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Vicente Gabriela Câmara GC Federal Fluminense University (UFF), Laboratory of Experimental Nutrition (LabNE), College of Nutrition, Niterói-RJ, - - 2014
Diabetes during pregnancy is associated with cardiovascular complications in the fetus and extends into adulthood. Therapeutic applications of flaxseed has been studied in cardiovascular disorders, because it oilseed the best plant source of omega-3 fatty acid, which are currently considered by researchers, essential protective against cardiovascular disease. The aim of ...
Duthie Susan J SJ School of Pharmacy and Life Sciences, Robert Gordon University, Aberdeen, UK, - - 2015
Low B vitamin status is linked with human vascular disease. We employed a proteomic and biochemical approach to determine whether nutritional folate deficiency and/or hyperhomocysteinemia altered metabolic processes linked with atherosclerosis in ApoE null mice. Animals were fed either a control fat (C; 4 % w/w lard) or a high-fat [HF; ...
Castro-Perez Jose J Merck & Co., Inc, Merck Research Laboratories, Kenilworth, NJ, 07033, - - 2014
The ability to quantify rates of formation, regression and/or remodeling of atherosclerotic plaque should facilitate a better understanding of the pathogenesis and management of cardiovascular disease. In the current study, we coupled a stable isotope labeled tracer protocol with matrix-assisted laser desorption/ionization mass spectrometry imaging (MALDI-MSI) to examine spatial and ...
Thompson Jennifer A JA Department of Physiology and Pharmacology, The University of Western London, Ontario, Canada Department of Obstetrics and Gynaecology, The University of Western London, Ontario, Canada - - 2014
The association between intrauterine growth restriction (IUGR) and hypertension is well- established, yet the interaction between IUGR and other pathogenic contributors remains ill-defined. This study examined the independent and interactive effects of fetal growth reduction resulting in low birth weight (LBW), and postnatal western diet (WD) on vascular function. Growth ...
Li Gang - - 2014
Gamma-glutamyl transpeptidase (GGT) is now considered to be one of the risk factors for cardiovascular disease. However, whether statins can alter GGT levels in arterial atheromatous plaque has not yet been studied. Therefore, the aim of this study is to determine whether statins can effectively decrease the expression of GGT ...
Agbor Larry N LN Department of Pharmaceutical Sciences, University of New Mexico, Albuquerque, New Mexico (L.N.A., E.F.W., M.K.W.); Lipidomix GmbH, Berlin, Germany (M.R.); and Max-Delbrück Center for Molecular Medicine, Berlin, Germany - - 2014
The mechanisms that mediate the cardiovascular protective effects of omega 3 (n-3) polyunsaturated fatty acids (PUFAs) have not been fully elucidated. Cytochrome P450 1A1 efficiently metabolizes n-3 PUFAs to potent vasodilators. Thus, we hypothesized that dietary n-3 PUFAs increase nitric oxide (NO)-dependent blood pressure regulation and vasodilation in a CYP1A1-dependent ...
Shing Cecilia M CM School of Health Sciences, University of Tasmania, Launceston, - - 2014
Inflammation and endothelial dysfunction contribute to cardiovascular disease, prevalent in CKD. Antioxidant supplements such as tocopherols may reduce inflammation and atherosclerosis. This study aimed to investigate the effect of tocopherol supplementation on vascular function, aortic plaque formation and inflammation in apolipoprotein E-/- mice with 5/6 nephrectomy as a model of ...
Dhahri Wahiba - - 2014
The composition of a diet can influence myocardial metabolism and development of left ventricular hypertrophy (LVH). The impact of a high-fat diet in chronic left ventricular volume overload (VO) causing eccentric LVH is unknown. This study examined the effects of chronic ingestion of a high-fat diet in rats with chronic ...
Um Min Young MY Metabolism and Nutrition Research Group, Korea Food Research Institute, Seongnam, South - - 2014
Curcumin, the yellow substance found in turmeric, possesses antioxidant, anti-inflammation, anticancer, and lipid-lowering properties. Because we hypothesized that curcumin could ameliorate the development of atherosclerosis, the present study focused on the effects and potential mechanisms of curcumin consumption on high-cholesterol diet-induced atherosclerosis in rabbits. During our study, New Zealand white ...
