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O'Donovan Clare B CB Institute of Food & Health, University College Dublin (UCD), Belfield, Dublin, - - 2014
Personalised nutrition can be defined as dietary advice that is tailored to an individual. In recent years, the concept of targeted nutrition has evolved which involves delivering specific dietary advice to a group of phenotypically similar individuals or metabotypes. This study examined whether cluster analysis could be used to define ...
Allen Michael S MS Department of Animal Science, Michigan State University, 474 South Shaw Lane, Room 2265A, East Lansing, MI 48824, USA. Electronic address: - - 2014
The objective of this article is to discuss the effects of dietary carbohydrates on energy intake and partitioning as cows progress through lactation. Understanding how diet interacts with the physiologic state as it changes through lactation is critical to maximize productivity, efficiency of production, and health of lactating dairy cows.
Amato Katherine R KR Program in Ecology, Evolution, and Conservation Biology, University of Illinois, Urbana, IL, 61801; Department of Anthropology, University of Colorado, Boulder, CO, - - 2014
In all mammals, growth, development, pregnancy, and lactation increase nutritional demands. Although primate field studies tend to focus on shifts in activity and diet as mechanisms to compensate for these demands, differences in digestive efficiency also are likely to be important. Because the gut microbiota can impact host digestive efficiency, ...
Oetzel Garrett R GR Food Animal Production Medicine Section, Department of Medical Sciences, School of Veterinary Medicine, University of Wisconsin-Madison, 2015 Linden Drive, Madison, WI 53706, USA. Electronic address: - - 2014
Veterinarians serving dairy clients can provide systematic investigations of nutritional problems. The foundation of a nutritional investigation is a careful evaluation of the diet being consumed by the cows. This information is supplemented by herd health and production records, evaluation of the cows (particularly locomotion and body condition scoring), and ...
Cooke Rachel R Centre for Exercise, Nutrition and Health Sciences, School for Policy Studies, University of Bristol, Bristol, - - 2014
The aim of this study was to investigate whether nutrition knowledge and attitudes towards healthy eating are predictors of nutrition label use (NLU) and dietary quality in a diverse sample of University students in the UK. An online cross-sectional survey was conducted in 2013 among 500 students (mean age 24.9 ...
Latney La'Toya L Exotic Companion Animal Medicine and Surgery, University of Pennsylvania Veterinary Teaching Hospital, 3900 Delancey Street, Office 2107, Philadelphia, PA 19104, USA. Electronic address: - - 2014
The study of amphibian nutrition requires a detailed review of species-specific natural prey analysis. Invertebrate nutrient composition has been formally studied for more than 60 years and presents the following conclusions: (1) in general, insects are poor in overall calcium content; (2) larval insects have high fat and protein components; and ...
Al-Harrasi Ahmad A Chair of Oman's Medicinal Plants and Marine Natural Products, University of Nizwa, Nizwa, Oman. Electronic address: - - 2014
To assess the nutritional values and antioxidant analysis of 22 varieties of date palm (Phoenix dactylifera) fruit collected from various regions of the Sultanate of Oman. Nutritional parameters including moisture, fats, fiber, proteins, carbohydrates, and energy value were determined using standard methods of Association of Official Analytical Chemists. The antioxidant ...
Yang Yanbo Y Department of Biochemistry, Memorial University of Newfoundland, St. John's, NL, A1B 3X9, - - 2014
Lipoprotein lipase (LPL) is an extracellular lipase that primarily hydrolyzes triglycerides within circulating lipoproteins. Macrophage LPL contributes to atherogenesis, but the mechanisms behind it are poorly understood. We hypothesized that the products of lipoprotein hydrolysis generated by LPL promote atherogenesis by inhibiting the cholesterol efflux ability by macrophages. To test ...
Calabresi Laura L Centro Grossi Paoletti, Dipartimento di Scienze Farmacologiche e Biomolecolari, Università degli Studi di Milano, Milano, Italy. Electronic address: - - 2014
Plasma high density lipoproteins (HDLs) comprise a highly heterogeneous family of lipoprotein particles, differing in density, size, surface charge, and lipid and protein composition. Epidemiological studies have shown that plasma HDL level inversely correlates with atherosclerotic cardiovascular disease. The most relevant atheroprotective function of HDL is to promote the removal ...
