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Pachon Ronald R Cardiovascular Research Institute, Department of Cell Biology and Molecular Medicine, Rutgers-New Jersey Medical School, Newark, USA - - 2014
Sudden cardiac death in 5-10% of cases is explained by patients with congenital abnormalities that include coronary artery malformations such as anomalous origin of the left coronary artery from the pulmonary artery (ALCAPA). We report a case of sudden cardiac death as the first presentation of ALCAPA in a young ...
Wolfson Aaron M AM Section of Cardiology, Department of Medicine, University of Chicago, 5841S Maryland Ave, MC5403, L08, Chicago, IL, 60611, - - 2014
Pulmonary arterial hypertension (PAH) is a rare, progressively worsening disease characterized by dysfunction among endothelial and smooth muscle cells within the pulmonary vasculature with a resultant increase in pulmonary vascular resistance, right ventricular maladaptation and failure, and ultimately early death. The three major therapeutic classes of medications available to treat ...
Izgi Cemil C Department of Cardiology, International Hospital, Istanbul, - - 2014
Clinical significance of coronary arteries with anomalous origin and/or course is highly heterogeneous. Anomalies with the origin from the opposite sinus and interarterial course can be associated with angina, syncope, and sudden cardiac death. However, there are no clear guidelines for diagnosis and treatment of such cases. We present the ...
Hamilton Heidi H HH Medical and Forensic Autopsy Section, Department of Pathology and Laboratory Medicine, Medical University of South Carolina, 171 Ashley Avenue, MSC 908, Charleston, SC, - - 2014
Indwelling intravascular catheters provide convenient access to healthcare personnel and also recreational intravenous drug users who inject suspensions of oral medications. A nine-case series of autopsies of clinically stable decedents with indwelling catheters and sudden death is herein presented. Pulmonary histologic findings were consistent with intravenous administration of oral medications ...
Jeon Y J - - 2014
We found 3 right and 2 left renal arteries with asymmetrical origins in a 61-year-old Korean male cadaver, whose cause of death was 'laryngeal carcinoma'. According to a previous classification, the first and second right renal arteries correspond to the early division and other renal arteries - to the extra ...
Idrees Jahanzaib J Department of Thoracic and Cardiovascular Surgery, Heart and Vascular Institute, Cleveland Clinic, Cleveland, - - 2014
Persistent retrograde false lumen perfusion is a common mode of failure after thoracic endovascular aortic repair (TEVAR) for chronic dissection. Objectives were to describe a novel endovascular approach for false lumen occlusion and assess outcomes. From 2009 to 2013, 21 patients (mean age, 64 ± 11 years) with chronic thoracoabdominal dissection underwent ...
Vlajković Slobodan S Department of Anatomy, University of Niš, Faculty of Medicine, 81 Dr Zoran Đinđić Blvd., 18000 Niš, Serbia. Electronic address: - - 2014
Unusual widening of the posterior communicating artery (PCoA) at its beginning from the cerebral portion of the internal carotid artery (ICA) was described as its infundibular dilatation (ID). A possibility of ID rupture or progression to aneurysm was the reason for an investigation of its frequency and morphologic features in ...
Massoni Francesco F From the Departments of Anatomical Sciences, Histological, Legal Medicine, and Locomotor Apparatus, Sapienza University of Rome, Rome, - - 2014
Quadricuspid aortic valve is a very rare cardiac malformation (<1.46%) that is very rarely associated with other diseases, such as ascending aortic aneurysm.The authors present a case of cardiac tamponade from a rupture of the ascending aortic aneurysm that may have been caused, as shown by a review of the ...
Acker Shannon N SN Division of Pediatric Surgery, Department of Surgery, Children's Hospital Colorado, University of Colorado School of Medicine, Aurora, CO; Pediatric Heart-Lung Center, Children's Hospital Colorado, University of Colorado School of Medicine, Aurora, CO. Electronic address: - - 2014
To determine whether prominent intrapulmonary anastomotic vessels (IPAVs) or bronchopulmonary "shunt" vessels can be identified in lungs from infants with fatal congenital diaphragmatic hernia (CDH). We performed histology with immunostaining for CD31 (endothelium) and D2-40 (lymphatics), along with high-precision 3-dimensional (3D) reconstruction on lung tissue from 9 patients who died ...
