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Chen Jin-Ran JR Arkansas Children's Nutrition Center (J.R.C., O.P.L, M.L.B., T.M.B., M.J.J.R.), Little Rock, AR 72202, - - 2014
Chronic consumption by experimental animals of a typical Western diet high in saturated fats and cholesterol during postnatal life has been demonstrated to impair skeletal development. However, underlying mechanism by which high fat, energy dense diets affect bone forming cell phenotypes is poorly understood. Here, we show that male weanling ...
Crosse M M 1Teagasc,Animal & Grassland Research and Innovation Centre,Moorepark,Fermoy,Co. - - 2014
The objective of this study was to investigate the immediate and carryover effects of imposing two post-grazing sward heights (PGSH) for varying duration during early lactation on sward characteristics and dairy cow production. The experiment was a randomised block design with a 2×2 factorial arrangement of treatments. A total of ...
Smith Geoff M GM MONREPOS Archaeological Research Centre and Museum for Human Behavioural Evolution, RGZM, Schloss Monrepos, 56567 Neuwied, Germany. Electronic address: - - 2014
The recurrent presence at Middle Palaeolithic sites of megafaunal remains, such as mammoth, elephant and rhinoceros, together with isotope analyses signalling meat as a prominent protein source, have been used to argue that these species played a central role in Neanderthal diet. Key to this model are the bone heap ...
Murzaku Era Caterina EC Department of Dermatology, Robert Wood Johnson Medical School, Rutgers University, New Brunswick, New - - 2014
The roles of dietary factors in aggravating, preventing, or treating skin diseases are common questions encountered in dermatology practice. Part II of this two-part series reviews dietary modifications that can potentially be utilized in the management of melanoma, chronic urticaria, and psoriasis patients. Specifically, we examine the effect of alcohol ...
Wang Shuhui S Department of Cellular and Molecular Medicine, Cleveland Clinic, Cleveland, - - 2014
ABCA1 mediates the secretion of cellular free cholesterol and phospholipids to an extracellular acceptor, apolipoprotein AI, to form nascent high-density lipoprotein (HDL). Thus, ABCA1 is a key molecule in cholesterol homeostasis. Functional studies of certain Tangier disease mutations demonstrate that ABCA1 has multiple activities, including plasma membrane remodeling and apoAI ...
Friedauer K K Physiology and Hygiene Group, Institute of Animal Science, University of Bonn, Bonn, - - 2014
Early lactating cows mobilize adipose tissue (AT) to provide energy for milk yield and maintenance and are susceptible to metabolic disorders and impaired immune response. Conjugated linoleic acids (CLA), mainly the trans-10, cis-12 isomer, reduce milk fat synthesis and may attenuate negative energy balance. Circulating glucocorticoids (GC) are increased during ...
Ziener Martine L - - 2014
BackgroundTreatment of symmetrical onychomadesis (symmetrical lupoid onychodystrophy) is a challenging task for dermatologists. The acute phase is characterized by sloughing of claw plates and loose claws have to be removed and secondary infections treated. The goal of long-term treatment is to allow claws to re-grow with normal quality and to ...
Rieger Johannes J Dr. Senckenberg Institute of Neurooncology, University Hospital Frankfurt, D-60528 Frankfurt, - - 2014
After the publication of the article, the authors noted that they had made an error regarding certain data in the Results section. On page 1848 the sentence 'Thirteen of these received no salvage treatment' should be replaced by 'Nine of these stopped the diet'. The previous statement was erroneously inserted. ...
Yanagisawa Daijiro D Molecular Neuroscience Research Center, Shiga University of Medical Science, Otsu, - - 2014
Recent evidence supports the amyloid cascade hypothesis that a pathological change of amyloid β (Aβ) in the brain is an initiating event in Alzheimer's disease (AD). Accordingly, modulating the abnormal Aβ aggregation is considered a potential therapeutic target in AD. Curcumin, a low-molecular-weight polyphenol derived from the well-known curry spice ...
Stefler D D Department of Epidemiology and Public Health, University College London, London, - - 2014
Unhealthy diet has been proposed as one of the main reasons for the high mortality in Central and Eastern Europe (CEE) and the former Soviet Union (FSU) but individual-level effects of dietary habits on health in the region are sparse. We examined the associations between the healthy diet indicator (HDI) ...
Silbernagel Günther G Department of Angiology, Swiss Cardiovascular Center, Inselspital, University of Bern, Bern, Switzerland; - - 2014
High concentrations of HDL cholesterol are considered to indicate efficient reverse cholesterol transport and to protect from atherosclerosis. However, HDL has been suggested to be dysfunctional in ESRD. Hence, our main objective was to investigate the effect of HDL cholesterol on outcomes in maintenance hemodialysis patients with diabetes. Moreover, we ...