Fernández-Murga María Leonor ML From the 1Fundación para el Fomento de la Investigación Sanitaria y Biomédica de la Comunitat Valenciana, Valencia, Spain; 2Vascular Biology Unit, Department of Molecular and Cellular Pathology and Therapy, Instituto de Biomedicina de Valencia, Valencia, Spain; 3Service of Orthopedic Surgery, Complexo Hospitalario Universitario de Santiago de Compostela, A Coruña, Spain; 4Trabeculae SL, San Cibrao das Viñas, Ourense, Spain; 5Department of Functional Biology and Physical Anthropology, Faculty of Biological Sciences, University of Valencia, Valencia, Spain; 6Laboratory of Molecular and Genetic Cardiovascular Pathophysiology, Department of Epidemiology, Atherothrombosis, and Imaging, Centro Nacional de Investigaciones Cardiovasculares, Madrid, Spain; 7Department of Pediatrics, Obstetrics, and Gynecology, University of Valencia, Valencia, Spain; and 8Service of Obstetrics and Gynecology, Hospital Universitario Dr. Peset, Valencia, - - 2014
The common inflammatory pathophysiology has nourished the hypothesis of a relationship between osteoporosis and cardiovascular disease. Estrogens are key agents in the modulation of both processes. We investigated whether induction of atherosclerosis affects bone and whether estrogens modulate both processes. Female apolipoprotein E-deficient mice (a well-established model of atherogenesis) were ...
Shah Amy S AS Department of Pediatrics, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, - - 2014
Dyslipidemia contributes to the increased risk of cardiovascular disease in persons with type 1 diabetes (T1D). Weight control is commonly recommended as a treatment for dyslipidemia. However, the extent to which decreases in weight affect the lipid profile in youth with T1D is not known. Therefore, we tested the hypothesis ...
Forsberg C W CW Departments of Molecular and Cellular Biology - - 2014
A transgenic line of Yorkshire pigs named the Cassie ( CA: ) line was produced with a low copy number phytase transgene inserted in the genome. The transgenic line efficiently digests P, Ca and other major minerals of plant dietary origin. The objectives of this study were to i) compare ...
Shigematsu Erina E Department of Endocrinology and Diabetes, Yokohama City University Medical Center, Yokohama, - - 2014
Animal studies have demonstrated that an inhibition of DPP-4 has an impact on the secretion of cholesterol and apoB by the small intestine. However, there is no consensus about the changes of the lipid profile following administration of sitagliptin. Accordingly, we treated patients who had type 2 diabetes complicated by ...
Saadane Aicha A Department of Ophthalmology and Visual Sciences, Cleveland Clinic Lerner College of Medicine, Case Western Reserve University, Cleveland, - - 2014
Cholesterol elimination from nonhepatic cells involves metabolism to side-chain oxysterols, which serve as transport forms of cholesterol and bioactive molecules modulating a variety of cellular processes. Cholesterol metabolism is tissue specific, and its significance has not yet been established for the retina, where cytochrome P450 enzymes (CYP27A1 and CYP46A1) are ...
Rutten Geert M - - 2014
BackgroundCombined lifestyle interventions (CLIs) have been advocated as an effective instrument in efforts to reduce overweight and obesity. The odds of maintaining higher levels of physical activity (PA) and healthier dietary behaviour improve when people are more intrinsically motivated to change their behaviour. To promote the shift towards more autonomous ...
Portnichenko Hv H Bogomoletz Institute of Physiology, Department of General and Molecular Patophysiology, Kiev, - - 2014
Investigate pathophysiological changes in cardiovascular system and discover the role of SREBP related system in this process under conditions of essential hypertension and high cholesterol diet in rats. 6 month old male Wistar rats and spontaneously hypertensive rats (SHR) were taken as the objects of research. They were fed with ...