Hernáez Alvaro A From the Cardiovascular Risk and Nutrition Research Group, REGICOR Study Group, CIBER de Fisiopatología de la Nutrición y la Obesidad (CIBEROBN) (A.H., M.F., D.M.-A., A.G.-G., O.D.-G., S.M.-P., M.-I.C., M.F.), Cardiovascular Epidemiology and Genetics Research Group, REGICOR Study Group, CIBER de Epidemiología y Salud Pública (CIBERESP) (I.S.), and Human Pharmacology and Clinical Neurosciences Research Group (R.d.l.T.), IMIM-Research Institute Hospital del Mar, Barcelona, Spain; Ph.D program of Food Sciences and Nutrition (A.H.) and Department of Nutrition and Bromatology, Faculty of Pharmacy (R.M.), Universitat de Barcelona, Barcelona, Spain; Research Unit on Lipids and Atherosclerosis, Hospital Universitari Sant Joan, IISPV, Universitat Rovira I Virgili and CIBER de Diabetes y Enfermedades Metabólicas Asociadas (CIBERDEM), Reus, Spain (S.F.-C., U.C., R.S., A.P.); Ph.D program in Biochemistry, Molecular Biology and Biomedicine, Department of Biochemistry and Molecular Biology, Universitat Autònoma de Barcelona, Barcelona, Spain (M.F.); Institute of Public Health and Clinical Nutrition, University of Eastern Finland, Kuopio, Finland (K.N.); German Institute of Human Nutrition (DIFE), Potsdam-Rehbruecke, Germany (H.-J.F.Z.); and Lipoprotein Metabolism Section, National Heart, Lung and Blood Institute, National Institutes of Health, Bethesda, MD - - 2014
Olive oil polyphenols have shown beneficial properties against cardiovascular risk factors. Their consumption has been associated with higher cholesterol content in high-density lipoproteins (HDL). However, data on polyphenol effects on HDL quality are scarce. We, therefore, assessed whether polyphenol-rich olive oil consumption could enhance the HDL main function, its cholesterol ...
Gefeller E M EM Faculty of Veterinary Medicine, Institute of Veterinary Physiology, Freie Universität Berlin, Berlin, - - 2014
Zinc is effective in the prevention and treatment of post-weaning diarrhoea and in promoting piglet growth. Its effects on the absorption of nutrients and the secretory capacity of the intestinal epithelium are controversial. We investigated the effects of age, dietary pharmacological zinc supplementation and acute zinc exposure in vitro on ...
Yi Haechang H Department of Food Science, Cornell University, Ithaca, NY 14853-7201, USA - - 2014
This study was conducted to assess the effects of flaxseed oil and dried whitebait as a source of ω-3 fatty acids (ω-3 FA), which could be used to produce eggs enriched with ω-3 FA, and of fructo-oligosaccharide (FOS) as a source of prebiotics on performance of hens (commercial Hy-Line Brown ...
Uto-Kondo Harumi H Division of Anti-aging and Vascular Medicine, National Defense Medical College, 3-2 Namiki, Tokorozawa, Saitama 359-8513, - - 2014
Reverse cholesterol transport (RCT) is a mechanism critical to the anti-atherogenic property of HDL. Although citrulline contributes to the amelioration of atherosclerosis via endothelial nitric oxide production, it remains unclear whether it affects RCT. This study was undertaken to clarify the effects of citrulline on expressions of specific transporters such ...
Vilarrasa E E Animal Nutrition and Welfare Service (SNiBA), Department of Animal and Food Science, Facultat de Veterinària, Universitat Autònoma de Barcelona, 08193, Bellaterra, Barcelona, Spain, - - 2014
Re-esterified palm oils are obtained from the chemical esterification of palm acid oils (rich in free fatty acids) with glycerol, both economically interesting by-products from oil refining and biodiesel industries, respectively. Thus, re-esterified palm oils could be an economically interesting alternative to native palm oil in broiler chick diets. However, ...
Tordoff Michael G MG Monell Chemical Senses Center, Philadelphia, PA 19194, USA. Electronic address: - - 2014
Many animals thrive when given a choice of separate sources of macronutrients. How they do this is unknown. Here, we report some studies comparing the spontaneous choices between carbohydrate- and fat-containing food sources of seven inbred mouse strains (B6, BTBR, CBA, JF1, NZW, PWD and PWK) and three mouse models ...
