Search Results
Results 1 - 50 of 1807
1 2 3 4 5 6 7 8 9 10 >
Kim D H DH 1Department of Animal and Food Sciences,University of Kentucky,Lexington,KY - - 2014
The objective was to investigate the effect of intake before fasting on concentrations of metabolites and hormones, respiratory quotient (RQ) and fasting heat production (HP) using the washed rumen technique and to compare these values with those from the fed state. Six Holstein steers (360±22 kg) were maintained at 21°C ...
Xu C Z CZ College of Animal Science and Technology, Zhejiang A & F University, Lin'an 311300, P. R. - - 2014
This experiment was conducted to determine the influences of supplementing different levels of an additive containing lutein in the diet of Chinese Holstein lactating cows on production performance, antioxidative plasma metabolites, and milk quality. This study was performed on 60 multiparous Holstein dairy cows in peak lactation. The cows were ...
Yang Nan N N Yang, Medicine, University of Manchester, Manchester, United - - 2014
Glucocorticoids (Gc) are the most potent anti-inflammatory agents known and are in wide clinical use. We have previously shown that increased serum concentration significantly attenuates regulation of a simple Gc-responsive reporter. We now find that GR regulation of some endogenous transactivated, but not transrepressed genes is impaired, suggesting template specificity. ...
O'Byrne Sheila M SM Department of Medicine, College of Physicians and Surgeons, Columbia University, New York, NY 10032, - - 2013
By definition, a vitamin is a substance that must be obtained regularly from the diet. Vitamin A must be acquired from the diet, but unlike most vitamins, it can also be stored within the body in relatively high levels. For humans living in developed nations or animals living in present-day ...
Takahashi Shigeru - - 2012
Parotid glands of experimental animals fed a liquid diet are reported to show atrophy (Hall and Schneyer 1964; Wilborn and Schneyer 1970; Hand and Ho 1981; Scott et al. 1990; Scott and Gunn 1991). To clarify whether apoptosis and proliferation of acinar cells participate in atrophy of rat parotid glands ...
Lodhi Irfan J IJ Division of Endocrinology, Metabolism & Lipid Research, Washington University School of Medicine, St. Louis, MO 63110, - - 2012
De novo lipogenesis in adipocytes, especially with high fat feeding, is poorly understood. We demonstrate that an adipocyte lipogenic pathway encompassing fatty acid synthase (FAS) and PexRAP (peroxisomal reductase activating PPARγ) modulates endogenous PPARγ activation and adiposity. Mice lacking FAS in adult adipose tissue manifested increased energy expenditure, increased brown ...
Kozuka Chisayo C Division of Endocrinology, Diabetes and Metabolism, Hematology, Rheumatology (Second Department of Internal Medicine), Graduate School of Medicine, University of the Ryukyus, Okinawa, - - 2012
Brown rice is known to improve glucose intolerance and prevent the onset of diabetes. However, the underlying mechanisms remain obscure. In the current study, we investigated the effect of brown rice and its major component, γ-oryzanol (Orz), on feeding behavior and fuel homeostasis in mice. When mice were allowed free ...
Kawai Daisuke - - 2012
Oxidative stress is a strong contributor to the progression from simple fatty liver to nonalcoholic steatohepatitis (NASH). Molecular hydrogen is an effective antioxidant that reduces cytotoxic reactive oxygen species. In this study, we investigated the effects of hydrogen-rich water and the drug pioglitazone on the progression of NASH in mouse ...
Camacho Alberto A University of Cambridge Metabolic Research Laboratories, NIHR Cambridge Biomedical Research Centre Institute of Metabolic Science, Addenbrooke's Hospital, Cambridge, UK. - - 2012
Mitochondria dysfunction contributes to the pathophysiology of obesity, diabetes, neurodegeneration and ageing. The peroxisome proliferator-activated receptor-gamma coactivator-1β (PGC-1β) coordinates mitochondrial biogenesis and function as well as fatty acid metabolism. It has been suggested that endoplasmic reticulum (ER) stress may be one of the mechanisms linking mitochondrial dysfunction and these pathologies. ...
Kockx Maaike - - 2012
Cholesterol excess is typical of various diseases including atherosclerosis. We have investigated whether cholesterol accumulation in the endoplasmic reticulum (ER) can inhibit exit of vesicular cargo and secretion of proteins by studying apolipoprotein E (apoE), a significant glycoprotein in human health and disease. Chinese Hamster Ovary cells expressing human apoE ...
Femia Angelo Pietro - - 2012
Inflammation may increase cancer risk, therefore, we studied whether polyphenol-rich Marie Ménard (MM) apples with reported anti-inflammatory activity prevent 1,2-dimethylhydrazine (DMH)-induced colon carcinogenesis in rats and, likewise whether high-fat (HF) diet promoting carcinogenesis, may affect inflammation. DMH-induced rats were fed for 15 weeks with: an HF diet (23% corn oil ...