Pak Misun M Division of Cardiology, Shimane University Faculty of - - 2014
Giant cell arteritis (GCA) is an autoimmune disease characterized by granulomatous inflammation in the wall of medium-sized and large-sized arteries, and it usually occurs in patients over 50 years of age.(1)) Symptoms are nonspecific, and include fatigue, fever, and headache.(2)) It is occasionally combined with aortic complications, and ruptures resulting ...
Hardy Curtis Lamar CL Department of Graduate Medical Education, Naval Medical Center Portsmouth, Portsmouth, - - 2014
The breakdown of previously inserted intravascular devices can lead to microemboli that can clinically mimic the symptoms of common disorders, such as senile purpura, and have subtle histologic findings. However, device failure can occur gradually and start months after placement. If not identified early, microemboli to noncutaneous sites can cause ...
Neukamm Christian C Section for Paediatric Heart Diseases, Rikshospitalet, Oslo University Hospital, Norway - - 2014
From a population of 90 patients after pulmonary valve replacement with a biological valve (Carpentier-Edwards Perimount valve), 56 of 80 available patients were examined five years after surgery. Pulmonary valve replacement is needed in many patients with congenital heart disease. Homografts have limited availability and predictable degeneration, and mechanical valves ...
Formica Francesco F Department of Surgery and Translational Medicine, Cardiac Surgery Clinic, San Gerardo Hospital, University of - - 2014
Anomalous origin of the left coronary artery from the pulmonary artery (ALCAPA) is a rare congenital coronary artery defect leading to sudden cardiac death. Diagnosis is made after the onset of symptoms, mainly in the pediatric population. We describe an uncommon presentation of ALCAPA and rheumatic mitral valve regurgitation, diagnosed ...
Roberts Carey Camille CC Baylor Heart and Vascular Institute (C. C. Roberts, Ko, W. C. Roberts), the Department of Pathology (Snipes, W. C. Roberts, Guileyardo), and the Division of Cardiology, Department of Internal Medicine (W. C. Roberts), Baylor University Medical Center at Dallas. C. C. Roberts is a second-year medical student at Georgetown University School of Medicine, Washington, - - 2014
Sudden death from intracerebral hemorrhage was observed in two patients admitted to Baylor University Medical Center at Dallas in a single month. Each had been drinking alcohol at the time of onset of first symptoms. Intracerebral hemorrhage was diagnosed in one patient by computed tomography, but not in the second ...
Michelis Katherine C KC Zena and Michael A. Wiener Cardiovascular Institute, and Cardiovascular Research Center, Icahn School of Medicine at Mount Sinai, New York, New - - 2014
Fibromuscular dysplasia (FMD) involving the coronary arteries is an uncommon but important condition that can present as acute coronary syndrome, left ventricular dysfunction, or potentially sudden cardiac death. Although the classic angiographic "string of beads" that may be observed in renal artery FMD does not occur in coronary arteries, potential ...
Brothers Julie A JA Division of Cardiology, Department of Pediatrics, The Children's Hospital of Philadelphia and Perelman School of Medicine at the University of Pennsylvania, Philadelphia, Pennsylvania. Electronic address: - - 2014
Congenital coronary anomalies in which the coronary artery arises from the contralateral aortic sinus of Valsalva are associated with fatal arrhythmias and sudden death. The mechanism causing sudden death has been debated. We describe a case of an adolescent patient with right coronary artery arising leftward, but from the right ...
Cui Bin B Department of Cardiovascular Surgery, Fu Wai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Science and Peking Union Medical College, Beijing, China - - 2014
The purpose of this retrospective study was to evaluate a two-stage double switch operation, morphological left ventricular (mLV) retraining followed by an atrial-arterial switch operation, in the management of patients with congenitally corrected transposition of the great arteries (CCTGA) and a deconditioned mLV. Between May 2005 and May 2011, 14 ...