Uto-Kondo Harumi H Division of Anti-aging and Vascular Medicine, Department of Internal Medicine, National Defense Medical College, Tokorozawa, - - 2014
Reverse cholesterol transport (RCT) is pivotal in the return of excess cholesterol from peripheral tissues to the liver for excretion in bile and eventually feces. RCT from macrophages is a critical anti-atherogenicity mechanism of HDL. As the cholesterol absorption inhibitor ezetimibe promoted RCT in mice, which lack cholesterol ester transfer ...
Kuroda Masayuki M From the Department of Genome Research and Clinical Application, Graduate School of Medicine (M.K., S.A., Y.A., H.B.) and Center for Advanced Medicine, Chiba University Hospital (M.K.), Chiba University, Chiba, Japan; Department of Vascular Medicine, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands (A.G.H., E.S.G.S.); Department of Nephrology in Internal Medicine, Kitasato University Hospital, Sagamihara, Japan (K.K.); Department of Internal Medicine and Molecular Science, Osaka University Graduate School of Medicine, Osaka, Japan (S.Y.); Division of Endocrinology and Metabolism, Department of Medicine, Diabetes Center, Jichi Medical University, Tochigi, Japan (S.I.); Chiba University, Chiba, Japan (Y.S.); and Department of Clinical-Laboratory and Experimental-Research Medicine, Toho University Sakura Medical Center, Sakura, Japan - - 2014
In familial lecithin:cholesterol acyltransferase (LCAT) deficiency (FLD), deposition of abnormal lipoproteins in the renal stroma ultimately leads to renal failure. However, fish-eye disease (FED) does not lead to renal damage although the causative mutations for both FLD and FED lie within the same LCAT gene. This study was performed to ...
Muíño Iria I Departamento de Tecnología de Alimentos, Instituto Nacional de Investigación y Tecnología Agraria y Alimentaria (INIA), Carretera de La Coruña, km. 7, Madrid 28040, Spain. Electronic address: - - 2014
Thirty lambs were assigned to the following treatments: control diet (C) rich in omega-3 fatty acids; C plus 900ppm red wine extract (RWE), or C plus 300ppm vitamin E (VE). Oxidative stability and sensory properties of chops stored in MAP (70% O2/30% CO2) during 12days were evaluated. Chops from the ...
Siddiqui Anwar J AJ Department of Laboratory Medicine, Care Sciences and Society (Clinical Geriatrics), Karolinska University Hospital Huddinge and Karolinska Institute, Stockholm, - - 2014
Background: Angiogenesis is usually driven by inflammation. Matrix metalloproteinases MMP-3 and MMP-9 and tissue inhibitors of metalloproteinases TIMP-1 and TIMP-2 are implicated in vascular remodeling. TIMP-2 exhibits antiangiogenic properties. Statins show benefits that are additional to lipid lowering including pro- and antiangiogenic properties. Atherosclerotic lesions in the coronary arteries have ...
Spindler Stephen R SR Department of Biochemistry, University of California at Riverside, Riverside, CA, 92521, USA, - - 2014
Marine oils rich in ω-3 polyunsaturated fatty acids have been recommended as a preventive treatment for patients at risk for cardiovascular diseases. These oils also are the third most consumed dietary supplement in the USA. However, evidence for their health benefits is equivocal. We tested the daily, isocaloric administration of ...
Zhu Cheng-Cheng CC 1 College of Animal Science and Technology, Nanjing Agricultural University, Nanjing 210095, - - 2014
Mycotoxins, such as aflatoxin (AF), fumonisin B1, zearalenone (ZEA), and deoxynivalenol (DON), are commonly found in many food commodities. Mycotoxins have been shown to increase DNA methylation levels in a human intestinal cell line. We previously showed that the developmental competence of oocytes was affected in mice that had been ...
Cui Zhong-Kai ZK Department of Chemistry, Centre for Self-Assembled Chemical Structures (CSACS), Université de Montréal, C.P. 6128, Succ. Centre Ville, Montréal, Québec H3C 3J7, Canada. Electronic address: - - 2014
Liposomes made of single-chain amphiphiles and a large amount of sterols display several advantages including a limited permeability. In the present paper, we examine the possibility to prepare such non-phospholipid liposomes with interfacial polyethylene glycol (PEG) in order to improve their circulation in the blood stream. Cholesterol (Chol) was chosen ...