White Patrick B - - 2012
BACKGROUND: Obesity accelerates pancreatic cancer growth; the mechanisms underlying this association are poorly understood. This study evaluated the hypothesis that obesity, rather than high-fat diet, is responsible for accelerated pancreatic cancer growth. METHODS: Male C57BL/6J mice were studied after 19 weeks of high-fat (60 % fat; n = 20) or low-fat (10 % fat; n = 10) ...
Oashi Kohei - - 2012
BACKGROUND: Microsurgical transfer of the vascularised fat flaps has become a well-established method for soft-tissue augmentation because it has been believed to provide the restoration of symmetry without atrophy. Yet little has been reported on the long-term fate of the vascularised fat flaps. The purpose of this study was to ...
Lu Yao-Ping YP Susan Lehman Cullman Laboratory for Cancer Research, Department of Chemical Biology Ernest Mario School of Pharmacy, Rutgers, The State University of New Jersey, Piscataway, NJ 08854, USA. - - 2012
Removal of the parametrial fat pads (partial lipectomy) from female SKH-1 mice fed a high-fat diet inhibited UVB-induced carcinogenesis, but this was not observed in mice fed a low-fat chow diet. Partial lipectomy in high-fat-fed mice decreased the number of keratoacanthomas and squamous cell carcinomas per mouse by 76 and ...
Daugherity Erin K - - 2012
Steatoapoptosis is a hallmark of non-alcoholic fatty liver disease (NAFLD) and is an important factor in liver disease progression. We hypothesized that increased reactive oxygen species resulting from excess dietary fat contribute to liver disease by causing DNA damage and apoptotic cell death, and tested this by investigating the effects ...
Henkel Anne S - - 2012
Endoplasmic reticulum (ER) stress has been implicated in the pathogenesis of nonalcoholic steatohepatitis. The ER stress response is activated in the livers of mice fed a methionine- and choline-deficient (MCD) diet, yet the role of ER stress in the pathogenesis of MCD diet-induced steatohepatitis is unknown. Using chemical chaperones on ...
Hager Lauren - - 2012
We recently reported that lecithin:cholesterol acyltransferase (LCAT) knock-out mice, particularly in the LDL receptor knock-out background, are hypersensitive to insulin and resistant to high fat diet-induced insulin resistance (IR) and obesity. We demonstrated that chow-fed Ldlr-/-xLcat+/+ mice have elevated hepatic endoplasmic reticulum (ER) stress, which promotes IR, compared with wild-type ...
Karahan Nermin - - 2012
Background/aims: Intestinal bacteria induce endogenous signals that play a pathogenic role in hepatic insulin resistance and non-alcoholic fatty liver disease. Probiotics could modulate the gut flora and could influence the gut-liver axis. We aimed to investigate the preventive effect of two probiotic mixtures on the methionine choline-deficient diet-induced non-alcoholic steatohepatitis ...
Zeng Yue - - 2012
Background/Aims: Endoplasmic reticulum (ER) stress and hypertriglyceridemia (HTG) have been implicated in acute pancreatitis (AP). Methodology: For cellular model, rat exocrine acinar cells were preincubated with palmitic acid (0.05 or 0.1mmol/L, 3h) and stimulated with a cholecystokinin analog, CCK-8 (100pmol/L, 30min). For animal model, rats fed a high-fat diet to ...
Cui Jue - - 2012
This study investigated whether spleen oxidative stress induced by a high-fat diet (HFD) influences the expression of genes involved in B-cell activation, thus leading to B-cell-related immunosuppression. Male C57BL/6 mice were randomly assigned to one of three groups with eight mice in each group. The control group consumed an ordinary ...
Peng Xi - - 2012
The purpose of this 42-day study was to investigate the effects of low selenium (Se) on histopathological changes of spleen, cell cycle and apoptosis of splenocytes, and oxidative status of the spleen. One hundred twenty 1-day-old avian broilers were randomly divided into two groups of 60 each and were fed ...
Kim Patrick J H - - 2012
Pulmonary fat embolism is widely recognised in forensic pathology. Pulmonary fat embolism requires mobilisation of free fat, entry of free fat into the circulation and lodging of fat globules in fine venous capillaries. This paradigm of fat embolisation has been used to support the evidence of antemortem fat depot disruption ...
Woyengo T A - - 2012
An experiment was conducted to determine the apparent ileal digestibility (AID) of amino acids (AA) in zero-tannin faba beans (ZFB; Vicia faba L.) fed to broiler chicks. In total, 120 broiler chicks were divided into 24 groups of 5 birds that were balanced for BW and fed 1 of 3 ...
