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Nahak Prasant P Department of Chemistry, University of North - - 2014
Lung surfactant is a complex mixture of lipid and protein, responsible for alveolar stability, becomes dysfunctional due to alteration of its structure and function by leaked serum materials in disease. Serum proteins, cholesterol and low density lipoprotein (LDL) were studied with bovine lipid extract surfactant (BLES) using Langmuir films, and ...
Ahmadipour Behnam B Department of Animal Science, Shahrekord University, Shahrekord 88186-34141, Iran. Electronic address: - - 2014
Kelussia odoratissima Mozzaf, formerly Apium odoratissima, is a plant locally called "Kelussia odoratissima Mozzaf", found in central Zagros region of Iran. Leaves and stems of the plant are traditionally used in the treatment of hypertension and inflammation. Lowering blood pressure effects of Kelussia odoratissima Mozzaf (wild celery) was evaluated in ...
Fujiwara Mayu M Division of Nutrition and Metabolism, Kobe University Graduate School of Health Sciences, Kobe, - - 2014
Acute lung injury (ALI) is less severe in obese than in nonobese patients, but the mechanism is unclear. Secretory leukocyte protease inhibitor (SLPI) is the key anti-inflammatory protein in various lung diseases. We have previously reported changes of the surgical stress in obese rats using lard-based high-fat diet (HFD). The ...
Takata Kohei K Department of Cardiology, Fukuoka University School of - - 2014
Background:Smoking cessation reduces the risk of cardiovascular disease (CVD) and improves clinical outcomes in public health. We studied the effect of smoking cessation on high-density lipoprotein (HDL) functionality.Methods and Results:We randomly treated 32 smokers with varenicline or a transdermal nicotine patch as part of a 12-week smoking cessation program (The VN-SEESAW Study). ...
Nogradi N N Department of Veterinary Clinical Sciences, Purdue University, West Lafayette, - - 2014
Omega-3 polyunsaturated fatty acid (PUFA) may benefit humans and animals with chronic inflammatory diseases. Omega-3 PUFA supplementation improves clinical signs, lung function, and airway inflammation in horses with recurrent airway obstruction (RAO) and inflammatory airway disease (IAD). Eight research horses and 35 client-owned horses. A pilot study examined the dose ...
Cho Yoonsu Y Department of Food and Nutrition, Korea University, Seoul 136-703, Republic of Korea; Department of Public Health Sciences, Graduate School, Korea University, Seoul 136-703, Republic of - - 2014
In the present study, we evaluated the association between dietary patterns and pulmonary functions in Korean women older than 40 years. This study analyzed the data from the Korea National Health and Nutrition Examination Survey IV and V (2007-2010). In total, 7,615 women were included in the analysis. Using principal ...
Liu Peng-Yan PY College of Chemistry and Environmental Science, Hebei University, Baoding, Hebei, - - 2014
To reveal what degree bioaccumulation of polybrominated diphenyl ethers (PBDEs) depends on exposure time and other factors, we conducted a semi-field experiment for a year (June 2008-June 2009) in a village in an e-waste recycling site in Taizhou, China. Approximately one hundred of juvenile ducks (Anas domestica Linnaeus) were entrusted ...
Yu Xiaohong X Medical College of Soochow University, Suzhou 215123, - - 2014
The evaluation of toxicological effects of nanoparticulate matter is increasingly important due to their growing occupational use and presence as compounds in consumer products. Numerous studies have shown that exposure to nanosized particles lead to systemic inflammation in experimental animals, but whether long-term exposure to nanosized particles induces atherogenesis is ...
Kishikawa Nobusuke N Department of General Internal Medicine, Hiroshima University Hospital, 1-2-3, Kasumi, Minami-ku, Hiroshima, 734-8551, - - 2014
Ezetimibe inhibits cholesterolabsorption by blocking Niemann-Pick C1 like 1 proteins (NPC1L1) expressed in small intestine. Since NPC1L1 is also expressed in human liver, ezetimibe conceivably alters biliary lipid compositions. Here, we performed a clinical trialinvestigating the effect of ezetimibe on biliary lipidsusing transnasal-endoscopy for bile collection. Eight patients with dyslipidemia ...
Zechner Rudolf R Institute of Molecular Biosciences, University of Graz, 8010 Graz, Austria. Electronic address: - - 2014
The breakdown of cellular fat stores fuels energy production and multiple anabolic processes. Albert et al. (2014) demonstrate that the lack of hormone-sensitive lipase, a member of the enzyme trio that catabolizes fat, has pronounced effects on lipid metabolism, glucose homeostasis, and cell signaling in humans.