Gashouta Mohamed A MA Department of medicine, division of pulmonary and critical care medicine, Johns Hopkins University school of medicine, Saint Luke's hospital, 232 S Woods Mill Road, Baltimore, MD, 21224, United States; Saint Luke's Hospital, 232 S Woods Mill Road, Chesterfield, MO 63017, United States. Electronic address: - - 2014
Pulmonary arterial hypertension (PAH) is one of the leading causes of death in systemic sclerosis (SSc). Despite advances in treatment options for PAH, long-term prognosis remains poor for scleroderma-associated PAH (SSc-PAH). Although prompt diagnosis and treatment of PAH may have significant impact on survival rates, early detection of the syndrome ...
Ergun Onur O Department of Radiology, Diskapi Yildirim Beyazit Training and Research Hospital, Ankara, - - 2014
We present a case of a 14-year-old boy with spontaneous intracranial hemorrhage that was referred to us to confirm the diagnosis of brain death with cerebral angiography. In the left carotid angiogram, there was no arterial flow above the craniovertebral junction. But in the right carotid angiogram, there was arterial ...
Kanter Kirk R KR Division of Cardiothoracic Surgery, Department of Surgery, Emory University School of Medicine, Atlanta, Georgia; Pediatric Cardiac Surgery, Children's Healthcare of Atlanta at Egleston, Atlanta, Georgia. Electronic address: - - 2014
Pulmonary vein stenosis (PVS), both congenital and acquired, is challenging to treat surgically with uncertain long-term results. We reviewed an 11-year surgical experience in 52 children. From 2002 to 2012, 52 children age 0 days to 13 years (mean 1.9 years, median 11.7 months) weighing 2.2 to 32.5 kg (mean ...
Coselli Joseph S JS Division of Cardiothoracic Surgery, Michael E. DeBakey Department of Surgery, Baylor College of Medicine, Houston, Tex; Department of Cardiovascular Surgery, Texas Heart Institute, Houston, Tex; Baylor St Luke's Medical Center, Houston, Tex. Electronic address: - - 2014
In patients with acute DeBakey type I dissection, endovascular repair of the descending thoracic aorta during proximal aortic repair is an increasingly popular approach to preventing distal aortic sequelae and subsequent repair. To better define the risks and outcomes associated with these secondary operations, we examined our contemporary experience with ...
Dubey Laxman L Department of Cardiology, College of Medical Sciences and Teaching Hospital, Bharatpur, Chitwan, - - 2014
Spontaneous coronary artery dissection (SCAD) is a rare cause of acute coronary syndrome (ACS) and sudden death. It usually occurs in young women during the peripartum period; however, it had also been reported in older aged males having risk factors for atherosclerotic coronary artery disease. This case describes a 69-year-old ...
Imori Yoichi Y Department of Cardiovascular Medicine, Shonan Kamakura General Hospital, Kanagawa, - - 2014
A 45-year-old man previously diagnosed with myxomatous mitral valve disease was admitted to our hospital with chest pain at rest and on effort. Contrast-enhanced CT revealed that the patient's right coronary artery originated from the left sinus Valsalva, which was compressed between the aortic and pulmonary roots. This anatomical abnormality ...
Mery Carlos M CM Coronary Anomalies Program, Texas Children's Hospital, Houston, Texas; Michael E. DeBakey Department of Surgery, Texas Children's Hospital/Baylor College of Medicine, Houston, Texas. Electronic address: - - 2014
Anomalous aortic origin of a coronary artery (AAOCA) is a congenital abnormality of the origin or course of a coronary artery that arises from the aorta. It is the second most common cause of sudden cardiac death in young athletes. Its exact prevalence, the pathophysiological mechanisms that cause sudden cardiac ...
Rot Uroš U Department of Neurology, University Medical Centre, Zaloška cesta 2, 1525 Ljubljana, Slovenia. Electronic address: - - 2013
A 31-year-old woman with MS developed livedo reticularis and secondary Raynaud phenomenon 2.5 years after introduction of interferon beta-1b. The symptoms disappeared after withdrawal of the drug. Livedo reticularis and Raynaud phenomenon as well as pulmonary arterial hypertension, venous sinus thrombosis, pulmonary embolism and renal thrombotic microangiopathy have all been ...