Henning Susanne M - - 2014
The antioxidant activity (AA) of fruits and vegetables has been thoroughly investigated but less is know about the AA of dietary supplements (DS). We therefore assessed the AA of 3-5 DS each from pomegranate, milk thistle, green tea, grapes, goji and acai using four widely used standard methods. The secondary ...
Chen Juan J Zhej iang Chinese Medical Universi ty, Hangzhou 310053, P. R. China. Electronic address: - - 2014
Danhong injection (DHI), a Chinese medical product extracted from Radix et Rhizoma Salviae Miltiorrhizae (Salvia miltiorrhiza Bge., Labiatae, Danshen in Chinese) and Flos Carthami (Carthamus tinctorius L., Compositae, Honghua in Chinese), has been reported to have anti-inflammatory, anti-oxidative and anti-fibrinolytic properties and is used extensively for the clinical treatment of ...
Yang Jun J Frito-Lay R&D, 7701 Legacy Drive, Plano, TX 75024, USA. Electronic address: - - 2014
Dietary fibres (DFs) from yellow soybean hulls (Glycine max) were developed by mimicking pH in the human digestive system. Using both traditional AOAC991.43 and newly developed AOAC2011.25 methods, DFs were quantified, and their physicochemical properties were characterised by determining colour, particle size, water absorption and solubility capacity. Viscoelastic properties of ...
Rached Fabiana H FH 1] National Institute for Health and Medical Research (INSERM), UMR-ICAN 1166; Université Pierre et Marie Curie-Paris 6; AP-HP, Pitié-Salpétrière University Hospital; ICAN, Paris, France [2] Heart Institute-InCor, University of Sao Paulo Medical School Hospital, Sao Paulo, - - 2014
Cardiovascular diseases (CVD) are the leading cause of morbi-mortality worldwide. Dyslipidemia is a major risk factor for premature atherosclerosis and CVD. Lowering LDL-cholesterol levels is well established as an intervention for reduction of CVD. Statins are first-line drugs for treatment of dyslipidemia, but do not address all CVD risk. Development ...
Inglingstad R A RA Department of Chemistry, Biotechnology and Food Science, Norwegian University of Life Sciences, PO Box 5003, NO-1432 Ås, Norway. Electronic address: - - 2014
Two different types of pasture (cultivated and rangeland) and 2 different hay qualities (high and low quality) were examined for their effects on goat milk composition and rennet coagulation properties. Furthermore, the effect of dietary treatments in both the early and late grazing season was studied. As lactation stage is ...
Busso Dolores D Department of Gastroenterology, Faculty of Medicine, Pontificia Universidad Católica. Avda. Bernardo O'Higgins 340. 8331150 Santiago, - - 2014
The cholesterol content of the sperm membrane is regulated during both maturation in the epididymis and capacitation in the female tract, two processes required for the spermatozoa to acquire their fertilising ability. Because Niemann-Pick disease, type C2 (NPC2) protein is one of the most abundant components of the epididymal fluid ...
Kwakernaak Arjan J AJ Department of Endocrinology, University of Groningen, University Medical Center Groningen, Groningen, The - - 2014
Proprotein convertase subtilisin-kexin type 9 (PCSK9) is a key regulator of low density lipoprotein (LDL) receptor processing, but the PCSK9 pathway may also be implicated in the metabolism of triglyceride-rich lipoproteins. Here we determined the relationship of plasma PCSK9 with very low density lipoprotein (VLDL) and LDL subfractions. The relationship ...
Zhao Shiqiang - - 2014
Akebia trifoliata var. australis seed oil (ASO) was used as an edible oil in China. However, in-depth research studies on ASO have yet to be conducted for production of plastic fats in food industry. In this work, an immobilized lipase from Thermomyces lanuginosus (TL IM) was employed to lipase-catalyzed interesterification ...