Wei Jiankai J Key Laboratory of Experimental Marine Biology, Institute of Oceanology, Chinese Academy of Sciences, Qingdao 266071, China; University of Chinese Academy of Sciences, Beijing 100049, - - 2014
The Pacific white shrimp (Litopenaeus vannamei), with high commercial value, has a typical metamorphosis pattern by going through embryo, nauplius, zoea, mysis and postlarvae during early development. Its diets change continually in this period, and a high mortality of larvae also occurs in this period. Since there is a close ...
Catenacci Victoria A VA Division of Endocrinology, Metabolism, and Diabetes, Department of Medicine, Anschutz Health and Wellness Center, University of Colorado Anschutz Medical Campus, Aurora, Colorado, - - 2014
The aim of this cross-sectional study was to evaluate prevalence of and strategies behind low/no calorie sweetened beverage (LNCSB) consumption in successful weight loss maintainers. An online survey was administered to 434 members of the National Weight Control Registry (NWCR, individuals who have lost ≥13.6 kg and maintained weight loss ...
Hazim Jana - - 2014
Epidemiological studies have found a U-shaped relationship between serum phosphorus and cardiovascular disease (CVD). The mechanism(s) behind such a relationship are poorly understood. Phosphorus (P) is reported to improve insulin sensitivity, which is involved in lipid metabolism, and thus we were interested in determining the impact of phosphorus ingestion on ...
Leung Amy A City of Hope, United - - 2014
Metabolic diseases result from multiple genetic and environmental factors. We report here that one manner in which environmental factors can contribute to metabolic disease progression is through modification to chromatin. We demonstrate that high fat (HF) diet leads to chromatin remodeling in the livers of C57BL/6J mice, as compared to ...
Seamster Virginia A VA a Department of Environmental Sciences ; University of Virginia ; Charlottesville , VA , - - 2014
Drylands typically have strong seasonal variation in rainfall and primary productivity. This study examines the effects of seasonal change in grass-derived resource availability on the base of the food chain of a mammalian predator. Seasonal changes in live grass cover were measured in two vegetation types at the Sevilleta National ...
Richard Caroline C Institute of Nutrition and Functional Foods, Laval University, Quebec City, Que., - - 2014
Background/Aims: The objective of this preliminary study was to examine the impact of the Mediterranean diet (MedDiet) on the high-density lipoprotein (HDL) proteome in men with the metabolic syndrome (MetS). Methods: Twenty-six men with the MetS first consumed a standardized baseline North American isoenergetic control diet (5 weeks) and then ...
Bernardi Stella S Department of Morphology, Surgery and Experimental Medicine and LLTA Centre, University of Ferrara, Via Fossato di Mortara 66, 44100 Ferrara, Italy; Baker IDI, Heart & Diabetes Research Institute, 75 Commercial Road, VIC 3004 Melbourne, Australia. Electronic address: - - 2014
Inflammation is believed to link obesity to insulin resistance, as in the setting of metabolic syndrome (MetS). Osteoprotegerin (OPG) is a soluble protein that seems to exert proatherogenic and prodiabetogenic effects. This study aims at determining OPG levels in MetS and whether OPG might contribute to MetS development and progression. ...
Humphrey Louise T LT The Natural History Museum, Earth Sciences , London , - - 2014
Abstract Context: Nursing behaviour has significant implications for individual health and population dynamics. Reconstruction of infant and early childhood diet has become a key focus in studies of past populations. Objective: This paper reviews knowledge about how trace element and stable isotope composition of bone and dental tissues changes during ...
Katta Rajani R Baylor College of Medicine, Houston, - - 2014
For decades, it was thought that many common dermatological conditions had no relationship to diet. Studies from recent years, however, have made it clear that diet may influence outcome. In this review, the authors focus on conditions for which the role of diet has traditionally been an underappreciated aspect of ...
Johnston Jessica L JL Office of the UN Special Envoy for Financing of the Health Millennium Development Goals and Malaria, MDG Health Alliance, New York, NY - - 2014
The confluence of population, economic development, and environmental pressures resulting from increased globalization and industrialization reveal an increasingly resource-constrained world in which predictions point to the need to do more with less and in a "better" way. The concept of sustainable diets presents an opportunity to successfully advance commitments to ...