Caixeta Adriano - - 2013
A 60-year-old man with a history of implantation of two bare-metal stents 2 years prior presented to the emergency department with new-onset chest pain. He has been regularly taking angiotensinconverting enzyme inhibitors, beta blockers and aspirin. Aspirin was suspended for 10 days prior to the current hospitalization in order to ...
Tamenishi Akinori - - 2013
A 63-year old man was admitted to hospital for the treatment of coincidental infected distal arch and abdominal aortic aneurysms. His haemodynamic state was unstable and uncontrollable because of septic shock. Group A beta-haemolytic Streptococcus pyogenes was the responsible microorganism. An emergent extra-anatomical bypass and complete aneurysm excisions were performed ...
Maisawa Kazuma K Department of Cardiovascular Surgery, Saitama City Hospital, Saitama City, Saitama, - - 2013
Objectives: many studies have shown that oral beta blockers reduce the incidence of atrial fibrillation after coronary artery bypass. The goal of this study was to determine whether landiolol, an intravenous beta blocker, reduces the incidence of atrial fibrillation after off-pump coronary artery bypass. Methods: 39 consecutive patients were given ...
Agrawal Sandeep K - - 2013
Cellular adhesion on the surface of Guglielmi detachable coils (GDC) promotes accelerated occlusion of aneurysms. We hypothesized that coils coated with transforming growth factor beta (TGF-beta) and vascular endothelial growth factor (VEGF) will promote clot organization and endothelial or cellular proliferation to facilitate closure of large experimental aneurysms relative to ...
Thomas Jimmy A - - 2011
Anomalous coronary arteries pose a great challenge during percutaneous intervention due to various technical factors. Inadequate guide support leads to significant obstacles for delivery of interventional devices to stenotic areas. Several methods have been proposed to overcome these obstacles. We present a novel technique where we used the Guideliner support ...
Carniato S - - 2011
SUMMARY:We report a novel model of arterial tortuosity in the porcine brachial artery for testing of endovascular devices in the flexed forelimb position. This provides an ideal vascular territory for an in vivo assessment of guidewires, microcatheters, and endovascular implants because it closely mimics the challenging curvature at the carotid ...
Bernal Lucas Ribé - - 2011
This is one of the first reports of a left subclavian pseudoaneurysm in a patient presenting with massive hemoptysis. We present a challenging case of a patient who consulted for hemoptysis. Imaging revealed a left subclavian artery pseudoaneurysm that caused a pulmonary parenchymal lesion. Treatment with a self-expanding thoracic stent-graft ...
Brieda Marco - - 2011
Upgrading of a pacing system in the presence of a subclavian occlusion is technically challenging. We describe the case of a patient who underwent a successful upgrading procedure of an implantable cardioverter-defibrillator (ICD) to a biventricular defibrillator (ICD-CRT) in the presence of a suboccluded left subclavian vein, using a collateral ...
Fediuk Jena - - 2012
Actin polymerization (APM), regulated by Rho GTPases, promotes myocyte force generation. Hypoxia is known to impede postnatal disassembly of the actin cytoskeleton in pulmonary arterial (PA) myocytes. We compared basal and agonist-induced APM in myocytes from PA and descending aorta (Ao), under hypoxic and normoxic conditions. We also examined effects ...
Rubinstein Chen - - 2011
Gluteal aneurysms are rare entity, whose surgical or endovascular management is traditionally challenging. Infectious source being increasingly more common as the underlying etiology. We herein describe successful implementation of direct thrombin injection as another therapeutic option for these patients.
Barboza Joaquim - - 2011
Aortic stenosis (AS) is one of the most common valvular disorders affecting the aging US population. Although guidelines published by leading cardiac societies outline diagnostic and management strategies for this condition, in daily practice clinicians face dilemmas when trying to confirm the diagnosis of severe AS because of discrepancies in ...
Lingadevaru Hemanth - - 2011
Extracorporeal life support (ECLS) is used to support patients with pulmonary alveolar proteinosis (PAP) both during acute illness and during lung lavage therapies. We report the challenges encountered while providing ECLS for respiratory failure to a 12-year-old girl with PAP who had previously received ECLS as a toddler for a ...