Rizkalla Salwa W SW aInstitute of Cardiometabolism and Nutrition(ICAN), Assistance Publique-Hôpitaux de Paris, and Human Nutrition Research Center-Ile de France, Hôpital Pitié-Salpêtrière, Paris, F-75013, France bINSERM, UMRS U1166 (Eq 6) Nutriomics UPMC, Sorbonne University, Pierre et Marie Curie-Paris 6, Paris 75006 - - 2014
The role of glycemic index on metabolic and cardiovascular risk factors received considerable attention in light of the current increase in cardiometabolic disorders. We aimed to deal and identify the recently published prospective epidemiological studies as well as randomized controlled studies investigating the associations of metabolic and cardiovascular risk markers ...
Liu Yun-Zi - - 2014
Prolonged stress leads over time to allostatic load on the body and is likely to exacerbate a disease process. Long-term of stress exposure is one of a risk factor for metabolism-related diseases such as obesity and type 2 diabetes. However, the relationship between chronic stress and non-alcoholic fatty liver disease ...
Casas-Agustench Patricia - - 2014
Combining multiple genetic variants related to obesity into a genetic risk score (GRS) might improve identification of individuals at risk of developing obesity. Moreover, characterizing gene-diet interactions is a research challenge to establish dietary recommendations to individuals with higher predisposition to obesity. Our objective was to analyze the association between ...
Zhu Chen-Tseh CT Department of Ecology and Evolutionary Biology, Brown University, Providence, Rhode Island, United States of - - 2014
Dietary restriction (DR) is the most consistent means of extending longevity in a wide range of organisms. A growing body of literature indicates that mitochondria play an important role in longevity extension by DR, but the impact of mitochondrial genotypes on the DR process have received little attention. Mitochondrial function ...
Balsevich Georgia G G Balsevich, Stress Neurobiology and Behavioural Neurogenetics, Max Planck Insitute of Psychiatry, Munich, - - 2014
While it is known that stress promotes obesity, the effects of stress within an obesogenic context are largely unclear and molecular targets at the interface remain elusive. The FK506 binding protein 51 (FKBP51, gene: Fkbp5) has been identified as a target gene implicated in the development of stress-related psychiatric disorders, ...
Wählby Carolina C Centre for Image Analysis and Science for Life Laboratory, Uppsala University, Uppsala, Sweden; Imaging Platform, Broad Institute of Harvard and MIT, Cambridge, MA, USA. Electronic address: - - 2014
Fat accumulation is a complex phenotype affected by factors such as neuroendocrine signaling, feeding, activity, and reproductive output. Accordingly, the most informative screens for genes and compounds affecting fat accumulation would be those carried out in whole living animals. Caenorhabditis elegans is a well-established and effective model organism, especially for ...
Welty Francine K FK Beth Israel Deaconess Medical Center, Boston, Massachusetts, - - 2014
Several mutations in the apoB, proprotein convertase subtilisin/kexin type 9 (PCSK9), and MTP genes result in low or absent levels of apoB and LDL-cholesterol in plasma, which cause familial hypobetalipoproteinemia and abetalipoproteinemia. Mutations in the ANGPTL3 gene cause familial combined hypolipidemia. Clinical manifestations range from none to severe, debilitating, and ...
Aschbacher Kirstin K Department of Psychiatry, University of California, San Francisco, CA, United States; The Institute for Integrative Health, Baltimore, MD, United States. Electronic address: - - 2014
In preclinical studies, the combination of chronic stress and a high sugar/fat diet is a more potent driver of visceral adiposity than diet alone, a process mediated by peripheral neuropeptide Y (NPY). In a human model of chronic stress, we investigated whether the synergistic combination of highly palatable foods (HPF; ...
Liu Zhenglong Z State Key Laboratory of Molecular Developmental Biology, Institute of Genetics and Developmental Biology, Chinese Academy of Sciences, Beijing 100101, China; University of the Chinese Academy of Sciences, Beijing 100049, - - 2014
Fat storage disorders including obesity are pandemic human health problems. As a genetically amenable model organism, Caenorhabditis elegans has often been used to explore the molecular mechanisms of fat storage regulation. Dye staining of fixed animals and stimulated Raman scattering (SRS) microscopy methods have been used successfully to study fat ...
Harris William S WS Health Diagnostic Laboratory, Inc., 737 N. 5th St, Suite 103, Richmond, VA, 23219, USA, - - 2014
Earlier reports indicated that patients with the apolipoprotein APOE ε4 allele responded to fish oil supplementation with a rise in serum low-density lipoprotein cholesterol (LDL-C) compared to ε3 homozygotes. In this study, we used clinical laboratory data to test the hypothesis that the cross-sectional relation between RBC omega-3 fatty acid ...
