Search Results
Results 301 - 350 of 1006
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Ruigrok Ynte M - - 2008
BACKGROUND: Genetic factors are likely to be involved in the pathogenesis of intracranial, ascending thoracic aorta, and infrarenal aortic abdominal aneurysms. Common genetic risk factors for these three types of aneurysms have been suggested. This review describes the results of whole-genome linkage studies on intracranial, thoracic aorta, and aortic abdominal ...
Hoshi Taku - - 2008
BACKGROUND: The levels of systemic inflammatory markers have been shown to predict future cardiovascular events, but whether they are associated with intracranial large-artery atherosclerosis is uncertain. We investigated the relation between the level of inflammatory markers interleukin-6 (IL-6) and high-sensitivity C-reactive protein (hsCRP) and subclinical intracranial large-artery atherosclerosis in patients ...
Guo Fuyou - - 2007
OBJECTIVE: To investigate apoptosis in vascular smooth muscle cells (VSMCs) and caspase-3 expression in ruptured intracranial aneurysm. METHODS: Tissue samples of 15 ruptured intracranial aneurysms, 6 abdominal aortic aneurysms (AAA) and 6 normal vessels were evaluated. Apoptosis in VSMCs was determined on transmission electron microscopy. Immunohistochemistry for alpha-SMC actin and ...
Kan Peter - - 2007
The acronym PHACES describes a rare neurocutaneous syndrome that comprises posterior fossa malformations, facial hemangiomas, arterial anomalies, coarctation of the aorta and cardiac defects, eye abnormalities, and sternal defects. Facial hemangiomas constitute the hallmark of this disorder. Giant intracranial aneurysms have not been previously reported in the literature as manifestations ...
Cleveland Trevor - - 2007
Stroke is a major cause of morbidity and mortality in the modern world. Carotid artery atheromatous disease is responsible for a significant number of these events. The effects of carotid artery disease may be prevented by appropriate treatment. All patients with known atheromatous disease should be treated with medical therapy. ...
Fattori Rossella - - 2007
The incidence of thoracic aortic aneurysms (TAAs) is increasing with the present rate of occurrence at 10.9 cases per 100,000 people per year. The estimated 5-year risk of rupture of a TAA with a diameter between 4 and 5.9 cm is 16%, but it rises to 31% for aneurysms ≥ 6 ...
Bang O Y - - 2007
BACKGROUND: Adiponectin is a protein secreted by adipose cells that improves insulin sensitivity and possesses antiatherogenic properties. In this study, we investigated the relationship between adiponectin levels and ischemic stroke subtype. METHODS: Using clinical, imaging, and laboratory data, 231 consecutive patients admitted to a university medical center over a 2-year ...
De Silva Deidre Anne - - 2007
The site of vascular stenosis correlates well with the Oxfordshire Community Stroke Project (OCSP) classification among Caucasians, but not among ethnic Chinese patients. We prospectively studied 205 consecutive ethnic South Asian ischemic stroke patients to investigate the prevalence of intracranial large artery disease determined by transcranial color-coded doppler and magnetic ...
Marazzi M G - - 2008
Chronic mucocutaneous candidiasis (CMC) is a syndrome characterised by immune deficiency, often presenting familial dominant inheritance and association with autoimmune endocrinopathies. We report on a patient with CMC who died at 5 years of age of a brain haemorrhage following the rupture of a basilar-artery aneurysm. Candida hyphae in the ...
Zink Walter E - - 2007
BACKGROUND AND PURPOSE: Abnormal arterial flow dynamics and intracranial collateral pathways can be seen in patients with congenital internal carotid artery (ICA) aplasia or hypoplasia. Here we seek to evaluate whether ICA aplasia/hypoplasia is associated with an increased prevalence of intracranial saccular aneurysm relative to carotid rete mirabile. METHODS: We ...
Raymond J - - 2007
Preventive treatment of unruptured intracranial aneurysms is often performed but has never been proved beneficial as compared to conservative management. In a context of uncertainty, the 'best treatment' that can be offered to each individual is a chance to be treated and thus to be protected from rupture of the ...
Matharu Manjit S - - 2007
Thunderclap headache (TCH) refers to an excruciating headache of instantaneous onset. Recognition and accurate diagnosis of this headache are important because it can be caused by various serious underlying brain disorders such as subarachnoid hemorrhage, intracranial hematoma, cerebral venous sinus thrombosis, cervical artery dissection, ischemic stroke, pituitary apoplexy, acute arterial ...