Grolmusová Zuzana Z Comenius University in Bratislava, Faculty of Mathematics, Physics and Informatics, Department of Experimental Physics, Mlynská dolina F2, 842 48 Bratislava, Slovakia; State Geological Institute of Dionýz Štúr, Laboratory of Isotope Geology, Mlynská dolina 1, 817 04 Bratislava, Slovakia. Electronic address: - - 2014
Stable isotope composition of human fingernails has proven to be useful for documenting human dietary information and geographical patterns in archeological, forensic, anthropological and biological studies. Therefore, it is of interest to detect all factors influencing the stable isotopic composition in the certain regions in the world. Carbon and nitrogen ...
Kuzaj Patricia - - 2014
Dysregulations in cholesterol and lipid metabolism have been linked to human diseases like hypercholesterolemia, atherosclerosis or the metabolic syndrome. Many ABC transporters are involved in trafficking of metabolites derived from these pathways. Pseudoxanthoma elasticum (PXE), an autosomal-recessive disease caused by ABCC6 mutations, is characterized by atherogenesis and soft tissue calcification. ...
Rosenbaum Michael M M Rosenbaum, Division of Molecular Genetics, Columbia University College of Physicians & Surgeons, New York, United States - - 2014
The hyperphagia, low sympathetic nervous system tone, and decreased circulating concentrations of bioactive thyroid hormones that are common to states of congenital leptin deficiency and hypoleptinemia following and during weight loss suggest that the major physiological function of leptin is to signal states of negative energy balance and decreased energy ...
Solinas Paola P Department of Biomedical Sciences, University of Cagliari, Cittadella Universitaria di Monserrato, Cagliari, - - 2014
Non-alcoholic fatty liver disease (NAFLD) is a clinical-pathological syndrome that includes a wide spectrum of morphological alterations. In research, animal models are crucial in evaluating not only the pathogenesis of NAFLD and its progression, but also the therapeutic effects of various agents. Investigations on the ultrastructural features of NAFLD in ...
Prasad Anil R AR Anil R Prasad, Department of Pathology, Northwest Medical Center, Tucson, AZ 85741, United - - 2014
To investigate the close parallels between our novel diet-related mouse model of colon cancer and human colon cancer. Twenty-two wild-type female mice (ages 6-8 wk) were fed the standard control diet (AIN-93G) and an additional 22 female mice (ages 6-8 wk) were fed the control diet supplemented with 0.2% deoxycholic ...
Dey Ramendra Sundar RS Department of Chemistry, Indian Institute of Technology, Kharagpur 721302, - - 2014
A new approach for the one-pot synthesis of reduced graphene oxide-dendritic Pd nanoparticle (rGO-nPd) hybrid material and the development of biosensing scaffold for the amperometric sensing of H2O2 and total cholesterol in human serum are described. In situ reduction of both graphene oxide (GO) and PdCl4(2-) in acidic solution was ...
Ma A Zhi - - 2014
The nuclear receptor liver X receptor (LXR) has two isoforms: LXRalpha and LXRbeta. LXR activation promotes cholesterol efflux in macrophages, but the relative importance of each LXR isoform in mediating cholesterol efflux remains elusive. We evaluated the ability of different doses of LXRs agonist T0901317 to affect cholesterol efflux in ...
Menéndez Lumila L CONICET, División Antropología, Museo de La Plata (UNLP), Paseo del Bosque S/N, La Plata, 1900, Buenos Aires, - - 2014
Ecological factors can be important to shape the patterns of morphological variation among human populations. Particularly, diet plays a fundamental role in craniofacial variation due to both the effect of the nutritional status-mostly dependent on the type and amount of nutrients consumed-on skeletal growth and the localized effects of masticatory ...
Fernández-García Elisabet E Institute of Biochemistry and Molecular Biology I, Faculty of Medicine, Heinrich-Heine-University Düsseldorf, PO Box 101007, D-40001 Düsseldorf, Germany. - - 2014
There is considerable interest in the concept of additional endogenous photoprotection by dietary antioxidants. A number of efficient micronutrients are capable of contributing to the prevention of UV damage in humans. These compounds protect molecular targets by scavenging reactive oxygen species, including excited singlet oxygen and triplet state molecules, and ...
Myles Ian A - - 2014
While numerous changes in human lifestyle constitute modern life, our diet has been gaining attention as a potential contributor to the increase in immune-mediated diseases. The Western diet is characterized by an over consumption and reduced variety of refined sugars, salt, and saturated fat. Herein our objective is to detail ...