Hwang Jung Hwan - - 2012
Although the safety of gold nanoparticle (AuNP) use is of growing concern, most toxicity studies of AuNPs had focused on their chemical characteristics, including their physical dimensions, surface chemistry, and shape. The present study examined the susceptibility of rodents with healthy or damaged livers to AuNP-induced hepatotoxicity. To induce a ...
Tuzun Funda - - 2012
Supraphysiologic amounts of oxygen negatively influences brain maturation and development. The aim of the present study was to evaluate whether maternal ω-3 long-chain polyunsaturated fatty acid (ω-3 FA) supplementation during pregnancy protects the developing brain against hyperoxic injury. Thirty-six rat pups from six different dams were divided into six groups ...
Peake Kyle B - - 2012
Niemann-Pick C (NPC) disease is an inherited, progressive neurodegenerative disorder caused by mutations in the NPC1 or NPC2 gene that result in an accumulation of unesterified cholesterol in late endosomes/lysosomes (LE/L) and impaired export of cholesterol from LE/L to the endoplasmic reticulum (ER). Recent studies demonstrate that administration of cyclodextrin ...
Michihara Seiwa - - 2012
Puerarin, a daidzein-8-C glucoside, is the major isoflavonoid in Kudzu (Pueraria lobata), and is unique in that it contains C-C conjugated glucose at position 8 of the isoflavonoid structure. A puerarin diet at a dose of 5 mg/kg b.w./d to fed ovariectomized mice for 2 mo diminished the urinary deoxypyridinoline, ...
Shanmugam Muthu K - - 2012
Prostate cancer is one of the leading causes of cancer death among men worldwide. In this study, using transgenic adenocarcinoma of mouse prostate (TRAMP) mice, the effect of diet enriched with 1% w/w ursolic acid (UA) was investigated to evaluate the stage specific chemopreventive activity against prostate cancer. We found ...
Chae Min Kyung - - 2012
Pentoxifylline (PTX) anti-TNF properties are known to exert hepatoprotective effects in various liver injury models. The aim of this study was to investigate whether PTX has beneficial roles in the development of methionine- and choline-deficient-(MCD-) diet-induced NAFLD SD rats in vivo and TNF-α-induced Hep3B cells in vitro. SD Rats were ...
Wang Hui-Ting - - 2012
Obesity is an important cardiovascular risk factor. This study tested the effect of obesity reduction on preserving left ventricular ejection fraction (LVEF) and attenuating inflammation, oxidative stress and LV remodeling in obese mice. Eight-week-old C57BL/6 J mice (n=24) were equally divided into control (fed a control diet for 22 weeks), obesity (high-fat ...
Varma Shambhu D - - 2012
Development of cataract is associated with apoptotic death of the lens epithelial cells. The purpose of this investigation was to examine whether this could be explained by enhancement in the expression of certain pro-apoptotic microRNAs (miRs), known to induce apoptosis by hybridizing with target mRNAs, with the consequence of gene ...
Tacchi Luca - - 2012
Aquaculture of piscivorous fish is in continual expansion resulting in a global requirement to reduce the dependence on wild caught fish for generation of fishmeal and fish oil. Plant proteins represent a suitable protein alternative to fish meal and are increasingly being used in fish feed. In this study, we ...
Yang Nian-Wan - - 2012
Destructive host-feeding is common in hymenopteran parasitoids. Such feeding may be restricted to host stages not preferred for oviposition. However, whether this is a fixed strategy or can vary according to resource levels or parasitoid needs is less clear. We tested the trade-off between host feeding and oviposition on two ...
Guo Ying - - 2012
NADH-cytochrome b5 oxidoreductase (Ncb5or) in endoplasmic reticulum (ER) is involved in fatty acid metabolism, and Ncb5or(-/-) mice fed standard chow (SC) are insulin-sensitive but weigh less than wild type (WT) littermates. Ncb5or(-/-) mice develop hyperglycemia at about age 7 weeks due to β-cell dysfunction and loss associated with saturated fatty ...
Nalle C L - - 2011
1. Two experiments were conducted to evaluate the nutritional value of three cultivars (Wallan, Tanjil and Borre) of narrow-leafed lupin (Lupinus angustifolius) for broilers. 2. In Experiment 1, the apparent metabolisable energy (AME) and the apparent ileal amino acid digestibility of the three cultivars were determined. The cultivar effects were ...
Fang Longhou - - 2011
Oxidative modification of LDL is an early pathological event in the development of atherosclerosis. Oxidation events such as malondialdehyde (MDA) formation may produce specific, immunogenic epitopes. Indeed, antibodies to MDA-derived epitopes are widely used in atherosclerosis research and have been demonstrated to enable cardiovascular imaging. In this study, we engineered ...