Cerrato P - - 2007
Moya-Moya is a rare cerebrovascular occlusive disease characterized by bilateral stenosis or occlusion at the terminal portion of the internal carotid artery and abnormal vascular network at the base of the brain, named "moya-moya". In children, Moya-Moya disease usually presents with ischemic cerebrovascular events, mainly TIA or lacunar stroke, leading ...
Johnson Stephen P - - 2007
Treatment of hepatic artery to portal vein fistulas (HAPFs) has shifted in the past two decades from surgical resection of the involved liver to embolization. A uniform technique for percutaneous intervention has not been established because the approach is influenced by the size, location, and number of feeding arteries. We ...
D'Angelo Michael W - - 2007
Successful transcatheter arterial embolization of symptomatic adrenal aldosteronoma in a 56-year-old woman with hypertension and hypokalemia is described. The presentation, diagnosis, and treatment of aldosterone-producing tumors are subsequently discussed.
Gaba Ron C - - 2007
Carotid artery blowout is a devastating complication of head and neck malignancy, irradiation, and trauma. New endovascular therapies of acute carotid artery rupture involve stent-directed, carotid-sparing treatment strategies. We report a case of successful covered stent treatment of carotid artery hemorrhage in the setting of head and neck cancer and ...
Miyazawa N - - 2007
This study investigated the association of intracranial aneurysms and abdominal aortic aneurysms to elucidate the incidence and independent risk factors for this association. Ultrasonography of the abdominal aorta was performed in 181 patients with 224 intracranial aneurysms. Six patients had suffered subarachnoid haemorrhage and the others had chronic disease or ...
Schievink Wouter I - - 2007
Myelography showed an opening pressure of 0 cm H2O and multiple thoracic meningeal diverticula in a 52-year-old woman suffering from orthostatic headaches of instantaneous onset. MR-angiography showed severe segmental arterial stenosis of the anterior and posterior circulation, which resolved over a 4-day period following an epidural blood patch. Spontaneous intracranial ...
Ferroli Paolo - - 2007
OBJECTIVE: Self-closing nitinol U-clips (Medtronic, Inc., Minneapolis, MN) have been used to create vascular microanastomoses by vascular surgeons. This device eliminates the need for suture management and knot tying. Therefore, a high-quality interrupted microvascular anastomosis can be obtained in a shorter period of time. This is the first report of ...
Matsushige Toshinori - - 2007
Meningeal haemangiopericytomas (HPC) are malignant intracranial neoplasms that commonly recur and metastasize. Large size at diagnosis, abundant intracranial feeders and the risk of intraoperative bleeding can make them difficult to completely remove in one operation. We report here a rare case of a giant HPC which was treated successfully using ...
Nair S
The management of of unruptured intracranial aneurysms is one of the most important issues confronting neurosurgeons today. The high mortality and morbidity associated with subarachnoid hemorrhage (SAH) has prompted interest in repair of aneurysms that are discovered before they have ruptured. A strong risk factor for intracranial aneurysm which causes ...
Curto Lorenzo - - 2007
Coexistence of pituitary adenoma, intracranial meningioma and cerebral aneurysm has never been described. We report on a patient with GH-secreting pituitary macroadenoma associated with a right frontal meningioma and with two intracavernous asymptomatic aneurisms. A 61-year-old woman was referred to our Endocrine Unit 13 years after a right frontal craniotomy ...
Scozzafava James - - 2007
There are a number of causes of raised intracranial pressure (ICP) following aneurysm rupture. These include primary and diffuse hypoxic brain injury, intracranial hematomas, cerebral ischemia or infarction, and obstructive hydrocephalus. More localized brain swelling can also occur: the result of vasogenic and cytotoxic edema resulting from overlying bleeding in ...
SanuĊŸ Galip Zihni - - 2007
OBJECTIVE: Hunterian ligation of the internal carotid artery is an acceptable treatment modality for inoperable intracranial carotid aneurysms. Despite the risk of thrombo-embolic complications, ligation together with superficial temporal artery-middle cerebral artery (STA-MCA) bypass surgery is vital in some patients. Our aim is to present our experience in five patients ...
Meyers Philip M - - 2007
Intracranial atherosclerosis is a common cause of stroke. Although it has been recognized for decades, the lack of successful treatment strategies has limited clinical interest until recently. We review the natural history and pathophysiology of intracranial atherosclerosis. Vascular biomechanics are important to define differences between cerebral arteries and extracranial vessels ...