Jahagirdar Ravi R Resverlogix Corp., Calgary, Canada. Electronic address: - - 2014
Despite the benefit of statins in reducing cardiovascular risk, a sizable proportion of patients still remain at risk. Since HDL reduces CVD risk through a process that involves formation of pre-beta particles that facilitates the removal of cholesterol from the lipid-laden macrophages in the arteries, inducing pre-beta particles, may reduce ...
Goncalves N N University of Porto, Faculty of Medicine, Department of Physiology and Cardiothoracic Surgery, Porto, - - 2014
Two major cardiovascular risk factors are hypertension and metabolic syndrome. This study aimed to evaluate the influence of a high-caloric diet, left ventricle (LV) chronic pressure overload, and their combination on right ventricle (RV) structure and function. Methods: Wistar rats (60-80g) were subjected to ascending aorta constriction (Ba) or sham ...
Elshorbagy Amany K AK Department of Pharmacology, University of Oxford, Mansfield Road, Oxford, OX1 3QT, UK, - - 2014
Plasma concentrations of several amino acids are elevated in human obesity and insulin resistance, but there is no conclusive evidence on whether the amino acid alterations are causal. Dietary restriction of the essential SAA methionine (MR) in rats produces a hypermetabolic phenotype, with an integrated set of transcriptional changes in ...
Huang Li - - 2014
This study was conducted to evaluate the contributions of fat addition levels and storage duration at -18°C to the oxidation and physicochemical changes of frozen pork dumpling filler. With an increase in the fat addition, thiobarbituric acid-reactive substances and carbonyl production increased (P<0.05), the transition temperatures (Tmax) shifted to lower ...
Ankarfeldt Mikkel Z MZ Institute of Preventive Medicine, Bispebjerg and Frederiksberg Hospital, the Capital Region, Copenhagen, Denmark; Faculty of Medical and Health Sciences, University of Copenhagen, Copenhagen, - - 2014
To investigate if dietary protein and degree of adiposity interacts in relation to change in body weight and waist circumference (WC) in the general population. In total 22,433 middle-aged individuals with dietary assessment at baseline and anthropometry at baseline and at follow-up about 5 years later were analyzed with multiple ...
Mani Preethi P Department of Cardiovascular Medicine, Cleveland Clinic Foundation, Cleveland, - - 2014
High-density lipoprotein cholesterol (HDL-C) and apolipoprotein A-I (apoA-I) levels are inversely associated with adverse cardiovascular outcomes. Associations between these HDL-C-related measurements and coronary plaque progression have not been studied. We performed a retrospective analysis of 2,566 statin-treated patients with angiographic coronary artery disease who underwent serial evaluation of atheroma burden ...
Duggan Catherine C Epidemiology Program, Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, WA, 98109, - - 2014
Obesity and weight-loss are associated with methylation patterns in specific genes, but their effect on Long Interspersed Nuclear Elements (LINE-1) methylation, a measure of global methylation is largely unknown. Three hundred overweight/obese post-menopausal women (50-75 years) were part of a completed, 1-year randomized controlled trial, comparing independent and combined effects ...
Joseph Jalaja J Diabetes, Endocrinology, and Obesity Branch, National Institute of Diabetes and Digestive and Kidney - - 2014
Context: There is an inverse relationship between triglycerides and high density lipoprotein (HDL-C) in insulin resistance, such that improvement in insulin resistance decreases triglycerides and increases HDL-C. Patients with lipodystrophy have extreme insulin resistance with high triglycerides and low HDL-C. Leptin replacement in lipodystrophy leads to a marked decrease in ...
Cantalapiedra-Hijar G G Institut National de la Recherche Agronomique, UMR 1213 INRA-VetAgroSup, Unité Mixte de Recherches sur les Herbivores, 63122 St Genès Champanelle, France. Electronic address: - - 2014
Five mid-lactation multicatheterized Jersey cows were used in a 4 × 4 Latin square design to investigate whether the increase in milk N yield associated with diets rich in starch versus fiber could originate from changes in the splanchnic AA metabolism and if these changes depended upon the dietary crude ...