Bargut Thereza C Lonzetti TC Laboratorio de Morfometria, Metabolismo e Doença Cardiovascular, Centro Biomedico Instituto de Biologia, Universidade Do Estado Do Rio de Janeiro, Av 28 de Setembro 87 Fds, Rio de Janeiro, RJ, - - 2014
Here, we investigate whether a diet rich in fish oil can lead to the development of hepatic alterations associated with non-alcoholic fatty liver disease (NAFLD). To achieve this goal, we provided, for 8 weeks, four different diets to 3-month-old C57BL/6 mice: (a) standard-chow diet (SC; 40 g soybean oil/kg diet, 10 % of ...
Yi Tian T Key Laboratory of Environment Correlative Dietology, Ministry of Education, Huazhong Agricultural University , Wuhan, Hubei , - - 2014
Abstract Orange by-products from juice extraction are generally discarded or used in animal feed due to their low market value. However, orange by-products show potential as dietary fiber (DF) and fat replacers in products such as yogurt. This study assessed the benefits of using orange by-products in DF-enriched materials such ...
Aidoud A A Department of Biology, Faculty of Life and Nature Sciences, Ziane Achour University, Djelfa, - - 2014
Lycopene has the highest antioxidant activity within carotenoids and is an effective free radical scavenger. Virgin olive oil (VOO) and argan oil (AO) contain trace amounts of a wide variety of phytochemicals which have desirable nutritional properties. The present study intended to assess the effect of various dietary VOO and ...
Wipperman Matthew F MF Department of Chemistry, Stony Brook University , Stony Brook, NY , - - 2014
The ability of science and medicine to control the pathogen Mycobacterium tuberculosis (Mtb) requires an understanding of the complex host environment within which it resides. Pathological and biological evidence overwhelmingly demonstrate how the mammalian steroid cholesterol is present throughout the course of infection. Better understanding Mtb requires a more complete ...
Moldal Torfinn - - 2014
Fish meal and fish oil are increasingly replaced by ingredients from terrestrial sources in the feeds for farmed salmonids due to expanding production and reduced availability of marine feed raw material. Fish oil that is rich in n-3 polyunsaturated fatty acids is considered beneficial to human health in general and ...
Sun Dandan D State Key Laboratory of Bioelectronics, Jiangsu key Laboratory for Biomaterials and Devices, School of Biological Science & Medical Engineering, Southeast University, Nanjing, 210096, People's Republic of China. - - 2014
Cholesterol plays an important role in regulating the structural properties of phospholipid membranes and further influences the permeability of molecules and nanoparticles. However, nanoparticles' translocation across phospholipid membranes in the presence of cholesterol on the molecular scale is rarely studied. Here, we performed coarse-grained molecular dynamics simulations to probe the ...
Oravec Stanislav - - 2014
The electrophoretic separation of lipoproteins on polyacrylamide gels enables the quantification of non-atherogenic and atherogenic plasma lipoproteins including small dense low density lipoprotein (sdLDL) particles, which represent the atherogenic lipoprotein subpopulations in plasma. This methodology could help distinguish between non-atherogenic hyperlipidemia, normolipidemia with an atherogenic lipoprotein profile, non-atherogenic normolipidemia, and ...
Böcking Christian C Institute for Laboratory Medicine, Pathobiochemistry and Molecular Diagnostics, Philipps University of Marburg, Marburg, - - 2014
Background: Cross-sectional epidemiological studies have demonstrated that farm milk from traditional farm settings possesses allergoprotective properties. Up to now, it has not been clarified which milk ingredient is responsible for protection against allergic diseases. As farm milk is rich in conjugated linoleic acids (CLA), it is hypothesized that this n-3 ...
Zhou Gang G Discovery and Preclinical Sciences, Merck Research Laboratories , 126 East Lincoln Avenue, Rahway, New Jersey 07065, United - - 2014
Diacylglycerol acyltransferase 1 (DGAT1) presents itself as a potential therapeutic target for obesity and diabetes for its important role in triglyceride biosynthesis. Herein we report the rational design of a novel class of DGAT1 inhibitors featuring a benzomorpholine core (23n). SAR exploration yielded compounds with good potency and selectivity as ...
Wanders Anne J AJ Division of Human Nutrition, Wageningen University, Bomenweg, 2, 6703 HD Wageningen, the - - 2014
An increased intake of dietary fiber has been associated with reduced appetite and reduced energy intake. Research on the effects of seemingly identical classes of dietary fiber on appetite has, however, resulted in conflicting findings. The present study investigated the effects of different fiber properties, including methods of supplementation, on ...