Cooper Jamie A JA Department of Nutritional Sciences,Texas Tech - - 2014
As obesity continues to be a global epidemic, research into the mechanisms of hunger and satiety and how those signals act to regulate energy homeostasis persists. Peptide YY (PYY) is an acute satiety signal released upon nutrient ingestion and has been shown to decrease food intake when administered exogenously. More ...
Hur Sun Jin SJ Department of Animal Science and Technology, Chung-Ang University, 4726 Seodong-daero, Daedeok-myeon, Anseong-si, Gyeonggi-do 456-756, Republic of - - 2015
In this study, beef patties were encapsulated with 3% chitosan, pectin, onion powder, or green tea powder and the beef patties were then passed through an in vitro human digestion model. The total lipid digestibility was lowest (p<0.05) in beef patties encapsulated with chitosan and pectin after digestion in the ...
Seiquer Isabel I Departamento de Fisiología y Bioquímica de la Nutrición Animal (INAN), Estación Experimental del Zaidín (CSIC), Armilla, Granada, - - 2014
Scarce data are available concerning effects of certain bioactive substances such as Maillard reaction products (MRP) on the gut microbiota composition, and the question of how a diet rich in MRP affects gut microbiota in humans is still open. Two experiments were conducted. In expt. 1, adolescents consumed diets either ...
Taylor Janice M W - - 2014
The aim of this study was to establish mitochondrial cholesterol trafficking 18kDa translocator protein (TSPO) as a potential therapeutic target, capable of increasing macrophage cholesterol efflux to (apo)lipoprotein acceptors. Expression and activity of TSPO in human (THP-1) macrophages were manipulated genetically, and by the use of selective TSPO ligands. Cellular ...
Thomaz Débora M C DM Universidade Federal de Mato Grosso do Sul (UFMS), Campo Grande, MS, - - 2014
to evaluate phenylalanine plasma profile in preterm newborns fed different human milk diets. twenty-fourvery-low weight preterm newbornswere distributed randomly in three groups with different feeding types: Group I: banked human milk plus 5% commercial fortifier with bovine protein, Group II: banked human milk plus evaporated fortifier derived from modified human ...
Forshaw R R Honorary Research Associate, KNH Centre for Biomedical Egyptology, Faculty of Life Sciences, The University of Manchester/Dental - - 2014
What can the study of ancient teeth tell us about the dietary habits of our ancestors? Diet plays a prominent role in the organisation and evolution of human cultures and an increasingly diverse array of analytical techniques are available to help reconstruct diet in ancient populations. Dental palaeopathology is particularly ...
Hullar Meredith A J MA From the *Public Health Sciences Division, Fred Hutchinson Cancer Research Center, Seattle, WA, and †Department of Epidemiology, School of Public Health, University of Washington, Seattle, - - 2014
Increasingly, the gut microbiome is implicated in the etiology of cancer, not only as an infectious agent but also by altering exposure to dietary compounds that influence disease risk. Whereas the composition and metabolism of the gut microbiome is influenced by diet, the gut microbiome can also modify dietary exposures ...
Chen Miaoxin M Department of Obstetrics and Gynaecology, The Affiliated Hospital of Guiyang Medical College, Guiyang, China, - - 2014
In-vitro fertilization (IVF) may influence the metabolic health of children. However, in humans, it is difficult to separate out the relative contributions of genetics, environment, or the process of IVF, which includes ovarian stimulation and embryo culture. Therefore, we examined glucose metabolism in young adult humans and in adult male ...
Spruiell Krisstonia K Cardiovascular & Metabolic Diseases Research Program, Julius L. Chambers Biomedical/Biotechnology Research Institute, North Carolina Central University, 700 George St., Durham, NC 27707, USA; Department of Biology, North Carolina Central University, Durham, NC 27707, - - 2014
Obesity is a complex metabolic disorder that is more prevalent among women. Until now, the only relevant rodent models of diet-induced obesity were via the use of ovariectomized ("postmenopausal") females. However, recent reports suggest that the xenobiotic nuclear receptor pregnane X receptor (PXR) may contribute to obesity. Therefore, we compared ...
D'Alessandro Angela Gabriella - - 2014
Background: Oxidative damage of tissues and cellular components is a primary or secondary cause of many human diseases and is associated with the welfare and productivity of farm animals. Natural antioxidants have gained attention for the prevention of oxidative damage-related diseases. Aim of the Study: To determine the effects of ...
