) has organ-protective and anti-inflammatory properties with potential benefits in resuscitation.The aims of this study were to investigate: (1) pulmonary function and inflammation after hemorrhagic shock; (2) the effects of ALM/AL on ...
Zhao Zi-Gang ZG Institute of Microcirculation, Hebei North University, Zhangjiakou, - - 2014
To determine the role of mesenteric lymph reperfusion (MLR) on endotoxin translocation in brain to discuss the mechanism of brain injury subjected to superior mesenteric artery occlusion (SMAO) shock. Twenty-four rats were randomly assigned to MLR, SMAO, MLR+SMAO and sham groups. MLR was performed by clamping the mesenteric lymph duct ...
Tamaki Wataru W Department of Pediatric Cardiology, National Cerebral and Cardiovascular Center, Osaka, - - 2014
We describe the case of a 4-year-old boy whose clinical course after Kawasaki disease resulted in coronary artery bypass grafting (CABG) due to acute myocardial infarction (AMI) causing cardiogenic shock. He had developed an ischemic cardiomyopathy due to severe localized stenosis of the left main coronary artery (LCA) and went ...
Shin Beom Soo BS College of Pharmacy, Catholic University of - - 2014
Apicidin is a potential oral chemotherapeutic agent, which possesses potent anti-histone deacetylases activity. Following oral administration, the total bioavailability of apicidin was known to be low (14.2 - 19.3%). In the present study, the factors contributing to the low bioavailability of apicidin were evaluated by quantitative determination of absorption fraction ...
Sufian S S Center for Vein Restoration, Greenbelt, Maryland, - - 2014
To evaluate the incidence of heat-induced thrombosis, its progression and risk factors that may contribute to its formation after endovenous laser ablation. This was a prospective evaluation of all patients who had endovenous laser ablation of the great saphenous vein, accessory saphenous vein, and small saphenous vein using 1470 nm wavelength ...
Carter Howard H HH M408 School of Sports Science, Exercise and Health, The University of Western Australia, 35 Stirling Hwy, Crawley, WA, 6009, Australia, - - 2014
Shear stress is a known stimulus to vascular adaptation in humans. However, it is not known whether thermoregulatory reflex increases in blood flow and shear can induce conduit artery adaptation. Ten healthy young volunteers therefore underwent 8 weeks of 3 × weekly bouts of 30 min lower limb heating (40 °C) during which the upper ...
de Oliveira Góes Junior Adenauer Marinho AM Federal University of São Paulo (UNIFESP-Brazil). Electronic address: - - 2013
To evaluate vascular flow through temporary vascular shunts inserted into peripheral arteries and veins and the repercussion on the arterial perfusion, of venous ligation and venous shunt insertion in an experimental model for damage control. Experimental study in pigs. Animals were distributed in 5 groups: group 1- right external iliac ...
White R N - - 2013
To describe the anatomy of congenital portosystemic shunts emanating from the left gastric vein in dogs and cats. A retrospective review of a consecutive series of dogs and cats managed for congenital portosystemic shunts. Forty-six dogs and 27 cats met the inclusion criteria of a congenital portosystemic shunt emanating from ...
Scott Daniel J - - 2013
Resuscitative endovascular balloon occlusion of the aorta (REBOA) is a potentially lifesaving maneuver in the setting of hemorrhagic shock. However, emergent use of REBOA is limited by existing technology, which requires large sheath arterial access and fluoroscopy-guided balloon positioning. The objectives of this study were to describe a new, fluoroscopy-free ...
Thomas Matthew P - - 2013
BACKGROUND: Post-cardiotomy cardiogenic shock is an infrequent devastating complication with few options for support. MATERIALS AND METHODS: We present a case highlighting use of the Impella 5.0 (ABIOMED; Danvers, MA) for postcardiotomy cardiogenic shock after coronary artery bypass and bioprosthetic aortic valve replacement. RESULTS: Support was maintained for 7 days ...
Iannucci Glen J - - 2013
A newborn with double outlet right ventricle, malposed great vessels, hypoplastic aortic arch, and coarctation of the aorta with no restriction to pulmonary blood flow underwent palliation with arch augmentation and placement of an intraluminal Dacron patch pulmonary artery band (PAB). She subsequently presented in shock because of profound hemolytic ...
Pawale Amit - - 2013
A 47-year-old woman with a mechanical mitral valve underwent a catheter-based atrial fibrillation ablation procedure, which was complicated by the dislodgment and immediate embolization of one of the valve leaflets. Acute severe mitral regurgitation and cardiogenic shock developed, necessitating emergency reoperative mitral valve re-replacement. She subsequently underwent a successful staged ...