Ryu Na Hee - - 2014
High level of serum cholesterol is considered to be a major risk factor for cardiovascular disease (CVD). A double-blinded, randomized, placebo-controlled trial was performed to test the hypothesis that a daily intake of Chlorella may improve serum lipid profile through enhancement of serum carotenoid concentration in mildly hypercholesterolemic subjects. Eligible ...
Naumann Elise E Department of Archaeology, Conservation and History, University of Oslo, - - 2014
Human remains representing 33 individuals buried along the coast in northern Norway were analyzed for diet composition using collagen stable carbon and nitrogen isotope analysis. Where possible, both teeth and bone were included to investigate whether there were dietary changes from childhood to adulthood. A general shift was documented from ...
Estes E Harvey EH Duke University Medical Center, Durham, NC. Electronic address: - - 2014
In 1940, a young German refugee physician scientist at Duke University in Durham, North Carolina began to treat patients with accelerated or "malignant" hypertension with a radical diet consisting of only white rice and fruit, with strikingly favorable results. He reported rapid reduction in blood pressure, rapid improvement in renal ...
Mateo-Gallego Rocío R Unidad de Lípidos and Laboratorio de Investigación Molecular, Hospital Universitario Miguel Servet, Instituto Aragonés de Ciencias de la Salud, Zaragoza, Spain - - 2014
The effect of weight loss on lipids differs among individuals, although whether it can modify the management of hereditary hyperlipidemias has not yet been explored. The objective of this study was to examine the effect of weight loss on cholesterol metabolism, assessed by circulating noncholesterol sterols, in overweight adults with ...
Dossi Camila G CG Molecular and Clinical Pharmacology Program, Institute of Biomedical Sciences, Faculty of Medicine, University of Chile, Santiago, - - 2014
Nonalcoholic fatty liver disease is characterized by an abnormal accumulation of triacylglycerides in the liver in absence of significant alcohol consumption. Under these conditions, it has been observed an impaired bioavailability of hepatic n-3 long-chain polyunsaturated fatty acids (LCPUFAs). The aim of this study was to test the reversion of ...
Ankarfeldt M Z MZ 1] Institute of Preventive Medicine, Bispebjerg and Frederiksberg Hospital, The Capital Region, Copenhagen, Denmark [2] Faculty of Medical and Health Sciences, University of Copenhagen, - - 2014
Background:In contrast to the physiological expectation, observational studies show that greater protein intake is associated with subsequent body weight (BW) gain. An increase in fat-free mass (FFM) due to anabolic effects of protein could explain this.Objective:To examine associations between protein intake and subsequent changes in fat mass (FM) and FFM ...
Carnahan S S School of Health, Nursing and Midwifery, University of Southern Queensland, Toowoomba, AUSTRALIA - - - 2014
Obesity was probably rare in ancient times, with the current increase starting in the Industrial Revolution of the eighteenth century, and becoming much more widespread from about 1950, so concurrent with the increased consumption of carbohydrates from cereals in the Green Revolution. However, dietary components such as oligosaccharides from plants ...
Rico D E DE Department of Dairy and Animal Science, Penn State University, University Park - - 2014
Changes in milk composition during a milking are well characterized, but variation in milk fatty acid (FA) profile is not well described and may affect the accuracy of in-line milk composition analyzers and could potentially be used for selective segregation of milk. Within-milking samples were collected from 8 multiparous high-producing ...
Thiebaud Nicolas N Department of Biological Science and Program in Neuroscience, Florida State University, Tallahassee, Florida - - 2014
Currently, 65% of Americans are overweight, which leads to well-supported cardiovascular and cognitive declines. Little, however, is known concerning obesity's impact on sensory systems. Because olfaction is linked with ingestive behavior to guide food choice, its potential dysfunction during obesity could evoke a positive feedback loop to perpetuate poor ingestive ...
Murata Ryosuke - - 2014
To clarify the cause of sex change recovery after withdrawal of androgen treatment, immature female Malabar grouper were fed a diet containing 17alpha-methyltestosterone (MT) at 50 µg/g for 7 mo and then a normal diet for 6 mo. MT brought about precocious sex change from immature ovaries to mature testes ...