Thorn Stephanie R SR Department of Pediatrics, University of Colorado Anschutz Medical Campus, Aurora, Colorado, - - 2014
The origins of non-alcoholic fatty liver disease (NAFLD) may lie in early intrauterine exposures. Here we examined the maternal response to chronic maternal high fat (HF) diet, and the impact of post-weaning healthy diet on mechanisms for NAFLD development in juvenile non-human primate (NHP) offspring at 1 yr of age. ...
Pikuleva Irina A IA Department of Ophthalmology and Visual Sciences, Case Western Reserve University, Cleveland, Ohio 44106, United States. Electronic address: - - 2014
Historically understudied, cholesterol in the retina is receiving more attention now because of genetic studies showing that several cholesterol-related genes are risk factors for age-related macular degeneration (AMD) and because eye pathology studies showing high cholesterol content of drusen, aging Bruch's membrane, and newly found subretinal lesions. The challenge before ...
Otles Semih S Department of Food Engineering, Engineering Faculty, Ege University of Izmir, - - 2014
Dietary fi bre is a group of food components which is resistant to digestive enzymes and found mainly in cereals, fruits and vegetables. Dietary fi ber and whole grains contain a unique blend of bioactive components including resistant starches, vitamins, minerals, phytochemicals and antioxidants. Dietary fi ber which indigestible in ...
Abranches Andrea D AD Instituto Nacional de Saúde da Mulher, Criança e Adolescente Fernandes Figueira (Fiocruz), Rio de Janeiro, RJ, - - 2014
to analyze the changes in human milk macronutrients: fat, protein, and lactose in natural human milk (raw), frozen and thawed, after administration simulation by gavage and continuous infusion. an experimental study was performed with 34 human milk samples. The infrared spectrophotometry using the infrared analysis equipment MilkoScan Minor® (Foss, Denmark) ...
Mutalik Srinivas S Department of Pharmaceutics, Manipal College of Pharmaceutical Sciences - - 2014
Abstract Cryopreservation of spermatozoa plays a significant role in reproductive medicine and fertility preservation. Chicken egg yolk is used as an extender in cryopreservation of human spermatozoa using glycerol egg yolk citrate (GEYC) buffered medium. Even though 50% survival of spermatozoa is generally achieved with this method, the risk of ...
Shao Baohai B Department of Medicine, University of - - 2014
The efflux capacity of HDL with cultured macrophages associates strongly and negatively with CAD status, indicating that impaired sterol efflux capacity might be a marker-and perhaps mediator-of atherosclerotic burden. However, the mechanisms that contribute to impaired sterol efflux capacity remain poorly understood. To determine the relationship between myeloperoxidase-mediated oxidative damage ...
Raubenheimer David D Charles Perkins Centre and Faculty of Veterinary Science and School of Biological Sciences, University of Sydney, Sydney, Australia. Electronic address: - - 2014
We present a geometric model for examining the macronutrient contributions of insects in the diets of pre-agricultural humans, and relate the findings to some contemporary societies that regularly eat insects. The model integrates published data on the macronutrient composition of insects and other foods in the diets of humans, recommended ...
Chen Jia J School of Chemical Engineering & Technology, Tianjin Univ, Tianjin, 300072, - - 2014
The 100 trillion microbes in human gut coevolve with the host and exert significant influences on human health. The gut microbial composition presents dynamic changes correlated with various factors including host genotypes, age, and external environment. Effective manipulation of the gut microbiota through diets (both long-term and short-term diet patterns), ...
El Khoury Petra P INSERM-UPMC UMR1166, Hôpital de la Pitié, Paris, France; Laboratoire de Biochimie, Faculté de Pharmacie et Pôle Technologie Santé, Université Saint-Joseph, Beirut, - - 2014
CETP or HL deficiencies lead to a marked increase in HDL-C levels however the atheroprotective effect of this phenotype, in particular the ability of HDL particles to remove cholesterol from human macrophages, remains to be determined. We measured cholesterol efflux from human THP-1 macrophages to total plasma or to isolated ...
Dipatrizio Nicholas V NV Department of Anatomy and Neurobiology, University of California, Irvine, School of Medicine. Electronic address: - - 2014
Mounting evidence suggests that gustation is important for the orosensory detection of dietary fats, and might contribute to preferences that humans, rodents, and possibly other mammals exhibit for fat-rich foods. In contrast to sweet, sour, salty, bitter, and umami, fat is not widely recognized as a primary taste quality. Recent ...