Kaul Pankaj - - 2013
We present the case of a 68 year old Caucasian woman, in extremis, with left hemiparesis and right hemothorax, in hypovolemic shock, secondary to a blow-out of a large penetrating ulcer at the junction of innominate trunk and aortic arch. She underwent interposition graft replacement of innominate trunk and repair ...
Zhu Yu - - 2013
BACKGROUND: Previous studies have demonstrated differences among organs in terms of shock-induced vascular reactivity and a role for adenosine A2A receptors (A2ARs) in protection against ischemia/reperfusion injury. However, the contributions of A2ARs to organ-specific vascular reactivity and the protection of vascular responsiveness following shock are currently unknown. METHODS: We investigated ...
Currie S - - 2013
Rainbow trout (Oncorhynchus mykiss) exposed to an acute heat shock (1h at 25°C after raising water temperature from 13°C to 25°C over 4h) mount a significant catecholamine response. The present study investigated the proximate mechanisms underlying catecholamine mobilization. Trout exposed to heat shock in vivo exhibited a significant reduction in ...
Kumar Santosh - - 2013
Spontaneous rupture of adrenal pheochromocytoma is an extremely rare condition which presents as an abdominal catastrophe. Unrecognized, this transformation can rapidly lead to death. We report a case of a 63-year-old male who presented with hemorrhagic shock secondary to ruptured adrenal pheochromocytoma. The clinical course is notable for immediate transarterial ...
Soeda Takeshi - - 2013
An emergent operation was performed on a 73-year-old woman with massive hematuria and serious shock. A computed tomography (CT) revealed that the cause of the shock was hemorrhage from an aneurysm into the ureter, with resultant massive hematuria. During surgery, we observed that the ureter was encased into the wall ...
Aggarwal Nidhi - - 2013
Pulmonary artery (PA) catheterisation has been performed for over four decades. It is utilised in intensive care units and perioperatively to titrate fluid and pressor therapy. Major and minor complications have been reported. The catheter can infrequently loop and coil in the right atrium, right ventricle and superior vena cava ...
Lichtenstein D D Service de Réanimation Médicale, Hôpital Ambroise-Paré, Université Paris-Ouest, - - 2013
The assessment of acute circulatory failure is a challenge in absence of solid gold standard. It is suggested that artifacts generated by lung ultrasound can be of help. The FALLS-protocol (Fluid Administration Limited by Lung Sonography) follows Weil's classification of shocks. Firstly, it searches for pericardial fluid, then right heart ...
Pillarisetti Jayasree - - 2012
BACKGROUND: Massive pulmonary embolism (PE) complicated with shock has an extremely high mortality rate with medical treatment. Since access to emergency vascular surgery or endovascular specialists is not readily available in most centers, patients are frequently treated with thrombolytic agents delivered via a peripheral venous access. Patients with shock, however, ...
Yang Qiwei Q Department of Pediatrics, College of Medicine, University of Illinois at Chicago, Chicago, IL 60612, USA. - - 2012
High-altitude long-term hypoxia (LTH) is known to induce pulmonary arterial smooth muscle cell (PASMC) proliferation in the fetus, leading to pulmonary arterial remodeling and pulmonary hypertension of the newborn. The mechanisms underlying these conditions remain enigmatic however. We hypothesized that epigenetic alterations in fetal PASMC induced by high-altitude LTH may ...
Chao Alexander - - 2012
Temporary vascular shunts (TVSs) are relied on frequently in the current military theater. Details of their physiology and outcome are of increasing interest and needed to further define their place in the management of trauma. This study was conducted using a porcine hemorrhagic shock model and aimed to 1) establish ...
Li Tao T Laboratory of Anesthesiology and Translational Neuroscience Center, West China Hospital, Sichuan University, Chengdu, - - 2013
This study was designed to investigate whether polymerized human placenta hemoglobin (PolyPHb) attenuated hemorrhagic shock-induced lung injury. A mean arterial pressure (MAP) of 30mmHg was maintained for 60 min. Then, all the rats were randomly resuscitated with hetastarch, whole blood, or PolyPHb. The result indicated that PolyPHb greatly improved the ...
Lu Tzong-Shi TS Department of Medicine, Renal Division, Brigham and Women's Hospital, Harvard Medical School, Room 120, 41 Ave Louis Pasteurb, Boston, MA 02115, - - 2012
Vascular calcification (VC) is a significant contributor to cardiovascular mortality in patients with chronic kidney disease (CKD) and coronary artery disease (CAD). Osteo/chondrocytic transformation and simultaneous dedifferentiation of smooth muscle cells (SMCs) are important in the pathogenesis of VC. Heat-shock protein 72 (HSP72) is a cardioprotective inducible heat-shock protein that ...