Planer David - - 2011
Reintervention due to endoleak of aortic endograft repair is often challenging. Herein, we report endovascular endoleak repair in a patient with previous thoracic and abdominal endovascular grafts with extensive coverage of the aorta. The present technique included snorkeling of the celiac trunk to preserve antegrade flow in the celiac artery ...
Kasiri Saeid - - 2011
Stenting of curved arteries is generally perceived to be more challenging than straight vessels. Conceptually implanting multiple shorter stents rather than a single longer stent into such a curved artery represents a promising concept, but little is known about the impact of such an approach. The objective of this study ...
Indermuhle Andreas - - 2011
Recanalization of chronic total occlusions via grafts has been described previously. However, the insertion of the graft into the distal vessel is often characterized by an unfavorable entry angle which renders an antegrade approach challenging. In the present case, we describe how retrograde recanalization of the proximal right coronary artery ...
García Franco C - - 2011
Arterial prosthetic graft infection is one of the most challenging issues in vascular surgery. We report a case of an infected descending thoracic aorta endograft, presenting itself several years after placement, with hemoptysis and back pain as referred symptoms. The patient was successfully treated by removing the thoracic aorta and ...
Stein Jeffrey - - 2011
The median arcuate ligament can compress the proximal portion of the celiac artery causing symptoms of chronic mesenteric ischemia. This rare condition typically affects young women and often poses a diagnostic challenge. Compression of the superior mesenteric artery (SMA) in addition to the celiac artery represents an unusual variant of ...
Kogon Brian E - - 2011
Many congenital heart defects require reconstruction of the right ventricular outflow tract utilizing a right ventricle to pulmonary artery conduit. One of the challenges with these conduits is the development of conduit stenosis. This phenomenon is quite common and typically results from a combination of progressive calcification, fibrosis, and/or the ...
Kirmani Jawad F - - 2011
Intracranial aneurysms undergoing balloon-assisted endovascular repair are particularly challenging given the concurrent use of one or more catheters in addition to the primary coiling microcatheter. Here, we describe a previously unreported novel device where a balloon catheter was used as the primary coiling microcatheter, thereby eliminated the need for additional ...
Alsac Jean-Marc - - 2011
BACKGROUND: Aneurysmal and occlusive aortoiliac disease can make the process of introducing large delivery catheters for endovascular repair challenging. We describe the case of a patient who could be treated by a bifurcated stent-graft despite having a unilateral external iliac occlusion. METHODS AND RESULTS: From a brachial access, a covered ...
Williams Paul D - - 2011
Iatrogenic complications present a major challenge to the interventional cardiologist. We describe a case of extensive right coronary artery dissection caused by engagement of a 0.035″ guidewire. Attempts to reopen the flush-occluded posterior descending artery using conventional methods were unsuccessful. However, the vessel was successfully restored with the use of ...
Turkoz Riza - - 2011
Abstract  The increased distance between the coronary ostium and the reimplantation site poses technical challenges in older patients with transposition of the great arteries (TGA) and complex coronary artery anomalies. In this report, we describe a technique for coronary artery reimplantation using a pedicle flap on the pulmonary artery (PA) ...
Grunwald I Q - - 2011
In the last 10 years, CAS became an important alternative to surgery. However, many of the trials regarding stroke prevention had controversial requirements regarding the endovascular approach, leading to questionable conclusions. This review critically addresses results from previous randomized studies on efficacy and safety of the first established therapy for ...
Illoh Kachi - - 2011
In a challenging case of carotid occlusion with slowly evolving stroke, we used brain imaging to facilitate endovascular revascularization resulting in the relief of the patient's symptoms. Patients with carotid occlusion and continued neurological worsening or fluctuations present enormous treatment challenges. These patients may present "slow" strokes with subacute infarcts ...
Kesten F - - 2011
Giant cell arteritis (GCA) is the most common of the vasculitis syndromes and, being a disease of the elderly, its incidence is increasing with the general ageing of the population. GCA is most feared for its early complications, namely blindness and stroke, resulting from inflammation and subsequent occlusion of ocular ...
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