Guo Lei L Environmental Toxicology Graduate Program, University of California, Riverside, CA 92521-0403, United - - 2014
Human exposure to arsenic in drinking water is a widespread public health concern, and such exposure is known to be associated with many human diseases. The detailed molecular mechanisms about how arsenic species contribute to the adverse human health effects, however, remain incompletely understood. Monomethylarsonous acid [MMA(III)] is a highly ...
Leonard William R WR Department of Anthropology, Northwestern University, 1810 Hinman Avenue, Evanston, IL 60208. Electronic address: - - 2014
This paper draws on comparative data to explore the evolutionary origins of human nutritional needs and the diverse strategies used by human populations to meet those needs. Humans have evolved distinctive nutritional characteristics associated the high metabolic costs of our large brains. The evolution of larger hominid brain size necessitated ...
Munukka Eveliina E Department of Health Sciences, University of Jyväskylä, P.O.Box 35, 40014 University of Jyväskylä, Finland; Department of Medical Microbiology and Immunology, University of Turku, - - 2014
Recent evidence suggests that in animals gut microbiota composition (GMC) affects the onset and progression of hepatic fat accumulation. The aim of this study was to investigate in humans whether subjects with high hepatic fat content (HHFC) differ in their GMC from those with low hepatic fat content (LHFC), and ...
Degen Julia - - 2014
3-Deoxyglucosone (3-DG), a reactive 1,2-dicarbonyl compound derived from D-glucose in food and in vivo, is an important precursor for advanced glycation endproducts (AGEs) At present, virtually no information about the metabolic transit of dietary 3-deoxyglucosone is available. One possible metabolic pathways of 3-DG during digestion is enzymatic transformation to less ...
Lammel Lindemann Jan A JA Houston Methodist Research Institute, Houston, Texas; Escuela de Biotecnología y Alimentos, Instituto Tecnológico y de Estudios Superiores de Monterrey, - - 2014
Thyroid hormone (TH) modulates serum cholesterol by acting on TH receptor β1 (TRβ1) in liver to regulate metabolic gene sets. In rodents, one important TH regulated step involves induction of Cyp7a1, an enzyme in the cytochrome P450 family, which enhances cholesterol to bile acid conversion and plays a crucial role ...
McGrew William C WC Division of Biological Anthropology, Department of Archaeology & Anthropology, University of Cambridge, Fitzwilliam St., Cambridge CB21QH, UK. Electronic address: - - 2014
The role of invertebrates in the evolution of human diet has been under-studied by comparison with vertebrates and plants. This persists despite substantial knowledge of the importance of the 'other faunivory', especially insect-eating, in the daily lives of non-human primates and traditional human societies, especially hunters and gatherers. Most primates ...
Rosqvist Fredrik F Clinical Nutrition and Metabolism, Department of Public Health and Caring Sciences, Uppsala University, - - 2014
Excess ectopic fat storage is linked to type 2 diabetes. The importance of dietary fat composition for ectopic fat storage in humans is unknown. We investigated liver fat accumulation and body composition during overfeeding saturated (SFA) or polyunsaturated (PUFA) fat. LIPOGAIN was a double-blind, parallel-group, randomized trial. Thirty-nine young and ...
Walewski José L JL Dept of Medicine, Columbia University Medical Center, New York, NY, - - 2014
Objective: Microarray studies identified Ch12:orf39 (Spexin) as the most dysregulated gene in obese human fat. Therefore we examined its role in obesity pathogenesis. Design and Methods: Spexin effects on food intake, meal patterns, body weight, Respiratory Exchange Ratio (RER), and locomotor activity were monitored electronically in C57BL/6J mice or Wistar ...
Van Loo-Bouwman Carolien A CA Department of Gastroenterology and Hepatology, Radboud University Nijmegen Medical Centre, Geert Grooteplein 8, 6525 GA Nijmegen, The - - 2014
Vitamin A equivalency of β-carotene (VEB) is defined as the amount of ingested β-carotene in μg that is absorbed and converted into 1 μg retinol (vitamin A) in the human body. The objective of the present review was to discuss the different estimates for VEB in various types of dietary food ...
Tuohy Kieran M KM Nutrition and Nutrigenomics Group, Department of Food Quality and Nutrition, Research and Innovation Centre, Fondazione Edmund Mach, San Michele all'Adige, Trento 38010, - - 2014
The human gut microbiota has been identified as a possible novel CVD risk factor. This review aims to summarise recent insights connecting human gut microbiome activities with CVD and how such activities may be modulated by diet. Aberrant gut microbiota profiles have been associated with obesity, type 1 and type ...
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