Jaussaud N - - 2012
AIM: The goal of this study was to identify physical characteristics of primary intimal tears in patients arriving to the hospital alive with acute type A aortic dissection using 64-multislice computerized tomography (MSCT) in order to determine anatomic feasibility of endovascular stent-grafting (ESG) for future treatment. METHODS: Radiology database was ...
Hwang In Cheol - - 2012
Many studies have attempted to develop relatively simple and easy noninvasive measurements of atherosclerosis (NIMA), and each NIMA assesses different atherosclerotic properties. We, therefore, investigated the association between metabolic syndrome (MetS) components and different NIMAs. This study included 1,132 Korean subjects over 20 years of age who had visited a ...
Talati Megha M Department of Medicine, Vanderbilt University Medical Center, Nashville, Tennesse, - - 2012
The pathogenesis of idiopathic pulmonary hypertension is poorly understood. This paper utilized histology-based Matrix-Assisted Laser Desorption Ionization Mass Spectrometry (MALDI MS) to identify as-yet unknown proteins that may be associated with the structural changes in the pulmonary arterial walls of patients with IPAH. The technology identified significant increases in two ...
Bal Simerpreet S - - 2011
Metabolic syndrome (MetS) and its components are associated with increased risk of stroke and cardiovascular disease. Relationship of MetS to carotid atherosclerosis has not been documented well in North Indian population. (1) To determine the incidence of metabolic syndrome in asymptomatic healthy young North Indian population; (2) to evaluate individuals ...
Marone E M - - 2011
Optimal treatment for synchronous aortic aneurysms is still debated. Staged repair is advocated as the standard of care. Its disadvantage however is the consistent risk of rupture of the untreated aortic segment during recovery; moreover a considerable percentage of patients either refuse the second stage or is lost to follow-up. ...
Rapacciuolo Antonio - - 2011
Here we report a case of a 79-year-old woman with inferior myocardial infarction, transferred to our cath lab to perform a primary percutaneous coronary intervention (PPCI). During the procedure, a massive dissection complicated the thrombotic lesion of the right coronary artery (RCA). In this case, we decided to use the ...
Liu Ligang - - 2011
Objective: The aim of this study was to investigate the feasibility of transventricular-transseptal approach (TVSA) for extrapleural trans-catheter aortic valved stent implantation via a subxyphoidian access. Methods: In five porcine experiments (52.3±10.9kg) the right ventricle was exposed via subxyphoidian access. Under the guidance of intracardiac echocardiography (ICE) and fluoroscopy, the ...
Abdou Sayed M - - 2011
The optimal technique for bifurcation stenting of distal Left main (LM) lesions remains unestablished and controversial. Some techniques with superior stent apposition, such as culotte technique were supposed to be associated with lower rate of stent thrombosis. However, with culotte technique, the double-stent layer at the carina and in the ...
Prabhakaran Shyam - - 2011
Quantitative magnetic resonance angiography (QMRA) is a noninvasive imaging modality that provides anatomic and physiologic measurements of arteries. We used QMRA to assess hemodynamic changes following Wingspan stent placement for intracranial stenosis. We reviewed patients treated with Wingspan stents for intracranial stenosis who had baseline and follow-up QMRA data. We ...
Coogan Jessica Shih JS Department of Bioengineering, Stanford University, Stanford, California, - - 2011
In this work, we examine the effects of stent-induced aortic stiffness on cardiac workload and blood pressure using computational fluid dynamic simulations. Treatment of aortic coarctation (CoA) consists of either open, surgical repair or angioplasty with or without stenting. Although stenting is a minimally invasive alternative to surgery, aortic stiffness ...
Costa Ricardo A - - 2011
This repot reviews the angiographic and intravascular (IVUS) assessment of coronary bifurcation lesions. Overall, bifurcation lesion anatomy and morphology is critical for technical decision making, and a key factor for successful bifurcation PCI. Optimal viewing is essential for proper angiographic assessment, especially for evaluation of the degree of SB involvement. ...
Hecht Harvey S - - 2011
Objectives: To demonstrate the variety of stent abnormalities that may be evaluated by coronary computed tomographic angiography (CTA). Background: The application of CTA to the evaluation of coronary stents has focused almost entirely on the detection of in-stent restenosis. Methods: All CTA performed for stent evaluation at a single institution ...