Blanc R - - 2006
INTRODUCTION: Tortuous vasculature is a cause of failure of endovascular treatment of intracranial vascular lesions. We report our experience of direct cervical accesses in patients in whom the arterial femoral route was not attainable. METHODS: In this retrospective study, 42 direct punctures of the carotid or the vertebral arteries at ...
Kim E Y - - 2006
Thin-section noncontrast CT (NCT) can detect thrombi in large arteries and can provide a measure of thrombus composition based on Hounsfield Units (HU). A study using polyethylene tubes as a model of intracranial arteries concluded that the HUs of platelet-rich thrombi are lower than those of erythrocyte-rich thrombi. Thrombus HUs ...
Peters Philip J - - 2006
A 41-year-old right-handed man with bicuspid aortic valve and a 3-month history of chronic fever and weight loss presented with sudden onset of severe headache. Computerised tomography of the head revealed a right basal ganglia haemorrhage. Further investigation documented Streptococcus mitis bacteraemia, a fusiform right middle cerebral artery aneurysm, and ...
Baccin Carlos E - - 2007
We describe two previously unreported cases with complete or incomplete expression of PHACES syndrome, a rare congenital syndromal pediatric disorder, which is characterized by posterior cranial fossa malformations, large facial hemangiomas, arterial anomalies, coarctation of the aorta and cardiac defects, abnormalities of the eye, sternal and supraabdominal raphe defects. These ...
Ruigrok Ynte M - - 2006
Intracranial aneurysm is probably a complex disease with both genetic and non-genetic or environmental risk factors contributing to the etiology of the disease. A disruption of the extracellular matrix (ECM) of the arterial wall is a likely factor in the pathogenesis of intracranial aneurysms. We analyzed 44 potential candidate genes ...
Steiger H-J - - 2006
Prevention in healthcare is attracting more and more attention. Early identification and correction of anomalies harbouring the risk of a catastrophic event such as aneurysms is the principal rationale for brain check-up programmes. The other aim of preventive screening is to identify progressive lesions with little reversibility such as gliomas. ...
Pannu Hariyadarshi - - 2006
OBJECT: Matrix metalloproteinases (MMPs) are a family of endopeptidases that mediate vascular remodeling by degrading extracellular matrix components, such as collagen and elastin. On the basis of accumulating evidence that implicates increased MMP-2 (gelatinase A) and MMP-9 (gelatinase B) amounts and activity in the pathogenesis of aneurysms, the authors investigated ...
Marques Robinson M - - 2006
Vein of Galen aneurysm is a rare pathology, representing less than 1% of intracranial vascular malformations. We report on a 65-year-old man who experienced a generalized tonic-clonic seizure. Brain imaging showed a large calcified expanding mass in the pineal region, confirming the diagnosis of a vein of Galen aneurysm. Because ...
Pinto Fernando Campos Gomes - - 2006
A case of an intracranial arterial aneurysm at internal carotid bifurcation in a 10-year-old girl is described with the special features of cerebral aneurysm which occur in children, comparing with the adults. We alert for the necessity of carefully operative technique in order to avoid damage and intraoperative rupture of ...
da Costa L B - - 2006
The association between the formation of intracranial aneurysms and situations of increased blood flow in certain areas of the brain is well accepted today. It has been seen in association with arteriovenous malformations of the brain, carotid occlusion, and Moyamoya disease. The occurrence of aneurysms in small arteries of the ...
Li Ming-Hua - - 2006
Vascular diseases like aneurysms, pseudoaneurysms and direct high-flow carotid-cavernous fistulas on the intracranial segment of the internal carotid artery are usually managed through transarterial embolization with detachable coils or balloons. Utility of covered stents has been reported with good results in the treatment of selective cases. But the current generation ...
Spelle Laurent - - 2006
Endovascular therapy has become the key therapeutic option in intracranial aneurysm management. Safe and successful embolization requires familiarity with the devices and techniques used and keen awareness of the potential pitfalls and complications. This article is an up-to-date review of the technical aspects of endovascular therapy in intracranial saccular aneurysms, ...
Sciubba Daniel M - - 2006
Ionizing radiation therapy is associated with pathological vascular changes in intracranial vessels, most commonly in the form of vessel thrombosis and occlusion. The development of an intracranial aneurysm following such therapy, however, is far less common. In this report the authors describe a 24-year-old man in whom a distal middle ...