Arumugam Somasundaram - - 2012
Mulberry is commonly used as silkworm diet and an alternative medicine in Japan and China, has recently reported to contain many antioxidative flavanoid compounds and having the free radical scavenging effects. Antioxidants reduce cardiac oxidative stress and attenuate cardiac dysfunction in animals with pacing-induced congestive heart failure. Hence we investigated ...
Fanson Benjamin G - - 2011
Insect lifespan is often closely linked to diet, and diet manipulations have been central to studies of ageing. Recent research has found that lifespan for some flies is maximised on a very low yeast diet, but once all yeast is removed, lifespan drops precipitously. Although effects of yeast availability on ...
Stults-Kolehmainen Matthew A - - 2012
The aim of this study was to determine whether quantity of fat is different across the central (i.e., android, trunk) and peripheral (i.e., arm, leg, and gynoid) regions among young African-American (AA), Asian (AS), Hispanic (HI), and non-Hispanic white (NHW) women. A cohort of 1,161 women (18-30 years) from university ...
Almeida F N - - 2011
The objectives of this experiment were to determine the apparent ileal digestibility (AID) and the standardized ileal digestibility (SID) of CP and AA in bakery meal, corn gluten meal, corn gluten feed, corn germ meal, and hominy feed and to compare these values to the AID and SID of CP ...
Kong C - - 2011
The regression method was used in a 14-d broiler chicken study to determine the true ileal digestibility of amino acid (AA) and protein utilization in canola meal (CM, 388 g of CP/kg) without or with added phytase. Experimental treatments consisted of 2 factors, phytase at 2 levels (0 or 1,500 ...
Roberts J - - 2011
The diets of Antarctic toothfish Dissostichus mawsoni and Patagonian toothfish Dissostichus eleginoides were examined around the South Sandwich Islands in the Southern Ocean, one of few regions with overlapping populations of the two species. Despite large differences in the proportion of stomachs containing prey (76·2% of D. mawsoni compared to ...
Rothman Jessica M - - 2011
It is widely assumed that terrestrial food webs are built on a nitrogen-limited base and consequently herbivores must compensate through selection of high-protein foods and efficient nitrogen retention. Like many folivorous primates, gorillas' diet selection supports this assumption, as they apparently prefer protein-rich foods. Our study of mountain gorillas (Gorilla ...
Ilmonen Johanna - - 2011
To establish whether probiotic supplemented dietary counselling influences maternal anthropometric measurements during and after pregnancy. At the first trimester of pregnancy 256 women were randomly assigned to receive nutrition counselling to modify dietary intake according to current recommendations or as controls; dietary intervention groups were further randomized to receive probiotics ...
Martínez Sonia - - 2011
Martínez, S, Pasquarelli, BN, Romaguera, D, Arasa, C, Tauler, P, and Aguiló, A. Anthropometric characteristics and nutritional profile of young amateur swimmers. J Strength Cond Res 25(4): 1126-1133, 2011-The aim of this study was to evaluate nutritional and anthropometric profiles of young swimmers belonging to semiprofessional teams. Thirty-six caucasian adolescent ...
Bechara F G - - 2012
Background  Injections with phosphatidylcholine- and deoxycholate-containing substances are used to treat localized fat accumulation and lipomas. It is believed that the injected substances induce fat cell destruction with subsequent acute panniculitis followed by a repair process of the treated fat tissue. Objectives  We investigated whether necrosis or apoptosis of fat ...
Jacka Felice N - - 2011
Recent epidemiological evidence has indicated a role for diet quality in unipolar depressive illness. This study examined the association between diet quality and bipolar disorder (BD) in an epidemiological cohort of randomly selected, population-based women aged 20-93years. An a priori diet quality score was derived from food frequency questionnaire data, ...
Marion C - - 2011
The feeding habits of the shortnose guitarfish, Zapteryx brevirostris, were studied based on 382 specimens from the northern São Paulo coast, southeast Brazil. The diet showed a predominance of crustaceans (carideans and amphipods), polychaete annelids, and occasionally small fish, sipunculids, and cephalopods. The diets of males and females were similar; ...
Sakurai Masaru M Department of Epidemiology and Public Health, Kanazawa Medical University, Ishikawa, - - 2011
A direct relationship of dietary cholesterol to blood pressure of men has been reported in a few observational studies from the USA. It is not clear whether this association prevails consistently, for example, in populations with varied dietary habits, across ethnic groups, and sexes. Cross-sectional data from the International Study ...
De Ceglie A - - 2011
Identification of modifiable risk factors is an attractive approach to primary prevention of esophageal adenocarcinoma (EAC) and esophagogastric junction adenocarcinoma (EGJAC). We conducted a review of the literature to investigate the association between specific dietary components and the risk of Barrett’s esophagus (BE), EAC and EGJAC, supposing diet might be ...
1 2 3 4 5 6 7 8 9 10 >