Xu Jing-Xiu JX College of Veterinary Medicine, Northeast Agricultural University, Harbin, 150030, People's Republic of - - 2014
To determine the relationship between dietary selenium (Se) deficiency or excess and liver hydrogen peroxide (H2O2) metabolism in chickens, 1-day-old chickens received insufficient Se (0.028 mg Se per kg of diet) or excess Se (3.0 or 5.0 mg Se per kg of diet) in their diets for 8 weeks. Body and liver weight ...
Halliday Tanya M TM Department of Human Nutrition, Foods and Exercise, Virginia Tech, Blacksburg VA 24061, United States. Electronic address: - - 2014
Engagement in one type of health behavior change may exert a "spillover" effect resulting in other behavior changes. Few studies have examined dietary intake following prolonged training, and none have evaluated spontaneous dietary changes beyond alterations in energy or macronutrient intake following initiation of strength/resistance training (RT). The purpose of ...
Hankonen Nelli N Behavioural Science Group, Primary Care Unit, Department of Public Health and Primary Care, Institute of Public Health, University of Cambridge, Robinson Way, Cambridge, CB2 0SR, UK, - - 2014
Meta-analyses have identified promising behavior change techniques (BCTs) in changing obesity-related behaviors from intervention descriptions. However, it is unclear whether these BCTs are used by intervention participants and are related to outcomes. The purpose of this study is to investigate BCT use by participants of an intervention targeting physical activity ...
Barte Jeroen C M JC Centre for Nutrition, Prevention, and Health Services, National Institute for Public Health and the Environment, P.O. Box 1, 3720 BA, Bilthoven, the Netherlands, - - 2014
Lifestyle interventions are effective for weight loss and are recommended for persons with a body mass index (BMI) of 25-40 kg m(-2). However, this group is very heterogeneous, which could influence outcomes from lifestyle interventions. In this systematic review, differences in 1-year weight change and percentage weight change after lifestyle interventions were ...
Doménech Mónica M From the Lipid Clinic, Endocrinology and Nutrition Service (M.D., A.S.-V., E.R.) and Hypertension and Vascular Risk Unit, Department of Internal Medicine (M.D., R.E., A.C.), Institut d'Investigacions Biomèdiques August Pi Sunyer (IDIBAPS), Hospital Clínic, Barcelona, Spain; Ciber Fisiopatología de la Obesidad y Nutrición (CIBERobn), Instituto de Salud Carlos III (ISCIII), Madrid, Spain (M.D., P.R., J.L., F.J.G.d.l.C., A.S.-V., R.d.l.T., D.C., J.S.-S., V.R.-G., R.-M.L.-R., E.T., R.E., E.R.); Department of Family Medicine, Primary Care Division of Seville, San Pablo Health Center, Seville, Spain (P.R., J.L., F.J.G.d.l.C.); Cardiovascular and Nutrition Research Group, Institut de Recerca Hospital del Mar, Barcelona, Spain (R.d.l.T.); Department of Preventive Medicine, University of Valencia, Valencia, Spain (D.C.); Human Nutrition Department, Hospital Universitari Sant Joan, Institut d'Investigació Sanitaria Pere Virgili, Universitat Rovira i Virgili, Reus, Spain (J.S.-S.); Instituto de la Grasa, Consejo Superior de Investigaciones Cientificas, Seville, Spain (V.R.-G.); Department of Nutrition and Food Science, School of Pharmacy, XaRTA, INSA, University of Barcelona, Barcelona, Spain (R.-M.L.-R.); and Department of Preventive Medicine and Public Health, Facultad de Medicina-Clínica, Universidad de Navarra, Pamplona, Spain - - 2014
The PREvención con DIeta MEDiterránea (PREDIMED) trial showed that Mediterranean diets (MedDiets) supplemented with either extravirgin olive oil or nuts reduced cardiovascular events, particularly stroke, compared with a control, lower fat diet. The mechanisms of cardiovascular protection remain unclear. We evaluated the 1-year effects of supplemented MedDiets on 24-hour ambulatory ...
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