Molyneux Andrew J AJ Department of Neuroradiology, University of Oxford, Woodstock Road, Oxford 0X2 6HE, United Kingdom. - - 2006
The last 14 years has seen a revolution in the management of intracranial aneurysms; endovascular coil treatment has moved from a minority marginal treatment applicable to a few patients in a few centers to become the mainstay of treatment of ruptured intracranial aneurysms. This article highlights new information learned from ...
Schwedt Todd J - - 2006
Thunderclap headache (TCH) is head pain that begins suddenly and is severe at onset. TCH might be the first sign of subarachnoid haemorrhage, unruptured intracranial aneurysm, cerebral venous sinus thrombosis, cervical artery dissection, acute hypertensive crisis, spontaneous intracranial hypotension, ischaemic stroke, retroclival haematoma, pituitary apoplexy, third ventricle colloid cyst, and ...
Hashimoto Tomoki - - 2006
Abnormal vascular remodeling mediated by inflammatory cells has been identified as a key pathologic component of various vascular diseases, including abdominal aortic aneurysms, brain arteriovenous malformations and atherosclerosis. Based on findings from observational studies that analysed human intracranial aneurysms and experimental studies that utilized animal models, an emerging concept suggests ...
Tsai Meng-Han - - 2006
A 26-year-old young man, had Graves' disease in hyperthyroid state, presented with frequent episodic transient left hemiparesis and mild slurred speech lasting for few minutes to 2 hours for one month. Infarction at posterior limb of right internal capsule was found on brain MRI. Angiography revealed multiple intracranial arteries stenoses ...
Erdogmus Senem - - 2006
The intracranial and intracanalicular portions of the ophthalmic artery is suspectible to various diseases and injuries; therefore, knowledge of the microanatomy of the complex bony, dural, vascular, and neural relationships of this segment is necessary for proper diagnosis and preservation of the neurovascular structures during subfrontal, pterional and intracanalicular procedures. ...
Reinert Michael - - 2006
The treatment of intracranial aneurysms is changing as endovascular obliteration possibilities and long-term results are being published in regard to outcome. However, not all aneurysms are amenable to direct endovascular or surgical treatment. In such situations, a high flow bypass for flow preservation can be considered as indirect treatment alternative, ...
Hsu S-W - - 2006
For better understanding of relevant morphology and mechanics, direct visualization of a Neuroform microstent (NFM) within an actual human intracranial artery is essential. Twelve NFM were deployed into 8 various segments of formaldehyde-fixed cadaver intracranial arteries. The arteries were then dehydrated and cleared in methyl salicylate to create transparency. The ...
Radhakrishnan M - - 2006
Prolonged QT interval and increased QT(C) dispersion have been described immediately following rupture of intracranial aneurysm, due to increased sympathetic activity. Here, we report a patient with transient prolongation of the QT interval, probably due to heparin-induced hypocalcaemia, which occurred during coiling of a right internal carotid aneurysm, 54 days ...
Morgan L - - 2006
BACKGROUND AND AIMS: An important part is played by inflammation in intracranial aneurysm formation. The hypothesis that there is an association of the proinflammatory cytokine interleukin-6 (IL-6) genotypes (-572G>C and -174G>C) with intracranial aneurysms was tested. METHODS: IL-6 genotypes were determined in 91 Caucasian patients with aneurysms and compared with ...
Maira Giulio - - 2006
The management of intracranial aneurysms (IAs) remarkably improved due to the development of diagnostic and surgical procedures. Subarachnoid hemorrhage (SAH) from IA rupture constitutes a devastating event, whose prognosis remains unsatisfactory. At present, several researchs are targeted to individuate subjects harboring unruptured IAs and those presenting a higher risk for ...
Barriales-Villa Roberto R Servicio de Cardiología, Complexo Hospitalario de Pontevedra, Pontevedra, - - 2006
Recent years have witnessed a change in our perception of congenital coronary artery anomalies. From being regarded as simple coronary angiographic observations of little clinical significance, they have come to be seen as potential causes of sudden death in young people and of myocardial ischemia in adults. Diagnostic difficulties, a ...
Agrawal Sumeet - - 2007
Behcet's disease is a systemic inflammatory disease characterized commonly by oral and genital ulcerations, with skin and eye involvement. Unlike other manifestations, involvement of the central nervous system and vascular manifestations can be late in the course and are the leading causes of death. Aneurysms are relatively common in visceral ...
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