Dutta Mousumi M Oxidative Stress and Free Radical Biology Laboratory, Department of Physiology, University of Calcutta, University College of Science and Technology, 92, APC Road, Kolkata 700 009, INDIA.; Department of Physiology, Vidyasagar College, Kolkata 700 006, - - 2014
Arsenic is a well known global groundwater contaminant. Exposure of human body to arsenic causes various hazardous effects via oxidative stress. Nutrition is an important susceptible factor which can affect arsenic toxicity by several plausible mechanisms. Development of modern civilization led to alteration in the lifestyle as well as food ...
Boersma Gretha J GJ Department of Psychiatry and Behavioral Sciences, Johns Hopkins University, School of Medicine, Baltimore, MD, - - 2014
Both prenatal stress exposure and a passive stress coping style have been identified as risk factors for insulin resistance in rats. In the current study, we test the hypothesis that PNS and stress coping style may interact in predicting susceptibility for metabolic disease. To test this hypothesis, adult male control ...
Thomsen Mette M Department of Clinical Biochemistry, Herlev Hospital, Copenhagen University Hospital, Copenhagen, - - 2014
Increased nonfasting plasma triglycerides marking increased amounts of cholesterol in remnant lipoproteins are important risk factors for cardiovascular disease, but whether lifelong reduced concentrations of triglycerides on a genetic basis ultimately lead to reduced all-cause mortality is unknown. We tested this hypothesis.METHODS: Using individuals from the Copenhagen City Heart Study ...
Kalantarian Shadi S Department of Epidemiology, Harvard School of Public Health, Boston, MA. Electronic address: - - 2014
Previous studies observed the surprising finding that saturated fat was inversely associated with atherosclerosis progression in postmenopausal women, whereas polyunsaturated fat (PUFA) and carbohydrates were positively associated. Whether certain genes modify the association of diet with atherosclerotic progression is unknown. Using Haplotype-tagging single nucleotide polymorphisms, we evaluated gene-diet interactions with ...
- - 2014
[This corrects the article DOI: 10.1371/journal.pone.0051357.].
Zhang Zili Z State Key Laboratory of Respiratory Diseases, Guangzhou Institute of Respiratory Disease, The First Affiliated Hospital, Guangzhou Medical University, Guangzhou, Guangdong, - - 2014
Low plasma level of high density lipoprotein cholesterol (HDL-c) was an independent risk factor for cardio vascular disorder, and associated with poor outcomes in pulmonary arterial hypertension. To compare the effects of vegetarian diets and omnivorous diets on HDL-c in plasma, we identified cross-sectional and cohort studies related to HDL-c ...
Rowan Sheldon S JM-USDA Human Nutrition Research Center on Aging (HNRCA), Tufts University, Boston, - - 2014
Age-related macular degeneration (AMD) is a leading cause of visual impairment worldwide. Genetics and diet contribute to the relative risk for developing AMD, but their interactions are poorly understood. Genetic variations in Complement Factor H (CFH), and dietary glycemic index (GI) are major risk factors for AMD. We explored the ...
- - 2014
[This corrects the article DOI: 10.1371/journal.pone.0088349.].
- - 2014
[This corrects the article DOI: 10.1371/journal..].
Hannaoui Samia S Department of Ecosystem and Public Health, Faculty of Veterinary Medicine, and Hotchkiss Brain Institute, University of Calgary, 3280 Hospital Drive Northwest, Calgary, AB T2N 4Z6, Canada. - - 2014
Prion diseases are transmissible and fatal neurodegenerative disorders of humans and animals. They are characterized by the accumulation of PrPSc, an aberrantly folded isoform of the cellular prion protein PrPC, in the brains of affected individuals. PrPC is a cell surface glycoprotein attached to the outer leaflet of the plasma ...
- - 2014
[This corrects the article DOI: 10.1371/journal.pone.0097968.].
- - 2014
[This corrects the article DOI: 10.1371/journal.pone.0040398.].
Javelot H H Laboratoire de Nutrition Génétique et Exposition aux Risques Environnementaux, INSERM U954, Faculté de Médecine de Nancy-UHP, Vandœuvre-lès-Nancy, France; ETAP-Applied Ethology-Neuropsychopharmacology department, Vandœuvre-lès-Nancy, France; Clinical Pharmacy Service-Mental Health Establishment (EPSAN), Brumath, France. Electronic address: - - 2013
Methyl donor deficiencies and chronic stress cause depression independently, but their interaction has never been thoroughly evaluated. In our study, methyl donor deficient diet and chronic stress condition consisted respectively of a B2, B9, B12, and choline-free diet and a chronic mild stress procedure. Rats were randomly assigned to six ...