You Qingjun - - 2011
Characterization of biodegradable stent vein graft thickening. Polydioxanone vascular sutures (PDSs) were used in a biodegradable arteriovenous bypass model. Twenty-four rabbits underwent carotid interposition bypass via ipsilateral jugular vein. One half received the stent (PDS group) and the remaining half a simple vein graft (controls). Group subsets received external stent ...
Demkow Marcin - - 2011
Objectives: To evaluate the effectiveness and safety of percutaneous pulmonary valve implantation (PPVI) with routine prestenting with a bare metal stent (BMS). Background: PPVI is a relatively new method of treating patients with repaired congenital heart disease (CHD). Results of PPVI performed with routine prestenting have never been reported. Methods: ...
Law Mark A - - 2011
Background: Pulmonary artery (PA) stents are utilized to treat branch pulmonary stenosis (BPS). Often patients with PA stents undergo subsequent cardiac surgery for other indications, and the stents can be manipulated during the procedure. Objective: The purpose of this study was to evaluate the outcome of branch PA stenoses following ...
Brilakis Emmanouil S - - 2011
We report a novel technique for retrieving lost stents or other equipment from the intravascular space. A hairpin is formed at the distal part of a 0.014 inch coronary guidewire, inserted through the Touhy valve, and used to "hook" the lost stent. The distal tip of the wire is then ...
Karabay Can Yucel - - 2011
Saddle pulmonary embolism (PE) is an embolus at the level of the bifurcation of the pulmonary trunk that extends into both main pulmonary arteries. Because of the unstable, large clot burden in the pulmonary artery and the risk of sudden haemodynamic collapse and sudden death, identifying a saddle embolus is ...
Carnelli Davide - - 2011
Mechanical properties of carotid stents are important for the selection of the implantable device. The efficacy of cell design is usually investigated on the basis of clinical follow-ups; however, for the specific carotid application the relative importance of the cell design on the stenting outcome is debated. Ideally, a carotid ...
Trani Carlo - - 2010
Percutaneous revascularization of superficial femoral artery (SFA) is increasingly carried out to treat patients with peripheral vascular disease and either intermittent claudication or critical limb ischemia. Transradial vascular access is increasingly adopted for invasive procedures due to reduced access-site complications and improved patient's comfort, compared with transfemoral. However, compared with ...
Schranz Dietmar - - 2010
Ductal stenting for pulmonary blood supply in newborns with cyanotic congenital heart disease (CHD) might be a low risk and safe alternative to the surgical aorto-to-pulmonary artery (AP) shunt in dual-source lung perfusion. Ductal stenting in truly duct-dependent pulmonary circulation has not been evaluated. Prospective interventional and clinical follow-up trial. ...
Costalat Vincent - - 2010
The limitations of the medical management of symptomatic intracranial arterial stenosis encourage the development of new therapeutic strategies such as intracranial stenting. To report and analyze the results of a series of 42 patients treated with 3 different endovascular techniques: isolated angioplasty, balloon-expandable coronary stents, and the Wingspan self-expandable intracranial ...
Nietlispach Fabian - - 2010
Endovascular stenting of aneurysms late after surgical repair of coarctation may have to deal with marked changes in aortic diameter proximal and distal to the aneurysm. We report our first-in-man successful use of a custom-made tapered (variable diameter) covered stent. The aneurysm was 42 mm in diameter with a length ...
Zhu Yue-Qi - - 2010
We report the technical success rate and mid-term follow-up results after deploying stent-grafts to treat a cohort of patients with symptomatic complicated intra- or extracranial aneurysms (SCIEAs). This study was a retrospective review of 58 patients (39 male; mean age 40.4 ± 12.3 years) with 60 SCIEAs treated by 67 ...
Saari Petri - - 2011
To evaluate the response of various stent grafts after needle fenestration and sequential dilation with standard percutaneous transluminal angioplasty (PTA) and cutting balloons and sealing of the fenestration with a side branch stent graft. Five commercially available aortic stent grafts (Endurant, Gore TAG, Talent, Valiant, and Zenith) were fenestrated with ...
Moore James E JE - - 2010
The treatment of atherosclerotic plaques near and involving coronary bifurcations is especially challenging for interventional procedures. Optimization of these treatment strategies should begin with an understanding of how disease came to be localized to these regions, followed by careful design of the interventional tools and implanted devices. This manuscript reviews ...
Auricchio F - - 2011
The outcome of carotid artery stenting (CAS) depends on a proper selection of patients and devices, requiring dedicated tools able to relate the device features with the target vessel. In the present study, we use finite element analysis to evaluate the performance of three self-expanding stent designs (laser-cut open-cell, laser-cut ...
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