Dikkers Arne A University Medical Center Groningen, - - 2014
Since apolipoprotein (apo) B-containing lipoproteins are pro-atherogenic and their secretion by liver and intestine largely depends on microsomal triglyceride transfer protein (MTP) activity, MTP inhibition strategies are actively pursued. How decreasing the secretion of apoB-containing lipoproteins affects intracellular re-routing of cholesterol is unclear. Therefore, the aim of the present study ...
Chuang Jen-Chieh JC Departments of Internal Medicine, University of Texas Southwestern Medical Center, 5323 Harry Hines Boulevard, Dallas, TX, United States. Electronic address: - - 2014
The small intestine plays a fundamentally important role in regulating whole body cholesterol balance and plasma lipoprotein composition. This is articulated through the interplay of a constellation of genes that ultimately determines the net amount of chylomicron cholesterol delivered to the liver. Major advances in our insights into regulation of ...
Meljon Anna A Institute of Mass Spectrometry, College of Medicine, Swansea University, Singleton Park, Swansea, SA2 8PP, - - 2014
Oxysterols are oxidised forms of cholesterol or its precursors. In this study we utilised the cholesterol 24-hydroxylase knockout mouse (Cyp46a1-/-) to study the sterol and oxysterol content of brain. Despite a great reduction in the abundance of 24S-hydroxycholesterol, the dominant metabolite of cholesterol in wild type brain, no other cholesterol ...
Rønholt Stine S Department of Food Science, Faculty of Science, University of Copenhagen, Rolighedsvej 30, DK-1958 Frederiksberg C, - - 2014
Milk fat exists as globules in its natural state in milk. The potential of using globular fat to modulate the rheological properties and crystallization behavior in butter-like emulsions was studied in the present work. We conducted a comparative study of butter-like emulsions, with a fat phase consisting of 0, 10, ...
Ramprasath Vanu R - - 2014
Nichols et al. (Lipids Health Dis 13:2, 2014) raised concern about the higher n-6 concentration in fish oil used in our recent study which is different from typical commercial fish oils (Ramprasath et al. Lipids Health Dis 12:178, 2013). The aim of our study was to compare the effect of ...
Daniels Jane-Ann - - 2014
High density lipoproteins (HDL) have many cardioprotective roles; however, in subjects with type 2 diabetes (T2D) these cardioprotective properties are diminished. Conversely, increased fruit and vegetable (F&V) intake may reduce cardiovascular disease risk, although direct trial evidence of a mechanism by which this occurs in subjects with T2D is lacking. ...
Mora-Gallego Héctor H IRTA, XaRTA, Food Technology, Finca Camps i Armet, s/n, E-17121 Monells, Girona, - - 2014
The effect of pork fat reduction (from 44% to 20% final fat content) and its partial substitution by sunflower oil (3% addition) on the physicochemical, instrumental and sensory properties throughout storage time of small caliber non-acid fermented sausages (fuet type) with reduced sodium content (with partial substitution of NaCl by ...
Eskens Bart J M BJ Department of Physiology, Cardiovascular Research Institute Maastricht (CARIM), Maastricht University, Maastricht, The - - 2014
While previous studies have indicated an important role for the endothelial glycocalyx in regulation of microvascular function, it was recently shown that acute enzymatic glycocalyx degradation in rats was associated with an impaired insulin-mediated glucose disposal. The aim of this study was to determine whether glycocalyx damage in skeletal muscle ...
Rye Kerry-Anne KA From the Lipid Research Group, Centre for Vascular Research, Lowy Center, University of New South Wales, Sydney, New South Wales, - - 2014
There is compelling evidence from human population studies that plasma levels of high-density lipoprotein (HDL) cholesterol correlate inversely with cardiovascular risk. Identification of this relationship has stimulated research designed to understand how HDL metabolism is regulated. The ultimate goal of these studies has been to develop HDL-raising therapies that have ...
Mohamed Roslan Nur Illiyin NI Halal Products Research Institute, Universiti Putra - - 2014
A study was carried out to compare the composition and thermal properties of lard (LD) and engkabang fat (EF) - canola oil (CaO) blend interesterified with Candida antartica lipase (C. antartica). A fat blend EF-4 (40% EF in CaO) was prepared and interesterified using C. antartica lipase at 60°C for ...
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