Manios Y - - 2013
The Healthy Lifestyle-Diet Index (HLD-index), previously developed to assess the degree of adherence to dietary and lifestyle guidelines for primary schoolchildren, was revised according to updated recommendations. Τhe association of the revised HLD-index (R-HLD-index) with obesity and iron deficiency (ID) was also examined. A representative sample of 2660 primary schoolchildren ...
Savietto D - - 2013
To better understand the mechanisms that allow some animals to sustain their productive effort in harsh environmental conditions, rabbit does from two selection lines (LP and V) were housed in normal (NC), nutritional (NF) or heat (HC) challenging environmental conditions from first to third partum. The LP line (n=85) was ...
Boddu Neeraja J NJ The Central Arkansas Veterans Healthcare System; Little Rock, AR - - 2014
Objective To study whether there is an association between adiponectin and endoplasmic reticulum/sarcoplasmic reticulum (ERSR) stress. Research design Eleven-month-old male wild-type (WT) and adiponectin knockout (ADKO) mice were placed on chow or high fat diet for 12 weeks. The changes in ER stress and inflammatory genes were determined in the ...
Moynihan James - - 2013
This brief document outlines reasons for expecting that diets which cause gout should help prevent multiple sclerosis relapses.
Zamora-Ros Raul - - 2013
Dietary flavonoids and lignans may protect against several chronic diseases, but there is little evidence on the relationship between flavonoid and lignan intake and mortality. We investigated the association between both all-cause and specific-cause mortality and intake of flavonoids and lignans in the Spanish European Prospective Investigation into Cancer and ...
Fleming Patrick - - 2013
Dietary glycaemic index (GI) is a measure of the postprandial glycaemic response to carbohydrates. Observational studies have found increased triglycerides and decreased high-density lipoprotein levels in patients consuming higher GI foods. Our aim was to review and synthesize the evidence on the effect of low-glucose index diets on serum lipid ...
Kang Seok Hui - - 2013
The aim of this study is to evaluate changes in body composition in accordance with residual renal function (RRF). Two hundred forty-four patients with more than 1 year of follow-up were enrolled. The mean value of RRF at peritoneal dialysis (PD) initiation and 1 year after PD initiation was used ...
Schwingshackl L - - 2013
The aim of the present meta-analysis was to investigate the long-term effects of glycemic index-related diets in the management of obesity with a special emphasis on the potential benefits of low glycemic index/load (GI/GL) in the prevention of obesity-associated risks. Electronic searches for randomized controlled trials (RCTs) comparing low glycemic ...
Petäjä Elina M - - 2013
Objective: Adipocyte hypertrophy has been suggested to be causally linked with inflammation and systemic insulin resistance. The aim of the study was to determine whether increased adipocyte size is associated with increased liver fat content due to nonalcoholic fatty liver disease (NAFLD) in humans independent of obesity, fat distribution and ...
Cuenca-García Magdalena - - 2013
OBJECTIVE: To explore the clustering of different lifestyle behaviors and whether this clustering differs by gender, age, and health-related fitness. DESIGN: Healthy Lifestyle in Europe by Nutrition in Adolescence (HELENA) cross-sectional study. SETTING: Ten European cities. PARTICIPANTS: A total of 2,084 adolescents (12.5-17.5 years). MAIN OUTCOME MEASURES: Four lifestyle behaviors ...
Ribeiro Marinei Cristina Pereira - - 2013
This study was designed to develop a rodent model of hydrochlorothiazide (HCTZ) toxicity by associating its intake with a high-fat (HF) diet. Rats were fed for 16 weeks with a control diet or with an HF diet supplemented or not with different doses of HCTZ. HCTZ, in a similar way ...
Fernandes Rômulo A - - 2013
BACKGROUND: In pediatric populations, the use of resting heart rate as a health index remains unclear, mainly in epidemiological settings. The aims of this study were to analyze the impact of resting heart rate on screening dyslipidemia and high blood glucose and also to identify its significance in pediatric populations. ...
Kim Jung Eun - - 2013
[This corrects the article on p. 113 in vol. 6, PMID: 22586499.].
Kim Daniel S DS Department of Medicine, Division of Medical Genetics, University of Washington School of Medicine, Seattle, WA, - - 2013
Cardiovascular disease (CVD) is the leading cause of death in developed countries. Plasma cholesterol level is a key risk factor in CVD pathogenesis. Genetic and dietary variation both influence plasma cholesterol; however, little is known about dietary interactions with genetic variants influencing the absorption and transport of dietary cholesterol. We ...
Medina Marisa W - - 2013
[This corrects the article on p. e1003058 in vol. 8.].
El-Deeb Wael M - - 2013
A total of 50 does were used to determine selected hematological and biochemical parameters with special references to oxidative stress markers, acute phase protein profiles, and proinflammatory cytokines in healthy and gangrenous mastitis affected does. Animals were divided into two equal groups represented as clinically healthy (control) and diseased groups, ...
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